| Year |
Citation |
Score |
| 2023 |
Cai J, Jiang Y, Xu Y, Jiang Z, Young C, Li H, Ortiz-Guzman J, Zhuo Y, Li Y, Xu Y, Arenkiel BR, Tong Q. An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes. Neuron. PMID 38056455 DOI: 10.1016/j.neuron.2023.11.001 |
0.348 |
|
| 2023 |
Tu L, He Y, Xu Y. Anoctamin 4 defines glucose-inhibited neurons in the ventromedial hypothalamus. Neural Regeneration Research. 19: 1177-1178. PMID 37905852 DOI: 10.4103/1673-5374.385867 |
0.667 |
|
| 2023 |
Tu L, Bean JC, He Y, Liu H, Yu M, Liu H, Zhang N, Yin N, Han J, Scarcelli NA, Conde KM, Wang M, Li Y, Feng B, Gao P, ... ... Xu Y, et al. Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. The Journal of Clinical Investigation. PMID 37261917 DOI: 10.1172/JCI163391 |
0.76 |
|
| 2023 |
Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Lateral septum as a melanocortin downstream site in obesity development. Cell Reports. 42: 112502. PMID 37171957 DOI: 10.1016/j.celrep.2023.112502 |
0.401 |
|
| 2023 |
Li H, Xu Y, Jiang Y, Jiang Z, Otiz-Guzman J, Morrill JC, Cai J, Mao Z, Xu Y, Arenkiel BR, Huang C, Tong Q. The melanocortin action is biased toward protection from weight loss in mice. Nature Communications. 14: 2200. PMID 37069175 DOI: 10.1038/s41467-023-37912-z |
0.325 |
|
| 2023 |
Han Y, He Y, Harris L, Xu Y, Wu Q. Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity. Elife. 12. PMID 37043384 DOI: 10.7554/eLife.82649 |
0.423 |
|
| 2023 |
Liu H, He Y, Bai J, Zhang C, Zhang F, Yang Y, Luo H, Yu M, Liu H, Tu L, Zhang N, Yin N, Han J, Yan Z, Scarcelli NA, ... ... Xu Y, et al. Hypothalamic Grb10 enhances leptin signalling and promotes weight loss. Nature Metabolism. PMID 36593271 DOI: 10.1038/s42255-022-00701-x |
0.68 |
|
| 2022 |
He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, Lee DK, Yang Y, Cox AR, Keogh JM, Henning E, Bounds R, Perdikari A, Ayinampudi V, Wang C, ... ... Xu Y, et al. Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior. Nature Medicine. PMID 36536256 DOI: 10.1038/s41591-022-02106-5 |
0.559 |
|
| 2022 |
Yu M, Bean JC, Liu H, He Y, Yang Y, Cai X, Yu K, Pei Z, Liu H, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, ... ... Xu Y, et al. SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis. Cell & Bioscience. 12: 170. PMID 36210455 DOI: 10.1186/s13578-022-00907-2 |
0.777 |
|
| 2022 |
Pei Z, He Y, Bean JC, Yang Y, Liu H, Yu M, Yu K, Hyseni I, Cai X, Liu H, Qu N, Tu L, Conde KM, Wang M, Li Y, ... ... Xu Y, et al. Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Frontiers in Endocrinology. 13: 889122. PMID 36120438 DOI: 10.3389/fendo.2022.889122 |
0.805 |
|
| 2022 |
Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, ... ... Xu Y, et al. Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature Neuroscience. PMID 35729403 DOI: 10.1038/s41593-022-01116-3 |
0.698 |
|
| 2022 |
Liu H, Cai X, He Y, Xu Y. Hyperactivity of a midbrain dopamine to 5-HT circuit causes anorexia. Journal of Molecular Cell Biology. PMID 35612989 DOI: 10.1093/jmcb/mjac035 |
0.545 |
|
| 2022 |
Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, ... ... Xu Y, et al. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature Neuroscience. 25: 646-658. PMID 35501380 DOI: 10.1038/s41593-022-01062-0 |
0.735 |
|
| 2022 |
Mishra I, Xie WR, Bournat JC, He Y, Wang C, Silva ES, Liu H, Ku Z, Chen Y, Erokwu BO, Jia P, Zhao Z, An Z, Flask CA, He Y, ... Xu Y, et al. Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor. Cell Metabolism. PMID 35298903 DOI: 10.1016/j.cmet.2022.02.012 |
0.651 |
|
| 2022 |
Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, ... ... Xu Y, et al. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Science Advances. 8: eabk0185. PMID 35044814 DOI: 10.1126/sciadv.abk0185 |
