Kimberley A. Lentz, Ph.D. - Related publications

2000 University of Maryland School of Medicine, Baltimore, MD, United States 
Pharmacy, Pharmaceutical Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Monroe JJ, Tanis KQ, Podtelezhnikov AA, Nguyen T, Mahotka S, Lynch D, Evers R, Palamanda J, Miller R, Pippert T, Cabalu T, Johnson TE, Aslamkhan AG, Kang W, Tamburino AM, et al. Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development that informs Chemically Reactive Metabolite formation and Potential for Drug Induced Liver Injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32559301 DOI: 10.1093/toxsci/kfaa088   
2020 Mahajan MK, Rivera EJ, Sun HH, Nagilla R, DeMartino MP, Haile PA, Casillas LN, Marquis RW, Votta BJ, Bertin J, Reilly MA. Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pharmacokinetics. Journal of Pharmaceutical Sciences. PMID 32565354 DOI: 10.1016/j.xphs.2020.06.013   
2020 Masoumi S, Esmaeili A. New method of creating hybrid of buprenorphine loaded rifampin/polyethylene glycol/alginate nanoparticles. International Journal of Biological Macromolecules. 159: 204-212. PMID 32416296 DOI: 10.1016/j.ijbiomac.2020.05.065   
2020 Abou Baker DH, Ibrahim BMM, Hassan NS, Yousuf AF, Gengaihi SE. Exploiting seeds and their secondary metabolites in the management of Alzheimer disease. Toxicology Reports. 7: 723-729. PMID 32551234 DOI: 10.1016/j.toxrep.2020.06.001   
2020 Chai B, Li Y, Yu SS. Three new antinociceptive diterpenoids from the roots of . Journal of Asian Natural Products Research. 1-10. PMID 32536209 DOI: 10.1080/10286020.2020.1777545   
2020 Bhuiyan MMR, Bhuiya NMMA, Hasan MN, Nahar UJ. and evaluation of antinociceptive activities of seed extract from the plant. Heliyon. 6: e03962. PMID 32426548 DOI: 10.1016/j.heliyon.2020.e03962   
2020 Hudson AR, Santora VJ, Petroski RE, Almos TA, Anderson G, Barido R, Basinger J, Bellows CL, Bookser BC, Broadbent NJ, Cabebe C, Chai CK, Chen M, Chow S, Chung M, et al. Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties. Bioorganic & Medicinal Chemistry Letters. 30: 127214. PMID 32527538 DOI: 10.1016/j.bmcl.2020.127214   
2020 Tareq AM, Farhad S, Neshar Uddin ABM, Hoque M, Nasrin MS, Uddin MMR, Hasan M, Sultana A, Munira MS, Lyzu C, Moazzem Hossen SM, Ali Reza ASM, Emran TB. Chemical profiles, pharmacological properties, and studies provide new insights on . Heliyon. 6: e04061. PMID 32529070 DOI: 10.1016/j.heliyon.2020.e04061   
2020 Sidhu A, Singla N, Lonare M, Mahal AK. Effect of quinestrol on body weight, vital organs, biochemicals and genotoxicity in adult male lesser bandicoot rat, Bandicota bengalensis. Pesticide Biochemistry and Physiology. 165: 104544. PMID 32359538 DOI: 10.1016/j.pestbp.2020.02.010   
2020 Hong LL, Wang Q, Zhao YT, Zhang S, Zhang KQ, Chen WD, Peng C, Liu L, Wang HS. Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS. Biomed Research International. 2020: 4816209. PMID 32461991 DOI: 10.1155/2020/4816209   
2020 Llano López LH, Melonari P, Olguin M, Fraile MD, Landa AI, Gargiulo PA. Effects of atenolol injected into the nucleus accumbens septi in rats in the elevated plus-maze test. Journal of Basic and Clinical Physiology and Pharmacology. PMID 32598313 DOI: 10.1515/jbcpp-2020-0003   
2020 Menezes TM, Gaião WDC, de Almeida Sousa Lima LC, da Silva AKB, Lima LWS, de Souza Pereira ÁM, da Silva LC, da Silva VL, de Souza Franco E, Paz ST, Maia CS, da Silva TMS, de Sousa Maia MB. Evaluation of acute oral toxicity, embryotoxicity and cytotoxicity of the polar fraction of aerial parts extract. Toxicology Research. 9: 19-27. PMID 32440335 DOI: 10.1093/toxres/tfz002   
