| Year |
Citation |
Score |
| 2024 |
Jackson PEH, Dzhivhuho G, Huang J, Hammarskjold ML, Rekosh D. Measurement of HIV Rev-Rev Response Element Functional Activity. Methods in Molecular Biology (Clifton, N.J.). 2807: 175-194. PMID 38743229 DOI: 10.1007/978-1-0716-3862-0_13 |
0.461 |
|
| 2023 |
Jackson PEH, Holsey J, Turse L, Hammarskjold ML, Rekosh D. Rev-Rev Response Element Activity Selection Bias at the Human Immunodeficiency Virus Transmission Bottleneck. Open Forum Infectious Diseases. 10: ofad486. PMID 37854107 DOI: 10.1093/ofid/ofad486 |
0.411 |
|
| 2023 |
Jackson PEH, Holsey J, Turse L, Hammarskjold ML, Rekosh D. Rev-Rev Response Element Activity Selection Bias at the HIV Transmission Bottleneck. Biorxiv : the Preprint Server For Biology. PMID 37066242 DOI: 10.1101/2023.04.05.535732 |
0.418 |
|
| 2022 |
Dzhivhuho G, Holsey J, Honeycutt E, O'Farrell H, Rekosh D, Hammarskjold ML, Jackson PEH. HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev. Scientific Reports. 12: 18416. PMID 36319640 DOI: 10.1038/s41598-022-21714-2 |
0.461 |
|
| 2020 |
Mavhandu LG, Cheng H, Bor YC, Tebit DM, Hammarskjold ML, Rekosh D, Bessong PO. Development of a pseudovirus assay and evaluation to screen natural products for inhibition of HIV-1 subtype C reverse transcriptase. Journal of Ethnopharmacology. PMID 32360797 DOI: 10.1016/J.Jep.2020.112931 |
0.493 |
|
| 2020 |
Jackson PEH, Dzhivhuho G, Rekosh D, Hammarskjold ML. Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis. Current Hiv Research. PMID 31906839 DOI: 10.2174/1570162X18666200106112842 |
0.534 |
|
| 2019 |
Gamache A, Cronk JM, Nash WT, Puchalski P, Gillespie A, Wei H, Gray L, Hammarskjold ML, Xu W, Brown MG. Ly49R activation receptor drives self-MHC-educated NK cell immunity against cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843910 DOI: 10.1073/Pnas.1913064117 |
0.32 |
|
| 2019 |
Gray LR, Jackson RE, Jackson PEH, Bekiranov S, Rekosh D, Hammarskjöld ML. HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA. Retrovirology. 16: 40. PMID 31842941 DOI: 10.1186/S12977-019-0505-Y |
0.394 |
|
| 2019 |
Jackson PEH, Huang J, Sharma M, Rasmussen SK, Hammarskjold ML, Rekosh D. A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry. Scientific Reports. 9: 6467. PMID 31015546 DOI: 10.1038/S41598-019-42914-3 |
0.382 |
|
| 2019 |
Sherpa C, Jackson PEH, Gray LR, Anastos K, Le Grice SFJ, Hammarskjold ML, Rekosh D. Evolution of the HIV-1 RRE during natural infection reveals nucleotide changes that correlate with altered structure and increased activity over time. Journal of Virology. PMID 30867301 DOI: 10.1128/Jvi.02102-18 |
0.459 |
|
| 2019 |
Matume ND, Tebit DM, Gray LR, Turner SD, Rekosh D, Bessong PO, Hammarskjöld ML. Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa. Bmc Medical Genetics. 20: 21. PMID 30660178 DOI: 10.1186/S12881-018-0740-4 |
0.475 |
|
| 2018 |
Matume ND, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Bessong PO. Next generation sequencing reveals a high frequency of CXCR4 utilizing viruses in HIV-1 chronically infected drug experienced individuals in South Africa. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. PMID 29661652 DOI: 10.1016/J.Jcv.2018.02.008 |