0.79 |
|
| 2021 |
Yang Y, He Y, Liu H, Zhou W, Wang C, Xu P, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Fukuda M, Tong Q, Xu J, Sun Z, ... ... Xu Y, et al. Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Reports. 37: 110075. PMID 34879284 DOI: 10.1016/j.celrep.2021.110075 |
0.741 |
|
| 2021 |
Yoo ES, Li L, Jia L, Lord CC, Lee CE, Birnbaum SG, Vianna CR, Berglund ED, Cunningham KA, Xu Y, Sohn JW, Liu C. Gα-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents. Cell Reports. 37: 109997. PMID 34788630 DOI: 10.1016/j.celrep.2021.109997 |
0.682 |
|
| 2021 |
Tu L, Zhang N, Conde KM, Bean JC, Wang C, Xu Y. Free-floating Immunostaining of Mouse Brains. Journal of Visualized Experiments : Jove. PMID 34694284 DOI: 10.3791/62876 |
0.452 |
|
| 2021 |
Yan Z, He Y, Cai X, Shu G, Xu Y. Eating for hunger or pleasure: a Serotonin Model. Journal of Molecular Cell Biology. PMID 34480567 DOI: 10.1093/jmcb/mjab055 |
0.547 |
|
| 2021 |
Zhang N, Yan Z, Liu H, Yu M, He Y, Liu H, Liang C, Tu L, Wang L, Yin N, Han J, Scarcelli N, Yang Y, Wang C, Zeng T, ... ... Xu Y, et al. Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions. Frontiers in Physiology. 12: 714104. PMID 34393830 DOI: 10.3389/fphys.2021.714104 |
0.302 |
|
| 2021 |
He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, Liang C, Yang T, Yang Y, Yu K, Wang J, ... ... Xu Y, et al. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Molecular Psychiatry. PMID 34290371 DOI: 10.1038/s41380-021-01220-z |
0.769 |
|
| 2021 |
Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, ... ... Xu Y, et al. Author Correction: REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 595: E2. PMID 34131305 DOI: 10.1038/s41586-021-03654-5 |
0.631 |
|
| 2021 |
Han Y, Xia G, Srisai D, Meng F, He Y, Ran Y, He Y, Farias M, Hoang G, Tóth I, Dietrich MO, Chen MH, Xu Y, Wu Q. Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nature Communications. 12: 3525. PMID 34112797 DOI: 10.1038/s41467-021-23846-x |
0.699 |
|
| 2021 |
Han Y, Xia G, He Y, He Y, Farias M, Xu Y, Wu Q. A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation. Science Advances. 7. PMID 34039606 DOI: 10.1126/sciadv.abf8719 |
0.676 |
|
| 2021 |
He Y, Liu H, Yin N, Yang Y, Wang C, Yu M, Liu H, Liang C, Wang J, Tu L, Zhang N, Wang L, He Y, Fukuda M, Wu Q, ... ... Xu Y, et al. Barbadin potentiates long-term effects of lorcaserin on POMC neurons and weight loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34031163 DOI: 10.1523/JNEUROSCI.3210-20.2021 |
0.645 |
|
| 2021 |
Fan S, Xu Y, Lu Y, Jiang Z, Li H, Morrill JC, Cai J, Wu Q, Xu Y, Xue M, Arenkiel BR, Huang C, Tong Q. A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. Nature Communications. 12: 2662. PMID 33976218 DOI: 10.1038/s41467-021-22940-4 |
0.436 |
|
| 2021 |
Kaneko K, Lin HY, Fu Y, Saha PK, De la Puente-Gomez AB, Xu Y, Ohinata K, Chen P, Morozov A, Fukuda M. Rap1 in the VMH regulates glucose homeostasis. Jci Insight. PMID 33974562 DOI: 10.1172/jci.insight.142545 |
0.348 |
|
| 2021 |
Xia G, Han Y, Meng F, He Y, Srisai D, Farias M, Dang M, Palmiter RD, Xu Y, Wu Q. Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit. Molecular Psychiatry. PMID 33767348 DOI: 10.1038/s41380-021-01053-w |
0.664 |
|
| 2021 |
Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, ... ... Xu Y, et al. REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. PMID 33762728 DOI: 10.1038/s41586-021-03358-w |
0.665 |
|
| 2021 |
Wang C, Zhou W, He Y, Yang T, Xu P, Yang Y, Cai X, Wang J, Liu H, Yu M, Liang C, Yang T, Liu H, Fukuda M, Tong Q, ... ... Xu Y, et al. AgRP neurons trigger long-term potentiation and facilitate food seeking. Translational Psychiatry. 11: 11. PMID 33414382 DOI: 10.1038/s41398-020-01161-1 |
