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Hans Hengartner - Publications

Affiliations: 
Institute for Experimental Immunology, Univ Zurich, Zürich, Zürich, Switzerland 
Area:
Immunology
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342 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, ... ... Hengartner H, et al. Reactive oxygen species delay control of lymphocytic choriomeningitis virus. Cell Death and Differentiation. 20: 649-58. PMID 23328631 DOI: 10.1038/Cdd.2012.167  0.654
2011 Igonet S, Vaney MC, Vonrhein C, Vonhrein C, Bricogne G, Stura EA, Hengartner H, Eschli B, Rey FA. X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19967-72. PMID 22123988 DOI: 10.1073/Pnas.1108910108  0.343
2011 Verschoor A, Neuenhahn M, Navarini AA, Graef P, Plaumann A, Seidlmeier A, Nieswandt B, Massberg S, Zinkernagel RM, Hengartner H, Busch DH. A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3. Nature Immunology. 12: 1194-201. PMID 22037602 DOI: 10.1038/ni.2140  0.54
2010 Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, et al. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (Baltimore, Md.). 52: 25-32. PMID 20578253 DOI: 10.1002/Hep.23640  0.617
2010 Navarini AA, Krzyzowska M, Lang KS, Horvath E, Hengartner H, Niemialtowski MG, Zinkernagel RM. Long-lasting immunity by early infection of maternal-antibody-protected infants. European Journal of Immunology. 40: 113-6. PMID 19877011 DOI: 10.1002/eji.200939371  0.54
2009 Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections. Proceedings of the National Academy of Sciences of the United States of America. 106: 7107-12. PMID 19351895 DOI: 10.1073/Pnas.0901162106  0.504
2009 Geuking MB, Weber J, Dewannieux M, Gorelik E, Heidmann T, Hengartner H, Zinkernagel RM, Hangartner L. Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration. Science (New York, N.Y.). 323: 393-6. PMID 19150848 DOI: 10.1126/science.1167375  0.485
2008 McCoy KD, Stoel M, Stettler R, Merky P, Fink K, Senn BM, Schaer C, Massacand J, Odermatt B, Oettgen HC, Zinkernagel RM, Bos NA, Hengartner H, Macpherson AJ, Harris NL. Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection. Cell Host & Microbe. 4: 362-73. PMID 18854240 DOI: 10.1016/j.chom.2008.08.014  0.568
2008 Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, ... ... Hengartner H, et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nature Medicine. 14: 756-61. PMID 18516052 DOI: 10.1038/Nm1780  0.577
2008 Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. The Journal of Experimental Medicine. 205: 53-61. PMID 18195073 DOI: 10.1084/Jem.20071855  0.631
2008 Fink K, Zellweger R, Weber J, Manjarrez-Orduno N, Holdener M, Senn BM, Hengartner H, Zinkernagel RM, Macpherson AJ. Long-term maternal imprinting of the specific B cell repertoire by maternal antibodies. European Journal of Immunology. 38: 90-101. PMID 18081043 DOI: 10.1002/eji.200737872  0.59
2007 Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M. "Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses. Plos One. 2: e1162. PMID 18000535 DOI: 10.1371/Journal.Pone.0001162  0.663
2007 Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, ... ... Hengartner H, et al. Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. Nature Medicine. 13: 1316-23. PMID 17982463 DOI: 10.1038/Nm1670  0.687
2007 Fink K, Manjarrez-Orduño N, Schildknecht A, Weber J, Senn BM, Zinkernagel RM, Hengartner H. B cell activation state-governed formation of germinal centers following viral infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 5877-85. PMID 17947661 DOI: 10.4049/Jimmunol.179.9.5877  0.62
2007 Eschli B, Zellweger RM, Wepf A, Lang KS, Quirin K, Weber J, Zinkernagel RM, Hengartner H. Early antibodies specific for the neutralizing epitope on the receptor binding subunit of the lymphocytic choriomeningitis virus glycoprotein fail to neutralize the virus. Journal of Virology. 81: 11650-7. PMID 17699567 DOI: 10.1128/JVI.00955-07  0.608
2007 Freigang S, Eschli B, Harris N, Geuking M, Quirin K, Schrempf S, Zellweger R, Weber J, Hengartner H, Zinkernagel RM. A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses. Proceedings of the National Academy of Sciences of the United States of America. 104: 13426-31. PMID 17686978 DOI: 10.1073/pnas.0704423104  0.633
2007 Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM. MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus. European Journal of Immunology. 37: 2434-40. PMID 17668900 DOI: 10.1002/Eji.200737310  0.58
2007 Pochanke V, Koller S, Dayer R, Hatak S, Ludewig B, Zinkernagel RM, Hengartner H, McCoy KD. Identification and characterization of a novel antigen from the nematode Nippostrongylus brasiliensis recognized by specific IgE. European Journal of Immunology. 37: 1275-84. PMID 17429848 DOI: 10.1002/eji.200737135  0.577
2007 Scandella E, Fink K, Junt T, Senn BM, Lattmann E, Förster R, Hengartner H, Ludewig B. Dendritic cell-independent B cell activation during acute virus infection: a role for early CCR7-driven B-T helper cell collaboration. Journal of Immunology (Baltimore, Md. : 1950). 178: 1468-76. PMID 17237395 DOI: 10.4049/Jimmunol.178.3.1468  0.508
2006 Zellweger RM, Hangartner L, Weber J, Zinkernagel RM, Hengartner H. Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection. European Journal of Immunology. 36: 3175-85. PMID 17125146 DOI: 10.1002/eji.200636087  0.64
2006 Navarini AA, Recher M, Lang KS, Georgiev P, Meury S, Bergthaler A, Flatz L, Bille J, Landmann R, Odermatt B, Hengartner H, Zinkernagel RM. Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 15535-9. PMID 17030789 DOI: 10.1073/pnas.0607325103  0.549
2006 Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM. Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC. Proceedings of the National Academy of Sciences of the United States of America. 103: 14435-40. PMID 16983067 DOI: 10.1073/pnas.0606707103  0.635
2006 Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM. Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling. The Journal of Clinical Investigation. 116: 2456-63. PMID 16955143 DOI: 10.1172/JCI28349  0.553
2006 Pochanke V, Hatak S, Hengartner H, Zinkernagel RM, McCoy KD. Induction of IgE and allergic-type responses in fur mite-infested mice. European Journal of Immunology. 36: 2434-45. PMID 16909433 DOI: 10.1002/eji.200635949  0.583
2006 Hangartner L, Zellweger RM, Giobbi M, Weber J, Eschli B, McCoy KD, Harris N, Recher M, Zinkernagel RM, Hengartner H. Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread. The Journal of Experimental Medicine. 203: 2033-42. PMID 16880253 DOI: 10.1084/jem.20051557  0.59
2006 Zinkernagel RM, Hengartner H. Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'. Immunological Reviews. 211: 310-9. PMID 16824138 DOI: 10.1111/j.0105-2896.2006.00402.x  0.616
2006 Fink K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, Hengartner H. Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses. European Journal of Immunology. 36: 2094-105. PMID 16810635 DOI: 10.1002/eji.200635993  0.619
2006 Eschli B, Quirin K, Wepf A, Weber J, Zinkernagel R, Hengartner H. Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins. Journal of Virology. 80: 5897-907. PMID 16731928 DOI: 10.1128/JVI.00008-06  0.487
2006 McCoy KD, Harris NL, Diener P, Hatak S, Odermatt B, Hangartner L, Senn BM, Marsland BJ, Geuking MB, Hengartner H, Macpherson AJ, Zinkernagel RM. Natural IgE production in the absence of MHC Class II cognate help. Immunity. 24: 329-39. PMID 16546101 DOI: 10.1016/j.immuni.2006.01.013  0.614
2006 Hangartner L, Zinkernagel RM, Hengartner H. Antiviral antibody responses: the two extremes of a wide spectrum. Nature Reviews. Immunology. 6: 231-43. PMID 16498452 DOI: 10.1038/nri1783  0.588
2006 Bonilla WV, Geuking MB, Aichele P, Ludewig B, Hengartner H, Zinkernagel RM. Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire. The Journal of Clinical Investigation. 116: 156-62. PMID 16395404 DOI: 10.1172/JCI26565  0.618
2006 Zinkernagel RM, Hengartner H. Infections, Immunity, and Autoimmunity The Autoimmune Diseases. 289-295. DOI: 10.1016/B978-012595961-2/50025-1  0.468
2005 Junt T, Fink K, Förster R, Senn B, Lipp M, Muramatsu M, Zinkernagel RM, Ludewig B, Hengartner H. CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses. Journal of Immunology (Baltimore, Md. : 1950). 175: 7109-16. PMID 16301613 DOI: 10.4049/Jimmunol.175.11.7109  0.605
2005 Lang KS, Recher M, Navarini AA, Freigang S, Harris NL, van den Broek M, Odermatt B, Hengartner H, Zinkernagel RM. Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology. Journal of Immunology (Baltimore, Md. : 1950). 175: 5524-31. PMID 16210661 DOI: 10.4049/Jimmunol.175.8.5524  0.598
2005 Zinkernagel R, Hengartner H. Responses to Cohn's discussion on the Zinkernagel-Hengartner 'Credo 2004'. Scandinavian Journal of Immunology. 62: 195-201. PMID 16179005 DOI: 10.1111/j.1365-3083.2005.01628.x  0.432
2005 Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM. Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation. European Journal of Immunology. 35: 738-45. PMID 15724249 DOI: 10.1002/eji.200425828  0.65
2005 Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nature Medicine. 11: 138-45. PMID 15654326 DOI: 10.1038/nm1176  0.625
2005 Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Erratum: Corrigendum: Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease Nature Medicine. 11: 1256-1256. DOI: 10.1038/NM1105-1256  0.56
2004 Junt T, Scandella E, Förster R, Krebs P, Krautwald S, Lipp M, Hengartner H, Ludewig B. Impact of CCR7 on priming and distribution of antiviral effector and memory CTL. Journal of Immunology (Baltimore, Md. : 1950). 173: 6684-93. PMID 15557160 DOI: 10.4049/Jimmunol.173.11.6684  0.557
2004 Pinschewer DD, Perez M, Jeetendra E, Bächi T, Horvath E, Hengartner H, Whitt MA, de la Torre JC, Zinkernagel RM. Kinetics of protective antibodies are determined by the viral surface antigen. The Journal of Clinical Investigation. 114: 988-93. PMID 15467838 DOI: 10.1172/Jci200422374  0.605
2004 Recher M, Lang KS, Hunziker L, Freigang S, Eschli B, Harris NL, Navarini A, Senn BM, Fink K, Lötscher M, Hangartner L, Zellweger R, Hersberger M, Theocharides A, Hengartner H, et al. Deliberate removal of T cell help improves virus-neutralizing antibody production. Nature Immunology. 5: 934-42. PMID 15300247 DOI: 10.1038/ni1102  0.692