0.503 |
|
| 2018 |
Rekosh D, Hammarskjold ML. Intron retention in viruses and cellular genes: Detention, border controls and passports. Wiley Interdisciplinary Reviews. Rna. PMID 29508942 DOI: 10.1002/Wrna.1470 |
0.363 |
|
| 2017 |
Etta EM, Mavhandu L, Manhaeve C, McGonigle K, Jackson P, Rekosh D, Hammarskjold ML, Bessong PO, Tebit DM. High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa. Aids Research and Therapy. 14: 36. PMID 28750647 DOI: 10.1186/S12981-017-0161-Z |
0.444 |
|
| 2017 |
Hammarskjold ML, Rekosh D. SR proteins: To shuttle or not to shuttle, that is the question. The Journal of Cell Biology. PMID 28600433 DOI: 10.1083/Jcb.201705009 |
0.301 |
|
| 2016 |
Li Y, Bor YC, Fitzgerald MP, Lee KS, Rekosh D, Hammarskjold ML. An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 co-factor. Molecular Biology of the Cell. PMID 27708137 DOI: 10.1091/Mbc.E16-07-0515 |
0.341 |
|
| 2016 |
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL. Effect of intercalator and Lewis acid-base branched peptide complex formation: boosting affinity towards HIV-1 RRE RNA. Medchemcomm. 7: 1436-1440. PMID 27453773 DOI: 10.1039/C6Md00171H |
0.419 |
|
| 2016 |
Jackson PE, Tebit DM, Rekosh DM, Hammarskjold ML. Rev-RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates. Aids Research and Human Retroviruses. PMID 27147495 DOI: 10.1089/AID.2016.0047 |
0.413 |
|
| 2016 |
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL. Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA. Bioorganic & Medicinal Chemistry. PMID 27091070 DOI: 10.1016/J.Bmc.2016.04.009 |
0.383 |
|
| 2015 |
Sherpa C, Rausch JW, Le Grice SF, Hammarskjold ML, Rekosh D. The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication. Nucleic Acids Research. 43: 4676-86. PMID 25855816 DOI: 10.1093/Nar/Gkv313 |
0.528 |
|
| 2015 |
Hammarskjöld ML. RNA and lessons from viruses. Rna (New York, N.Y.). 21: 632-3. PMID 25780169 DOI: 10.1261/Rna.050310.115 |
0.458 |
|
| 2015 |
Wang B, Rekosh D, Hammarskjold ML. Evolutionary conservation of a molecular machinery for export and expression of mRNAs with retained introns. Rna (New York, N.Y.). 21: 426-37. PMID 25605961 DOI: 10.1261/Rna.048520.114 |
0.32 |
|
| 2015 |
Jackson P, Tebit D, Rekosh D, Hammarskjold M. Human Immunodeficiency Virus (HIV)-1 Rev/RRE Functional Activity Variation Between Subtypes Is Largely Due to Changes in Rev Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.950 |
0.496 |
|
| 2013 |
Sloan EA, Kearney MF, Gray LR, Anastos K, Daar ES, Margolick J, Maldarelli F, Hammarskjold ML, Rekosh D. Limited nucleotide changes in the Rev response element (RRE) during HIV-1 infection alter overall Rev-RRE activity and Rev multimerization. Journal of Virology. 87: 11173-86. PMID 23926352 DOI: 10.1128/Jvi.01392-13 |
0.69 |
|
| 2012 |
Iweriebor BC, Mavhandu LG, Masebe T, Rekosh D, Hammarskjold ML, Mphahlele JM, Bessong PO. Molecular epidemiology of HIV in two highly endemic areas of northeastern South Africa. Archives of Virology. 157: 455-65. PMID 22189822 DOI: 10.1007/S00705-011-1180-Z |
0.475 |
|
| 2011 |
