| Year |
Citation |
Score |
| 2023 |
Fu I, Geacintov NE, Broyde S. Differing structures and dynamics of two photolesions portray verification differences by the human XPD helicase. Nucleic Acids Research. 51: 12261-12274. PMID 37933861 DOI: 10.1093/nar/gkad974 |
0.636 |
|
| 2022 |
Sales AH, Zheng V, Kenawy MA, Kakembo M, Zhang L, Shafirovich V, Broyde S, Geacintov NE. Inhibition of RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure-Function Relationships. International Journal of Molecular Sciences. 23. PMID 36555294 DOI: 10.3390/ijms232415654 |
0.66 |
|
| 2022 |
Sales AH, Kolbanovskiy M, Geacintov NE, Chen KM, Sun YW, El-Bayoumy K. Treatment of Human HeLa Cells with Black Raspberry Extracts Enhances the Removal of DNA Lesions by the Nucleotide Excision Repair Mechanism. Antioxidants (Basel, Switzerland). 11. PMID 36358482 DOI: 10.3390/antiox11112110 |
0.455 |
|
| 2022 |
Fu I, Mu H, Geacintov NE, Broyde S. Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair. Nucleic Acids Research. PMID 35713557 DOI: 10.1093/nar/gkac496 |
0.674 |
|
| 2021 |
Fu I, Geacintov NE, Broyde S. Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing. Dna Repair. 107: 103201. PMID 34399316 DOI: 10.1016/j.dnarep.2021.103201 |
0.65 |
|
| 2021 |
Swain U, Friedlander G, Sehrawat U, Sarusi-Portuguez A, Rotkopf R, Ebert C, Paz-Elizur T, Dikstein R, Carell T, Geacintov NE, Livneh Z. TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer. International Journal of Molecular Sciences. 22. PMID 34203408 DOI: 10.3390/ijms22136957 |
0.402 |
|
| 2021 |
Kolbanovskiy M, Aharonoff A, Sales AH, Geacintov NE, Shafirovich V. Recognition and repair of oxidatively generated DNA lesions in plasmid DNA by a facilitated diffusion mechanism. The Biochemical Journal. 478: 2359-2370. PMID 34060590 DOI: 10.1042/BCJ20210095 |
0.485 |
|
| 2021 |
Shafirovich V, Geacintov NE. Excision of Oxidatively Generated Guanine Lesions by Competitive DNA Repair Pathways. International Journal of Molecular Sciences. 22. PMID 33800059 DOI: 10.3390/ijms22052698 |
0.481 |
|
| 2021 |
Kolbanovskiy M, Aharonoff A, Sales AH, Geacintov NE, Shafirovich V. Base and Nucleotide Excision Repair Pathways in DNA Plasmids Harboring Oxidatively Generated Guanine Lesions. Chemical Research in Toxicology. PMID 33405911 DOI: 10.1021/acs.chemrestox.0c00463 |
0.499 |
|
| 2020 |
Feher KM, Kolbanovskiy A, Durandin A, Shim Y, Min JH, Lee YC, Shafirovich V, Mu H, Broyde S, Geacintov NE. The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a missing nucleotide opposite the lesion. Dna Repair. 96: 102985. PMID 33035795 DOI: 10.1016/j.dnarep.2020.102985 |
0.861 |
|
| 2020 |
Kolbanovskiy M, Aharonoff A, Sales AH, Geacintov NE, Shafirovich V. Remarkable Enhancement of Nucleotide Excision Repair of a Bulky Guanine Lesion in a Covalently Closed Circular DNA Plasmid Relative to the Same Linearized Plasmid. Biochemistry. 59: 2842-2848. PMID 32786887 DOI: 10.1021/Acs.Biochem.0C00441 |
0.573 |
|
| 2020 |
Kolbanovskiy M, Shim Y, Min JH, Geacintov NE, Shafirovich V. Inhibition of Excison of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B. Biochemistry. PMID 32302101 DOI: 10.1021/Acs.Biochem.0C00080 |
0.544 |
|
| 2019 |
Cai Y, Geacintov NE, Broyde S. Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Implications for nucleotide excision repair. Dna Repair. 87: 102768. PMID 32018112 DOI: 10.1016/J.Dnarep.2019.102768 |
0.726 |
|
| 2019 |
Ji S, Park D, Kropachev K, Kolbanovskiy M, Fu I, Broyde S, Essawy M, Geacintov NE, Tretyakova NY. 5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not do cause transcription errors in human cells. The Journal of Biological Chemistry. PMID 31597704 DOI: 10.1074/Jbc.Ra119.009834 |
0.668 |
|
| 2019 |
Chatgilialoglu C, Ferreri C, Geacintov NE, Krokidis MG, Liu Y, Masi A, Shafirovich V, Terzidis MA, Tsegay PS. 5',8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance. Cells. 8. PMID 31141888 DOI: 10.3390/Cells8060513 |
0.554 |
|
| 2019 |
Shafirovich V, Kropachev K, Kolbanovskiy M, Geacintov NE. Excision of Oxidatively Generated Guanine Lesions by Competing Base and Nucleotide Excision Repair Mechanisms in Human Cells. Chemical Research in Toxicology. PMID 30688445 DOI: 10.1021/Acs.Chemrestox.8B00411 |
0.521 |
|
| 2018 |
Shafirovich V, Kolbanovskiy M, Kropachev K, Liu Z, Cai Y, Terzidis MA, Masi A, Chatgilialoglu C, Amin S, Dadali A, Broyde S, Geacintov NE. Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes. Biochemistry. PMID 30570250 DOI: 10.1021/Acs.Biochem.8B01066 |
0.729 |
|
| 2018 |
Mu H, Zhang Y, Geacintov NE, Broyde S. Lesion sensing during initial binding by yeast XPC/Rad4: toward predicting resistance to nucleotide excision repair. Chemical Research in Toxicology. PMID 30284444 DOI: 10.1021/Acs.Chemrestox.8B00231 |
0.689 |
|
| 2018 |
Mu H, Geacintov NE, Broyde S, Yeo JE, Schärer OD. Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excision repair. Dna Repair. PMID 30174301 DOI: 10.1016/J.Dnarep.2018.08.005 |
0.679 |
|
| 2018 |
Merta TJ, Geacintov NE, Shafirovich V. Generation of 8-oxo-7,8-dihydroguanine in G-Quadruplexes Models of Human Telomer Sequences by One-Electron Oxidation. Photochemistry and Photobiology. PMID 29679477 DOI: 10.1111/Php.12926 |
0.346 |
|
| 2018 |
Cai Y, Fu I, Geacintov NE, Zhang Y, Broyde S. Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing DNA: Binding of a displaced lesion partner base to the H3 tail for GG-NER recognition. Dna Repair. 65: 73-78. PMID 29631253 DOI: 10.1016/J.Dnarep.2018.02.009 |
0.652 |
|
| 2017 |
Rechkoblit O, Kolbanovskiy A, Landes H, Geacintov NE, Aggarwal AK. Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase. Nature Communications. 8: 965. PMID 29042535 DOI: 10.1038/S41467-017-01013-5 |
0.795 |
|
| 2017 |
Geacintov NE, Broyde S. Repair-Resistant DNA Lesions. Chemical Research in Toxicology. PMID 28750166 DOI: 10.1021/Acs.Chemrestox.7B00128 |
0.697 |
|
| 2017 |
Kolbanovskiy M, Chowdhury MA, Nadkarni A, Broyde S, Geacintov NE, Scicchitano DA, Shafirovich V. The Non-Bulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in vitro. Biochemistry. PMID 28514164 DOI: 10.1021/Acs.Biochem.7B00295 |
0.682 |
|
| 2017 |
Mu H, Geacintov NE, Min JH, Zhang Y, Broyde S. The nucleotide excision repair lesion-recognition protein Rad4 captures a pre-flipped partner base in a benzo[a]pyrene-derived DNA lesion: how structure impacts the binding pathway. Chemical Research in Toxicology. PMID 28460163 DOI: 10.1021/Acs.Chemrestox.7B00074 |
0.712 |
|
| 2017 |
Fu I, Cai Y, Geacintov NE, Zhang Y, Broyde S. Nucleosome histone tail conformation and dynamics: impacts of lysine acetylation and a nearby minor groove benzo[a]pyrene-derived lesion. Biochemistry. PMID 28304160 DOI: 10.1021/Acs.Biochem.6B01208 |
0.683 |
|
| 2016 |
Shafirovich V, Geacintov NE. Removal of oxidatively generated DNA damage by overlapping repair pathways. Free Radical Biology & Medicine. PMID 27818219 DOI: 10.1016/J.Freeradbiomed.2016.10.507 |
0.521 |
|
| 2016 |
Lee YA, Lee YC, Geacintov NE, Shafirovich V. Translesion synthesis past guanine(C8)-thymine(N3) intrastrand cross-links catalyzed by selected A- and Y-family polymerases. Molecular Biosystems. PMID 27102383 DOI: 10.1039/C6Mb00160B |
0.847 |
|
| 2016 |
Purohit NK, Robu M, Shah RG, Geacintov NE, Shah GM. Characterization of the interactions of PARP-1 with UV-damaged DNA in vivo and in vitro. Scientific Reports. 6: 19020. PMID 26753915 DOI: 10.1038/Srep19020 |
0.556 |
|
| 2016 |
Shafirovich V, Kropachev K, Anderson T, Liu Z, Kolbanovskiy M, Martin BD, Sugden K, Shim Y, Chen X, Min JH, Geacintov NE. Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA. The Journal of Biological Chemistry. PMID 26733197 DOI: 10.1074/Jbc.M115.693218 |
0.484 |
|
| 2015 |
Fu I, Cai Y, Zhang Y, Geacintov NE, Broyde S. Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study. Biochemistry. PMID 26709619 DOI: 10.1021/Acs.Biochem.5B01166 |
0.663 |
|
| 2015 |
Nadkarni A, Burns JA, Gandolfi A, Chowdhury MA, Cartularo L, Berens C, Geacintov NE, Scicchitano DA. Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription. The Journal of Biological Chemistry. PMID 26559971 DOI: 10.1074/Jbc.M115.685271 |
0.527 |
|
| 2015 |
Liu Z, Ding S, Kropachev K, Jia L, Amin S, Broyde S, Geacintov NE. Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. Plos One. 10: e0142068. PMID 26512721 DOI: 10.1371/Journal.Pone.0142068 |
0.766 |
|
| 2015 |
Liu Z, Ding S, Kropachev K, Lei J, Amin S, Broyde S, Geacintov NE. Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. Plos One. 10: e0137124. PMID 26340000 DOI: 10.1371/Journal.Pone.0137124 |
0.726 |
|
| 2015 |
Shriber P, Leitner-Dagan Y, Geacintov N, Paz-Elizur T, Livneh Z. DNA sequence context greatly affects the accuracy of bypass across an ultraviolet light 6-4 photoproduct in mammalian cells. Mutation Research. 780: 71-6. PMID 26302378 DOI: 10.1016/J.Mrfmmm.2015.08.002 |
0.57 |
|
| 2015 |
Mu H, Geacintov NE, Zhang Y, Broyde S. Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion. Biochemistry. 54: 5263-7. PMID 26270861 DOI: 10.1021/Acs.Biochem.5B00840 |
0.7 |
|
| 2015 |
Cai Y, Kropachev K, Terzidis MA, Masi A, Chatgilialoglu C, Geacintov NE, Broyde S. Differences in the access of lesions to the nucleotide excision repair machinery in nucleosomes. Biochemistry. PMID 26091016 DOI: 10.1021/Acs.Biochem.5B00564 |
0.676 |
|
| 2015 |
Talhaoui I, Shafirovich V, Liu Z, Saint-Pierre C, Akishev Z, Matkarimov BT, Gasparutto D, Geacintov NE, Saparbaev M. Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways. The Journal of Biological Chemistry. 290: 14610-7. PMID 25903131 DOI: 10.1074/Jbc.M115.647487 |
0.574 |
|
| 2015 |
Cohen IS, Bar C, Paz-Elizur T, Ainbinder E, Leopold K, de Wind N, Geacintov N, Livneh Z. DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes. Nucleic Acids Research. 43: 1637-45. PMID 25589543 DOI: 10.1093/Nar/Gku1398 |
0.548 |
|
| 2014 |
Starostenko LV, Rechkunova NI, Lebedeva NA, Kolbanovskiy A, Geacintov NE, Lavrik OI. Human DNA polymerases catalyze lesion bypass across benzo[a]pyrene-derived DNA adduct clustered with an abasic site. Dna Repair. 24: 1-9. PMID 25460917 DOI: 10.1016/J.Dnarep.2014.10.005 |
0.559 |
|
| 2014 |
Ziv O, Zeisel A, Mirlas-Neisberg N, Swain U, Nevo R, Ben-Chetrit N, Martelli MP, Rossi R, Schiesser S, Canman CE, Carell T, Geacintov NE, Falini B, Domany E, Livneh Z. Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin. Nature Communications. 5: 5437. PMID 25421715 DOI: 10.1038/Ncomms6437 |
0.46 |
|
| 2014 |
Lior-Hoffmann L, Ding S, Geacintov NE, Zhang Y, Broyde S. Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity. Biochemistry. 53: 5683-91. PMID 25148552 DOI: 10.1021/Bi5007964 |
0.686 |
|
| 2014 |
Uvaydov Y, Geacintov NE, Shafirovich V. Generation of guanine-amino acid cross-links by a free radical combination mechanism. Physical Chemistry Chemical Physics : Pccp. 16: 11729-36. PMID 24810398 DOI: 10.1039/C4Cp00675E |
0.332 |
|
