Louise D. McCullough, MD, PhD - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Nucleus Accumbens, Dopamine, Motivation
Website:
https://med.uth.edu/neurology/faculty/louise-d-mccullough-md-phd/

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee J, Peesh P, Quaicoe V, Tan C, Banerjee A, Mooz P, Ganesh BP, Petrosino J, Bryan RM, McCullough LD, Venna VR. Estradiol mediates colonic epithelial protection in aged mice after stroke and is associated with shifts in the gut microbiome. Gut Microbes. 15: 2271629. PMID 37910478 DOI: 10.1080/19490976.2023.2271629  0.373
2023 Conesa MPB, Blixt FW, Peesh P, Khan R, Korf J, Lee J, Jagadeesan G, Andersohn A, Das TK, Tan C, Di Gesu C, Colpo GD, Moruno-Manchón JF, McCullough LD, Bryan R, et al. Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke. Journal of Neuroinflammation. 20: 230. PMID 37805585 DOI: 10.1186/s12974-023-02887-7  0.337
2023 Kim GS, Harmon E, Gutierrez M, Stephenson J, Chauhan A, Banerjee A, Wise Z, Doan A, Wu T, Lee J, Jung JE, McCullough L, Wythe J, Marrelli S. Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke. Research Square. PMID 36824976 DOI: 10.21203/rs.3.rs-2557290/v1  0.318
2022 Tariq MB, Lee J, McCullough LD. Sex differences in the inflammatory response to stroke. Seminars in Immunopathology. PMID 36355204 DOI: 10.1007/s00281-022-00969-x  0.346
2022 Qi S, Ngwa C, Al Mamun A, Romana S, Wu T, Marrelli SP, Arnold AP, McCullough LD, Liu F. X, but not Y, Chromosomal Complement Contributes to Stroke Sensitivity in Aged Animals. Translational Stroke Research. PMID 35906327 DOI: 10.1007/s12975-022-01070-z  0.33
2022 Noh B, McCullough LD, Moruno-Manchon JF. Sex-biased autophagy as a potential mechanism mediating sex differences in ischemic stroke outcome. Neural Regeneration Research. 18: 31-37. PMID 35799505 DOI: 10.4103/1673-5374.340406  0.394
2022 Ospel JM, Schaafsma JD, Leslie-Mazwi TM, Amin-Hanjani S, Asdaghi N, Gordon-Perue GL, Couillard P, Hadidi NN, Bushnell C, McCullough LD, Goyal M. Toward a Better Understanding of Sex- and Gender-Related Differences in Endovascular Stroke Treatment: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke. 101161STR00000000000. PMID 35695016 DOI: 10.1161/STR.0000000000000411  0.338
2021 McCullough LD, Roy-O'Reilly M, Lai YJ, Patrizz A, Xu Y, Lee J, Holmes A, Kraushaar DC, Chauhan A, Sansing LH, Stonestreet BS, Zhu L, Kofler J, Lim YP, Venna VR. Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice. The Journal of Clinical Investigation. 131. PMID 34580244 DOI: 10.1172/JCI144898  0.341
2021 Patrizz AN, Moruno-Manchon JF, O'Keefe LM, Doran SJ, Patel AR, Venna VR, Tsvetkov AS, Li J, McCullough LD. Sex-Specific Differences in Autophagic Responses to Experimental Ischemic Stroke. Cells. 10. PMID 34359998 DOI: 10.3390/cells10071825  0.439
2021 Qi S, Al Mamun A, Ngwa C, Romana S, Ritzel R, Arnold AP, McCullough LD, Liu F. X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals. Journal of Neuroinflammation. 18: 70. PMID 33712031 DOI: 10.1186/s12974-021-02120-3  0.341
2021 Manwani B, Fall P, Zhu L, O'Reilly MR, Conway S, Staff I, McCullough LD. Increased P450 aromatase levels in post-menopausal women after acute ischemic stroke. Biology of Sex Differences. 12: 8. PMID 33413673 DOI: 10.1186/s13293-020-00357-w  0.368
2020 Holmes A, Xu Y, Lee J, Maniskas ME, Zhu L, McCullough LD, Venna VR. Post-Stroke Social Isolation Reduces Cell Proliferation in the Dentate Gyrus and Alters miRNA Profiles in the Aged Female Mice Brain. International Journal of Molecular Sciences. 22. PMID 33374156 DOI: 10.3390/ijms22010099  0.326
