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Svitlana Tyekucheva, Ph.D. - Publications

Affiliations: 
2008 Pennsylvania State University, State College, PA, United States 
Area:
Statistics, Biostatistics Biology
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Laajala TD, Sreekanth V, Soupir A, Creed J, Calboli FC, Singaravelu K, Orman M, Colin-Leitzinger C, Gerke T, Fidley BL, Tyekucheva S, Costello JC. curatedPCaData: Integration of clinical, genomic, and signature features in a curated and harmonized prostate cancer data resource. Biorxiv : the Preprint Server For Biology. PMID 36711769 DOI: 10.1101/2023.01.17.524403  0.307
2020 Stopsack KH, Huang Y, Tyekucheva S, Gerke TA, Bango C, Elfandy H, Bowden M, Penney KL, Roberts TM, Parmigiani G, Kantoff PW, Mucci LA, Loda M. Multiplex immunofluorescence in formalin-fixed paraffin-embedded tumor tissue to identify single cell-level PI3K pathway activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32913135 DOI: 10.1158/1078-0432.Ccr-20-2000  0.302
2020 Stover EH, Tyekucheva S, Liu Y, Curtis JD, Penson RT, Liu JF. Abstract 1048: Genomic analysis of patients with relapsed ovarian cancer enrolled in a phase II trial of nivolumab and bevacizumab Cancer Research. 80: 1048-1048. DOI: 10.1158/1538-7445.Am2020-1048  0.427
2019 Stopsack KH, Gerke T, Tyekucheva S, Mazzu YZ, Lee GM, Chakraborty G, Abida W, Mucci LA, Kantoff PW. Low expression of the androgen-induced tumor suppressor gene PLZF and lethal prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30602500 DOI: 10.1158/1055-9965.Epi-18-1014  0.362
2019 Laajala TD, Gerke T, Tyekucheva S, Costello JC. Modeling genetic heterogeneity of drug response and resistance in cancer Current Opinion in Systems Biology. 17: 8-14. DOI: 10.1016/J.Coisb.2019.09.003  0.309
2018 Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, et al. Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30578319 DOI: 10.1073/Pnas.1808834116  0.312
2018 Wang Z, Cao S, Morris JS, Ahn J, Liu R, Tyekucheva S, Gao F, Li B, Lu W, Tang X, Wistuba II, Bowden M, Mucci L, Loda M, Parmigiani G, et al. Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration. Iscience. 9: 451-460. PMID 30469014 DOI: 10.1016/J.Isci.2018.10.028  0.335
2018 Elfandy H, Armenia J, Pederzoli F, Pullman E, Pértega-Gomes N, Schultz N, Viswanathan K, Vosoughi A, Blattner M, Stopsack KH, Zadra G, Penney KL, Mosquera JM, Tyekucheva S, Mucci LA, et al. Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate. Molecular Cancer Research : McR. PMID 30333152 DOI: 10.1158/1541-7786.Mcr-18-0440  0.405
2018 Stopsack KH, Gerke TA, Tyekucheva S, Mucci LA, Kantoff PW. Regulation of the tumor suppressor PLZF and prostate cancer prognosis. Journal of Clinical Oncology. 36: 137-137. DOI: 10.1200/Jco.2018.36.6_Suppl.137  0.383
2018 Gerke T, Tyekucheva S, Creed JH, Penney KL, Sinnott JA, Ebot E, Berglund AE, Loda M, Stampfer MJ, Kraft P, Parmigiani G, Mucci LA. Abstract A045: All happy families are alike: Transcriptomic homogeneity in indolent prostate tumors is a useful prognostic biomarker Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-A045  0.39
2017 Pettersson A, Gerke T, Penney KL, Lis RT, Stack EC, Pértega-Gomes N, Zadra G, Tyekucheva S, Giovannucci EL, Mucci LA, Loda M. MYC overexpression at the protein and mRNA level and cancer outcomes among men treated with radical prostatectomy for prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 29141848 DOI: 10.1158/1055-9965.Epi-17-0637  0.322
