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Keith L. Keene, Ph.D. - Publications

Affiliations: 
2007 Wake Forest University, Winston-Salem, NC, United States 
Area:
Genetics
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Aldridge CM, Braun R, Keene KL, Hsu FC, Worrall BB. Single Nucleotide Polymorphisms Associated With Motor Recovery in Patients With Nondisabling Stroke: GWAS Study. Neurology. PMID 37813584 DOI: 10.1212/WNL.0000000000207716  0.311
2020 Keene KL, Hyacinth HI, Bis JC, Kittner SJ, Mitchell BD, Cheng YC, Pare G, Chong M, O'Donnell M, Meschia JF, Chen WM, Sale MM, Rich SS, Nalls MA, Zonderman AB, et al. Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. Stroke. STROKEAHA120029123. PMID 32693751 DOI: 10.1161/Strokeaha.120.029123  0.351
2019 Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, ... ... Keene KL, et al. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics. PMID 31160810 DOI: 10.1038/S41588-019-0449-0  0.369
2018 Green IE, Rahman SA, Owens DL, Sale MM, Currie LJ, Keene KL, Worrall BB, Southerland AM. Cervical Artery Dissection in Patients of African Ancestry. Cerebrovascular Diseases (Basel, Switzerland). 46: 218-222. PMID 30517918 DOI: 10.1159/000494704  0.447
2018 Davis Armstrong NM, Chen WM, Brewer MS, Williams SR, Sale MM, Worrall BB, Keene KL. Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial. Frontiers in Genetics. 9: 358. PMID 30237808 DOI: 10.3389/Fgene.2018.00358  0.34
2017 Williams SR, Hsu FC, Keene KL, Chen WM, Dzhivhuho G, Rowles JL, Southerland AM, Furie KL, Rich SS, Worrall BB, Sale MM. Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke. Stroke. PMID 28495826 DOI: 10.1161/Strokeaha.116.015677  0.321
2017 Fernández-Cadenas I, Mendióroz M, Giralt D, Nafria C, Garcia E, Carrera C, Gallego-Fabrega C, Domingues-Montanari S, Delgado P, Ribó M, Castellanos M, Martínez S, Freijo M, Jiménez-Conde J, Rubiera M, ... ... Keene K, et al. GRECOS Project (Genotyping Recurrence Risk of Stroke): The Use of Genetics to Predict the Vascular Recurrence After Stroke. Stroke. PMID 28411264 DOI: 10.1161/Strokeaha.116.014322  0.306
2016 Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, ... ... Keene KL, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications. 7: 10023. PMID 26831199 DOI: 10.1038/Ncomms10023  0.363
2016 Williams SR, Hsu FC, Keene KL, Chen WM, Nelson S, Southerland AM, Madden EB, Coull B, Gogarten SM, Furie KL, Dzhivhuho G, Rowles JL, Mehndiratta P, Malik R, Dupuis J, et al. Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke. Neurology. 86: 351-9. PMID 26718567 DOI: 10.1212/Wnl.0000000000002319  0.309
2015 Carty CL, Keene KL, Cheng YC, Meschia JF, Chen WM, Nalls M, Bis JC, Kittner SJ, Rich SS, Tajuddin S, Zonderman AB, Evans MK, Langefeld CD, Gottesman R, Mosley TH, et al. Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. Stroke; a Journal of Cerebral Circulation. PMID 26089329 DOI: 10.1161/Strokeaha.115.009044  0.389
2014 Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ, Yanek LR, Nalls MA, Comeau ME, Rasmussen-Torvik LJ, Jensen RA, Evans DS, Sun YV, ... ... Keene KL, et al. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. Plos Genetics. 10: e1004517. PMID 25102180 DOI: 10.1371/Journal.Pgen.1004517  0.617
2014 Tomlinson MJ, Pitsillides A, Pickin R, Mika M, Keene KL, Hou X, Mychaleckyj J, Chen WM, Concannon P, Onengut-Gumuscu S. Fine mapping and functional studies of risk variants for type 1 diabetes at chromosome 16p13.13. Diabetes. 63: 4360-8. PMID 25008175 DOI: 10.2337/Db13-1785  0.529
2014 Williams SR, Yang Q, Chen F, Liu X, Keene KL, Jacques P, Chen WM, Weinstein G, Hsu FC, Beiser A, Wang L, Bookman E, Doheny KF, Wolf PA, Zilka M, et al. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. Plos Genetics. 10: e1004214. PMID 24651765 DOI: 10.1371/Journal.Pgen.1004214  0.391
2014 Huang J, Huffman JE, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, ... ... Keene KL, et al. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1093-101. PMID 24578379 DOI: 10.1161/Atvbaha.113.302088  0.473
2014 Williams SR, Yang Q, Chen F, Liu X, Keene KL, Jacques P, Chen WM, Connelly JJ, Lillard TS, Weinstein G, Hsu FC, Beiser A, Wang L, Bookman E, Doheny KF, et al. Correction to Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke (PLoS Genet, (2014), 10, 7 (e1004571), 10.1371/journal.pgen.1004571) Plos Genetics. 10. DOI: 10.1371/Journal.Pgen.1004571  0.344
