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Bryan R. Cullen - Publications

Affiliations: 
Molecular Genetics and Microbiology Duke University, Durham, NC 
Area:
Molecular Biology, Virology Biology
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294 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Martinez Campos C, Tsai K, Courtney DG, Bogerd HP, Holley CL, Cullen BR. Mapping of pseudouridine residues on viral and cellular transcripts using a novel antibody-based technique. Rna (New York, N.Y.). PMID 34376564 DOI: 10.1261/rna.078940.121  0.716
2021 Tsai K, Bogerd HP, Kennedy EM, Emery A, Swanstrom R, Cullen BR. Epitranscriptomic addition of mA regulates HIV-1 RNA stability and alternative splicing. Genes & Development. PMID 34140354 DOI: 10.1101/gad.348508.121  0.355
2020 Tsai K, Jaguva Vasudevan AA, Martinez Campos C, Emery A, Swanstrom R, Cullen BR. Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability. Cell Host & Microbe. PMID 32533923 DOI: 10.1016/J.Chom.2020.05.011  0.469
2020 Tsai K, Cullen BR. Epigenetic and epitranscriptomic regulation of viral replication. Nature Reviews. Microbiology. PMID 32533130 DOI: 10.1038/S41579-020-0382-3  0.439
2020 Irwan ID, Karnowski HL, Bogerd HP, Tsai K, Cullen BR. Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function. Mbio. 11. PMID 32487757 DOI: 10.1128/Mbio.01038-20  0.41
2020 Ganser LR, Chu CC, Bogerd HP, Kelly ML, Cullen BR, Al-Hashimi HM. Probing RNA Conformational Equilibria within the Functional Cellular Context. Cell Reports. 30: 2472-2480.e4. PMID 32101729 DOI: 10.1016/J.Celrep.2020.02.004  0.385
2019 Courtney DG, Tsai K, Bogerd HP, Kennedy EM, Law BA, Emery A, Swanstrom R, Holley CL, Cullen BR. Epitranscriptomic Addition of mC to HIV-1 Transcripts Regulates Viral Gene Expression. Cell Host & Microbe. 26: 217-227.e6. PMID 31415754 DOI: 10.1016/J.Chom.2019.07.005  0.744
2019 Courtney DG, Chalem A, Bogerd HP, Law BA, Kennedy EM, Holley CL, Cullen BR. Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression. Mbio. 10. PMID 31186331 DOI: 10.1128/Mbio.01209-19  0.748
2019 Cullen B, Roca X. Decision letter: Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing Elife. DOI: 10.7554/Elife.50530.033  0.432
2018 Tsai K, Courtney DG, Kennedy EM, Cullen BR. Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication. Rna (New York, N.Y.). PMID 29903832 DOI: 10.1261/Rna.066332.118  0.48
2018 Mefferd AL, Bogerd HP, Irwan ID, Cullen BR. Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas. Virology. 520: 116-126. PMID 29857168 DOI: 10.1016/J.Virol.2018.05.016  0.373
2018 Tsai K, Courtney DG, Cullen BR. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. Plos Pathogens. 14: e1006919. PMID 29447282 DOI: 10.1371/Journal.Ppat.1006919  0.449
2017 Heaton NS, Cullen BR. Viruses hijack a long non-coding RNA. Nature. 552: 184-185. PMID 32080446 DOI: 10.1038/D41586-017-07692-W  0.404
2017 Poling BC, Price AM, Luftig MA, Cullen BR. The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis. Virology. 512: 113-123. PMID 28950226 DOI: 10.1016/J.Virol.2017.09.015  0.416
2017 Courtney DG, Kennedy EM, Dumm RE, Bogerd HP, Tsai K, Heaton NS, Cullen BR. Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication. Cell Host & Microbe. 22: 377-386.e5. PMID 28910636 DOI: 10.1016/J.Chom.2017.08.004  0.41
2017 Cullen BR. RNA Interference in Mammals: The Virus Strikes Back. Immunity. 46: 970-972. PMID 28636964 DOI: 10.1016/J.Immuni.2017.05.004  0.444
2017 Poling BC, Tsai K, Kang D, Ren L, Kennedy EM, Cullen BR. A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs. Rna Biology. 0. PMID 28594311 DOI: 10.1080/15476286.2017.1334755  0.466
2017 Kennedy EM, Courtney DG, Tsai K, Cullen BR. Viral Epitranscriptomics. Journal of Virology. PMID 28250115 DOI: 10.1128/JVI.02263-16  0.334
2017 Bogerd HP, Kennedy EM, Whisnant AW, Cullen BR. Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity. Mbio. 8. PMID 28096489 DOI: 10.1128/Mbio.02125-16  0.82
2016 Kennedy EM, Kornepati AV, Bogerd HP, Cullen BR. Partial reconstitution of the RNAi response in human cells using Drosophila gene products. Rna (New York, N.Y.). PMID 27837013 DOI: 10.1261/Rna.059345.116  0.406
2016 Kennedy EM, Bogerd HP, Kornepati AV, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR. Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host & Microbe. PMID 27117054 DOI: 10.1016/J.Chom.2016.04.002  0.427
2015 Bogerd HP, Kornepati AV, Marshall JB, Kennedy EM, Cullen BR. Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators. Proceedings of the National Academy of Sciences of the United States of America. PMID 26668372 DOI: 10.1073/Pnas.1516305112  0.452
2015 Kennedy EM, Whisnant AW, Kornepati AV, Marshall JB, Bogerd HP, Cullen BR. Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621737 DOI: 10.1073/Pnas.1513421112  0.793
2015 Friedland AE, Baral R, Singhal P, Loveluck K, Shen S, Sanchez M, Marco E, Gotta GM, Maeder ML, Kennedy EM, Kornepati AV, Sousa A, Collins MA, Jayaram H, Cullen BR, et al. Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. Genome Biology. 16: 257. PMID 26596280 DOI: 10.1186/S13059-015-0817-8  0.315
2015 Kennedy EM, Kornepati AV, Cullen BR. Targeting hepatitis B virus cccDNA using CRISPR/Cas9. Antiviral Research. 123: 188-92. PMID 26476375 DOI: 10.1016/J.Antiviral.2015.10.004  0.363
2015 Skalsky RL, Cullen BR. EBV Noncoding RNAs. Current Topics in Microbiology and Immunology. 391: 181-217. PMID 26428375 DOI: 10.1007/978-3-319-22834-1_6  0.548
2015 Gregorovic G, Boulden EA, Bosshard R, Elgueta Karstegl C, Skalsky R, Cullen BR, Gujer C, Rämer P, Münz C, Farrell PJ. Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice. Journal of Virology. 89: 11711-4. PMID 26339045 DOI: 10.1128/Jvi.01873-15  0.508
2015 Kennedy EM, Kornepati AV, Mefferd AL, Marshall JB, Tsai K, Bogerd HP, Cullen BR. Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic. Methods (San Diego, Calif.). PMID 26291065 DOI: 10.1016/J.Ymeth.2015.08.012  0.345
2015 Mefferd AL, Kornepati AV, Bogerd HP, Kennedy EM, Cullen BR. Expression of CRISPR/Cas single guide RNAs using small tRNA promoters. Rna (New York, N.Y.). 21: 1683-9. PMID 26187160 DOI: 10.1261/Rna.051631.115  0.4
2015 Kang D, Skalsky RL, Cullen BR. EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. Plos Pathogens. 11: e1004979. PMID 26070070 DOI: 10.1371/Journal.Ppat.1004979  0.437
2015 Cullen BR. The virology-RNA biology connection. Rna (New York, N.Y.). 21: 592-4. PMID 25780153 DOI: 10.1261/Rna.049882.115  0.337
2015 Kennedy EM, Cullen BR. Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment. Virology. 479: 213-20. PMID 25759096 DOI: 10.1016/J.Virol.2015.02.024  0.385
2015 Kennedy EM, Bassit LC, Mueller H, Kornepati AV, Bogerd HP, Nie T, Chatterjee P, Javanbakht H, Schinazi RF, Cullen BR. Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. Virology. 476: 196-205. PMID 25553515 DOI: 10.1016/J.Virol.2014.12.001  0.35
2014 Cullen BR. HIV-1 Packing to Leave. Cell. 159: 975-6. PMID 25416937 DOI: 10.1016/J.Cell.2014.11.008  0.399
2014 Cullen BR. Viruses and RNA interference: issues and controversies. Journal of Virology. 88: 12934-6. PMID 25210170 DOI: 10.1128/Jvi.01179-14  0.363
2014 Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR. Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. Plos One. 9: e106434. PMID 25184567 DOI: 10.1371/Journal.Pone.0106434  0.483