2020 Lee SM, Hudobenko J, McCullough LD, Chauhan A. Microglia depletion increase brain injury after acute ischemic stroke in aged mice. Experimental Neurology. 113530. PMID 33221396 DOI: 10.1016/j.expneurol.2020.113530  0.313
2020 Bu F, Munshi Y, Furr JW, Min JW, Qi L, Patrizz A, Spahr ZR, Urayama A, Kofler JK, McCullough LD, Li J. Activation of Neuronal Ras-Related C3 Botulinum Toxin Substrate 1 (Rac1) Improves Post-Stroke Recovery and Axonal Plasticity in Mice. Journal of Neurochemistry. PMID 32964455 DOI: 10.1111/jnc.15195  0.323
2020 Hudobenko J, Ganesh BP, Jiang J, Mohan EC, Lee S, Sheth S, Morales D, Zhu L, Kofler JK, Pautler RG, McCullough LD, Chauhan A. Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice. Aging. 12. PMID 32365331 DOI: 10.18632/aging.103122  0.314
2020 Ahnstedt H, Patrizz A, Chauhan A, Roy-O'Reilly M, Furr JW, Spychala MS, D'Aigle J, Blixt FW, Zhu L, Bravo Alegria J, McCullough LD. Sex differences in T cell immune responses, gut permeability and outcome after ischemic stroke in aged mice. Brain, Behavior, and Immunity. PMID 32058038 DOI: 10.1016/J.Bbi.2020.02.001  0.331
2020 Harris NM, Roy-O'Reilly M, Ritzel RM, Holmes A, Sansing LH, O'Keefe LM, McCullough LD, Chauhan A. Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke. Experimental Neurology. 113202. PMID 31954116 DOI: 10.1016/J.Expneurol.2020.113202  0.321
2020 Roy-O'Reilly MA, Ahnstedt H, Spychala MS, Munshi Y, Aronowski J, Sansing LH, McCullough LD. Aging exacerbates neutrophil pathogenicity in ischemic stroke. Aging. 12: 436-461. PMID 31927534 DOI: 10.18632/aging.102632  0.317
2020 Fournier LE, Hopping GC, Zhu L, Perez-Pinzon MA, Ovbiagele B, McCullough LD, Sharrief AZ. Females Are Less Likely Invited Speakers to the International Stroke Conference: Time's Up to Address Sex Disparity. Stroke. STROKEAHA119027016. PMID 31902331 DOI: 10.1161/Strokeaha.119.027016  0.376
2019 Al Mamun A, Chauhan A, Qi S, Ngwa C, Xu Y, Sharmeen R, Hazen AL, Li J, Aronowski JA, McCullough LD, Liu F. Microglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31892541 DOI: 10.1073/Pnas.1914742117  0.312
2019 Ahnstedt H, McCullough LD. The impact of sex and age on T cell immunity and ischemic stroke outcomes. Cellular Immunology. 103960. PMID 31519365 DOI: 10.1016/J.Cellimm.2019.103960  0.35
2019 Bu F, Min JW, Munshi Y, Lai YJ, Qi L, Urayama A, McCullough LD, Li J. Activation of endothelial ras-related C3 botulinum toxin substrate 1 (Rac1) improves post-stroke recovery and angiogenesis via activating Pak1 in mice. Experimental Neurology. 113059. PMID 31499064 DOI: 10.1016/J.Expneurol.2019.113059  0.302
2019 Sheth SA, Lee S, Warach SJ, Gralla J, Jahan R, Goyal M, Nogueira RG, Zaidat OO, Pereira VM, Siddiqui A, Lutsep H, Liebeskind DS, McCullough LD, Saver JL. Sex Differences in Outcome After Endovascular Stroke Therapy for Acute Ischemic Stroke. Stroke. STROKEAHA118023867. PMID 31412752 DOI: 10.1161/Strokeaha.118.023867  0.341
2019 Colpo GD, Venna VR, McCullough LD, Teixeira AL. Systematic Review on the Involvement of the Kynurenine Pathway in Stroke: Pre-clinical and Clinical Evidence. Frontiers in Neurology. 10: 778. PMID 31379727 DOI: 10.3389/Fneur.2019.00778  0.328
2019 Fournier LE, Zhu L, Perez-Pinzon MA, Ovbiagele B, McCullough LD, Sharrief AZ. Abstract WP363: Females are Significantly Less Likely to be Invited as Speakers to the International Stroke Conference: Time’s Up to Address Sex Disparity Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Wp363  0.401
