| Year |
Citation |
Score |
| 2023 |
Kato M, Chen Z, Das S, Wu X, Wang J, Li A, Chen W, Tsark W, Tunduguru R, Lanting L, Wang M, Moore R, Kalkum M, Abdollahi M, Natarajan R. Long non-coding RNA lncMGC mediates the expression of TGF-β-induced genes in renal cells via nucleosome remodelers. Frontiers in Molecular Biosciences. 10: 1204124. PMID 37325470 DOI: 10.3389/fmolb.2023.1204124 |
0.742 |
|
| 2023 |
Tanwar VS, Reddy MA, Das S, Samara VA, Abdollahi M, Dey S, Malek V, Ganguly R, Stapleton K, Lanting L, Pirrotte P, Natarajan R. Palmitic Acid-Induced Long Noncoding RNA Regulates Inflammation via Interaction With RNA-Binding Protein ELAVL1 (ELAV Like RNA-Binding Protein 1) in Monocytes and Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37128912 DOI: 10.1161/ATVBAHA.122.318536 |
0.719 |
|
| 2022 |
Tang X, Luo Y, Yuan D, Calandrelli R, Malhi NK, Sriram K, Miao Y, Lou CH, Tsark W, Tapia A, Chen AT, Zhang G, Roeth D, Kalkum M, Wang ZV, ... ... Natarajan R, et al. Long non-coding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models. The Journal of Clinical Investigation. PMID 36512424 DOI: 10.1172/JCI161759 |
0.401 |
|
| 2022 |
Sriram K, Luo Y, Yuan D, Malhi NK, Tapia A, Samara VA, Natarajan R, Bouman Chen Z. Vascular Regulation by Super Enhancer-Derived LINC00607. Frontiers in Cardiovascular Medicine. 9: 881916. PMID 35837599 DOI: 10.3389/fcvm.2022.881916 |
0.391 |
|
| 2022 |
Chen Z, Natarajan R. Epigenetic modifications in metabolic memory: What are the memories, and can we erase them? American Journal of Physiology. Cell Physiology. PMID 35785987 DOI: 10.1152/ajpcell.00201.2022 |
0.353 |
|
| 2021 |
Samara VA, Das S, Reddy MA, Tanwar VS, Stapleton K, Leung A, Abdollahi M, Ganguly R, Lanting L, Natarajan R. Angiotensin II-Induced Long Non-Coding RNA Regulates Chondrogenesis in Vascular Smooth Muscle Cells. Cells. 10. PMID 34685676 DOI: 10.3390/cells10102696 |
0.739 |
|
| 2021 |
Tanwar VS, Reddy MA, Natarajan R. Emerging Role of Long Non-Coding RNAs in Diabetic Vascular Complications. Frontiers in Endocrinology. 12: 665811. PMID 34234740 DOI: 10.3389/fendo.2021.665811 |
0.418 |
|
| 2021 |
Reddy MA, Amaram V, Das S, Tanwar VS, Ganguly R, Wang M, Lanting L, Zhang L, Abdollahi M, Chen Z, Wu X, Devaraj S, Natarajan R. LncRNA DRAIR is downregulated in diabetic monocytes and modulates inflammatory phenotype via epigenetic mechanisms. Jci Insight. PMID 33945509 DOI: 10.1172/jci.insight.143289 |
0.76 |
|
| 2021 |
Natarajan R. Epigenetic Mechanisms in Diabetic Vascular Complications and Metabolic Memory: The 2020 Edwin Bierman Award Lecture. Diabetes. 70: 328-337. PMID 33472942 DOI: 10.2337/dbi20-0030 |
0.417 |
|
| 2020 |
Das S, Natarajan R. HDAC9: An Inflammatory Link in Atherosclerosis. Circulation Research. 127: 824-826. PMID 32853095 DOI: 10.1161/Circresaha.120.317723 |
0.707 |
|
| 2020 |
Bansal A, Balasubramanian S, Dhawan S, Leung A, Chen Z, Natarajan R. Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction. Diabetes. PMID 32747424 DOI: 10.2337/Db20-0382 |
0.483 |
|
| 2020 |
Chen Z, Miao F, Braffett BH, Lachin JM, Zhang L, Wu X, Roshandel D, Carless M, Li XA, Tompkins JD, Kaddis JS, Riggs AD, Paterson AD, Natarajan R. DNA methylation mediates development of HbA1c-associated complications in type 1 diabetes. Nature Metabolism. PMID 32694834 DOI: 10.1038/s42255-020-0231-8 |
0.351 |
|
| 2020 |
Tang X, Miao Y, Luo Y, Sriram K, Qi Z, Lin FM, Gu Y, Lai CH, Hsu CY, Peterson KL, Van Keuren-Jensen K, Fueger PT, Yeo GW, Natarajan R, Zhong S, et al. Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction. Circulation. PMID 32393053 DOI: 10.1161/Circulationaha.119.041231 |
0.389 |
|
| 2020 |
Roshandel D, Chen Z, Canty AJ, Bull SB, Natarajan R, Paterson AD. DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes. Clinical Epigenetics. 12: 52. PMID 32248841 DOI: 10.1186/S13148-020-00840-6 |
0.392 |
|
| 2020 |
Das S, Reddy MA, Natarajan R. Role of epigenetic mechanisms regulated by enhancers and long noncoding RNAs in cardiovascular disease. Current Opinion in Cardiology. PMID 32205477 DOI: 10.1097/Hco.0000000000000728 |
0.754 |
|
| 2020 |
Stapleton K, Das S, Reddy MA, Leung A, Amaram V, Lanting L, Chen Z, Zhang L, Palanivel R, Deiuliis JA, Natarajan R. Novel Long Noncoding RNA, Macrophage Inflammation-Suppressing Transcript (), Regulates Macrophage Activation During Obesity. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313359. PMID 32078363 DOI: 10.1161/Atvbaha.119.313359 |
0.74 |
|
| 2020 |
Tanwar VS, Reddy MA, Das S, Amaram V, Ganguly R, Stapleton K, Lanting L, Natarajan R. Palmitic acid induced lncRNA PARAIL regulates inflammation in human monocytes and macrophages The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06582 |
0.715 |
|
| 2020 |
Reddy MA, Amaram V, Das S, Tanwar VS, Ganguly R, Wang M, Lanting L, Zhang L, Wu X, Devaraj S, Natarajan R. Epigenetic Mechanisms Involved in Anti‐Inflammatory Actions of a Diabetes Regulated lncRNA DRAIR in Monocytes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04829 |
0.774 |
|
| 2019 |
Jia Y, Reddy MA, Das S, Oh HJ, Abdollahi M, Yuan H, Zhang E, Lanting L, Wang M, Natarajan R. Dysregulation of histone H3 lysine 27 trimethylation in transforming growth factor-β1 induced gene expression in mesangial cells and diabetic kidney. The Journal of Biological Chemistry. PMID 31266808 DOI: 10.1074/Jbc.Ra119.007575 |
0.753 |
|
| 2019 |
Dhawan S, Natarajan R. Epigenetics and Type 2 Diabetes Risk. Current Diabetes Reports. 19: 47. PMID 31250127 DOI: 10.1007/S11892-019-1168-8 |
0.409 |
|
| 2019 |
Kato M, Natarajan R. Epigenetics and epigenomics in diabetic kidney disease and metabolic memory. Nature Reviews. Nephrology. PMID 30894700 DOI: 10.1038/S41581-019-0135-6 |
0.491 |
|
| 2019 |
