Constance E. Brinckerhoff - Publications

Affiliations: 
Biochemistry Dartmouth College, Hanover, NH, United States 
Area:
Molecular Biology

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, ... ... Brinckerhoff CE, et al. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Science Translational Medicine. 13. PMID 33597266 DOI: 10.1126/scitranslmed.abd8636  0.569
2019 Bellmann L, Cappellano G, Schachtl-Riess JF, Prokopi A, Seretis A, Ortner D, Tripp CH, Brinckerhoff CE, Mullins DW, Stoitzner P. A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model. International Journal of Cancer. PMID 31702822 DOI: 10.1002/Ijc.32777  0.587
2016 Brinckerhoff CE. What are the therapeutic implications of increased collagen expression in melanoma cells treated with vemurafenib? Melanoma Management. 3: 5-8. PMID 30190867 DOI: 10.2217/mmt.15.36  0.312
2016 Whipple CA, Boni A, Fisher JL, Hampton TH, Tsongalis GJ, Mellinger DL, Yan S, Tafe LJ, Brinckerhoff CE, Turk MJ, Mullins DW, Fadul CE, Ernstoff MS. The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells. Melanoma Research. PMID 26974965 DOI: 10.1097/Cmr.0000000000000244  0.605
2015 Jenkins MH, Croteau W, Mullins DW, Brinckerhoff CE. The BRAF(V600E) inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells. Matrix Biology : Journal of the International Society For Matrix Biology. 48: 66-77. PMID 25989506 DOI: 10.1016/J.Matbio.2015.05.007  0.645
2015 Jenkins MH, Brinckerhoff CE, Mullins DW. CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and tumorigenicity. Plos One. 10: e0121140. PMID 25798946 DOI: 10.1371/Journal.Pone.0121140  0.604
2014 Steinberg SM, Zhang P, Malik BT, Boni A, Shabaneh TB, Byrne KT, Mullins DW, Brinckerhoff CE, Ernstoff MS, Bosenberg MW, Turk MJ. BRAF inhibition alleviates immune suppression in murine autochthonous melanoma. Cancer Immunology Research. 2: 1044-50. PMID 25183499 DOI: 10.1158/2326-6066.Cir-14-0074  0.591
2014 Jenkins MH, Steinberg SM, Alexander MP, Fisher JL, Ernstoff MS, Turk MJ, Mullins DW, Brinckerhoff CE. Multiple murine BRaf(V600E) melanoma cell lines with sensitivity to PLX4032. Pigment Cell & Melanoma Research. 27: 495-501. PMID 24460976 DOI: 10.1111/Pcmr.12220  0.625
2013 Croteau W, Jenkins MH, Ye S, Mullins DW, Brinckerhoff CE. Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma. Journal of Cellular Physiology. 228: 773-80. PMID 23001823 DOI: 10.1002/Jcp.24225  0.644
2012 Schmucker AC, Wright JB, Cole MD, Brinckerhoff CE. Distal interleukin-1β (IL-1β) response element of human matrix metalloproteinase-13 (MMP-13) binds activator protein 1 (AP-1) transcription factors and regulates gene expression. The Journal of Biological Chemistry. 287: 1189-97. PMID 22102411 DOI: 10.1074/Jbc.M111.264077  0.357
2009 Schmucker AC, Brinckerhoff CE. The 'RASor's' edge: Ras proteins and matrix destruction in arthritis. Arthritis Research & Therapy. 11: 136. PMID 20067598 DOI: 10.1186/Ar2840  0.346
2009 Eck SM, Blackburn JS, Schmucker AC, Burrage PS, Brinckerhoff CE. Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer. Journal of Autoimmunity. 33: 214-21. PMID 19800199 DOI: 10.1016/j.jaut.2009.09.011  0.315
2009 Blackburn JS, Liu I, Coon CI, Brinckerhoff CE. A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis. Oncogene. 28: 4237-48. PMID 19734937 DOI: 10.1038/Onc.2009.272  0.467
2009 Coon CI, Fiering S, Gaudet J, Wyatt CA, Brinckerhoff CE. Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 425-31. PMID 19577645 DOI: 10.1016/j.matbio.2009.06.003  0.317
