Laura M. Holsen - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
obesity, food motivation, depression, fMRI

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Duda JM, Moser AD, Ironside M, Null KE, Holsen LM, Zuo CS, Du F, Esfand SM, Chen X, Perlo S, Richards CE, Lobien R, Alexander M, Misra M, Goldstein JM, et al. Effects of GABA, Sex, and Stress on Reward Learning in Current and Remitted Major Depression. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 38417785 DOI: 10.1016/j.bpsc.2024.02.009  0.417
2024 Zhukovsky P, Ironside M, Duda JM, Moser AD, Null KE, Dhaynaut M, Normandin M, Guehl NJ, El Fakhri G, Alexander M, Holsen LM, Misra M, Narendran R, Hoye J, Morris E, et al. Acute stress increases striatal connectivity with cortical regions enriched for μ- and κ-opioid receptors. Biological Psychiatry. PMID 38395372 DOI: 10.1016/j.biopsych.2024.02.005  0.439
2023 Eddy KT, Plessow F, Breithaupt L, Becker KR, Slattery M, Mancuso CJ, Izquierdo AM, Van De Water AL, Kahn DL, Dreier MJ, Ebrahimi S, Deckersbach T, Thomas JJ, Holsen LM, Misra M, et al. Neural activation of regions involved in food reward and cognitive control in young females with anorexia nervosa and atypical anorexia nervosa versus healthy controls. Translational Psychiatry. 13: 220. PMID 37353543 DOI: 10.1038/s41398-023-02494-3  0.428
2023 Cohen JE, Holsen LM, Ironside M, Moser AD, Duda JM, Null KE, Perlo S, Richards CE, Nascimento NF, Du F, Zuo C, Misra M, Pizzagalli DA, Goldstein JM. Neural response to stress differs by sex in young adulthood. Psychiatry Research. Neuroimaging. 332: 111646. PMID 37146439 DOI: 10.1016/j.pscychresns.2023.111646  0.51
2022 Piccolo M, Belleau EL, Holsen LM, Trivedi MH, Parsey RV, McGrath PJ, Weissman MM, Pizzagalli DA, Javaras KN. Alterations in resting-state functional activity and connectivity for major depressive disorder appetite and weight disturbance phenotypes. Psychological Medicine. 1-11. PMID 35670301 DOI: 10.1017/S0033291722001398  0.715
2021 Low AYT, Goldstein N, Gaunt JR, Huang KP, Zainolabidin N, Yip AKK, Carty JRE, Choi JY, Miller AM, Ho HST, Lenherr C, Baltar N, Azim E, Sessions OM, Ch'ng TH, ... ... Holsen LM, et al. Reverse-translational identification of a cerebellar satiation network. Nature. PMID 34789878 DOI: 10.1038/s41586-021-04143-5  0.413
2021 Chang RS, Cerit H, Hye T, Durham EL, Aizley H, Boukezzi S, Haimovici F, Goldstein JM, Dillon DG, Pizzagalli DA, Holsen LM. Stress-induced alterations in HPA-axis reactivity and mesolimbic reward activation in individuals with emotional eating. Appetite. 105707. PMID 34562531 DOI: 10.1016/j.appet.2021.105707  0.483
2021 Ironside M, Moser AD, Holsen LM, Zuo CS, Du F, Perlo S, Richards CE, Duda JM, Chen X, Nickerson LD, Null KE, Nascimento N, Crowley DJ, Misra M, Goldstein JM, et al. Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: a multimodal imaging investigation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34363015 DOI: 10.1038/s41386-021-01127-x  0.503
2021 Kerem L, Van De Water AL, Kuhnle MC, Harshman S, Hauser K, Eddy KT, Becker KR, Misra M, Micali N, Thomas JJ, Holsen L, Lawson EA. Neurobiology of Avoidant/Restrictive Food Intake Disorder in Youth with Overweight/Obesity Versus Healthy Weight. Journal of Clinical Child and Adolescent Psychology : the Official Journal For the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. 1-14. PMID 33769133 DOI: 10.1080/15374416.2021.1894944  0.465