Xu L, Natarajan R, Chen Z. Epigenetic Risk Profile of Diabetic Kidney Disease in High-Risk Populations. Current Diabetes Reports. 19: 9. PMID 30730019 DOI: 10.1007/S11892-019-1129-2 |
0.458 |
|
| 2019 |
ABDOLLAHI M, KATO M, TUNDUGURU R, LANTING LL, NATARAJAN R. 491-P: Obesity-Induced Kidney Damage Is Attenuated by Genetic Deletion of miR-379 in Mice Diabetes. 68: 491-P. DOI: 10.2337/Db19-491-P |
0.366 |
|
| 2019 |
TUNDUGURU R, KATO M, ABDOLLAHI M, LANTING LL, NATARAJAN R. 1929-P: Role of miR379 in Promoting Skeletal Muscle Atrophy in Type 1 Diabetes (T1D) Diabetes. 68: 1929-P. DOI: 10.2337/Db19-1929-P |
0.434 |
|
| 2018 |
Das S, Zhang E, Senapati P, Amaram V, Reddy MA, Stapleton K, Leung A, Lanting L, Wang M, Chen Z, Kato M, Oh HJ, Guo Q, Zhang X, Zhang B, ... ... Natarajan R, et al. A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Circulation Research. 123: 1298-1312. PMID 30566058 DOI: 10.1161/Circresaha.118.313207 |
0.787 |
|
| 2018 |
Rosen ED, Kaestner KH, Natarajan R, Patti ME, Sallari R, Sander M, Susztak K. Epigenetics and Epigenomics: Implications for Diabetes and Obesity. Diabetes. 67: 1923-1931. PMID 30237160 DOI: 10.2337/Db18-0537 |
0.461 |
|
| 2018 |
Das S, Reddy MA, Senapati P, Stapleton K, Lanting L, Wang M, Amaram V, Ganguly R, Zhang L, Devaraj S, Schones DE, Natarajan R. Diabetes Mellitus-Induced Long Noncoding RNA Regulates Macrophage Functions and Inflammation via Nuclear Mechanisms. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29930005 DOI: 10.1161/Atvbaha.117.310663 |
0.821 |
|
| 2018 |
Deshpande S, Abdollahi M, Wang M, Lanting L, Kato M, Natarajan R. Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy. Scientific Reports. 8: 6954. PMID 29725042 DOI: 10.1038/S41598-018-25295-X |
0.671 |
|
| 2018 |
Leung A, Amaram V, Natarajan R. Linking diabetic vascular complications with LncRNAs. Vascular Pharmacology. PMID 29398367 DOI: 10.1016/J.Vph.2018.01.007 |
0.493 |
|
| 2018 |
Ganguly R, Reddy MA, Chen Z, Amaram V, Bansal A, Lanting L, Natarajan R. Abstract 089: Role of LncRNA
Snhg18
in Diabetes Induced Macrophage Dysfunction and Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.089 |
0.471 |
|
| 2017 |
Gangwar RS, Rajagopalan S, Natarajan R, Deiuliis JA. Non-coding RNAs in cardiovascular disease: pathological relevance and emerging role as biomarkers and therapeutics. American Journal of Hypertension. PMID 29186297 DOI: 10.1093/Ajh/Hpx197 |
0.331 |
|
| 2017 |
Das S, Senapati P, Chen Z, Reddy MA, Ganguly R, Lanting L, Mandi V, Bansal A, Leung A, Zhang S, Jia Y, Wu X, Schones DE, Natarajan R. Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells. Nature Communications. 8: 1467. PMID 29133788 DOI: 10.1038/S41467-017-01629-7 |
0.804 |
|
| 2017 |
Leung A, Natarajan R. Long non-coding RNAs in diabetes and diabetic complications. Antioxidants & Redox Signaling. PMID 28934861 DOI: 10.1089/ars.2017.7315 |
0.388 |
|
| 2017 |
Oh HJ, Kato M, Deshpande S, Zhang E, Das S, Lanting L, Wang M, Natarajan R. Erratum: Inhibition of the processing of miR-25 by HIPK2-Phosphorylated-MeCP2 induces NOX4 in early diabetic nephropathy. Scientific Reports. 7: 40832. PMID 28112154 DOI: 10.1038/srep40832 |
0.786 |
|
| 2016 |
Oh HJ, Kato M, Deshpande S, Zhang E, Sadhan D, Lanting L, Wang M, Natarajan R. Inhibition of the processing of miR-25 by HIPK2-Phosphorylated-MeCP2 induces NOX4 in early diabetic nephropathy. Scientific Reports. 6: 38789. PMID 27941951 DOI: 10.1038/Srep38789 |
0.657 |
|
| 2016 |
Kato M, Wang M, Chen Z, Bhatt K, Oh HJ, Lanting L, Deshpande S, Jia Y, Lai JY, O'Connor CL, Wu Y, Hodgin JB, Nelson RG, Bitzer M, Natarajan R. An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy. Nature Communications. 7: 12864. PMID 27686049 DOI: 10.1038/Ncomms12864 |
0.674 |
|
| 2016 |
Grassi MA, Rao VR, Chen S, Cao D, Gao X, Cleary PA, Huang RS, Paterson AD, Natarajan R, Rehman J, Kern TS. Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose. Plos One. 11: e0160504. PMID 27509144 DOI: 10.1371/Journal.Pone.0160504 |
0.38 |
|
| 2016 |
Du J, Leung A, Trac C, Lee M, Parks BW, Lusis AJ, Natarajan R, Schones DE. Chromatin variation associated with liver metabolism is mediated by transposable elements. Epigenetics & Chromatin. 9: 28. PMID 27398095 DOI: 10.1186/S13072-016-0078-0 |
0.324 |
|
| 2016 |
Reddy MA, Natarajan R. Targeting miR-200c to Ameliorate Diabetes-Induced Endothelial Dysfunction. Diabetes. 65: 1152-4. PMID 27208183 DOI: 10.2337/Dbi16-0006 |
0.471 |
|
| 2016 |
Chen Z, Miao F, Paterson AD, Lachin JM, Zhang L, Schones DE, Wu X, Wang J, Tompkins JD, Genuth S, Braffett BH, Riggs AD, Natarajan R. Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162351 DOI: 10.1073/Pnas.1603712113 |
0.378 |
|
| 2016 |
Leung A, Trac C, Du J, Natarajan R, Schones DE. Persistent chromatin modifications induced by high fat diet. The Journal of Biological Chemistry. PMID 27006400 DOI: 10.1074/Jbc.M115.711028 |
0.331 |
|
| 2016 |
Reddy MA, Das S, Zhuo C, Jin W, Wang M, Lanting L, Natarajan R. Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26941017 DOI: 10.1161/Atvbaha.115.306770 |
0.778 |
|
| 2015 |
Bhatt K, Lanting LL, Jia Y, Yadav S, Reddy MA, Magilnick N, Boldin M, Natarajan R. Anti-Inflammatory Role of MicroRNA-146a in the Pathogenesis of Diabetic Nephropathy. Journal of the American Society of Nephrology : Jasn. PMID 26647423 DOI: 10.1681/Asn.2015010111 |
0.448 |
|
| 2015 |
Bhatt K, Kato M, Natarajan R. Emerging Roles of microRNAs in the Pathophysiology of Renal Diseases. American Journal of Physiology. Renal Physiology. ajprenal.00387.2015. PMID 26538441 DOI: 10.1152/Ajprenal.00387.2015 |
0.321 |
|
| 2015 |