| 2014 |
Lee YC, Cai Y, Mu H, Broyde S, Amin S, Chen X, Min JH, Geacintov NE. The relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: is there a correlation? Dna Repair. 19: 55-63. PMID 24784728 DOI: 10.1016/J.Dnarep.2014.03.026 |
0.859 |
|
| 2014 |
Rokhlenko Y, Cadet J, Geacintov NE, Shafirovich V. Mechanistic aspects of hydration of guanine radical cations in DNA. Journal of the American Chemical Society. 136: 5956-62. PMID 24689701 DOI: 10.1021/Ja412471U |
0.49 |
|
| 2014 |
Rodríguez FA, Liu Z, Lin CH, Ding S, Cai Y, Kolbanovskiy A, Kolbanovskiy M, Amin S, Broyde S, Geacintov NE. Nuclear magnetic resonance studies of an N2-guanine adduct derived from the tumorigen dibenzo[a,l]pyrene in DNA: impact of adduct stereochemistry, size, and local DNA sequence on solution conformations. Biochemistry. 53: 1827-41. PMID 24617538 DOI: 10.1021/Bi4017044 |
0.818 |
|
| 2014 |
Kropachev K, Ding S, Terzidis MA, Masi A, Liu Z, Cai Y, Kolbanovskiy M, Chatgilialoglu C, Broyde S, Geacintov NE, Shafirovich V. Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system. Nucleic Acids Research. 42: 5020-32. PMID 24615810 DOI: 10.1093/Nar/Gku162 |
0.708 |
|
| 2014 |
Cadet J, Wagner JR, Shafirovich V, Geacintov NE. One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA. International Journal of Radiation Biology. 90: 423-32. PMID 24369822 DOI: 10.3109/09553002.2013.877176 |
0.459 |
|
| 2014 |
Cai Y, Geacintov NE, Broyde S. Ribonucleotides as nucleotide excision repair substrates. Dna Repair. 13: 55-60. PMID 24290807 DOI: 10.1016/J.Dnarep.2013.10.010 |
0.706 |
|
| 2014 |
Lukashevich OV, Cherepanova NA, Kolbanovsky A, Geacintov NE, Gromova ES. Benzo[a]pyrene-derived DNA lesions decrease DNA methylation by murine methyltransferase DNMT3A2 Moscow University Chemistry Bulletin. 69: 92-96. DOI: 10.3103/S0027131414020059 |
0.551 |
|
| 2014 |
Rodriguez F, Liu Z, Lin C, Ding S, Cai Y, Kolbanovskiy A, Kolbanovskiy M, Amin S, Broyde S, Geacintov N. NMR studies of N2-guanine adducts derived from the tumorigen dibenzo[a,l]pyrene in DNA: Impact of adduct stereochemistry, size, and local DNA structure on solution conformations Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Miv/Pdb |
0.818 |
|
| 2013 |
Krzeminski J, Kropachev K, Reeves D, Kolbanovskiy A, Kolbanovskiy M, Chen KM, Sharma AK, Geacintov N, Amin S, El-Bayoumy K. Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts. Chemical Research in Toxicology. 26: 1746-54. PMID 24112095 DOI: 10.1021/Tx400296X |
0.833 |
|
| 2013 |
Mu H, Kropachev K, Chen Y, Zhang H, Cai Y, Geacintov NE, Broyde S. Role of structural and energetic factors in regulating repair of a bulky DNA lesion with different opposite partner bases. Biochemistry. 52: 5517-21. PMID 23902560 DOI: 10.1021/Bi4009177 |
0.732 |
|
| 2013 |
Cai Y, Zheng H, Ding S, Kropachev K, Schwaid AG, Tang Y, Mu H, Wang S, Geacintov NE, Zhang Y, Broyde S. Free energy profiles of base flipping in intercalative polycyclic aromatic hydrocarbon-damaged DNA duplexes: energetic and structural relationships to nucleotide excision repair susceptibility. Chemical Research in Toxicology. 26: 1115-25. PMID 23758590 DOI: 10.1021/Tx400156A |
0.751 |
|
| 2013 |
Madugundu GS, Wagner JR, Cadet J, Kropachev K, Yun BH, Geacintov NE, Shafirovich V. Generation of guanine-thymine cross-links in human cells by one-electron oxidation mechanisms. Chemical Research in Toxicology. 26: 1031-3. PMID 23734842 DOI: 10.1021/Tx400158G |
0.719 |
|
| 2013 |
Kropachev K, Kolbanovskiy M, Liu Z, Cai Y, Zhang L, Schwaid AG, Kolbanovskiy A, Ding S, Amin S, Broyde S, Geacintov NE. Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not. Chemical Research in Toxicology. 26: 783-93. PMID 23570232 DOI: 10.1021/Tx400080K |
0.708 |
|
| 2013 |
Izhar L, Ziv O, Cohen IS, Geacintov NE, Livneh Z. Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1462-9. PMID 23530190 DOI: 10.1073/Pnas.1216894110 |
0.542 |
|
| 2013 |
Khutsishvili I, Zhang N, Marky LA, Crean C, Patel DJ, Geacintov NE, Shafirovich V. Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions. Biochemistry. 52: 1354-63. PMID 23360616 DOI: 10.1021/Bi301566V |
0.512 |
|
| 2012 |
Tang Y, Liu Z, Ding S, Lin CH, Cai Y, Rodriguez FA, Sayer JM, Jerina DM, Amin S, Broyde S, Geacintov NE. Nuclear magnetic resonance solution structure of an N(2)-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: intercalation from the minor groove with ruptured Watson-Crick base pairing. Biochemistry. 51: 9751-62. PMID 23121427 DOI: 10.1021/Bi3013577 |
0.836 |
|
| 2012 |
Minero AS, Lukashevich OV, Cherepanova NA, Kolbanovskiy A, Geacintov NE, Gromova ES. Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene-modified DNA by fluorescence methods. The Febs Journal. 279: 3965-80. PMID 22913541 DOI: 10.1111/J.1742-4658.2012.08756.X |
0.412 |
|
| 2012 |
Mu H, Kropachev K, Wang L, Zhang L, Kolbanovskiy A, Kolbanovskiy M, Geacintov NE, Broyde S. Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies. Nucleic Acids Research. 40: 9675-90. PMID 22904073 DOI: 10.1093/Nar/Gks788 |
0.682 |
|
| 2012 |
Lior-Hoffmann L, Wang L, Wang S, Geacintov NE, Broyde S, Zhang Y. Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion. Nucleic Acids Research. 40: 9193-205. PMID 22772988 DOI: 10.1093/Nar/Gks653 |
0.671 |
|
| 2012 |
Liu Y, Liu Z, Geacintov NE, Shafirovich V. Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection. Physical Chemistry Chemical Physics : Pccp. 14: 7400-10. PMID 22526555 DOI: 10.1039/C2Cp40759K |
0.469 |
|
| 2012 |
Rokhlenko Y, Geacintov NE, Shafirovich V. Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions. Journal of the American Chemical Society. 134: 4955-62. PMID 22329445 DOI: 10.1021/Ja212186W |
0.315 |
|
| 2012 |
Skosareva LV, Lebedeva NA, Rechkunova NI, Kolbanovskiy A, Geacintov NE, Lavrik OI. Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair. Dna Repair. 11: 367-73. PMID 22317757 DOI: 10.1016/J.Dnarep.2012.01.002 |
0.553 |
|
| 2012 |
Cai Y, Geacintov NE, Broyde S. Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions. Biochemistry. 51: 1486-99. PMID 22242833 DOI: 10.1021/Bi201794X |
0.732 |
|
| 2012 |
Ding S, Kropachev K, Cai Y, Kolbanovskiy M, Durandina SA, Liu Z, Shafirovich V, Broyde S, Geacintov NE. Structural, energetic and dynamic properties of guanine(C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair. Nucleic Acids Research. 40: 2506-17. PMID 22135299 DOI: 10.1093/Nar/Gkr1087 |
0.685 |
|
| 2012 |
Lim KS, Taghizadeh K, Wishnok JS, Babu IR, Shafirovich V, Geacintov NE, Dedon PC. Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation. Chemical Research in Toxicology. 25: 366-73. PMID 22103813 DOI: 10.1021/Tx200422G |
0.377 |
|
| 2011 |
Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. Plos Genetics. 7: e1002262. PMID 21931560 DOI: 10.1371/Journal.Pgen.1002262 |
0.537 |
|
| 2011 |
Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE. Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions. Nucleic Acids Research. 39: 8752-64. PMID 21764772 DOI: 10.1093/Nar/Gkr537 |
0.853 |
|
| 2011 |
Liu Y, Reeves D, Kropachev K, Cai Y, Ding S, Kolbanovskiy M, Kolbanovskiy A, Bolton JL, Broyde S, Van Houten B, Geacintov NE. Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. Dna Repair. 10: 684-96. PMID 21741328 DOI: 10.1016/J.Dnarep.2011.04.020 |
0.853 |
|
| 2011 |
Lee YA, Liu Z, Dedon PC, Geacintov NE, Shafirovich V. Solvent exposure associated with single abasic sites alters the base sequence dependence of oxidation of guanine in DNA in GG sequence contexts. Chembiochem : a European Journal of Chemical Biology. 12: 1731-9. PMID 21656632 DOI: 10.1002/Cbic.201100140 |
0.469 |
|
| 2011 |
Yun BH, Geacintov NE, Shafirovich V. Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide. Chemical Research in Toxicology. 24: 1144-52. PMID 21513308 DOI: 10.1021/Tx200139C |
0.677 |
|
| 2011 |
Cai Y, Ding S, Geacintov NE, Broyde S. Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations. Chemical Research in Toxicology. 24: 522-31. PMID 21361377 DOI: 10.1021/Tx1004002 |
0.623 |
|
| 2011 |
Krzeminski J, Kropachev K, Kolbanovskiy M, Reeves D, Kolbanovskiy A, Yun BH, Geacintov NE, Amin S, El-Bayoumy K. Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene. Chemical Research in Toxicology. 24: 65-72. PMID 21114286 DOI: 10.1021/Tx100284H |
0.836 |
|
| 2011 |
Geacintov NE, Broyde S. Robert Shapiro (1935–2011) Chemical Research in Toxicology. 24: 2055-2056. DOI: 10.1021/Tx200455J |
0.468 |
|
| 2011 |
Broyde S, Wang L, Cai Y, Jia L, Shapiro R, Patel DJ, Geacintov NE. Covalent polycyclic aromatic hydrocarbon-DNA adducts: Carcinogenicity, structure, and function Current Cancer Research. 6: 181-207. DOI: 10.1007/978-1-61737-995-6_9 |
0.689 |
|
| 2010 |
Zheng H, Cai Y, Ding S, Tang Y, Kropachev K, Zhou Y, Wang L, Wang S, Geacintov NE, Zhang Y, Broyde S. Base flipping free energy profiles for damaged and undamaged DNA. Chemical Research in Toxicology. 23: 1868-70. PMID 21090780 DOI: 10.1021/Tx1003613 |
0.762 |
|
| 2010 |
Cai Y, Wang L, Ding S, Schwaid A, Geacintov NE, Broyde S. A bulky DNA lesion derived from a highly potent polycyclic aromatic tumorigen stabilizes nucleosome core particle structure. Biochemistry. 49: 9943-5. PMID 20964331 DOI: 10.1021/Bi101560Y |
0.701 |
|
| 2010 |
Cai Y, Patel DJ, Broyde S, Geacintov NE. Base sequence context effects on nucleotide excision repair. Journal of Nucleic Acids. 2010. PMID 20871811 DOI: 10.4061/2010/174252 |
0.696 |
|
| 2010 |
Shao J, Geacintov NE, Shafirovich V. Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds. The Journal of Physical Chemistry. B. 114: 6685-92. PMID 20415485 DOI: 10.1021/Jp100686J |
0.304 |
|
| 2010 |
Yun BH, Dedon PC, Geacintov NE, Shafirovich V. One-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injection. Photochemistry and Photobiology. 86: 563-70. PMID 20408978 DOI: 10.1111/J.1751-1097.2010.00719.X |
0.714 |
|
| 2010 |
Cai Y, Kropachev K, Xu R, Tang Y, Kolbanovskii M, Kolbanovskii A, Amin S, Patel DJ, Broyde S, Geacintov NE. Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion. Journal of Molecular Biology. 399: 397-409. PMID 20399214 DOI: 10.1016/J.Jmb.2010.04.004 |
0.734 |
|
| 2010 |
Dreij K, Rhrissorrakrai K, Gunsalus KC, Geacintov NE, Scicchitano DA. Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. Carcinogenesis. 31: 1149-57. PMID 20382639 DOI: 10.1093/Carcin/Bgq073 |
0.335 |
|
| 2010 |
Rechkoblit O, Kolbanovskiy A, Malinina L, Geacintov NE, Broyde S, Patel DJ. Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nature Structural & Molecular Biology. 17: 379-88. PMID 20154704 DOI: 10.1038/Nsmb.1771 |
0.822 |
|
| 2010 |
Krzeminski J, Kropachev K, Reeves D, Kolbanovskiy A, Kolbanovskiy M, Geacintov NE, Amin S, El-Bayoumy K. Abstract 3945: Inefficient nucleotide excision repair of the N-(dG-8-yl)-6-AC adduct derived from 6-nitrochrysene, an environmental mammary carcinogen, in human cell extracts Cancer Research. 70: 3945-3945. DOI: 10.1158/1538-7445.Am10-3945 |