2014 Kennedy EM, Kornepati AV, Goldstein M, Bogerd HP, Poling BC, Whisnant AW, Kastan MB, Cullen BR. Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease. Journal of Virology. 88: 11965-72. PMID 25100830 DOI: 10.1128/Jvi.01879-14  0.73
2014 Skalsky RL, Olson KE, Blair CD, Garcia-Blanco MA, Cullen BR. A "microRNA-like" small RNA expressed by Dengue virus? Proceedings of the National Academy of Sciences of the United States of America. 111: E2359. PMID 24853506 DOI: 10.1073/Pnas.1406854111  0.508
2014 Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR. Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs. Journal of Virology. 88: 8065-76. PMID 24807715 DOI: 10.1128/Jvi.00985-14  0.819
2014 Bogerd HP, Whisnant AW, Kennedy EM, Flores O, Cullen BR. Derivation and characterization of Dicer- and microRNA-deficient human cells. Rna (New York, N.Y.). 20: 923-37. PMID 24757167 DOI: 10.1261/Rna.044545.114  0.8
2014 Furuse Y, Dastjerdi A, Seilern-Moy K, Steinbach F, Cullen BR. Analysis of viral microRNA expression by elephant endotheliotropic herpesvirus 1. Virology. 454: 102-8. PMID 24725936 DOI: 10.1016/J.Virol.2014.02.009  0.476
2014 Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM. A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host & Microbe. 15: 446-56. PMID 24721573 DOI: 10.1016/J.Chom.2014.03.004  0.803
2014 Whisnant AW, Kehl T, Bao Q, Materniak M, Kuzmak J, Löchelt M, Cullen BR. Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus. Journal of Virology. 88: 4679-86. PMID 24522910 DOI: 10.1128/Jvi.03587-13  0.81
2014 Flores O, Kennedy EM, Skalsky RL, Cullen BR. Differential RISC association of endogenous human microRNAs predicts their inhibitory potential. Nucleic Acids Research. 42: 4629-39. PMID 24464996 DOI: 10.1093/Nar/Gkt1393  0.467
2014 Parnas O, Corcoran DL, Cullen BR. Analysis of the mRNA targetome of microRNAs expressed by Marek's disease virus. Mbio. 5: e01060-13. PMID 24449754 DOI: 10.1128/Mbio.01060-13  0.471
2014 Skalsky RL, Kang D, Linnstaedt SD, Cullen BR. Evolutionary conservation of primate lymphocryptovirus microRNA targets. Journal of Virology. 88: 1617-35. PMID 24257599 DOI: 10.1128/Jvi.02071-13  0.506
2014 Cullen BR. Interview with Bryan R Cullen Future Virology. 9: 345-350. DOI: 10.2217/Fvl.14.17  0.418
2013 Cullen BR. How do viruses avoid inhibition by endogenous cellular microRNAs? Plos Pathogens. 9: e1003694. PMID 24244153 DOI: 10.1371/Journal.Ppat.1003694  0.499
2013 Furuse Y, Ornelles DA, Cullen BR. Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA. Virology. 447: 140-5. PMID 24210108 DOI: 10.1016/J.Virol.2013.08.024  0.514
2013 Cullen BR, Cherry S, tenOever BR. Is RNA interference a physiologically relevant innate antiviral immune response in mammals? Cell Host & Microbe. 14: 374-8. PMID 24139396 DOI: 10.1016/J.Chom.2013.09.011  0.356
2013 Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, Shepherd J, Kang SG, Liu WH, Sabouri-Ghomi M, Cullen BR, Rajewsky K, Xiao C. MicroRNA-17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways Embo Journal. 32: 2377-2391. PMID 23921550 DOI: 10.1038/Emboj.2013.178  0.384
2013 Majoros WH, Lekprasert P, Mukherjee N, Skalsky RL, Corcoran DL, Cullen BR, Ohler U. MicroRNA target site identification by integrating sequence and binding information. Nature Methods. 10: 630-3. PMID 23708386 DOI: 10.1038/Nmeth.2489  0.415
2013 Whisnant AW, Bogerd HP, Flores O, Ho P, Powers JG, Sharova N, Stevenson M, Chen CH, Cullen BR. In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. Mbio. 4: e000193. PMID 23592263 DOI: 10.1128/Mbio.00193-13  0.816
2013 Flores O, Nakayama S, Whisnant AW, Javanbakht H, Cullen BR, Bloom DC. Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. Journal of Virology. 87: 6589-603. PMID 23536669 DOI: 10.1128/Jvi.00504-13  0.8
2013 Cullen BR. Making a NeST for a persistent virus. Cell Host & Microbe. 13: 241-2. PMID 23498947 DOI: 10.1016/J.Chom.2013.02.016  0.39
2013 Wahl A, Linnstaedt SD, Esoda C, Krisko JF, Martinez-Torres F, Delecluse HJ, Cullen BR, Garcia JV. A cluster of virus-encoded microRNAs accelerates acute systemic Epstein-Barr virus infection but does not significantly enhance virus-induced oncogenesis in vivo. Journal of Virology. 87: 5437-46. PMID 23468485 DOI: 10.1128/Jvi.00281-13  0.488
2013 Cullen BR. MicroRNAs as mediators of viral evasion of the immune system. Nature Immunology. 14: 205-10. PMID 23416678 DOI: 10.1038/Ni.2537  0.48
2012 Cullen BR. MicroRNA expression by an oncogenic retrovirus. Proceedings of the National Academy of Sciences of the United States of America. 109: 2695-6. PMID 22308505 DOI: 10.1073/Pnas.1200328109  0.52
2012 Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler U, Cullen BR. The viral and cellular microRNA targetome in lymphoblastoid cell lines. Plos Pathogens. 8: e1002484. PMID 22291592 DOI: 10.1371/Journal.Ppat.1002484  0.499
2012 Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Hafner M, Nusbaum JD, Feederle R, Delecluse H, Luftig M, Tuschl T, Ohler U, Cullen BR. Analysis of the miRNA targetome in EBV-infected B cells Infectious Agents and Cancer. 7. DOI: 10.1186/1750-9378-7-S1-O2  0.495
2011 Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD, Shamulailatpam P, Love CL, Dave SS, Tuschl T, Ohler U, Cullen BR. Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host & Microbe. 10: 515-26. PMID 22100165 DOI: 10.1016/J.Chom.2011.09.012  0.493
2011 Zhang A, Bogerd H, Villinger F, Das Gupta J, Dong B, Klein EA, Hackett J, Schochetman G, Cullen BR, Silverman RH. In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins. Virology. 421: 28-33. PMID 21982221 DOI: 10.1016/J.Virol.2011.08.030  0.383
2011 Cullen BR. Herpesvirus microRNAs: phenotypes and functions. Current Opinion in Virology. 1: 211-5. PMID 21927637 DOI: 10.1016/J.Coviro.2011.04.003  0.518
2011 Skalsky RL, Cullen BR. Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. Plos One. 6: e24248. PMID 21912681 DOI: 10.1371/Journal.Pone.0024248  0.443
2011 Cullen BR. Viruses and microRNAs: RISCy interactions with serious consequences. Genes & Development. 25: 1881-94. PMID 21896651 DOI: 10.1101/Gad.17352611  0.52
2011 Feederle R, Haar J, Bernhardt K, Linnstaedt SD, Bannert H, Lips H, Cullen BR, Delecluse HJ. The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes. Journal of Virology. 85: 9801-10. PMID 21752900 DOI: 10.1128/Jvi.05100-11  0.424
2011 Feederle R, Linnstaedt SD, Bannert H, Lips H, Bencun M, Cullen BR, Delecluse HJ. A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus. Plos Pathogens. 7: e1001294. PMID 21379335 DOI: 10.1371/Journal.Ppat.1001294  0.496
2011 Bogerd HP, Zhang F, Bieniasz PD, Cullen BR. Human APOBEC3 proteins can inhibit xenotropic murine leukemia virus-related virus infectivity. Virology. 410: 234-9. PMID 21131013 DOI: 10.1016/J.Virol.2010.11.011  0.398
2011 Cullen BR. RNA interference does not function as an innate antiviral response in mammalian somatic cells Future Virology. 6: 1381-1384. DOI: 10.2217/Fvl.11.112  0.373
2010 Linnstaedt SD, Gottwein E, Skalsky RL, Luftig MA, Cullen BR. Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus. Journal of Virology. 84: 11670-8. PMID 20844043 DOI: 10.1128/Jvi.01248-10  0.402
2010 Umbach JL, Yen HL, Poon LL, Cullen BR. Influenza A virus expresses high levels of an unusual class of small viral leader RNAs in infected cells. Mbio. 1. PMID 20842206 DOI: 10.1128/Mbio.00204-10  0.819