2013 Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, ... ... Keene KL, et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. American Journal of Human Genetics. 93: 545-54. PMID 23972371 DOI: 10.1016/J.Ajhg.2013.07.010  0.392
2012 Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, Rasheed A, Zeginigg M, Attia J, Baker R, Barlera S, Biffi A, Bookman E, Brott TG, Brown RD, et al. Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke? Stroke; a Journal of Cerebral Circulation. 43: 980-6. PMID 22363065 DOI: 10.1161/Strokeaha.111.632075  0.473
2012 Keene KL, Quinlan AR, Hou X, Hall IM, Mychaleckyj JC, Onengut-Gumuscu S, Concannon P. Evidence for two independent associations with type 1 diabetes at the 12q13 locus Genes and Immunity. 13: 66-70. PMID 21850031 DOI: 10.1038/Gene.2011.56  0.534
2010 Leak TS, Langefeld CD, Keene KL, Gallagher CJ, Lu L, Mychaleckyj JC, Rich SS, Freedman BI, Bowden DW, Sale MM. Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy. Bmc Medical Genetics. 11: 22. PMID 20144192 DOI: 10.1186/1471-2350-11-22  0.635
2009 Leak TS, Perlegas PS, Smith SG, Keene KL, Hicks PJ, Langefeld CD, Mychaleckyj JC, Rich SS, Kirk JK, Freedman BI, Bowden DW, Sale MM. Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans. Annals of Human Genetics. 73: 152-9. PMID 19183347 DOI: 10.1111/J.1469-1809.2008.00498.X  0.628
2008 Keene KL, Mychaleckyj JC, Leak TS, Smith SG, Perlegas PS, Divers J, Langefeld CD, Freedman BI, Bowden DW, Sale MM. Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease. Human Genetics. 124: 147-54. PMID 18654799 DOI: 10.1007/S00439-008-0532-6  0.557
2008 Hicks PJ, Staten JL, Palmer ND, Langefeld CD, Ziegler JT, Keene KL, Sale MM, Bowden DW, Freedman BI. Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease. American Journal of Nephrology. 28: 914-20. PMID 18580054 DOI: 10.1159/000141934  0.631
2008 Leak TS, Mychaleckyj JC, Smith SG, Keene KL, Gordon CJ, Hicks PJ, Freedman BI, Bowden DW, Sale MM. Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population. Human Genetics. 124: 63-71. PMID 18560894 DOI: 10.1007/S00439-008-0523-7  0.637
2008 Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Herrington DM, Freedman BI, Rich SS, Bowden DW, Sale MM. Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population. Human Genetics. 123: 333-41. PMID 18305958 DOI: 10.1007/S00439-008-0482-Z  0.639
2008 Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Freedman BI, Rich SS, Bowden DW, Sale MM. Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 57: 1057-62. PMID 18184924 DOI: 10.2337/Db07-0886  0.642
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Keene KL, et al. Contents Vol. 28, 2008 American Journal of Nephrology. 28. DOI: 10.1159/000163081  0.384
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Keene KL, et al. Subject Index Vol. 28, 2008 American Journal of Nephrology. 28: 1028-1030. DOI: 10.1159/000163080  0.393
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Keene KL, et al. Consultants for the American Journal of Nephrology 2008 American Journal of Nephrology. 28: 1023-1024. DOI: 10.1159/000163076  0.443
2007 Leak TS, Keene KL, Langefeld CD, Gallagher CJ, Mychaleckyj JC, Freedman BI, Bowden DW, Rich SS, Sale MM. Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population. Molecular Genetics and Metabolism. 92: 145-50. PMID 17618154 DOI: 10.1016/J.Ymgme.2007.05.014  0.641
2007 Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI. Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 56: 2638-42. PMID 17601994 DOI: 10.2337/Db07-0012  0.649
2007 Sale MM, Hsu FC, Palmer ND, Gordon CJ, Keene KL, Borgerink HM, Sharma AJ, Bergman RN, Taylor KD, Saad MF, Norris JM. The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study. Bmc Endocrine Disorders. 7: 1. PMID 17397545 DOI: 10.1186/1472-6823-7-1  0.392
2007 Gallagher CJ, Keene KL, Mychaleckyj JC, Langefeld CD, Hirschhorn JN, Henderson BE, Gordon CJ, Freedman BI, Rich SS, Bowden DW, Sale MM. Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations. Diabetes. 56: 675-84. PMID 17327435 DOI: 10.2337/Db06-0303  0.649
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