Hammarskjold ML, Rekosh D. A long-awaited structure is rev-ealed Viruses. 3: 484-492. PMID 21941623 DOI: 10.3390/V3050484 |
0.465 |
|
| 2011 |
Shuck-Lee D, Chang H, Sloan EA, Hammarskjold ML, Rekosh D. Single-nucleotide changes in the HIV Rev-response element mediate resistance to compounds that inhibit Rev function. Journal of Virology. 85: 3940-9. PMID 21289114 DOI: 10.1128/Jvi.02683-10 |
0.735 |
|
| 2009 |
Moore MD, Nikolaitchik OA, Chen J, Hammarskjöld ML, Rekosh D, Hu WS. Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses. Plos Pathogens. 5: e1000627. PMID 19834549 DOI: 10.1371/Journal.Ppat.1000627 |
0.464 |
|
| 2009 |
Ward AM, Rekosh D, Hammarskjold ML. Trafficking through the Rev/RRE pathway is essential for efficient inhibition of human immunodeficiency virus type 1 by an antisense RNA derived from the envelope gene. Journal of Virology. 83: 940-52. PMID 18971264 DOI: 10.1128/Jvi.01520-08 |
0.67 |
|
| 2008 |
Legiewicz M, Badorrek CS, Turner KB, Fabris D, Hamm TE, Rekosh D, Hammarskjöld ML, Le Grice SF. Resistance to RevM10 inhibition reflects a conformational switch in the HIV-1 Rev response element. Proceedings of the National Academy of Sciences of the United States of America. 105: 14365-70. PMID 18776047 DOI: 10.1073/Pnas.0804461105 |
0.479 |
|
| 2008 |
Shuck-Lee D, Chen FF, Willard R, Raman S, Ptak R, Hammarskjold ML, Rekosh D. Heterocyclic compounds that inhibit Rev-RRE function and human immunodeficiency virus type 1 replication. Antimicrobial Agents and Chemotherapy. 52: 3169-79. PMID 18625767 DOI: 10.1128/Aac.00274-08 |
0.471 |
|
| 2008 |
Olivieri KC, Scoggins RM, Broderick B, Powell ML, Alexander MA, Hammarskjöld ML, Rekosh D, Camerini D. Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142. Retrovirology. 5: 42. PMID 18510766 DOI: 10.1186/1742-4690-5-42 |
0.741 |
|
| 2007 |
Medeiros MS, Arruda EA, Guerrant RL, Brown C, Hammarskjold ML, Rekosh D, Lima AA. Genotype testing and antiretroviral resistance profiles from HIV-1 patients experiencing therapeutic failure in northeast Brazil. The Brazilian Journal of Infectious Diseases : An Official Publication of the Brazilian Society of Infectious Diseases. 11: 390-4. PMID 17873990 DOI: 10.1590/S1413-86702007000400003 |
0.407 |
|
| 2007 |
Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjold ML. The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element. The Journal of Biological Chemistry. 282: 19844-53. PMID 17513303 DOI: 10.1074/Jbc.M701660200 |
0.358 |
|
| 2007 |
Olivieri K, Scoggins RM, Bor YC, Matthews A, Mark D, Taylor JR, Chernauskas D, Hammarskjöld ML, Rekosh D, Camerini D. The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1. Virology. 358: 23-38. PMID 16999983 DOI: 10.1016/J.Virol.2006.08.027 |
0.742 |
|
| 2006 |
Bessong PO, Mphahlele J, Choge IA, Obi LC, Morris L, Hammarskjold ML, Rekosh DM. Resistance mutational analysis of HIV type 1 subtype C among rural South African drug-naive patients prior to large-scale availability of antiretrovirals. Aids Research and Human Retroviruses. 22: 1306-12. PMID 17209775 DOI: 10.1089/Aid.2006.22.1306 |
0.388 |
|
| 2006 |
Li Y, Bor YC, Misawa Y, Xue Y, Rekosh D, Hammarskjöld ML. An intron with a constitutive transport element is retained in a Tap messenger RNA. Nature. 443: 234-7. PMID 16971948 DOI: 10.1038/Nature05107 |
