Welkin E. Johnson - Publications

Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Virology Biology, Epidemiology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nchioua R, Kmiec D, Gaba A, Stürzel CM, Follack T, Patrick S, Kirmaier A, Johnson WE, Hahn BH, Chelico L, Kirchhoff F. APOBEC3F constitutes a barrier to successful cross-species transmission of SIVsmm to humans. Journal of Virology. JVI0080821. PMID 34132575 DOI: 10.1128/JVI.00808-21  0.302
2019 Johnson WE, McCarthy KR. Complex Problems Require Ternary Solutions: Another Lesson from SIV Nef. Cell Host & Microbe. 26: 299-300. PMID 31513765 DOI: 10.1016/J.Chom.2019.08.016  0.338
2019 Johnson WE. Origins and evolutionary consequences of ancient endogenous retroviruses. Nature Reviews. Microbiology. PMID 30962577 DOI: 10.1038/S41579-019-0189-2  0.409
2019 Kirchhoff F, Johnson WE. Decision letter: Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection Elife. DOI: 10.7554/Elife.49875.Sa1  0.392
2018 Gifford RJ, Blomberg J, Coffin JM, Fan H, Heidmann T, Mayer J, Stoye J, Tristem M, Johnson WE. Nomenclature for endogenous retrovirus (ERV) loci. Retrovirology. 15: 59. PMID 30153831 DOI: 10.1186/S12977-018-0442-1  0.328
2018 Krupovic M, Blomberg J, Coffin JM, Dasgupta I, Fan H, Geering AD, Gifford R, Harrach B, Hull R, Johnson W, Kreuze JF, Lindemann D, Llorens C, Lockhart B, Mayer J, et al. : A new viral order unifying five families of reverse-transcribing viruses. Journal of Virology. PMID 29618642 DOI: 10.1128/Jvi.00515-18  0.337
2018 Khan AS, Bodem J, Buseyne F, Gessain A, Johnson W, Kuhn JH, Kuzmak J, Lindemann D, Linial ML, Löchelt M, Materniak-Kornas M, Soares MA, Switzer WM. Spumaretroviruses: Updated taxonomy and nomenclature. Virology. 516: 158-164. PMID 29407373 DOI: 10.1016/J.Virol.2017.12.035  0.445
2018 Ita S, Hill AK, Lam EC, Dufort FJ, Yang X, Newman R, Leviyang S, Fofana IB, Johnson WE. High-Resolution Sequencing of Viral Populations During Early SIV Infection Reveals Evolutionary Strategies for Rapid Escape from Emerging Env-Specific Antibody Responses. Journal of Virology. PMID 29343575 DOI: 10.1128/Jvi.01574-17  0.474
2017 Sinha A, Johnson WE. Retroviruses of the RDR superinfection interference group: ancient origins and broad host distribution of a promiscuous Env gene. Current Opinion in Virology. 25: 105-112. PMID 28837888 DOI: 10.1016/J.Coviro.2017.07.020  0.384
2017 Leviyang S, Griva I, Ita S, Johnson WE. A Penalized Regression Approach to Haplotype Reconstruction of Viral Populations Arising in Early HIV/SIV Infection. Bioinformatics (Oxford, England). PMID 28379346 DOI: 10.1093/Bioinformatics/Btx187  0.434
2016 Henzy JE, Gifford RJ, Kenaley CP, Johnson WE. An Intact Retroviral Gene Conserved in Spiny-Rayed Fishes for over 100 My. Molecular Biology and Evolution. PMID 28039384 DOI: 10.1093/Molbev/Msw262  0.352
2016 Wu F, Kirmaier A, White E, Ourmanov I, Whitted S, Matsuda K, Riddick N, Hall LR, Morgan JS, Plishka RJ, Buckler-White A, Johnson WE, Hirsch VM. TRIM5α Resistance Escape Mutations in Capsid are Transferable Between Simian Immunodeficiency Virus Strains. Journal of Virology. PMID 27681142 DOI: 10.1128/Jvi.01620-16  0.407
2016 McCarthy KR, Johnson WE, Kirmaier A. Phylogeny and History of the Lost SIV from Crab-Eating Macaques: SIVmfa. Plos One. 11: e0159281. PMID 27415779 DOI: 10.1371/Journal.Pone.0159281  0.432
2016 Henzy JE, Johnson WE. Phylogenetic sleuthing reveals pair of paralogous genes. Elife. 5. PMID 27244557 DOI: 10.7554/Elife.17224  0.311