2020 Kim B, Jha S, Seo JH, Jeong CH, Lee S, Lee S, Seo YH, Park B. MeBib Suppressed Methamphetamine Self-Administration Response via Inhibition of BDNF/ERK/CREB Signal Pathway in the Hippocampus. Biomolecules & Therapeutics. PMID 32466633 DOI: 10.4062/biomolther.2020.041   
2020 Wang MN, Kuang Y, Gong LY, Hua Y, Pei Q, Guo CX, Cao Y, Huang J, Yang GP. First-in-human, phase I single-ascending-dose study of the safety, pharmacokinetics, and relative bioavailability of selatinib, a dual EGFR-ErbB2 inhibitor in healthy subjects. Investigational New Drugs. PMID 32535812 DOI: 10.1007/s10637-020-00959-6   
2020 Ivy D, Palese F, Vozella V, Fotio Y, Yalcin A, Ramirez G, Mears D, Wynn G, Piomelli D. Cannabinoid CB receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32375160 DOI: 10.1038/s41386-020-0696-x   
2020 Chan K, Ledesma KR, Wang W, Tam VH. Characterization of Amikacin Drug Exposure and Nephrotoxicity in an Animal Model. Antimicrobial Agents and Chemotherapy. PMID 32571819 DOI: 10.1128/AAC.00859-20   
2020 Knych HK, Weiner D, Arthur R, Baden R, McKemie DS, Kass PH. Serum Concentrations, Pharmacokinetic/Pharmacodynamic Modeling and Effects of Dexamethasone on Inflammatory Mediators following Intravenous and Oral Administration to Exercised Horses. Drug Testing and Analysis. PMID 32436346 DOI: 10.1002/dta.2862   
2020 He F, Jiang T, Hong S, Wang L, Chen W, Liu L. Effect of You-Gui Yin on the Activities of Seven Cytochrome P450 Isozymes in Rats. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 9784946. PMID 32508959 DOI: 10.1155/2020/9784946   
2020 Aleem A, Janbaz KH, Imran I, Wahid M, Bibi S, Afzal K, Asad MHHB. Antiplatelet Aggregation, Cardiotonic, Anti-Inflammatory, Antioxidant, and Calcium Channel Antagonistic Potentials of Buch. Biomed Research International. 2020: 2096947. PMID 32566667 DOI: 10.1155/2020/2096947   
2020 Lee J, Mandava S, Ahn SH, Bae MA, So KS, Kwon KS, Kim HP. Potential Moracin M Prodrugs Strongly Attenuate Airway Inflammation . Biomolecules & Therapeutics. PMID 32388942 DOI: 10.4062/biomolther.2019.212   
2020 Hou YN, Wang YR, Zheng CH, Feng K. Biotransformation of 5-hydroxymethylfurfural into 2,5-dihydroxymethylfuran by Ganoderma sessile and toxicological assessment of both compounds. Amb Express. 10: 88. PMID 32394214 DOI: 10.1186/s13568-020-01023-5   
2020 Truver MT, Smith CR, Garibay N, Kopajtic TA, Swortwood MJ, Baumann MH. Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats. Neuropharmacology. 108195. PMID 32533977 DOI: 10.1016/j.neuropharm.2020.108195   
2020 Singh P, Walia V. Anxiolytic like effect of L-Carnitine in mice: Evidences for the involvement of NO-sGC-cGMP signaling pathway. Behavioural Brain Research. 112689. PMID 32417275 DOI: 10.1016/j.bbr.2020.112689   
2020 Zakaria ZA, Kamisan FH, Kek TL, Salleh MZ. Hepatoprotective and antioxidant activities of leaf extract against paracetamol-induced liver intoxication in rats. Pharmaceutical Biology. 58: 478-489. PMID 32476526 DOI: 10.1080/13880209.2020.1764058   
2020 Park Y, Park MH, Byeon JJ, Shin SH, Lee BI, Choi JM, Kim N, Park SJ, Park MJ, Lim JH, Shin YG. Assessment of Pharmacokinetics and Metabolism Profiles of SCH 58261 in Rats Using Liquid Chromatography-Mass Spectrometric Method. Molecules (Basel, Switzerland). 25. PMID 32397307 DOI: 10.3390/molecules25092209   
2020 Marie S, Hernández-Lozano I, Breuil L, Saba W, Novell A, Gennisson JL, Langer O, Truillet C, Tournier N. Validation of Pharmacological Protocols for Targeted Inhibition of Canalicular MRP2 Activity in Hepatocytes Using [Tc]mebrofenin Imaging in Rats. Pharmaceutics. 12. PMID 32471244 DOI: 10.3390/pharmaceutics12060486   
