Year |
Citation |
Score |
2024 |
Taylor MK, Burns JM, Choi IY, Herda TJ, Lee P, Smith AN, Sullivan DK, Swerdlow RH, Wilkins HM. Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease. Pilot and Feasibility Studies. 10: 42. PMID 38414003 DOI: 10.1186/s40814-024-01469-5 |
0.332 |
|
2023 |
Alghusen IM, Carman MS, Wilkins H, Ephrame SJ, Qiang A, Dias WB, Fedosyuk H, Denson AR, Swerdlow RH, Slawson C. O-GlcNAc regulates the mitochondrial integrated stress response by regulating ATF4. Frontiers in Aging Neuroscience. 15: 1326127. PMID 38192280 DOI: 10.3389/fnagi.2023.1326127 |
0.335 |
|
2023 |
Pal R, Hui D, Menchen H, Zhao H, Mozziconacci O, Wilkins H, Blagg BSJ, Schöneich C, Swerdlow RH, Michaelis ML, Michaelis EK. Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target. Frontiers in Aging Neuroscience. 15: 1282855. PMID 38035268 DOI: 10.3389/fnagi.2023.1282855 |
0.567 |
|
2023 |
Shvetcov A, Thomson S, Spathos J, Cho AN, Wilkins HM, Andrews SJ, Delerue F, Couttas TA, Issar JK, Isik F, Kaur S, Drummond E, Dobson-Stone C, Duffy SL, Rogers NM, et al. Blood-Based Transcriptomic Biomarkers Are Predictive of Neurodegeneration Rather Than Alzheimer's Disease. International Journal of Molecular Sciences. 24. PMID 37834458 DOI: 10.3390/ijms241915011 |
0.509 |
|
2023 |
Flannagan K, Stopperan JA, Hauger BM, Troutwine BR, Lysaker CR, Strope TA, Csikos Drummond V, Gilmore CA, Swerdlow NA, Draper JM, Gouvion CM, Vivian JL, Haeri M, Swerdlow RH, Wilkins HM. Cell type and sex specific mitochondrial phenotypes in iPSC derived models of Alzheimer's disease. Frontiers in Molecular Neuroscience. 16: 1201015. PMID 37614699 DOI: 10.3389/fnmol.2023.1201015 |
0.6 |
|
2023 |
Finney CA, Wilkins HM, Swerdlow RH, Brown DA. Activators of neurotoxic microglia in neurodegeneration: is the answer in blood? Immunology and Cell Biology. PMID 37524376 DOI: 10.1111/imcb.12674 |
0.431 |
|
2023 |
Gabrielli AP, Weidling I, Ranjan A, Wang X, Novikova L, Chowdhury SR, Menta B, Berkowicz A, Wilkins HM, Peterson KR, Swerdlow RH. Mitochondria Profoundly Influence Apolipoprotein E Biology. Journal of Alzheimer's Disease : Jad. PMID 36776072 DOI: 10.3233/JAD-221177 |
0.807 |
|
2023 |
Wilkins HM. Interactions between amyloid, amyloid precursor protein, and mitochondria. Biochemical Society Transactions. 51: 173-182. PMID 36688439 DOI: 10.1042/BST20220518 |
0.395 |
|
2022 |
Linseman DA, Winter AN, Wilkins HM. The 2-Oxoglutarate Carrier Is S-Nitrosylated in the Spinal Cord of G93A Mutant hSOD1 Mice Resulting in Disruption of Mitochondrial Glutathione Transport. Biomedicines. 11. PMID 36672568 DOI: 10.3390/biomedicines11010061 |
0.627 |
|
2022 |
Koppel SJ, Wilkins HM, Weidling IW, Wang X, Menta BW, Swerdlow RH. β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence. Mitochondrion. 68: 125-137. PMID 36516926 DOI: 10.1016/j.mito.2022.12.004 |
0.782 |
|
2022 |
Strope TA, Wilkins HM. Amyloid precursor protein and mitochondria. Current Opinion in Neurobiology. 78: 102651. PMID 36462447 DOI: 10.1016/j.conb.2022.102651 |
0.391 |
|
2022 |
Strope TA, Birky CJ, Wilkins HM. The Role of Bioenergetics in Neurodegeneration. International Journal of Molecular Sciences. 23. PMID 36012480 DOI: 10.3390/ijms23169212 |
0.342 |
|
2022 |
