| Year |
Citation |
Score |
| 2013 |
Roberts JK, Moore CD, Romero EG, Ward RM, Yost GS, Reilly CA. Regulation of CYP3A genes by glucocorticoids in human lung cells. F1000research. 2: 173. PMID 24555085 DOI: 10.12688/F1000Research.2-173.V2 |
0.394 |
|
| 2013 |
Roberts JK, Moore CD, Ward RM, Yost GS, Reilly CA. Metabolism of beclomethasone dipropionate by cytochrome P450 3A enzymes. The Journal of Pharmacology and Experimental Therapeutics. 345: 308-16. PMID 23512537 DOI: 10.1124/Jpet.112.202556 |
0.416 |
|
| 2013 |
Cruzan G, Bus J, Hotchkiss J, Sura R, Moore C, Yost G, Banton M, Sarang S. Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors. Regulatory Toxicology and Pharmacology : Rtp. 66: 24-9. PMID 23454103 DOI: 10.1016/J.Yrtph.2013.02.008 |
0.319 |
|
| 2013 |
Moore CD, Roberts JK, Orton CR, Murai T, Fidler TP, Reilly CA, Ward RM, Yost GS. Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 379-89. PMID 23143891 DOI: 10.1124/Dmd.112.046318 |
0.363 |
|
| 2013 |
Reilly CA, Henion F, Bugni TS, Ethirajan M, Stockmann C, Pramanik KC, Srivastava SK, Yost GS. Reactive intermediates produced from the metabolism of the vanilloid ring of capsaicinoids by p450 enzymes. Chemical Research in Toxicology. 26: 55-66. PMID 23088752 DOI: 10.1021/Tx300366K |
0.462 |
|
| 2012 |
Shahrokh K, Cheatham TE, Yost GS. Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen. Biochimica Et Biophysica Acta. 1820: 1605-17. PMID 22677141 DOI: 10.1016/J.Bbagen.2012.05.011 |
0.766 |
|
| 2012 |
Zhou X, D'Agostino J, Li L, Moore CD, Yost GS, Ding X. Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 642-7. PMID 22228748 DOI: 10.1124/Dmd.111.044081 |
0.43 |
|
| 2012 |
Deering-Rice CE, Johansen ME, Roberts JK, Thomas KC, Romero EG, Lee J, Yost GS, Veranth JM, Reilly CA. Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material. Molecular Pharmacology. 81: 411-9. PMID 22155782 DOI: 10.1124/Mol.111.076067 |
0.372 |
|
| 2012 |
Shahrokh K, Orendt A, Yost GS, Cheatham TE. Quantum mechanically derived AMBER-compatible heme parameters for various states of the cytochrome P450 catalytic cycle. Journal of Computational Chemistry. 33: 119-33. PMID 21997754 DOI: 10.1002/Jcc.21922 |
0.771 |
|
| 2012 |
Thomas KC, Roberts JK, Deering-Rice CE, Romero EG, Dull RO, Lee J, Yost GS, Reilly CA. Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L111-9. PMID 21949157 DOI: 10.1152/Ajplung.00231.2011 |
0.342 |
|
| 2011 |
Deering-Rice CE, Romero EG, Shapiro D, Hughen RW, Light AR, Yost GS, Veranth JM, Reilly CA. Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chemical Research in Toxicology. 24: 950-9. PMID 21591660 DOI: 10.1021/Tx200123Z |
0.346 |
|
| 2011 |
Thomas KC, Ethirajan M, Shahrokh K, Sun H, Lee J, Cheatham TE, Yost GS, Reilly CA. Structure-activity relationship of capsaicin analogs and transient receptor potential vanilloid 1-mediated human lung epithelial cell toxicity. The Journal of Pharmacology and Experimental Therapeutics. 337: 400-10. PMID 21343315 DOI: 10.1124/Jpet.110.178491 |
0.767 |
|
| 2010 |
Moore CD, Shahrokh K, Sontum SF, Cheatham TE, Yost GS. Improved cytochrome P450 3A4 molecular models accurately predict the Phe215 requirement for raloxifene dehydrogenation selectivity. Biochemistry. 49: 9011-9. PMID 20812728 DOI: 10.1021/Bi101139Q |
0.777 |
|
| 2010 |
Weems JM, Lamb JG, D'Agostino J, Ding X, Yost GS. Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK. Chemical Research in Toxicology. 23: 1682-90. PMID 20795680 DOI: 10.1021/Tx100147Z |
0.793 |
|
| 2010 |