2004 Zinkernagel RM, Hengartner H. On immunity against infections and vaccines: credo 2004. Scandinavian Journal of Immunology. 60: 9-13. PMID 15238068 DOI: 10.1111/j.0300-9475.2004.01460.x  0.616
2004 Martinic MM, Rocha B, McCoy KD, Hengartner H, Zinkernagel RM. Role of TCR-restricting MHC density and thymic environment on selection and survival of cells expressing low-affinity T cell receptors. European Journal of Immunology. 34: 1041-9. PMID 15048714 DOI: 10.1002/eji.200424920  0.553
2003 Planz O, Seiler P, Hengartner H, Zinkernagel RM. Specific cytotoxic T cells eliminate cells producing neutralizing antibodies. Nature. 426: 474. PMID 14647387 DOI: 10.1038/nature02146  0.66
2003 Freigang S, Egger D, Bienz K, Hengartner H, Zinkernagel RM. Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming. Proceedings of the National Academy of Sciences of the United States of America. 100: 13477-82. PMID 14595029 DOI: 10.1073/pnas.1835685100  0.631
2003 Hangartner L, Senn BM, Ledermann B, Kalinke U, Seiler P, Bucher E, Zellweger RM, Fink K, Odermatt B, Bürki K, Zinkernagel RM, Hengartner H. Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies. Proceedings of the National Academy of Sciences of the United States of America. 100: 12883-8. PMID 14569006 DOI: 10.1073/Pnas.2135542100  0.665
2003 Silverstein AM, Rose NR, Hunziker L, Recher M, Macpherson AJ, Hengartner H, Zinkernagel RM. On the implications of polyclonal B cell activation (multiple letters) Nature Immunology. 4: 931-932. PMID 14515119 DOI: 10.1038/Ni1003-931  0.452
2003 Hunziker L, Ciurea A, Recher M, Hengartner H, Zinkernagel RM. Public versus personal serotypes of a viral quasispecies. Proceedings of the National Academy of Sciences of the United States of America. 100: 6015-20. PMID 12730366 DOI: 10.1073/pnas.1031671100  0.594
2003 Senn BM, López-Macías C, Kalinke U, Lamarre A, Isibasi A, Zinkernagel RM, Hengartner H. Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections. European Journal of Immunology. 33: 950-61. PMID 12672061 DOI: 10.1002/eji.200323340  0.639
2003 Hunziker L, Recher M, Macpherson AJ, Ciurea A, Freigang S, Hengartner H, Zinkernagel RM. Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections. Nature Immunology. 4: 343-9. PMID 12627229 DOI: 10.1038/ni911  0.685
2003 Martinic MM, Rülicke T, Althage A, Odermatt B, Höchli M, Lamarre A, Dumrese T, Speiser DE, Kyburz D, Hengartner H, Zinkernagel RM. Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC. Proceedings of the National Academy of Sciences of the United States of America. 100: 1861-6. PMID 12574503 DOI: 10.1073/pnas.252641399  0.669
2003 Hunziker L, Recher M, Macpherson AJ, Hengartner H, Zinkernagel RM. Reply to 'On the implications of polyclonal B cell activation' Nature Immunology. 4: 932-932. DOI: 10.1038/NI1003-932  0.519
2002 Hunziker L, Recher M, Ciurea A, Martinic MM, Odermatt B, Hengartner H, Zinkernagel RM. Antagonistic variant virus prevents wild-type virus-induced lethal immunopathology. The Journal of Experimental Medicine. 196: 1039-46. PMID 12391015 DOI: 10.1084/jem.20012045  0.667
2002 Oehen S, Odermatt B, Karrer U, Hengartner H, Zinkernagel R, López-Macías C. Marginal zone macrophages and immune responses against viruses. Journal of Immunology (Baltimore, Md. : 1950). 169: 1453-8. PMID 12133971 DOI: 10.4049/Jimmunol.169.3.1453  0.58
2002 Pan Q, Matamoros N, Björkander J, Conley ME, Hammarström L, Macpherson AJ, Lamarre A, Hengartner H, Zinkernagel RM. Lack of IgA in Cμ-deficient patients (multiple letters) Nature Immunology. 3: 595-596. PMID 12087410 DOI: 10.1038/ni0702-595  0.356
2002 Ludewig B, Zinkernagel RM, Hengartner H. Arterial inflammation and atherosclerosis. Trends in Cardiovascular Medicine. 12: 154-9. PMID 12069754 DOI: 10.1016/S1050-1738(01)00166-9  0.486
2002 Pericin M, Althage A, Freigang S, Hengartner H, Rolland E, Dupraz P, Thorens B, Aebischer P, Zinkernagel RM. Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proceedings of the National Academy of Sciences of the United States of America. 99: 8203-6. PMID 12060765 DOI: 10.1073/pnas.122241299  0.519
2002 Junt T, Nakano H, Dumrese T, Kakiuchi T, Odermatt B, Zinkernagel RM, Hengartner H, Ludewig B. Antiviral immune responses in the absence of organized lymphoid T cell zones in plt/plt mice. Journal of Immunology (Baltimore, Md. : 1950). 168: 6032-40. PMID 12055211 DOI: 10.4049/Jimmunol.168.12.6032  0.678
2002 Bonilla WV, Pinschewer DD, Klenerman P, Rousson V, Gaboli M, Pandolfi PP, Zinkernagel RM, Salvato MS, Hengartner H. Effects of promyelocytic leukemia protein on virus-host balance. Journal of Virology. 76: 3810-8. PMID 11907221 DOI: 10.1128/Jvi.76.8.3810-3818.2002  0.649
2002 Macpherson AJ, Lamarre A, Hengartner H, Zinkernagel RM. Response to 'Lack of IgA in Cμ-deficient patients' Nature Immunology. 3: 596-596. DOI: 10.1038/ni0702-596  0.459
2001 Zinkernagel RM, LaMarre A, Ciurea A, Hunziker L, Ochsenbein AF, McCoy KD, Fehr T, Bachmann MF, Kalinke U, Hengartner H. Neutralizing antiviral antibody responses. Advances in Immunology. 79: 1-53. PMID 11680006 DOI: 10.1016/S0065-2776(01)79001-3  0.608
2001 Ludewig B, Junt T, Hengartner H, Zinkernagel RM. Dendritic cells in autoimmune diseases. Current Opinion in Immunology. 13: 657-62. PMID 11677086 DOI: 10.1016/S0952-7915(01)00275-8  0.559
2001 Zinkernagel RM, Hengartner H. Regulation of the immune response by antigen. Science (New York, N.Y.). 293: 251-3. PMID 11452115 DOI: 10.1126/science.1063005  0.593
2001 Ciurea A, Hunziker L, Martinic MM, Oxenius A, Hengartner H, Zinkernagel RM. CD4+ T-cell-epitope escape mutant virus selected in vivo. Nature Medicine. 7: 795-800. PMID 11433343 DOI: 10.1038/89915  0.675
2001 Ochsenbein AF, Sierro S, Odermatt B, Pericin M, Karrer U, Hermans J, Hemmi S, Hengartner H, Zinkernagel RM. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature. 411: 1058-64. PMID 11429607 DOI: 10.1038/35082583  0.629
2001 Macpherson AJ, Lamarre A, McCoy K, Harriman GR, Odermatt B, Dougan G, Hengartner H, Zinkernagel RM. IgA production without mu or delta chain expression in developing B cells. Nature Immunology. 2: 625-31. PMID 11429547 DOI: 10.1038/89775  0.587
2001 Ciurea A, Hunziker L, Zinkernagel RM, Hengartner H. Viral escape from the neutralizing antibody response: the lymphocytic choriomeningitis virus model. Immunogenetics. 53: 185-9. PMID 11398962 DOI: 10.1007/s002510100314  0.626
2001 Ludewig B, Bonilla WV, Dumrese T, Odermatt B, Zinkernagel RM, Hengartner H. Perforin-independent regulation of dendritic cell homeostasis by CD8(+) T cells in vivo: implications for adaptive immunotherapy. European Journal of Immunology. 31: 1772-9. PMID 11385622 DOI: 10.1002/1521-4141(200106)31:6<1772::AID-IMMU1772>3.0.CO;2-8  0.603
2001 Ludewig B, McCoy K, Pericin M, Ochsenbein AF, Dumrese T, Odermatt B, Toes RE, Melief CJ, Hengartner H, Zinkernagel RM. Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 3678-87. PMID 11238607 DOI: 10.4049/Jimmunol.166.6.3678  0.518
2001 Ludewig B, Jäggi M, Dumrese T, Brduscha-Riem K, Odermatt B, Hengartner H, Zinkernagel RM. Hypercholesterolemia exacerbates virus-induced immunopathologic liver disease via suppression of antiviral cytotoxic T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 166: 3369-76. PMID 11207293 DOI: 10.4049/Jimmunol.166.5.3369  0.627
2001 Ciurea A, Hunziker L, Klenerman P, Hengartner H, Zinkernagel RM. Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants. The Journal of Experimental Medicine. 193: 297-305. PMID 11157050 DOI: 10.1084/jem.193.3.297  0.658
2000 Moretta L, Moretta A, Hengartner H, Zinkernagel RM. On the pathogenesis of perforin defects and related immunodeficiencies. Immunology Today. 21: 593-4. PMID 11221685 DOI: 10.1016/S0167-5699(00)01731-X  0.607
2000 van den Broek MF, Hengartner H. The role of perforin in infections and tumour surveillance. Experimental Physiology. 85: 681-5. PMID 11187963 DOI: 10.1111/J.1469-445X.2000.02097.X  0.473
2000 Ludewig B, Zinkernagel RM, Hengartner H. Transgenic animal models for virus-induced autoimmune diseases. Experimental Physiology. 85: 653-9. PMID 11187961 DOI: 10.1111/J.1469-445X.2000.02093.X  0.601
2000 Ochsenbein AF, Pinschewer DD, Sierro S, Horvath E, Hengartner H, Zinkernagel RM. Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs. Proceedings of the National Academy of Sciences of the United States of America. 97: 13263-8. PMID 11069289 DOI: 10.1073/pnas.230417497  0.602
2000 Karrer U, Althage A, Odermatt B, Hengartner H, Zinkernagel RM. Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect. European Journal of Immunology. 30: 2799-807. PMID 11069060 DOI: 10.1002/1521-4141(200010)30:10<2799::AID-IMMU2799>3.0.CO;2-2  0.63
2000 Ludewig B, Freigang S, Jäggi M, Kurrer MO, Pei YC, Vlk L, Odermatt B, Zinkernagel RM, Hengartner H. Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 97: 12752-7. PMID 11050173 DOI: 10.1073/pnas.220427097  0.525
2000 Klenerman P, Lechner F, Kantzanou M, Ciurea A, Hengartner H, Zinkernagel R. Viral escape and the failure of cellular immune responses. Science (New York, N.Y.). 289: 2003. PMID 11032545 DOI: 10.1126/SCIENCE.289.5487.2003A  0.52
2000 Fehr T, López-Macías C, Odermatt B, Torres RM, Schubart DB, O'Keefe TL, Matthias P, Hengartner H, Zinkernagel RM. Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules. International Immunology. 12: 1275-84. PMID 10967022 DOI: 10.1093/INTIMM/12.9.1275  0.677
2000 Kalinke U, Oxenius A, Lopez-Macias C, Zinkernagel RM, Hengartner H. Virus neutralization by germ-line vs. hypermutated antibodies. Proceedings of the National Academy of Sciences of the United States of America. 97: 10126-31. PMID 10963674 DOI: 10.1073/Pnas.97.18.10126  0.563
2000 Ludewig B, Barchiesi F, Pericin M, Zinkernagel RM, Hengartner H, Schwendener RA. In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity. Vaccine. 19: 23-32. PMID 10924783 DOI: 10.1016/S0264-410X(00)00163-8  0.565
2000 Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM. A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science (New York, N.Y.). 288: 2222-6. PMID 10864873 DOI: 10.1126/science.288.5474.2222  0.595
2000 Maloy KJ, Burkhart C, Junt TM, Odermatt B, Oxenius A, Piali L, Zinkernagel RM, Hengartner H. CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability. The Journal of Experimental Medicine. 191: 2159-70. PMID 10859340 DOI: 10.1084/jem.191.12.2159  0.65
