☰

Lauren A. Hirao, Ph.D. - Publications

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
DNA vaccine, HIV
Tree Info Grants Similar researchers PubMed Report error

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Weber MG, Walters-Laird CJ, Kol A, Santos Rocha C, Hirao LA, Mende A, Balan B, Arredondo J, Elizaldi SR, Iyer SS, Tarantal A, Dandekar S. Gut germinal center regeneration and enhanced anti-viral immunity by mesenchymal stem/stromal cells in SIV infection. Jci Insight. PMID 34014838 DOI: 10.1172/jci.insight.149033  0.384
2019 Crakes KR, Santos Rocha C, Grishina I, Hirao LA, Napoli E, Gaulke CA, Fenton A, Datta S, Arredondo J, Marco ML, Sankaran-Walters S, Cortopassi G, Giulivi C, Dandekar S. PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31740620 DOI: 10.1096/Fasebj.2020.34.S1.02382  0.411
2018 Santos Rocha C, Hirao LA, Weber MG, Méndez-Lagares G, Chang WLW, Jiang G, Deere JD, Sparger EE, Roberts J, Barry PA, Hartigan-O'Connor DJ, Dandekar S. Subclinical cytomegalovirus infection associates with altered host immunity, gut microbiota and vaccine responses. Journal of Virology. PMID 29669841 DOI: 10.1128/Jvi.00167-18  0.477
2017 Jiang G, Santos Rocha C, Hirao LA, Mendes EA, Tang Y, Thompson GR, Wong JK, Dandekar S. HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection. Mbio. 8. PMID 28465428 DOI: 10.1128/Mbio.01518-16  0.442
2016 Golomb BL, Hirao LA, Dandekar S, Marco ML. Gene expression of Lactobacillus plantarum and the commensal microbiota in the ileum of healthy and early SIV-infected rhesus macaques. Scientific Reports. 6: 24723. PMID 27102350 DOI: 10.1038/Srep24723  0.364
2015 Glavan TW, Gaulke CA, Santos Rocha C, Sankaran-Walters S, Hirao LA, Raffatellu M, Jiang G, Bäumler AJ, Goulart LR, Dandekar S. Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. Mucosal Immunology. PMID 26376368 DOI: 10.1038/Mi.2015.92  0.436
2015 Glavan TW, Gaulke CA, Hirao LA, Sankaran-Walters S, Dandekar S. SIV-infection-driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis. Journal of Medical Primatology. 44: 241-52. PMID 26275157 DOI: 10.1111/Jmp.12187  0.322
2014 Hirao LA, Grishina I, Bourry O, Hu WK, Somrit M, Sankaran-Walters S, Gaulke CA, Fenton AN, Li JA, Crawford RW, Chuang F, Tarara R, Marco ML, Bäumler AJ, Cheng H, et al. Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption. Plos Pathogens. 10: e1004311. PMID 25166758 DOI: 10.1371/Journal.Ppat.1004311  0.425
2013 Nagy LH, Grishina I, Macal M, Hirao LA, Hu WK, Sankaran-Walters S, Gaulke CA, Pollard R, Brown J, Suni M, Baumler AJ, Ghanekar S, Marco ML, Dandekar S. Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus. Plos One. 8: e72789. PMID 24023646 DOI: 10.1371/Journal.Pone.0072789  0.483
2012 Hutnick NA, Myles DJ, Hirao L, Scott VL, Ferraro B, Khan AS, Lewis MG, Miller CJ, Bett AJ, Casimiro D, Sardesai NY, Kim JJ, Shiver J, Weiner DB. An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge. Vaccine. 30: 3202-8. PMID 22406458 DOI: 10.1016/J.Vaccine.2012.02.069  0.66
2011 Hirao LA, Hokey DA, Morrow MP, Jure-Kunkel MN, Weiner DB. Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge. Plos One. 6: e24250. PMID 21935390 DOI: 10.1371/Journal.Pone.0024250  0.673
2011 Belisle SE, Yin J, Shedlock DJ, Dai A, Yan J, Hirao L, Kutzler MA, Lewis MG, Andersen H, Lank SM, Karl JA, O'Connor DH, Khan A, Sardesai N, Chang J, et al. Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine. Plos One. 6: e19681. PMID 21701683 DOI: 10.1371/Journal.Pone.0019681  0.683
2011 Hartigan-O'Connor DJ, Hirao LA, McCune JM, Dandekar S. Th17 cells and regulatory T cells in elite control over HIV and SIV. Current Opinion in Hiv and Aids. 6: 221-7. PMID 21399494 DOI: 10.1097/Coh.0B013E32834577B3  0.448
2011 Hirao LA, Draghia-Akli R, Prigge JT, Yang M, Satishchandran A, Wu L, Hammarlund E, Khan AS, Babas T, Rhodes L, Silvera P, Slifka M, Sardesai NY, Weiner DB. Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge. The Journal of Infectious Diseases. 203: 95-102. PMID 21148501 DOI: 10.1093/Infdis/Jiq017  0.653
