Junan Li, Ph.D. - Publications

Affiliations: 
2000 Ohio State University, Columbus, Columbus, OH 
Area:
Protein Structure-Function, NMR, Enzyme Mechanism

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Poi MJ, Knobloch TJ, Li J. Deletion of RD(INK4/ARF) enhancer: A novel mutation to "inactivate" the INK4-ARF locus. Dna Repair. 57: 50-55. PMID 28688373 DOI: 10.1016/J.Dnarep.2017.06.027  0.479
2017 Poi MJ, Li J, Sborov DW, VanGundy Z, Cho YK, Lamprecht M, Pichiorri F, Phelps MA, Hofmeister CC. Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant. Molecular Carcinogenesis. PMID 28150872 DOI: 10.1002/Mc.22626  0.37
2015 Poi MJ, Knobloch TJ, Sears MT, Warner BM, Uhrig LK, Weghorst CM, Li J. Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck. Molecular Carcinogenesis. 54: 532-42. PMID 24302590 DOI: 10.1002/Mc.22119  0.449
2014 Poi MJ, Drosdeck J, Frankel WL, Muscarella P, Li J. Deletions of RDINK4/ARF enhancer in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors. Pancreas. 43: 1009-13. PMID 25003221 DOI: 10.1097/Mpa.0000000000000165  0.427
2014 Li J, Knobloch TJ, Poi MJ, Zhang Z, Davis AT, Muscarella P, Weghorst CM. Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells. Molecular Carcinogenesis. 53: 211-8. PMID 23065809 DOI: 10.1002/Mc.21965  0.487
2013 Yuan C, Guo Y, Zhu L, Guo W, Mahajan A, Weghorst CM, Li J. The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin. Biochemistry. 52: 4848-57. PMID 23777370 DOI: 10.1021/Bi4005717  0.324
2013 Poi MJ, Knobloch TJ, Yuan C, Tsai MD, Weghorst CM, Li J. Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis. Biochemical and Biophysical Research Communications. 436: 217-22. PMID 23727582 DOI: 10.1016/J.Bbrc.2013.05.078  0.625
2011 Li J, Poi MJ, Tsai MD. Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer. Biochemistry. 50: 5566-82. PMID 21619050 DOI: 10.1021/Bi200642E  0.611
2010 Li J, Guo Y. Gankyrin Oncoprotein: Structure, Function, and Involvement in Cancer. Current Chemical Biology. 4: 13-19. PMID 32775187 DOI: 10.2174/2212796811004010013  0.401
2010 Guo Y, Yuan C, Tian F, Huang K, Weghorst CM, Tsai MD, Li J. Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins. Journal of Molecular Biology. 399: 168-81. PMID 20398677 DOI: 10.1016/J.Jmb.2010.04.010  0.525
2010 Guo Y, Yuan C, Weghorst CM, Li J. IKKbeta specifically binds to P16 and phosphorylates Ser8 of P16. Biochemical and Biophysical Research Communications. 393: 504-8. PMID 20152798 DOI: 10.1016/J.Bbrc.2010.02.035  0.476
2009 Guo Y, Mahajan A, Yuan C, Joo SH, Weghorst CM, Tsai MD, Li J. Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins. Biochemistry. 48: 4050-62. PMID 19320462 DOI: 10.1021/Bi802247P  0.579
2008 Muscarella P, Bloomston M, Brewer AR, Mahajan A, Frankel WL, Ellison EC, Farrar WB, Weghorst CM, Li J. Expression of the p16INK4A/Cdkn2a gene is prevalently downregulated in human pheochromocytoma tumor specimens. Gene Expression. 14: 207-16. PMID 19110720 DOI: 10.3727/105221608786883825  0.433
2008 Li J, Warner B, Casto BC, Knobloch TJ, Weghorst CM. Tumor suppressor p16(INK4A)/Cdkn2a alterations in 7, 12-dimethylbenz(a)anthracene (DMBA)-induced hamster cheek pouch tumors. Molecular Carcinogenesis. 47: 733-8. PMID 18247379 DOI: 10.1002/Mc.20424  0.456
2007 Mahajan A, Guo Y, Yuan C, Weghorst CM, Tsai MD, Li J. Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16. Journal of Molecular Biology. 373: 990-1005. PMID 17881001 DOI: 10.1016/J.Jmb.2007.08.038  0.669