Murai T, Reilly CA, Ward RM, Yost GS. The inhaled glucocorticoid fluticasone propionate efficiently inactivates cytochrome P450 3A5, a predominant lung P450 enzyme. Chemical Research in Toxicology. 23: 1356-64. PMID 20707410 DOI: 10.1021/Tx100124K |
0.421 |
|
| 2010 |
Moore CD, Reilly CA, Yost GS. CYP3A4-Mediated oxygenation versus dehydrogenation of raloxifene. Biochemistry. 49: 4466-75. PMID 20405834 DOI: 10.1021/Bi902213R |
0.369 |
|
| 2010 |
Weems JM, Yost GS. 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively. Chemical Research in Toxicology. 23: 696-704. PMID 20187624 DOI: 10.1021/Tx9004506 |
0.804 |
|
| 2009 |
Weems JM, Cutler NS, Moore C, Nichols WK, Martin D, Makin E, Lamb JG, Yost GS. 3-Methylindole is mutagenic and a possible pulmonary carcinogen. Toxicological Sciences : An Official Journal of the Society of Toxicology. 112: 59-67. PMID 19700606 DOI: 10.1093/Toxsci/Kfp201 |
0.773 |
|
| 2009 |
D'Agostino J, Zhuo X, Shadid M, Morgan DG, Zhang X, Humphreys WG, Shu YZ, Yost GS, Ding X. The pneumotoxin 3-methylindole is a substrate and a mechanism-based inactivator of CYP2A13, a human cytochrome P450 enzyme preferentially expressed in the respiratory tract Drug Metabolism and Disposition. 37: 2018-2027. PMID 19608696 DOI: 10.1124/Dmd.109.027300 |
0.429 |
|
| 2009 |
Sun H, Moore C, Dansette PM, Kumar S, Halpert JR, Yost GS. Dehydrogenation of the indoline-containing drug 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide (indapamide) by CYP3A4: correlation with in silico predictions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 672-84. PMID 19074530 DOI: 10.1124/Dmd.108.022707 |
0.433 |
|
| 2008 |
Kartha JS, Skordos KW, Sun H, Hall C, Easterwood LM, Reilly CA, Johnson EF, Yost GS. Single mutations change CYP2F3 from a dehydrogenase of 3-methylindole to an oxygenase. Biochemistry. 47: 9756-70. PMID 18717595 DOI: 10.1021/Bi8005658 |
0.722 |
|
| 2008 |
Sabnis AS, Shadid M, Yost GS, Reilly CA. Human lung epithelial cells express a functional cold-sensing TRPM8 variant. American Journal of Respiratory Cell and Molecular Biology. 39: 466-74. PMID 18458237 DOI: 10.1165/Rcmb.2007-0440Oc |
0.33 |
|
| 2008 |
Sabnis AS, Reilly CA, Veranth JM, Yost GS. Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L194-200. PMID 18441098 DOI: 10.1152/Ajplung.00072.2008 |
0.338 |
|
| 2008 |
Bogen KT, Benson JM, Yost GS, Morris JB, Dahl AR, Clewell HJ, Krishnan K, Omiecinski CJ. Naphthalene metabolism in relation to target tissue anatomy, physiology, cytotoxicity and tumorigenic mechanism of action. Regulatory Toxicology and Pharmacology : Rtp. 51: S27-36. PMID 18191315 DOI: 10.1016/J.Yrtph.2007.10.018 |
0.364 |
|
| 2008 |
Sun H, Yost GS. Metabolic activation of a novel 3-substituted indole-containing TNF-alpha inhibitor: dehydrogenation and inactivation of CYP3A4. Chemical Research in Toxicology. 21: 374-85. PMID 18095656 DOI: 10.1021/Tx700294G |
0.409 |
|
| 2008 |
Kartha JS, Yost GS. Mechanism-based inactivation of lung-selective cytochrome P450 CYP2F enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 155-62. PMID 17962375 DOI: 10.1124/Dmd.107.017897 |
0.743 |
|
| 2007 |
Biggs JS, Wan J, Cutler NS, Hakkola J, Uusimäki P, Raunio H, Yost GS. Transcription factor binding to a putative double E-box motif represses CYP3A4 expression in human lung cells. Molecular Pharmacology. 72: 514-25. PMID 17548528 DOI: 10.1124/Mol.106.033795 |
0.422 |
|
| 2007 |
Sun H, Ehlhardt WJ, Kulanthaivel P, Lanza DL, Reilly CA, Yost GS. Dehydrogenation of indoline by cytochrome P450 enzymes: a novel "aromatase" process. The Journal of Pharmacology and Experimental Therapeutics. 322: 843-51. PMID 17502430 DOI: 10.1124/Jpet.107.121723 |
0.38 |
|
| 2007 |