2000 Seiler P, Senn BM, Klenerman P, Kalinke U, Hengartner H, Zinkernagel RM. Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence. Journal of Virology. 74: 5896-901. PMID 10846070 DOI: 10.1128/JVI.74.13.5896-5901.2000  0.6
2000 Ochsenbein AF, Pinschewer DD, Odermatt B, Ciurea A, Hengartner H, Zinkernagel RM. Correlation of T cell independence of antibody responses with antigen dose reaching secondary lymphoid organs: implications for splenectomized patients and vaccine design. Journal of Immunology (Baltimore, Md. : 1950). 164: 6296-302. PMID 10843683 DOI: 10.4049/Jimmunol.164.12.6296  0.619
2000 Barchet W, Oehen S, Klenerman P, Wodarz D, Bocharov G, Lloyd AL, Nowak MA, Hengartner H, Zinkernagel RM, Ehl S. Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo. European Journal of Immunology. 30: 1356-63. PMID 10820382 DOI: 10.1002/(Sici)1521-4141(200005)30:5<1356::Aid-Immu1356>3.0.Co;2-K  0.676
2000 Pinschewer DD, Ochsenbein AF, Odermatt B, Brinkmann V, Hengartner H, Zinkernagel RM. FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory. Journal of Immunology (Baltimore, Md. : 1950). 164: 5761-70. PMID 10820254 DOI: 10.4049/Jimmunol.164.11.5761  0.683
2000 Ehl S, Barchet W, Oehen S, Aichele P, Hombach J, Hengartner H, Zinkernagel RM. Donor cell persistence and activation-induced unresponsiveness of peripheral CD8+ T cells. European Journal of Immunology. 30: 883-91. PMID 10741405 DOI: 10.1002/1521-4141(200003)30:3<883::AID-IMMU883>3.0.CO;2-U  0.676
2000 Ludewig B, Ochsenbein AF, Odermatt B, Paulin D, Hengartner H, Zinkernagel RM. Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease. The Journal of Experimental Medicine. 191: 795-804. PMID 10704461 DOI: 10.1084/jem.191.5.795  0.553
2000 Ciurea A, Klenerman P, Hunziker L, Horvath E, Senn BM, Ochsenbein AF, Hengartner H, Zinkernagel RM. Viral persistence in vivo through selection of neutralizing antibody-escape variants. Proceedings of the National Academy of Sciences of the United States of America. 97: 2749-54. PMID 10688894 DOI: 10.1073/pnas.040558797  0.632
2000 Karrer U, López-Macías C, Oxenius A, Odermatt B, Bachmann MF, Kalinke U, Bluethmann H, Hengartner H, Zinkernagel RM. Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 164: 768-78. PMID 10623822 DOI: 10.4049/Jimmunol.164.2.768  0.601
2000 Ludewig B, Maloy KJ, López-Macías C, Odermatt B, Hengartner H, Zinkernagel RM. Induction of optimal anti-viral neutralizing B cell responses by dendritic cells requires transport and release of virus particles in secondary lymphoid organs. European Journal of Immunology. 30: 185-96. PMID 10602040 DOI: 10.1002/1521-4141(200001)30:1<185::AID-IMMU185>3.0.CO;2-L  0.651
1999 Ochsenbein AF, Fehr T, Lutz C, Suter M, Brombacher F, Hengartner H, Zinkernagel RM. Control of early viral and bacterial distribution and disease by natural antibodies. Science (New York, N.Y.). 286: 2156-9. PMID 10591647 DOI: 10.1126/science.286.5447.2156  0.583
1999 Ochsenbein AF, Pinschewer DD, Odermatt B, Carroll MC, Hengartner H, Zinkernagel RM. Protective T cell-independent antiviral antibody responses are dependent on complement. The Journal of Experimental Medicine. 190: 1165-74. PMID 10523614 DOI: 10.1084/jem.190.8.1165  0.672
1999 Ciurea A, Klenerman P, Hunziker L, Horvath E, Odermatt B, Ochsenbein AF, Hengartner H, Zinkernagel RM. Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 11964-9. PMID 10518559 DOI: 10.1073/pnas.96.21.11964  0.63
1999 Pinschewer DD, Ochsenbein AF, Satterthwaite AB, Witte ON, Hengartner H, Zinkernagel RM. A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion. European Journal of Immunology. 29: 2981-7. PMID 10508272 DOI: 10.1002/(SICI)1521-4141(199909)29:09<2981::AID-IMMU2981>3.0.CO;2-Y  0.622
1999 Ludewig B, Odermatt B, Ochsenbein AF, Zinkernagel RM, Hengartner H. Role of dendritic cells in the induction and maintenance of autoimmune diseases. Immunological Reviews. 169: 45-54. PMID 10450507 DOI: 10.1111/j.1600-065X.1999.tb01305.x  0.527
1999 Ludewig B, Oehen S, Barchiesi F, Schwendener RA, Hengartner H, Zinkernagel RM. Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 163: 1839-44. PMID 10438917 DOI: 10.5167/Uzh-19974  0.625
1999 Ochsenbein AF, Karrer U, Klenerman P, Althage A, Ciurea A, Shen H, Miller JF, Whitton JL, Hengartner H, Zinkernagel RM. A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria. Proceedings of the National Academy of Sciences of the United States of America. 96: 9293-8. PMID 10430936 DOI: 10.1073/Pnas.96.16.9293  0.64
1999 Zinkernagel RM, Planz O, Ehl S, Battegay M, Odermatt B, Klenerman P, Hengartner H. General and specific immunosuppression caused by antiviral T-cell responses. Immunological Reviews. 168: 305-15. PMID 10399082 DOI: 10.1111/j.1600-065X.1999.tb01300.x  0.706
1999 López-Macías C, Kalinke U, Cascalho M, Wabl M, Hengartner H, Zinkernagel RM, Lamarre A. Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses. The Journal of Experimental Medicine. 189: 1791-8. PMID 10359583 DOI: 10.1084/jem.189.11.1791  0.644
1999 Seiler P, Senn BM, Bründler MA, Zinkernagel RM, Hengartner H, Kalinke U. In vivo selection of neutralization-resistant virus variants but no evidence of B cell tolerance in lymphocytic choriomeningitis virus carrier mice expressing a transgenic virus-neutralizing antibody. Journal of Immunology (Baltimore, Md. : 1950). 162: 4536-41. PMID 10201992  0.584
1999 Oxenius A, Martinic MM, Hengartner H, Klenerman P. CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines. Journal of Virology. 73: 4120-6. PMID 10196308 DOI: 10.1128/Jvi.73.5.4120-4126.1999  0.556
1999 Maloy KJ, Burkhart C, Freer G, Rülicke T, Pircher H, Kono DH, Theofilopoulos AN, Ludewig B, Hoffmann-Rohrer U, Zinkernagel RM, Hengartner H. Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection. Journal of Immunology (Baltimore, Md. : 1950). 162: 2867-74. PMID 10072535  0.613
1999 Ochsenbein AF, Klenerman P, Karrer U, Ludewig B, Pericin M, Hengartner H, Zinkernagel RM. Immune surveillance against a solid tumor fails because of immunological ignorance. Proceedings of the National Academy of Sciences of the United States of America. 96: 2233-8. PMID 10051624 DOI: 10.1073/pnas.96.5.2233  0.567
1999 Steinhoff U, Maloy KJ, Burkhart C, Clark AJ, Rülicke T, Hengartner H, Zinkernagel RM. Variable immune response against a developmentally regulated self-antigen. Journal of Autoimmunity. 12: 27-34. PMID 10028019 DOI: 10.1006/jaut.1998.0254  0.617
1999 Oxenius A, Karrer U, Zinkernagel RM, Hengartner H. IL-12 is not required for induction of type 1 cytokine responses in viral infections. Journal of Immunology (Baltimore, Md. : 1950). 162: 965-73. PMID 9916721  0.562
1998 Williams GS, Oxenius A, Hengartner H, Benoist C, Mathis D. CD4+ T cell responses in mice lacking MHC class II molecules specifically on B cells. European Journal of Immunology. 28: 3763-72. PMID 9842919 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3763::Aid-Immu3763>3.0.Co;2-D  0.492
1998 Gallimore A, Schwarz K, van den Broek M, Hengartner H, Groettrup M. The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader-derived T cell epitope. Molecular Immunology. 35: 581-91. PMID 9823757 DOI: 10.1016/S0161-5890(98)00053-4  0.491
1998 Gallimore A, Hombach J, Dumrese T, Rammensee HG, Zinkernagel RM, Hengartner H. A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells. European Journal of Immunology. 28: 3301-11. PMID 9808199 DOI: 10.1002/(SICI)1521-4141(199810)28:10<3301::AID-IMMU3301>3.0.CO;2-Q  0.582
1998 Oxenius A, Zinkernagel RM, Hengartner H. Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection. Immunity. 9: 449-57. PMID 9806631 DOI: 10.1016/S1074-7613(00)80628-7  0.631
1998 Funk GA, Barbour AD, Hengartner H, Kalinke U. Mathematical model of a virus-neutralizing immunglobulin response. Journal of Theoretical Biology. 195: 41-52. PMID 9802949 DOI: 10.1006/jtbi.1998.0779  0.369
1998 Gallimore A, Hengartner H, Zinkernagel R. Hierarchies of antigen-specific cytotoxic T-cell responses. Immunological Reviews. 164: 29-36. PMID 9795761 DOI: 10.1111/j.1600-065X.1998.tb01205.x  0.66
1998 Ludewig B, Odermatt B, Landmann S, Hengartner H, Zinkernagel RM. Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. The Journal of Experimental Medicine. 188: 1493-501. PMID 9782126 DOI: 10.1084/jem.188.8.1493  0.627
1998 Oxenius A, Zinkernagel RM, Hengartner H. CD4+ T-cell induction and effector functions: a comparison of immunity against soluble antigens and viral infections. Advances in Immunology. 70: 313-67. PMID 9755341 DOI: 10.1016/S0065-2776(08)60390-9  0.67
1998 Ehl S, Aichele P, Ramseier H, Barchet W, Hombach J, Pircher H, Hengartner H, Zinkernagel RM. Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection. Nature Medicine. 4: 1015-9. PMID 9734393 DOI: 10.1038/2001  0.569
1998 Fehr T, Naim HY, Bachmann MF, Ochsenbein AF, Spielhofer P, Bucher E, Hengartner H, Billeter MA, Zinkernagel RM. T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses. Nature Medicine. 4: 945-8. PMID 9701248 DOI: 10.1038/nm0898-945  0.686
1998 Fehr T, Rickert RC, Odermatt B, Roes J, Rajewsky K, Hengartner H, Zinkernagel RM. Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19. The Journal of Experimental Medicine. 188: 145-55. PMID 9653091 DOI: 10.1084/Jem.188.1.145  0.611
1998 Binder D, van den Broek MF, Kägi D, Bluethmann H, Fehr J, Hengartner H, Zinkernagel RM. Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus. The Journal of Experimental Medicine. 187: 1903-20. PMID 9607930 DOI: 10.1084/jem.187.11.1903  0.686
1998 Van den Broek MF, Kägi D, Hengartner H. Effector pathways of natural killer cells. Current Topics in Microbiology and Immunology. 230: 123-31. PMID 9586354 DOI: 10.1007/978-3-642-46859-9_9  0.415
1998 Gallimore A, Dumrese T, Hengartner H, Zinkernagel RM, Rammensee HG. Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. The Journal of Experimental Medicine. 187: 1647-57. PMID 9584143 DOI: 10.1084/jem.187.10.1647  0.635
1998 Gallimore A, Glithero A, Godkin A, Tissot AC, Plückthun A, Elliott T, Hengartner H, Zinkernagel R. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. The Journal of Experimental Medicine. 187: 1383-93. PMID 9565631 DOI: 10.1084/Jem.187.9.1383  0.68