2020 Jiang N, Zhang M, Meng X, Sun B. Effects of curcumin on the pharmacokinetics of amlodipine in rats and its potential mechanism. Pharmaceutical Biology. 58: 465-468. PMID 32432949 DOI: 10.1080/13880209.2020.1764060   
2020 Belhadj S, Keskes H, Apel C, Roussi F, Litaudon M, Hentati O, Allouche N. Anti-diabetic and lipid-lowering effects of drimane sesquiterpenoids isolated from Zygogynum pancheri. Chemico-Biological Interactions. 109167. PMID 32603660 DOI: 10.1016/j.cbi.2020.109167   
2020 Géa LP, da Rosa ED, Panizzutti BS, de Aguiar ÉZ, de Oliveira LF, Ferrari P, Piato A, Gomez R, Colombo R, Rosa AR. Reduction of hippocampal IL-6 levels in LPS-injected rats following acute exendin-4 treatment. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 32363414 DOI: 10.1007/s00210-020-01867-5   
2020 Vanhoutte F, Liang S, Ruddy M, Zhao A, Drewery T, Wang Y, DelGizzi R, Forleo-Neto E, Rajadhyaksha M, Herman G, Davis JD. Pharmacokinetics and Pharmacodynamics of Garetosmab (Anti-Activin A): Results From a First-in-Human Phase 1 Study. Journal of Clinical Pharmacology. PMID 32557665 DOI: 10.1002/jcph.1638   
2020 Phipps KR, Sulaiman C, Simon R, Holalagoudar S, Kohchi C, Nakata Y. Subchronic (90-day) toxicity assessment of Somacy-FP100, a lipopolysaccharide-containing fermented wheat flour extract from Pantoea agglomerans. Journal of Applied Toxicology : Jat. PMID 32346895 DOI: 10.1002/jat.3987   
2020 Islam S, Alam MB, Ahmed A, Lee S, Lee SH, Kim S. Identification of secondary metabolites in Averrhoa carambola L. bark by high-resolution mass spectrometry and evaluation for α-glucosidase, tyrosinase, elastase, and antioxidant potential. Food Chemistry. 332: 127377. PMID 32619942 DOI: 10.1016/j.foodchem.2020.127377   
2020 Grundy JS, King CD, Adams JW, Cabell CH. Safety, tolerability, and pharmacokinetics of the selective prostacyclin receptor agonist ralinepag in single and multiple dosing studies of an immediate-release oral formulation in healthy volunteers. Pulmonary Circulation. 10: 2045894020922814. PMID 32489643 DOI: 10.1177/2045894020922814   
2020 Hossain M, Tiffany C, Raychaudhuri A, Nguyen D, Tai G, Alcorn H, Preston RA, Marbury T, Dumont E. Pharmacokinetics of Gepotidacin in Renal Impairment. Clinical Pharmacology in Drug Development. PMID 32429000 DOI: 10.1002/cpdd.807   
2020 Gomeni R, Xu T, Gao X, Bressolle-Gomeni F. Model based approach for estimating the dosage regimen of indomethacin a potential antiviral treatment of patients infected with SARS CoV-2. Journal of Pharmacokinetics and Pharmacodynamics. PMID 32435882 DOI: 10.1007/s10928-020-09690-4   
2020 Ikram M, Beshbishy AM, Kifayatullah M, Olukanni A, Zahoor M, Naeem M, Amin M, Shah M, Abdelaziz AS, Ullah R, Mothana RA, Siddiqui NA, Batiha GE. Chemotherapeutic Potential of Root Extract as Antidiarrheal and In Vitro Antibacterial Activities. Antibiotics (Basel, Switzerland). 9. PMID 32370087 DOI: 10.3390/antibiotics9050226   
2020 Johnson M, Jewell RC, Gan J, Dumont E, Burns O, Johns BA. A Phase 1 Study to Assess the Relative Bioavailability, Food Effect, and Safety of a Tablet Formulation of GSK2838232, a Novel HIV Maturation Inhibitor in Healthy Participants After Single and Repeated Doses. Clinical Pharmacology in Drug Development. PMID 32558338 DOI: 10.1002/cpdd.820   