2020 Kerem L, Holsen L, Fazeli P, Bredella MA, Mancuso C, Resulaj M, Holmes TM, Klibanski A, Lawson EA. Modulation of neural fMRI responses to visual food cues by overeating and fasting interventions: A preliminary study. Physiological Reports. 8: e14639. PMID 33369272 DOI: 10.14814/phy2.14639  0.418
2020 Duda JM, Moser AD, Zuo CS, Du F, Chen X, Perlo S, Richards CE, Nascimento N, Ironside M, Crowley DJ, Holsen LM, Misra M, Hudson JI, Goldstein JM, Pizzagalli DA. Repeatability and reliability of GABA measurements with magnetic resonance spectroscopy in healthy young adults. Magnetic Resonance in Medicine. PMID 33216412 DOI: 10.1002/mrm.28587  0.401
2020 Breithaupt L, Chunga-Iturry N, Lyall AE, Cetin-Karayumak S, Becker KR, Thomas JJ, Slattery M, Makris N, Plessow F, Pasternak O, Holsen LM, Kubicki M, Misra M, Lawson EA, Eddy KT. Developmental stage-dependent relationships between ghrelin levels and hippocampal white matter connections in low-weight anorexia nervosa and atypical anorexia nervosa. Psychoneuroendocrinology. 119: 104722. PMID 32512249 DOI: 10.1016/J.Psyneuen.2020.104722  0.446
2020 Garcia RG, Mareckova K, Holsen LM, Cohen J, Whitfield-Gabrieli S, Napadow V, Barbieri R, Goldstein JM. Impact of sex and depressed mood on the central regulation of cardiac autonomic function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32152473 DOI: 10.1038/S41386-020-0651-X  0.387
2020 Getachew ED, Plessow F, Van De Water A, Pulumo RL, Hauser K, Asanza E, Kerem L, Harshman SG, Holsen L, Lawson EA. MON-LB103 Hyperactivation of Reward and Cognitive Control Brain Regions in Response to Food Images in Women Compared to Men With Obesity Journal of the Endocrine Society. 4. DOI: 10.1210/jendso/bvaa046.2308  0.517
2019 Kerem L, Hadjikhani N, Holsen L, Lawson EA, Plessow F. Oxytocin reduces the functional connectivity between brain regions involved in eating behavior in men with overweight and obesity. International Journal of Obesity (2005). PMID 31740723 DOI: 10.1038/s41366-019-0489-7  0.533
2019 Cerit H, Davidson P, Hye T, Moondra P, Haimovici F, Sogg S, Shikora S, Goldstein JM, Evins AE, Whitfield-Gabrieli S, Stoeckel LE, Holsen LM. Resting-State Brain Connectivity Predicts Weight Loss and Cognitive Control of Eating Behavior After Vertical Sleeve Gastrectomy. Obesity (Silver Spring, Md.). 27: 1846-1855. PMID 31689011 DOI: 10.1002/Oby.22607  0.353
2019 Kerem L, Plessow F, Holsen L, Hadjikhani N, Lawson E. OR20-2 Oxytocin Significantly Attenuates the Functional Connectivity between Food Motivation Brain Areas in Overweight and Obese Men Exposed to High Caloric Food Images Journal of the Endocrine Society. 3. DOI: 10.1210/JS.2019-OR20-2  0.496
2019 Boukezzi S, Dillon DG, Cerit H, Durham L, Ryder B, Goldstein JM, Pizzagalli DA, Holsen LM. F18. Sex Differences in Stress-Induced Reward Processing in Major Depressive Disorder (MDD) Biological Psychiatry. 85: S219-S220. DOI: 10.1016/j.biopsych.2019.03.555  0.308
2018 Cerit H, Christensen K, Moondra P, Klibanski A, Goldstein JM, Holsen LM. Divergent associations between ghrelin and neural responsivity to palatable food in hyperphagic and hypophagic depression. Journal of Affective Disorders. 242: 29-38. PMID 30170236 DOI: 10.1016/j.jad.2018.07.088  0.463