0.379 |
|
| 2006 |
Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjöld ML. The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron. Genes & Development. 20: 1597-608. PMID 16738405 DOI: 10.1101/Gad.1402306 |
0.359 |
|
| 2006 |
Lévesque L, Bor YC, Matzat LH, Jin L, Berberoglu S, Rekosh D, Hammarskjöld ML, Paschal BM. Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex. Molecular Biology of the Cell. 17: 931-43. PMID 16314397 DOI: 10.1091/Mbc.E04-07-0634 |
0.311 |
|
| 2004 |
Hammarskjöld ML. Regulation of retroviral RNA export. Seminars in Cell & Developmental Biology. 8: 83-90. PMID 15001110 DOI: 10.1006/Scdb.1996.0127 |
0.355 |
|
| 2004 |
Alexander M, Bor YC, Ravichandran KS, Hammarskjöld ML, Rekosh D. Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity. Journal of Virology. 78: 1685-96. PMID 14747534 DOI: 10.1128/Jvi.78.4.1685-1696.2004 |
0.354 |
|
| 2003 |
Jin L, Guzik BW, Bor YC, Rekosh D, Hammarskjöld ML. Tap and NXT promote translation of unspliced mRNA. Genes & Development. 17: 3075-86. PMID 14701875 DOI: 10.1101/Gad.1155703 |
0.352 |
|
| 2003 |
Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjöld ML. Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK. Molecular and Cellular Biology. 23: 92-103. PMID 12482964 DOI: 10.1128/Mcb.23.1.92-103.2003 |
0.388 |
|
| 2001 |
Lévesque L, Guzik B, Guan T, Coyle J, Black BE, Rekosh D, Hammarskjöld ML, Paschal BM. RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex. The Journal of Biological Chemistry. 276: 44953-62. PMID 11579093 DOI: 10.1074/Jbc.M106558200 |
0.333 |
|
| 2001 |
Chazal N, Singer G, Aiken C, Hammarskjöld ML, Rekosh D. Human immunodeficiency virus type 1 particles pseudotyped with envelope proteins that fuse at low pH no longer require Nef for optimal infectivity Journal of Virology. 75: 4014-4018. PMID 11264394 DOI: 10.1128/Jvi.75.8.4014-4018.2001 |
0.48 |
|
| 2001 |
Guzik BW, Levesque L, Prasad S, Bor YC, Black BE, Paschal BM, Rekosh D, Hammarskjöld ML. NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells. Molecular and Cellular Biology. 21: 2545-54. PMID 11259602 DOI: 10.1128/Mcb.21.7.2545-2554.2001 |
0.447 |
|
| 2001 |
Walk SF, Alexander M, Maier B, Hammarskjold ML, Rekosh DM, Ravichandran KS. Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation Journal of Virology. 75: 834-843. PMID 11134296 DOI: 10.1128/Jvi.75.2.834-843.2001 |
0.414 |
|
| 2000 |
Chien ML, Hammarskjöld ML. Epstein-Barr virus latent membrane protein (LMP1) induces specific NFκB complexes in human T-lymphoid cells Virus Research. 67: 17-30. PMID 10773315 DOI: 10.1016/S0168-1702(00)00121-0 |
0.329 |
|
| 1999 |
Hamm TE, Rekosh D, Hammarskjöld ML. Selection and characterization of human immunodeficiency virus type 1 mutants that are resistant to inhibition by the transdominant negative RevM10 protein Journal of Virology. 73: 5741-5747. PMID 10364325 DOI: 10.1128/Jvi.73.7.5741-5747.1999 |
0.507 |
|
| 1999 |
Helga-Maria C, Hammarskjöld ML, Rekosh D. An intact TAR element and cytoplasmic localization are necessary for efficient packaging of human immunodeficiency virus type 1 genomic RNA Journal of Virology. 73: 4127-4135. PMID 10196309 DOI: 10.1128/Jvi.73.5.4127-4135.1999 |