2019 Fournier LE, Zhu L, Perez-Pinzon MA, Ovbiagele B, McCullough LD, Sharrief AZ. Abstract TP349: Submitted and Accepted Abstracts by Sex at the International Stroke Conference: Analysis of Trends From 2014-2018 Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.Tp349  0.307
2019 Venna VR, Urayama A, d'Aigle J, Lee J, Lim Y, McCullough LD. Abstract 134: Sex Differences in the Neuroprotective Effects of IAIP are Potentially Driven by Differences in Blood Brain Barrier Permeability after Stroke Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.134  0.316
2018 Sun P, Bu F, Min JW, Munshi Y, Howe MD, Liu L, Koellhoffer EC, Qi L, McCullough LD, Li J. Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase (CaMKK) Exacerbates Impairment of Endothelial Cell and Blood-Brain Barrier after Stroke. The European Journal of Neuroscience. PMID 30422362 DOI: 10.1111/Ejn.14223  0.305
2018 Bushnell CD, Chaturvedi S, Gage KR, Herson PS, Hurn PD, Jiménez MC, Kittner SJ, Madsen TE, McCullough LD, McDermott M, Reeves MJ, Rundek T. Sex differences in stroke: Challenges and opportunities. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18793324. PMID 30114967 DOI: 10.1177/0271678X18793324  0.35
2018 Memon A, McCullough LD. Cerebral Circulation in Men and Women. Advances in Experimental Medicine and Biology. 1065: 279-290. PMID 30051391 DOI: 10.1007/978-3-319-77932-4_18  0.389
2018 Roy-O'Reilly M, McCullough LD. Age and Sex Are Critical Factors in Ischemic Stroke Pathology. Endocrinology. PMID 30010821 DOI: 10.1210/En.2018-00465  0.333
2018 Chauhan A, Hudobenko J, Al Mamun A, Koellhoffer EC, Patrizz A, Ritzel RM, Ganesh BP, McCullough LD. Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke. Journal of Neuroinflammation. 15: 148. PMID 29776451 DOI: 10.1186/S12974-018-1188-3  0.321
2018 Ritzel RM, Lai YJ, Crapser JD, Patel AR, Schrecengost A, Grenier JM, Mancini NS, Patrizz A, Jellison ER, Morales-Scheihing D, Venna VR, Kofler JK, Liu F, Verma R, McCullough LD. Aging alters the immunological response to ischemic stroke. Acta Neuropathologica. PMID 29752550 DOI: 10.1007/S00401-018-1859-2  0.303
2018 Verma R, Ritzel RM, Crapser J, Friedler BD, McCullough LD. Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke. Translational Stroke Research. PMID 29302794 DOI: 10.1007/S12975-017-0603-X  0.361
2018 Venna VR, Roy-O’Reilly MA, Howe MD, Lee J, Zhu L, Stonestreet B, Lim Y, McCullough LD. Abstract 71: Circulating Inter-alpha Inhibitor Protein Levels Decline After Stroke in Humans: Exogenous Supplementation is Protective in Multiple Animal Models of Ischemic Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.71  0.32
2018 Hudobenko J, Chauhan A, McCullough L. Abstract 28: Inhibition of Interleukin-6 Signaling With Tocilizumab Ameliorates Ischemic Stroke Damage in Aged Male and Female Mice Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.28  0.386
2017 Chauhan A, Al Mamun A, Spiegel G, Harris N, Zhu L, McCullough LD. Splenectomy protects aged mice from injury after experimental stroke. Neurobiology of Aging. 61: 102-111. PMID 29059593 DOI: 10.1016/J.Neurobiolaging.2017.09.022  0.328
2017 Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, ... ... McCullough LD, et al. Translational Stroke Research: Vision and Opportunities. Stroke. PMID 28751554 DOI: 10.1161/Strokeaha.117.017112  0.304