2010 Umbach JL, Strelow LI, Wong SW, Cullen BR. Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques. Virology. 405: 592-9. PMID 20655562 DOI: 10.1016/J.Virol.2010.06.036  0.822
2010 Skalsky RL, Cullen BR. Viruses, microRNAs, and host interactions. Annual Review of Microbiology. 64: 123-41. PMID 20477536 DOI: 10.1146/Annurev.Micro.112408.134243  0.507
2010 Kelly EJ, Hadac EM, Cullen BR, Russell SJ. MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference. Plos Pathogens. 6: e1000820. PMID 20333250 DOI: 10.1371/Journal.Ppat.1000820  0.464
2010 Gottwein E, Cullen BR. A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest. Journal of Virology. 84: 5229-37. PMID 20219912 DOI: 10.1128/Jvi.00202-10  0.42
2010 Cullen BR. Five questions about viruses and microRNAs. Plos Pathogens. 6: e1000787. PMID 20195463 DOI: 10.1371/Journal.Ppat.1000787  0.479
2010 Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR. Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus. Bmc Genomics. 11: 119. PMID 20167119 DOI: 10.1186/1471-2164-11-119  0.505
2010 Bogerd HP, Karnowski HW, Cai X, Shin J, Pohlers M, Cullen BR. A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs. Molecular Cell. 37: 135-42. PMID 20129062 DOI: 10.1016/J.Molcel.2009.12.016  0.464
2010 Umbach JL, Wang K, Tang S, Krause PR, Mont EK, Cohen JI, Cullen BR. Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2. Journal of Virology. 84: 1189-92. PMID 19889786 DOI: 10.1128/Jvi.01712-09  0.814
2010 Umbach JL, Cullen BR. In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. Journal of Virology. 84: 695-703. PMID 19889781 DOI: 10.1128/Jvi.02013-09  0.809
2010 Linnstaedt S, Gottwein E, Luftig M, Cullen B. Epstein-Barr virus (EBV)-associated miRNAs are important for the maintenance of EBV transformed B cells Infectious Agents and Cancer. 5. DOI: 10.1186/1750-9378-5-S1-A28  0.466
2010 Forte E, Chang C, Tourigny J, Gottwein E, Cullen B, Dave S, Luftig M. EBV-induced miR-34a functions to stimulate transformed B cell growth Infectious Agents and Cancer. 5. DOI: 10.1186/1750-9378-5-S1-A23  0.463
2009 Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR. Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. Journal of Virology. 83: 10677-83. PMID 19656888 DOI: 10.1128/Jvi.01185-09  0.822
2009 Umbach JL, Cullen BR. The role of RNAi and microRNAs in animal virus replication and antiviral immunity. Genes & Development. 23: 1151-64. PMID 19451215 DOI: 10.1101/Gad.1793309  0.808
2009 Cullen BR. Viral RNAs: lessons from the enemy. Cell. 136: 592-7. PMID 19239880 DOI: 10.1016/J.Cell.2009.01.048  0.464
2009 Cullen BR. Viral and cellular messenger RNA targets of viral microRNAs. Nature. 457: 421-5. PMID 19158788 DOI: 10.1038/Nature07757  0.468
2009 Sullivan CS, Cullen BR. Non-coding regulatory RNAs of the DNA tumor viruses Dna Tumor Viruses. 645-682. DOI: 10.1007/978-0-387-68945-6_25  0.51
2008 Bogerd HP, Tallmadge RL, Oaks JL, Carpenter S, Cullen BR. Equine infectious anemia virus resists the antiretroviral activity of equine APOBEC3 proteins through a packaging-independent mechanism. Journal of Virology. 82: 11889-901. PMID 18818324 DOI: 10.1128/Jvi.01537-08  0.431
2008 Gooch BD, Cullen BR. Functional domain organization of human APOBEC3G. Virology. 379: 118-24. PMID 18639915 DOI: 10.1016/J.Virol.2008.06.013  0.383
2008 Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR. MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature. 454: 780-3. PMID 18596690 DOI: 10.1038/Nature07103  0.837
2008 Gottwein E, Cullen BR. Viral and cellular microRNAs as determinants of viral pathogenesis and immunity. Cell Host & Microbe. 3: 375-87. PMID 18541214 DOI: 10.1016/J.Chom.2008.05.002  0.501
2008 Bogerd HP, Cullen BR. Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation. Rna (New York, N.Y.). 14: 1228-36. PMID 18456846 DOI: 10.1261/Rna.964708  0.408
2007 Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, Chi JT, Braich R, Manoharan M, Soutschek J, Ohler U, Cullen BR. A viral microRNA functions as an orthologue of cellular miR-155. Nature. 450: 1096-9. PMID 18075594 DOI: 10.1038/Nature05992  0.481
2007 Wiegand HL, Cullen BR. Inhibition of alpharetrovirus replication by a range of human APOBEC3 proteins. Journal of Virology. 81: 13694-9. PMID 17913830 DOI: 10.1128/Jvi.01646-07  0.372
2007 Lin J, Cullen BR. Analysis of the interaction of primate retroviruses with the human RNA interference machinery. Journal of Virology. 81: 12218-26. PMID 17855543 DOI: 10.1128/Jvi.01390-07  0.508
2007 Gottwein E, Cullen BR. Protocols for expression and functional analysis of viral microRNAs. Methods in Enzymology. 427: 229-43. PMID 17720488 DOI: 10.1016/S0076-6879(07)27013-2  0.515
2007 Cullen BR. Immunology. Outwitted by viral RNAs. Science (New York, N.Y.). 317: 329-30. PMID 17641188 DOI: 10.1126/Science.1146077  0.426
2007 Schäfer A, Cai X, Bilello JP, Desrosiers RC, Cullen BR. Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. Virology. 364: 21-7. PMID 17451774 DOI: 10.1016/J.Virol.2007.03.029  0.507
2007 Bogerd HP, Wiegand HL, Doehle BP, Cullen BR. The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains. Virology. 364: 486-93. PMID 17434555 DOI: 10.1016/J.Virol.2007.03.019  0.71
2007 Cai X, Cullen BR. The imprinted H19 noncoding RNA is a primary microRNA precursor. Rna (New York, N.Y.). 13: 313-6. PMID 17237358 DOI: 10.1261/Rna.351707  0.398
2007 Hulme AE, Bogerd HP, Cullen BR, Moran JV. Selective inhibition of Alu retrotransposition by APOBEC3G. Gene. 390: 199-205. PMID 17079095 DOI: 10.1016/J.Gene.2006.08.032  0.34
2006 Gottwein E, Cai X, Cullen BR. Expression and function of microRNAs encoded by kaposi's sarcoma-associated herpesvirus Cold Spring Harbor Symposia On Quantitative Biology. 71: 357-364. PMID 17381317 DOI: 10.1101/Sqb.2006.71.004  0.488
2006 Cai X, Li G, Laimins LA, Cullen BR. Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. Journal of Virology. 80: 10890-3. PMID 17041229 DOI: 10.1128/Jvi.01175-06  0.446
2006 Doehle BP, Bogerd HP, Wiegand HL, Jouvenet N, Bieniasz PD, Hunter E, Cullen BR. The betaretrovirus Mason-Pfizer monkey virus selectively excludes simian APOBEC3G from virion particles. Journal of Virology. 80: 12102-8. PMID 17035335 DOI: 10.1128/Jvi.01600-06  0.693
2006 Zeng Y, Cullen BR. Recognition and cleavage of primary microRNA transcripts. Methods in Molecular Biology (Clifton, N.J.). 342: 49-56. PMID 16957366 DOI: 10.1385/1-59745-123-1:49  0.46
2006 Cullen BR. Viruses and microRNAs. Nature Genetics. 38: S25-30. PMID 16736021 DOI: 10.1038/Ng1793  0.51
2006 Cullen BR. Is RNA interference involved in intrinsic antiviral immunity in mammals? Nature Immunology. 7: 563-7. PMID 16715068 DOI: 10.1038/Ni1352  0.362
2006 Gottwein E, Cai X, Cullen BR. A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing. Journal of Virology. 80: 5321-6. PMID 16699012 DOI: 10.1128/Jvi.02734-05  0.5
2006 Cai X, Schäfer A, Lu S, Bilello JP, Desrosiers RC, Edwards R, Raab-Traub N, Cullen BR. Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. Plos Pathogens. 2: e23. PMID 16557291 DOI: 10.1371/Journal.Ppat.0020023  0.677
2006 Cai X, Cullen BR. Transcriptional origin of Kaposi's sarcoma-associated herpesvirus microRNAs. Journal of Virology. 80: 2234-42. PMID 16474131 DOI: 10.1128/Jvi.80.5.2234-2242.2006  0.454