Yuan H, Reddy M, Deshpande S, Jia Y, Park JT, Lanting L, Jin W, Kato M, Xu ZG, Das S, Natarajan R. Epigenetic Histone Modifications Involved in Pro-fibrotic Gene Regulation by 12/15-Lipoxygenase and its Oxidized Lipid Products in Diabetic Nephropathy. Antioxidants & Redox Signaling. PMID 26492974 DOI: 10.1089/Ars.2015.6372 |
0.807 |
|
| 2015 |
Schones DE, Leung A, Natarajan R. Chromatin Modifications Associated With Diabetes and Obesity. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1557-61. PMID 26044585 DOI: 10.1161/Atvbaha.115.305041 |
0.423 |
|
| 2015 |
Reddy MA, Natarajan R. Recent developments in epigenetics of acute and chronic kidney diseases. Kidney International. 88: 250-61. PMID 25993323 DOI: 10.1038/Ki.2015.148 |
0.386 |
|
| 2015 |
Leung A, Stapleton K, Natarajan R. Functional Long Non-coding RNAs in Vascular Smooth Muscle Cells. Current Topics in Microbiology and Immunology. PMID 25910717 DOI: 10.1007/82_2015_441 |
0.387 |
|
| 2015 |
Caramori ML, Kim Y, Natarajan R, Moore JH, Rich SS, Mychaleckyj JC, Kuriyama R, Kirkpatrick D, Mauer M. Differential Response to High Glucose in Skin Fibroblasts of Monozygotic Twins Discordant for Type 1 Diabetes. The Journal of Clinical Endocrinology and Metabolism. 100: E883-9. PMID 25901990 DOI: 10.1210/Jc.2014-4467 |
0.376 |
|
| 2015 |
Kato M, Natarajan R. MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets. Annals of the New York Academy of Sciences. PMID 25877817 DOI: 10.1111/Nyas.12758 |
0.442 |
|
| 2015 |
Reddy MA, Zhang E, Natarajan R. Epigenetic mechanisms in diabetic complications and metabolic memory. Diabetologia. 58: 443-55. PMID 25481708 DOI: 10.1007/S00125-014-3462-Y |
0.52 |
|
| 2014 |
Park JT, Kato M, Lanting L, Castro N, Nam BY, Wang M, Kang SW, Natarajan R. Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions. American Journal of Physiology. Renal Physiology. 307: F1390-403. PMID 25354942 DOI: 10.1152/Ajprenal.00458.2014 |
0.362 |
|
| 2014 |
Chen X, Zhang L, Zhang IY, Liang J, Wang H, Ouyang M, Wu S, da Fonseca AC, Weng L, Yamamoto Y, Yamamoto H, Natarajan R, Badie B. RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma. Cancer Research. 74: 7285-97. PMID 25326491 DOI: 10.1158/0008-5472.Can-14-1240 |
0.312 |
|
| 2014 |
Reddy MA, Chen Z, Park JT, Wang M, Lanting L, Zhang Q, Bhatt K, Leung A, Wu X, Putta S, Sætrom P, Devaraj S, Natarajan R. Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes. 63: 4249-61. PMID 25008173 DOI: 10.2337/Db14-0298 |
0.736 |
|
| 2014 |
Leung A, Parks BW, Du J, Trac C, Setten R, Chen Y, Brown K, Lusis AJ, Natarajan R, Schones DE. Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat diet. The Journal of Biological Chemistry. 289: 23557-67. PMID 25006255 DOI: 10.1074/Jbc.M114.581439 |
0.328 |
|
| 2014 |
Kato M, Natarajan R. Diabetic nephropathy--emerging epigenetic mechanisms. Nature Reviews. Nephrology. 10: 517-30. PMID 25003613 DOI: 10.1038/Nrneph.2014.116 |
0.501 |
|
| 2014 |
Leung A, Natarajan R. Noncoding RNAs in vascular disease. Current Opinion in Cardiology. 29: 199-206. PMID 24614861 DOI: 10.1097/Hco.0000000000000054 |
0.369 |
|
| 2014 |
Miao F, Chen Z, Genuth S, Paterson A, Zhang L, Wu X, Li SM, Cleary P, Riggs A, Harlan DM, Lorenzi G, Kolterman O, Sun W, Lachin JM, Natarajan R, et al. Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes. Diabetes. 63: 1748-62. PMID 24458354 DOI: 10.2337/Db13-1251 |
0.446 |
|
| 2014 |
Reddy MA, Sumanth P, Lanting L, Yuan H, Wang M, Mar D, Alpers CE, Bomsztyk K, Natarajan R. Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice. Kidney International. 85: 362-73. PMID 24088954 DOI: 10.1038/Ki.2013.387 |
0.517 |
|
| 2014 |
Chen X, Zhang L, Zhang I, Liang J, Weng L, Yamamoto Y, Yamamoto H, Natarajan R, Badie B. Ib-04Expression Of Rage By Tumor Macrophages Promotes Angiogenesis In Gliomas Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou257.4 |
0.302 |
|
| 2013 |
Leung A, Natarajan R. Forgetting to switch off SMAD2 in aneurysmal disease. Circulation Research. 113: 843-5. PMID 24030017 DOI: 10.1161/Circresaha.113.302138 |
0.367 |
|
| 2013 |
Reddy MA, Tak Park J, Natarajan R. Epigenetic modifications in the pathogenesis of diabetic nephropathy. Seminars in Nephrology. 33: 341-53. PMID 24011576 DOI: 10.1016/J.Semnephrol.2013.05.006 |
0.52 |
|
| 2013 |
Singhal SS, Figarola J, Singhal J, Reddy MA, Liu X, Berz D, Natarajan R, Awasthi S. RLIP76 protein knockdown attenuates obesity due to a high-fat diet. The Journal of Biological Chemistry. 288: 23394-406. PMID 23821548 DOI: 10.1074/Jbc.M113.480194 |
0.3 |
|
| 2013 |
Park JT, Kato M, Yuan H, Castro N, Lanting L, Wang M, Natarajan R. FOG2 protein down-regulation by transforming growth factor-β1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy. The Journal of Biological Chemistry. 288: 22469-80. PMID 23788640 DOI: 10.1074/Jbc.M113.453043 |
0.406 |
|
| 2013 |
Kato M, Castro NE, Natarajan R. MicroRNAs: potential mediators and biomarkers of diabetic complications. Free Radical Biology & Medicine. 64: 85-94. PMID 23770198 DOI: 10.1016/J.Freeradbiomed.2013.06.009 |
0.472 |
|
| 2013 |
Kato M, Dang V, Wang M, Park JT, Deshpande S, Kadam S, Mardiros A, Zhan Y, Oettgen P, Putta S, Yuan H, Lanting L, Natarajan R. TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy. Science Signaling. 6: ra43. PMID 23737551 DOI: 10.1126/Scisignal.2003389 |
0.769 |
|
| 2013 |
Leung A, Trac C, Jin W, Lanting L, Akbany A, Sætrom P, Schones DE, Natarajan R. Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells. Circulation Research. 113: 266-78. PMID 23697773 DOI: 10.1161/Circresaha.112.300849 |
0.341 |
|
| 2013 |
Deshpande SD, Putta S, Wang M, Lai JY, Bitzer M, Nelson RG, Lanting LL, Kato M, Natarajan R. Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy. Diabetes. 62: 3151-62. PMID 23649518 DOI: 10.2337/Db13-0305 |
0.762 |
|
| 2013 |