1998 Ludewig B, Ehl S, Karrer U, Odermatt B, Hengartner H, Zinkernagel RM. Dendritic cells efficiently induce protective antiviral immunity. Journal of Virology. 72: 3812-8. PMID 9557664 DOI: 10.1128/Jvi.72.5.3812-3818.1998  0.613
1998 Seiler P, Kalinke U, Rülicke T, Bucher EM, Böse C, Zinkernagel RM, Hengartner H. Enhanced virus clearance by early inducible lymphocytic choriomeningitis virus-neutralizing antibodies in immunoglobulin-transgenic mice. Journal of Virology. 72: 2253-8. PMID 9499083 DOI: 10.1128/Jvi.72.3.2253-2258.1998  0.607
1998 Oxenius A, Bachmann MF, Zinkernagel RM, Hengartner H. Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection. European Journal of Immunology. 28: 390-400. PMID 9485218 DOI: 10.1002/(SICI)1521-4141(199801)28:01<390::AID-IMMU390>3.0.CO;2-O  0.704
1998 Ehl S, Hombach J, Aichele P, Rülicke T, Odermatt B, Hengartner H, Zinkernagel R, Pircher H. Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology. The Journal of Experimental Medicine. 187: 763-74. PMID 9480986 DOI: 10.1084/jem.187.5.763  0.677
1998 Seiler P, Bründler MA, Zimmermann C, Weibel D, Bruns M, Hengartner H, Zinkernagel RM. Induction of protective cytotoxic T cell responses in the presence of high titers of virus-neutralizing antibodies: implications for passive and active immunization. The Journal of Experimental Medicine. 187: 649-54. PMID 9463415 DOI: 10.1084/jem.187.4.649  0.665
1998 Maloy KJ, Odermatt B, Hengartner H, Zinkernagel RM. Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 1160-5. PMID 9448302 DOI: 10.1073/pnas.95.3.1160  0.72
1997 Ehl S, Klenerman P, Aichele P, Hengartner H, Zinkernagel RM. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. European Journal of Immunology. 27: 3404-13. PMID 9464829 DOI: 10.1002/eji.1830271240  0.646
1997 Klenerman P, Hengartner H, Zinkernagel RM. A non-retroviral RNA virus persists in DNA form. Nature. 390: 298-301. PMID 9384383 DOI: 10.1038/36876  0.562
1997 Seiler P, Aichele P, Odermatt B, Hengartner H, Zinkernagel RM, Schwendener RA. Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection. European Journal of Immunology. 27: 2626-33. PMID 9368619 DOI: 10.1002/eji.1830271023  0.663
1997 Bachmann MF, Oxenius A, Speiser DE, Mariathasan S, Hengartner H, Zinkernagel RM, Ohashi PS. Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation. European Journal of Immunology. 27: 2195-203. PMID 9341759 DOI: 10.1002/Eji.1830270912  0.602
1997 Kägi D, Odermatt B, Seiler P, Zinkernagel RM, Mak TW, Hengartner H. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. The Journal of Experimental Medicine. 186: 989-97. PMID 9314549 DOI: 10.1084/jem.186.7.989  0.546
1997 van den Broek MF, Spörri R, Even C, Plagemann PG, Hänseler E, Hengartner H, Zinkernagel RM. Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 159: 1585-8. PMID 9257815 DOI: 10.1016/S0165-2478(97)86210-4  0.663
1997 Bachmann MF, Kalinke U, Althage A, Freer G, Burkhart C, Roost H, Aguet M, Hengartner H, Zinkernagel RM. The role of antibody concentration and avidity in antiviral protection. Science (New York, N.Y.). 276: 2024-7. PMID 9197261 DOI: 10.1126/Science.276.5321.2024  0.547
1997 Planz O, Ehl S, Furrer E, Horvath E, Bründler MA, Hengartner H, Zinkernagel RM. A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proceedings of the National Academy of Sciences of the United States of America. 94: 6874-9. PMID 9192659 DOI: 10.1073/pnas.94.13.6874  0.69
1997 Oxenius A, Bachmann MF, Mathis D, Benoist C, Zinkernagel RM, Hengartner H. Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 158: 5717-26. PMID 9190921  0.509
1997 Zinkernagel RM, Hengartner H. Antiviral immunity. Immunology Today. 18: 258-60. PMID 9190107 DOI: 10.1016/S0167-5699(97)80017-5  0.602
1997 Karrer U, Althage A, Odermatt B, Roberts CW, Korsmeyer SJ, Miyawaki S, Hengartner H, Zinkernagel RM. On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice. The Journal of Experimental Medicine. 185: 2157-70. PMID 9182687 DOI: 10.1084/jem.185.12.2157  0.667
1997 Zinkernagel RM, Ehl S, Aichele P, Oehen S, Kündig T, Hengartner H. Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity. Immunological Reviews. 156: 199-209. PMID 9176709 DOI: 10.1111/J.1600-065X.1997.Tb00969.X  0.624
1997 Aichele P, Brduscha-Riem K, Oehen S, Odermatt B, Zinkernagel RM, Hengartner H, Pircher H. Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity. 6: 519-29. PMID 9175830 DOI: 10.1016/S1074-7613(00)80340-4  0.635
1997 Bachmann MF, Fehr T, Freer G, Hengartner H, Zinkernagel RM. Correlation of tolerogenicity of a viral antigen with its immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 158: 5106-11. PMID 9164925  0.544
1997 Fehr T, Bachmann MF, Bucher E, Kalinke U, Di Padova FE, Lang AB, Hengartner H, Zinkernagel RM. Role of repetitive antigen patterns for induction of antibodies against antibodies. The Journal of Experimental Medicine. 185: 1785-92. PMID 9151704 DOI: 10.1084/jem.185.10.1785  0.578
1997 Sad S, Krishnan L, Bleackley RC, Kägi D, Hengartner H, Mosmann TR. Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity. European Journal of Immunology. 27: 914-22. PMID 9130644 DOI: 10.1002/Eji.1830270417  0.464
1997 Mosmann TR, Li L, Hengartner H, Kagi D, Fu W, Sad S. Differentiation and functions of T cell subsets. Ciba Foundation Symposium. 204: 148-54; discussion 1. PMID 9107418  0.363
1997 Ehl S, Hombach J, Aichele P, Hengartner H, Zinkernagel RM. Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model. The Journal of Experimental Medicine. 185: 1241-51. PMID 9104811 DOI: 10.1084/jem.185.7.1241  0.674
1997 Binder D, Fehr J, Hengartner H, Zinkernagel RM. Virus-induced transient bone marrow aplasia: major role of interferon-alpha/beta during acute infection with the noncytopathic lymphocytic choriomeningitis virus. The Journal of Experimental Medicine. 185: 517-30. PMID 9053452 DOI: 10.1084/jem.185.3.517  0.576
1997 Bachmann MF, Kündig TM, Hengartner H, Zinkernagel RM. Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"? Proceedings of the National Academy of Sciences of the United States of America. 94: 640-5. PMID 9012837 DOI: 10.1073/pnas.94.2.640  0.656
1997 Zinkernagel RM, Bachmann MF, Kündig TM, Hengartner H. Response from Zinkernagel et al Trends in Microbiology. 5: 260-261. DOI: 10.1016/S0966-842X(97)01074-3  0.41
1997 López-Macías C, Kalinke U, Fehr T, Bucher E, Zinkemagel RM, Hengartner H. Induction of T-cell dependent VSV neutralizing antibodies by a fusion protein comprising VSV-G and the human IgG1 Fc portion Immunology Letters. 56: 300. DOI: 10.1016/S0165-2478(97)86211-6  0.447
1997 Kalinke U, Oxenius A, Lopez-Macias C, Zinkermagel RM, Hengartner H. Protection against lethal vesicular stomatitis virus (VSV) infection by hypermutated versus germline antibodies Immunology Letters. 56: 300. DOI: 10.1016/S0165-2478(97)86209-8  0.434
1997 Seiler P, Senn B, Bründler M, Zinkernagel R, Hengartner H. No B cell tolerance, but generation of antibody escape mutants in vivo in anti-lymphocytic choriomeningitis virus specific antibody transgenic mice Immunology Letters. 56: 249. DOI: 10.1016/S0165-2478(97)85990-1  0.611
1997 Aichele P, Brduscha-Riem K, Oehen S, Zinkernagel R, Hengartner H, Pircher H. Peptide-antigen treatment of naive and memory CTL: Antigen-specific tolerization versus immunopathology Immunology Letters. 56: 34. DOI: 10.1016/S0165-2478(97)85130-9  0.52
1997 Seiler P, Kalinke U, Rülicke T, Bucher EM, Böse C, Zinkemagel RM, Hengartner H. Enhanced virus clearance and prevention of CTL exhaustion by early inducible lymphocytic choriomeningitis virus specific neutralizing antibodies Immunology Letters. 56: 26-27. DOI: 10.1016/S0165-2478(97)85101-2  0.449
1996 Zinkernagel RM, Hengartner H. Correlates of Protective Viruses Damaging to HIV Infection. Science (New York, N.Y.). 272: 1362a. PMID 17832186 DOI: 10.1126/science.272.5266.1362a  0.473
1996 Kalinke U, Bucher EM, Ernst B, Oxenius A, Roost HP, Geley S, Kofler R, Zinkernagel RM, Hengartner H. The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus. Immunity. 5: 639-52. PMID 8986722 DOI: 10.1016/S1074-7613(00)80277-0  0.585
1996 Ehl S, Nuesch R, Tanaka T, Myasaka M, Hengartner H, Zinkernagel R. A comparison of efficacy and specificity of three NK depleting antibodies. Journal of Immunological Methods. 199: 149-53. PMID 8982356 DOI: 10.1016/S0022-1759(96)00175-5  0.611
1996 Kalinke U, Krebber A, Krebber C, Bucher E, Plückthun A, Zinkernagel RM, Hengartner H. Monovalent single-chain Fv fragments and bivalent miniantibodies bound to vesicular stomatitis virus protect against lethal infection. European Journal of Immunology. 26: 2801-6. PMID 8977271 DOI: 10.1002/Eji.1830261202  0.619
1996 Ghelardi E, Burkhart C, Senesi S, Hengartner H, Freer G. Cloning of an unidentified T-cell receptor alpha chain gene from a vesicular stomatitis virus-specific helper T-cell clone. Immunology Letters. 53: 31-9. PMID 8946215 DOI: 10.1016/0165-2478(96)02611-9  0.347
1996 Aichele P, Bachmann MF, Hengartner H, Zinkernagel RM. Immunopathology or organ-specific autoimmunity as a consequence of virus infection. Immunological Reviews. 152: 21-45. PMID 8930666 DOI: 10.1111/J.1600-065X.1996.Tb00909.X  0.556
1996 van den Broek ME, Kägi D, Ossendorp F, Toes R, Vamvakas S, Lutz WK, Melief CJ, Zinkernagel RM, Hengartner H. Decreased tumor surveillance in perforin-deficient mice. The Journal of Experimental Medicine. 184: 1781-90. PMID 8920866 DOI: 10.1084/Jem.184.5.1781  0.571
1996 Kägi D, Hengartner H. Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. Current Opinion in Immunology. 8: 472-7. PMID 8794015 DOI: 10.1016/S0952-7915(96)80033-1  0.521
1996 Kündig TM, Bachmann MF, Oehen S, Hoffmann UW, Simard JJ, Kalberer CP, Pircher H, Ohashi PS, Hengartner H, Zinkernagel RM. On the role of antigen in maintaining cytotoxic T-cell memory. Proceedings of the National Academy of Sciences of the United States of America. 93: 9716-23. PMID 8790397 DOI: 10.1073/pnas.93.18.9716  0.66
1996 Ehl S, Hoffmann-Rohrer U, Nagata S, Hengartner H, Zinkernagel R. Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo. Journal of Immunology (Baltimore, Md. : 1950). 156: 2357-60. PMID 8786290  0.45
1996 Kündig TM, Bachmann MF, Ohashi PS, Pircher H, Hengartner H, Zinkernagel RM. On T cell memory: arguments for antigen dependence. Immunological Reviews. 150: 63-90. PMID 8782702 DOI: 10.1111/J.1600-065X.1996.Tb00696.X  0.619