2006 Wäldele K, Silbermann K, Schneider G, Ruckes T, Cullen BR, Grassmann R. Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes. Blood. 107: 4491-9. PMID 16467195 DOI: 10.1182/Blood-2005-08-3138  0.37
2006 Bogerd HP, Wiegand HL, Doehle BP, Lueders KK, Cullen BR. APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells. Nucleic Acids Research. 34: 89-95. PMID 16407327 DOI: 10.1093/Nar/Gkj416  0.704
2006 Cullen BR. Induction of stable RNA interference in mammalian cells. Gene Therapy. 13: 503-8. PMID 16195700 DOI: 10.1038/Sj.Gt.3302656  0.366
2005 Cullen BR. RNAi the natural way. Nature Genetics. 37: 1163-5. PMID 16254559 DOI: 10.1038/Ng1105-1163  0.355
2005 Heitman J, Cullen BR. Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel? Molecular Cell. 19: 145-6. PMID 16039584 DOI: 10.1016/J.Molcel.2005.07.001  0.364
2005 Russell RA, Wiegand HL, Moore MD, Schäfer A, McClure MO, Cullen BR. Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors. Journal of Virology. 79: 8724-31. PMID 15994766 DOI: 10.1128/Jvi.79.14.8724-8731.2005  0.439
2005 Doehle BP, Schäfer A, Cullen BR. Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif. Virology. 339: 281-8. PMID 15993456 DOI: 10.1016/J.Virol.2005.06.005  0.703
2005 Doehle BP, Schäfer A, Wiegand HL, Bogerd HP, Cullen BR. Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion. Journal of Virology. 79: 8201-7. PMID 15956565 DOI: 10.1128/Jvi.79.13.8201-8207.2005  0.715
2005 Zeng Y, Cullen BR. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. The Journal of Biological Chemistry. 280: 27595-603. PMID 15932881 DOI: 10.1074/Jbc.M504714200  0.471
2005 Cullen BR. Does RNA interference have a future as a treatment for HIV-1 induced disease? Aids Reviews. 7: 22-5. PMID 15875658  0.35
2005 Dutko JA, Schäfer A, Kenny AE, Cullen BR, Curcio MJ. Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases. Current Biology : Cb. 15: 661-6. PMID 15823539 DOI: 10.1016/J.Cub.2005.02.051  0.441
2005 Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 5570-5. PMID 15800047 DOI: 10.1073/Pnas.0408192102  0.701
2005 Moore MD, McGarvey MJ, Russell RA, Cullen BR, McClure MO. Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors. The Journal of Gene Medicine. 7: 918-25. PMID 15756649 DOI: 10.1002/Jgm.739  0.441
2005 Zeng Y, Cai X, Cullen BR. Use of RNA polymerase II to transcribe artificial microRNAs. Methods in Enzymology. 392: 371-80. PMID 15644193 DOI: 10.1016/S0076-6879(04)92022-8  0.492
2005 Cullen BR. Human immunodeficiency virus: nuclear RNA export unwound. Nature. 433: 26-7. PMID 15635396 DOI: 10.1038/433026A  0.429
2005 Yi R, Doehle BP, Qin Y, Macara IG, Cullen BR. Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. Rna (New York, N.Y.). 11: 220-6. PMID 15613540 DOI: 10.1261/Rna.7233305  0.8
2005 Zeng Y, Yi R, Cullen BR. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. The Embo Journal. 24: 138-48. PMID 15565168 DOI: 10.1038/Sj.Emboj.7600491  0.614
2004 Lu S, Cullen BR. Nonsense mediated decay induced by tethered human UPF3B is restricted to the cytoplasm. Rna Biology. 1: 42-7. PMID 17194930 DOI: 10.4161/Rna.1.1.916  0.61
2004 Cullen BR. Transcription and processing of human microRNA precursors. Molecular Cell. 16: 861-5. PMID 15610730 DOI: 10.1016/J.Molcel.2004.12.002  0.415
2004 Lu S, Cullen BR. Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis. Journal of Virology. 78: 12868-76. PMID 15542639 DOI: 10.1128/Jvi.78.23.12868-12876.2004  0.667
2004 Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. Rna (New York, N.Y.). 10: 1957-66. PMID 15525708 DOI: 10.1261/Rna.7135204  0.477
2004 Schäfer A, Bogerd HP, Cullen BR. Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor. Virology. 328: 163-8. PMID 15464836 DOI: 10.1016/J.Virol.2004.08.006  0.439
2004 Zeng Y, Cullen BR. Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Research. 32: 4776-85. PMID 15356295 DOI: 10.1093/Nar/Gkh824  0.442
2004 Wiegand HL, Doehle BP, Bogerd HP, Cullen BR. A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins. The Embo Journal. 23: 2451-8. PMID 15152192 DOI: 10.1038/Sj.Emboj.7600246  0.71
2004 Cullen BR. Derivation and function of small interfering RNAs and microRNAs. Virus Research. 102: 3-9. PMID 15068874 DOI: 10.1016/J.Virusres.2004.01.009  0.508
2004 Bogerd HP, Doehle BP, Wiegand HL, Cullen BR. A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor. Proceedings of the National Academy of Sciences of the United States of America. 101: 3770-4. PMID 14999100 DOI: 10.1073/Pnas.0307713101  0.71
2004 Cullen BR. Assaying nuclear messenger RNA export in human cells. Methods in Molecular Biology (Clifton, N.J.). 257: 85-92. PMID 14769998 DOI: 10.1385/1-59259-750-5:085  0.414
2003 Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Development. 17: 3011-6. PMID 14681208 DOI: 10.1101/Gad.1158803  0.662
2003 Lee MT, Coburn GA, McClure MO, Cullen BR. Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector. Journal of Virology. 77: 11964-72. PMID 14581533 DOI: 10.1128/Jvi.77.22.11964-11972.2003  0.499
2003 Wiegand HL, Lu S, Cullen BR. Exon junction complexes mediate the enhancing effect of splicing on mRNA expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 11327-32. PMID 12972633 DOI: 10.1073/Pnas.1934877100  0.611
2003 Cullen BR. HIV-1 infection: fooling the gatekeeper. Nature Medicine. 9: 1112-3. PMID 12949520 DOI: 10.1038/Nm0903-1112  0.396
2003 Cullen BR. Nuclear mRNA export: insights from virology. Trends in Biochemical Sciences. 28: 419-24. PMID 12932730 DOI: 10.1016/S0968-0004(03)00142-7  0.435
2003 Zeng Y, Yi R, Cullen BR. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 100: 9779-84. PMID 12902540 DOI: 10.1073/Pnas.1630797100  0.667
2003 Shoya Y, Tokunaga K, Sawa H, Maeda M, Ueno T, Yoshikawa T, Hasegawa H, Sata T, Kurata T, Hall WW, Cullen BR, Takahashi H. Human topoisomerase I promotes HIV-1 proviral DNA synthesis: implications for the species specificity and cellular tropism of HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 100: 8442-7. PMID 12829794 DOI: 10.1073/Pnas.1430827100  0.393
2003 Lu S, Cullen BR. Analysis of the stimulatory effect of splicing on mRNA production and utilization in mammalian cells. Rna (New York, N.Y.). 9: 618-30. PMID 12702820 DOI: 10.1261/Rna.5260303  0.6
2003 Coburn GA, Cullen BR. siRNAs: a new wave of RNA-based therapeutics. The Journal of Antimicrobial Chemotherapy. 51: 753-6. PMID 12654731 DOI: 10.1093/Jac/Dkg166  0.386
2003 Zeng Y, Cullen BR. Sequence requirements for micro RNA processing and function in human cells. Rna (New York, N.Y.). 9: 112-23. PMID 12554881 DOI: 10.1261/Rna.2780503  0.466
2003 Cullen BR. Nuclear RNA export. Journal of Cell Science. 116: 587-97. PMID 12538759 DOI: 10.1242/Jcs.00268  0.377
2002 Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. Journal of Virology. 76: 9225-31. PMID 12186906 DOI: 10.1128/Jvi.76.18.9225-9231.2002  0.506
2002 Zeng Y, Cullen BR. RNA interference in human cells is restricted to the cytoplasm. Rna (New York, N.Y.). 8: 855-60. PMID 12166640 DOI: 10.1017/S1355838202020071  0.387
2002 Cullen BR. RNA interference: antiviral defense and genetic tool. Nature Immunology. 3: 597-9. PMID 12087412 DOI: 10.1038/Ni0702-597  0.39
2002 Zeng Y, Wagner EJ, Cullen BR. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Molecular Cell. 9: 1327-33. PMID 12086629 DOI: 10.1016/S1097-2765(02)00541-5  0.504