0.726 |
|
| 2020 |
Zhang Z, Reis FMCV, He Y, Park JW, DiVittorio JR, Sivakumar N, van Veen JE, Maesta-Pereira S, Shum M, Nichols I, Massa MG, Anderson S, Paul K, Liesa M, Ajijola OA, ... Xu Y, et al. Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice. Nature Communications. 11: 6378. PMID 33311503 DOI: 10.1038/s41467-020-20050-1 |
0.691 |
|
| 2020 |
Liu H, Xu Y, Hu F. AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis. Frontiers in Endocrinology. 11: 578830. PMID 33071984 DOI: 10.3389/fendo.2020.578830 |
0.33 |
|
| 2020 |
Liu H, Wang C, Yu M, Yang Y, He Y, Liu H, Liang C, Tu L, Zhang N, Wang L, Wang J, Liu F, Hu F, Xu Y. TPH2 in the dorsal Raphe nuclei regulates energy balance in a sex-dependent manner. Endocrinology. PMID 33034617 DOI: 10.1210/endocr/bqaa183 |
0.364 |
|
| 2020 |
Yang Y, Xu Y. The Central Melanocortin System and Human Obesity. Journal of Molecular Cell Biology. PMID 32976556 DOI: 10.1093/jmcb/mjaa048 |
0.367 |
|
| 2020 |
Kim ER, Xu Y, Cassidy RM, Lu Y, Yang Y, Tian J, Li DP, Van Drunen R, Ribas-Latre A, Cai ZL, Xue M, Arenkiel BR, Eckel-Mahan K, Xu Y, Tong Q. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nature Communications. 11: 3794. PMID 32732906 DOI: 10.1038/S41467-020-17578-7 |
0.467 |
|
| 2020 |
Zhu C, Jiang Z, Xu Y, Cai ZL, Jiang Q, Xu Y, Xue M, Arenkiel BR, Wu Q, Shu G, Tong Q. Profound and redundant functions of arcuate neurons in obesity development. Nature Metabolism. PMID 32719538 DOI: 10.1038/s42255-020-0229-2 |
0.367 |
|
| 2020 |
Yu K, He Y, Hyseni I, Pei Z, Yang Y, Xu P, Cai X, Liu H, Qu N, Liu H, He Y, Yu M, Liang C, Yang T, Wang J, ... ... Xu Y, et al. 17β-estradiol promotes acute refeeding in hungry mice by membrane-initiated ERα signaling. Molecular Metabolism. 101053. PMID 32712433 DOI: 10.1016/J.Molmet.2020.101053 |
0.684 |
|
| 2020 |
Fu Y, Kaneko K, Lin HY, Mo Q, Xu Y, Suganami T, Ravn P, Fukuda M. Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus. Endocrinology. PMID 32603429 DOI: 10.1210/Endocr/Bqaa102 |
0.377 |
|
| 2020 |
Zhu C, Xu Y, Jiang Z, Tian JB, Cassidy RM, Cai ZL, Shu G, Xu Y, Xue M, Arenkiel BR, Jiang Q, Tong Q. Disrupted hypothalamic CRH neuron responsiveness contributes to diet-induced obesity. Embo Reports. e49210. PMID 32462726 DOI: 10.15252/Embr.201949210 |
0.487 |
|
| 2020 |
Sun Z, Xu Y. Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain. Endocrinology. PMID 32449767 DOI: 10.1210/Endocr/Bqaa083 |
0.341 |
|
| 2020 |
da Silva Teixeira S, Harrison K, Uzodike M, Rajapakshe K, Coarfa C, He Y, Xu Y, Sisley S. Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. The Journal of Steroid Biochemistry and Molecular Biology. 200: 105690. PMID 32408067 DOI: 10.1016/J.Jsbmb.2020.105690 |
0.636 |
|
| 2020 |
He Y, Xu P, Wang C, Xia Y, Yu M, Yang Y, Yu K, Cai X, Qu N, Saito K, Wang J, Hyseni I, Robertson M, Piyarathna B, Gao M, ... ... Xu Y, et al. Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance. Nature Communications. 11: 2165. PMID 32358493 DOI: 10.1038/S41467-020-15982-7 |
0.765 |
|
| 2020 |
Wooton-Kee CR, Robertson M, Zhou Y, Dong B, Sun Z, Kim KH, Liu H, Xu Y, Putluri N, Saha P, Coarfa C, Moore DD, Nuotio-Antar AM. Metabolic dysregulation in the Wilson's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31924743 DOI: 10.1073/Pnas.1914267117 |
0.387 |
|
| 2020 |
He Y, Liu H, Xu Y. 140-OR: Inhibition of Serotonin 2c Receptor Internalization Potentiates Lorcaserin Effect on Body Weight Loss Diabetes. 69. DOI: 10.2337/Db20-140-Or |
0.512 |
|
| 2019 |
Qu N, He Y, Wang C, Xu P, Yang Y, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Sun Z, Fukuda M, Li Y, Tian Q, Xu Y. A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia. Molecular Psychiatry. PMID 31485012 DOI: 10.1038/S41380-019-0506-1 |