0.796 |
|
| 2010 |
Gromova ES, Subach OM, Baskunov VB, Geacintov NE. Impact of carcinogen-DNA adducts on DNA methylation Acs Symposium Series. 1041: 103-116. DOI: 10.1021/bk-2010-1041.ch007 |
0.446 |
|
| 2010 |
Shafirovich V, Geacintov NE. Role of Free Radical Reactions in the Formation of DNA Damage The Chemical Biology of Dna Damage. 81-104. DOI: 10.1002/9783527630110.ch4 |
0.33 |
|
| 2010 |
Broyde S, Wang L, Patel DJ, Geacintov NE. Elucidating Structure-Function Relationships in Bulky DNA Lesions: From Solution Structures to Polymerases The Chemical Biology of Dna Damage. 331-352. DOI: 10.1002/9783527630110.ch14 |
0.62 |
|
| 2010 |
Cai Y, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Broyde S, Patel DJ, Geacintov NE. Recognition and Removal of Bulky DNA Lesions by the Nucleotide Excision Repair System The Chemical Biology of Dna Damage. 261-298. DOI: 10.1002/9783527630110.ch12 |
0.668 |
|
| 2010 |
Geacintov NE, Broyde S. Introduction and Perspectives on the Chemistry and Biology of DNA Damage The Chemical Biology of Dna Damage. 1-20. DOI: 10.1002/9783527630110.ch1 |
0.623 |
|
| 2010 |
Geacintov NE, Broyde S. The Chemical Biology of DNA Damage The Chemical Biology of Dna Damage. 1-449. DOI: 10.1002/9783527630110 |
0.618 |
|
| 2009 |
Ding S, Kolbanovskiy A, Durandin A, Crean C, Shafirovich V, Broyde S, Geacintov NE. Absolute configurations of DNA lesions determined by comparisons of experimental ECD and ORD spectra with DFT calculations. Chirality. 21: E231-41. PMID 19937959 DOI: 10.1002/Chir.20804 |
0.678 |
|
| 2009 |
Crean C, Shao J, Yun BH, Geacintov NE, Shafirovich V. The role of one-electron reduction of lipid hydroperoxides in causing DNA damage. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10634-40. PMID 19746460 DOI: 10.1002/Chem.200900500 |
0.734 |
|
| 2009 |
Crean C, Geacintov NE, Shafirovich V. Methylation of 2'-deoxyguanosine by a free radical mechanism. The Journal of Physical Chemistry. B. 113: 12773-81. PMID 19719172 DOI: 10.1021/Jp903554N |
0.367 |
|
| 2009 |
Jia L, Kropachev K, Ding S, Van Houten B, Geacintov NE, Broyde S. Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. Biochemistry. 48: 8948-57. PMID 19681599 DOI: 10.1021/Bi9010072 |
0.735 |
|
| 2009 |
Adar S, Izhar L, Hendel A, Geacintov N, Livneh Z. Repair of gaps opposite lesions by homologous recombination in mammalian cells. Nucleic Acids Research. 37: 5737-48. PMID 19654238 DOI: 10.1093/Nar/Gkp632 |
0.52 |
|
| 2009 |
Ziv O, Geacintov N, Nakajima S, Yasui A, Livneh Z. DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. Proceedings of the National Academy of Sciences of the United States of America. 106: 11552-7. PMID 19564618 DOI: 10.1073/Pnas.0812548106 |
0.501 |
|
| 2009 |
Zhang N, Ding S, Kolbanovskiy A, Shastry A, Kuzmin VA, Bolton JL, Patel DJ, Broyde S, Geacintov NE. NMR and computational studies of stereoisomeric equine estrogen-derived DNA cytidine adducts in oligonucleotide duplexes: opposite orientations of diastereomeric forms. Biochemistry. 48: 7098-109. PMID 19527068 DOI: 10.1021/Bi9006429 |
0.687 |
|
| 2009 |
Ding S, Jia L, Durandin A, Crean C, Kolbanovskiy A, Shafirovich V, Broyde S, Geacintov NE. Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra. Chemical Research in Toxicology. 22: 1189-93. PMID 19485408 DOI: 10.1021/Tx900107Q |
0.625 |
|
| 2009 |
Rechkoblit O, Malinina L, Cheng Y, Geacintov NE, Broyde S, Patel DJ. Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Structure (London, England : 1993). 17: 725-36. PMID 19446528 DOI: 10.1016/J.Str.2009.03.011 |
0.83 |
|
| 2009 |
Wang Z, Edirisinghe P, Sohn J, Qin Z, Geacintov NE, Thatcher GR, Bolton JL. Development of a liquid chromatography electrospray ionization tandem mass spectrometry method for analysis of stable 4-hydroxyequilenin-DNA adducts in human breast cancer cells. Chemical Research in Toxicology. 22: 1129-36. PMID 19368368 DOI: 10.1021/Tx900063G |
0.41 |
|
| 2009 |
Xu P, Oum L, Lee YC, Geacintov NE, Broyde S. Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. Biochemistry. 48: 4677-90. PMID 19364137 DOI: 10.1021/Bi802363F |
0.836 |
|
| 2009 |
Kropachev K, Kolbanovskii M, Cai Y, Rodríguez F, Kolbanovskii A, Liu Y, Zhang L, Amin S, Patel D, Broyde S, Geacintov NE. The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions. Journal of Molecular Biology. 386: 1193-203. PMID 19162041 DOI: 10.1016/J.Jmb.2008.12.082 |
0.85 |
|
| 2009 |
Shachar S, Ziv O, Avkin S, Adar S, Wittschieben J, Reissner T, Chaney S, Friedberg EC, Wang Z, Carell T, Geacintov N, Livneh Z. Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. The Embo Journal. 28: 383-93. PMID 19153606 DOI: 10.1038/Emboj.2008.281 |
0.484 |
|
| 2009 |
Cai Y, Patel DJ, Geacintov NE, Broyde S. Differential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signals. Journal of Molecular Biology. 385: 30-44. PMID 18948114 DOI: 10.1016/J.Jmb.2008.09.087 |
0.714 |
|
| 2009 |
Shachar S, Ziv O, Avkin S, Adar S, Wittschieben J, Reißner T, Chaney S, Friedberg EC, Wang Z, Carell T, Geacintov N, Livneh Z. Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals The Embo Journal. 28: 992-992. DOI: 10.1038/Emboj.2009.72 |
0.368 |
|
| 2008 |
Margolin Y, Shafirovich V, Geacintov NE, DeMott MS, Dedon PC. DNA sequence context as a determinant of the quantity and chemistry of guanine oxidation produced by hydroxyl radicals and one-electron oxidants. The Journal of Biological Chemistry. 283: 35569-78. PMID 18948263 DOI: 10.1074/Jbc.M806809200 |
0.447 |
|
| 2008 |
Jia L, Geacintov NE, Broyde S. The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucleic Acids Research. 36: 6571-84. PMID 18931375 DOI: 10.1093/Nar/Gkn719 |
0.75 |
|
| 2008 |
Crean C, Geacintov NE, Shafirovich V. Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU). Free Radical Biology & Medicine. 45: 1125-34. PMID 18692567 DOI: 10.1016/J.Freeradbiomed.2008.07.008 |
0.351 |
|
| 2008 |
Ding S, Wang Y, Kolbanovskiy A, Durandin A, Bolton JL, van Breemen RB, Broyde S, Geacintov NE. Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry. Chemical Research in Toxicology. 21: 1739-48. PMID 18680315 DOI: 10.1021/Tx800095F |
0.571 |
|
| 2008 |
Crean C, Lee YA, Yun BH, Geacintov NE, Shafirovich V. Oxidation of guanine by carbonate radicals derived from photolysis of carbonatotetramminecobalt(III) complexes and the pH dependence of intrastrand DNA cross-links mediated by guanine radical reactions. Chembiochem : a European Journal of Chemical Biology. 9: 1985-91. PMID 18655084 DOI: 10.1002/Cbic.200800105 |
0.657 |
|
| 2008 |
Hendel A, Ziv O, Gueranger Q, Geacintov N, Livneh Z. Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta. Dna Repair. 7: 1636-46. PMID 18634905 DOI: 10.1016/J.Dnarep.2008.06.008 |
0.451 |
|
| 2008 |
Izhar L, Goldsmith M, Dahan R, Geacintov N, Lloyd RG, Livneh Z. Analysis of strand transfer and template switching mechanisms of DNA gap repair by homologous recombination in Escherichia coli: predominance of strand transfer. Journal of Molecular Biology. 381: 803-9. PMID 18585391 DOI: 10.1016/J.Jmb.2008.06.031 |
0.484 |
|
| 2008 |
Dimitri A, Jia L, Shafirovich V, Geacintov NE, Broyde S, Scicchitano DA. Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase. Dna Repair. 7: 1276-88. PMID 18555749 DOI: 10.1016/J.Dnarep.2008.04.007 |
0.711 |
|
| 2008 |
Ding S, Shapiro R, Cai Y, Geacintov NE, Broyde S. Conformational properties of equilenin-DNA adducts: stereoisomer and base effects. Chemical Research in Toxicology. 21: 1064-73. PMID 18416538 DOI: 10.1021/Tx800010U |
0.734 |
|
| 2008 |
Broyde S, Wang L, Rechkoblit O, Geacintov NE, Patel DJ. Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Trends in Biochemical Sciences. 33: 209-19. PMID 18407502 DOI: 10.1016/J.Tibs.2008.02.004 |
0.839 |
|
| 2008 |
Xu P, Oum L, Geacintov NE, Broyde S. Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. Biochemistry. 47: 2701-9. PMID 18260644 DOI: 10.1021/Bi701839Q |
0.836 |
|
| 2008 |
Lee YA, Durandin A, Dedon PC, Geacintov NE, Shafirovich V. Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesions. The Journal of Physical Chemistry. B. 112: 1834-44. PMID 18211057 DOI: 10.1021/Jp076777X |
0.415 |
|
| 2008 |
Crean C, Geacintov NE, Shafirovich V. Pathways of arachidonic acid peroxyl radical reactions and product formation with guanine radicals. Chemical Research in Toxicology. 21: 358-73. PMID 18159932 DOI: 10.1021/Tx700281E |
0.303 |
|
| 2008 |
Crean C, Uvaydov Y, Geacintov NE, Shafirovich V. Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines. Nucleic Acids Research. 36: 742-55. PMID 18084033 DOI: 10.1093/Nar/Gkm1092 |
0.409 |
|
| 2008 |
Broyde S, Wang L, Zhang L, Rechkoblit O, Geacintov NE, Patel DJ. DNA adduct structure-function relationships: comparing solution with polymerase structures. Chemical Research in Toxicology. 21: 45-52. PMID 18052109 DOI: 10.1021/Tx700193X |
0.81 |
|
| 2008 |
Shafirovich V, Dourandin A, Luneva NP, Singh C, Kirigin F, Geacintov NE. Multiphoton Near-Infrared Femtosecond Laser Pulse-Induced DNA Damage With and Without the Photosensitizer Proflavine Photochemistry and Photobiology. 69: 265-274. DOI: 10.1111/J.1751-1097.1999.Tb03285.X |
0.409 |
|
| 2007 |
Cai Y, Patel DJ, Geacintov NE, Broyde S. Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair. Journal of Molecular Biology. 374: 292-305. PMID 17942115 DOI: 10.1016/J.Jmb.2007.09.034 |
0.735 |
|
| 2007 |
Yun BH, Lee YA, Kim SK, Kuzmin V, Kolbanovskiy A, Dedon PC, Geacintov NE, Shafirovich V. Photosensitized oxidative DNA damage: from hole injection to chemical product formation and strand cleavage. Journal of the American Chemical Society. 129: 9321-32. PMID 17616188 DOI: 10.1021/Ja066954S |
0.737 |
|
| 2007 |
Xu P, Oum L, Beese LS, Geacintov NE, Broyde S. Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Nucleic Acids Research. 35: 4275-88. PMID 17576677 DOI: 10.1093/Nar/Gkm416 |
0.858 |
|
| 2007 |
Mocquet V, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Tapias A, Cai Y, Broyde S, Geacintov NE, Egly JM. The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions. The Embo Journal. 26: 2923-32. PMID 17525733 DOI: 10.1038/Sj.Emboj.7601730 |
0.72 |
|
| 2007 |
Ruan Q, Liu T, Kolbanovskiy A, Liu Y, Ren J, Skorvaga M, Zou Y, Lader J, Malkani B, Amin S, Van Houten B, Geacintov NE. Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry. 46: 7006-15. PMID 17506530 DOI: 10.1021/Bi700294K |
0.752 |
|
| 2007 |
Jia L, Shafirovich V, Geacintov NE, Broyde S. Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies. Biochemistry. 46: 5305-14. PMID 17432829 DOI: 10.1021/Bi062269M |
0.711 |
|
| 2007 |
Subach OM, Maltseva DV, Shastry A, Kolbanovskiy A, Klimasauskas S, Geacintov NE, Gromova ES. The stereochemistry of benzo[a]pyrene-2'-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases. The Febs Journal. 274: 2121-34. PMID 17388812 DOI: 10.1111/J.1742-4658.2007.05754.X |
0.523 |
|
| 2007 |