Thomas KC, Sabnis AS, Johansen ME, Lanza DL, Moos PJ, Yost GS, Reilly CA. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. The Journal of Pharmacology and Experimental Therapeutics. 321: 830-8. PMID 17332266 DOI: 10.1124/Jpet.107.119412 |
0.363 |
|
| 2007 |
Yan Z, Easterwood LM, Maher N, Torres R, Huebert N, Yost GS. Metabolism and bioactivation of 3-methylindole by human liver microsomes. Chemical Research in Toxicology. 20: 140-8. PMID 17226936 DOI: 10.1021/Tx060239E |
0.356 |
|
| 2006 |
Reilly CA, Yost GS. Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processes. Drug Metabolism Reviews. 38: 685-706. PMID 17145696 DOI: 10.1080/03602530600959557 |
0.436 |
|
| 2006 |
Genter MB, Yost GS, Rettie AE. Localization of CYP4B1 in the rat nasal cavity and analysis of CYPs as secreted proteins. Journal of Biochemical and Molecular Toxicology. 20: 139-41. PMID 16788951 DOI: 10.1002/Jbt.20123 |
0.318 |
|
| 2006 |
Du L, Neis MM, Ladd PA, Lanza DL, Yost GS, Keeney DS. Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells. Toxicology and Applied Pharmacology. 213: 135-44. PMID 16307767 DOI: 10.1016/J.Taap.2005.10.003 |
0.322 |
|
| 2006 |
Johansen ME, Reilly CA, Yost GS. TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 89: 278-86. PMID 16120755 DOI: 10.1093/Toxsci/Kfi292 |
0.337 |
|
| 2005 |
Reilly CA, Johansen ME, Lanza DL, Lee J, Lim JO, Yost GS. Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells. Journal of Biochemical and Molecular Toxicology. 19: 266-75. PMID 16173059 DOI: 10.1002/Jbt.20084 |
0.318 |
|
| 2005 |
Kassahun K, Skordos K, McIntosh I, Slaughter D, Doss GA, Baillie TA, Yost GS. Zafirlukast metabolism by cytochrome P450 3A4 produces an electrophilic alpha,beta-unsaturated iminium species that results in the selective mechanism-based inactivation of the enzyme. Chemical Research in Toxicology. 18: 1427-37. PMID 16167835 DOI: 10.1021/Tx050092B |
0.452 |
|
| 2005 |
Poch MT, Cutler NS, Yost GS, Hines RN. Molecular mechanisms regulating human CYP4B1 lung-selective expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1174-84. PMID 15900016 DOI: 10.1124/Dmd.105.004523 |
0.368 |
|
| 2005 |
Wan J, Carr BA, Cutler NS, Lanza DL, Hines RN, Yost GS. Sp1 and Sp3 regulate basal transcription of the human CYP2F1 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1244-53. PMID 15860659 DOI: 10.1124/Dmd.105.004069 |
0.673 |
|
| 2005 |
Reilly CA, Yost GS. Structural and enzymatic parameters that determine alkyl dehydrogenation/hydroxylation of capsaicinoids by cytochrome p450 enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 530-6. PMID 15640380 DOI: 10.1124/Dmd.104.001214 |
0.434 |
|
| 2004 |
Simmonds AC, Ghanayem BI, Sharma A, Reilly CA, Millen B, Yost GS, Forkert PG. Bioactivation of 1,1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung. The Journal of Pharmacology and Experimental Therapeutics. 310: 855-64. PMID 15123768 DOI: 10.1124/Jpet.104.068171 |
0.4 |
|
| 2004 |
Sheets PL, Yost GS, Carlson GP. Benzene metabolism in human lung cell lines BEAS-2B and A549 and cells overexpressing CYP2F1. Journal of Biochemical and Molecular Toxicology. 18: 92-9. PMID 15122651 DOI: 10.1002/Jbt.20010 |
0.484 |
|
| 2003 |
Reilly CA, Taylor JL, Lanza DL, Carr BA, Crouch DJ, Yost GS. Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 170-81. PMID 12721390 DOI: 10.1093/Toxsci/Kfg044 |
0.681 |
|
| 2003 |
Carr BA, Ramakanth S, Dannan GA, Yost GS. Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole. Molecular Pharmacology. 63: 1137-47. PMID 12695542 DOI: 10.1124/Mol.63.5.1137 |
0.747 |
|
| 2003 |