2017 Tyekucheva S, Bowden M, Bango C, Giunchi F, Huang Y, Zhou C, Bondi A, Lis R, Van Hemelrijck M, Andrén O, Andersson SO, Watson RW, Pennington S, Finn SP, Martin NE, et al. Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer. Nature Communications. 8: 420. PMID 28871082 DOI: 10.1038/S41467-017-00460-4  0.377
2017 Ebot EM, Gerke T, Labbé DP, Sinnott JA, Zadra G, Rider JR, Tyekucheva S, Wilson KM, Kelly RS, Shui IM, Loda M, Kantoff PW, Finn S, Vander Heiden MG, Brown M, et al. Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer. Cancer. PMID 28700821 DOI: 10.1002/Cncr.30831  0.342
2017 Cacciatore S, Zadra G, Bango C, Penney KL, Tyekucheva S, Yanes O, Loda M. Metabolic Profiling in Formalin-Fixed and Paraffin Embedded Prostate Cancer Tissues. Molecular Cancer Research : McR. PMID 28074002 DOI: 10.1158/1541-7786.Mcr-16-0262  0.327
2017 Gerke T, Börnigen D, Beltran H, Tyekucheva S, Huttenhower C, Lee G, Trock B, Mucci L, Sweeney C. Abstract 4740: Loss of the tumor suppressor zinc finger protein-36 and risk of lethal prostate cancer Cancer Research. 77: 4740-4740. DOI: 10.1158/1538-7445.Am2017-4740  0.382
2017 Ebot E, Isikbay M, Gerke T, Ahearn TU, Kelly RS, Tyekucheva S, Pettersson A, Penney KL, Mucci LA. Abstract 4236: Gene expression profiling of prostate tissue identifies biological pathways associated withTMPRSS2:ERGgene fusion Epidemiology. 77: 4236-4236. DOI: 10.1158/1538-7445.Am2017-4236  0.339
2016 Kelly RS, Sinnott JA, Rider JR, Ebot EM, Gerke T, Bowden M, Pettersson A, Loda M, Sesso HD, Kantoff PW, Martin NE, Giovannucci EL, Tyekucheva S, Heiden MV, Mucci LA. The role of tumor metabolism as a driver of prostate cancer progression and lethal disease: results from a nested case-control study. Cancer & Metabolism. 4: 22. PMID 27980733 DOI: 10.1186/S40170-016-0161-9  0.316
2016 Sinnott JA, Peisch S, Tyekucheva S, Gerke TA, Lis RT, Rider JR, Fiorentino M, Stampfer MJ, Mucci LA, Loda M, Penney KL. Prognostic Utility of a New mRNA Expression Signature of Gleason Score. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663590 DOI: 10.1158/1078-0432.Ccr-16-1245  0.327
2016 Stopsack KH, Gerke TA, Sinnott JA, Penney KL, Tyekucheva S, Sesso HD, Andersson SO, Andrén O, Cerhan JR, Giovannucci EL, Mucci LA, Rider JR. Cholesterol metabolism and prostate cancer lethality. Cancer Research. PMID 27325648 DOI: 10.1158/0008-5472.Can-16-0903  0.36
2016 Börnigen D, Tyekucheva S, Wang X, Rider JR, Lee GS, Mucci LA, Sweeney C, Huttenhower C. Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer. Plos Computational Biology. 12: e1004820. PMID 27078000 DOI: 10.1371/Journal.Pcbi.1004820  0.376
2016 Ebot EM, Gerke T, Tyekucheva S, Labbé DP, Zadra G, Kelly RS, Bowden M, Rider JR, Wilson MK, Martin NE, Brown M, Heiden MGV, Giovannucci EL, Loda M, Mucci LA. Abstract B67: Identifying obesity-linked gene expression changes in prostate cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B67  0.378
2016 Kelly RS, Sinnott JA, Rider JR, Ebot E, Gerke T, Penney KL, Bowden M, Pettersson A, Loda M, Stampfer M, Kantoff P, Martin NE, Giovannucci EL, Tyekucheva S, Heiden MV, et al. Abstract A25: Tumor metabolism as a driver of lethal prostate cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A25  0.374