Lee YA, Yun BH, Kim SK, Margolin Y, Dedon PC, Geacintov NE, Shafirovich V. Mechanisms of oxidation of guanine in DNA by carbonate radical anion, a decomposition product of nitrosoperoxycarbonate. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 4571-81. PMID 17335089 DOI: 10.1002/Chem.200601434 |
0.689 |
|
| 2007 |
Rodríguez FA, Cai Y, Lin C, Tang Y, Kolbanovskiy A, Amin S, Patel DJ, Broyde S, Geacintov NE. Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context. Nucleic Acids Research. 35: 1555-68. PMID 17287290 DOI: 10.1093/Nar/Gkm022 |
0.853 |
|
| 2007 |
Ding S, Shapiro R, Geacintov NE, Broyde S. 4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. Biochemistry. 46: 182-91. PMID 17198388 DOI: 10.1021/Bi061652O |
0.77 |
|
| 2007 |
Perlow-Poehnelt RA, Likhterov I, Wang L, Scicchitano DA, Geacintov NE, Broyde S. Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase. The Journal of Biological Chemistry. 282: 1397-408. PMID 17090533 DOI: 10.1074/Jbc.M606769200 |
0.704 |
|
| 2007 |
Yan S, Wu M, Patel DJ, Geacintov NE, Broyde S. Erratum: Actin polymerization serves as a membrane domain switch in model lipid bilayers (Biophysical Journal (2006) 91, (4064-4070)) Biophysical Journal. 92. DOI: 10.1529/Biophysj.106.0900150 |
0.471 |
|
| 2006 |
Durandin A, Jia L, Crean C, Kolbanovskiy A, Ding S, Shafirovich V, Broyde S, Geacintov NE. Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods. Chemical Research in Toxicology. 19: 908-13. PMID 16841958 DOI: 10.1021/Tx060078E |
0.646 |
|
| 2006 |
Margolin Y, Cloutier JF, Shafirovich V, Geacintov NE, Dedon PC. Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nature Chemical Biology. 2: 365-6. PMID 16751762 DOI: 10.1038/Nchembio796 |
0.399 |
|
| 2006 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. Biochemistry. 45: 6644-55. PMID 16716075 DOI: 10.1021/Bi0601757 |
0.776 |
|
| 2006 |
Subach OM, Baskunov VB, Darii MV, Maltseva DV, Alexandrov DA, Kirsanova OV, Kolbanovskiy A, Kolbanovskiy M, Johnson F, Bonala R, Geacintov NE, Gromova ES. Impact of benzo[a]pyrene-2'-deoxyguanosine lesions on methylation of DNA by SssI and HhaI DNA methyltransferases. Biochemistry. 45: 6142-59. PMID 16681387 DOI: 10.1021/Bi0511639 |
0.518 |
|
| 2006 |
Avkin S, Sevilya Z, Toube L, Geacintov N, Chaney SG, Oren M, Livneh Z. p53 and p21 regulate error-prone DNA repair to yield a lower mutation load. Molecular Cell. 22: 407-13. PMID 16678112 DOI: 10.1016/J.Molcel.2006.03.022 |
0.471 |
|
| 2006 |
Zhao B, Wang J, Geacintov NE, Wang Z. Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Nucleic Acids Research. 34: 417-25. PMID 16415180 DOI: 10.1093/Nar/Gkj446 |
0.486 |
|
| 2006 |
Rechkoblit O, Malinina L, Cheng Y, Kuryavyi V, Broyde S, Geacintov NE, Patel DJ. Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Plos Biology. 4: e11. PMID 16379496 DOI: 10.1371/Journal.Pbio.0040011 |
0.843 |
|
| 2006 |
Zhao B, Wang J, Geacintov NE, Wang Z. Erratum: Polη, Polζ and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells (Nucleic Acids Research (2006) vol. 34 (417-425)) Nucleic Acids Research. 34. DOI: 10.1093/Nar/Gkl056 |
0.437 |
|
| 2005 |
Kolbanovskiy A, Kuzmin V, Shastry A, Kolbanovskaya M, Chen D, Chang M, Bolton JL, Geacintov NE. Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin. Chemical Research in Toxicology. 18: 1737-47. PMID 16300383 DOI: 10.1021/Tx050190X |
0.613 |
|
| 2005 |
Ding S, Shapiro R, Geacintov NE, Broyde S. Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamics. Biochemistry. 44: 14565-76. PMID 16262256 DOI: 10.1021/Bi051090T |
0.762 |
|
| 2005 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. Biochemistry. 44: 13342-53. PMID 16201759 DOI: 10.1021/Bi050790V |
0.784 |
|
| 2005 |
Suzuki N, Yasui M, Geacintov NE, Shafirovich V, Shibutani S. Miscoding events during DNA synthesis past the nitration-damaged base 8-nitroguanine. Biochemistry. 44: 9238-45. PMID 15966748 DOI: 10.1021/Bi050276P |
0.523 |
|
| 2005 |
Jia L, Shafirovich V, Shapiro R, Geacintov NE, Broyde S. Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications. Biochemistry. 44: 6043-51. PMID 15835893 DOI: 10.1021/Bi0473657 |
0.777 |
|
| 2005 |
Wang L, Wu M, Yan SF, Patel DJ, Geacintov NE, Broyde S. Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations. Chemical Research in Toxicology. 18: 441-56. PMID 15777084 DOI: 10.1021/Tx049786V |
0.63 |
|
| 2005 |
Misiaszek R, Crean C, Geacintov NE, Shafirovich V. Combination of nitrogen dioxide radicals with 8-oxo-7,8-dihydroguanine and guanine radicals in DNA: oxidation and nitration end-products. Journal of the American Chemical Society. 127: 2191-200. PMID 15713097 DOI: 10.1021/Ja044390R |
0.414 |
|
| 2005 |
Zhang N, Lin C, Huang X, Kolbanovskiy A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. Journal of Molecular Biology. 346: 951-65. PMID 15701509 DOI: 10.1016/J.Jmb.2004.12.027 |
0.757 |
|
| 2005 |
Baskunov VB, Subach FV, Kolbanovskiy A, Kolbanovskiy M, Eremin SA, Johnson F, Bonala R, Geacintov NE, Gromova ES. Effects of benzo[a]pyrene-deoxyguanosine lesions on DNA methylation catalyzed by EcoRII DNA methyltransferase and on DNA cleavage effected by EcoRII restriction endonuclease. Biochemistry. 44: 1054-66. PMID 15654762 DOI: 10.1021/Bi048130Y |
0.559 |
|
| 2005 |
Misiaszek R, Uvaydov Y, Crean C, Geacintov NE, Shafirovich V. Combination reactions of superoxide with 8-Oxo-7,8-dihydroguanine radicals in DNA: kinetics and end products. The Journal of Biological Chemistry. 280: 6293-300. PMID 15590679 DOI: 10.1074/Jbc.M412253200 |
0.427 |
|
| 2005 |
Hsu GW, Huang X, Luneva NP, Geacintov NE, Beese LS. Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. The Journal of Biological Chemistry. 280: 3764-70. PMID 15548515 DOI: 10.1074/Jbc.M411276200 |
0.707 |
|
| 2005 |
Liu Y, Yang Z, Utzat CD, Liu Y, Geacintov NE, Basu AK, Zou Y. Interactions of human replication protein A with single-stranded DNA adducts. The Biochemical Journal. 385: 519-26. PMID 15362978 DOI: 10.1042/Bj20041151 |
0.545 |
|
| 2005 |
Naegeli H, Geacintov NE. Mechanisms of repair of polycyclic aromatic hydrocarbon-induced DNA damage The Carcinogenic Effects of Polycyclic Aromatic Hydrocarbons. 211-258. DOI: 10.1142/9781860949333_0006 |
0.367 |
|
| 2004 |
Avkin S, Goldsmith M, Velasco-Miguel S, Geacintov N, Friedberg EC, Livneh Z. Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa. The Journal of Biological Chemistry. 279: 53298-305. PMID 15475561 DOI: 10.1074/Jbc.M409155200 |
0.524 |
|
| 2004 |
Wu M, Yan SF, Tan J, Patel DJ, Geacintov NE, Broyde S. Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene. Frontiers in Bioscience : a Journal and Virtual Library. 9: 2807-18. PMID 15353316 DOI: 10.2741/1438 |
0.673 |
|
| 2004 |
Perlow-Poehnelt RA, Likhterov I, Scicchitano DA, Geacintov NE, Broyde S. The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches. The Journal of Biological Chemistry. 279: 36951-61. PMID 15210693 DOI: 10.1074/Jbc.M404332200 |
0.726 |
|
| 2004 |
Yan SF, Wu M, Geacintov NE, Broyde S. Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template. Biochemistry. 43: 7750-65. PMID 15196018 DOI: 10.1021/Bi0499516 |
0.729 |
|
| 2004 |
Misiaszek R, Crean C, Joffe A, Geacintov NE, Shafirovich V. Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping. The Journal of Biological Chemistry. 279: 32106-15. PMID 15152004 DOI: 10.1074/Jbc.M313904200 |
0.422 |
|
| 2004 |
Zou Y, Ma H, Minko IG, Shell SM, Yang Z, Qu Y, Xu Y, Geacintov NE, Lloyd RS. DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair. Biochemistry. 43: 4196-205. PMID 15065863 DOI: 10.1021/Bi035992A |
0.526 |
|
| 2004 |
Zou Y, Ma H, Minko I, Shell SM, Yang ZG, Qu Y, Xu Y, Geacintov NE, Lloyd R(. Erratum: DNA damage recognition of mutated forms of UvrB proteins in nucleotide excision repair (Biochemistry (April 13, 2004) 43, 14 (4196-4205)) Biochemistry. 43. DOI: 10.1021/Bi0400251 |
0.447 |
|
| 2003 |
Joffe A, Geacintov NE, Shafirovich V. DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions. Chemical Research in Toxicology. 16: 1528-38. PMID 14680366 DOI: 10.1021/Tx034142T |
0.427 |
|
| 2003 |
Zou Y, Shell SM, Utzat CD, Luo C, Yang Z, Geacintov NE, Basu AK. Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. Biochemistry. 42: 12654-61. PMID 14580212 DOI: 10.1021/Bi034446E |
0.6 |
|
| 2003 |
Schinecker TM, Perlow RA, Broyde S, Geacintov NE, Scicchitano DA. Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences. Nucleic Acids Research. 31: 6004-15. PMID 14530448 DOI: 10.1093/Nar/Gkg771 |
0.677 |
|
| 2003 |
Xie Z, Braithwaite E, Guo D, Zhao B, Geacintov NE, Wang Z. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta. Biochemistry. 42: 11253-62. PMID 14503875 DOI: 10.1021/Bi0346704 |
0.545 |
|
| 2003 |
Joffe A, Mock S, Yun BH, Kolbanovskiy A, Geacintov NE, Shafirovich V. Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides. Chemical Research in Toxicology. 16: 966-73. PMID 12924924 DOI: 10.1021/Tx025578W |
0.708 |
|
| 2003 |
Ding S, Shapiro R, Geacintov NE, Broyde S. Conformations of stereoisomeric base adducts to 4-hydroxyequilenin. Chemical Research in Toxicology. 16: 695-707. PMID 12807352 DOI: 10.1021/Tx0340246 |
0.747 |
|
| 2003 |
Yan S, Wu M, Patel DJ, Geacintov NE, Broyde S. Simulating structural and thermodynamic properties of carcinogen-damaged DNA. Biophysical Journal. 84: 2137-48. PMID 12668423 DOI: 10.1016/S0006-3495(03)75020-6 |
0.651 |
|
| 2003 |
Perlow RA, Schinecker TM, Kim SJ, Geacintov NE, Scicchitano DA. Construction and purification of site-specifically modified DNA templates for transcription assays. Nucleic Acids Research. 31: e40. PMID 12655028 DOI: 10.1093/Nar/Gng040 |
0.537 |
|
| 2003 |
Muheim R, Buterin T, Colgate KC, Kolbanovsij A, Geacintov NE, Naegeli H. Modulation of human nucleotide excision repair by 5-methylcytosines. Biochemistry. 42: 3247-54. PMID 12641456 DOI: 10.1021/Bi0268504 |
0.837 |
|
| 2003 |
Huang X, Kolbanovskiy A, Wu X, Zhang Y, Wang Z, Zhuang P, Amin S, Geacintov NE. Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa. Biochemistry. 42: 2456-66. PMID 12600213 DOI: 10.1021/Bi026912Q |
0.729 |
|
| 2003 |
Yan S, Wu M, Buterin T, Naegeli H, Geacintov NE, Broyde S. Role of base sequence context in conformational equilibria and nucleotide excision repair of benzo[a]pyrene diol epoxide-adenine adducts. Biochemistry. 42: 2339-54. PMID 12600201 DOI: 10.1021/Bi0270081 |
0.601 |
|
| 2003 |
Shafirovich V, Singh C, Geacintov NE. Photoinduced Oxidative DNA Damage Revealed by an Agarose Gel Nicking Assay: A Biophysical Chemistry Laboratory Experiment Journal of Chemical Education. 80: 1297-1299. DOI: 10.1021/Ed080P1297 |
0.488 |
|
| 2002 |
Zhang Y, Wu X, Guo D, Rechkoblit O, Geacintov NE, Wang Z. Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa. Mutation Research. 510: 23-35. PMID 12459440 DOI: 10.1016/S0027-5107(02)00249-X |
0.815 |
|
| 2002 |
Geacintov NE, Broyde S, Buterin T, Naegeli H, Wu M, Yan S, Patel DJ. Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery. Biopolymers. 65: 202-10. PMID 12228925 DOI: 10.1002/Bip.10239 |