2017 Verma R, Cronin CG, Hudobenko J, Venna VR, McCullough LD, Liang BT. Deletion of the P2X4 receptor is neuroprotective acutely, but induces a depressive phenotype during recovery from ischemic stroke. Brain, Behavior, and Immunity. PMID 28751018 DOI: 10.1016/J.Bbi.2017.07.155  0.305
2017 Ritzel RM, Patel AR, Spychala M, Verma R, Crapser J, Koellhoffer EC, Schrecengost A, Jellison ER, Zhu L, Venna VR, McCullough LD. Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk. Proceedings of the National Academy of Sciences of the United States of America. PMID 28645895 DOI: 10.1073/Pnas.1607002114  0.389
2017 Roy-O'Reilly M, Ritzel RM, Conway SE, Staff I, Fortunato G, McCullough LD. CCL11 (Eotaxin-1) Levels Predict Long-Term Functional Outcomes in Patients Following Ischemic Stroke. Translational Stroke Research. PMID 28634890 DOI: 10.1007/S12975-017-0545-3  0.306
2017 Bravo-Alegria J, McCullough LD, Liu F. Sex differences in stroke across the lifespan: The role of T lymphocytes. Neurochemistry International. PMID 28131898 DOI: 10.1016/J.Neuint.2017.01.009  0.307
2017 Spychala MS, Honarpisheh P, McCullough LD. Sex differences in neuroinflammation and neuroprotection in ischemic stroke. Journal of Neuroscience Research. 95: 462-471. PMID 27870410 DOI: 10.1002/Jnr.23962  0.327
2016 McCullough LD, Mirza MA, Xu Y, Bentivegna K, Steffens EB, Ritzel R, Liu F. Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones. Aging. PMID 27405096  0.363
2016 Ahnstedt H, McCullough LD, Cipolla MJ. The Importance of Considering Sex Differences in Translational Stroke Research. Translational Stroke Research. PMID 26830778 DOI: 10.1007/S12975-016-0450-1  0.35
2015 Conway SE, Roy-O'Reilly M, Friedler B, Staff I, Fortunato G, McCullough LD. Sex differences and the role of IL-10 in ischemic stroke recovery. Biology of Sex Differences. 6: 17. PMID 26462256 DOI: 10.1186/S13293-015-0035-9  0.302
2015 Kim GS, Yang L, Zhang G, Zhao H, Selim M, McCullough LD, Kluk MJ, Sanchez T. Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke. Nature Communications. 6: 7893. PMID 26243335 DOI: 10.1038/Ncomms8893  0.324
2015 Ritzel RM, Patel AR, Grenier JM, Crapser J, Verma R, Jellison ER, McCullough LD. Functional differences between microglia and monocytes after ischemic stroke. Journal of Neuroinflammation. 12: 106. PMID 26022493 DOI: 10.1186/S12974-015-0329-1  0.317
2015 Mirza MA, Ritzel R, Xu Y, McCullough LD, Liu F. Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy. Journal of Neuroinflammation. 12: 32. PMID 25889641 DOI: 10.1186/S12974-015-0251-6  0.398
2015 Doran SJ, Trammel C, Benashaski SE, Venna VR, McCullough LD. Ultrasonic vocalization changes and FOXP2 expression after experimental stroke. Behavioural Brain Research. 283: 154-61. PMID 25644653 DOI: 10.1016/J.Bbr.2015.01.035  0.361
2015 Manwani B, Bentivegna K, Benashski SE, Venna VR, Xu Y, Arnold AP, McCullough LD. Sex differences in ischemic stroke sensitivity are influenced by gonadal hormones, not by sex chromosome complement. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 221-9. PMID 25388681 DOI: 10.1038/Jcbfm.2014.186  0.437
2015 Venna VR, McCullough LD. Role of social factors on cell death, cerebral plasticity and recovery after stroke. Metabolic Brain Disease. 30: 497-506. PMID 24748365 DOI: 10.1007/S11011-014-9544-1  0.305
2014 Liu L, McCullough L, Li J. Genetic deletion of calcium/calmodulin-dependent protein kinase kinase β (CaMKK β) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice. Bmc Neuroscience. 15: 118. PMID 25331941 DOI: 10.1186/S12868-014-0118-2  0.365