2018 Perlo S, Richards CE, Nascimento NF, Kang MS, Ironside M, Ludwick AM, Becerra L, Misra M, Holsen LM, Goldstein JM, Pizzagalli DA. T165. Development of an fMRI-Compatible Acute Stress Paradigm: Optimization and Initial Results Biological Psychiatry. 83: S192. DOI: 10.1016/j.biopsych.2018.02.502  0.445
2017 Plessow F, Marengi DA, Perry SK, Felicione JM, Franklin R, Holmes TM, Holsen LM, Makris N, Deckersbach T, Lawson EA. Effects of Intranasal Oxytocin on the Blood Oxygenation Level-Dependent Signal in Food Motivation and Cognitive Control Pathways in Overweight and Obese Men. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28930284 DOI: 10.1038/npp.2017.226  0.533
2017 Holsen LM, Jackson B. Reward Capacity Predicts Leptin Dynamics During Laboratory-Controlled Eating in Women as a Function of Body Mass Index. Obesity (Silver Spring, Md.). PMID 28722317 DOI: 10.1002/Oby.21930  0.393
2017 Mareckova K, Holsen L, Admon R, Whitfield-Gabrieli S, Seidman LJ, Buka SL, Klibanski A, Goldstein JM. Neural - hormonal responses to negative affective stimuli: Impact of dysphoric mood and sex. Journal of Affective Disorders. 222: 88-97. PMID 28688266 DOI: 10.1016/J.Jad.2017.06.050  0.313
2017 Plessow F, Eddy KT, Baskaran C, Becker K, Deckersbach T, Thomas J, Holsen L, Misra M, Lawson E. 764. Homeostatic and Hedonic Food Motivation in Adolescent Low-Weight Eating Disorders before and after a Standardized Meal Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.831  0.406
2016 Mareckova K, Holsen LM, Admon R, Makris N, Seidman L, Buka S, Whitfield-Gabrieli S, Goldstein JM. Brain activity and connectivity in response to negative affective stimuli: Impact of dysphoric mood and sex across diagnoses. Human Brain Mapping. PMID 27246897 DOI: 10.1002/Hbm.23271  0.394
2016 Mareckova K, Holsen L, Admon R, Whitfield-Gabrieli S, Goldstein JM. ID 515 – Mood dysregulation, sex and sex hormones predict stress response circuitry deficits Clinical Neurophysiology. 127. DOI: 10.1016/J.Clinph.2015.11.382  0.349
2015 Mason SM, Bryn Austin S, Bakalar JL, Boynton-Jarrett R, Field AE, Gooding HC, Holsen LM, Jackson B, Neumark-Sztainer D, Sanchez M, Sogg S, Tanofsky-Kraff M, Rich-Edwards JW. Child Maltreatment's Heavy Toll: The Need for Trauma-Informed Obesity Prevention. American Journal of Preventive Medicine. PMID 26689978 DOI: 10.1016/J.Amepre.2015.11.004  0.305
2015 Goldstein JM, Lancaster K, Longenecker JM, Abbs B, Holsen LM, Cherkerzian S, Whitfield-Gabrieli S, Makris N, Tsuang MT, Buka SL, Seidman LJ, Klibanski A. Sex differences, hormones, and fMRI stress response circuitry deficits in psychoses. Psychiatry Research. 232: 226-36. PMID 25914141 DOI: 10.1016/J.Pscychresns.2015.03.006  0.368
2015 Holsen LM, Goldstein JM. Valuation and cognitive circuitry in anorexia nervosa: disentangling appetite from the effort to obtain a reward. Biological Psychiatry. 77: 604-6. PMID 25766686 DOI: 10.1016/j.biopsych.2015.02.011  0.45
2015 Admon R, Holsen LM, Aizley H, Remington A, Whitfield-Gabrieli S, Goldstein JM, Pizzagalli DA. Striatal Hypersensitivity During Stress in Remitted Individuals with Recurrent Depression. Biological Psychiatry. 78: 67-76. PMID 25483401 DOI: 10.1016/j.biopsych.2014.09.019  0.511
2015 Jacobs EG, Holsen LM, Lancaster K, Makris N, Whitfield-Gabrieli S, Remington A, Weiss B, Buka S, Klibanski A, Goldstein JM. 17β-estradiol differentially regulates stress circuitry activity in healthy and depressed women. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 566-76. PMID 25113601 DOI: 10.1038/Npp.2014.203  0.381