2009 Blackburn JS, Brinckerhoff CE. Wild-type versus mutant MMP-8 in melanoma: 'when you come to a fork in the road, take it'. Pigment Cell & Melanoma Research. 22: 248-50. PMID 19397759 DOI: 10.1111/J.1755-148X.2009.00573.X  0.473
2009 Li J, Ghio AJ, Cho SH, Brinckerhoff CE, Simon SA, Liedtke W. Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS. Environmental Health Perspectives. 117: 400-9. PMID 19337515 DOI: 10.1289/Ehp.0800311  0.322
2009 Eck SM, Hoopes PJ, Petrella BL, Coon CI, Brinckerhoff CE. Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model. Breast Cancer Research and Treatment. 116: 79-90. PMID 18597171 DOI: 10.1007/S10549-008-0085-3  0.407
2008 Burrage PS, Schmucker AC, Ren Y, Sporn MB, Brinckerhoff CE. Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression. Arthritis Research & Therapy. 10: R139. PMID 19046432 DOI: 10.1186/Ar2564  0.427
2008 Blackburn JS, Brinckerhoff CE. Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis. The American Journal of Pathology. 173: 1736-46. PMID 18988801 DOI: 10.2353/Ajpath.2008.080512  0.484
2007 Blackburn JS, Rhodes CH, Coon CI, Brinckerhoff CE. RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis. Cancer Research. 67: 10849-58. PMID 18006830 DOI: 10.1158/0008-5472.Can-07-1791  0.487
2007 Vincenti MP, Brinckerhoff CE. Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you? Journal of Cellular Physiology. 213: 355-64. PMID 17654499 DOI: 10.1002/jcp.21208  0.344
2007 Mix KS, Attur MG, Al-Mussawir H, Abramson SB, Brinckerhoff CE, Murphy EP. Transcriptional repression of matrix metalloproteinase gene expression by the orphan nuclear receptor NURR1 in cartilage. The Journal of Biological Chemistry. 282: 9492-504. PMID 17283078 DOI: 10.1074/Jbc.M608327200  0.469
2006 Petrella BL, Brinckerhoff CE. Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase. Molecular Cancer. 5: 66. PMID 17140440 DOI: 10.1186/1476-4598-5-66  0.458
2006 Burrage PS, Mix KS, Brinckerhoff CE. Matrix metalloproteinases: role in arthritis. Frontiers in Bioscience : a Journal and Virtual Library. 11: 529-43. PMID 16146751 DOI: 10.2741/1817  0.439
2005 Wyatt CA, Geoghegan JC, Brinckerhoff CE. Short hairpin RNA-mediated inhibition of matrix metalloproteinase-1 in MDA-231 cells: effects on matrix destruction and tumor growth. Cancer Research. 65: 11101-8. PMID 16322260 DOI: 10.1158/0008-5472.CAN-05-2446  0.375
2005 Petrella BL, Lohi J, Brinckerhoff CE. Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma. Oncogene. 24: 1043-52. PMID 15592504 DOI: 10.1038/Sj.Onc.1208305  0.444
2004 Mix KS, Sporn MB, Brinckerhoff CE, Eyre D, Schurman DJ. Novel inhibitors of matrix metalloproteinase gene expression as potential therapies for arthritis. Clinical Orthopaedics and Related Research. S129-37. PMID 15480055 DOI: 10.1097/01.Blo.0000144483.62033.8B  0.422
2004 Huntington JT, Shields JM, Der CJ, Wyatt CA, Benbow U, Slingluff CL, Brinckerhoff CE. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling. The Journal of Biological Chemistry. 279: 33168-76. PMID 15184373 DOI: 10.1074/Jbc.M405102200  0.407
2004 Mix KS, Coon CI, Rosen ED, Suh N, Sporn MB, Brinckerhoff CE. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. Molecular Pharmacology. 65: 309-18. PMID 14742672 DOI: 10.1124/Mol.65.2.309  0.437
2003 Tower GB, Coon CI, Brinckerhoff CE. The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells. Breast Cancer Research and Treatment. 82: 75-82. PMID 14692651 DOI: 10.1023/B:Brea.0000003948.14026.7C  0.425