0.715 |
|
| 2002 |
Zhang Y, Wu X, Guo D, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z. Lesion bypass activities of human DNA polymerase mu. The Journal of Biological Chemistry. 277: 44582-7. PMID 12228225 DOI: 10.1074/Jbc.M207297200 |
0.789 |
|
| 2002 |
Buterin T, Hess MT, Gunz D, Geacintov NE, Mullenders LH, Naegeli H. Trapping of DNA nucleotide excision repair factors by nonrepairable carcinogen adducts. Cancer Research. 62: 4229-35. PMID 12154024 DOI: 10.5167/Uzh-14526 |
0.539 |
|
| 2002 |
Wu M, Yan S, Patel DJ, Geacintov NE, Broyde S. Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability. Nucleic Acids Research. 30: 3422-32. PMID 12140327 DOI: 10.1093/Nar/Gkf427 |
0.632 |
|
| 2002 |
Perlow RA, Kolbanovskii A, Hingerty BE, Geacintov NE, Broyde S, Scicchitano DA. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner. Journal of Molecular Biology. 321: 29-47. PMID 12139931 DOI: 10.1016/S0022-2836(02)00593-4 |
0.734 |
|
| 2002 |
Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE. trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. The Journal of Biological Chemistry. 277: 30488-94. PMID 12063247 DOI: 10.1074/Jbc.M201167200 |
0.811 |
|
| 2002 |
Yan S, Wu M, Ding S, Geacintov NE, Broyde S. Conformational analysis of a 4-hydroxyequilenin Guanine adduct using density functional theory. Chemical Research in Toxicology. 15: 648-53. PMID 12018985 DOI: 10.1021/Tx0101797 |
0.596 |
|
| 2002 |
Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S. Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry. 41: 6100-6. PMID 11994005 DOI: 10.1021/Bi020049C |
0.563 |
|
| 2002 |
Shafirovich V, Mock S, Kolbanovskiy A, Geacintov NE. Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide Chemical Research in Toxicology. 15: 591-597. PMID 11952346 DOI: 10.1021/Tx015593L |
0.448 |
|
| 2002 |
Zhang Y, Wu X, Rechkoblit O, Geacintov NE, Taylor JS, Wang Z. Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Nucleic Acids Research. 30: 1630-8. PMID 11917024 DOI: 10.1093/Nar/30.7.1630 |
0.829 |
|
| 2002 |
Huang X, Colgate KC, Kolbanovskiy A, Amin S, Geacintov NE. Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context. Chemical Research in Toxicology. 15: 438-44. PMID 11896693 DOI: 10.1021/Tx015588H |
0.823 |
|
| 2002 |
Ruan Q, Kolbanovskiy A, Zhuang P, Chen J, Krzeminski J, Amin S, Geacintov NE. Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes. Chemical Research in Toxicology. 15: 249-61. PMID 11849052 DOI: 10.1021/Tx010157K |
0.738 |
|
| 2002 |
Huang W, Amin S, Geacintov NE. Fluorescence characteristics of site-specific and stereochemically distinct benzo[a]pyrene diol epoxide-DNA adducts as probes of adduct conformation. Chemical Research in Toxicology. 15: 118-26. PMID 11849037 DOI: 10.1021/Tx010135Y |
0.594 |
|
| 2001 |
Wu M, Yan S, Patel DJ, Geacintov NE, Broyde S. Cyclohexene ring and Fjord region twist inversion in stereoisomeric DNA adducts of enantiomeric benzo[c]phenanthrene diol epoxides. Chemical Research in Toxicology. 14: 1629-42. PMID 11743746 DOI: 10.1021/Tx010152N |
0.625 |
|
| 2001 |
Ruan Q, Zhuang P, Li S, Perlow R, Srinivasan AR, Lu XJ, Broyde S, Olson WK, Geacintov NE. Base sequence effects in bending induced by bulky carcinogen-DNA adducts: experimental and computational analysis. Biochemistry. 40: 10458-72. PMID 11523987 DOI: 10.1021/Bi002643X |
0.825 |
|
| 2001 |
Yan S, Shapiro R, Geacintov NE, Broyde S. Stereochemical, structural, and thermodynamic origins of stability differences between stereoisomeric benzo[a]pyrene diol epoxide deoxyadenosine adducts in a DNA mutational hot spot sequence. Journal of the American Chemical Society. 123: 7054-66. PMID 11459484 DOI: 10.1021/Ja0043035 |
0.725 |
|
| 2001 |
Zhuang P, Kolbanovskiy A, Amin S, Geacintov NE. Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. Biochemistry. 40: 6660-9. PMID 11380261 DOI: 10.1021/Bi010005O |
0.642 |
|
| 2001 |
Rechkoblit O, Krzeminsky J, Amin S, Jernström B, Louneva N, Geacintov NE. Influence of bulky polynuclear carcinogen lesions in a TATA promoter sequence on TATA binding protein-DNA complex formation. Biochemistry. 40: 5622-32. PMID 11341827 DOI: 10.1021/Bi002543R |
0.813 |
|
| 2001 |
Shafirovich V, Dourandin A, Huang W, Geacintov NE. The carbonate radical is a site-selective oxidizing agent of guanine in double-stranded oligonucleotides. The Journal of Biological Chemistry. 276: 24621-6. PMID 11320091 DOI: 10.1074/Jbc.M101131200 |
0.544 |
|
| 2001 |
Roth RB, Amin S, Geacintov NE, Scicchitano DA. Bacteriophage T7 RNA polymerase transcription elongation is inhibited by site-specific, stereospecific benzo[c]phenanthrene diol epoxide DNA lesions Biochemistry. 40: 5200-5207. PMID 11318642 DOI: 10.1021/Bi0024355 |
0.525 |
|
| 2001 |
Shafirovich V, Cadet J, Gasparutto D, Dourandin A, Geacintov NE. Nitrogen dioxide as an oxidizing agent of 8-oxo-7,8-dihydro-2′-deoxyguanosine but not of 2′-deoxyguanosine Chemical Research in Toxicology. 14: 233-241. PMID 11258973 DOI: 10.1021/Tx000204T |
0.311 |
|
| 2001 |
Zou Y, Luo C, Geacintov NE. Hierarchy of DNA damage recognition in Escherichia coli nucleotide excision repair Biochemistry. 40: 2923-2931. PMID 11258904 DOI: 10.1021/Bi001504C |
0.572 |
|
| 2001 |
Lin CH, Huang X, Kolbanovskii A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. Journal of Molecular Biology. 306: 1059-80. PMID 11237618 DOI: 10.1006/Jmbi.2001.4425 |
0.749 |
|
| 2001 |
Shafirovich V, Dourandin A, Geacintov NE. Proton-coupled electron-transfer reactions at a distance in DNA duplexes: Kinetic deuterium isotope effect Journal of Physical Chemistry B. 105: 8431-8435. DOI: 10.1021/Jp0044734 |
0.338 |
|
| 2001 |
Shafirovich V, Cadet J, Gasparutto D, Dourandin A, Huang W, Geacintov NE. Direct Spectroscopic Observation of 8-Oxo-7,8-dihydro-2‘-deoxyguanosine Radicals in Double-Stranded DNA Generated by One-Electron Oxidation at a Distance by 2-Aminopurine Radicals The Journal of Physical Chemistry B. 105: 586-592. DOI: 10.1021/Jp0029055 |
0.526 |
|
| 2000 |
Zhang Y, Yuan F, Wu X, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z. Error-prone lesion bypass by human DNA polymerase eta. Nucleic Acids Research. 28: 4717-24. PMID 11095682 DOI: 10.1093/Nar/28.23.4717 |
0.813 |
|
| 2000 |
Lenne-Samuel N, Janel-Bintz R, Kolbanovskiy A, Geacintov NE, Fuchs RP. The processing of a Benzo(a)pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli. Molecular Microbiology. 38: 299-307. PMID 11069656 DOI: 10.1046/J.1365-2958.2000.02116.X |
0.56 |
|
| 2000 |
Zhang Y, Yuan F, Wu X, Wang M, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Research. 28: 4138-46. PMID 11058110 DOI: 10.1093/Nar/28.21.4138 |
0.799 |
|
| 2000 |
Hoare S, Zou Y, Purohit V, Krishnasamy R, Skorvaga M, Van Houten B, Geacintov NE, Basu AK. Differential incision of bulky carcinogen-DNA adducts by the UvrABC nuclease: comparison of incision rates and the interactions of Uvr subunits with lesions of different structures. Biochemistry. 39: 12252-61. PMID 11015204 DOI: 10.1021/Bi0013187 |
0.556 |
|
| 2000 |
Tan J, Geacintov NE, Broyde S. Conformational determinants of structures in stereoisomeric cis-opened anti-benzo[a]pyrene diol epoxide adducts to adenine in DNA. Chemical Research in Toxicology. 13: 811-22. PMID 10995253 DOI: 10.1021/Tx000094Q |
0.623 |
|
| 2000 |
Shimotakahara S, Gorin A, Kolbanovskiy A, Kettani A, Hingerty BE, Amin S, Broyde S, Geacintov N, Patel DJ. Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove. Journal of Molecular Biology. 302: 377-93. PMID 10970740 DOI: 10.1006/Jmbi.2000.4071 |
0.672 |
|
| 2000 |
Buterin T, Hess MT, Luneva N, Geacintov NE, Amin S, Kroth H, Seidel A, Naegeli H. Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots. Cancer Research. 60: 1849-1856. DOI: 10.5167/Uzh-35868 |
0.491 |
|
| 2000 |
Tsao H, Rechkoblit O, Amin S, Geacintov NE. Impact of site-specific benzo[a]pyrene diol epoxide-dg lesions at or near single/double-strand DNA junctions on DNA bending Polycyclic Aromatic Compounds. 21: 1-10. DOI: 10.1080/10406630008028518 |
0.826 |
|
| 2000 |
Shafirovich V, Dourandin A, Huang W, Luneva NP, Geacintov NE. Electron transfer at a distance induced by site-selective photoionization of 2-aminopurine in oligonucleotides and investigated by transient absorption techniques Physical Chemistry Chemical Physics. 2: 4399-4408. DOI: 10.1039/B004896H |
0.449 |
|
| 2000 |
Kuzmin VA, Dourandin A, Shafirovich V, Geacintov NE. Proton-coupled electron transfer in the oxidation of guanines by an aromatic pyrenyl radical cation in aqueous solutions Physical Chemistry Chemical Physics. 2: 1531-1535. DOI: 10.1039/B000212G |
0.312 |
|
| 2000 |
Tan J, Geacintov NE, Broyde S. Principles governing conformations in stereoisomeric adducts of Bay region benzo[a]pyrene diol epoxides to adenine in DNA: Steric and hydrophobic effects are dominant Journal of the American Chemical Society. 122: 3021-3032. DOI: 10.1021/Ja993624H |
0.639 |
|
| 1999 |
Wu J, Gu L, Wang H, Geacintov NE, Li GM. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis Molecular and Cellular Biology. 19: 8292-8301. PMID 10567554 DOI: 10.1128/Mcb.19.12.8292 |
0.455 |
|
| 1999 |
Rechkoblit O, Amin S, Geacintov NE. Primer length dependence of binding of DNA polymerase I Klenow fragment to template-primer complexes containing site-specific bulky lesions Biochemistry. 38: 11834-11843. PMID 10512640 DOI: 10.1021/Bi990614K |
0.813 |
|
| 1999 |
Suri AK, Mao B, Amin S, Geacintov NE, Patel DJ. Solution conformation of the (+)-trans-anti-benzo[g]chrysene-dA adduct opposite dT in a DNA duplex. Journal of Molecular Biology. 292: 289-307. PMID 10493876 DOI: 10.1006/Jmbi.1999.2974 |
0.44 |
|
| 1999 |
Mao B, Gu Z, Gorin A, Chen J, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex. Biochemistry. 38: 10831-42. PMID 10451380 DOI: 10.1021/Bi991212F |
0.672 |
|
| 1999 |
Xie XM, Geacintov NE, Broyde S. Origins of conformational differences between cis and trans DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides. Chemical Research in Toxicology. 12: 597-609. PMID 10409399 DOI: 10.1021/Tx990021A |
0.616 |
|
| 1999 |
Xie XM, Geacintov NE, Broyde S. Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials. Biochemistry. 38: 2956-68. PMID 10074348 DOI: 10.1021/Bi9825605 |
0.639 |
|
| 1999 |
Shukla R, Geacintov NE, Loechler EL. The major, N2-dG adduct of (+)-anti-B[a]PDE induces G→A mutations in a 5'-AGA-3' sequence context Carcinogenesis. 20: 261-268. PMID 10069463 DOI: 10.1093/Carcin/20.2.261 |
0.33 |
|
| 1999 |
Ni J, Liu T, Kolbanovskiy A, Krzeminski J, Amin S, Geacintov NE. Mass spectrometric sequencing of site-specific carcinogen-modified oligodeoxyribonucleotides containing bulky benzo[a]pyrene diol epoxide-deoxyguanosyl adducts. Analytical Biochemistry. 264: 222-9. PMID 9866687 DOI: 10.1006/Abio.1998.2835 |
0.389 |
|
| 1999 |