Reilly CA, Ehlhardt WJ, Jackson DA, Kulanthaivel P, Mutlib AE, Espina RJ, Moody DE, Crouch DJ, Yost GS. Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells. Chemical Research in Toxicology. 16: 336-49. PMID 12641434 DOI: 10.1021/Tx025599Q |
0.421 |
|
| 2003 |
Carr BA, Wan J, Hines RN, Yost GS. Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif. The Journal of Biological Chemistry. 278: 15473-83. PMID 12598524 DOI: 10.1074/Jbc.M300319200 |
0.693 |
|
| 2003 |
Nichols WK, Mehta R, Skordos K, Macé K, Pfeifer AM, Carr BA, Minko T, Burchiel SW, Yost GS. 3-methylindole-induced toxicity to human bronchial epithelial cell lines. Toxicological Sciences : An Official Journal of the Society of Toxicology. 71: 229-36. PMID 12563108 DOI: 10.1093/Toxsci/71.2.229 |
0.691 |
|
| 2001 |
Yost GS. Bioactivation of toxicants by cytochrome P450-mediated dehydrogenation mechanisms Advances in Experimental Medicine and Biology. 500: 53-62. PMID 11764993 DOI: 10.1007/978-1-4615-0667-6_6 |
0.353 |
|
| 2001 |
Regal KA, Laws GM, Yuan C, Yost GS, Skiles GL. Detection and characterization of DNA adducts of 3-methylindole Chemical Research in Toxicology. 14: 1014-1024. PMID 11511175 DOI: 10.1021/Tx0100237 |
0.357 |
|
| 2001 |
Lanza DL, Yost GS. Selective dehydrogenation/oxygenation of 3-methylindole by cytochrome P450 enzymes Drug Metabolism and Disposition. 29: 950-953. PMID 11408359 |
0.373 |
|
| 1999 |
Lanza DL, Code E, Crespi CL, Gonzalez FJ, Yost GS. Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells Drug Metabolism and Disposition. 27: 798-803. PMID 10383923 |
0.386 |
|
| 1998 |
Skordos KW, Laycock JD, Yost GS. Thioether adducts of a new imine reactive intermediate of the pneumotoxin 3-methylindole Chemical Research in Toxicology. 11: 1326-1331. PMID 9815193 DOI: 10.1021/Tx9801209 |
0.383 |
|
| 1998 |
Skordos KW, Skiles GL, Laycock JD, Lanza DL, Yost GS. Evidence supporting the formation of 2,3-epoxy-3-methylindoline: A reactive intermediate of the pneumotoxin 3-methylindole Chemical Research in Toxicology. 11: 741-749. PMID 9671536 DOI: 10.1021/Tx9702087 |
0.39 |
|
| 1998 |
Wang H, Lanza DL, Yost GS. Cloning and expression of CYP2F3, a cytochrome P450 that bioactivates the selective pneumotoxins 3-methylindole and naphthalene Archives of Biochemistry and Biophysics. 349: 329-340. PMID 9448722 DOI: 10.1006/Abbi.1997.0479 |
0.488 |
|
| 1997 |
Kaster JK, Yost GS. Production and characterization of specific antibodies: Utilization to predict organ- and species-selective pneumotoxicity of 3-methylindole Toxicology and Applied Pharmacology. 143: 324-337. PMID 9144449 DOI: 10.1006/Taap.1996.8092 |
0.398 |
|
| 1996 |
Skiles GL, Yost GS. Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole Chemical Research in Toxicology. 9: 291-297. PMID 8924606 DOI: 10.1021/Tx9501187 |
0.44 |
|
| 1996 |
Yost GS. Mechanisms of cytochrome P450-mediated formation of pneumotoxic electrophiles Advances in Experimental Medicine and Biology. 387: 221-229. PMID 8794216 DOI: 10.1007/978-1-4757-9480-9_30 |
0.47 |
|
| 1996 |
Thornton-Manning J, Appleton ML, Gonzalez FJ, Yost GS. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: Correlation of 3-methyleneindolenine formation and protein-binding Journal of Pharmacology and Experimental Therapeutics. 276: 21-29. PMID 8558432 |
0.387 |
|
| 1995 |
Nichols WK, Terry CM, Cutler NS, Appleton ML, Jesthi PK, Yost GS. Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p-chlorophenyl)ethane by rabbit and human lung cells. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 23: 595-9. PMID 7587937 |
0.307 |
|
| 1994 |