2003 Tower GB, Coon CI, Belguise K, Chalbos D, Brinckerhoff CE. Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter. European Journal of Biochemistry / Febs. 270: 4216-25. PMID 14519134 DOI: 10.1046/J.1432-1033.2003.03821.X  0.395
2002 Wyatt CA, Coon CI, Gibson JJ, Brinckerhoff CE. Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells. Cancer Research. 62: 7200-2. PMID 12499258  0.339
2002 Benbow U, Tower GB, Wyatt CA, Buttice G, Brinckerhoff CE. High levels of MMP-1 expression in the absence of the 2G single nucleotide polymorphism is mediated by p38 and ERK1/2 mitogen-activated protein kinases in VMM5 melanoma cells. Journal of Cellular Biochemistry. 86: 307-19. PMID 12112000 DOI: 10.1002/Jcb.10225  0.365
2002 Vincenti MP, Brinckerhoff CE. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Research. 4: 157-64. PMID 12010565 DOI: 10.1186/Ar401  0.454
2002 Tower GB, Coon CC, Benbow U, Vincenti MP, Brinckerhoff CE. Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells. Biochimica Et Biophysica Acta. 1586: 265-74. PMID 11997078 DOI: 10.1016/S0925-4439(01)00105-3  0.483
2002 Brinckerhoff CE, Matrisian LM. Matrix metalloproteinases: a tail of a frog that became a prince. Nature Reviews. Molecular Cell Biology. 3: 207-14. PMID 11994741 DOI: 10.1038/Nrm763  0.378
2002 Mengshol JA, Mix KS, Brinckerhoff CE. Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark? Arthritis and Rheumatism. 46: 13-20. PMID 11817584 DOI: 10.1002/1529-0131(200201)46:1<13::Aid-Art497>3.0.Co;2-S  0.302
2002 Tobin SW, Douville K, Benbow U, Brinckerhoff CE, Memoli VA, Arrick BA. Consequences of altered TGF-beta expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects. Oncogene. 21: 108-18. PMID 11791181 DOI: 10.1038/Sj.Onc.1205026  0.312
2001 Vincenti MP, Brinckerhoff CE. Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1β Arthritis Research. 3: 381-388. PMID 11714393 DOI: 10.1186/Ar331  0.397
2001 Mengshol JA, Vincenti MP, Brinckerhoff CE. IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: Requirement for Runx-2 and activation by p38 MAPK and JNK pathways Nucleic Acids Research. 29: 4361-4372. PMID 11691923 DOI: 10.1093/Nar/29.21.4361  0.437
2001 Catterall JB, Carrère S, Koshy PJT, Degnan BA, Shingleton WD, Brinckerhoff CE, Rutter J, Cawston TE, Rowan AD. Synergistic induction of matrix metalloproteinase 1 by interleukin-1α and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism Arthritis and Rheumatism. 44: 2296-2310. PMID 11665970 DOI: 10.1002/1529-0131(200110)44:10<2296::Aid-Art392>3.0.Co;2-9  0.471
2001 Vincenti MP, Brinckerhoff CE. The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK? Journal of Clinical Investigation. 108: 181-183. PMID 11457869 DOI: 10.1172/Jci13508  0.517
2001 Mix KS, Mengshol JA, Benbow U, Vincenti MP, Sporn MB, Brinckerhoff CE. A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokines Arthritis and Rheumatism. 44: 1096-1104. PMID 11352241 DOI: 10.1002/1529-0131(200105)44:5<1096::Aid-Anr190>3.0.Co;2-6  0.464
2001 Ranganathan AC, Nelson KK, Rodriguez AM, Kim KH, Tower GB, Rutter JL, Brinckerhoff CE, Huang TT, Epstein CJ, Jeffrey JJ, Melendez JA. Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. The Journal of Biological Chemistry. 276: 14264-70. PMID 11297530 DOI: 10.1074/Jbc.M100199200  0.341