2016 Diehl WE, Patel N, Halm K, Johnson WE. Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals. Elife. 5: e12704. PMID 26952212 DOI: 10.7554/Elife.12704  0.429
2016 Diehl WE, Patel N, Halm K, Johnson WE. Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals Elife. 5. DOI: 10.7554/eLife.12704  0.322
2015 Land AM, Wang J, Law EK, Aberle R, Kirmaier A, Krupp A, Johnson WE, Harris RS. Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif. Oncotarget. PMID 26544511 DOI: 10.18632/Oncotarget.5483  0.362
2015 McCarthy KR, Kirmaier A, Autissier P, Johnson WE. Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface. Plos Pathogens. 11: e1005085. PMID 26291613 DOI: 10.1371/Journal.Ppat.1005085  0.435
2015 Johnson WE. Endogenous Retroviruses in the Genomics Era Annual Review of Virology. 2: 135-159. DOI: 10.1146/Annurev-Virology-100114-054945  0.362
2014 Kirmaier A, Krupp A, Johnson WE. Understanding restriction factors and intrinsic immunity: insights and lessons from the primate lentiviruses. Future Virology. 9: 483-497. PMID 26543491 DOI: 10.2217/Fvl.14.25  0.408
2014 Lakhashe SK, Byrareddy SN, Zhou M, Bachler BC, Hemashettar G, Hu SL, Villinger F, Else JG, Stock S, Lee SJ, Vargas-Inchaustegui DA, Cofano EB, Robert-Guroff M, Johnson WE, Polonis VR, et al. Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus. Vaccine. 32: 6527-36. PMID 25245933 DOI: 10.1016/J.Vaccine.2014.08.065  0.432
2014 Kirmaier A, Johnson WE. Monkey-adapted HIV-1 highlights in vivo significance of restriction factors. Trends in Microbiology. 22: 486-7. PMID 25127418 DOI: 10.1016/J.Tim.2014.07.006  0.369
2014 McCarthy KR, Johnson WE. Plastic proteins and monkey blocks: how lentiviruses evolved to replicate in the presence of primate restriction factors. Plos Pathogens. 10: e1004017. PMID 24743473 DOI: 10.1371/Journal.Ppat.1004017  0.449
2014 Sholukh AM, Byrareddy SN, Shanmuganathan V, Hemashettar G, Lakhashe SK, Rasmussen RA, Watkins JD, Vyas HK, Thorat S, Brandstoetter T, Mukhtar MM, Yoon JK, Novembre FJ, Villinger F, Landucci G, ... ... Johnson WE, et al. Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose. Retrovirology. 11: 8. PMID 24444350 DOI: 10.1186/1742-4690-11-8  0.383
2014 Henzy JE, Gifford RJ, Johnson WE, Coffin JM. A novel recombinant retrovirus in the genomes of modern birds combines features of avian and mammalian retroviruses. Journal of Virology. 88: 2398-405. PMID 24352464 DOI: 10.1128/Jvi.02863-13  0.425
2013 Byrareddy SN, Ayash-Rashkovsky M, Kramer VG, Lee SJ, Correll M, Novembre FJ, Villinger F, Johnson WE, von Gegerfelt A, Felber BK, Ruprecht RM. Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques. Plos One. 8: e75556. PMID 24098702 DOI: 10.1371/Journal.Pone.0075556  0.386
2013 Krupp A, McCarthy KR, Ooms M, Letko M, Morgan JS, Simon V, Johnson WE. APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. Plos Pathogens. 9: e1003641. PMID 24098115 DOI: 10.1371/Journal.Ppat.1003641  0.426
2013 Wu F, Kirmaier A, Goeken R, Ourmanov I, Hall L, Morgan JS, Matsuda K, Buckler-White A, Tomioka K, Plishka R, Whitted S, Johnson W, Hirsch VM. TRIM5 alpha drives SIVsmm evolution in rhesus macaques. Plos Pathogens. 9: e1003577. PMID 23990789 DOI: 10.1371/Journal.Ppat.1003577  0.377
2013 Henzy JE, Johnson WE. Pushing the endogenous envelope. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120506. PMID 23938755 DOI: 10.1098/Rstb.2012.0506  0.342