2020 Cengiz O, Baran M, Balcioglu E, Suna PA, Bilgici P, Goktepe O, Onder GO, Goc R, Yay A. Use of selenium to ameliorate doxorubicin induced hepatotoxicity by targeting pro-inflammatory cytokines. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 1-9. PMID 32400214 DOI: 10.1080/10520295.2020.1760353   
2020 Ames FQ, Bracht L, Schneider LCL, Rocha BA, Santos GA, Lima EP, Rocha EMT, Cuman RKN, Bersani-Amado CA. Anti-inflammatory Effect of Low-Dose Anethole and Ibuprofen Combination Is Accompanied by Partial Prevention of Hepatic Metabolic Changes in Arthritic Rats. Inflammation. PMID 32424605 DOI: 10.1007/s10753-020-01241-w   
2020 Yang J, Sun J, Castellanos DM, Pardridge WM, Sumbria RK. Eliminating Fc N-linked glycosylation and its impact on dosing consideration for a transferrin receptor antibody-erythropoietin fusion protein in mice. Molecular Pharmaceutics. PMID 32579360 DOI: 10.1021/acs.molpharmaceut.0c00231   
2020 Cho CW, Song YR, Lim WC, Hwang YH, Rhee YK, Choi JW, Lee KT, Hong HD. Acute Oral Toxicity and Genotoxicity of Polysaccharide Fraction from Young Barley Leaves ( L.). Foods (Basel, Switzerland). 9. PMID 32575580 DOI: 10.3390/foods9060809   
2020 Shittu O, Opeyemi OA, Salawu MK, Ashiru AA, Medaiyese SA, Asogwa N, Sheba KF, Kadir RA, Aremu OI, Ajibaye O. Alterations in histological, biochemical and hematological parameters in Plasmodium berghei NK-65 infected balb/c mice treated with Bridelia ferruginea stem bark extract. Journal of Complementary & Integrative Medicine. PMID 32427117 DOI: 10.1515/jcim-2018-0219   
2020 Wu Y, Tian YJ, Le ML, Zhang SR, Zhang C, Huang MX, Jiang MY, Zhang B, Luo HB. Discovery of Novel Selective and Orally Bioavailable Phosphodiesterase-1 Inhibitors for the Efficient Treatment of Idiopathic Pulmonary Fibrosis. Journal of Medicinal Chemistry. PMID 32603117 DOI: 10.1021/acs.jmedchem.0c00711   
2020 Zenklusen I, Muehlan C, Ulc I, Liška J, Dingemanse J. The dual orexin receptor antagonist daridorexant does not affect the pharmacokinetics of the BCRP substrate rosuvastatin. Clinical and Experimental Pharmacology & Physiology. PMID 32603512 DOI: 10.1111/1440-1681.13370   
2020 Hübner MP, Martin C, Specht S, Koschel M, Dubben B, Frohberger SJ, Ehrens A, Fendler M, Struever D, Mitre E, Vallarino-Lhermitte N, Gokool S, Lustigman S, Schneider M, Townson S, et al. Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro. Plos Neglected Tropical Diseases. 14: e0008427. PMID 32628671 DOI: 10.1371/journal.pntd.0008427   
2020 Kim HY, Zuo G, Lee SK, Lim SS. Acute and subchronic toxicity study of nonpolar extract of licorice roots in mice. Food Science & Nutrition. 8: 2242-2250. PMID 32405381 DOI: 10.1002/fsn3.1465   
2020 Ayza MA, Balasubramanian R, Berhe AH. Cardioprotective Effect of Stem Bark Extract and Solvent Fractions on Cyclophosphamide-Induced Cardiotoxicity in Rats. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 8467406. PMID 32328140 DOI: 10.1155/2020/8467406   
2020 Joseph A, Nm J, Kumar S, S SD, Maliakel B, Im K. Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili () extract (Capsifen®): Acute and sub-chronic studies. Toxicology Reports. 7: 602-609. PMID 32435598 DOI: 10.1016/j.toxrep.2020.04.014   
2020 Ferrière S, Peyron I, Christophe OD, Kawecki C, Casari C, Muczynski V, Nathwani AC, Kauskot A, Lenting PJ, Denis CV. A hemophilia A mouse model for the in vivo assessment of Emicizumab function. Blood. PMID 32369559 DOI: 10.1182/blood.2019004334   
2020 Liu Y, Wang B, Xu H, Ge W, Xie Y, Zhang M, Kong M, Fan W. Synergistic Effect of Diacylglycerol and Vitamin D in Ameliorating Dextran Sodium Sulfate-Induced Colitis in Rats. Lipids. PMID 32419184 DOI: 10.1002/lipd.12248