2000 Benbow U, Orndorff KA, Brinckerhoff CE, Givan AL. Confocal assay for invasion: Use of propidium iodide fluorescence and laser reflectance to quantify the rate of migration of cells through a matrix Cytometry. 40: 253-259. PMID 10918276 DOI: 10.1002/1097-0320(20000801)40:4<253::Aid-Cyto1>3.0.Co;2-M  0.331
2000 Mengshol JA, Vincenti MP, Coon CI, Barchowsky A, Brinckerhoff CE. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor κB: Differential regulation of collagenase 1 and collagenase 3 Arthritis and Rheumatism. 43: 801-811. PMID 10765924 DOI: 10.1002/1529-0131(200004)43:4<801::Aid-Anr10>3.0.Co;2-4  0.454
2000 White LA, Mitchell TI, Brinckerhoff CE. Transforming growth factor beta inhibitory element in the rabbit matrix metalloproteinase-1 (collagenase-1) gene functions as a repressor of constitutive transcription. Biochimica Et Biophysica Acta. 1490: 259-68. PMID 10684971 DOI: 10.1016/S0167-4781(00)00002-6  0.418
1999 Benbow U, Schoenermark MP, Mitchell TI, Rutter JL, Shimokawa K, Nagase H, Brinckerhoff CE. A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagen. The Journal of Biological Chemistry. 274: 25371-8. PMID 10464264 DOI: 10.1074/Jbc.274.36.25371  0.473
1999 Benbow U, Schoenermark MP, Orndorff KA, Givan AL, Brinckerhoff CE. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clinical & Experimental Metastasis. 17: 231-8. PMID 10432008 DOI: 10.1023/A:1006639214618  0.463
1999 Sun Y, Sun Y, Wenger L, Rutter JL, Brinckerhoff CE, Cheung HS. Human metalloproteinase-1 (collagenase-1) is a tumor suppressor protein p53 target gene. Annals of the New York Academy of Sciences. 878: 638-41. PMID 10415795 DOI: 10.1111/J.1749-6632.1999.Tb07749.X  0.336
1999 Schoenermark MP, Mitchell TI, Rutter JL, Reczek PR, Brinckerhoff CE. Retinoid-mediated suppression of tumor invasion and matrix metalloproteinase synthesis. Annals of the New York Academy of Sciences. 878: 466-86. PMID 10415749 DOI: 10.1111/J.1749-6632.1999.Tb07703.X  0.485
1999 Sun Y, Sun Y, Wenger L, Rutter JL, Brinckerhoff CE, Cheung HS. p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression. The Journal of Biological Chemistry. 274: 11535-40. PMID 10206959 DOI: 10.1074/Jbc.274.17.11535  0.401
1999 Benbow U, Rutter JL, Lowrey CH, Brinckerhoff CE. Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter. British Journal of Cancer. 79: 221-8. PMID 9888461 DOI: 10.1038/Sj.Bjc.6690037  0.381
1998 Vincenti MP, Coon CI, Brinckerhoff CE. Nuclear factor κB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1β-stimulated synovial fibroblasts Arthritis and Rheumatism. 41: 1987-1994. PMID 9811054 DOI: 10.1002/1529-0131(199811)41:11<1987::Aid-Art14>3.0.Co;2-8  0.419
1998 Vincenti MP, Schroen DJ, Coon CI, Brinckerhoff CE. v-src Activation of the collagenase-1 (matrix metalloproteinase-1) promoter through PEA3 and STAT: Requirement of extracellular signal-regulated kinases and inhibition by retinoic acid receptors Molecular Carcinogenesis. 21: 194-204. PMID 9537651 DOI: 10.1002/(Sici)1098-2744(199803)21:3<194::Aid-Mc7>3.0.Co;2-M  0.456
1998 Vincenti MP, Coon CI, Mengshol JA, Yocum S, Mitchell P, Brinckerhoff CE. Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: Differential expression with collagenase-1 (matrix metalloproteinase-1) Biochemical Journal. 331: 341-346. PMID 9512498 DOI: 10.1042/Bj3310341  0.436
1998 Strissel KJ, Girard MT, West-Mays JA, Rinehart WB, Cook JR, Brinckerhoff CE, Fini ME. Role of serum amyloid A as an intermediate in the IL-1 and PMA-stimulated signaling pathways regulating expression of rabbit fibroblast collagenase. Experimental Cell Research. 237: 275-87. PMID 9434623 DOI: 10.1006/Excr.1997.3783  0.357