Song KH, Park J, Park JH, Natarajan R, Ha H. Fractalkine and its receptor mediate extracellular matrix accumulation in diabetic nephropathy in mice. Diabetologia. 56: 1661-9. PMID 23604552 DOI: 10.1007/S00125-013-2907-Z |
0.429 |
|
| 2013 |
Miao F, Chen Z, Zhang L, Wang J, Gao H, Wu X, Natarajan R. RNA-sequencing analysis of high glucose-treated monocytes reveals novel transcriptome signatures and associated epigenetic profiles. Physiological Genomics. 45: 287-99. PMID 23386205 DOI: 10.1152/Physiolgenomics.00001.2013 |
0.39 |
|
| 2013 |
Yuan H, Reddy MA, Sun G, Lanting L, Wang M, Kato M, Natarajan R. Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells. American Journal of Physiology. Renal Physiology. 304: F601-13. PMID 23235480 DOI: 10.1152/Ajprenal.00523.2012 |
0.409 |
|
| 2013 |
Reddy MA, Natarajan R. Role of epigenetic mechanisms in the vascular complications of diabetes. Sub-Cellular Biochemistry. 61: 435-54. PMID 23150262 DOI: 10.1007/978-94-007-4525-4_19 |
0.521 |
|
| 2012 |
Reddy MA, Park JT, Natarajan R. Epigenetic modifications and diabetic nephropathy. Kidney Research and Clinical Practice. 31: 139-50. PMID 26894019 DOI: 10.1016/J.Krcp.2012.07.004 |
0.52 |
|
| 2012 |
Leung A, Schones DE, Natarajan R. Using epigenetic mechanisms to understand the impact of common disease causing alleles. Current Opinion in Immunology. 24: 558-63. PMID 22857822 DOI: 10.1016/J.Coi.2012.07.004 |
0.309 |
|
| 2012 |
Kato M, Natarajan R. MicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy. Seminars in Nephrology. 32: 253-60. PMID 22835456 DOI: 10.1016/J.Semnephrol.2012.04.004 |
0.41 |
|
| 2012 |
Natarajan R, Putta S, Kato M. MicroRNAs and diabetic complications. Journal of Cardiovascular Translational Research. 5: 413-22. PMID 22552970 DOI: 10.1007/S12265-012-9368-5 |
0.717 |
|
| 2012 |
Jin W, Reddy MA, Chen Z, Putta S, Lanting L, Kato M, Park JT, Chandra M, Wang C, Tangirala RK, Natarajan R. Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells. The Journal of Biological Chemistry. 287: 15672-83. PMID 22431733 DOI: 10.1074/Jbc.M111.322669 |
0.657 |
|
| 2012 |
Miao F, Chen Z, Zhang L, Liu Z, Wu X, Yuan YC, Natarajan R. Profiles of epigenetic histone post-translational modifications at type 1 diabetes susceptible genes. The Journal of Biological Chemistry. 287: 16335-45. PMID 22431725 DOI: 10.1074/Jbc.M111.330373 |
0.448 |
|
| 2012 |
Kato M, Park JT, Natarajan R. MicroRNAs and the glomerulus. Experimental Cell Research. 318: 993-1000. PMID 22421514 DOI: 10.1016/J.Yexcr.2012.02.034 |
0.38 |
|
| 2012 |
Reddy MA, Jin W, Villeneuve L, Wang M, Lanting L, Todorov I, Kato M, Natarajan R. Pro-inflammatory role of microrna-200 in vascular smooth muscle cells from diabetic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 721-9. PMID 22247255 DOI: 10.1161/Atvbaha.111.241109 |
0.798 |
|
| 2012 |
Putta S, Lanting L, Sun G, Lawson G, Kato M, Natarajan R. Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 23: 458-69. PMID 22223877 DOI: 10.1681/Asn.2011050485 |
0.696 |
|
| 2011 |
Reddy MA, Natarajan R. Epigenetics in diabetic kidney disease. Journal of the American Society of Nephrology : Jasn. 22: 2182-5. PMID 22021712 DOI: 10.1681/Asn.2011060629 |
0.436 |
|
| 2011 |
Villeneuve LM, Natarajan R. Epigenetic mechanisms. Contributions to Nephrology. 170: 57-65. PMID 21659758 DOI: 10.1159/000324944 |
0.792 |
|
| 2011 |
Natarajan R. Drugs targeting epigenetic histone acetylation in vascular smooth muscle cells for restenosis and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 725-7. PMID 21411753 DOI: 10.1161/Atvbaha.111.222976 |
0.439 |
|
| 2011 |
Jin F, Li Y, Ren B, Natarajan R. PU.1 and C/EBP(alpha) synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers. Proceedings of the National Academy of Sciences of the United States of America. 108: 5290-5. PMID 21402921 DOI: 10.1073/Pnas.1017214108 |
0.321 |
|
| 2011 |
Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R. A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells. Kidney International. 80: 358-68. PMID 21389977 DOI: 10.1038/Ki.2011.43 |
0.663 |
|
| 2011 |
Patel-Chamberlin M, Wang Y, Satirapoj B, Phillips LM, Nast CC, Dai T, Watkins RA, Wu X, Natarajan R, Leng A, Ulanday K, Hirschberg RR, Lapage J, Nam EJ, Haq T, et al. Hematopoietic growth factor inducible neurokinin-1 (Gpnmb/Osteoactivin) is a biomarker of progressive renal injury across species. Kidney International. 79: 1138-48. PMID 21389974 DOI: 10.1038/Ki.2011.28 |
0.316 |
|
| 2011 |
Villeneuve LM, Reddy MA, Natarajan R. Epigenetics: deciphering its role in diabetes and its chronic complications. Clinical and Experimental Pharmacology & Physiology. 38: 451-9. PMID 21309809 DOI: 10.1111/J.1440-1681.2011.05497.X |
0.806 |
|
| 2011 |
Reddy MA, Natarajan R. Epigenetic mechanisms in diabetic vascular complications. Cardiovascular Research. 90: 421-9. PMID 21266525 DOI: 10.1093/Cvr/Cvr024 |
0.513 |
|
| 2010 |
Villeneuve LM, Natarajan R. Epigenetics of diabetic complications. Expert Review of Endocrinology & Metabolism. 5: 137-148. PMID 24077653 DOI: 10.1586/Eem.09.54 |
0.8 |
|
| 2010 |
Ma J, Phillips L, Wang Y, Dai T, LaPage J, Natarajan R, Adler SG. Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC. Bmc Complementary and Alternative Medicine. 10: 67. PMID 21073732 DOI: 10.1186/1472-6882-10-67 |
0.307 |
|
| 2010 |
Sun G, Reddy MA, Yuan H, Lanting L, Kato M, Natarajan R. Epigenetic histone methylation modulates fibrotic gene expression. Journal of the American Society of Nephrology : Jasn. 21: 2069-80. PMID 20930066 DOI: 10.1681/Asn.2010060633 |
0.418 |
|
| 2010 |
Kato M, Wang L, Putta S, Wang M, Yuan H, Sun G, Lanting L, Todorov I, Rossi JJ, Natarajan R. Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells. The Journal of Biological Chemistry. 285: 34004-15. PMID 20713358 DOI: 10.1074/Jbc.M110.165027 |