0.421 |
|
| 1997 |
Srinivasakumar N, Chazal N, Helga-Maria C, Prasad S, Hammarskjöld ML, Rekosh D. The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines Journal of Virology. 71: 5841-5848. PMID 9223473 DOI: 10.1128/Jvi.71.8.5841-5848.1997 |
0.444 |
|
| 1995 |
Dundr M, Leno GH, Hammarskjold ML, Rekosh D, Helga-Maria C, Olson MOJ. The roles of nucleolar structure and function in the subcellular location of the HIV-1 Rev protein Journal of Cell Science. 108: 2811-2823. PMID 7593322 |
0.34 |
|
| 1994 |
Hammarskjold ML, Li H, Rekosh D, Prasad S. Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron Journal of Virology. 68: 951-958. PMID 8289397 DOI: 10.1128/Jvi.68.2.951-958.1994 |
0.449 |
|
| 1994 |
Mak J, Jiang M, Wainberg MA, Hammarskjöld ML, Rekosh D, Kleiman L. Role of Pr160gag-pol in mediating the selective incorporation of tRNALys into human immunodeficiency virus type 1 particles Journal of Virology. 68: 2065-2072. PMID 7511167 DOI: 10.1128/Jvi.68.4.2065-2072.1994 |
0.493 |
|
| 1994 |
Ciccarelli RB, Winter LA, Lorenz R, Harris AL, Crawford AC, Bailey TR, Singh B, Hammarskjold ML, Rekosh D, Hughes JV. Inhibition of the cellular Rev response and HIV-1 replication by 8-alkyl- 2-(4-pyridyl)pyrido[2,3-d]pyrimidin-5(8H)-ones Antiviral Chemistry and Chemotherapy. 5: 169-175. DOI: 10.1177/095632029400500305 |
0.362 |
|
| 1992 |
Hammarskjold ML, Simurda MC. Epstein-Barr virus latent membrane protein transactivates the human immunodeficiency virus type 1 long terminal repeat through induction of NF- κB activity Journal of Virology. 66: 6496-6501. PMID 1404600 |
0.413 |
|
| 1991 |
Jeang KT, Chang Y, Berkhout B, Hammarskjöld ML, Rekosh D. Regulation of HIV expression: mechanisms of action of Tat and Rev Aids. 5. PMID 1845057 DOI: 10.1097/00002030-199101001-00002 |
0.469 |
|
| 1990 |
Lu X, Heimer J, Rekosh D, Hammarskjöld ML. U1 small nuclear RNA plays a direct role in the formation of a rev-regulated human immunodeficiency virus env mRNA that remains unspliced Proceedings of the National Academy of Sciences of the United States of America. 87: 7603-7607. DOI: 10.1073/Pnas.87.19.7598 |
0.318 |
|
| 1989 |
Hammarskjold ML, Heimer J, Hammarskjold B, Sangwan I, Albert L, Rekosh D. Regulation of human immunodeficiency virus env expression by the rev gene product Journal of Virology. 63: 1959-1966. PMID 2704072 DOI: 10.1128/Jvi.63.5.1959-1966.1989 |
0.325 |
|
| 1988 |
Rekosh D, Nygren A, Flodby P, Hammarskjöld ML, Wigzell H. Coexpression of human immunodeficiency virus envelope proteins and tat from a single simian virus 40 late replacement vector Proceedings of the National Academy of Sciences of the United States of America. 85: 334-338. PMID 2829181 DOI: 10.1073/Pnas.85.2.334 |
0.521 |
|
| 1986 |
Hammarskjöld ML, Wang SC, Klein G. High-level expression of the Epstein-Barr virus EBNA1 protein in CV1 cells and human lymphoid cells using a SV40 late replacement vector. Gene. 43: 41-50. PMID 3019836 DOI: 10.1016/0378-1119(86)90006-5 |
0.323 |
|
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