2006 Li J, Mahajan A, Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry. 45: 15168-78. PMID 17176038 DOI: 10.1021/Bi062188Q  0.533
2006 Li J, Zhu J, Melvin WS, Bekaii-Saab TS, Chen CS, Muscarella P. A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 10: 207-14. PMID 16455452 DOI: 10.1016/J.Gassur.2005.07.025  0.356
2005 Li J, Muscarella P, Joo SH, Knobloch TJ, Melvin WS, Weghorst CM, Tsai MD. Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A). Biochemistry. 44: 13246-56. PMID 16201750 DOI: 10.1021/Bi0504658  0.625
2004 Yuan C, Li J, Mahajan A, Poi MJ, Byeon IJ, Tsai MD. Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship. Biochemistry. 43: 12152-61. PMID 15379554 DOI: 10.1021/Bi049116O  0.585
2004 Li J, Melvin WS, Tsai MD, Muscarella P. The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner. Biochemistry. 43: 4394-9. PMID 15065884 DOI: 10.1021/Bi035601S  0.627
2004 Li J, Weghorst CM, Tsutsumi M, Poi MJ, Knobloch TJ, Casto BC, Melvin WS, Tsai MD, Muscarella P. Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors. Carcinogenesis. 25: 263-8. PMID 14604895 DOI: 10.1093/Carcin/Bgh007  0.584
2003 Li J, Joo SH, Tsai MD. An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4. Biochemistry. 42: 13476-83. PMID 14621993 DOI: 10.1021/Bi035390R  0.579
2003 Li J, Li H, Tsai MD. Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activity. Biochemistry. 42: 6921-8. PMID 12779347 DOI: 10.1021/Bi034369N  0.674
2003 Li J, Qin D, Knobloch TJ, Tsai MD, Weghorst CM, Melvin WS, Muscarella P. Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A. Biochemical and Biophysical Research Communications. 304: 241-7. PMID 12711305 DOI: 10.1016/S0006-291X(03)00577-1  0.704
2002 Li J, Tsai MD. Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of Rb. Biochemistry. 41: 3977-83. PMID 11900540 DOI: 10.1021/bi011550s  0.55
2001 Poi MJ, Yen T, Li J, Song H, Lang JC, Schuller DE, Pearl DK, Casto BC, Tsai MD, Weghorst CM. Somatic INK4a-ARF locus mutations: a significant mechanism of gene inactivation in squamous cell carcinomas of the head and neck. Molecular Carcinogenesis. 30: 26-36. PMID 11255261 DOI: 10.1002/1098-2744(200101)30:1<26::Aid-Mc1010>3.0.Co;2-E  0.678
2000 Yuan C, Selby TL, Li J, Byeon IJ, Tsai MD. Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data. Protein Science : a Publication of the Protein Society. 9: 1120-8. PMID 10892805 DOI: 10.1110/Ps.9.6.1120  0.568
2000 Li J, Poi MJ, Qin D, Selby TL, Byeon IJ, Tsai MD. Tumor suppressor INK4: quantitative structure-function analyses of p18INK4C as an inhibitor of cyclin-dependent kinase 4. Biochemistry. 39: 649-57. PMID 10651629 DOI: 10.1021/Bi991281U  0.711
1999 Yuan C, Li J, Selby TL, Byeon IJ, Tsai MD. Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C). Journal of Molecular Biology. 294: 201-11. PMID 10556039 DOI: 10.1006/Jmbi.1999.3231  0.62
1999 Li J, Byeon IJ, Ericson K, Poi MJ, O'Maille P, Selby T, Tsai MD. Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A. Biochemistry. 38: 2930-40. PMID 10074345 DOI: 10.1021/Bi982286E  0.74
1998 Byeon IJ, Li J, Ericson K, Selby TL, Tevelev A, Kim HJ, O'Maille P, Tsai MD. Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4. Molecular Cell. 1: 421-31. PMID 9660926 DOI: 10.1016/S1097-2765(00)80042-8  0.721
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