2014 Holsen LM, Lawson EA, Christensen K, Klibanski A, Goldstein JM. Abnormal relationships between the neural response to high- and low-calorie foods and endogenous acylated ghrelin in women with active and weight-recovered anorexia nervosa. Psychiatry Research. 223: 94-103. PMID 24862390 DOI: 10.1016/j.pscychresns.2014.04.015  0.489
2013 Lawson EA, Holsen LM, Desanti R, Santin M, Meenaghan E, Herzog DB, Goldstein JM, Klibanski A. Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food-motivation neurocircuitry in anorexia nervosa. European Journal of Endocrinology / European Federation of Endocrine Societies. 169: 639-47. PMID 23946275 DOI: 10.1530/EJE-13-0433  0.529
2013 Holsen LM, Lancaster K, Klibanski A, Whitfield-Gabrieli S, Cherkerzian S, Buka S, Goldstein JM. HPA-axis hormone modulation of stress response circuitry activity in women with remitted major depression. Neuroscience. 250: 733-42. PMID 23891965 DOI: 10.1016/J.Neuroscience.2013.07.042  0.344
2013 Lennerz BS, Alsop DC, Holsen LM, Stern E, Rojas R, Ebbeling CB, Goldstein JM, Ludwig DS. Effects of dietary glycemic index on brain regions related to reward and craving in men. The American Journal of Clinical Nutrition. 98: 641-7. PMID 23803881 DOI: 10.3945/Ajcn.113.064113  0.392
2013 Lawson EA, Holsen LM, Santin M, DeSanti R, Meenaghan E, Eddy KT, Herzog DB, Goldstein JM, Klibanski A. Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa. The Journal of Clinical Psychiatry. 74: e451-7. PMID 23759466 DOI: 10.4088/JCP.12m08154  0.347
2012 Lawson EA, Holsen LM, Santin M, Meenaghan E, Eddy KT, Becker AE, Herzog DB, Goldstein JM, Klibanski A. Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism. 97: E1898-908. PMID 22872688 DOI: 10.1210/jc.2012-1702  0.512
2012 Holsen LM, Lawson EA, Blum J, Ko E, Makris N, Fazeli PK, Klibanski A, Goldstein JM. Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa. Journal of Psychiatry & Neuroscience : Jpn. 37: 322-32. PMID 22498079 DOI: 10.1503/Jpn.110156  0.474
2012 Holsen LM, Lee JH, Spaeth SB, Ogden LA, Klibanski A, Whitfield-Gabrieli S, Sloan RP, Goldstein JM. Brain hypoactivation, autonomic nervous system dysregulation, and gonadal hormones in depression: a preliminary study. Neuroscience Letters. 514: 57-61. PMID 22395084 DOI: 10.1016/j.neulet.2012.02.056  0.387
2012 Honea RA, Holsen LM, Lepping RJ, Perea R, Butler MG, Brooks WM, Savage CR. The neuroanatomy of genetic subtype differences in Prader-Willi syndrome. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 243-53. PMID 22241551 DOI: 10.1002/ajmg.b.32022  0.606
2012 Holsen LM, Savage CR, Martin LE, Bruce AS, Lepping RJ, Ko E, Brooks WM, Butler MG, Zarcone JR, Goldstein JM. Importance of reward and prefrontal circuitry in hunger and satiety: Prader-Willi syndrome vs simple obesity. International Journal of Obesity (2005). 36: 638-47. PMID 22024642 DOI: 10.1038/Ijo.2011.204  0.704
2012 Bruce JM, Hancock L, Bruce A, Lepping RJ, Martin L, Lundgren JD, Malley S, Holsen LM, Savage CR. Changes in brain activation to food pictures after adjustable gastric banding. Surgery For Obesity and Related Diseases : Official Journal of the American Society For Bariatric Surgery. 8: 602-8. PMID 21996599 DOI: 10.1016/J.Soard.2011.07.006  0.645