1996 Planz O, Seiler P, Hengartner H, Zinkernagel RM. Specific cytotoxic T cells eliminate B cells producing virus-neutralizing antibodies [corrected]. Nature. 382: 726-9. PMID 8751445 DOI: 10.1038/382726a0  0.617
1996 Zinkernagel RM, Bachmann MF, Kündig TM, Oehen S, Pirchet H, Hengartner H. On immunological memory. Annual Review of Immunology. 14: 333-67. PMID 8717518 DOI: 10.1146/annurev.immunol.14.1.333  0.659
1996 Kägi D, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annual Review of Immunology. 14: 207-32. PMID 8717513 DOI: 10.1146/annurev.immunol.14.1.207  0.668
1996 Zinkernagel RM, Hengartner H. Correlates of protective viruses damaging to HIV infection. Science (New York, N.Y.). 272: 1362. PMID 8650554  0.401
1996 Bachmann MF, Odermatt B, Hengartner H, Zinkernagel RM. Induction of long-lived germinal centers associated with persisting antigen after viral infection. The Journal of Experimental Medicine. 183: 2259-69. PMID 8642335 DOI: 10.1084/jem.183.5.2259  0.666
1996 Oxenius A, Campbell KA, Maliszewski CR, Kishimoto T, Kikutani H, Hengartner H, Zinkernagel RM, Bachmann MF. CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions. The Journal of Experimental Medicine. 183: 2209-18. PMID 8642330 DOI: 10.1084/jem.183.5.2209  0.642
1996 Kägi D, Odermatt B, Ohashi PS, Zinkernagel RM, Hengartner H. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity. The Journal of Experimental Medicine. 183: 2143-52. PMID 8642324 DOI: 10.1084/jem.183.5.2143  0.651
1996 Fehr T, Bachmann MF, Bluethmann H, Kikutani H, Hengartner H, Zinkernagel RM. T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal. Cellular Immunology. 168: 184-92. PMID 8640864 DOI: 10.1006/cimm.1996.0065  0.669
1996 Roost HP, Haag A, Burkhart C, Zinkernagel RM, Hengartner H. Mapping of the dominant neutralizing antigenic site of a virus using infected cells. Journal of Immunological Methods. 189: 233-42. PMID 8613674 DOI: 10.1016/0022-1759(95)00252-9  0.606
1996 Battegay M, Bachmann MF, Burhkart C, Viville S, Benoist C, Mathis D, Hengartner H, Zinkernagel RM. Antiviral immune responses of mice lacking MHC class II or its associated invariant chain. Cellular Immunology. 167: 115-21. PMID 8548834 DOI: 10.1006/Cimm.1996.0014  0.648
1995 Zinkernagel RM, Hengartner H. Viral immunopathology. Introduction. Springer Seminars in Immunopathology. 17: 119-20. PMID 8571163 DOI: 10.1007/BF00196160  0.46
1995 van den Broek MF, Kägi D, Zinkernagel RM, Hengartner H. Perforin dependence of natural killer cell-mediated tumor control in vivo. European Journal of Immunology. 25: 3514-6. PMID 8566046 DOI: 10.1002/eji.1830251246  0.632
1995 Bachmann MF, Hengartner H, Zinkernagel RM. T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction? European Journal of Immunology. 25: 3445-51. PMID 8566036 DOI: 10.1002/eji.1830251236  0.652
1995 Oxenius A, Bachmann MF, Ashton-Rickardt PG, Tonegawa S, Zinkernagel RM, Hengartner H. Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system. European Journal of Immunology. 25: 3402-11. PMID 8566030 DOI: 10.1002/Eji.1830251230  0.531
1995 Stallmach T, Ehrenstein T, Isenmann S, Müller C, Hengartner H, Kägi D. The role of perforin-expression by granular metrial gland cells in pregnancy. European Journal of Immunology. 25: 3342-8. PMID 8566021 DOI: 10.1002/eji.1830251221  0.434
1995 Kägi D, Seiler P, Pavlovic J, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses. European Journal of Immunology. 25: 3256-62. PMID 8566009 DOI: 10.1002/eji.1830251209  0.654
1995 Steinhoff U, Müller U, Schertler A, Hengartner H, Aguet M, Zinkernagel RM. Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice. Journal of Virology. 69: 2153-8. PMID 7884863 DOI: 10.1128/Jvi.69.4.2153-2158.1995  0.576
1995 Roost HP, Bachmann MF, Haag A, Kalinke U, Pliska V, Hengartner H, Zinkernagel RM. Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity. Proceedings of the National Academy of Sciences of the United States of America. 92: 1257-61. PMID 7877965 DOI: 10.1073/Pnas.92.5.1257  0.571
1995 Kündig TM, Bachmann MF, DiPaolo C, Simard JJ, Battegay M, Lother H, Gessner A, Kühlcke K, Ohashi PS, Hengartner H. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science (New York, N.Y.). 268: 1343-7. PMID 7761853 DOI: 10.1126/Science.7761853  0.539
1995 Bachmann MF, Oxenius A, Pircher H, Hengartner H, Ashton-Richardt PA, Tonegawa S, Zinkernagel RM. TAP1-independent loading of class I molecules by exogenous viral proteins. European Journal of Immunology. 25: 1739-43. PMID 7615001 DOI: 10.1002/eji.1830250637  0.592
1995 Bachmann MF, Schorle H, Kühn R, Müller W, Hengartner H, Zinkernagel RM, Horak I. Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4. Journal of Virology. 69: 4842-6. PMID 7609051 DOI: 10.1128/Jvi.69.8.4842-4846.1995  0.529
1995 Brändle D, Brduscha-Riem K, Hayday AC, Owen MJ, Hengartner H, Pircher H. T cell development and repertoire of mice expressing a single T cell receptor alpha chain. European Journal of Immunology. 25: 2650-5. PMID 7589140 DOI: 10.1002/Eji.1830250937  0.511
1995 Aichele P, Brduscha-Riem K, Zinkernagel RM, Hengartner H, Pircher H. T cell priming versus T cell tolerance induced by synthetic peptides. The Journal of Experimental Medicine. 182: 261-6. PMID 7540654 DOI: 10.1084/jem.182.1.261  0.591
1995 Freer G, Burkhart C, Rülicke T, Ghelardi E, Rohrer UH, Pircher H, Zinkernagel RM, Hengartner H. Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse. European Journal of Immunology. 25: 1410-6. PMID 7539759 DOI: 10.1002/eji.1830250541  0.684
1995 Schulz M, Schuurman HJ, Joergensen J, Steiner C, Meerloo T, Kägi D, Hengartner H, Zinkernagel RM, Schreier MH, Bürki K. Acute rejection of vascular heart allografts by perforin-deficient mice. European Journal of Immunology. 25: 474-80. PMID 7533086 DOI: 10.1002/Eji.1830250225  0.553
1995 Kägi D, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. Lymphocyte-mediated cytotoxicity in vitro and in vivo: mechanisms and significance. Immunological Reviews. 146: 95-115. PMID 7493763 DOI: 10.1111/J.1600-065X.1995.Tb00686.X  0.517
1994 Aichele P, Kyburz D, Ohashi PS, Odermatt B, Zinkernagel RM, Hengartner H, Pircher H. Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America. 91: 444-8. PMID 8290546 DOI: 10.1073/Pnas.91.2.444  0.621
1994 Moskophidis D, Lechner F, Hengartner H, Zinkernagel RM. MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice. Journal of Immunology (Baltimore, Md. : 1950). 152: 4976-83. PMID 8176216  0.604
1994 Kägi D, Ledermann B, Bürki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature. 369: 31-7. PMID 8164737 DOI: 10.1038/369031A0  0.672
1994 Bachmann MF, Kündig TM, Freer G, Li Y, Kang CY, Bishop DH, Hengartner H, Zinkernagel RM. Induction of protective cytotoxic T cells with viral proteins. European Journal of Immunology. 24: 2228-36. PMID 8088338 DOI: 10.1002/eji.1830240944  0.684
1994 Brändle D, Müller S, Müller C, Hengartner H, Pircher H. Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. European Journal of Immunology. 24: 145-51. PMID 8020549 DOI: 10.1002/eji.1830240122  0.339
1994 Bachmann MF, Bast C, Hengartner H, Zinkernagel RM. Immunogenicity of a viral model vaccine after different inactivation procedures. Medical Microbiology and Immunology. 183: 95-104. PMID 7935164 DOI: 10.1007/Bf00277160  0.581
1994 Bachmann MF, Kündig TM, Odermatt B, Hengartner H, Zinkernagel RM. Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells. Journal of Immunology (Baltimore, Md. : 1950). 153: 3386-97. PMID 7930564  0.497
1994 Bachmann MF, Kündig TM, Hengartner H, Zinkernagel RM. Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen. European Journal of Immunology. 24: 2567-70. PMID 7925584 DOI: 10.1002/eji.1830241046  0.616
1994 Oehen SU, Ohashi PS, Bürki K, Hengartner H, Zinkernagel RM, Aichele P. Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels. Cellular Immunology. 158: 342-52. PMID 7923387 DOI: 10.1006/cimm.1994.1281  0.617
1994 Pircher H, Ohashi PS, Boyd RL, Hengartner H, Brduscha K. Evidence for a selective and multi-step model of T cell differentiation: CD4+CD8low thymocytes selected by a transgenic T cell receptor on major histocompatibility complex class I molecules. European Journal of Immunology. 24: 1982-7. PMID 7916293 DOI: 10.1002/eji.1830240907  0.398
1994 Zinkernagel RM, Hengartner H. T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS. Immunology Today. 15: 262-8. PMID 7915115 DOI: 10.1016/0167-5699(94)90005-1  0.614
1994 Battegay M, Moskophidis D, Rahemtulla A, Hengartner H, Mak TW, Zinkernagel RM. Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice. Journal of Virology. 68: 4700-4. PMID 7911534  0.577
1994 Freer G, Burkhart C, Ciernik I, Bachmann MF, Hengartner H, Zinkernagel RM. Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen. Journal of Virology. 68: 3650-5. PMID 7910641 DOI: 10.1128/Jvi.68.6.3650-3655.1994  0.688
1994 Steinhoff U, Burkhart C, Arnheiter H, Hengartner H, Zinkernagel R. Virus or a hapten-carrier complex can activate autoreactive B cells by providing linked T help. European Journal of Immunology. 24: 773-6. PMID 7907298 DOI: 10.1002/eji.1830240343  0.631
1994 Kägi D, Ledermann B, Bürki K, Hengartner H, Zinkernagel RM. CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. European Journal of Immunology. 24: 3068-72. PMID 7805735 DOI: 10.1002/eji.1830241223  0.655
1994 Bachmann MF, Rohrer UH, Steinhoff U, Bürki K, Skuntz S, Arnheiter H, Hengartner H, Zinkernagel RM. T helper cell unresponsiveness: rapid induction in antigen-transgenic and reversion in non-transgenic mice. European Journal of Immunology. 24: 2966-73. PMID 7805723 DOI: 10.1002/eji.1830241207  0.677
1994 Bachmann MF, Hengartner H, Zinkernagel RM. Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction. Medical Microbiology and Immunology. 183: 315-24. PMID 7596314 DOI: 10.1007/Bf00196682  0.604
1994 Burkhart C, Freer G, Steinhoff U, Li Y, Bishop DH, Zinkernagel RM, Hengartner H. Localization of T helper cell epitopes in the vesicular stomatitis virus: the nucleoprotein is responsible for serotype cross-reactive T help. Viral Immunology. 7: 103-11. PMID 7541205 DOI: 10.1089/vim.1994.7.103  0.662
1994 Kägi D, Vignaux F, Ledermann B, Bürki K, Depraetere V, Nagata S, Hengartner H, Golstein P. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science (New York, N.Y.). 265: 528-30. PMID 7518614 DOI: 10.1126/Science.7518614  0.481