0.666 |
|
| 2010 |
Villeneuve LM, Kato M, Reddy MA, Wang M, Lanting L, Natarajan R. Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes. 59: 2904-15. PMID 20699419 DOI: 10.2337/Db10-0208 |
0.818 |
|
| 2010 |
Villeneuve LM, Natarajan R. The role of epigenetics in the pathology of diabetic complications. American Journal of Physiology. Renal Physiology. 299: F14-25. PMID 20462972 DOI: 10.1152/Ajprenal.00200.2010 |
0.798 |
|
| 2010 |
Meng L, Park J, Cai Q, Lanting L, Reddy MA, Natarajan R. Diabetic conditions promote binding of monocytes to vascular smooth muscle cells and their subsequent differentiation. American Journal of Physiology. Heart and Circulatory Physiology. 298: H736-45. PMID 20008269 DOI: 10.1152/Ajpheart.00935.2009 |
0.476 |
|
| 2009 |
Kato M, Natarajan R. microRNA cascade in diabetic kidney disease: Big impact initiated by a small RNA. Cell Cycle (Georgetown, Tex.). 8: 3613-4. PMID 19884793 DOI: 10.4161/Cc.8.22.9816 |
0.349 |
|
| 2009 |
Kato M, Arce L, Natarajan R. MicroRNAs and their role in progressive kidney diseases. Clinical Journal of the American Society of Nephrology : Cjasn. 4: 1255-66. PMID 19581401 DOI: 10.2215/Cjn.00520109 |
0.395 |
|
| 2009 |
Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I, Gunn A, Nakagawa Y, Shimano H, Todorov I, Rossi JJ, Natarajan R. TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nature Cell Biology. 11: 881-9. PMID 19543271 DOI: 10.1038/Ncb1897 |
0.645 |
|
| 2009 |
Dai T, Patel-Chamberlin M, Natarajan R, Todorov I, Ma J, LaPage J, Phillips L, Nast CC, Becerra D, Chuang P, Tong L, de Belleroche J, Wells DJ, Wang Y, Adler SG. Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology. 150: 3031-9. PMID 19325007 DOI: 10.1210/En.2008-0732 |
0.34 |
|
| 2009 |
Reddy MA, Sahar S, Villeneuve LM, Lanting L, Natarajan R. Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 387-93. PMID 19095999 DOI: 10.1161/Atvbaha.108.179150 |
0.746 |
|
| 2008 |
Shanmugam N, Reddy MA, Natarajan R. Distinct roles of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100b, a ligand of the receptor for advanced glycation end products. The Journal of Biological Chemistry. 283: 36221-33. PMID 18854308 DOI: 10.1074/Jbc.M806322200 |
0.398 |
|
| 2008 |
Miao F, Smith DD, Zhang L, Min A, Feng W, Natarajan R. Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes. Diabetes. 57: 3189-98. PMID 18776137 DOI: 10.2337/Db08-0645 |
0.484 |
|
| 2008 |
Reddy MA, Villeneuve LM, Wang M, Lanting L, Natarajan R. Role of the lysine-specific demethylase 1 in the proinflammatory phenotype of vascular smooth muscle cells of diabetic mice. Circulation Research. 103: 615-23. PMID 18688044 DOI: 10.1161/Circresaha.108.175190 |
0.818 |
|
| 2008 |
Li Y, Reddy MA, Miao F, Shanmugam N, Yee JK, Hawkins D, Ren B, Natarajan R. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation. The Journal of Biological Chemistry. 283: 26771-81. PMID 18650421 DOI: 10.1074/Jbc.M802800200 |
0.439 |
|
| 2008 |
Villeneuve LM, Reddy MA, Lanting LL, Wang M, Meng L, Natarajan R. Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proceedings of the National Academy of Sciences of the United States of America. 105: 9047-52. PMID 18579779 DOI: 10.1073/Pnas.0803623105 |
0.808 |
|
| 2008 |
Yuan H, Lanting L, Xu ZG, Li SL, Swiderski P, Putta S, Jonnalagadda M, Kato M, Natarajan R. Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes. American Journal of Physiology. Renal Physiology. 295: F605-17. PMID 18562637 DOI: 10.1152/Ajprenal.90268.2008 |
0.697 |
|
| 2008 |
Figarola JL, Loera S, Weng Y, Shanmugam N, Natarajan R, Rahbar S. LR-90 prevents dyslipidaemia and diabetic nephropathy in the Zucker diabetic fatty rat. Diabetologia. 51: 882-91. PMID 18317729 DOI: 10.1007/S00125-008-0935-X |
0.442 |
|
| 2008 |
Miao F, Wu X, Zhang L, Riggs AD, Natarajan R. Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes. Journal of Immunology (Baltimore, Md. : 1950). 180: 2264-9. PMID 18250434 DOI: 10.4049/Jimmunol.180.4.2264 |
0.347 |
|
| 2008 |
Xu ZG, Yuan H, Lanting L, Li SL, Wang M, Shanmugam N, Kato M, Adler SG, Reddy MA, Natarajan R. Products of 12/15-lipoxygenase upregulate the angiotensin II receptor. Journal of the American Society of Nephrology : Jasn. 19: 559-69. PMID 18235084 DOI: 10.1681/Asn.2007080939 |
0.44 |
|
| 2008 |
Dwarakanath RS, Sahar S, Lanting L, Wang N, Stemerman MB, Natarajan R, Reddy MA. Viral vector-mediated 12/15-lipoxygenase overexpression in vascular smooth muscle cells enhances inflammatory gene expression and migration. Journal of Vascular Research. 45: 132-42. PMID 17943024 DOI: 10.1159/000109966 |
0.413 |
|
| 2007 |
Guha M, Xu ZG, Tung D, Lanting L, Natarajan R. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3355-68. PMID 17554073 DOI: 10.1096/Fj.06-6713Com |
0.461 |
|
| 2007 |
Sahar S, Reddy MA, Wong C, Meng L, Wang M, Natarajan R. Cooperation of SRC-1 and p300 with NF-kappaB and CREB in angiotensin II-induced IL-6 expression in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1528-34. PMID 17495236 DOI: 10.1161/Atvbaha.107.145862 |
0.336 |
|
| 2007 |
Kato M, Zhang J, Wang M, Lanting L, Yuan H, Rossi JJ, Natarajan R. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proceedings of the National Academy of Sciences of the United States of America. 104: 3432-7. PMID 17360662 DOI: 10.1073/Pnas.0611192104 |
0.394 |
|
| 2007 |
Miao F, Wu X, Zhang L, Yuan YC, Riggs AD, Natarajan R. Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. The Journal of Biological Chemistry. 282: 13854-63. PMID 17339327 DOI: 10.1074/Jbc.M609446200 |
0.445 |
|
| 2007 |