2013 Johnson WE. Rapid adversarial co-evolution of viruses and cellular restriction factors. Current Topics in Microbiology and Immunology. 371: 123-51. PMID 23686234 DOI: 10.1007/978-3-642-37765-5_5  0.405
2013 McCarthy KR, Schmidt AG, Kirmaier A, Wyand AL, Newman RM, Johnson WE. Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity. Plos Pathogens. 9: e1003352. PMID 23675300 DOI: 10.1371/Journal.Ppat.1003352  0.331
2013 Manrique J, Piatak M, Lauer W, Johnson W, Mansfield K, Lifson J, Desrosiers R. Influence of mismatch of Env sequences on vaccine protection by live attenuated simian immunodeficiency virus. Journal of Virology. 87: 7246-54. PMID 23637396 DOI: 10.1128/Jvi.00798-13  0.395
2013 Butler K, Morgan JS, Hanson DL, Adams D, Garcia-Lerma JG, Heneine W, Ellenberger D, Hendry RM, McNicholl J, Johnson WE, Kersh EN. Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques. Aids Research and Human Retroviruses. 29: 1091-4. PMID 23461569 DOI: 10.1089/Aid.2012.0383  0.307
2013 Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, Alicea C, von Gegerfelt A, Huang W, Guan Y, Keele BF, Bess JW, Piatak M, Lifson JD, Williams WT, Shen X, ... ... Johnson W, et al. DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge. Proceedings of the National Academy of Sciences of the United States of America. 110: 2975-80. PMID 23359688 DOI: 10.1073/Pnas.1215393110  0.354
2012 Telenti A, Johnson WE. Host genes important to HIV replication and evolution. Cold Spring Harbor Perspectives in Medicine. 2: a007203. PMID 22474614 DOI: 10.1101/Cshperspect.A007203  0.411
2012 Lai L, Kwa SF, Kozlowski PA, Montefiori DC, Nolen TL, Hudgens MG, Johnson WE, Ferrari G, Hirsch VM, Felber BK, Pavlakis GN, Earl PL, Moss B, Amara RR, Robinson HL. SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses. Vaccine. 30: 1737-45. PMID 22178526 DOI: 10.1016/J.Vaccine.2011.12.026  0.355
2012 Rathinakumar R, Dutta M, Zhu P, Johnson WE, Roux KH. Binding of anti-membrane-proximal gp41 monoclonal antibodies to CD4-liganded and -unliganded human immunodeficiency virus type 1 and simian immunodeficiency virus virions. Journal of Virology. 86: 1820-31. PMID 22090143 DOI: 10.1128/Jvi.05489-11  0.366
2012 Zhang X, Sakawaki H, Miura T, Igarashi T, Horibata S, Yokomizo K, Matsuo K, Yamamoto N, Fofana I, Johnson W, Ohashi T, Shida H. Protection Against Highly Pathogenic SIV by BCG-SIV Recombinant Priming and Attenuated Replicating Vaccinia-SIV Recombinant Boosting Retrovirology. 9: 39. DOI: 10.1186/1742-4690-9-S2-P39  0.338
2011 Durudas A, Chen HL, Gasper MA, Sundaravaradan V, Milush JM, Silvestri G, Johnson W, Giavedoni LD, Sodora DL. Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques. Current Hiv Research. 9: 276-88. PMID 21861823 DOI: 10.2174/157016211797635928  0.356
2011 Reynolds MR, Sacha JB, Weiler AM, Borchardt GJ, Glidden CE, Sheppard NC, Norante FA, Castrovinci PA, Harris JJ, Robertson HT, Friedrich TC, McDermott AB, Wilson NA, Allison DB, Koff WC, ... Johnson WE, et al. The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge. Journal of Virology. 85: 9637-40. PMID 21734037 DOI: 10.1128/Jvi.05074-11  0.388
2011 Lakhashe SK, Velu V, Sciaranghella G, Siddappa NB, Dipasquale JM, Hemashettar G, Yoon JK, Rasmussen RA, Yang F, Lee SJ, Montefiori DC, Novembre FJ, Villinger F, Amara RR, Kahn M, ... ... Johnson WE, et al. Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges. Vaccine. 29: 5611-22. PMID 21693155 DOI: 10.1016/J.Vaccine.2011.06.017  0.421