1994 Harlan DM, Hengartner H, Huang ML, Kang YH, Abe R, Moreadith RW, Pircher H, Gray GS, Ohashi PS, Freeman GJ. Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proceedings of the National Academy of Sciences of the United States of America. 91: 3137-41. PMID 7512724 DOI: 10.1073/pnas.91.8.3137  0.528
1994 Bachmann MF, Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. How many specific B cells are needed to protect against a virus? Journal of Immunology (Baltimore, Md. : 1950). 152: 4235-41. PMID 7512589  0.562
1994 Burkhart C, Freer G, Castro R, Adorini L, Wiesmüller KH, Zinkernagel RM, Hengartner H. Characterization of T-helper epitopes of the glycoprotein of vesicular stomatitis virus. Journal of Virology. 68: 1573-80. PMID 7508998 DOI: 10.1128/Jvi.68.3.1573-1580.1994  0.688
1993 Schilham MW, Fung-Leung WP, Rahemtulla A, Kuendig T, Zhang L, Potter J, Miller RG, Hengartner H, Mak TW. Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8. European Journal of Immunology. 23: 1299-304. PMID 8500525 DOI: 10.1002/eji.1830230617  0.501
1993 Ohashi PS, Oehen S, Aichele P, Pircher H, Odermatt B, Herrera P, Higuchi Y, Buerki K, Hengartner H, Zinkernagel RM. Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha. Journal of Immunology (Baltimore, Md. : 1950). 150: 5185-94. PMID 8496610  0.524
1993 Zinkernagel RM, Hengartner H. [Model concepts on the development of so-called autoimmune diseases]. Therapeutische Umschau. Revue Thã©Rapeutique. 50: 66-70. PMID 8456417  0.418
1993 Ohashi PS, Zinkernagel RM, Leuscher I, Hengartner H, Pircher H. Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection. International Immunology. 5: 131-8. PMID 8452813 DOI: 10.1093/intimm/5.2.131  0.57
1993 Kündig TM, Hengartner H, Zinkernagel RM. T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs. Journal of Immunology (Baltimore, Md. : 1950). 150: 2316-21. PMID 8450214  0.619
1993 Zinkernagel RM, Hengartner H. Contra: CD8+ T-cell-mediated suppression without 'suppressor' T cells? International Archives of Allergy and Immunology. 100: 8-11. PMID 8428169 DOI: 10.1159/000236380  0.68
1993 Castelmur I, DiPaolo C, Bachmann MF, Hengartner H, Zinkernagel RM, Kündig TM. Comparison of the sensitivity of in vivo and in vitro assays for detection of antiviral cytotoxic T cell activity. Cellular Immunology. 151: 460-6. PMID 8402949 DOI: 10.1006/cimm.1993.1254  0.552
1993 Bachmann MF, Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. Formalin inactivation of vesicular stomatitis virus impairs T-cell- but not T-help-independent B-cell responses. Journal of Virology. 67: 3917-22. PMID 8389912 DOI: 10.1128/Jvi.67.7.3917-3922.1993  0.689
1993 Kyburz D, Aichele P, Speiser DE, Hengartner H, Zinkernagel RM, Pircher H. T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. European Journal of Immunology. 23: 1956-62. PMID 8344359 DOI: 10.1002/eji.1830230834  0.672
1993 Kyburz D, Speiser DE, Battegay M, Hengartner H, Zinkernagel RM. Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins. European Journal of Immunology. 23: 1540-5. PMID 8325330 DOI: 10.1002/eji.1830230722  0.649
1993 Battegay M, Kyburz D, Hengartner H, Zinkernagel RM. Enhancement of disease by neutralizing antiviral antibodies in the absence of primed antiviral cytotoxic T cells. European Journal of Immunology. 23: 3236-41. PMID 8258339 DOI: 10.1002/eji.1830231229  0.683
1993 Kündig TM, Kalberer CP, Hengartner H, Zinkernagel RM. Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination. Vaccine. 11: 1154-8. PMID 8249436 DOI: 10.1016/0264-410X(93)90079-D  0.568
1993 Bachmann MF, Rohrer UH, Kündig TM, Bürki K, Hengartner H, Zinkernagel RM. The influence of antigen organization on B cell responsiveness. Science (New York, N.Y.). 262: 1448-51. PMID 8248784 DOI: 10.1126/Science.8248784  0.606
1993 Kündig TM, Schorle H, Bachmann MF, Hengartner H, Zinkernagel RM, Horak I. Immune responses in interleukin-2-deficient mice. Science (New York, N.Y.). 262: 1059-61. PMID 8235625 DOI: 10.1126/Science.8235625  0.614
1993 Zinkernagel RM, Moskophidis D, Kündig T, Oehen S, Pircher H, Hengartner H. Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunological Reviews. 133: 199-223. PMID 8225368 DOI: 10.1111/J.1600-065X.1993.Tb01517.X  0.603
1993 Kündig TM, Bachmann MF, Lefrancois L, Puddington L, Hengartner H, Zinkernagel RM. Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells. Journal of Immunology (Baltimore, Md. : 1950). 150: 4450-6. PMID 8097755  0.521
1993 Pircher H, Brduscha K, Steinhoff U, Kasai M, Mizuochi T, Zinkernagel RM, Hengartner H, Kyewski B, Müller KP. Tolerance induction by clonal deletion of CD4+8+ thymocytes in vitro does not require dedicated antigen-presenting cells. European Journal of Immunology. 23: 669-74. PMID 8095457 DOI: 10.1002/eji.1830230315  0.641
1993 Battegay M, Moskophidis D, Waldner H, Bründler MA, Fung-Leung WP, Mak TW, Hengartner H, Zinkernagel RM. Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells. Journal of Immunology (Baltimore, Md. : 1950). 151: 5408-15. PMID 7693811  0.583
1993 Kündig TM, Castelmur I, Bachmann MF, Abraham D, Binder D, Hengartner H, Zinkernagel RM. Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus. Journal of Virology. 67: 3680-3. PMID 7684471 DOI: 10.1128/Jvi.67.6.3680-3683.1993  0.666
1993 Kyburz D, Speiser DE, Aebischer T, Hengartner H, Zinkernagel RM. Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 150: 5051-8. PMID 7684417  0.629
1992 Speiser DE, Kyburz D, Stübi U, Hengartner H, Zinkernagel RM. Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection. Journal of Immunology (Baltimore, Md. : 1950). 149: 972-80. PMID 1634779  0.608
1992 Zinkernagel RM, Hengartner H. T cells causing immunological disease: immunopathology or autoimmunity? Research in Immunology. 143: 310-3. PMID 1631413  0.532
1992 Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM. Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation. European Journal of Immunology. 22: 1803-12. PMID 1623925 DOI: 10.1002/Eji.1830220720  0.67
1992 Moskophidis D, Pircher H, Ciernik I, Odermatt B, Hengartner H, Zinkernagel RM. Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo. Journal of Virology. 66: 3661-8. PMID 1583725 DOI: 10.1128/Jvi.66.6.3661-3668.1992  0.7
1992 Speiser DE, Pircher H, Ohashi PS, Kyburz D, Hengartner H, Zinkernagel RM. Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. The Journal of Experimental Medicine. 175: 1277-83. PMID 1533241 DOI: 10.1084/Jem.175.5.1277  0.639
1992 Tomonari K, Hederer R, Hengartner H. Positive selection of Tcrb-V10b+ T cells. Immunogenetics. 35: 9-15. PMID 1530842 DOI: 10.1007/Bf00216621  0.477
1992 Zinkernagel RM, Pircher H, Ohashi PS, Hengartner H. T cells causing immunological disease. Springer Seminars in Immunopathology. 14: 105-13. PMID 1475738 DOI: 10.1007/BF00195288  0.621
1992 Oehen S, Ohashi PS, Aichele P, Bürki K, Hengartner H, Zinkernagel RM. Vaccination or tolerance to prevent diabetes. European Journal of Immunology. 22: 3149-53. PMID 1446706 DOI: 10.1002/eji.1830221218  0.603
1992 Oehen S, Waldner H, Kündig TM, Hengartner H, Zinkernagel RM. Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen. The Journal of Experimental Medicine. 176: 1273-81. PMID 1402673 DOI: 10.1084/Jem.176.5.1273  0.644
1992 Pircher H, Müller KP, Kyewski BA, Hengartner H. Thymocytes can tolerize thymocytes by clonal deletion in vitro. International Immunology. 4: 1065-9. PMID 1390437 DOI: 10.1093/Intimm/4.9.1065  0.447
1992 Zinkernagel RM, Hengartner H. Virally induced immunosuppression. Current Opinion in Immunology. 4: 408-12. PMID 1388842 DOI: 10.1016/S0952-7915(06)80031-2  0.685
1992 Schneider R, Pircher H, Speiser DE, Zinkernagel R, Hengartner H. Kinetics of clonal deletion varies with tolerizing antigen. Thymus. 20: 5-15. PMID 1387745  0.356
1992 Battegay M, Oehen S, Schulz M, Hengartner H, Zinkernagel RM. Vaccination with a synthetic peptide modulates lymphocytic choriomeningitis virus-mediated immunopathology. Journal of Virology. 66: 1199-201. PMID 1370548 DOI: 10.1128/Jvi.66.2.1199-1201.1992  0.618
1992 Brändle D, Müller C, Rülicke T, Hengartner H, Pircher H. Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression. Proceedings of the National Academy of Sciences of the United States of America. 89: 9529-33. PMID 1329099 DOI: 10.1073/Pnas.89.20.9529  0.359
1992 Kündig TM, Althage A, Hengartner H, Zinkernagel RM. Skin test to assess virus-specific cytotoxic T-cell activity. Proceedings of the National Academy of Sciences of the United States of America. 89: 7757-61. PMID 1323850 DOI: 10.1073/Pnas.89.16.7757  0.626
1992 Pircher H, Rebaï N, Groettrup M, Grégoire C, Speiser DE, Happ MP, Palmer E, Zinkernagel RM, Hengartner H, Malissen B. Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody. European Journal of Immunology. 22: 399-404. PMID 1311260 DOI: 10.1002/eji.1830220217  0.541
1991 Schulz M, Zinkernagel RM, Hengartner H. Peptide-induced antiviral protection by cytotoxic T cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 991-3. PMID 1992491 DOI: 10.1073/PNAS.88.3.991  0.631
1991 Battegay M, Cooper S, Althage A, Bänziger J, Hengartner H, Zinkernagel RM. Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates. Journal of Virological Methods. 33: 191-8. PMID 1939506 DOI: 10.1016/0166-0934(91)90018-U  0.578
1991 Zinkernagel RM, Pircher HP, Ohashi P, Oehen S, Odermatt B, Mak T, Arnheiter H, Bürki K, Hengartner H. T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease. Immunological Reviews. 122: 133-71. PMID 1937540 DOI: 10.1111/J.1600-065X.1991.Tb00601.X  0.691
1991 Podack ER, Hengartner H, Lichtenheld MG. A central role of perforin in cytolysis? Annual Review of Immunology. 9: 129-57. PMID 1910674 DOI: 10.1146/Annurev.Iy.09.040191.001021  0.345
1991 Odermatt B, Eppler M, Leist TP, Hengartner H, Zinkernagel RM. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proceedings of the National Academy of Sciences of the United States of America. 88: 8252-6. PMID 1910175 DOI: 10.1073/PNAS.88.18.8252  0.692
1991 Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, Odermatt B, Malissen B, Zinkernagel RM, Hengartner H. Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell. 65: 305-17. PMID 1901764 DOI: 10.1016/0092-8674(91)90164-T  0.679
1991 Oehen S, Hengartner H, Zinkernagel RM. Vaccination for disease. Science (New York, N.Y.). 251: 195-8. PMID 1824801 DOI: 10.1126/SCIENCE.1824801  0.525