2014 Verma R, Friedler BD, Harris NM, McCullough LD. Pair housing reverses post-stroke depressive behavior in mice. Behavioural Brain Research. 269: 155-63. PMID 24793492 DOI: 10.1016/J.Bbr.2014.04.044  0.317
2014 Venna VR, Li J, Hammond MD, Mancini NS, McCullough LD. Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke. The European Journal of Neuroscience. 39: 2129-38. PMID 24649970 DOI: 10.1111/Ejn.12556  0.33
2014 Roy-O'Reilly M, McCullough LD. Sex differences in stroke: the contribution of coagulation. Experimental Neurology. 259: 16-27. PMID 24560819 DOI: 10.1016/J.Expneurol.2014.02.011  0.316
2014 Venna VR, Xu Y, Doran SJ, Patrizz A, McCullough LD. Social interaction plays a critical role in neurogenesis and recovery after stroke. Translational Psychiatry. 4: e351. PMID 24473442 DOI: 10.1038/Tp.2013.128  0.335
2013 Koellhoffer EC, McCullough LD. The effects of estrogen in ischemic stroke. Translational Stroke Research. 4: 390-401. PMID 24323337 DOI: 10.1007/S12975-012-0230-5  0.301
2013 Manwani B, Liu F, Scranton V, Hammond MD, Sansing LH, McCullough LD. Differential effects of aging and sex on stroke induced inflammation across the lifespan. Experimental Neurology. 249: 120-31. PMID 23994069 DOI: 10.1016/J.Expneurol.2013.08.011  0.352
2013 McCullough LD, Tarabishy S, Liu L, Benashski S, Xu Y, Ribar T, Means A, Li J. Inhibition of calcium/calmodulin-dependent protein kinase kinase β and calcium/calmodulin-dependent protein kinase IV is detrimental in cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 44: 2559-66. PMID 23868268 DOI: 10.1161/Strokeaha.113.001030  0.302
2013 Patel AR, Ritzel R, McCullough LD, Liu F. Microglia and ischemic stroke: a double-edged sword. International Journal of Physiology, Pathophysiology and Pharmacology. 5: 73-90. PMID 23750306  0.301
2013 Siegel CS, McCullough LD. NAD+ and nicotinamide: sex differences in cerebral ischemia. Neuroscience. 237: 223-31. PMID 23403179 DOI: 10.1016/J.Neuroscience.2013.01.068  0.787
2013 Turtzo LC, Li J, Persky R, Benashski S, Weston G, Bucala R, Venna VR, McCullough LD. Deletion of macrophage migration inhibitory factor worsens stroke outcome in female mice. Neurobiology of Disease. 54: 421-31. PMID 23376686 DOI: 10.1016/J.Nbd.2013.01.016  0.447
2013 Persky RW, Liu F, Xu Y, Weston G, Levy S, Roselli CE, McCullough LD. Neonatal testosterone exposure protects adult male rats from stroke. Neuroendocrinology. 97: 271-82. PMID 23051877 DOI: 10.1159/000343804  0.399
2013 Ritzel RM, Capozzi LA, McCullough LD. Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke. Hormones and Behavior. 63: 238-53. PMID 22561337 DOI: 10.1016/J.Yhbeh.2012.04.007  0.403
2012 Liu F, McCullough LD. Interactions between age, sex, and hormones in experimental ischemic stroke. Neurochemistry International. 61: 1255-65. PMID 23068990 DOI: 10.1016/J.Neuint.2012.10.003  0.342
2012 White BJ, Tarabishy S, Venna VR, Manwani B, Benashski S, McCullough LD, Li J. Protection from cerebral ischemia by inhibition of TGFβ-activated kinase. Experimental Neurology. 237: 238-45. PMID 22683931 DOI: 10.1016/J.Expneurol.2012.05.019  0.351
2012 Liu F, Turtzo LC, Li J, Regard J, Worley P, Zeevi N, McCullough LD. Loss of vascular early response gene reduces edema formation after experimental stroke. Experimental & Translational Stroke Medicine. 4: 12. PMID 22681709 DOI: 10.1186/2040-7378-4-12  0.343
2012 Manwani B, McCullough LD. Estrogen in ischaemic stroke: the debate continues. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 19: 1276-7. PMID 22564142 DOI: 10.1111/J.1468-1331.2012.03746.X  0.322