2011 Fofana IB, Colantonio AD, Reeves RK, Connole MA, Gillis JM, Hall LR, Sato S, Audin CR, Evans DT, Shida H, Johnson RP, Johnson WE. Flow cytometry based identification of simian immunodeficiency virus Env-specific B lymphocytes. Journal of Immunological Methods. 370: 75-85. PMID 21689659 DOI: 10.1016/J.Jim.2011.05.010  0.417
2011 Lai L, Kwa S, Kozlowski PA, Montefiori DC, Ferrari G, Johnson WE, Hirsch V, Villinger F, Chennareddi L, Earl PL, Moss B, Amara RR, Robinson HL. Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine. The Journal of Infectious Diseases. 204: 164-73. PMID 21628671 DOI: 10.1093/Infdis/Jir199  0.389
2011 Schell JB, Rose NF, Bahl K, Diller K, Buonocore L, Hunter M, Marx PA, Gambhira R, Tang H, Montefiori DC, Johnson WE, Rose JK. Significant protection against high-dose simian immunodeficiency virus challenge conferred by a new prime-boost vaccine regimen. Journal of Virology. 85: 5764-72. PMID 21490100 DOI: 10.1128/Jvi.00342-11  0.405
2010 Johnson WE. Endless forms most viral. Plos Genetics. 6: e1001210. PMID 21124950 DOI: 10.1371/Journal.Pgen.1001210  0.439
2010 Bixby JG, Laur O, Johnson WE, Desrosiers RC. Diversity of envelope genes from an uncloned stock of SIVmac251. Aids Research and Human Retroviruses. 26: 1115-31. PMID 20836705 DOI: 10.1089/Aid.2010.0029  0.411
2010 Kirmaier A, Wu F, Newman RM, Hall LR, Morgan JS, O'Connor S, Marx PA, Meythaler M, Goldstein S, Buckler-White A, Kaur A, Hirsch VM, Johnson WE. TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species. Plos Biology. 8. PMID 20808775 DOI: 10.1371/Journal.Pbio.1000462  0.458
2009 Kirmaier A, Diehl W, Johnson WE. Acquisition and processing of nonhuman primate samples for genetic and phylogenetic analyses Methods. 49: 5-10. PMID 19508893 DOI: 10.1016/J.Ymeth.2009.05.015  0.313
2009 Jia B, Serra-Moreno R, Neidermyer W, Rahmberg A, Mackey J, Fofana IB, Johnson WE, Westmoreland S, Evans DT. Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2. Plos Pathogens. 5: e1000429. PMID 19436700 DOI: 10.1371/Journal.Ppat.1000429  0.446
2009 Johnson WE, Sawyer SL. Molecular evolution of the antiretroviral TRIM5 gene. Immunogenetics. 61: 163-76. PMID 19238338 DOI: 10.1007/S00251-009-0358-Y  0.351
2009 McNatt MW, Zang T, Hatziioannou T, Bartlett M, Fofana IB, Johnson WE, Neil SJ, Bieniasz PD. Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants. Plos Pathogens. 5: e1000300. PMID 19214216 DOI: 10.1371/Journal.Ppat.1000300  0.388
2008 Johnson WE. A proviral puzzle with a prosimian twist Proceedings of the National Academy of Sciences of the United States of America. 105: 20051-20052. PMID 19091949 DOI: 10.1073/Pnas.0811419106  0.421
2008 Yuste E, Bixby J, Lifson J, Sato S, Johnson W, Desrosiers R. Glycosylation of gp41 of simian immunodeficiency virus shields epitopes that can be targets for neutralizing antibodies. Journal of Virology. 82: 12472-86. PMID 18829751 DOI: 10.1097/01.Qai.0000351182.38541.97  0.415
2008 Sato S, Yuste E, Lauer WA, Chang EH, Morgan JS, Bixby JG, Lifson JD, Desrosiers RC, Johnson WE. Potent antibody-mediated neutralization and evolution of antigenic escape variants of simian immunodeficiency virus strain SIVmac239 in vivo. Journal of Virology. 82: 9739-52. PMID 18667507 DOI: 10.1128/Jvi.00871-08  0.389
2008 Newman RM, Hall L, Kirmaier A, Pozzi LA, Pery E, Farzan M, O'Neil SP, Johnson W. Evolution of a TRIM5-CypA splice isoform in old world monkeys Plos Pathogens. 4. PMID 18389077 DOI: 10.1371/Journal.Ppat.1000003  0.377