0.752 |
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| 2019 |
Kaneko K, Fu Y, Lin HY, Cordonier EL, Mo Q, Gao Y, Yao T, Naylor J, Howard V, Saito K, Xu P, Chen SS, Chen MH, Xu Y, Williams KW, et al. Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. The Journal of Clinical Investigation. 130. PMID 31403469 DOI: 10.1172/Jci126107 |
0.713 |
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| 2019 |
Xu Y, Lu Y, Cassidy RM, Mangieri LR, Zhu C, Huang X, Jiang Z, Justice NJ, Xu Y, Arenkiel BR, Tong Q. Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses. Nature Communications. 10: 3446. PMID 31371721 DOI: 10.1038/S41467-019-11399-Z |
0.354 |
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| 2019 |
Mangieri LR, Jiang Z, Lu Y, Xu Y, Cassidy RM, Justice N, Xu Y, Arenkiel BR, Tong Q. Defensive Behaviors Driven by a Hypothalamic-Ventral Midbrain Circuit. Eneuro. PMID 31331938 DOI: 10.1523/ENEURO.0156-19.2019 |
0.347 |
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| 2019 |
Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, ... ... Xu Y, et al. Author Correction: Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nature Neuroscience. PMID 31222187 DOI: 10.1038/S41593-019-0449-5 |
0.555 |
|
| 2019 |
Cordonier EL, Liu T, Saito K, Chen SS, Xu Y, Fukuda M. Luciferase Reporter Mice for Monitoring and Assessment of Hypothalamic Signaling of Expression. Journal of the Endocrine Society. 3: 1246-1260. PMID 31214662 DOI: 10.1210/Js.2019-00077 |
0.366 |
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| 2019 |
Wang C, Xu Y. Mechanisms for Sex Differences in Energy Homeostasis. Journal of Molecular Endocrinology. 62: R129-R143. PMID 31130779 DOI: 10.1530/Jme-18-0165 |
0.342 |
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| 2019 |
Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metabolism. 29: 1232. PMID 31067449 DOI: 10.1016/J.Cmet.2019.04.006 |
0.662 |
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| 2019 |
Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, ... ... Xu Y, et al. Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nature Communications. 10: 1718. PMID 30979869 DOI: 10.1038/S41467-019-08737-6 |
0.775 |
|
| 2019 |
Cassidy RM, Lu Y, Jere M, Tian JB, Xu Y, Mangieri LR, Felix-Okoroji B, Selever J, Xu Y, Arenkiel BR, Tong Q. A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues. Science Advances. 5: eaav1640. PMID 30854429 DOI: 10.1126/Sciadv.Aav1640 |
0.391 |
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| 2019 |
Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, ... ... Xu Y, et al. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nature Neuroscience. PMID 30664766 DOI: 10.1038/S41593-018-0311-1 |
0.663 |
|
| 2019 |
Xu P, He Y, Wang C, Yang Y, Cai X, Xu Y. 1796-P: A Ventral Medial Hypothalamus Estrogen Receptor a Neural Circuit Controlling Energy Expenditure Diabetes. 68. DOI: 10.2337/Db19-1796-P |
0.767 |
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| 2018 |
Yan H, Yang W, Zhou F, Li X, Pan Q, Shen Z, Han G, Newell-Fugate A, Tian Y, Majeti R, Liu W, Xu Y, Wu C, Allred K, Allred C, et al. Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1. Diabetes. PMID 30487265 DOI: 10.2337/Db18-0638 |
0.355 |
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| 2018 |
Xu Y, López M. Central regulation of energy metabolism by estrogens. Molecular Metabolism. PMID 29886181 DOI: 10.1016/J.Molmet.2018.05.012 |
0.334 |
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| 2018 |
Yu S, Cheng H, François M, Qualls-Creekmore E, Huesing C, He Y, Jiang Y, Gao H, Xu Y, Zsombok A, Derbenev AV, Nillni EA, Burk DH, Morrison CD, Berthoud HR, et al. Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife. 7. PMID 29761783 DOI: 10.7554/Elife.33505 |