2002 Yi R, Bogerd HP, Wiegand HL, Cullen BR. Both ran and importins have the ability to function as nuclear mRNA export factors. Rna (New York, N.Y.). 8: 180-7. PMID 11911364 DOI: 10.1017/S1355838202012384  0.573
2002 Ho DN, Coburn GA, Kang Y, Cullen BR, Georgiadis MM. The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proceedings of the National Academy of Sciences of the United States of America. 99: 1888-93. PMID 11854490 DOI: 10.1073/Pnas.042698599  0.536
2002 Yi R, Bogerd HP, Cullen BR. Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. Journal of Virology. 76: 2036-42. PMID 11836381 DOI: 10.1128/Jvi.76.5.2036-2042.2002  0.667
2002 Cullen BR. Using retroviruses to study the nuclear export of mRNA. Results and Problems in Cell Differentiation. 35: 151-68. PMID 11791405 DOI: 10.1007/978-3-540-44603-3_8  0.303
2002 Wiegand HL, Coburn GA, Zeng Y, Kang Y, Bogerd HP, Cullen BR. Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. Molecular and Cellular Biology. 22: 245-56. PMID 11739738 DOI: 10.1128/Mcb.22.1.245-256.2002  0.578
2001 Yang J, Bogerd HP, Wang PJ, Page DC, Cullen BR. Two closely related human nuclear export factors utilize entirely distinct export pathways. Molecular Cell. 8: 397-406. PMID 11545741 DOI: 10.1016/S1097-2765(01)00303-3  0.4
2001 Cullen BR. Journey to the center of the cell Cell. 105: 697-700. PMID 11440710 DOI: 10.1016/S0092-8674(01)00392-0  0.39
2001 Russell RA, Zeng Y, Erlwein O, Cullen BR, McClure MO. The R region found in the human foamy virus long terminal repeat is critical for both Gag and Pol protein expression. Journal of Virology. 75: 6817-24. PMID 11435560 DOI: 10.1128/Jvi.75.15.6817-6824.2001  0.367
2001 Tokunaga K, Greenberg ML, Morse MA, Cumming RI, Lyerly HK, Cullen BR. Molecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolates Journal of Virology. 75: 6776-6785. PMID 11435556 DOI: 10.1128/Jvi.75.15.6776-6785.2001  0.379
2001 Coburn GA, Wiegand HL, Kang Y, Ho DN, Georgiadis MM, Cullen BR. Using viral species specificity to define a critical protein/RNA interaction surface. Genes & Development. 15: 1194-205. PMID 11358864 DOI: 10.1101/Gad.888201  0.573
2001 Cullen BR. A new entry route for HIV Nature Medicine. 7: 20-21. PMID 11135605 DOI: 10.1038/83295  0.331
2000 Yang J, Bogerd H, Le SY, Cullen BR. The human endogenous retrovirus K Rev response element coincides with a predicted RNA folding region. Rna (New York, N.Y.). 6: 1551-64. PMID 11105755 DOI: 10.1017/S135583820000100X  0.311
2000 Cullen BR. Principles and applications of a tat-based assay for analyzing specific RNA-protein interactions in mammalian cells Methods in Enzymology. 328: 322-329. PMID 11075353 DOI: 10.1016/S0076-6879(00)28405-X  0.485
2000 Cullen BR. Utility of the secreted placental alkaline phosphatase reporter enzyme Methods in Enzymology. 326: 159-164. PMID 11036641 DOI: 10.1016/S0076-6879(00)26053-9  0.32
2000 Neufeld KL, Nix DA, Bogerd H, Kang Y, Beckerle MC, Cullen BR, White RL. Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 97: 12085-90. PMID 11035805 DOI: 10.1073/Pnas.220401797  0.517
2000 Bieniasz PD, Cullen BR. Multiple blocks to human immunodeficiency virus type 1 replication in rodent cells Journal of Virology. 74: 9868-9877. PMID 11024113 DOI: 10.1128/Jvi.74.21.9868-9877.2000  0.431
2000 Bogerd HP, Wlegand HL, Yang J, Cullen BR. Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K Journal of Virology. 74: 9353-9361. PMID 11000203 DOI: 10.1128/Jvi.74.20.9353-9361.2000  0.41
2000 Kang Y, Bogerd HP, Cullen BR. Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. Journal of Virology. 74: 5863-71. PMID 10846066 DOI: 10.1128/Jvi.74.13.5863-5871.2000  0.582
2000 Cullen BR. Nuclear RNA export pathways Molecular and Cellular Biology. 20: 4181-4187. PMID 10825183 DOI: 10.1128/Mcb.20.12.4181-4187.2000  0.387
2000 Bogerd HP, Wiegand HL, Bieniasz PD, Cullen BR. Functional differences between human and bovine immunodeficiency virus Tat transcription factors. Journal of Virology. 74: 4666-71. PMID 10775603 DOI: 10.1128/Jvi.74.10.4666-4671.2000  0.439
2000 Cullen BR. Connections between the processing and nuclear export of mRNA: Evidence for an export license? Proceedings of the National Academy of Sciences of the United States of America. 97: 4-6. PMID 10618360 DOI: 10.1073/Pnas.97.1.4  0.373
1999 Yang J, Cullen BR. Structural and functional analysis of the avian leukemia virus constitutive transport element Rna. 5: 1645-1655. PMID 10606274 DOI: 10.1017/S1355838299991616  0.421
1999 Yang J, Bogerd HP, Peng S, Wiegand H, Truant R, Cullen BR. An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 13404-8. PMID 10557333 DOI: 10.1073/Pnas.96.23.13404  0.405
1999 Truant R, Kang Y, Cullen BR. The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function. The Journal of Biological Chemistry. 274: 32167-71. PMID 10542253 DOI: 10.1074/Jbc.274.45.32167  0.522
1999 Kang Y, Bogerd HP, Yang J, Cullen BR. Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor. Virology. 262: 200-9. PMID 10489353 DOI: 10.1006/Viro.1999.9906  0.585
1999 Cullen BR. HIV-1 Nef protein: An invitation to a kill Nature Medicine. 5: 985-986. PMID 10470067 DOI: 10.1038/12417  0.325
1999 Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR. Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription. Proceedings of the National Academy of Sciences of the United States of America. 96: 7791-6. PMID 10393900 DOI: 10.1073/Pnas.96.14.7791  0.407
1999 Ross TM, Bieniasz PD, Cullen BR. Role of chemokine receptors in HIV-1 infection and pathogenesis Advances in Virus Research. 52: 233-267. PMID 10384237 DOI: 10.1016/S0065-3527(08)60300-0  0.379
1999 Ross TM, Oran AE, Cullen BR. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein Current Biology. 9: 613-621. PMID 10375525 DOI: 10.1016/S0960-9822(99)80283-8  0.343
1999 Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR. Highly divergent lentiviral Tat proteins activate viral gene expression by a common mechanism. Molecular and Cellular Biology. 19: 4592-9. PMID 10373508 DOI: 10.1128/Mcb.19.7.4592  0.476
1999 Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR. Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes. Journal of Virology. 73: 5777-86. PMID 10364329 DOI: 10.1128/Jvi.73.7.5777-5786.1999  0.457
1999 Kang Y, Cullen BR. The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes & Development. 13: 1126-39. PMID 10323864 DOI: 10.1101/Gad.13.9.1126  0.597
1999 Truant R, Cullen BR. The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin β-dependent nuclear localization signals Molecular and Cellular Biology. 19: 1210-1217. PMID 9891055 DOI: 10.1128/Mcb.19.2.1210  0.306
1999 Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR. Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat. The Embo Journal. 17: 7056-65. PMID 9843510 DOI: 10.1093/Emboj/17.23.7056  0.388
1998 Truant R, Fridell RA, Benson ER, Herold A, Cullen BR. Nucleocytoplasmic shuttling by protein nuclear import factors. European Journal of Cell Biology. 77: 269-75. PMID 9930651 DOI: 10.1016/S0171-9335(98)80085-X  0.326
1998 Cullen BR. Retroviruses as model systems for the study of nuclear RNA export pathways Virology. 249: 203-210. PMID 9791012 DOI: 10.1006/Viro.1998.9331  0.323
1998 Bogerd HP, Echarri A, Ross TM, Cullen BR. Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1 Journal of Virology. 72: 8627-8635. PMID 9765402 DOI: 10.1128/Jvi.72.11.8627-8635.1998  0.498