Figarola JL, Shanmugam N, Natarajan R, Rahbar S. Anti-inflammatory effects of the advanced glycation end product inhibitor LR-90 in human monocytes. Diabetes. 56: 647-55. PMID 17327432 DOI: 10.2337/Db06-0936 |
0.41 |
|
| 2006 |
Kato M, Yuan H, Xu ZG, Lanting L, Li SL, Wang M, Hu MC, Reddy MA, Natarajan R. Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease. Journal of the American Society of Nephrology : Jasn. 17: 3325-35. PMID 17082237 DOI: 10.1681/Asn.2006070754 |
0.413 |
|
| 2006 |
Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L, Natarajan R. Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes. 55: 2611-9. PMID 16936211 DOI: 10.2337/Db06-0164 |
0.473 |
|
| 2006 |
Shanmugam N, Ransohoff RM, Natarajan R. Interferon-gamma-inducible protein (IP)-10 mRNA stabilized by RNA-binding proteins in monocytes treated with S100b. The Journal of Biological Chemistry. 281: 31212-21. PMID 16931519 DOI: 10.1074/Jbc.M602445200 |
0.441 |
|
| 2006 |
Reddy MA, Li SL, Sahar S, Kim YS, Xu ZG, Lanting L, Natarajan R. Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation end products in vascular smooth muscle cells. The Journal of Biological Chemistry. 281: 13685-93. PMID 16551628 DOI: 10.1074/Jbc.M511425200 |
0.421 |
|
| 2006 |
Xu ZG, Li SL, Lanting L, Kim YS, Shanmugam N, Reddy MA, Natarajan R. Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: potential role in diabetic nephropathy. Kidney International. 69: 512-9. PMID 16514433 DOI: 10.1038/Sj.Ki.5000137 |
0.432 |
|
| 2006 |
Miao F, Li S, Chavez V, Lanting L, Natarajan R. Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. Molecular Endocrinology (Baltimore, Md.). 20: 1562-73. PMID 16497732 DOI: 10.1210/Me.2005-0365 |
0.369 |
|
| 2006 |
Wen Y, Gu J, Li SL, Reddy MA, Natarajan R, Nadler JL. Elevated glucose and diabetes promote interleukin-12 cytokine gene expression in mouse macrophages. Endocrinology. 147: 2518-25. PMID 16455783 DOI: 10.1210/En.2005-0519 |
0.414 |
|
| 2006 |
Dai T, Natarajan R, Nast CC, LaPage J, Chuang P, Sim J, Tong L, Chamberlin M, Wang S, Adler SG. Glucose and diabetes: effects on podocyte and glomerular p38MAPK, heat shock protein 25, and actin cytoskeleton. Kidney International. 69: 806-14. PMID 16421517 DOI: 10.1038/Sj.Ki.5000033 |
0.327 |
|
| 2005 |
Natarajan R, Cai Q. Monocyte retention in the pathology of atherosclerosis. Future Cardiology. 1: 331-40. PMID 19804116 DOI: 10.1517/14796678.1.3.331 |
0.372 |
|
| 2005 |
Shanmugam N, Todorov IT, Nair I, Omori K, Reddy MA, Natarajan R. Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice. Diabetologia. 49: 100-7. PMID 16341840 DOI: 10.1007/S00125-005-0065-7 |
0.454 |
|
| 2005 |
Taylor AM, Hanchett R, Natarajan R, Hedrick CC, Forrest S, Nadler JL, McNamara CA. The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growth. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2069-74. PMID 16037566 DOI: 10.1161/01.Atv.0000178992.40088.F2 |
0.372 |
|
| 2005 |
Sahar S, Dwarakanath RS, Reddy MA, Lanting L, Todorov I, Natarajan R. Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in vascular smooth muscle cells: a novel cross-talk in the pathogenesis of atherosclerosis. Circulation Research. 96: 1064-71. PMID 15860756 DOI: 10.1161/01.Res.0000168210.10358.F4 |
0.307 |
|
| 2005 |
Xu ZG, Lanting L, Vaziri ND, Li Z, Sepassi L, Rodriguez-Iturbe B, Natarajan R. Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade. Circulation. 111: 1962-9. PMID 15837950 DOI: 10.1161/01.Cir.0000161831.07637.63 |
0.304 |
|
| 2005 |
Xu ZG, Yoo TH, Ryu DR, Cheon Park H, Ha SK, Han DS, Adler SG, Natarajan R, Kang SW. Angiotensin II receptor blocker inhibits p27Kip1 expression in glucose-stimulated podocytes and in diabetic glomeruli. Kidney International. 67: 944-52. PMID 15698433 DOI: 10.1111/j.1523-1755.2005.00158.x |
0.322 |
|
| 2005 |
Xu ZG, Ryu DR, Yoo TH, Jung DS, Kim JJ, Kim HJ, Choi HY, Kim JS, Adler SG, Natarajan R, Han DS, Kang SW. P-Cadherin is decreased in diabetic glomeruli and in glucose-stimulated podocytes in vivo and in vitro studies. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 20: 524-31. PMID 15647309 DOI: 10.1093/Ndt/Gfh642 |
0.433 |
|
| 2005 |
Kim YS, Xu ZG, Reddy MA, Li SL, Lanting L, Sharma K, Adler SG, Natarajan R. Novel interactions between TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial cells. Journal of the American Society of Nephrology : Jasn. 16: 352-62. PMID 15615821 DOI: 10.1681/Asn.2004070568 |
0.313 |
|
| 2005 |
González-Núñez D, Solé M, Natarajan R, Poch E. 12-Lipoxygenase metabolism in mouse distal convoluted tubule cells. Kidney International. 67: 178-86. PMID 15610241 DOI: 10.1111/J.1523-1755.2005.00068.X |
0.402 |
|
| 2005 |
Li SL, Dwarakanath RS, Cai Q, Lanting L, Natarajan R. Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs. Journal of Lipid Research. 46: 220-9. PMID 15576842 DOI: 10.1194/Jlr.M400328-Jlr200 |
0.427 |
|
| 2004 |
Cai Q, Lanting L, Natarajan R. Interaction of monocytes with vascular smooth muscle cells regulates monocyte survival and differentiation through distinct pathways. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2263-70. PMID 15458980 DOI: 10.1161/01.Atv.0000146552.16943.5E |
0.339 |
|
| 2004 |
Natarajan R, Nadler JL. Lipid inflammatory mediators in diabetic vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1542-8. PMID 15166011 DOI: 10.1161/01.Atv.0000133606.69732.4C |
0.473 |
|
| 2004 |
Srinivasan S, Bolick DT, Hatley ME, Natarajan R, Reilly KB, Yeh M, Chrestensen C, Sturgill TW, Hedrick CC. Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes. The Journal of Biological Chemistry. 279: 31930-6. PMID 15145956 DOI: 10.1074/Jbc.M400753200 |
0.395 |
|
| 2004 |
Cai Q, Lanting L, Natarajan R. Growth factors induce monocyte binding to vascular smooth muscle cells: implications for monocyte retention in atherosclerosis. American Journal of Physiology. Cell Physiology. 287: C707-14. PMID 15140748 DOI: 10.1152/Ajpcell.00170.2004 |