2016 Penney K, Tyekucheva S, Loda M. Abstract 6: Metabolomics of Gleason score in prostate tumor tissue and serum Cancer Research. 76: 6-6. DOI: 10.1158/1538-7445.Am2016-6  0.356
2016 Pértega-Gomes N, Tyekucheva S, Penney K, Zadra G, Mucci LA, Loda M. Abstract 4952: Co-expression of pAKT and MYC is associated with aggressive disease in human prostate cancer Cancer Research. 76: 4952-4952. DOI: 10.1158/1538-7445.Am2016-4952  0.397
2015 Lu D, Sinnott JA, Valdimarsdottir UA, Fang F, Gerke T, Tyekucheva S, Fiorentino M, Lambe M, Sesso HD, Sweeney CJ, Wilson KM, Giovannucci EL, Loda M, Mucci LA, Fall K. Stress-Related Signaling Pathways in Lethal and Non-Lethal Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26490316 DOI: 10.1158/1078-0432.Ccr-15-0101  0.352
2015 Tyekucheva S, Martin NE, Stack EC, Wei W, Vathipadiekal V, Waldron L, Fiorentino M, Lis RT, Stampfer MJ, Loda M, Parmigiani G, Mucci LA, Birrer M. Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues. The Journal of Molecular Diagnostics : Jmd. 17: 374-81. PMID 25937617 DOI: 10.1016/J.Jmoldx.2015.02.002  0.352
2015 Sinnott JA, Rider JR, Carlsson J, Gerke T, Tyekucheva S, Penney KL, Sesso HD, Loda M, Fall K, Stampfer MJ, Mucci LA, Pawitan Y, Andersson SO, Andrén O. Molecular differences in transition zone and peripheral zone prostate tumors. Carcinogenesis. 36: 632-8. PMID 25870172 DOI: 10.1093/Carcin/Bgv051  0.333
2015 Penney KL, Sinnott JA, Tyekucheva S, Gerke T, Shui IM, Kraft P, Sesso HD, Freedman ML, Loda M, Mucci LA, Stampfer MJ. Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 255-60. PMID 25371445 DOI: 10.1158/1055-9965.Epi-14-0694-T  0.383
2015 Gerke T, Tyekucheva S, Penney K, Sweeney C, Lis R, Sesso HD, Nuttall E, Loda M, Stampfer MJ, Parmigiani G, Mucci LA. Discovery and validation of a 30-gene expression signature to identify prostate cancer patients who are candidates for active surveillance. Journal of Clinical Oncology. 33: 10-10. DOI: 10.1200/Jco.2015.33.7_Suppl.10  0.376
2015 Kelly RS, Sinnott JA, Rider JR, Ebot E, Gerke T, Penney K, Bowden M, Loda M, Kantoff PW, Martin NE, Giovannucci EL, Pettersson AP, Tyekucheva S, Wilson KM, Heiden MV, et al. Abstract 5168: Tumor metabolism as a driver of lethal prostate cancer Cancer Research. 75: 5168-5168. DOI: 10.1158/1538-7445.Am2015-5168  0.359
2015 Ebot EM, Gerke T, Tyekucheva S, Labbé DP, Zadra G, Kelly RS, Bowden M, Rider JR, Wilson KM, Martin NE, Brown M, Heiden MGV, Giovannucci EL, Loda M, Mucci LA. Abstract 4686: Identifying obesity-linked gene expression changes in prostate cancer Cancer Research. 75: 4686-4686. DOI: 10.1158/1538-7445.Am2015-4686  0.36
2014 Waldron L, Haibe-Kains B, Culhane AC, Riester M, Ding J, Wang XV, Ahmadifar M, Tyekucheva S, Bernau C, Risch T, Ganzfried BF, Huttenhower C, Birrer M, Parmigiani G. Comparative meta-analysis of prognostic gene signatures for late-stage ovarian cancer. Journal of the National Cancer Institute. 106. PMID 24700801 DOI: 10.1093/Jnci/Dju049  0.336
2014 Zadra G, Photopoulos C, Tyekucheva S, Heidari P, Weng QP, Fedele G, Liu H, Scaglia N, Priolo C, Sicinska E, Mahmood U, Signoretti S, Birnberg N, Loda M. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. Embo Molecular Medicine. 6: 519-38. PMID 24497570 DOI: 10.1002/Emmm.201302734  0.308
2014 Gerke T, Tyekucheva S, Penney K, Sweeney C, Lis R, Nuttall I, Loda M, Stampfer M, Parmigiani G, Mucci L. Mp79-02 Discovery Of A Gene Expression Signature Of Prostate Cancer Prognostication By Focusing On Indolent Tumors The Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.2505  0.322