1998 Ross TM, Cullen BR. The ability of HIV type 1 to use CCR-3 as a coreceptor is controlled by envelope V1/V2 sequences acting in conjunction with a CCR-5 tropic V3 loop Proceedings of the National Academy of Sciences of the United States of America. 95: 7682-7686. PMID 9636210 DOI: 10.1073/Pnas.95.13.7682  0.324
1998 Cullen BR. HIV-1 auxiliary proteins: Making connections in a dying cell Cell. 93: 685-692. PMID 9630214 DOI: 10.1016/S0092-8674(00)81431-2  0.375
1998 Kang Y, Cullen BR. Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. Journal of Virology. 72: 5502-9. PMID 9621006 DOI: 10.1128/Jvi.72.7.5502-5509.1998  0.518
1998 Ross TM, Bieniasz PD, Cullen BR. Multiple residues contribute to the inability of murine CCR-5 to function as a coreceptor for macrophage-tropic human immunodeficiency virus type 1 isolates Journal of Virology. 72: 1918-1924. PMID 9499044 DOI: 10.1128/Jvi.72.3.1918-1924.1998  0.388
1998 Truant R, Fridell RA, Benson RE, Bogerd H, Cullen BR. Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Molecular and Cellular Biology. 18: 1449-58. PMID 9488461 DOI: 10.1128/Mcb.18.3.1449  0.311
1998 Kang Y, Blair WS, Cullen BR. Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter. Journal of Virology. 72: 504-11. PMID 9420252 DOI: 10.1128/Jvi.72.1.504-511.1998  0.555
1998 Bogerd HP, Echarri A, Ross TM, Cullen BR. Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1 Journal of Virology. 72: 8627-8635. DOI: 10.1128/jvi.72.11.8627-8635.1998  0.4
1998 Cullen BR. Posttranscriptional regulation by the HIV-1 rev protein Seminars in Virology. 8: 327-334. DOI: 10.1006/Smvy.1997.0135  0.466
1997 Aramori I, Ferguson SS, Bieniasz PD, Zhang J, Cullen B, Cullen MG. Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor. The Embo Journal. 16: 4606-16. PMID 9303305 DOI: 10.1093/Emboj/16.15.4606  0.306
1997 Bieniasz PD, Fridell RA, Anthony K, Cullen BR. Murine CXCR-4 is a functional coreceptor for T-cell-tropic and dual- tropic strains of human immunodeficiency virus type 1 Journal of Virology. 71: 7097-7100. PMID 9261443 DOI: 10.1128/Jvi.71.9.7097-7100.1997  0.393
1997 Hua J, Cullen BR. Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4 Journal of Virology. 71: 6742-6748. PMID 9261398 DOI: 10.1128/Jvi.71.9.6742-6748.1997  0.331
1997 Bieniasz PD, Fridell RA, Aramori I, Ferguson SS, Caron MG, Cullen BR. HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. The Embo Journal. 16: 2599-609. PMID 9184207 DOI: 10.1093/Emboj/16.10.2599  0.36
1997 Hua J, Blair W, Truant R, Cullen BR. Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4. Virology. 231: 231-8. PMID 9168885 DOI: 10.1006/Viro.1997.8517  0.305
1997 Blair WS, Cullen BR. A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters Molecular and Cellular Biology. 17: 2888-2896. PMID 9111361 DOI: 10.1128/Mcb.17.5.2888  0.376
1996 Cullen BR. HIV-1: Is Nef a PAK animal? Current Biology. 6: 1557-1559. PMID 8994811 DOI: 10.1016/S0960-9822(02)70770-7  0.387
1996 Hua J, Cafffey JJ, Cullen BR. Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev Virology. 222: 423-429. PMID 8806526 DOI: 10.1006/Viro.1996.0439  0.358
1996 Bogerd HP, Fridell RA, Benson RE, Hua J, Cullen BR. Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay. Molecular and Cellular Biology. 16: 4207-14. PMID 8754820 DOI: 10.1128/Mcb.16.8.4207  0.346
1996 Fengling HE, Blair WS, Fukushima J, Cullen BR. The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein Journal of Virology. 70: 3902-3908. PMID 8648727 DOI: 10.1128/Jvi.70.6.3902-3908.1996  0.362
1996 Fridell RA, Bogerd HP, Cullen BR. Nuclear export of late HIV-1 mRNAs occurs via a cellular protein export pathway Proceedings of the National Academy of Sciences of the United States of America. 93: 4421-4424. PMID 8633082 DOI: 10.1073/Pnas.93.9.4421  0.414
1996 Blair WS, Fridell RA, Cullen BR. Synergistic enhancement of both initiation and elongation by acidic transcription activation domains Embo Journal. 15: 1658-1665. PMID 8612590 DOI: 10.1002/J.1460-2075.1996.Tb00511.X  0.357
1996 Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR. Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 rev Proceedings of the National Academy of Sciences of the United States of America. 93: 2936-2940. PMID 8610146 DOI: 10.1073/Pnas.93.7.2936  0.434
1996 Fridell RA, Benson RE, Hua J, Bogerd HP, Cullen BR. A nuclear role for the Fragile X mental retardation protein. The Embo Journal. 15: 5408-5414. DOI: 10.1002/J.1460-2075.1996.Tb00924.X  0.429
1995 Madore SJ, Cullen BR. Functional Similarities between HIV-1 Tat and DNA Sequence-Specific Transcriptional Activators Virology. 206: 1150-1154. PMID 7856090 DOI: 10.1006/Viro.1995.1041  0.421
1995 Fridell RA, Harding LS, Bogerd HP, Cullen BR. Identification of a Novel Human Zinc Finger Protein That Specifically Interacts with the Activation Domain of Lentiviral Tat Proteins Virology. 209: 347-357. PMID 7778269 DOI: 10.1006/Viro.1995.1266  0.381
1995 Bogerd HP, Fridell RA, Madore S, Cullen BR. Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins Cell. 82: 485-494. PMID 7634337 DOI: 10.1016/0092-8674(95)90437-9  0.393
1995 Okuda K, Bukawa H, Hamajima K, Kawamoto S, Sekigawa K, Yamada Y, Tanaka S, Ishii N, Aoki I, Nakamura M, Yamamoto H, Cullen BR, Fukushima J. Induction of potent humoral and cell-mediated immune responses following direct injection of DNA encoding the HIV type 1 env and rev gene products. Aids Research and Human Retroviruses. 11: 933-943. PMID 7492440 DOI: 10.1089/Aid.1995.11.933  0.357
1994 Paca-Uccaralertkun S, Zhao LJ, Adya N, Cross JV, Cullen BR, Boros IM, Giam CZ. In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax. Molecular and Cellular Biology. 14: 456-62. PMID 8264613 DOI: 10.1128/Mcb.14.1.456  0.339
1994 Blair WS, Bogerd H, Cullen BR. Genetic analysis indicates that the human foamy virus Bel-1 protein contains a transcription activation domain of the acidic class Journal of Virology. 68: 3803-3808. PMID 8189518 DOI: 10.1128/Jvi.68.6.3803-3808.1994  0.359
1994 Gröne M, Hoffmann E, Berchtold S, Cullen BR, Grassmann R. A single stem-loop structure within the HTLV-1 Rex response element is sufficient to mediate Rex activity in vivo. Virology. 204: 144-52. PMID 8091649 DOI: 10.1006/Viro.1994.1518  0.381
1994 Cullen BR. The Role of Nef in the Replication Cycle of the Human and Simian Immunodeficiency Viruses Virology. 205: 1-6. PMID 7975204 DOI: 10.1006/Viro.1994.1613  0.362
1994 Cullen BR. RNA-sequence-mediated gene regulation in HIV-1 Infectious Agents and Disease. 3: 68-76. PMID 7812657  0.374
1994 Madore SJ, Tiley LS, Malim MH, Cullen BR. Sequence Requirements for Rev Multimerization in Vivo Virology. 202: 186-194. PMID 7516596 DOI: 10.1006/Viro.1994.1334  0.418
1993 Cullen BR. Does HIV-1 Tat induce a change in viral initiation rights? Cell. 73: 417-420. PMID 8490957 DOI: 10.1016/0092-8674(93)90126-B  0.34
1993 Garrett ED, He F, Bogerd HP, Cullen BR. Transcriptional trans activators of human and simian foamy viruses contain a small, highly conserved activation domain Journal of Virology. 67: 6824-6827. PMID 8411385 DOI: 10.1128/Jvi.67.11.6824-6827.1993  0.381
1993 Madore SJ, Cullen BR. Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function Journal of Virology. 67: 3703-3711. PMID 8389901 DOI: 10.1128/Jvi.67.7.3703-3711.1993  0.477
1993 He F, Sun JD, Garrett ED, Cullen BR. Functional organization of the Bel-1 trans activator of human foamy virus Journal of Virology. 67: 1896-1904. PMID 8383217 DOI: 10.1128/Jvi.67.4.1896-1904.1993  0.387