0.668 |
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| 2018 |
Wang C, He Y, Xu P, Yang Y, Saito K, Xia Y, Yan X, Hinton A, Yan C, Ding H, Yu L, Shu G, Gupta R, Wu Q, Tong Q, ... ... Xu Y, et al. TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis. Nature Communications. 9: 1544. PMID 29670083 DOI: 10.1038/S41467-018-03796-7 |
0.756 |
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| 2018 |
Zhang P, Kuang H, He Y, Idiga SO, Li S, Chen Z, Yang Z, Cai X, Zhang K, Potthoff MJ, Xu Y, Lin JD. NRG1-Fc improves metabolic health via dual hepatic and central action. Jci Insight. 3. PMID 29515030 DOI: 10.1172/Jci.Insight.98522 |
0.669 |
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| 2018 |
Mangieri LR, Lu Y, Xu Y, Cassidy RM, Xu Y, Arenkiel BR, Tong Q. A neural basis for antagonistic control of feeding and compulsive behaviors. Nature Communications. 9: 52. PMID 29302029 DOI: 10.1038/S41467-017-02534-9 |
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| 2018 |
Yu S, Cheng H, François M, Qualls-Creekmore E, Huesing C, He Y, Jiang Y, Gao H, Xu Y, Zsombok A, Derbenev AV, Nillni EA, Burk DH, Morrison CD, Berthoud H, et al. Author response: Preoptic leptin signaling modulates energy balance independent of body temperature regulation Elife. DOI: 10.7554/Elife.33505.023 |
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| 2018 |
He Y, Xu P, Xia Y, Yang Y, Cai X, Hyseni I, Xu Y. Estrogen-Responsive Neurons in the Ventrolateral VMH Regulate Glucose Balance Diabetes. 67. DOI: 10.2337/Db18-374-Or |
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| 2018 |
Teixeira S, He Y, Xu Y, Sisley S. Vitamin D Enhances Insulin Sensitivity in Neurons Diabetes. 67. DOI: 10.2337/Db18-278-Lb |
0.627 |
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| 2018 |
Yan H, Zhou F, Yang W, Pan Q, Shen Z, Han G, Allred K, Allred C, Xu Y, Guo S. Estrogen Improves Insulin Sensitivity and Suppresses Hepatic Glucose Production via the Transcription Factor Foxo1 Diabetes. 67. DOI: 10.2337/Db18-1875-P |
0.354 |
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| 2018 |
Wang C, He Y, Xu P, Yang Y, Xu Y. TAp63 in Mature POMC Neurons Regulates Glucose and Energy Homeostasis Diabetes. 67. DOI: 10.2337/Db18-1796-P |
0.781 |
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0.696 |
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Bai J, Cervantes C, Liu J, He S, Zhou H, Zhang B, Cai H, Yin D, Hu D, Li Z, Chen H, Gao X, Wang F, O'Connor JC, Xu Y, et al. DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087318 DOI: 10.1073/Pnas.1708744114 |
0.338 |
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| 2017 |
Zhu C, Xu P, He Y, Yuan Y, Wang T, Cai X, Yu L, Yang L, Wu J, Wang L, Zhu X, Wang S, Gao P, Xi Q, Zhang Y, ... Xu Y, et al. Heparin Increases Food Intake through AgRP Neurons. Cell Reports. 20: 2455-2467. PMID 28877477 DOI: 10.1016/J.Celrep.2017.08.049 |
0.737 |
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| 2017 |
Kim ER, Fan S, Akhmedov D, Sun K, Lim H, O'Brien W, Xu Y, Mangieri LR, Zhu Y, Lee CC, Chung Y, Xia Y, Xu Y, Li F, Sun K, et al. Red blood cell β-adrenergic receptors contribute to diet-induced energy expenditure by increasing O2 supply. Jci Insight. 2. PMID 28724789 DOI: 10.1172/Jci.Insight.93367 |
0.335 |
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| 2017 |
Xu Y, Lu Y, Xu P, Mangieri LR, Isingrini E, Xu Y, Giros B, Tong Q. VMAT2-Mediated Neurotransmission from Midbrain Leptin Receptor Neurons in Feeding Regulation. Eneuro. 4. PMID 28560316 DOI: 10.1523/ENEURO.0083-17.2017 |
0.609 |
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| 2017 |