1991 Aebischer T, Moskophidis D, Rohrer UH, Zinkernagel RM, Hengartner H. In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 88: 11047-51. PMID 1722316 DOI: 10.1073/Pnas.88.24.11047  0.666
1991 Zinkernagel RM, Hengartner H. HIV. Games that viruses play. Nature. 354: 433-4. PMID 1721106 DOI: 10.1038/354433a0  0.424
1991 Brändle D, Bürki K, Wallace VA, Rohrer UH, Mak TW, Malissen B, Hengartner H, Pircher H. Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition. European Journal of Immunology. 21: 2195-202. PMID 1716213 DOI: 10.1002/eji.1830210930  0.386
1991 Pircher H, Rohrer UH, Moskophidis D, Zinkernagel RM, Hengartner H. Lower receptor avidity required for thymic clonal deletion than for effector T-cell function. Nature. 351: 482-5. PMID 1710780 DOI: 10.1038/351482A0  0.666
1991 Schulz M, Aichele P, Schneider R, Hansen TH, Zinkernagel RM, Hengartner H. Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide. European Journal of Immunology. 21: 1181-5. PMID 1709866 DOI: 10.1002/eji.1830210513  0.618
1991 Oehen S, Hengartner H, Zinkernagel R. Recombinant vaccines. Lancet. 337: 1542. PMID 1675384 DOI: 10.1016/0140-6736(91)93228-2  0.347
1990 Ohashi PS, Wallace VA, Broughton H, Ohashi CT, Ferrick DA, Jost V, Mak TW, Hengartner H, Pircher H. Specific deletion of the J-C delta locus in murine alpha/beta T cell clones and studies using transgenic mice. European Journal of Immunology. 20: 517-22. PMID 2318248 DOI: 10.1002/eji.1830200309  0.399
1990 Speiser DE, Zürcher T, Ramseier H, Hengartner H, Staeheli P, Haller O, Zinkernagel RM. Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 2021-5. PMID 2308961 DOI: 10.1073/PNAS.87.5.2021  0.623
1990 Kohler M, Rüttner B, Cooper S, Hengartner H, Zinkernagel RM. Enhanced tumor susceptibility of immunocompetent mice infected with lymphocytic choriomeningitis virus. Cancer Immunology, Immunotherapy : Cii. 32: 117-24. PMID 2289203 DOI: 10.1007/BF01754208  0.568
1990 Rüedi E, Hengartner H, Zinkernagel RM. Immunosuppression in mice by lymphocytic choriomeningitis virus infection: time dependence during primary and absence of effects on secondary antibody responses. Cellular Immunology. 130: 501-12. PMID 2170031 DOI: 10.1016/0008-8749(90)90290-8  0.571
1990 Zinkernagel RM, Cooper S, Chambers J, Lazzarini RA, Hengartner H, Arnheiter H. Virus-induced autoantibody response to a transgenic viral antigen. Nature. 345: 68-71. PMID 2158632 DOI: 10.1038/345068A0  0.677
1990 Groscurth P, Diener S, Stahel R, Jost L, Kägi D, Hengartner H. Morphologic analysis of human lymphokine-activated killer (LAK) cells. International Journal of Cancer. Journal International Du Cancer. 45: 694-704. PMID 2157676 DOI: 10.1002/Ijc.2910450422  0.402
1990 Aebischer T, Oehen S, Hengartner H. Preferential usage of V alpha 4 and V beta 10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein-specific H-2Db-restricted cytotoxic T cells. European Journal of Immunology. 20: 523-31. PMID 2138558 DOI: 10.1002/eji.1830200310  0.416
1990 Ohashi PS, Pircher H, Bürki K, Zinkernagel RM, Hengartner H. Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities. Nature. 346: 861-3. PMID 1975427 DOI: 10.1038/346861a0  0.534
1990 Pircher H, Ohashi P, Miescher G, Lang R, Zikopoulos A, Bürki K, Mak TW, MacDonald HR, Hengartner H. T cell receptor (TcR) beta chain transgenic mice: studies on allelic exclusion and on the TcR+ gamma/delta population. European Journal of Immunology. 20: 417-24. PMID 1968840 DOI: 10.1002/Eji.1830200227  0.414
1990 Pircher H, Moskophidis D, Rohrer U, Bürki K, Hengartner H, Zinkernagel RM. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature. 346: 629-33. PMID 1696684 DOI: 10.1038/346629A0  0.66
1990 Aichele P, Hengartner H, Zinkernagel RM, Schulz M. Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. The Journal of Experimental Medicine. 171: 1815-20. PMID 1692084 DOI: 10.1084/JEM.171.5.1815  0.662
1989 Ohashi PS, Pircher H, Mak TW, Bürki K, Zinkernagel RM, Hengartner H. Ontogeny and selection of the T cell repertoire in transgenic mice. Seminars in Immunology. 1: 95-104. PMID 15630811  0.365
1989 Gobet R, Cerny A, Rüedi E, Hengartner H, Zinkernagel RM. The role of antibodies in natural and acquired resistance of mice to vesicular stomatitis virus. Experimental Cell Biology. 56: 175-80. PMID 2849570 DOI: 10.1159/000163477  0.612
1989 Lowrey DM, Aebischer T, Olsen K, Lichtenheld M, Rupp F, Hengartner H, Podack ER. Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9. Proceedings of the National Academy of Sciences of the United States of America. 86: 247-51. PMID 2783486 DOI: 10.1073/Pnas.86.1.247  0.644
1989 Leist T, Althage A, Haenseler E, Hengartner H, Zinkernagel RM. Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated. The Journal of Experimental Medicine. 170: 269-77. PMID 2746160 DOI: 10.1084/JEM.170.1.269  0.65
1989 Zinkernagel RM, Pircher HP, Schulz M, Leist T, Oehen S, Hengartner H. Reactivity and tolerance of virus-specific T cells. Cold Spring Harbor Symposia On Quantitative Biology. 54: 843-51. PMID 2701218 DOI: 10.1101/SQB.1989.054.01.098  0.656
1989 Müller C, Kägi D, Aebischer T, Odermatt B, Held W, Podack ER, Zinkernagel RM, Hengartner H. Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus. European Journal of Immunology. 19: 1253-9. PMID 2668013 DOI: 10.1002/Eji.1830190716  0.61
1989 Pircher H, Bürki K, Lang R, Hengartner H, Zinkernagel RM. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature. 342: 559-61. PMID 2573841 DOI: 10.1038/342559a0  0.664
1989 Schneider R, Lees R, Pedrazzini T, Odermatt B, Speiser DE, Zinkernagel RM, Hengartner H, MacDonald HR. Fate of potentially self-reactive T cells in neonatal mice: analysis of V beta 6+ T cells in Mlsa mice. Thymus. 13: 35-43. PMID 2533756  0.309
1989 Speiser DE, Kolb E, Schneider R, Pircher H, Hengartner H, MacDonald HR, Zinkernagel RM. Tolerance to Mlsa by clonal deletion of V beta 6+ T cells in bone marrow and thymus chimeras. Thymus. 13: 27-33. PMID 2533754  0.345
1989 Speiser DE, Schneider R, Hengartner H, MacDonald HR, Zinkernagel RM. Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa. The Journal of Experimental Medicine. 170: 595-600. PMID 2526850 DOI: 10.1084/Jem.170.2.595  0.59
1989 Pircher H, Mak TW, Lang R, Ballhausen W, Rüedi E, Hengartner H, Zinkernagel RM, Bürki K. T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. The Embo Journal. 8: 719-27. PMID 2524380  0.414
1989 MacDonald HR, Glasebrook AL, Schneider R, Lees RK, Pircher H, Pedrazzini T, Kanagawa O, Nicolas J, Howe RC, Zinkernagel RM, Hengartner H. T-cell reactivity and tolerance to Mlsa-encoded antigens. Immunological Reviews. 107: 89-108. PMID 2522087 DOI: 10.1111/J.1600-065X.1989.Tb00004.X  0.64
1989 MacDonald HR, Speiser D, Lees R, Schneider R, Zinkernagel RM, Hengartner H. Positive and negative selection of the T-cell antigen receptor repertoire in nontransgenic mice. Cold Spring Harbor Symposia On Quantitative Biology. 54: 129-33. PMID 2517917 DOI: 10.1101/Sqb.1989.054.01.016  0.607
1989 Speiser DE, Lees RK, Hengartner H, Zinkernagel RM, MacDonald HR. Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus. The Journal of Experimental Medicine. 170: 2165-70. PMID 2511269 DOI: 10.1084/Jem.170.6.2165  0.574
1989 Schulz M, Aichele P, Vollenweider M, Bobe FW, Cardinaux F, Hengartner H, Zinkernagel RM. Major histocompatibility complex--dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease. European Journal of Immunology. 19: 1657-67. PMID 2477254 DOI: 10.1002/eji.1830190921  0.659
1989 Schneider R, Lees RK, Pedrazzini T, Zinkernagel RM, Hengartner H, MacDonald HR. Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity. The Journal of Experimental Medicine. 169: 2149-58. PMID 2471774 DOI: 10.1084/Jem.169.6.2149  0.454
1989 Rüedi E, Sykes M, Ildstad ST, Chester CH, Althage A, Hengartner H, Sachs DH, Zinkernagel RM. Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras. Cellular Immunology. 121: 185-95. PMID 2470518 DOI: 10.1016/0008-8749(89)90016-6  0.673
1989 Hany M, Oehen S, Schulz M, Hengartner H, Mackett M, Bishop DH, Overton H, Zinkernagel RM. Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein. European Journal of Immunology. 19: 417-24. PMID 2468501 DOI: 10.1002/eji.1830190302  0.619
1989 Pircher H, Mak TW, Lang R, Ballhausen W, Rüedi E, Hengartner H, Zinkernagel RM, Bürki K. T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. The Embo Journal. 8: 719-727. DOI: 10.1002/j.1460-2075.1989.tb03431.x  0.639
1988 Schott H, Leitner B, Schwendener RA, Hengartner H. Chromatography of functionalized liposomes and their components Journal of Chromatography A. 441: 115-124. PMID 3403675 DOI: 10.1016/S0021-9673(01)84659-8  0.316
1988 Podack ER, Lowrey DM, Lichtenheld M, Olsen KJ, Aebischer T, Binder D, Rupp F, Hengartner H. Structure, function and expression of murine and human perforin 1 (P1). Immunological Reviews. 103: 203-11. PMID 3292394 DOI: 10.1111/J.1600-065X.1988.Tb00756.X  0.549
1988 Baenziger J, Hengartner H, Zinkernagel RM, Groscurth P. Distinct patterns of virus-specific T cell-mediated cytolysis of transformed versus primary target cells. Scandinavian Journal of Immunology. 28: 411-23. PMID 3264082 DOI: 10.1111/j.1365-3083.1988.tb01470.x  0.566
1988 MacDonald HR, Lees RK, Schneider R, Zinkernagel RM, Hengartner H. Positive selection of CD4+ thymocytes controlled by MHC class II gene products. Nature. 336: 471-3. PMID 3264054 DOI: 10.1038/336471a0  0.605
1988 Hengartner H, Odermatt B, Schneider R, Schreyer M, Wälle G, MacDonald HR, Zinkernagel RM. Deletion of self-reactive T cells before entry into the thymus medulla. Nature. 336: 388-90. PMID 3264053 DOI: 10.1038/336388a0  0.631
1988 Cerny A, Sutter S, Bazin H, Hengartner H, Zinkernagel RM. Clearance of lymphocytic choriomeningitis virus in antibody- and B-cell-deprived mice. Journal of Virology. 62: 1803-7. PMID 3258641 DOI: 10.1128/JVI.62.5.1803-1807.1988  0.638
1988 Cerny A, Hügin AW, Bazin H, Sutter S, Hengartner H, Zinkernagel RM. Anti-Listeria monocytogenes immunity in mu-suppressed mice: a comparison of treatment with conventional hyperimmune rabbit anti-mouse IgM and affinity-purified, monoclonal rat anti-mouse IgM. Medical Microbiology and Immunology. 177: 123-31. PMID 3134601 DOI: 10.1007/BF00232892  0.581