2013 Ganzfried BF, Riester M, Haibe-Kains B, Risch T, Tyekucheva S, Jazic I, Wang XV, Ahmadifar M, Birrer MJ, Parmigiani G, Huttenhower C, Waldron L. curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome. Database : the Journal of Biological Databases and Curation. 2013: bat013. PMID 23550061 DOI: 10.1093/Database/Bat013  0.345
2013 Li Q, Seo JH, Stranger B, McKenna A, Pe'er I, Laframboise T, Brown M, Tyekucheva S, Freedman ML. Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell. 152: 633-41. PMID 23374354 DOI: 10.1016/J.Cell.2012.12.034  0.356
2011 Tyekucheva S, Marchionni L, Karchin R, Parmigiani G. Integrating diverse genomic data using gene sets. Genome Biology. 12: R105. PMID 22018358 DOI: 10.1186/Gb-2011-12-10-R105  0.383
2011 Tyekucheva S, Yolken RH, McCombie WR, Parla J, Kramer M, Wheelan SJ, Sabunciyan S. Establishing the baseline level of repetitive element expression in the human cortex. Bmc Genomics. 12: 495. PMID 21985647 DOI: 10.1186/1471-2164-12-495  0.333
2009 Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R. Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations Cancer Research. 69: 6660-6667. PMID 19654296 DOI: 10.1158/0008-5472.Can-09-1133  0.336
2008 Tyekucheva S, Makova KD, Karro JE, Hardison RC, Miller W, Chiaromonte F. Human-macaque comparisons illuminate variation in neutral substitution rates. Genome Biology. 9: R76. PMID 18447906 DOI: 10.1186/Gb-2008-9-4-R76  0.605
2008 Kelkar YD, Tyekucheva S, Chiaromonte F, Makova KD. The genome-wide determinants of human and chimpanzee microsatellite evolution. Genome Research. 18: 30-8. PMID 18032720 DOI: 10.1101/Gr.7113408  0.64
2008 Tyekucheva S, Chiaromonte F. Rejoinder on: Augmenting the bootstrap to analyze high dimensional genomic data Test. 17: 47-55. DOI: 10.1007/S11749-008-0107-9  0.61
2008 Tyekucheva S, Chiaromonte F. Augmenting the bootstrap to analyze high dimensional genomic data Test. 17: 1-18. DOI: 10.1007/S11749-008-0098-6  0.609
2007 Miller W, Rosenbloom K, Hardison RC, Hou M, Taylor J, Raney B, Burhans R, King DC, Baertsch R, Blankenberg D, Kosakovsky Pond SL, Nekrutenko A, Giardine B, Harris RS, Tyekucheva S, et al. 28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Research. 17: 1797-808. PMID 17984227 DOI: 10.1101/Gr.6761107  0.384
2007 Kvikstad EM, Tyekucheva S, Chiaromonte F, Makova KD. A macaque's-eye view of human insertions and deletions: differences in mechanisms. Plos Computational Biology. 3: 1772-82. PMID 17941704 DOI: 10.1371/Journal.Pcbi.0030176  0.64
2006 Taylor J, Tyekucheva S, King DC, Hardison RC, Miller W, Chiaromonte F. ESPERR: learning strong and weak signals in genomic sequence alignments to identify functional elements. Genome Research. 16: 1596-604. PMID 17053093 DOI: 10.1101/Gr.4537706  0.6
2006 Carrel L, Park C, Tyekucheva S, Dunn J, Chiaromonte F, Makova KD. Genomic environment predicts expression patterns on the human inactive X chromosome. Plos Genetics. 2: e151. PMID 17009873 DOI: 10.1371/Journal.Pgen.0020151  0.616
2006 Taylor J, Tyekucheva S, Zody M, Chiaromonte F, Makova KD. Strong and weak male mutation bias at different sites in the primate genomes: insights from the human-chimpanzee comparison. Molecular Biology and Evolution. 23: 565-73. PMID 16280537 DOI: 10.1093/Molbev/Msj060  0.589
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