2008 Pecon-Slattery J, Troyer JL, Johnson WE, O'Brien SJ. Evolution of feline immunodeficiency virus in Felidae: implications for human health and wildlife ecology. Veterinary Immunology and Immunopathology. 123: 32-44. PMID 18359092 DOI: 10.1016/J.Vetimm.2008.01.010  0.319
2008 Lee AS, Gutiérrez-Arcelus M, Perry GH, Vallender EJ, Johnson WE, Miller GM, Korbel JO, Lee C. Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. Human Molecular Genetics. 17: 1127-36. PMID 18180252 DOI: 10.1093/Hmg/Ddn002  0.337
2007 Sato S, Johnson W. Antibody-mediated neutralization and simian immunodeficiency virus models of HIV/AIDS. Current Hiv Research. 5: 594-607. PMID 18045116 DOI: 10.2174/157016207782418515  0.459
2007 Newman RM, Johnson WE. A brief history of TRIM5α Aids Reviews. 9: 114-125. PMID 17694678  0.309
2007 Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors. Journal of Virology. 81: 6548-62. PMID 17409160 DOI: 10.1128/Jvi.02749-06  0.428
2007 Johnson WE. Host genetic variation and susceptibility to primate lentiviruses Future Hiv Therapy. 1: 399-413. DOI: 10.2217/17469600.1.4.399  0.433
2006 Newman RM, Hall L, Connole M, Chen GL, Sato S, Yuste E, Diehl W, Hunter E, Kaur A, Miller GM, Johnson WE. Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha. Proceedings of the National Academy of Sciences of the United States of America. 103: 19134-9. PMID 17142324 DOI: 10.1073/Pnas.0605838103  0.306
2006 Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. Journal of Virology. 80: 3030-41. PMID 16501112 DOI: 10.1128/Jvi.80.6.3030-3041.2006  0.391
2005 Yuste E, Johnson W, Pavlakis GN, Desrosiers RC. Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus. Journal of Virology. 79: 12455-63. PMID 16160173 DOI: 10.1128/Jvi.79.19.12455-12463.2005  0.369
2003 Johnson WE, Sanford H, Schwall L, Burton DR, Parren PW, Robinson JE, Desrosiers RC. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. Journal of Virology. 77: 9993-10003. PMID 12941910 DOI: 10.1128/Jvi.77.18.9993-10003.2003  0.497
2003 Johnson WE, Lifson JD, Lang SM, Johnson RP, Desrosiers RC. Importance of B-cell responses for immunological control of variant strains of simian immunodeficiency virus. Journal of Virology. 77: 375-81. PMID 12477842 DOI: 10.1128/Jvi.77.1.375-381.2003  0.386
2002 Johnson WE, Morgan J, Reitter J, Puffer BA, Czajak S, Doms RW, Desrosiers RC. A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope. Journal of Virology. 76: 2075-86. PMID 11836385 DOI: 10.1128/Jvi.76.5.2075-2086.2002  0.381
2002 Johnson WE, Desrosiers RC. Viral persistence: HIV's strategies of immune system evasion. Annual Review of Medicine. 53: 499-518. PMID 11818487 DOI: 10.1146/Annurev.Med.53.082901.104053  0.47
2001 Johnson WE, Sauvron JM, Desrosiers RC. Conserved, N-linked carbohydrates of human immunodeficiency virus type 1 gp41 are largely dispensable for viral replication Journal of Virology. 75: 11426-11436. PMID 11689624 DOI: 10.1128/Jvi.75.23.11426-11436.2001  0.365
2000 Auerbach MR, Czajak SC, Johnson WE, Desrosiers RC, Alexander L. Species specificity of macaque rhadinovirus glycoprotein B sequences Journal of Virology. 74: 584-590. PMID 10590154 DOI: 10.1128/Jvi.74.1.584-590.2000  0.318
1993 LaVail JH, Johnson WE, Spencer LC. Immunohistochemical identification of trigeminal ganglion neurons that innervate the mouse cornea: relevance to intercellular spread of herpes simplex virus. The Journal of Comparative Neurology. 327: 133-40. PMID 7679419 DOI: 10.1002/Cne.903270111  0.315
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