2012 Venna VR, Li J, Benashski SE, Tarabishy S, McCullough LD. Preconditioning induces sustained neuroprotection by downregulation of adenosine 5'-monophosphate-activated protein kinase. Neuroscience. 201: 280-7. PMID 22120436 DOI: 10.1016/J.Neuroscience.2011.11.014  0.303
2012 Liu F, Benashski SE, Xu Y, Siegel M, McCullough LD. Effects of chronic and acute oestrogen replacement therapy in aged animals after experimental stroke. Journal of Neuroendocrinology. 24: 319-30. PMID 22053957 DOI: 10.1111/J.1365-2826.2011.02248.X  0.369
2011 Hill CA, Alexander ML, McCullough LD, Fitch RH. Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats. Developmental Neuroscience. 33: 494-504. PMID 22041713 DOI: 10.1159/000331651  0.367
2011 Turtzo LC, Siegel C, McCullough LD. X chromosome dosage and the response to cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13255-9. PMID 21917808 DOI: 10.1523/Jneurosci.0621-11.2011  0.762
2011 Manwani B, Liu F, Xu Y, Persky R, Li J, McCullough LD. Functional recovery in aging mice after experimental stroke. Brain, Behavior, and Immunity. 25: 1689-700. PMID 21756996 DOI: 10.1016/J.Bbi.2011.06.015  0.345
2011 Siegel C, Li J, Liu F, Benashski SE, McCullough LD. miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America. 108: 11662-7. PMID 21709246 DOI: 10.1073/Pnas.1102635108  0.764
2011 Manwani B, McCullough LD. Sexual dimorphism in ischemic stroke: lessons from the laboratory. Women's Health (London, England). 7: 319-39. PMID 21612353 DOI: 10.2217/Whe.11.22  0.362
2011 Li J, Benashski S, McCullough LD. Post-stroke hypothermia provides neuroprotection through inhibition of AMP-activated protein kinase. Journal of Neurotrauma. 28: 1281-8. PMID 21446786 DOI: 10.1089/Neu.2011.1751  0.361
2011 Liu F, McCullough LD. Middle cerebral artery occlusion model in rodents: methods and potential pitfalls. Journal of Biomedicine & Biotechnology. 2011: 464701. PMID 21331357 DOI: 10.1155/2011/464701  0.302
2011 Liu F, Lang J, Li J, Benashski SE, Siegel M, Xu Y, McCullough LD. Sex differences in the response to poly(ADP-ribose) polymerase-1 deletion and caspase inhibition after stroke. Stroke; a Journal of Cerebral Circulation. 42: 1090-6. PMID 21311064 DOI: 10.1161/Strokeaha.110.594861  0.479
2011 Siegel C, McCullough LD. NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death? Acta Physiologica (Oxford, England). 203: 225-34. PMID 21091637 DOI: 10.1111/J.1748-1716.2010.02229.X  0.74
2011 Li J, Siegel M, Yuan M, Zeng Z, Finnucan L, Persky R, Hurn PD, McCullough LD. Estrogen enhances neurogenesis and behavioral recovery after stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 413-25. PMID 20940729 DOI: 10.1038/Jcbfm.2010.181  0.382
2010 Li J, Benashski SE, Venna VR, McCullough LD. Effects of metformin in experimental stroke. Stroke; a Journal of Cerebral Circulation. 41: 2645-52. PMID 20847317 DOI: 10.1161/Strokeaha.110.589697  0.346
2010 Siegel C, Turtzo C, McCullough LD. Sex differences in cerebral ischemia: possible molecular mechanisms. Journal of Neuroscience Research. 88: 2765-74. PMID 20698025 DOI: 10.1002/Jnr.22406  0.755
2010 Li J, Benashski SE, Siegel C, Liu F, McCullough LD. Adenosine monophosphate activated protein kinase inhibition is protective in both sexes after experimental stroke. Neuroscience Letters. 482: 62-5. PMID 20621158 DOI: 10.1016/J.Neulet.2010.07.007  0.783