0.364 |
|
| 2004 |
Dwarakanath RS, Sahar S, Reddy MA, Castanotto D, Rossi JJ, Natarajan R. Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B). Journal of Molecular and Cellular Cardiology. 36: 585-95. PMID 15081318 DOI: 10.1016/J.Yjmcc.2004.02.007 |
0.368 |
|
| 2004 |
Shanmugam N, Gaw Gonzalo IT, Natarajan R. Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes. Diabetes. 53: 795-802. PMID 14988266 DOI: 10.2337/Diabetes.53.3.795 |
0.433 |
|
| 2004 |
Miao F, Gonzalo IG, Lanting L, Natarajan R. In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. The Journal of Biological Chemistry. 279: 18091-7. PMID 14976218 DOI: 10.1074/Jbc.M311786200 |
0.419 |
|
| 2004 |
Reilly KB, Srinivasan S, Hatley ME, Patricia MK, Lannigan J, Bolick DT, Vandenhoff G, Pei H, Natarajan R, Nadler JL, Hedrick CC. 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo. The Journal of Biological Chemistry. 279: 9440-50. PMID 14676201 DOI: 10.1074/Jbc.M303857200 |
0.34 |
|
| 2003 |
Kang SW, Natarajan R, Shahed A, Nast CC, LaPage J, Mundel P, Kashtan C, Adler SG. Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes. Journal of the American Society of Nephrology : Jasn. 14: 3178-87. PMID 14638916 DOI: 10.1097/01.Asn.0000099702.16315.De |
0.332 |
|
| 2003 |
Natarajan R, Nadler JL. Lipoxygenases and lipid signaling in vascular cells in diabetes. Frontiers in Bioscience : a Journal and Virtual Library. 8: s783-95. PMID 12957878 DOI: 10.2741/1144 |
0.45 |
|
| 2003 |
Shanmugam N, Kim YS, Lanting L, Natarajan R. Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. The Journal of Biological Chemistry. 278: 34834-44. PMID 12837757 DOI: 10.1074/Jbc.M302828200 |
0.432 |
|
| 2003 |
Shanmugam N, Reddy MA, Guha M, Natarajan R. High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes. 52: 1256-64. PMID 12716761 DOI: 10.2337/Diabetes.52.5.1256 |
0.425 |
|
| 2003 |
Reddy MA, Kim YS, Lanting L, Natarajan R. Reduced growth factor responses in vascular smooth muscle cells derived from 12/15-lipoxygenase-deficient mice. Hypertension. 41: 1294-300. PMID 12707289 DOI: 10.1161/01.Hyp.0000069011.18333.08 |
0.388 |
|
| 2003 |
Natarajan R, Reddy MA. HETEs/EETs in renal glomerular and epithelial cell functions. Current Opinion in Pharmacology. 3: 198-203. PMID 12681244 DOI: 10.1016/S1471-4892(03)00015-8 |
0.399 |
|
| 2002 |
Reddy MA, Adler SG, Kim YS, Lanting L, Rossi J, Kang SW, Nadler JL, Shahed A, Natarajan R. Interaction of MAPK and 12-lipoxygenase pathways in growth and matrix protein expression in mesangial cells. American Journal of Physiology. Renal Physiology. 283: F985-94. PMID 12372774 DOI: 10.1152/Ajprenal.00181.2002 |
0.334 |
|
| 2002 |
Natarajan R, Gerrity RG, Gu JL, Lanting L, Thomas L, Nadler JL. Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model. Diabetologia. 45: 125-33. PMID 11845232 DOI: 10.1007/S125-002-8253-X |
0.429 |
|
| 2001 |
Natarajan R, Reddy MA, Malik KU, Fatima S, Khan BV. Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1408-13. PMID 11557664 DOI: 10.1161/Hq0901.095278 |
0.352 |
|
| 2001 |
Coffey MJ, Natarajan R, Chumley PH, Coles B, Thimmalapura PR, Nowell M, Kühn H, Lewis MJ, Freeman BA, O'Donnell VB. Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation. Proceedings of the National Academy of Sciences of the United States of America. 98: 8006-11. PMID 11427723 DOI: 10.1073/Pnas.141136098 |
0.322 |
|
| 2001 |
Gerrity RG, Natarajan R, Nadler JL, Kimsey T. Diabetes-induced accelerated atherosclerosis in swine. Diabetes. 50: 1654-65. PMID 11423488 DOI: 10.2337/Diabetes.50.7.1654 |
0.428 |
|
| 2001 |
Patricia MK, Natarajan R, Dooley AN, Hernandez F, Gu JL, Berliner JA, Rossi JJ, Nadler JL, Meidell RS, Hedrick CC. Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells. Circulation Research. 88: 659-65. PMID 11304487 DOI: 10.1161/Hh0701.088838 |
0.36 |
|
| 2001 |
Kang SW, Adler SG, Nast CC, LaPage J, Gu JL, Nadler JL, Natarajan R. 12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy. Kidney International. 59: 1354-62. PMID 11260396 DOI: 10.1046/J.1523-1755.2001.0590041354.X |
0.428 |
|
| 2001 |
Gu J, Liu Y, Wen Y, Natarajan R, Lanting L, Nadler JL. Evidence that increased 12-lipoxygenase activity induces apoptosis in fibroblasts. Journal of Cellular Physiology. 186: 357-365. PMID 11169974 DOI: 10.1002/1097-4652(200103)186:3<357::Aid-Jcp1034>3.0.Co;2-E |
0.324 |
|
| 2000 |
Rahbar S, Natarajan R, Yerneni K, Scott S, Gonzales N, Nadler JL. Evidence that pioglitazone, metformin and pentoxifylline are inhibitors of glycation. Clinica Chimica Acta; International Journal of Clinical Chemistry. 301: 65-77. PMID 11020463 DOI: 10.1016/S0009-8981(00)00327-2 |
0.39 |
|
| 2000 |
Guha M, Bai W, Nadler JL, Natarajan R. Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways. The Journal of Biological Chemistry. 275: 17728-39. PMID 10837498 DOI: 10.1074/Jbc.275.23.17728 |
0.36 |
|
| 1999 |
Natarajan R, Pei H, Gu JL, Sarma JM, Nadler J. Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury. Cardiovascular Research. 41: 489-99. PMID 10341849 DOI: 10.1016/S0008-6363(98)00312-5 |
0.334 |
|
| 1999 |
Yerneni KK, Bai W, Khan BV, Medford RM, Natarajan R. Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells. Diabetes. 48: 855-64. PMID 10102704 DOI: 10.2337/Diabetes.48.4.855 |
0.385 |
|
| 1999 |
Natarajan R, Scott S, Bai W, Yerneni KK, Nadler J. Angiotensin II signaling in vascular smooth muscle cells under high glucose conditions. Hypertension (Dallas, Tex. : 1979). 33: 378-84. PMID 9931133 DOI: 10.1161/01.Hyp.33.1.378 |
0.356 |
|
| 1998 |