1997 White LA, Maute C, Brinckerhoff CE. ETS sites in the promoters of the matrix metalloproteinases collagenase (MMP-1) and stromelysin (MMP-3) are auxiliary elements that regulate basal and phorbol-induced transcription. Connective Tissue Research. 36: 321-35. PMID 9610890 DOI: 10.3109/03008209709160231  0.376
1997 Boyle DL, Han Z, Rutter JL, Brinckerhoff CE, Firestein GS. Posttranscriptional regulation of collagenase-1 gene expression in synoviocytes by adenosine receptor stimulation. Arthritis and Rheumatism. 40: 1772-9. PMID 9336410 DOI: 10.1002/Art.1780401008  0.308
1997 Schroen DJ, Don Chen J, Vincenti MP, Brinckerhoff CE. The nuclear receptor corepressor SMRT inhibits interstitial collagenase (MMP-1) transcription through an HRE-independent mechanism Biochemical and Biophysical Research Communications. 237: 52-58. PMID 9266828 DOI: 10.1006/Bbrc.1997.7073  0.46
1997 Rutter JL, Benbow U, Coon CI, Brinckerhoff CE. Cell-Type Specific Regulation of Human Interstitial Collagenase-1 Gene Expression by Interleukin-1β (IL-1β) in Human Fibroblasts and BC-8701 breast cancer cells Journal of Cellular Biochemistry. 66: 322-336. PMID 9257189 DOI: 10.1002/(Sici)1097-4644(19970901)66:3<322::Aid-Jcb5>3.0.Co;2-R  0.427
1997 Benbow U, Brinckerhoff CE. The AP-1 site and MMP gene regulation: what is all the fuss about? Matrix Biology : Journal of the International Society For Matrix Biology. 15: 519-26. PMID 9138284 DOI: 10.1016/S0945-053X(97)90026-3  0.425
1996 Vincenti MP, White LA, Schroen DJ, Benbow U, Brinckerhoff CE. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): Mechanisms that control enzyme activity, transcription, and mRNA stability Critical Reviews in Eukaryotic Gene Expression. 6: 391-411. PMID 8959374 DOI: 10.1615/Critreveukargeneexpr.V6.I4.40  0.441
1996 Schroen DJ, Brinckerhoff CE. Inhibition of rabbit collagenase (matrix metalloproteinase-1; MMP-1) transcription by retinoid receptors: evidence for binding of RARs/RXRs to the -77 AP-1 site through interactions with c-Jun. Journal of Cellular Physiology. 169: 320-32. PMID 8908199 DOI: 10.1002/(Sici)1097-4652(199611)169:2<320::Aid-Jcp11>3.0.Co;2-D  0.416
1996 Vincenti MP, Coon CI, White LA, Barchowsky A, Brinckerhoff CE. src-Related tyrosine kinases regulate transcriptional activation of the interstitial collagenase gene, MMP-1, in interleukin-1-stimulated synovial fibroblasts Arthritis and Rheumatism. 39: 574-582. PMID 8630105 DOI: 10.1002/Art.1780390406  0.386
1996 Sewell KL, Breedveld F, Furrie E, O'Brien J, Brinckerhoff C, Dynesius-Trentham R, Nosaka Y, Trentham DE. The effect of minocycline in rat models of inflammatory arthritis: Correlation of arthritis suppression with enhanced t cell calcium flux Cellular Immunology. 167: 195-204. PMID 8603428 DOI: 10.1006/Cimm.1996.0027  0.322
1995 White LA, Brinckerhoff CE. Two activator protein-1 elements in the matrix metalloproteinase-1 promoter have different effects on transcription and bind Jun D, c-Fos, and Fra-2. Matrix Biology : Journal of the International Society For Matrix Biology. 14: 715-25. PMID 8785586 DOI: 10.1016/S0945-053X(05)80014-9  0.361
1995 Pan L, Eckhoff C, Brinckerhoff CE. Suppression of collagenase gene expression by all-trans and 9-cis retinoic acid is ligand dependent and requires both RARs and RXRs. Journal of Cellular Biochemistry. 57: 575-89. PMID 7615643 DOI: 10.1002/Jcb.240570402  0.414