Krzeminski J, Ni J, Zhuang P, Luneva N, Amin S, Geacintov NE. Total Synthesis, Mass Spectrometric Sequencing, and Stabilities of Oligonucleotide Duplexes with Singletrans-anti-BPDE-N6-dA Lesions in theN-rascodon 61 and Other Sequence Contexts Polycyclic Aromatic Compounds. 17: 1-10. DOI: 10.1080/10406639908020596 |
0.623 |
|
| 1999 |
Shafirovich V, Dourandin A, Huang W, Luneva NP, Geacintov NE. Oxidation of Guanine at a Distance in Oligonucleotides Induced by Two-Photon Photoionization of 2-Aminopurine Journal of Physical Chemistry B. 103: 10924-10933. DOI: 10.1021/Jp992002F |
0.551 |
|
| 1998 |
Kochevar IE, Garcia C, Geacintov NE. Photoaddition to DNA by Nonintercalated Chlorpromazine Molecules Photochemistry and Photobiology. 68: 692-697. PMID 9825699 DOI: 10.1111/J.1751-1097.1998.Tb02531.X |
0.474 |
|
| 1998 |
Zou Y, Bassett H, Walker R, Bishop A, Amin S, Geacintov NE, Van Houten B. Hydrophobic forces dominate the thermodynamic characteristics of UvrA-DNA damage interactions. Journal of Molecular Biology. 281: 107-19. PMID 9680479 DOI: 10.1006/Jmbi.1998.1903 |
0.525 |
|
| 1998 |
Fernandes A, Liu T, Amin S, Geacintov NE, Grollman AP, Moriya M. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells. Biochemistry. 37: 10164-72. PMID 9665722 DOI: 10.1021/Bi980401F |
0.419 |
|
| 1998 |
Swenberg CE, Vaishnav YN, Li B, Tsao H, Mao B, Geacintov NE. Single-strand breaks in oligodeoxyribonucleotides induced by fission neutrons and gamma radiation and measured by gel electrophoresis: protective effects of aminothiols. Journal of Radiation Research. 38: 241-54. PMID 9558827 DOI: 10.1269/Jrr.38.241 |
0.473 |
|
| 1998 |
Pirogov N, Shafirovich V, Kolbanovskiy A, Solntsev K, Courtney SA, Amin S, Geacintov NE. Role of hydrophobic effects in the reaction of a polynuclear aromatic diol epoxide with oligodeoxynucleotides in aqueous solutions. Chemical Research in Toxicology. 11: 381-8. PMID 9548810 DOI: 10.1021/Tx980006Q |
0.365 |
|
| 1998 |
Tsao H, Mao B, Zhuang P, Xu R, Amin S, Geacintov NE. Sequence dependence and characteristics of bends induced by site-specific polynuclear aromatic carcinogen-deoxyguanosine lesions in oligonucleotides. Biochemistry. 37: 4993-5000. PMID 9538018 DOI: 10.1021/Bi980291C |
0.686 |
|
| 1998 |
Xu R, Mao B, Amin S, Geacintov NE. Bending and circularization of site-specific and stereoisomeric carcinogen-DNA adducts Biochemistry. 37: 769-778. PMID 9425101 DOI: 10.1021/Bi971785X |
0.592 |
|
| 1998 |
Geacintov NE, Solntsev K, Johnson LW, Chen J, Kolbanovskiy AD, Liu T, Shafirovich VY. Photoinduced electron transfer and strand cleavage in pyrenyl-DNA complexes and adducts Journal of Physical Organic Chemistry. 11: 561-565. DOI: 10.1002/(Sici)1099-1395(199808/09)11:8/9<561::Aid-Poc61>3.0.Co;2-A |
0.432 |
|
| 1997 |
Pilch DS, Yu C, Makhey D, LaVoie EJ, Srinivasan AR, Olson WK, Sauers RR, Breslauer KJ, Geacintov NE, Liu LF. Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs. Biochemistry. 36: 12542-53. PMID 9376359 DOI: 10.1021/Bi971272Q |
0.505 |
|
| 1997 |
Feng B, Gorin A, Kolbanovskiy A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. Biochemistry. 36: 13780-90. PMID 9374854 DOI: 10.1021/Bi970070R |
0.644 |
|
| 1997 |
Feng B, Gorin A, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction. Biochemistry. 36: 13769-79. PMID 9374853 DOI: 10.1021/Bi970069S |
0.679 |
|
| 1997 |
Hess MT, Gunz D, Luneva N, Geacintov NE, Naegeli H. Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes. Molecular and Cellular Biology. 17: 7069-76. PMID 9372938 DOI: 10.1128/Mcb.17.12.7069 |
0.57 |
|
| 1997 |
Shukla R, Jelinsky S, Liu T, Geacintov NE, Loechler EL. How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: Configuration of the adduct bond is more important than those of the hydroxyl groups Biochemistry. 36: 13263-13269. PMID 9341216 DOI: 10.1021/Bi971195Z |
0.385 |
|
| 1997 |
Zhang YJ, Geacintov NE, Santella RM. Development of a monoclonal antibody recognizing benzo[c]phenanthrenediol epoxide-DNA adducts: Application to immunohistochemical detection of DNA damage Chemical Research in Toxicology. 10: 948-952. PMID 9305575 DOI: 10.1021/Tx970050Q |
0.423 |
|
| 1997 |
Shukla R, Liu T, Geacintov NE, Loechler EL. The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G → a) in a 5'-CGT-3' sequence context Biochemistry. 36: 10256-10261. PMID 9254624 DOI: 10.1021/Bi970541+ |
0.377 |
|
| 1997 |
Xu Z, Pilch DS, Srinivasan AR, Olson WK, Geacintov NE, Breslauer KJ. Modulation of nucleic acid structure by ligand binding: induction of a DNA.RNA.DNA hybrid triplex by DAPI intercalation. Bioorganic & Medicinal Chemistry. 5: 1137-47. PMID 9222508 DOI: 10.1016/S0968-0896(97)00050-3 |
0.347 |
|
| 1997 |
Hanrahan CJ, Bacolod MD, Vyas RR, Liu T, Geacintov NE, Loechler EL, Basu AK. Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells. Chemical Research in Toxicology. 10: 369-77. PMID 9114972 DOI: 10.1021/Tx9601925 |
0.482 |
|
| 1997 |
Geacintov NE, Cosman M, Hingerty BE, Amin S, Broyde S, Patel DJ. NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity. Chemical Research in Toxicology. 10: 111-46. PMID 9049424 DOI: 10.1021/Tx9601418 |
0.634 |
|
| 1997 |
Zou Y, Walker R, Bassett H, Geacintov NE, Van Houten B. Formation of DNA repair intermediates and incision by the ATP-dependent UvrB-UvrC endonuclease. The Journal of Biological Chemistry. 272: 4820-7. PMID 9030538 DOI: 10.1074/Jbc.272.8.4820 |
0.522 |
|
| 1997 |
Shafirovich VY, Dourandin A, Luneva NP, Geacintov NE. Migration and trapping of photoinjected excess electrons in double-stranded B-form DNA but not in single-stranded DNA Journal of Physical Chemistry B. 101: 5863-5868. DOI: 10.1021/Jp970308L |
0.494 |
|
| 1996 |
Moriya M, Spiegel S, Fernandes A, Amin S, Liu T, Geacintov N, Grollman AP. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality. Biochemistry. 35: 16646-51. PMID 8988000 DOI: 10.1021/Bi9608875 |
0.47 |
|
| 1996 |
Choi DJ, Roth RB, Liu T, Geacintov NE, Scicchitano DA. Incorrect base insertion and prematurely terminated transcripts during T7 RNA polymerase transcription elongation past benzo[a]pyrenediol epoxide-modified DNA Journal of Molecular Biology. 264: 213-219. PMID 8951371 DOI: 10.1006/Jmbi.1996.0635 |
0.491 |
|
| 1996 |
Liu T, Xu J, Tsao H, Li B, Xu R, Yang C, Amin S, Moriya M, Geacintov NE. Base sequence-dependent bends in site-specific benzo[a]pyrene diol epoxide-modified oligonucleotide duplexes. Chemical Research in Toxicology. 9: 255-61. PMID 8924600 DOI: 10.1021/Tx9501086 |
0.455 |
|
| 1996 |
Xu R, Dwarakanath S, Cosman M, Amin S, Geacintov NE. Site-specific adducts derived from the binding of anti-5-methylchrysene diol epoxide enantiomers to DNA: Synthesis and characteristics Carcinogenesis. 17: 2035-2042. PMID 8824532 DOI: 10.1093/Carcin/17.9.2035 |
0.462 |
|
| 1996 |
Cosman M, Hingerty BE, Luneva N, Amin S, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove. Biochemistry. 35: 9850-63. PMID 8703959 DOI: 10.1021/Bi9605346 |
0.649 |
|
| 1996 |
MacLeod MC, Powell KL, Kuzmin VA, Kolbanovskiy A, Geacintov NE. Interference of benzo[a]pyrene diol epoxide-deoxyguanosine adducts in a GC box with binding of the transcription factor Sp1. Molecular Carcinogenesis. 16: 44-52. PMID 8634093 DOI: 10.1002/(Sici)1098-2744(199605)16:1<44::Aid-Mc6>3.0.Co;2-O |
0.404 |
|
| 1996 |
Cosman M, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. NMR Solution Structures of Adducts Derived from the Binding of Polycyclic Aromatic Diol Epoxides to DNA Polycyclic Aromatic Compounds. 10: 153-160. DOI: 10.1080/10406639608034692 |
0.633 |
|
| 1996 |
Amin S, Laryea A, Cosman M, Liu T, Xu R, Dwarakanath S, Mao B, Smirnov S, Harvey RG, Hecht SS, Geacintov NE. Direct Synthesis and Characterization of Site-Specific Deoxyguanosyl and Deoxyadenosyl Adducts Derived from the Binding of Pah Diol Epoxides to Oligonucleotides Polycyclic Aromatic Compounds. 10: 137-144. DOI: 10.1080/10406639608034690 |
0.377 |
|
| 1996 |
Marky LA, Rentzeperis D, Luneva NP, Cosman M, Geacintov NE, Kupke DW. Differential hydration thermodynamics of stereoisomeric DNA-benzo[a]pyrene adducts derived from diol epoxide enantiomers with different tumorigenic potentials Journal of the American Chemical Society. 118: 3804-3810. DOI: 10.1021/Ja9538703 |
0.515 |
|
| 1995 |
Mao B, Xu J, Li B, Margulis LA, Smirnov S, Ya NQ, Courtney SH, Geacintov NE. Synthesis and characterization of covalent adducts derived from the binding of benzo[a]pyrene diol expoxide to a -GGG- sequence in a deoxyoligonucleotide. Carcinogenesis. 16: 357-65. PMID 7859369 DOI: 10.1093/Carcin/16.2.357 |
0.485 |
|
| 1995 |
Cosman M, Laryea A, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer. Biochemistry. 34: 1295-307. PMID 7827077 DOI: 10.1021/Bi00004A024 |
0.652 |
|
| 1995 |
Cosman M, Xu R, Hingerty BE, Amin S, Harvey RG, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site. Biochemistry. 34: 6247-60. PMID 7742330 DOI: 10.1021/Bi00018A029 |
0.683 |
|
| 1995 |
Xu R, Mao B, Xu J, Li B, Birke S, Swenberg CE, Geacintov NE. Stereochemistry-dependent bending in oligonucleotide duplexes induced by site-specific covalent benzo[a]pyrene diol epoxide-guanine lesions. Nucleic Acids Research. 23: 2314-9. PMID 7610061 DOI: 10.1093/Nar/23.12.2314 |
0.45 |
|
| 1995 |
Laryea A, Cosman M, Lin JM, Liu T, Agarwal R, Smirnov S, Amin S, Harvey RG, Dipple A, Geacintov NE. Direct synthesis and characterization of site-specific adenosyl adducts derived from the binding of a 3,4-dihydroxy-1,2-epoxybenzo[c]phenanthrene stereoisomer to an 11-mer oligodeoxyribonucleotide. Chemical Research in Toxicology. 8: 444-54. PMID 7578932 DOI: 10.1021/Tx00045A017 |
0.386 |
|
| 1995 |
Li B, Mao B, Liu TM, Xu J, Dourandin A, Amin S, Geacintov NE. Laser pulse-induced photochemical strand cleavage of site-specifically and covalently modified (+)-anti-benzo[a]pyrene diol epoxide-oligonucleotide adducts. Chemical Research in Toxicology. 8: 396-402. PMID 7578926 DOI: 10.1021/Tx00045A011 |
0.442 |
|
| 1995 |
Suh M, Ariese F, Small GJ, Jankowiak R, Liu TM, Geacintov NE. Conformational studies of the (+)-trans, (-)-trans, (+)-cis, and (-)-cis adducts of anti-benzo[a]pyrene diolepoxide to N2-dG in duplex oligonucleotides using polyacrylamide gel electrophoresis and low-temperature fluorescence spectroscopy. Biophysical Chemistry. 56: 281-96. PMID 7578905 DOI: 10.1016/0301-4622(95)00055-3 |
0.425 |
|
| 1995 |
Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction. Biochemistry. 34: 15334-50. PMID 7578150 DOI: 10.1021/Bi00046A043 |
0.684 |
|
| 1995 |
Jelinsky SA, Liu T, Geacintov NE, Loechler EL. The major, N2-gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G→A and G→C, in addition to G→T, mutations Biochemistry. 34: 13545-13553. PMID 7577943 DOI: 10.1021/Bi00041A034 |
0.355 |
|
| 1995 |
Hsu TM, Liu TM, Amin S, Geacintov NE, Santella RM. Determination of stereospecificity of benzo[a]pyrene diolepoxide-dna antisera with site-specifically modified oligonucleotides Carcinogenesis. 16: 2263-2265. PMID 7554088 DOI: 10.1093/Carcin/16.9.2263 |