2010 Hirao LA, Wu L, Satishchandran A, Khan AS, Draghia-Akli R, Finnefrock AC, Bett AJ, Betts MR, Casimiro DR, Sardesai NY, Kim JJ, Shiver JW, Weiner DB. Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1568-76. PMID 20551910 DOI: 10.1038/Mt.2010.112  0.663
2009 Hirao LA, Hokey DA, Weber J, Yan J, Boyer JD, Dai A, Anderson H, Lewis M, Jure-Kunkel MN, Weiner DB. P19-49. Modulation of vaccine induced responses through CTLA-4 and 41BB enhances protection in macaques following SIVmac251 challenge Retrovirology. 6: P369. DOI: 10.1186/1742-4690-6-S3-P369  0.647
2009 Hirao LA, Wu L, Khan AS, Dai A, Karl J, Lank S, Wiseman R, O'Connor D, Watkins D, Miller N, Betts MR, Sardesai NY, Boyer JD, Weiner DB. P03-11. DNA vaccination with IL-12 lowers viral replication following SIVmac251 challenge Retrovirology. 6: P28. DOI: 10.1186/1742-4690-6-S3-P28  0.577
2009 Boyer JD, Yin J, Dai A, Belisle S, Hirao L, Palermo R, Hokey D, Yan J, Weiner D. P16-36. Functional genomic immune profile of SIV DNA vaccines delivered by electroporation and combined with molecular adjuvants Retrovirology. 6: P265. DOI: 10.1186/1742-4690-6-S3-P265  0.671
2009 Hirao LA, Wu L, Satishchandran A, Khan AS, Finnefrock A, Casimiro D, Shiver J, Betts MR, Sardesai NY, Weiner DB. OA05-02. Analysis of DNA compared to Ad5 vaccination, as single and mixed modalities, demonstrates robust induction of cellular immune responses in macaques Retrovirology. 6: O32. DOI: 10.1186/1742-4690-6-S3-O32  0.667
2008 Hokey DA, Yan J, Hirao LA, Dai A, Boyer JD, Jure-Kunkel MN, Weiner DB. CLTA-4 blockade in vivo promotes the generation of short-lived effector CD8 T cells and a more persistent central memory CD4 T cell response. Journal of Medical Primatology. 37: 62-8. PMID 19187432 DOI: 10.1111/J.1600-0684.2008.00324.X  0.52
2008 Muthumani K, Choo AY, Shedlock DJ, Laddy DJ, Sundaram SG, Hirao L, Wu L, Thieu KP, Chung CW, Lankaraman KM, Tebas P, Silvestri G, Weiner DB. Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism. Journal of Virology. 82: 11536-44. PMID 18799583 DOI: 10.1128/Jvi.00485-08  0.652
2008 Draghia-Akli R, Khan AS, Brown PA, Pope MA, Wu L, Hirao L, Weiner DB. Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models. Vaccine. 26: 5230-7. PMID 18450333 DOI: 10.1016/J.Vaccine.2008.03.071  0.596
2008 Hirao LA, Wu L, Khan AS, Hokey DA, Yan J, Dai A, Betts MR, Draghia-Akli R, Weiner DB. Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques. Vaccine. 26: 3112-20. PMID 18430495 DOI: 10.1016/J.Vaccine.2008.02.036  0.651
2008 Hokey DA, Johnson FB, Smith J, Weber JL, Yan J, Hirao L, Boyer JD, Lewis MG, Makedonas G, Betts MR, Weiner DB. Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. European Journal of Immunology. 38: 1435-45. PMID 18389475 DOI: 10.1002/Eji.200737857  0.594
2008 Hirao LA, Wu L, Khan AS, Satishchandran A, Draghia-Akli R, Weiner DB. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine. 26: 440-8. PMID 18082294 DOI: 10.1016/J.Vaccine.2007.10.041  0.65
2006 Hirao L, Khan A, Wu L, Hokey D, Draghia-Akli R, Weiner DB. Increased immunogenicity of HIV vaccination with constant-current electroporation and molecular adjuvants in mice and rhesus macaques Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S85  0.675
2006 Khan AS, Hirao L, Weiner DB, Draghia-Akli R. 598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits Molecular Therapy. 13: S231. DOI: 10.1016/J.Ymthe.2006.08.672  0.57
2006 Hirao L, Khan AS, Draghia-Akli R, Weiner DB. 585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation Molecular Therapy. 13: S226. DOI: 10.1016/J.Ymthe.2006.08.659  0.659
2005 Aldaz-Carroll L, Whitbeck JC, Ponce de Leon M, Lou H, Hirao L, Isaacs SN, Moss B, Eisenberg RJ, Cohen GH. Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R. Journal of Virology. 79: 6260-71. PMID 15858010 DOI: 10.1128/Jvi.79.10.6260-6271.2005  0.337
Show low-probability matches.