1995 Mitchell TI, Brinckerhoff CE. Saturable, high affinity binding of serum amyloid A (SAA3) to rabbit fibroblasts Amyloid. 2: 83-91. DOI: 10.3109/13506129509031892  0.335
1994 Vincenti MP, Clark IM, Brinckerhoff CE. Using inhibitors of metalloproteinases to treat arthritis: Easier said than done? Arthritis and Rheumatism. 37: 1115-1126. PMID 8053949 DOI: 10.1002/Art.1780370802  0.395
1994 Vincenti MP, Coon CI, Lee O, Brinckerhoff CE. Regulation of collagenase gene expression by IL-1β requires transcriptional and post-transcriptional mechanisms Nucleic Acids Research. 22: 4818-4827. PMID 7984435 DOI: 10.1093/Nar/22.22.4818  0.342
1994 Pan L, Brinckerhoff CE. Inhibition of collagenase gene expression in synovial fibroblasts by all-trans and 9-cis retinoic acid. Annals of the New York Academy of Sciences. 732: 335-47. PMID 7978803 DOI: 10.1111/J.1749-6632.1994.Tb24748.X  0.303
1993 Chamberlain SH, Hemmer RM, Brinckerhoff CE. Novel phorbol ester response region in the collagenase promoter binds Fos and Jun. Journal of Cellular Biochemistry. 52: 337-51. PMID 8366145 DOI: 10.1002/Jcb.240520310  0.302
1993 Delany AM, Brinckerhoff CE. The synthetic retinoid (4-hydroxyphenyl)retinamide decreases collagen expression in vitro and in the tight-skin mouse. Arthritis and Rheumatism. 36: 983-93. PMID 8318045 DOI: 10.1002/Art.1780360716  0.339
1993 James TW, Wagner R, White LA, Zwolak RM, Brinckerhoff CE. Induction of collagenase and stromelysin gene expression by mechanical injury in a vascular smooth muscle-derived cell line. Journal of Cellular Physiology. 157: 426-37. PMID 8227172 DOI: 10.1002/Jcp.1041570227  0.36
1993 Delany AM, Brinckerhoff CE. Post-transcriptional regulation of collagenase and stromelysin gene expression by epidermal growth factor and dexamethasone in cultured human fibroblasts. Journal of Cellular Biochemistry. 50: 400-10. PMID 1469071 DOI: 10.1002/Jcb.240500409  0.356
1992 Pan L, Chamberlain SH, Auble DT, Brinckerhoff CE. Differential regulation of collagenase gene expression by retinoic acid receptors - α, β and γ Nucleic Acids Research. 20: 3105-3111. PMID 1320254 DOI: 10.1093/Nar/20.12.3105  0.366
1991 Sirum-Connolly K, Brinckerhoff CE. Interleukin-1 or phorbol induction of the stromelysin promoter requires an element that cooperates with AP-1. Nucleic Acids Research. 19: 335-41. PMID 1901643 DOI: 10.1093/Nar/19.2.335  0.336
1991 Mitchell TI, Coon CI, Brinckerhoff CE. Serum Amyloid A (SAA3) produced by rabbit synovial fibroblasts treated with phorbol esters or interleukin 1 induces synthesis of collagenase and is neutralized with specific antiserum Journal of Clinical Investigation. 87: 1177-1185. PMID 1849144 DOI: 10.1172/Jci115116  0.364
1990 Sirum KL, Brinckerhoff CE. Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. Biochemistry. 28: 8691-8. PMID 2605216 DOI: 10.1021/Bi00448A004  0.407
1990 Brinckerhoff CE, Auble DT. Regulation of collagenase gene expression in synovial fibroblasts Annals of the New York Academy of Sciences. 580: 355-374. PMID 2159751 DOI: 10.1111/J.1749-6632.1990.Tb17944.X  0.336
1988 Murphy G, Nagase H, Brinckerhoff CE. Relationship of procollagenase activator, stromelysin and matrix metalloproteinase 3 Collagen and Related Research. 8: 389-391. PMID 2850888 DOI: 10.1016/S0174-173X(88)80009-8  0.36
1988 Brinckerhoff CE, Mitchell TI. Autocrine control of collagenase synthesis by synovial fibroblasts. Journal of Cellular Physiology. 136: 72-80. PMID 2840444 DOI: 10.1002/Jcp.1041360109  0.324