Wu CS, Bongmba OYN, Yue J, Lee JH, Lin L, Saito K, Pradhan G, Li DP, Pan HL, Xu A, Guo S, Xu Y, Sun Y. Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis. International Journal of Molecular Sciences. 18. PMID 28420089 DOI: 10.3390/Ijms18040832 |
0.496 |
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| 2017 |
Xu P, Zhu L, Saito K, Yang Y, Wang C, He Y, Yan X, Hyseni I, Tong Q, Xu Y. Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction. Metabolism: Clinical and Experimental. 70: 152-159. PMID 28403939 DOI: 10.1016/J.Metabol.2016.12.004 |
0.738 |
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| 2017 |
Xu Y, O'Malley BW, Elmquist JK. Brain nuclear receptors and body weight regulation. The Journal of Clinical Investigation. 127: 1172-1180. PMID 28218618 DOI: 10.1172/Jci88891 |
0.591 |
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| 2016 |
Hinton AO, Yang Y, Quick AP, Xu P, Reddy CL, Yan X, Reynolds CL, Tong Q, Zhu L, Xu J, Wehrens XH, Xu Y, Reddy AK. SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. Plos One. 11: e0168644. PMID 28006821 DOI: 10.1371/Journal.Pone.0168644 |
0.529 |
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| 2016 |
He Y, Shu G, Yang Y, Xu P, Xia Y, Wang C, Saito K, Hinton A, Yan X, Liu C, Wu Q, Tong Q, Xu Y. A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism. Cell Reports. 17: 1807-1818. PMID 27829152 DOI: 10.1016/J.Celrep.2016.10.044 |
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Kaneko K, Xu P, Cordonier EL, Chen SS, Ng A, Xu Y, Morozov A, Fukuda M. Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions. Cell Reports. 16: 3003-3015. PMID 27626668 DOI: 10.1016/J.Celrep.2016.08.039 |
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Xu P, He Y, Cao X, Valencia-Torres L, Yan X, Saito K, Wang C, Yang Y, Hinton A, Zhu L, Shu G, Myers MG, Wu Q, Tong Q, Heisler LK, ... Xu Y, et al. Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice. Biological Psychiatry. PMID 27516377 DOI: 10.1016/J.Biopsych.2016.06.005 |
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Sisley SR, Arble DM, Chambers AP, Gutierrez-Aguilar R, He Y, Xu Y, Gardner D, Moore DD, Seeley RJ, Sandoval DA. "Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight". Diabetes. PMID 27217488 DOI: 10.2337/Db16-0309 |
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Lee JH, Lin L, Xu P, Saito K, Wei Q, Meadows AG, Bongmba OY, Pradhan G, Zheng H, Xu Y, Sun Y. Neuronal deletion of ghrelin receptor almost completely prevents diet-induced obesity. Diabetes. PMID 27207529 DOI: 10.2337/Db15-1587 |
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Hu F, Xu Y, Liu F. Hypothalamic Roles of mTOR Complex I: Integration of nutrient and hormone signals to regulate energy homeostasis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00121.2016. PMID 27166282 DOI: 10.1152/ajpendo.00121.2016 |
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Hinton AO, He Y, Xia Y, Xu P, Yang Y, Saito K, Wang C, Yan X, Shu G, Henderson A, Clegg DJ, Khan SA, Reynolds C, Wu Q, Tong Q, ... Xu Y, et al. Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension. PMID 27091896 DOI: 10.1161/Hypertensionaha.116.07175 |
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Saito K, He Y, Yang Y, Zhu L, Wang C, Xu P, Hinton AO, Yan X, Zhao J, Fukuda M, Tong Q, Clegg DJ, Xu Y. PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Scientific Reports. 6: 23459. PMID 26988598 DOI: 10.1038/Srep23459 |
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Meng F, Han Y, Srisai D, Belakhov V, Farias M, Xu Y, Palmiter RD, Baasov T, Wu Q. New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976589 DOI: 10.1073/Pnas.1602049113 |