2011 Holsen LM, Spaeth SB, Lee JH, Ogden LA, Klibanski A, Whitfield-Gabrieli S, Goldstein JM. Stress response circuitry hypoactivation related to hormonal dysfunction in women with major depression. Journal of Affective Disorders. 131: 379-87. PMID 21183223 DOI: 10.1016/j.jad.2010.11.024  0.415
2010 Bruce AS, Holsen LM, Chambers RJ, Martin LE, Brooks WM, Zarcone JR, Butler MG, Savage CR. Obese children show hyperactivation to food pictures in brain networks linked to motivation, reward and cognitive control. International Journal of Obesity (2005). 34: 1494-500. PMID 20440296 DOI: 10.1038/Ijo.2010.84  0.776
2010 Martin LE, Holsen LM, Chambers RJ, Bruce AS, Brooks WM, Zarcone JR, Butler MG, Savage CR. Neural mechanisms associated with food motivation in obese and healthy weight adults. Obesity (Silver Spring, Md.). 18: 254-60. PMID 19629052 DOI: 10.1038/Oby.2009.220  0.766
2009 Holsen LM, Zarcone JR, Chambers R, Butler MG, Bittel DC, Brooks WM, Thompson TI, Savage CR. Genetic subtype differences in neural circuitry of food motivation in Prader-Willi syndrome. International Journal of Obesity (2005). 33: 273-83. PMID 19048015 DOI: 10.1038/Ijo.2008.255  0.765
2008 Dalton KM, Holsen L, Abbeduto L, Davidson RJ. Brain function and gaze fixation during facial-emotion processing in fragile X and autism. Autism Research : Official Journal of the International Society For Autism Research. 1: 231-9. PMID 19360673 DOI: 10.1002/aur.32  0.666
2008 Holsen LM, Dalton KM, Johnstone T, Davidson RJ. Prefrontal social cognition network dysfunction underlying face encoding and social anxiety in fragile X syndrome. Neuroimage. 43: 592-604. PMID 18778781 DOI: 10.1016/j.neuroimage.2008.08.009  0.641
2007 Zarcone J, Napolitano D, Peterson C, Breidbord J, Ferraioli S, Caruso-Anderson M, Holsen L, Butler MG, Thompson T. The relationship between compulsive behaviour and academic achievement across the three genetic subtypes of Prader-Willi syndrome. Journal of Intellectual Disability Research : Jidr. 51: 478-87. PMID 17493030 DOI: 10.1111/J.1365-2788.2006.00916.X  0.617
2006 Holsen LM, Zarcone JR, Brooks WM, Butler MG, Thompson TI, Ahluwalia JS, Nollen NL, Savage CR. Neural mechanisms underlying hyperphagia in Prader-Willi syndrome. Obesity (Silver Spring, Md.). 14: 1028-37. PMID 16861608 DOI: 10.1038/Oby.2006.118  0.761
2006 Okuyemi KS, Powell JN, Savage CR, Hall SB, Nollen N, Holsen LM, McClernon FJ, Ahluwalia JS. Enhanced cue-elicited brain activation in African American compared with Caucasian smokers: an fMRI study. Addiction Biology. 11: 97-106. PMID 16759342 DOI: 10.1111/J.1369-1600.2006.00007.X  0.535
2006 Young J, Zarcone J, Holsen L, Anderson MC, Hall S, Richman D, Butler MG, Thompson T. A measure of food seeking in individuals with Prader-Willi syndrome. Journal of Intellectual Disability Research : Jidr. 50: 18-24. PMID 16316427 DOI: 10.1111/J.1365-2788.2005.00724.X  0.653
2005 Holsen LM, Zarcone JR, Thompson TI, Brooks WM, Anderson MF, Ahluwalia JS, Nollen NL, Savage CR. Neural mechanisms underlying food motivation in children and adolescents. Neuroimage. 27: 669-76. PMID 15993629 DOI: 10.1016/J.Neuroimage.2005.04.043  0.742
2004 Holsen L, Thompson T. Compulsive behavior and eye blink in Prader-Willi syndrome: neurochemical implications. American Journal of Mental Retardation : Ajmr. 109: 197-207. PMID 15072522 DOI: 10.1352/0895-8017(2004)109<197:CBAEBI>2.0.CO;2  0.563
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