1988 MacDonald HR, Schneider R, Lees RK, Howe RC, Acha-Orbea H, Festenstein H, Zinkernagel RM, Hengartner H. T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature. 332: 40-5. PMID 3126397 DOI: 10.1038/332040A0  0.589
1988 Zinkernagel RM, Rüedi E, Althage A, Hengartner H, Reimann G. Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells. The Journal of Experimental Medicine. 168: 1187-92. PMID 2971754 DOI: 10.1084/JEM.168.3.1187  0.692
1988 MacDonald HR, Hengartner H, Pedrazzini T. Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment. Nature. 335: 174-6. PMID 2970592 DOI: 10.1038/335174A0  0.459
1988 Schulz M, Lienhard G, Rupp F, Zinkernagel RM, Hengartner H. Expression of T cell receptor gamma-chain in murine cytotoxic T cells: analysis of a highly transcribed nonrearranged gene cluster. Experimental Cell Biology. 56: 181-9. PMID 2849571 DOI: 10.1159/000163478  0.71
1988 Payne J, Huber BT, Cannon NA, Schneider R, Schilham MW, Acha-Orbea H, MacDonald HR, Hengartner H. Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7695-8. PMID 2459713 DOI: 10.1073/Pnas.85.20.7695  0.446
1988 Roost H, Charan S, Gobet R, Rüedi E, Hengartner H, and AAA, Zinkernagel RM. An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus. European Journal of Immunology. 18: 511-518. PMID 2452742 DOI: 10.1002/Eji.1830180404  0.675
1988 Schott H, Leitner B, Hengartner H, Schwendener RA. Chromatographic purification steps involved in the synthesis of prodrug-liposome-antibody-complexes Chromatographia. 25: 210-214. DOI: 10.1007/BF02316446  0.308
1987 Fruth U, Prester M, Golecki JR, Hengartner H, Simon HG, Kramer MD, Simon MM. The T cell-specific serine proteinase TSP-1 is associated with cytoplasmic granules of cytolytic T lymphocytes European Journal of Immunology. 17: 613-621. PMID 3556195 DOI: 10.1002/eji.1830170506  0.394
1987 Lowrey DM, Rupp F, Aebischer T, Grey P, Hengartner H, Podack ER. Primary sequence homology between the effector molecules that mediate complement and T-lymphocyte cytotoxicity. Annales De L'Institut Pasteur. Immunology. 138: 296-300. PMID 3496905 DOI: 10.1016/S0769-2625(87)80082-X  0.647
1987 Schilham MW, Lang R, Acha-Orbea H, Benner R, Joho R, Hengartner H. Fine specificity and T-cell receptor beta-chain gene rearrangements of five H-2Db-specific cytotoxic T-cell clones. Immunogenetics. 25: 171-178. PMID 3493974 DOI: 10.1007/Bf00344031  0.464
1987 Pircher H, Baenziger J, Schilham M, Sado T, Kamisaku H, Hengartner H, Zinkernagel RM. Characterization of virus-specific cytotoxic T cell clones from allogeneic bone marrow chimeras European Journal of Immunology. 17: 159-166. PMID 3493906 DOI: 10.1002/eji.1830170202  0.57
1987 Iwamoto A, Ohashi PS, Pircher H, Walker CL, Michalopoulos EE, Rupp F, Hengartner H, Mak TW. T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones. The Journal of Experimental Medicine. 165: 591-600. PMID 3493320 DOI: 10.1084/jem.165.3.591  0.661
1987 Rupp F, Brecher J, Giedlin MA, Mosmann T, Zinkernagel RM, Hengartner H, Joho RH. T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes. Proceedings of the National Academy of Sciences of the United States of America. 84: 219-22. PMID 3491990 DOI: 10.1073/Pnas.84.1.219  0.731
1987 Pircher H, Michalopoulos EE, Iwamoto A, Ohashi PS, Baenziger J, Hengartner H, Zinkernagel RM, Mak TW. Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V(α) family European Journal of Immunology. 17: 1843-1846. PMID 2961577 DOI: 10.1002/Eji.1830171226  0.509
1987 Charan S, Hengartner H, Zinkernagel RM. Antibodies against the two serotypes of vesicular stomatitis virus measured by enzyme-linked immunosorbent assay: immunodominance of serotype-specific determinants and induction of asymmetrically cross-reactive antibodies. Journal of Virology. 61: 2509-14. PMID 2439706 DOI: 10.1128/JVI.61.8.2509-2514.1987  0.581
1986 Zinkernagel RM, Leist T, Hengartner H, Althage A. Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D. The Journal of Experimental Medicine. 162: 2125-41. PMID 3877779 DOI: 10.1084/JEM.162.6.2125  0.576
1986 Zinkernagel RM, Leist T, Hengartner H, Pestalozzi B, Stitz L. Studies on immunity to lymphocytic choriomeningitis virus. Medical Microbiology and Immunology. 175: 209-11. PMID 3523184 DOI: 10.1007/BF02122453  0.581
1986 Cerny A, Heusser C, Sutter S, Huegin AW, Bazin H, Hengartner H, Zinkernagel RM. Generation of agammaglobulinaemic mice by prenatal and postnatal exposure to polyclonal or monoclonal anti-IgM antibodies. Scandinavian Journal of Immunology. 24: 437-45. PMID 3489985 DOI: 10.1111/j.1365-3083.1986.tb02132.x  0.583
1986 Zinkernagel RM, Haenseler E, Leist T, Cerny A, Hengartner H, Althage A. T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay? The Journal of Experimental Medicine. 164: 1075-92. PMID 3489805 DOI: 10.1084/JEM.164.4.1075  0.652
1986 Baenziger J, Hengartner H, Zinkernagel RM. Cloned cytotoxic T cells specific for lymphocytic choriomeningitis virus induce acute disease and primary footpad swelling in infected mice Medical Microbiology and Immunology. 175: 201-203. PMID 3487709 DOI: 10.1007/BF02122451  0.685
1986 Iwamoto A, Rupp F, Ohashi PS, Walker CL, Pircher H, Joho R, Hengartner H, Mak TW. T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes. The Journal of Experimental Medicine. 163: 1203-12. PMID 3486244 DOI: 10.1084/jem.163.5.1203  0.64
1986 Baenziger J, Hengartner H, Zinkernagel RM, Cole GA. Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus European Journal of Immunology. 16: 387-393. PMID 3084281 DOI: 10.1002/EJI.1830160413  0.656
1986 Rosenthal KL, Zinkernagel RM, Hengartner H, Groscurth P, Dennert G, Takayesu D, Prevec L. Persistence of vesicular stomatitis virus in cloned interleukin-2-dependent natural killer cell lines Journal of Virology. 60: 539-547. PMID 3021987 DOI: 10.1128/JVI.60.2.539-547.1986  0.623
1986 Rupp F, Frech G, Hengartner H, Zinkernagel RM, Joho R. No functional gamma-chain transcripts detected in an alloreactive cytotoxic T-cell clone. Nature. 321: 876-8. PMID 3014341 DOI: 10.1038/321876a0  0.734
1986 Gupta SC, Hengartner H, Zinkernagel RM. Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model. Proceedings of the National Academy of Sciences of the United States of America. 83: 2604-8. PMID 3010314 DOI: 10.1073/PNAS.83.8.2604  0.637
1986 Charan S, Huegin AW, Cerny A, Hengartner H, Zinkernagel RM. Effects of cyclosporin A on humoral immune response and resistance against vesicular stomatitis virus in mice. Journal of Virology. 57: 1139-44. PMID 3005615 DOI: 10.1128/JVI.57.3.1139-1144.1986  0.639
1986 Pircher H, Groscurth P, Baumhütter S, Aguet M, Zinkernagel RM, Hengartner H. A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells. European Journal of Immunology. 16: 172-81. PMID 2420606 DOI: 10.1002/Eji.1830160212  0.617
1985 Zinkernagel RM, Pfau CJ, Hengartner H, Althage A. Susceptibility to murine lymphocytic choriomeningitis maps to class I MHC genes--a model for MHC/disease associations. Nature. 316: 814-7. PMID 4033780 DOI: 10.1038/316814A0  0.632
1985 Zinkernagel RM, Hengartner H, Stitz L. On the role of viruses in the evolution of immune responses. British Medical Bulletin. 41: 92-7. PMID 3882192 DOI: 10.1093/OXFORDJOURNALS.BMB.A072033  0.58
1985 Podack ER, Konigsberg PJ, Acha-Orbea H, Pircher H, Hengartner H. Cytolytic T-cell granules: biochemical properties and functional specificity. Advances in Experimental Medicine and Biology. 184: 99-119. PMID 3875979 DOI: 10.1007/978-1-4684-8326-0_8  0.353
1985 Stitz L, Huang RT, Hengartner H, Rott R, Zinkernagel RM. Cytotoxic T cell lysis of target cells fused with liposomes containing influenza virus haemagglutinin and neuraminidase. The Journal of General Virology. 1333-9. PMID 3874262 DOI: 10.1099/0022-1317-66-6-1333  0.607
1985 Huegin AW, Cerny A, Hengartner H, Zinkernagel RM. Suppression by cyclosporin A of murine T-cell-mediated immunity against viruses in vivo and in vitro. Cellular Immunology. 90: 464-73. PMID 2981641 DOI: 10.1016/0008-8749(85)90211-4  0.673
1985 Rupp F, Acha-Orbea H, Hengartner H, Zinkernagel R, Joho R. Identical V beta T-cell receptor genes used in alloreactive cytotoxic and antigen plus I-A specific helper T cells. Nature. 315: 425-7. PMID 2582268 DOI: 10.1038/315425a0  0.705
1985 Pircher H, Zinkernagel RM, Hengartner H. Inhibition of hapten-specific cytotoxic T cell recognition by monoclonal anti-hapten antibodies. European Journal of Immunology. 15: 228-35. PMID 2579821 DOI: 10.1002/EJI.1830150305  0.566
1985 Acha-Orbea H, Zinkernagel RM, Hengartner H. Cytotoxic T cell clone-specific monoclonal antibodies used to select clonotypic antigen-specific cytotoxic T cells. European Journal of Immunology. 15: 31-6. PMID 2578398 DOI: 10.1002/EJI.1830150107  0.594
1984 Pircher H, Hämmerling G, Hengartner H. Restriction fine specificity of long-term, hapten-specific cytotoxic T cell clones: analysis with H-2Kbm-mutant mice and H-2Kb-specific monoclonal antibodies. European Journal of Immunology. 14: 144-152. PMID 6199212 DOI: 10.1002/Eji.1830140208  0.406
1982 Piontek GE, Grönberg A, Ährlund-Richter L, Kiessling R, Hengartner H. NK-patterned binding expressed by non-NK mouse leukocytes. International Journal of Cancer. 30: 225-229. PMID 7129676 DOI: 10.1002/Ijc.2910300216  0.347
1982 Hengartner H, Acha-Orbea H, Lang R, Stitz L, Rosenthal KL, Groscurth P, Keller R. Permanently Growing Murine Cell Clones With Nk Like Activities Nk Cells and Other Natural Effector Cells. 893-901. DOI: 10.1016/B978-0-12-341360-4.50134-7  0.467
1980 Nabholz M, Conzelmann A, Acuto O, North M, Haas W, Pohlit H, Boehmer HV, Hengartner H, Mach J, Engers H, Johnson JP. Established Murine Cytolytic T-Cell Lines as Tools for a Somatic Cell Genetic Analysis of T-Cell Functions Immunological Reviews. 51: 125-156. PMID 6159300 DOI: 10.1111/J.1600-065X.1980.Tb00319.X  0.443
1980 Hengartner H, Fathman CG. Clones of alloreactive T cells. I. A. unique homozygous MLR-stimulating determinant present on B6 stimulators. Immunogenetics. 10: 175-84. PMID 6158477 DOI: 10.1007/BF01561566  0.308
1980 Leibo SP, Boehmer Hv, Haas W, Hengartner H. Cryopreservation of cytotoxic T-cell clones and their targets Cryobiology. 17: 597. DOI: 10.1016/0011-2240(80)90087-5  0.434
1978 Fathman CG, Hengartner H. Clones of alloreactive T cells. Nature. 272: 617-8. PMID 306067 DOI: 10.1038/272617A0  0.359
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