Ramakanth S, Thornton-Manning JR, Huifen W, Maxwell H, Yost GS. Correlation between pulmonary cytochrome P450 transcripts and the organ-selective pneumotoxicity of 3-methylindole Toxicology Letters. 71: 77-85. PMID 8140592 DOI: 10.1016/0378-4274(94)90201-1 |
0.361 |
|
| 1993 |
Smith DJ, Skiles GL, Appleton ML, Carlson JR, Yost GS. Identification of goat and mouse urinary metabolites of the pneumotoxin, 3-methylindole Xenobiotica. 23: 1025-1044. PMID 8291262 DOI: 10.3109/00498259309057041 |
0.305 |
|
| 1993 |
Thorntonmanning JR, Nichols WK, Manning BW, Skiles GL, Yost GS. Metabolism and Bioactivation of 3-Methylindole by Clara Cells, Alveolar Macrophages, and Subcellular Fractions from Rabbit Lungs Toxicology and Applied Pharmacology. 122: 182-190. PMID 8212000 DOI: 10.1006/Taap.1993.1186 |
0.465 |
|
| 1992 |
Nichols WK, Covington MO, Seiders CD, Safiullah S, Yost GS. Bioactivation of halogenated hydrocarbons by rabbit pulmonary cells Pharmacology and Toxicology. 71: 335-339. PMID 1448445 DOI: 10.1111/J.1600-0773.1992.Tb00557.X |
0.354 |
|
| 1992 |
Ruangyuttikarn W, Skiles GL, Yost GS. Identification of a cysteinyl adduct of oxidized 3-methylindole from goat lung and human liver microsomal proteins Chemical Research in Toxicology. 5: 713-719. PMID 1446013 DOI: 10.1021/Tx00029A019 |
0.387 |
|
| 1991 |
Appleton ML, Larson DN, Skiles GL, Nichols WK, Yost GS. Toxicity of 3-methyleneoxindole, a proposed reactive intermediate in the metabolism of 3-methylindole Advances in Experimental Medicine and Biology. 283: 245-248. PMID 2068989 DOI: 10.1007/978-1-4684-5877-0_24 |
0.408 |
|
| 1991 |
Skiles GL, Smith DJ, Appleton ML, Carlson JR, Yost GS. Isolation of a mercapturate adduct produced subsequent to glutathione conjugation of bioactivated 3-methylindole Toxicology and Applied Pharmacology. 108: 531-537. PMID 2020974 DOI: 10.1016/0041-008X(91)90099-Z |
0.345 |
|
| 1991 |
Thornton-Manning JR, Ruangyuttikarn W, Gonzalez FJ, Yost GS. Metabolic activation of the pneumotoxin, 3-methylindole, by vaccinia-expressed cytochrome P450s Biochemical and Biophysical Research Communications. 181: 100-107. PMID 1958177 DOI: 10.1016/S0006-291X(05)81387-7 |
0.467 |
|
| 1990 |
Yost GS, Kuntz DJ, McGill LD. Organ-selective switching of 3-methylindole toxicity by glutathione depletion. Toxicology and Applied Pharmacology. 103: 40-51. PMID 2315931 DOI: 10.1016/0041-008X(90)90260-2 |
0.302 |
|
| 1990 |
Nichols WK, Larson DN, Yost GS. Bioactivation of 3-methylindole by isolated rabbit lung cells Toxicology and Applied Pharmacology. 105: 264-270. PMID 2219119 DOI: 10.1016/0041-008X(90)90188-Z |
0.398 |
|
| 1989 |
Huijzer JC, Adams JD, Jaw JY, Yost GS. Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and α-methylbenzylaminobenzotriazole Drug Metabolism and Disposition. 17: 37-42. PMID 2566467 |
0.356 |
|
| 1989 |
Skiles GL, Adams JD, Yost GS. Isolation and identification of 3-hydroxy-3-methyloxindole, the major murine metabolite of 3-methylindole Chemical Research in Toxicology. 2: 254-259. PMID 2519781 DOI: 10.1021/Tx00010A007 |
0.373 |
|
| 1985 |
Nocerini MR, Carlson JR, Yost GS. Glutathione adduct formation with microsomally activated metabolites of the pulmonary alkylating and cytotoxic agent, 3-methylindole Toxicology and Applied Pharmacology. 81: 75-84. PMID 4049423 DOI: 10.1016/0041-008X(85)90122-X |
0.353 |
|
| 1979 |
Ortiz De Montellano PR, Kunze KL, Yost GS, Mico BA. Self-catalyzed destruction of cytochrome P-450: Covalent binding of ethynyl sterols to prosthetic heme Proceedings of the National Academy of Sciences of the United States of America. 76: 746-749. PMID 284396 DOI: 10.1073/pnas.76.2.746 |
0.69 |
|
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