1993 Luo Y, Madore SJ, Parslow TG, Cullen BR, Peterlin BM. Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells Journal of Virology. 67: 5617-5622. PMID 8350414 DOI: 10.1128/Jvi.67.9.5617-5622.1993  0.462
1993 Bogerd HP, Fridell RA, Blair WS, Cullen BR. Genetic evidence that the Tat proteins of human immunodeficiency virus types 1 and 2 can multimerize in the eukaryotic cell nucleus Journal of Virology. 67: 5030-5034. PMID 8331738 DOI: 10.1128/Jvi.67.8.5030-5034.1993  0.403
1993 Fridell RA, Partin KM, Carpenter S, Cullen BR. Identification of the activation domain of equine infectious anemia virus rev. Journal of Virology. 67: 7317-23. PMID 8230455 DOI: 10.1128/Jvi.67.12.7317-7323.1993  0.402
1993 Malim MH, Cullen BR. Rev and the fate of pre-mRNA in the nucleus: Implications for the regulation of RNA processing in eukaryotes Molecular and Cellular Biology. 13: 6180-6189. PMID 8105371 DOI: 10.1128/Mcb.13.10.6180  0.456
1993 Benson RE, Sanfridson A, Ottinger JS, Doyle C, Cullen BR. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. The Journal of Experimental Medicine. 177: 1561-6. PMID 8098729 DOI: 10.1084/Jem.177.6.1561  0.404
1992 Tiley LS, Malim MH, Tewary HK, Stockley PG, Cullen BR. Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proceedings of the National Academy of Sciences of the United States of America. 89: 758-62. PMID 1731351 DOI: 10.1073/Pnas.89.2.758  0.389
1992 Hwang SS, Boyle TJ, Lyerly HK, Cullen BR. Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1. Science (New York, N.Y.). 257: 535-7. PMID 1636088 DOI: 10.1126/Science.1636088  0.333
1992 Garrett ED, Cullen BR. Comparative analysis of Rev function in human immunodeficiency virus types 1 and 2 Journal of Virology. 66: 4288-4294. PMID 1602545 DOI: 10.1128/Jvi.66.7.4288-4294.1992  0.391
1992 Chen H, Boyle TJ, Malim MH, Cullen BR, Lyerly HK. Derivation of a biologically contained replication system for human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 89: 7678-7682. PMID 1502183 DOI: 10.1073/Pnas.89.16.7678  0.434
1992 Bogerd HP, Tiley LS, Cullen BR. Specific binding of the human T-cell leukemia virus type I Rex protein to a short RNA sequence located within the Rex-response element Journal of Virology. 66: 7572-7575. PMID 1433531 DOI: 10.1128/Jvi.66.12.7572-7575.1992  0.439
1992 Tiley LS, Madore SJ, Malim MH, Cullen BR. The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence Genes and Development. 6: 2077-2087. PMID 1427073 DOI: 10.1101/Gad.6.11.2077  0.441
1992 Cullen BR. Mechanism of action of regulatory proteins encoded by complex retroviruses Microbiological Reviews. 56: 375-394. PMID 1406488 DOI: 10.1128/Mmbr.56.3.375-394.1992  0.423
1992 Malim MH, Freimuth WW, Liu J, Boyle TJ, Lyerly HK, Cullen BR, Nabel GJ. Stable expression of transdominant rev protein in human T cells inhibits human immunodeficiency virus replication Journal of Experimental Medicine. 176: 1197-1201. PMID 1402661 DOI: 10.1084/Jem.176.4.1197  0.442
1992 Keller A, Garrett ED, Cullen BR. The Bel-1 protein of human foamy virus activates human immunodeficiency virus type 1 gene expression via a novel DNA target site Journal of Virology. 66: 3946-3949. PMID 1316494 DOI: 10.1128/Jvi.66.6.3946-3949.1992  0.455
1992 Tiley LS, Cullen BR. Structural and functional analysis of the visna virus rev-response element Journal of Virology. 66: 3609-3615. PMID 1316470 DOI: 10.1128/Jvi.66.6.3609-3615.1992  0.463
1992 Cullen BR, Garrett ED. A comparison of regulatory features in primate lentiviruses Aids Research and Human Retroviruses. 8: 387-393. PMID 1315144 DOI: 10.1089/Aid.1992.8.387  0.402
1991 Malim MH, McCarn DF, Tiley LS, Cullen BR. Mutational definition of the human immunodeficiency virus type 1 Rev activation domain Journal of Virology. 65: 4248-4254. PMID 2072452 DOI: 10.1128/Jvi.65.8.4248-4254.1991  0.445
1991 Kubota S, Nosaka T, Cullen BR, Maki M, Hatanaka M. Effects of chimeric mutants of human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex on nucleolar targeting signals. Journal of Virology. 65: 2452-6. PMID 2016767 DOI: 10.1128/Jvi.65.5.2452-2456.1991  0.388
1991 Malim MH, Cullen BR. HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency Cell. 65: 241-248. PMID 2015625 DOI: 10.1016/0092-8674(91)90158-U  0.438
1991 Cullen BR. Human immunodeficiency virus as a prototypic complex retrovirus. Journal of Virology. 65: 1053-6. PMID 1995941 DOI: 10.1128/Jvi.65.3.1053-1056.1991  0.355
1991 Cullen BR. Regulation of gene expression in the human immunodeficiency virus type 1 Advances in Virus Research. 40: 1-17. PMID 1957716 DOI: 10.1016/S0065-3527(08)60275-4  0.431
1991 Cullen BR, Malim MH. The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators Trends in Biochemical Sciences. 16: 346-350. PMID 1949157 DOI: 10.1016/0968-0004(91)90141-H  0.461
1991 Hwang SS, Boyle TJ, Lyerly HK, Cullen BR. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1 Science. 253: 71-74. PMID 1905842 DOI: 10.1126/Science.1905842  0.372
1991 Brown PH, Tiley LS, Cullen BR. Efficient Polyadenylation within the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Requires Flanking US-Specific Sequences Journal of Virology. 65: 3340-3343. PMID 1851882 DOI: 10.1128/Jvi.65.6.3340-3343.1991  0.379
1991 Keller A, Partin KM, Löchelt M, Bannert H, Flügel RM, Cullen BR. Characterization of the transcriptional trans activator of human foamy retrovirus. Journal of Virology. 65: 2589-94. PMID 1850032 DOI: 10.1128/Jvi.65.5.2589-2594.1991  0.419
1991 Garrett ED, Tiley LS, Cullen BR. Rev activates expression of the human immunodeficiency virus type 1 vif and vpr gene products Journal of Virology. 65: 1653-1657. PMID 1825343 DOI: 10.1128/Jvi.65.3.1653-1657.1991  0.46
1991 Cullen BR. Regulation of human immunodeficiency virus replication Annual Review of Microbiology. 45: 219-250. PMID 1741615 DOI: 10.1146/Annurev.Mi.45.100191.001251  0.404
1991 Weinberg JB, Matthews TJ, Cullen BR, Malim MH. Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes Journal of Experimental Medicine. 174: 1477-1482. PMID 1720811 DOI: 10.1084/Jem.174.6.1477  0.381
1991 Brown PH, Tiley LS, Cullen BR. Effect of RNA secondary structure on polyadenylation site selection Genes and Development. 5: 1277-1284. PMID 1712333 DOI: 10.1101/Gad.5.7.1277  0.333
1991 Cullen BR. Regulation of HIV-1 gene expression Faseb Journal. 5: 2361-2368. PMID 1712325 DOI: 10.1096/Fasebj.5.10.1712325  0.435
1991 Garcia-Blanco MA, Cullen BR. Molecular basis of latency in pathogenic human viruses Science. 254: 815-820. PMID 1658933 DOI: 10.1126/Science.1658933  0.459
1991 Tiley LS, Malim MH, Cullen BR. Conserved functional organization of the human immunodeficiency virus type 1 and visna virus Rev proteins Journal of Virology. 65: 3877-3881. PMID 1645796 DOI: 10.1128/Jvi.65.7.3877-3881.1991  0.408
1990 Malim MH, Tiley LS, McCarn DF, Rusche JR, Hauber J, Cullen BR. HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence Cell. 60: 675-683. PMID 2406030 DOI: 10.1016/0092-8674(90)90670-A  0.441
1990 Le SY, Malim MH, Cullen BR, Maizel JV. A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses Nucleic Acids Research. 18: 1613-1623. PMID 2326200 DOI: 10.1093/Nar/18.6.1613  0.433
1990 Cullen BR. The HIV-1 Tat protein: An RNA sequence-specific processivity factor? Cell. 63: 655-657. PMID 2225069 DOI: 10.1016/0092-8674(90)90129-3  0.413