1987 Brinckerhoff CE, Ruby PL, Austin SD, Fini ME, White HD. Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA. The Journal of Clinical Investigation. 79: 542-6. PMID 3027129 DOI: 10.1172/Jci112845  0.332
1987 Brinckerhoff CE, Plucinska IM, Sheldon LA, O'Connor GT. Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retinoic acid or dexamethasone. Biochemistry. 25: 6378-84. PMID 3024708 DOI: 10.1021/Bi00369A006  0.307
1987 Fini ME, Karmilowicz MJ, Ruby PL, Beeman AM, Borges KA, Brinckerhoff CE. Cloning of a complementary DNA for rabbit proactivator. A metalloproteinase that activates synovial cell collagenase, shares homology with stromelysin and transin, and is coordinately regulated with collagenase. Arthritis and Rheumatism. 30: 1254-64. PMID 2825726 DOI: 10.1002/Art.1780301108  0.389
1986 Fini ME, Gross RH, Brinckerhoff CE. Characterization of rabbit genes for synovial cell collagenase. Arthritis and Rheumatism. 29: 1301-15. PMID 3022758 DOI: 10.1002/Art.1780291102  0.321
1985 Korn JH, Brinckerhoff CE, Edwards RL. Synthesis of PGE2, collagenase and tissue factor by fibroblast substrains: Substrains are differentially activated for different metabolic products Collagen and Related Research. 5: 437-447. PMID 3002712 DOI: 10.1016/S0174-173X(85)80031-5  0.312
1985 Brinckerhoff CE, Benoit MC, Culp WJ. Autoregulation of collagenase production by a protein synthesized and secreted by synovial fibroblasts: cellular mechanism for control of collagen degradation. Proceedings of the National Academy of Sciences of the United States of America. 82: 1916-20. PMID 2984672 DOI: 10.1073/Pnas.82.7.1916  0.308
1984 Gross RH, Sheldon LA, Fletcher CF, Brinckerhoff CE. Isolation of a collagenase cDNA clone and measurement of changing collagenase mRNA levels during induction in rabbit synovial fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 81: 1981-5. PMID 6326094 DOI: 10.1073/Pnas.81.7.1981  0.328
1983 Nagase H, Brinckerhoff CE, Vater CA, Harris ED. Biosynthesis and secretion of procollagenase by rabbit synovial fibroblasts. Inhibition of procollagenase secretion by monensin and evidence for glycosylation of procollagenase. The Biochemical Journal. 214: 281-8. PMID 6311179 DOI: 10.1042/Bj2140281  0.327
1982 Brinckerhoff CE, Nagel JE. Collagenase production by cloned populations of rabbit synovial fibroblasts. Collagen and Related Research. 1: 433-44. PMID 6286236 DOI: 10.1016/S0174-173X(81)80027-1  0.318
1982 Brinckerhoff CE, Gross RH, Nagase H, Sheldon L, Jackson RC, Harris ED. Increased level of translatable collagenase messenger ribonucleic acid in rabbit synovial fibroblasts treated with phorbol myristate acetate or crystals of monosodium urate monohydrate. Biochemistry. 21: 2674-9. PMID 6284207 DOI: 10.1021/Bi00540A015  0.338
1981 Harris E, Vater C, Brinckerhoff C, McMillan R, Hasselbacher P. Patterns of regulation of collagen breakdown in articular cartilage Seminars in Arthritis and Rheumatism. 11: 69-70. DOI: 10.1016/0049-0172(81)90046-9  0.305
1980 Brinckerhoff CE, McMillan RM, Dayer JM, Harris ED. Inhibition by retinoic acid of collagenase production in rheumatoid synovial cells. The New England Journal of Medicine. 303: 432-6. PMID 6248783 DOI: 10.1056/Nejm198008213030805  0.324
1979 Brinckerhoff CE, McMillan RM, Fahey JV, Harris ED. Collagenase production by synovial fibroblasts treated with phorbol myristate acetate. Arthritis and Rheumatism. 22: 1109-16. PMID 226097 DOI: 10.1002/Art.1780221010  0.322
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