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Saito K, He Y, Yan X, Yang Y, Wang C, Xu P, Hinton AO, Shu G, Yu L, Tong Q, Xu Y. Visualizing estrogen receptor-α-expressing neurons using a new ERα-ZsGreen reporter mouse line. Metabolism: Clinical and Experimental. 65: 522-32. PMID 26975544 DOI: 10.1016/J.Metabol.2015.12.011 |
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Xu Y, Chang JT, Myers MG, Xu Y, Tong Q. Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release. Diabetes. PMID 26822087 DOI: 10.2337/Db15-1160 |
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Fan S, Dakshinamoorthy J, Kim ER, Xu Y, Huang C, Tong Q. An Indirect Action Contributes to C-Fos Induction in Paraventricular Hypothalamic Nucleus by Neuropeptide Y. Scientific Reports. 6: 19980. PMID 26813148 DOI: 10.1038/Srep19980 |
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Zhu L, Xu P, Cao X, Yang Y, Hinton AO, Xia Y, Saito K, Yan X, Zou F, Ding H, Wang C, Yan C, Saha P, Khan SA, Zhao J, ... Xu Y, et al. The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. en20151660. PMID 26375425 DOI: 10.1210/En.2015-1660 |
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Yan C, He Y, Xu Y, Shu G, Wang C, Yang Y, Saito K, Xu P, Hinton AO, Yan X, Yu L, Wu Q, Tso P, Tong Q, Xu Y. Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates POMC Neurons in the Arcuate Nucleus. Neuroendocrinology. PMID 26337236 DOI: 10.1159/000439436 |
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Xu P, Cao X, Xu Y. Targeting brain estrogen receptor for binge eating. Oncotarget. PMID 26309082 DOI: 10.18632/Oncotarget.5239 |
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Kim ER, Wu Z, Sun H, Xu Y, Mangieri LR, Xu Y, Tong Q. Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10440-50. PMID 26203139 DOI: 10.1523/Jneurosci.1110-15.2015 |
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Saito K, Cao X, He Y, Xu Y. Progress in the molecular understanding of central regulation of body weight by estrogens. Obesity (Silver Spring, Md.). 23: 919-26. PMID 25865677 DOI: 10.1002/Oby.21099 |
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Yan C, Yang Y, Saito K, Xu P, Wang C, Hinton AO, Yan X, Wu Q, Tong Q, Elmquist JK, Fukuda M, Xu Y. Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice. British Journal of Pharmacology. 172: 3510-21. PMID 25817043 DOI: 10.1111/Bph.13141 |
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Zhu L, Zou F, Yang Y, Xu P, Saito K, Othrell Hinton A, Yan X, Ding H, Wu Q, Fukuda M, Sun Z, Tong Q, Xu Y. Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology. 156: 2114-23. PMID 25807042 DOI: 10.1210/En.2014-1922 |
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Wu Z, Kim ER, Sun H, Xu Y, Mangieri LR, Li DP, Pan HL, Xu Y, Arenkiel BR, Tong Q. GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3312-8. PMID 25716832 DOI: 10.1523/Jneurosci.3720-14.2015 |
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Xu P, Cao X, Xu Y. Physical activity controlled by estrogen signals in the medial amygdala Receptors and Clinical Investigation. 2. DOI: 10.14800/Rci.975 |
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Scott MM, Xu Y, Elias CF, Williams KW. Central regulation of food intake, body weight, energy expenditure, and glucose homeostasis. Frontiers in Neuroscience. 8: 384. PMID 25520610 DOI: 10.3389/Fnins.2014.00384 |
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Shu G, Lu NS, Zhu XT, Xu Y, Du MQ, Xie QP, Zhu CJ, Xu Q, Wang SB, Wang LN, Gao P, Xi QY, Zhang YL, Jiang QY. Phloretin promotes adipocyte differentiation in vitro and improves glucose homeostasis in vivo. The Journal of Nutritional Biochemistry. 25: 1296-308. PMID 25283330 DOI: 10.1016/J.Jnutbio.2014.07.007 |