Goalstone ML, Natarajan R, Standley PR, Walsh MF, Leitner JW, Carel K, Scott S, Nadler J, Sowers JR, Draznin B. Insulin Potentiates Platelet-Derived Growth Factor Action in Vascular Smooth Muscle Cells* * This work was supported by grants from the VA Research Service, the NIH (HL-48920 to R.N., HD-24497-06 to J.S.), PO-1-HL-55798 (to J.N. and R.N.), jointly funded by the NIH and the Juvenile Diabetes Foundation, the American Heart Association, a fellowship support from the American Heart Association (to M.G.), HealthONE Foundation: Diabetes and Endocrine Research and Education Fund, and Foundation for Biomedical Education and Research. Endocrinology. 139: 4067-4072. PMID 28200187 DOI: 10.1210/Endo.139.10.6270 |
0.347 |
|
| 1997 |
Natarajan R, Bai W, Lanting L, Gonzales N, Nadler J. Effects of high glucose on vascular endothelial growth factor expression in vascular smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 273: H2224-H2231. PMID 29586462 DOI: 10.1152/Ajpheart.1997.273.5.H2224 |
0.377 |
|
| 1997 |
Natarajan R, Rosdahl J, Gonzales N, Bai W. Regulation of 12-lipoxygenase by cytokines in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 30: 873-9. PMID 9336387 DOI: 10.1161/01.Hyp.30.4.873 |
0.353 |
|
| 1997 |
Natarajan R, Lanting L, Bai W, Bravo EL, Nadler J. The role of nitric oxide in the regulation of aldosterone synthesis by adrenal glomerulosa cells The Journal of Steroid Biochemistry and Molecular Biology. 61: 47-53. PMID 9328209 DOI: 10.1016/S0960-0760(97)00004-6 |
0.307 |
|
| 1996 |
Natarajan R, Bai W, Rangarajan V, Gonzales N, Gu JL, Lanting L, Nadler JL. Platelet-derived growth factor BB mediated regulation of 12-lipoxygenase in porcine aortic smooth muscle cells. Journal of Cellular Physiology. 169: 391-400. PMID 8908207 DOI: 10.1002/(Sici)1097-4652(199611)169:2<391::Aid-Jcp19>3.0.Co;2-C |
0.415 |
|
| 1996 |
Natarajan R, Lanting L, Gonzales N, Nadler J. Formation of an F2-isoprostane in vascular smooth muscle cells by elevated glucose and growth factors. The American Journal of Physiology. 271: H159-65. PMID 8760171 DOI: 10.1152/Ajpheart.1996.271.1.H159 |
0.337 |
|
| 1996 |
Antonipillai I, Nadler J, Vu EJ, Bughi S, Natarajan R, Horton R. A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease. The Journal of Clinical Endocrinology and Metabolism. 81: 1940-5. PMID 8626861 DOI: 10.1210/jcem.81.5.8626861 |
0.308 |
|
| 1995 |
Kim JA, Gu JL, Natarajan R, Berliner JA, Nadler JL. A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells: Evidence for upregulation by angiotensin II Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 942-948. PMID 7600127 DOI: 10.1161/01.Atv.15.7.942 |
0.344 |
|
| 1995 |
Bleich D, Chen S, Gu JL, Thomas L, Scott S, Gonzales N, Natarajan R, Nadler JL. Interleukin-1β Regulates the Expression of a Leukocyte Type of 12-Lipoxygenase in Rat Islets and RIN m5F Cells Endocrinology. 136: 5736-5744. PMID 7588331 DOI: 10.1210/Endo.136.12.7588331 |
0.319 |
|
| 1995 |
Gu JL, Veerapanane D, Rossi J, Natarajan R, Thomas L, Nadler J. Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells. Circulation Research. 77: 14-20. PMID 7540514 DOI: 10.1161/01.Res.77.1.14 |
0.374 |
|
| 1995 |
Antonipillai I, Jost-Vu E, Natarajan R, Nadler J, Horton R. Renin response to 12-hydroxyeicosatetraenoic acid is increased in diabetic rats. Diabetes. 44: 321-5. PMID 7533733 DOI: 10.2337/Diab.44.3.321 |
0.422 |
|
| 1994 |
Natarajan R, Lanting L, Xu L, Nadler J. Role of specific isoforms of protein kinase C in angiotensin II and lipoxygenase action in rat adrenal glomerulosa cells Molecular and Cellular Endocrinology. 101: 59-66. PMID 9397937 DOI: 10.1016/0303-7207(94)90219-4 |
0.306 |
|
| 1994 |
Natarajan R, Gonzales N, Lanting L, Nadler J. Role of the lipoxygenase pathway in angiotensin II-induced vascular smooth muscle cell hypertrophy. Hypertension (Dallas, Tex. : 1979). 23: I142-7. PMID 8282345 DOI: 10.1161/01.Hyp.23.1_Suppl.I142 |
0.338 |
|
| 1994 |
Gu JL, Natarajan R, Ben-Ezra J, Valente G, Scott S, Yoshimoto T, Yamamoto S, Rossi JJ, Nadler JL. Evidence that a leukocyte type of 12-lipoxygenase is expressed and regulated by angiotensin II in human adrenal glomerulosa cells. Endocrinology. 134: 70-7. PMID 8275971 DOI: 10.1210/Endo.134.1.8275971 |
0.303 |
|
| 1993 |
Natarajan R, Gu JL, Rossi J, Gonzales N, Lanting L, Xu L, Nadler J. Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 4947-51. PMID 8506339 DOI: 10.1073/Pnas.90.11.4947 |
0.45 |
|
| 1992 |
Natarajan R, Gonzales N, Xu L, Nadler JL. Vascular smooth muscle cells exhibit increased growth in response to elevated glucose. Biochemical and Biophysical Research Communications. 187: 552-60. PMID 1520346 DOI: 10.1016/S0006-291X(05)81529-3 |
0.354 |
|
| 1992 |
Natarajan R, Gonzales N, Hornsby PJ, Nadler J. Mechanism of angiotensin II-induced proliferation in bovine adrenocortical cells. Endocrinology. 131: 1174-80. PMID 1505459 DOI: 10.1210/Endo.131.3.1505459 |
0.354 |
|
| 1992 |
Natarajan R, Nadler J. Platelet-derived growth factor is a potent inhibitor of angiotensin II-induced aldosterone synthesis Molecular and Cellular Endocrinology. 83: 57-63. PMID 1312960 DOI: 10.1016/0303-7207(92)90195-C |
0.335 |
|
| 1991 |
Natarajan R, Nadler J. Angiotensin II-induced aldosterone synthesis is potentiated by epidermal growth factor Endocrinology. 128: 2285-2290. PMID 1850348 DOI: 10.1210/Endo-128-5-2285 |
0.322 |
|
| 1988 |
Nadler JL, Natarajan R, Stern N. Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells. The Journal of Clinical Investigation. 80: 1763-9. PMID 2824567 DOI: 10.1172/Jci113269 |
0.335 |
|
| 1958 |
DESHPANDE SM, NATARAJAN R. Potentiometric and amperometric titrations of ascorbic acid. Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 47: 633-5. PMID 13575226 |
0.448 |
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