2010 Liu F, Akella P, Benashski SE, Xu Y, McCullough LD. Expression of Na-K-Cl cotransporter and edema formation are age dependent after ischemic stroke. Experimental Neurology. 224: 356-61. PMID 20406636 DOI: 10.1016/J.Expneurol.2010.04.010  0.328
2010 Turtzo LC, McCullough LD. Sex-specific responses to stroke. Future Neurology. 5: 47-59. PMID 20190872 DOI: 10.2217/Fnl.09.66  0.424
2009 Yuan M, Siegel C, Zeng Z, Li J, Liu F, McCullough LD. Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke. Experimental Neurology. 217: 210-8. PMID 19268668 DOI: 10.1016/J.Expneurol.2009.02.012  0.788
2009 Liu F, Li Z, Li J, Siegel C, Yuan R, McCullough LD. Sex differences in caspase activation after stroke. Stroke; a Journal of Cerebral Circulation. 40: 1842-8. PMID 19265047 DOI: 10.1161/Strokeaha.108.538686  0.788
2009 Liu F, Yuan R, Benashski SE, McCullough LD. Changes in experimental stroke outcome across the life span. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 792-802. PMID 19223913 DOI: 10.1038/Jcbfm.2009.5  0.408
2009 Li J, McCullough LD. Sex differences in minocycline-induced neuroprotection after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 670-4. PMID 19190654 DOI: 10.1038/Jcbfm.2009.3  0.424
2009 McCullough LD, Koerner IP, Hurn PD. Effects of gender and sex steroids on ischemic injury. Handbook of Clinical Neurology. 92: 149-69. PMID 18790274 DOI: 10.1016/S0072-9752(08)01908-8  0.419
2008 Turtzo LC, McCullough LD. Sex differences in stroke. Cerebrovascular Diseases (Basel, Switzerland). 26: 462-74. PMID 18810232 DOI: 10.1159/000155983  0.372
2008 Lang JT, McCullough LD. Pathways to ischemic neuronal cell death: are sex differences relevant? Journal of Translational Medicine. 6: 33. PMID 18573200 DOI: 10.1186/1479-5876-6-33  0.421
2008 Li J, Lang J, Zeng Z, McCullough LD. Akt1 gene deletion and stroke. Journal of the Neurological Sciences. 269: 105-12. PMID 18258266 DOI: 10.1016/J.Jns.2007.12.034  0.397
2007 Li J, Zeng Z, Viollet B, Ronnett GV, McCullough LD. Neuroprotective effects of adenosine monophosphate-activated protein kinase inhibition and gene deletion in stroke. Stroke; a Journal of Cerebral Circulation. 38: 2992-9. PMID 17901380 DOI: 10.1161/Strokeaha.107.490904  0.338
2005 Craft TK, Glasper ER, McCullough L, Zhang N, Sugo N, Otsuka T, Hurn PD, DeVries AC. Social interaction improves experimental stroke outcome. Stroke; a Journal of Cerebral Circulation. 36: 2006-11. PMID 16100018 DOI: 10.1161/01.Str.0000177538.17687.54  0.35
2005 Li H, Pin S, Zeng Z, Wang MM, Andreasson KA, McCullough LD. Sex differences in cell death. Annals of Neurology. 58: 317-21. PMID 15988750 DOI: 10.1002/Ana.20538  0.327
2005 McCullough LD, Zeng Z, Blizzard KK, Debchoudhury I, Hurn PD. Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 502-12. PMID 15689952 DOI: 10.1038/Sj.Jcbfm.9600059  0.453
2004 Murphy SJ, McCullough LD, Smith JM. Stroke in the female: role of biological sex and estrogen. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 45: 147-59. PMID 15111734 DOI: 10.1093/Ilar.45.2.147  0.346
2004 Li X, Blizzard KK, Zeng Z, DeVries AC, Hurn PD, McCullough LD. Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender. Experimental Neurology. 187: 94-104. PMID 15081592 DOI: 10.1016/J.Expneurol.2004.01.004  0.303
2003 McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD. Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8701-5. PMID 14507969  0.401
2003 McCullough LD, Hurn PD. Estrogen and ischemic neuroprotection: an integrated view. Trends in Endocrinology and Metabolism: Tem. 14: 228-35. PMID 12826329 DOI: 10.1016/S1043-2760(03)00076-6  0.31