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Xu Y, Kim ER, Fan S, Xia Y, Xu Y, Huang C, Tong Q. Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists. Biochemical and Biophysical Research Communications. 451: 184-9. PMID 25065745 DOI: 10.1016/J.Bbrc.2014.07.079 |
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Xu Y, Wu Z, Sun H, Zhu Y, Kim ER, Lowell BB, Arenkiel BR, Xu Y, Tong Q. Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation. Cell Metabolism. 18: 860-70. PMID 24315371 DOI: 10.1016/J.Cmet.2013.11.003 |
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Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. The Journal of Clinical Investigation. 123: 5061-70. PMID 24177424 DOI: 10.1172/Jci70338 |
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Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J, Zeve D, D Hahner L, W Cox D, M Gent L, Xu Y, V Wang Z, A Khan S, Clegg DJ. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Molecular Metabolism. 2: 227-42. PMID 24049737 DOI: 10.1016/J.Molmet.2013.05.006 |
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Shi X, Zhou F, Li X, Chang B, Li D, Wang Y, Tong Q, Xu Y, Fukuda M, Zhao JJ, Li D, Burrin DG, Chan L, Guan X. Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metabolism. 18: 86-98. PMID 23823479 DOI: 10.1016/J.Cmet.2013.06.014 |
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Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in mice. Molecular and Cellular Biology. 33: 2327-38. PMID 23547261 DOI: 10.1128/Mcb.01421-12 |
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Zhu L, Yang Y, Xu P, Zou F, Yan X, Liao L, Xu J, O'Malley BW, Xu Y. Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology. 154: 150-8. PMID 23211707 DOI: 10.1210/En.2012-2007 |
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Tong Q, Xu Y. Central Leptin Regulation of Obesity and Fertility Current Obesity Reports. 1: 236-244. PMID 23243628 DOI: 10.1007/S13679-012-0025-8 |
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Xu Y, Nedungadiuli T, Gent L, Elias C, Elmquist JK, Clegg D. It's ALL in the Hypothalamus! Sex, Reproduction, and Obesity. Biology of Reproduction. 87: 34-34. DOI: 10.1093/Biolreprod/87.S1.34 |
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Xu Y, Faulkner LD, Hill JW. Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons. Frontiers in Endocrinology. 2: 98. PMID 22649394 DOI: 10.3389/Fendo.2011.00098 |
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Xu Y, Elmquist JK, Fukuda M. Central nervous control of energy and glucose balance: focus on the central melanocortin system. Annals of the New York Academy of Sciences. 1243: 1-14. PMID 22211889 DOI: 10.1111/J.1749-6632.2011.06248.X |
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Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 71: 488-97. PMID 21835345 DOI: 10.1016/J.Neuron.2011.06.012 |
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Kim KW, Zhao L, Donato J, Kohno D, Xu Y, Elias CF, Lee C, Parker KL, Elmquist JK. Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proceedings of the National Academy of Sciences of the United States of America. 108: 10673-8. PMID 21636788 DOI: 10.1073/Pnas.1102364108 |
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Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK, Zinn AR, Lowell BB, Elmquist JK. A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14630-4. PMID 21048120 DOI: 10.1523/Jneurosci.5412-09.2010 |
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Xu Y, Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate : a role for protein kinase A British Journal of Pharmacology. 148: 70-77. PMID 16501581 DOI: 10.1038/Sj.Bjp.0706698 |
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