0.456 |
|
| 1995 |
Zou Y, Liu TM, Geacintov NE, Van Houten B. Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)- Or dG-(-)-anti-BPDE Biochemistry. 34: 13582-13593. DOI: 10.1021/Bi00041A038 |
0.517 |
|
| 1994 |
Balasta L, Xu R, Geacintov NE, Swenberg CE, Amin S, Hecht SS. Unwinding and hydrodynamic flow linear dichroism characteristics of supercoiled DNA covalently modified with two isomeric methylchrysene diol epoxides of different biological activities. Chemical Research in Toxicology. 6: 616-24. PMID 8292738 DOI: 10.1021/Tx00035A005 |
0.516 |
|
| 1994 |
Choi DJ, Marino-Alessandri DJ, Geacintov NE, Scicchitano DA. Site-specific benzo[a]pyrene diol epoxide-DNA adducts inhibit transcription elongation by bacteriophage T7 RNA polymerase Biochemistry. 33: 780-787. PMID 8292606 DOI: 10.1021/Bi00169A020 |
0.513 |
|
| 1994 |
MacLeod MC, Evans FE, Lay J, Chiarelli P, Geacintov NE, Powell KL, Daylong A, Luna E, Harvey RG. Identification of a novel, N7-deoxyguanosine adduct as the major DNA adduct formed by a non-bay-region diol epoxide of benzo[a]pyrene with low mutagenic potential. Biochemistry. 33: 2977-87. PMID 8130212 |
0.444 |
|
| 1994 |
Suh M, Jankowiak R, Ariese F, Mao B, Geacintov NE, Small GJ. Flanking base effects on the structural conformation of the (+)-trans-anti-benzo[a]pyrene diolepoxide adduct to N2-dG in sequence-defined oligonucleotides. Carcinogenesis. 15: 2891-8. PMID 8001252 DOI: 10.1093/Carcin/15.12.2891 |
0.483 |
|
| 1994 |
Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. Biochemistry. 33: 11518-27. PMID 7918365 DOI: 10.1021/bi00204a014 |
0.648 |
|
| 1994 |
Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove. Biochemistry. 33: 11507-17. PMID 7918364 DOI: 10.1021/bi00204a013 |
0.609 |
|
| 1994 |
Shafirovich VY, Levin PP, Kuzmin VA, Thorgeirsson TE, Kliger DS, Geacintov NE. Photoinduced electron transfer and enhanced triplet yields in benzo[a]pyrene derivative-nucleic acid complexes and covalent adducts Journal of the American Chemical Society. 116: 63-72. DOI: 10.1021/Ja00080A008 |
0.44 |
|
| 1994 |
O'Connor D, Shafirovich VY, Geacintov NE. Influence of adduct stereochemistry and hydrogen-bonding solvents on photoinduced charge transfer in a covalent benzo[a]pyrene diol epoxide-nucleoside adduct on picosecond time scales Journal of Physical Chemistry. 98: 9831-9839. DOI: 10.1021/J100090A017 |
0.305 |
|
| 1993 |
Chen J, MacLeod MC, Zhao R, Geacintov NE. Fluorescence HPLC methods for detecting benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide-deoxyadenosine adducts in enzyme-digests of modified DNA: improved sensitivity. Carcinogenesis. 14: 1049-51. PMID 8504464 DOI: 10.1093/Carcin/14.5.1049 |
0.367 |
|
| 1993 |
Cosman M, de los Santos C, Fiala R, Hingerty BE, Ibanez V, Luna E, Harvey R, Geacintov NE, Broyde S, Patel DJ. Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine. Biochemistry. 32: 4145-55. PMID 8476845 DOI: 10.1021/Bi00067A001 |
0.638 |
|
| 1993 |
Margulis LA, Ibanez V, Geacintov NE. Base-sequence dependence of covalent binding of benzo[a]pyrene diol epoxide to guanine in oligodeoxyribonucleotides Chemical Research in Toxicology. 6: 59-63. PMID 8448351 DOI: 10.1021/Tx00031A009 |
0.407 |
|
| 1993 |
Geacintov NE, Zhao R, Kuzmin VA, Kim SK, Pecora LJ. Mechanisms of quenching of the fluorescence of a benzo[a]pyrene tetraol metabolite model compound by 2'-deoxynucleosides. Photochemistry and Photobiology. 58: 185-94. PMID 8415908 DOI: 10.1111/J.1751-1097.1993.Tb09547.X |
0.348 |
|
| 1993 |
Cosman M, Fiala R, Hingerty BE, Laryea A, Lee H, Harvey RG, Amin S, Geacintov NE, Broyde S, Patel D. Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair. Biochemistry. 32: 12488-97. PMID 8241140 DOI: 10.1021/Bi00097A029 |
0.68 |
|
| 1993 |
Geacintov NE. Opposite stereoselective resistance to digestion by phosphodiesterases I and II of benzo[a]pyrene diol epoxide-modified oligonucleotide adducts Biochemistry®. 32: 11785-11793. PMID 8218249 DOI: 10.1021/Bi00095A006 |
0.415 |
|
| 1993 |
Mao B, Margulis LA, Li B, Ibanez V, Lee H, Harvey RG, Geacintov NE. Direct synthesis and identification of benzo[a]pyrene diol epoxide-deoxyguanosine binding sites in modified oligodeoxynucleotides. Chemical Research in Toxicology. 5: 773-8. PMID 1489927 DOI: 10.1021/Tx00030A007 |
0.414 |
|
| 1992 |
de los Santos C, Cosman M, Hingerty BE, Ibanez V, Margulis LA, Geacintov NE, Broyde S, Patel DJ. Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer. Biochemistry. 31: 5245-52. PMID 1606148 DOI: 10.1021/Bi00138A002 |
0.619 |
|
| 1992 |
Xu R, Birke S, Carberry SE, Geacintov NE, Swenberg CE, Harvey RG. Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide. Nucleic Acids Research. 20: 6167-76. PMID 1475180 DOI: 10.1093/Nar/20.23.6167 |
0.524 |
|
| 1992 |
Zhao R, Liu TM, Kim SK, MacLeod MC, Geacintov NE. Identification and quantitative detection of isomeric benzo[a]pyrene diolepoxide--DNA adducts by low-temperature conventional fluorescence methods. Carcinogenesis. 13: 1817-24. PMID 1423840 DOI: 10.1093/Carcin/13.10.1817 |
0.449 |
|
| 1992 |
Cosman M, de los Santos C, Fiala R, Hingerty BE, Singh SB, Ibanez V, Margulis LA, Live D, Geacintov NE, Broyde S. Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA. Proceedings of the National Academy of Sciences of the United States of America. 89: 1914-8. PMID 1311854 DOI: 10.1073/Pnas.89.5.1914 |
0.629 |
|
| 1991 |
Swenberg CE, Birke S, Geacintov NE. Characterization of the interaction of the radioprotector 1-methyl-2-[2-(methylthio)-2-piperidinovinyl]quinolinium iodide with supercoiled DNA Radiation Research. 127: 138-145. PMID 1946996 DOI: 10.2307/3577957 |
0.488 |
|
| 1991 |
Geacintov NE, Cosman M, Mao B, Alfano A, Ibanez V, Harvey RG. Spectroscopic characteristics and site I/site II classification of cis and trans benzo[a]pyrene diolepoxide enantiomer-guanosine adducts in oligonucleotides and polynucleotides. Carcinogenesis. 12: 2099-108. PMID 1934295 DOI: 10.1093/Carcin/12.11.2099 |
0.404 |
|
| 1991 |
Roche CJ, Jeffrey AM, Mao B, Alfano A, Kim SK, Ibanez V, Geacintov NE. Dependence of conformations of benzo[a]pyrene diol epoxide-DNA adducts derived from stereoisomers of different tumorigenicities on base sequence. Chemical Research in Toxicology. 4: 311-7. PMID 1912314 DOI: 10.1021/Tx00021A009 |
0.412 |
|
| 1991 |
Singh SB, Hingerty BE, Singh UC, Greenberg JP, Geacintov NE, Broyde S. Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer. Cancer Research. 51: 3482-92. PMID 1905197 |
0.6 |
|
| 1991 |
Geacintov NE, Swenberg CE. Chemical, molecular biology, and genetic techniques for correlating DNA base damage induced by ionizing radiation with biological end points Basic Life Sciences. 58: 453-473; discussion . PMID 1811481 DOI: 10.1007/978-1-4684-7627-9_17 |
0.497 |
|
| 1990 |
Kim MH, Roche CJ, Geacintov NE, Pope M, Pataki J, Harvey RG. Conformations of complexes derived from the interactions of two stereoisomeric bay-region 5-methylchrysene diol epoxides with DNA. Journal of Biomolecular Structure & Dynamics. 3: 949-65. PMID 3271420 DOI: 10.1080/07391102.1986.10508476 |
0.473 |
|
| 1990 |
Geacintov NE, Lee MS, Ibanez V, Amin S, Hecht SS. Differences in conformations of covalent adducts derived from the binding of 5- and 6-methylchrysene diol epoxide stereoisomers to DNA. Carcinogenesis. 11: 985-9. PMID 2347073 DOI: 10.1093/Carcin/11.6.985 |
0.441 |
|
| 1990 |
Swenberg CE, Carberry SE, Geacintov NE. Linear dichroism characteristics of ethidium- and proflavine-supercoiled DNA complexes Biopolymers. 29: 1735-1744. PMID 2145043 DOI: 10.1002/Bip.360291406 |
0.471 |
|
| 1990 |
Jankowiak R, Lu PQ, Small GJ, Geacintov NE. Laser spectroscopic studies of DNA adduct structure types from enantiomeric diol epoxides of benzo[a]pyrene Chemical Research in Toxicology. 3: 39-46. PMID 2131823 DOI: 10.1021/Tx00013A007 |
0.449 |
|
| 1990 |
Jankowiak R, Lu P, Small GJ, Nishimoto M, Varanasi U, Kim SK, Geacintov NE. Fluorescence line-narrowing spectrometry: a versatile tool for the study of chemically initiated carcinogenesis. Journal of Pharmaceutical and Biomedical Analysis. 8: 113-21. PMID 2128812 DOI: 10.1016/0731-7085(90)80017-J |
0.511 |
|
| 1990 |
Cosman M, Ibanez V, Geacintov NE, Harvey RG. Preparation and isolation of adducts in high yield derived from the binding of two benzo[a]pyrene-7,8-dihydroxy-9,10-oxide stereoisomers to the oligonucleotide d(atatgtata) Carcinogenesis. 11: 1667-1672. PMID 2119261 DOI: 10.1093/Carcin/11.9.1667 |
0.365 |
|
| 1989 |
Carberry SE, Geacintov NE, Harvey RG. Reactions of stereoisomeric non-bay-region benz[a]anthracene diol epoxides with DNA and conformations of non-covalent complexes and covalent adducts Carcinogenesis. 10: 97-103. PMID 2910537 DOI: 10.1093/Carcin/10.1.97 |
0.503 |
|
| 1989 |
Slama-Schwok A, Rougée M, Ibanez V, Geacintov NE, Montenay-Garestier T, Lehn JM, Hélène C. Interactions of the dimethyldiazaperopyrenium dication with nucleic acids. 2. Binding to double-stranded polynucleotides. Biochemistry. 28: 3234-42. PMID 2742836 DOI: 10.1021/Bi00434A018 |
0.436 |
|
| 1989 |
van Houte LP, van Grondelle R, Retèl J, Westra JG, Zinger D, Sutherland JC, Kim SK, Geacintov NE. Excited state properties of the N-(deoxyguanosin-8-yl)-2-aminofluorene adducts. Photochemistry and Photobiology. 49: 387-94. PMID 2727079 DOI: 10.1111/J.1751-1097.1989.Tb09184.X |
0.305 |
|
| 1989 |
Kim SK, Geacintov NE, Zinger D, Sutherland JC. Fluorescence spectral characteristics and fluorescence decay profiles of covalent polycyclic aromatic carcinogen-DNA adducts Basic Life Sciences. 51: 187-205. PMID 2510712 DOI: 10.1007/978-1-4684-8041-2_21 |
0.347 |
|
| 1989 |
Roche CJ, Geacintov NE, Ibanez V, Harvey RG. Linear dichroism properties and orientations of different ultraviolet transition moments of benzo[a]pyrene derivatives bound noncovalently and cova Biophysical Chemistry. 33: 277-288. PMID 2508781 DOI: 10.1016/0301-4622(89)80029-8 |
0.513 |
|
| 1989 |
Kim SK, Brenner HC, Soh BJ, Geacintov NE. Fluorescence spectroscopy of benzo[a]pyrene diol epoxide-DNA adducts. Conformation-specific emission spectra. Photochemistry and Photobiology. 50: 327-337. PMID 2506585 DOI: 10.1111/J.1751-1097.1989.Tb04166.X |
0.447 |
|
| 1989 |
Kim SK, Geacintov NE, Brenner HC, Harvey RG. Identification of conformationally different binding sites in benzo[a]pyrene diol epoxide - DNA adducts by low-temperature fluorescence spectroscopy Carcinogenesis. 10: 1333-1335. PMID 2500269 DOI: 10.1093/Carcin/10.7.1333 |
0.487 |
|
| 1988 |
Carberry SE, Shahbaz M, Geacintov NE, Harvey RG. Reactions of stereoisomeric and structurally related bay region diol epoxide derivatives of benz[a]anthracene with DNA. Conformations of non-covalent complexes and covalent carcinogen-DNA adducts Chemico-Biological Interactions. 66: 121-145. PMID 3383284 DOI: 10.1016/0009-2797(88)90046-4 |
0.505 |
|
| 1988 |