1990 Tiley LS, Brown PH, Cullen BR. Does the human immunodeficiency virus tat trans-activator contain a discrete activation domain? Virology. 178: 560-567. PMID 2219707 DOI: 10.1016/0042-6822(90)90354-T  0.403
1990 Cullen BR, Greene WC. Functions of the auxiliary gene products of the human immunodeficiency virus type 1 Virology. 178: 1-5. PMID 2202146 DOI: 10.1016/0042-6822(90)90373-Y  0.357
1990 Tiley LS, Brown PH, Shu-Yun Le, Maizel JV, Clements JE, Cullen BR. Visna virus encodes a post-transcriptional regulator of viral structural gene expression Proceedings of the National Academy of Sciences of the United States of America. 87: 7497-7501. PMID 2170981 DOI: 10.1073/Pnas.87.19.7497  0.494
1990 Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: Insights into the mechanism of Rex and Rev action Genes and Development. 4: 1014-1022. PMID 2116986 DOI: 10.1101/Gad.4.6.1014  0.455
1990 Tiley LS, Brown PH, Le S, Maizel JV, Clements JE, Cullen BR. Correction and Clarification: Visna Virus Encodes a Post-Transcriptional Regulator of Viral Structural Gene Expression Proceedings of the National Academy of Sciences of the United States of America. 87: 9508. DOI: 10.1073/Pnas.87.23.9508D  0.408
1989 Bohnlein S, Hauber J, Cullen BR. Identification of a U5-specific sequence required for efficient polyadenylation within the human immunodeficiency virus long terminal repeat Journal of Virology. 63: 421-424. PMID 2908926 DOI: 10.1128/Jvi.63.1.421-424.1989  0.371
1989 Malim MH, Hauber J, Le SY, Maizel JV, Cullen BR. The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA Nature. 338: 254-257. PMID 2784194 DOI: 10.1038/338254A0  0.471
1989 Malim MH, Böhnlein S, Hauber J, Cullen BR. Functional dissection of the HIV-1 Rev trans-activator-Derivation of a trans-dominant repressor of Rev function Cell. 58: 205-214. PMID 2752419 DOI: 10.1016/0092-8674(89)90416-9  0.421
1989 Sadaie MR, Benaissa ZN, Cullen BR, Wong-Staal F. Human immunodeficiency virus type 1 rev protein as a negative trans-regulator Dna. 8: 669-674. PMID 2693023 DOI: 10.1089/dna.1.1989.8.669  0.373
1989 Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. Nef protein of human immunodeficiency virus type 1: Evidence against its role as a transcriptional inhibitor Proceedings of the National Academy of Sciences of the United States of America. 86: 9549-9553. PMID 2687884 DOI: 10.1073/Pnas.86.23.9549  0.441
1989 Malim MH, Bohnlein S, Fenrick R, Le SY, Maizel JV, Cullen BR. Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species Proceedings of the National Academy of Sciences of the United States of America. 86: 8222-8226. PMID 2682638 DOI: 10.1073/Pnas.86.21.8222  0.424
1989 Cullen BR, Greene WC. Regulatory pathways governing HIV-1 replication Cell. 58: 423-426. PMID 2569361 DOI: 10.1016/0092-8674(89)90420-0  0.333
1989 Fenrick R, Malim MH, Hauber J, Le SY, Maizel J, Cullen BR. Functional analysis of the Tat trans activator of human immunodeficiency virus type 2 Journal of Virology. 63: 5006-5012. PMID 2555537 DOI: 10.1128/Jvi.63.12.5006-5012.1989  0.395
1989 Malim MH, Fenrick R, Ballard DW, Hauber J, Bohnlein E, Cullen BR. Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region Journal of Virology. 63: 3213-3219. PMID 2545899 DOI: 10.1128/Jvi.63.8.3213-3219.1989  0.398
1989 Hauber J, Malim MH, Cullen BR. Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein Journal of Virology. 63: 1181-1187. PMID 2536828 DOI: 10.1128/Jvi.63.3.1181-1187.1989  0.42
1989 Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements Genes &Amp; Development. 3: 1534-1544. PMID 2482226 DOI: 10.1101/Gad.3.10.1534  0.445
1988 Berger J, Hauber J, Hauber R, Geiger R, Cullen BR. Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells. Gene. 66: 1-10. PMID 3417148 DOI: 10.1016/0378-1119(88)90219-3  0.309
1988 Malim MH, Hauber J, Fenrick R, Cullen BR. Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes Nature. 335: 181-183. PMID 3412474 DOI: 10.1038/335181A0  0.464
1988 Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein Nature. 335: 738-740. PMID 3262832 DOI: 10.1038/335738A0  0.453
1988 Hauber J, Bouvier M, Malim MH, Cullen BR. Phosphorylation of the rev gene product of human immunodeficiency virus type 1 Journal of Virology. 62: 4801-4804. PMID 2846891 DOI: 10.1128/Jvi.62.12.4801-4804.1988  0.391
1988 Cullen BR, Hauber J, Campbell K, Sodroski JG, Haseltine WA, Rosen CA. Subcellular localization of the human immunodeficiency virus trans-acting art gene product Journal of Virology. 62: 2498-2501. PMID 2836628 DOI: 10.1128/Jvi.62.7.2498-2501.1988  0.416
1988 Hauber J, Cullen BR. Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat Journal of Virology. 62: 673-679. PMID 2828663 DOI: 10.1128/Jvi.62.3.673-679.1988  0.414
1987 Hauber J, Perkins A, Heimer EP, Cullen BR. Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events Proceedings of the National Academy of Sciences of the United States of America. 84: 6364-6368. PMID 3476953 DOI: 10.1073/Pnas.84.18.6364  0.465
1987 Berger J, Howard AD, Gerber L, Cullen BR, Udenfriend S. Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 4885-9. PMID 3474633 DOI: 10.1073/Pnas.84.14.4885  0.306
1986 Cullen BR. Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism Cell. 46: 973-982. PMID 3530501 DOI: 10.1016/0092-8674(86)90696-3  0.41
1986 Katz RA, Cullen BR, Malavarca R, Skalka AM. Role of the avian retrovirus mRNA leader in expression: Evidence for novel translational control Molecular and Cellular Biology. 6: 372-379. PMID 3023842 DOI: 10.1128/Mcb.6.2.372  0.39
1985 Butnick NZ, Miyamoto C, Chizzonite R, Cullen BR, Ju G, Skalka AM. Regulation of the human c-myc gene: 5' noncoding sequences do not affect translation Molecular and Cellular Biology. 5: 3009-3016. PMID 3018494 DOI: 10.1128/Mcb.5.11.3009  0.348
1985 Ju G, Cullen BR. The role of avian retroviral LTRs in the regulation of gene expression and viral replication Advances in Virus Research. 30: 179-223. PMID 3008523 DOI: 10.1016/S0065-3527(08)60451-0  0.401
1985 Cullen BR, Katz RA, Ju G. Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection Molecular and Cellular Biology. 5: 1804-1807. PMID 2991753 DOI: 10.1128/Mcb.5.7.1804  0.346
1985 Cullen BR, Raymond K, Ju G. Functional analysis of the transcription control region located within the avian retroviral long terminal repeat Molecular and Cellular Biology. 5: 438-447. PMID 2985953 DOI: 10.1128/Mcb.5.3.438  0.304
1985 Cullen BR, Raymond K, Ju G. Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity Journal of Virology. 53: 515-521. PMID 2982034 DOI: 10.1128/Jvi.53.2.515-521.1985  0.374
1984 Cullen BR, Lomedico PT, Ju G. Transcriptional interference in avian retroviruses - implications for the promoter insertion model of leukaemogenesis Nature. 307: 241-245. PMID 6363938 DOI: 10.1038/307241A0  0.353
1983 Cullen BR, Skalka AM, Ju G. Endogenous avian retroviruses contain deficient promoter and leader sequences Proceedings of the National Academy of Sciences of the United States of America. 80: 2946-2950. PMID 6574464 DOI: 10.1073/Pnas.80.10.2946  0.398
1982 Cullen BR, Kopchick JJ, Stacey DW. Effect of intron size on splicing efficiency in retroviral transcripts Nucleic Acids Research. 10: 6177-6190. PMID 6292870 DOI: 10.1093/Nar/10.19.6177  0.387
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