2003 McCullough LD, Blizzard K, Simpson ER, Öz OK, Hurn PD. Aromatase Cytochrome P450 and Extragonadal Estrogen Play a Role in Ischemic Neuroprotection The Journal of Neuroscience. 23: 8701-8705. DOI: 10.1523/Jneurosci.23-25-08701.2003  0.344
2001 McCullough LD, Alkayed NJ, Traystman RJ, Williams MJ, Hurn PD. Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke; a Journal of Cerebral Circulation. 32: 796-802. PMID 11239204 DOI: 10.1161/01.Str.32.3.796  0.3
2001 McCullough LD, Beauchamp NB, Wityk R. Recent advances in the diagnosis and treatment of stroke. Survey of Ophthalmology. 45: 317-30. PMID 11166343 DOI: 10.1016/S0039-6257(00)00188-0  0.302
1995 Salamone JD, Kurth P, McCullough LD, Sokolowski JD. The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: contrasts with the effects of extinction. Pharmacology, Biochemistry, and Behavior. 50: 437-43. PMID 7617683 DOI: 10.1016/0091-3057(94)00294-S  0.477
1994 Sokolowski JD, McCullough LD, Salamone JD. Effects of dopamine depletions in the medial prefrontal cortex on active avoidance and escape in the rat. Brain Research. 651: 293-9. PMID 7922578 DOI: 10.1016/0006-8993(94)90709-9  0.46
1994 Salamone JD, Cousins MS, McCullough LD, Carriero DL, Berkowitz RJ. Nucleus accumbens dopamine release increases during instrumental lever pressing for food but not free food consumption. Pharmacology, Biochemistry, and Behavior. 49: 25-31. PMID 7816884 DOI: 10.1016/0091-3057(94)90452-9  0.485
1993 McCullough LD, Sokolowski JD, Salamone JD. A neurochemical and behavioral investigation of the involvement of nucleus accumbens dopamine in instrumental avoidance. Neuroscience. 52: 919-25. PMID 8450978 DOI: 10.1016/0306-4522(93)90538-Q  0.467
1993 Salamone JD, Kurth PA, McCullough LD, Sokolowski JD, Cousins MS. The role of brain dopamine in response initiation: effects of haloperidol and regionally specific dopamine depletions on the local rate of instrumental responding. Brain Research. 628: 218-26. PMID 8313150 DOI: 10.1016/0006-8993(93)90958-P  0.476
1993 McCullough LD, Cousins MS, Salamone JD. The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: a neurochemical and behavioral study. Pharmacology, Biochemistry, and Behavior. 46: 581-6. PMID 8278435 DOI: 10.1016/0091-3057(93)90547-7  0.487
1992 McCullough LD, Salamone JD. Increases in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens. Brain Research. 577: 1-9. PMID 1521135 DOI: 10.1016/0006-8993(92)90530-M  0.479
1992 McCullough LD, Salamone JD. Involvement of nucleus accumbens dopamine in the motor activity induced by periodic food presentation: a microdialysis and behavioral study. Brain Research. 592: 29-36. PMID 1450917 DOI: 10.1016/0006-8993(92)91654-W  0.496
1992 McCullough LD, Salamone JD. Anxiogenic drugs beta-CCE and FG 7142 increase extracellular dopamine levels in nucleus accumbens. Psychopharmacology. 109: 379-82. PMID 1365640 DOI: 10.1007/Bf02245888  0.465
1991 Salamone JD, Steinpreis RE, McCullough LD, Smith P, Grebel D, Mahan K. Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food choice procedure. Psychopharmacology. 104: 515-21. PMID 1780422 DOI: 10.1007/Bf02245659  0.69
1990 Salamone JD, Johnson CJ, McCullough LD, Steinpreis RE. Lateral striatal cholinergic mechanisms involved in oral motor activities in the rat. Psychopharmacology. 102: 529-34. PMID 2096410 DOI: 10.1007/Bf02247136  0.699
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