Zinger D, Geacintov NE. Acrylamide and molecular oxygen fluorescence quenching as a probe of solvent-accessibility of aromatic fluorophores complexed with DNA in relation to their conformations: coronene-DNA and other complexes Photochemistry and Photobiology. 47: 181-188. PMID 3344287 DOI: 10.1111/J.1751-1097.1988.Tb02711.X |
0.481 |
|
| 1988 |
Geacintov NE, Shahbaz M, Ibanez V, Moussaoui K, Harvey RG. Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides Biochemistry. 27: 8380-8387. PMID 3149504 DOI: 10.1021/Bi00422A013 |
0.32 |
|
| 1988 |
Geacintov NE. Applications of Fluorescence Techniques in the Analysis of Polycyclic Aromatic Carcinogen—DNA Adduct Astm Special Technical Publications. 54-66. DOI: 10.1520/Stp19690S |
0.376 |
|
| 1987 |
Geacintov NE. Orientation and linear dichroism characteristics of porphyrin-DNA complexes Biochemistry. 26: 3087-3092. PMID 3607012 DOI: 10.1021/Bi00385A021 |
0.506 |
|
| 1987 |
Vigny P, Blais J, Ibanez V, Geacintov NE. A flow linear dichroism study of the orientation of 4',5'-psoralen-DNA photoadducts Photochemistry and Photobiology. 45: 601-607. PMID 3602111 DOI: 10.1111/J.1751-1097.1987.Tb07386.X |
0.492 |
|
| 1987 |
Zinger D, Geacintov NE, Harvey RG. Conformations and selective photodissociation of heterogeneous benzo(a)pyrene diol epoxide enantiomer-DNA adducts Biophysical Chemistry. 27: 131-138. PMID 3117127 DOI: 10.1016/0301-4622(87)80053-4 |
0.488 |
|
| 1987 |
Kolubayev V, Brenner HC, Geacintov NE. Stereoselective covalent binding of enantiomers of anti-benzo[a]pyrene diol epoxide to DNA as probed by optical detection of magnetic resonance Biochemistry. 26: 2638-2641. PMID 3111532 DOI: 10.1021/Bi00383A035 |
0.396 |
|
| 1987 |
Geacintov NE, Zinger D, Ibanez V, Santella R, Grunberger D, Harvey RG. Properties of covalent benzo[a]pyrene diol epoxide-DNA adducts investigated by fluorescence techniques. Carcinogenesis. 8: 925-35. PMID 3109756 DOI: 10.1093/Carcin/8.7.925 |
0.44 |
|
| 1987 |
Yoshida H, Swenberg CE, Geacintov NE. Kinetic flow dichroism study of conformational changes in supercoiled DNA induced by ethidium bromide and noncovalent and covalent binding of benzo[a]pyrene diol epoxide Biochemistry. 26: 1351-1358. PMID 2952167 DOI: 10.1021/Bi00379A022 |
0.505 |
|
| 1986 |
Kim MH, Geacintov NE, Mcquillen DG, Pope M, Harvey RG. Reaction mechanisms of trans-9,10-dihydroxy-anti-7,8-epoxy-7,8,9,10-tetrahydro-3-methylcholanthrene with DNA in aqueous solutions. conformation of adducts Carcinogenesis. 7: 41-47. PMID 3943143 DOI: 10.1093/Carcin/7.1.41 |
0.491 |
|
| 1986 |
Geacintov NE. Is intercalation a critical factor in the covalent binding of mutagenic and tumorigenic polycyclic aromatic diol epoxides to dna? Carcinogenesis. 7: 759-766. PMID 3698204 DOI: 10.1093/Carcin/7.5.759 |
0.477 |
|
| 1986 |
Shahbaz M, Geacintov NE, Harvey RG. Noncovalent intercalative complex formation and kinetic flow linear dichroism of racemic syn- and anti-benzo[a]pyrenediol epoxide-DNA solutions Biochemistry. 25: 3290-3296. PMID 3089275 DOI: 10.1021/Bi00359A031 |
0.442 |
|
| 1985 |
Kim MH, Geacintov NE, Pope M, Pataki J, Harvey RG. Reaction mechanisms of trans-1,2-dihydroxy-anti-3,4-epoxy-1,2,3,4-tetrahydro-5-methylchrysene with DNA in aqueous solutions. Carcinogenesis. 6: 121-6. PMID 3967331 DOI: 10.1093/Carcin/6.1.121 |
0.401 |
|
| 1985 |
Moussaoui K, Geacintov NE, Harvey RG. Reactivity and binding of benzo(a)pyrene diol epoxide to poly(dG-dC)·(dG-dC) and poly(dG-m5dC)·(dg-m5dC) in the B and Z forms Biophysical Chemistry. 22: 285-297. PMID 3933587 DOI: 10.1016/0301-4622(85)80052-1 |
0.302 |
|
| 1984 |
Geacintov NE, Ibanez V, Gagliano AG, Jacobs SA, Harvey RG. Stereoselective covalent binding of anti-benzo(a)pyrene diol epoxide to DNA conformation of enantiomer adducts. Journal of Biomolecular Structure & Dynamics. 1: 1473-84. PMID 6443875 DOI: 10.1080/07391102.1984.10507531 |
0.474 |
|
| 1984 |
Kim MH, Geacintov NE, Pope M, Harvey RG. Structural effects in reactivity and adduct formation of polycyclic aromatic epoxide and diol epoxide derivatives with DNA: Comparison between 1-oxiranylpyrene and benzo[a]pyrenediol epoxide Biochemistry. 23: 5433-5439. PMID 6439240 DOI: 10.1021/Bi00318A009 |
0.515 |
|
| 1984 |
Geacintov NE, Hibshoosh H, Ibanez V, Benjamin MJ, Harvey RG. Mechanisms of reaction of benzo(a)pyrene-7,8-diol-9,10-epoxide with DNA in aqueous solutions Biophysical Chemistry. 20: 121-133. PMID 6435696 DOI: 10.1016/0301-4622(84)80012-5 |
0.442 |
|
| 1984 |
Geacintov NE, Yoshida H, Ibanez V, Jacobs SA, Harvey RG. Conformations of adducts and kinetics of binding to DNA of the optically pure enantiomers of anti-benzo(a)pyrene diol epoxide. Biochemical and Biophysical Research Communications. 122: 33-9. PMID 6430294 DOI: 10.1016/0006-291X(84)90435-2 |
0.431 |
|
| 1983 |
Gagliano AG, Geacintov NE, Ibanez V, Harvey RG, Lee HM. Application of fluorescence and linear dichroism techniques to the characterization of the covalent adducts derived from interaction of (+/-)-trans-9,10-dihydroxy-anti-11,12-epoxy-9,10,11,12-tetrahydro-benzo[e]pyrene with DNA. Carcinogenesis. 3: 969-76. PMID 7139871 DOI: 10.1093/Carcin/3.9.969 |
0.437 |
|
| 1983 |
Geacintov NE, Gagliano AG, Ibanez V, Lee H, Jacobs SA, Harvey RG. Linear dichroism studies of conformations of carcinogen-DNA adducts application to covalent complexes derived from the reactions of the two enantiomers of 9,10-epoxy-9,10,11,12-tetrahydrobenzo(e)pyrene with DNA. Journal of Biomolecular Structure & Dynamics. 1: 913-23. PMID 6443881 DOI: 10.1080/07391102.1983.10507493 |
0.435 |
|
| 1982 |
Geacintov NE, Gagliano AG, Ibanez V, Harvey RG. Spectroscopic characterizations and comparisons of the structures of the covalent adducts derived from the reactions of 7,8-dihydroxy-7,8,9,10-tetrahydrobenzo [a]pyrene-9,10-oxide, and the 9,10-epoxides of 7,8,9,10-tetrahydrobenzo[a]pyrene and 9,10,11,12-tetrahydrobenzo[e]pyrene with DNA Carcinogenesis. 3: 247-253. PMID 7083468 DOI: 10.1093/Carcin/3.3.247 |
0.484 |
|
| 1982 |
Poulos AT, Kuzmin V, Geacintov NE. Probing the microenvironmental of benzo[a]pyrene diol epoxide-DNA adducts by triplet excited state quenching methods Journal of Biochemical and Biophysical Methods. 6: 269-281. PMID 6815256 DOI: 10.1016/0165-022X(82)90009-4 |
0.501 |
|
| 1982 |
Geacintov NE, Yoshida H, Ibanez V, Harvey RG. Noncovalent binding of 7β,8α-dihydroxy-9α, 10α-epoxytetrahydrobenzo[a]pyrene to deoxyribonucleic acid and its catalytic effect on the hydrolysis of the diol epoxide to tetrol Biochemistry. 21: 1864-1869. PMID 6805508 DOI: 10.1021/Bi00537A025 |
0.483 |
|
| 1982 |
Geacintov NE, Hibshoosh H, Ibanez V. Mechanisms of covalent binding of benzo(a)pyrene diol epoxide to DNA Proceedings of the American Association For Cancer Research. |
0.349 |
|
| 1981 |
Geacintov NE, Yoshida H, Ibanez V, Harvey RG. Non-covalent intercalative binding of 7,8-dihydroxy-9,10-epoxybenzo(a)pyrene to DNA Biochemical and Biophysical Research Communications. 100: 1569-1577. PMID 6794569 DOI: 10.1016/0006-291X(81)90698-7 |
0.392 |
|
| 1981 |
Geacintov NE, Waldmeyer J, Kuzmin VA, Kolubayev T. Dynamics of the binding of acridine dyes to DNA investigated by triplet excited state probe techniques Journal of Physical Chemistry. 85: 3608-3613. DOI: 10.1021/J150624A018 |
0.462 |
|
| 1981 |
Geacintov NE, Ibanez V, Yoshida H. Mechanisms of interaction of benzo(a)pyrene diol epoxide and related compounds with DNA conformation of adducts Journal of Supramolecular and Cellular Biochemistry. 15. |
0.329 |
|
| 1980 |
Geacintov NE, Ibanez V, Gagliano AG, Yoshida H, Harvey RG. Kinetics of hydrolysis to tetraols and binding of benzo(a)pyrene-7,8-dihydrodiol-9, 10-oxide and its tetraol derivatives to DNA. Conformation of adducts. Biochemical and Biophysical Research Communications. 92: 1335-42. PMID 6768360 DOI: 10.1016/0006-291X(80)90432-5 |
0.497 |
|
| 1980 |
Ibanez V, Geacintov NE, Gagliano AG, Brandimarte S, Harvey RG. Physical binding of tetraols derived from 7,8-dihydroxy-9,10-epoxybenzo[a]pyrene to DNA Journal of the American Chemical Society. 102: 5661-5666. DOI: 10.1021/Ja00537A043 |
0.431 |
|
| 1980 |
IBANEZ V, GEACINTOV NE, GAGLIANO AG, BRANDIMARTE S, HARVEY RG. ChemInform Abstract: PHYSICAL BINDING OF TETRAOLS DERIVED FROM 7,8-DIHYDROXY-9,10-EPOXYBENZO(A)PYRENE TO DNA Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198046098 |
0.321 |
|
| 1979 |
Prusik T, Geacintov NE. Fluorescence properties of a benzo(a)pyrene 7,8 dihydrodiol 9,10-oxide-DNA adduct. Conformation and effects of intermolecular DNA interactions Biochemical and Biophysical Research Communications. 88: 782-790. PMID 572681 DOI: 10.1016/0006-291X(79)91476-1 |
0.514 |
|
| 1979 |
Prusik T, Geacintov NE, Tobiasz C, Ivanovic V, Weinstein IB. Fluorescence study of the physico-chemical properties of a benzo(a)pyrene 7,8-dihydrodiol 9,10-oxide derivative bound covalently to DNA Photochemistry and Photobiology. 29: 223-232. PMID 482375 DOI: 10.1111/J.1751-1097.1979.Tb07043.X |
0.512 |
|
| 1978 |
Ivanovic V, Geacintov NE, Yamasaki H, Weinstein IB. DNA and RNA adducts formed in hamster embryo cell cultures exposed to benzo[a]pyrene Biochemistry. 17: 1597-1603. PMID 656393 DOI: 10.1021/Bi00602A003 |
0.461 |
|
| 1978 |
Geacintov NE. Electric linear dichroism study on the orientation of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide covalently bound to DNA Biochemistry. 17: 5256-5262. PMID 569497 DOI: 10.1021/Bi00617A027 |
0.493 |
|
| 1978 |
Ivanovic V, Geacintov NE, Jeffrey AM, Fu PP, Harvey RG, Weinstein IB. Cell and microsome mediated binding of 7,12-dimethylbenz(a)anthracene to DNA studied by fluorescence spectroscopy. Cancer Letters. 4: 131-40. PMID 417802 DOI: 10.1016/S0304-3835(78)93962-9 |
0.513 |
|
| 1978 |
Geacintov NE, Prusik T. Spectroscopic studies of carcinogen-DNA complexes. Structure of the covalent benzo(a)pyrene 7,8-dihydrodiol 9,10-oxide-DNA adduct Proceedings of the American Association For Cancer Research. |
0.395 |
|
| 1978 |
Ivanovic V, Geacintov NE, Prusik T. Spectroscopic techniques for investigation of carcinogen-DNA complexes. Conformation of the covalent benzo(a)pyrene (BP) 7,8-dihydrodiol 9,10-oxide-DNA adduct Federation Proceedings. 37. |
0.395 |
|
| 1976 |
Prusik T, Geacintov NE. Triplets of aromatic dyes bound to DNA as probes of the mobility of DNA-bound metal ions Febs Letters. 71: 236-240. PMID 1001442 DOI: 10.1016/0014-5793(76)80940-4 |
0.402 |
|
| 1976 |
Geacintov NE, Prusik T, Khosrofian JM. Properties of benzopyrene-DNA complexes investigated by fluorescence and triplet flash photolysis techniques Journal of the American Chemical Society. 98: 6444-6452. PMID 972216 DOI: 10.1021/Ja00437A002 |
0.422 |
|
| 1976 |
Ivanovic V, Geacintov NE, Weinstein IB. Cellular binding of benzo(a)pyrene to DNA characterized by low temperature fluorescence Biochemical and Biophysical Research Communications. 70: 1172-1179. PMID 942439 DOI: 10.1016/0006-291X(76)91026-3 |
0.45 |
|
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