Troutwine BR, Strope TA, Franczak E, Lysaker CR, Hamid L, Mansel C, Stopperan JA, Gouvion CM, Haeri M, Swerdlow RH, Wilkins HM. Mitochondrial function and Aβ in Alzheimer's disease postmortem brain. Neurobiology of Disease. 105781. PMID 35667615 DOI: 10.1016/j.nbd.2022.105781 |
0.626 |
|
2022 |
Wang X, Berkowicz A, King K, Menta B, Gabrielli AP, Novikova L, Troutwine B, Pleen J, Wilkins HM, Swerdlow RH. Pharmacologic enrichment of exosome yields and mitochondrial cargo. Mitochondrion. 64: 136-144. PMID 35398304 DOI: 10.1016/j.mito.2022.04.001 |
0.814 |
|
2022 |
Sandberg AA, Manning E, Wilkins HM, Mazzarino R, Minckley T, Swerdlow RH, Patterson D, Qin Y, Linseman DA. Mitochondrial Targeting of Amyloid-β Protein Precursor Intracellular Domain Induces Hippocampal Cell Death via a Mechanism Distinct from Amyloid-β. Journal of Alzheimer's Disease : Jad. PMID 35253745 DOI: 10.3233/JAD-215108 |
0.719 |
|
2021 |
Wilkins HM, Troutwine BR, Menta BW, Manley SJ, Strope TA, Lysaker CR, Swerdlow RH. Mitochondrial Membrane Potential Influences Amyloid-β Protein Precursor Localization and Amyloid-β Secretion. Journal of Alzheimer's Disease : Jad. PMID 34806611 DOI: 10.3233/JAD-215280 |
0.81 |
|
2021 |
Morris JK, McCoin CS, Fuller KN, John CS, Wilkins HM, Green ZD, Wang X, Sharma P, Burns JM, Vidoni ED, Mahnken JD, Shankar K, Swerdlow RH, Thyfault JP. Mild Cognitive Impairment and Donepezil Impact Mitochondrial Respiratory Capacity in Skeletal Muscle. Function (Oxford, England). 2: zqab045. PMID 34661111 DOI: 10.1093/function/zqab045 |
0.724 |
|
2021 |
Wilkins HM, Swerdlow RH. Mitochondrial links between brain aging and Alzheimer's disease. Translational Neurodegeneration. 10: 33. PMID 34465385 DOI: 10.1186/s40035-021-00261-2 |
0.55 |
|
2021 |
Pope CA, Wilkins HM, Swerdlow RH, Wolfe MS. Mutations in the Amyloid-β Protein Precursor Reduce Mitochondrial Function and Alter Gene Expression Independent of 42-Residue Amyloid-β Peptide. Journal of Alzheimer's Disease : Jad. PMID 34366346 DOI: 10.3233/JAD-210366 |
0.536 |
|
2021 |
Tungtur SK, Wilkins HM, Rogers RS, Badawi Y, Sage JM, Agbas A, Jawdat O, Barohn RJ, Swerdlow RH, Nishimune H. Oxaloacetate treatment preserves motor function in SOD1 mice and normalizes select neuroinflammation-related parameters in the spinal cord. Scientific Reports. 11: 11051. PMID 34040085 DOI: 10.1038/s41598-021-90438-6 |
0.45 |
|
2021 |
Wilkins HM, Wang X, Menta BW, Koppel SJ, Bothwell R, Becker AM, Anderson H, Schwartz E, Pei D, Yellapu NK, Chalise P, Gouvion CM, Haeri M, Burns JM, Swerdlow RH. Bioenergetic and inflammatory systemic phenotypes in Alzheimer's disease APOE ε4-carriers. Aging Cell. e13356. PMID 33939248 DOI: 10.1111/acel.13356 |
0.814 |
|
2021 |
Koppel SJ, Pei D, Wilkins HM, Weidling IW, Wang X, Menta BW, Perez-Ortiz J, Kalani A, Manley S, Novikova L, Koestler DC, Swerdlow RH. A Ketogenic Diet Differentially Affects Neuron And Astrocyte Transcription. Journal of Neurochemistry. PMID 33539571 DOI: 10.1111/jnc.15313 |
0.77 |
|
2020 |
Morris JK, John CS, Green ZD, Wilkins HM, Wang X, Kamat A, Swerdlow RS, Vidoni ED, Petersen ME, O'Bryant SE, Honea RA, Burns JM. Characterization of the Meal-Stimulated Incretin Response and Relationship With Structural Brain Outcomes in Aging and Alzheimer's Disease. Frontiers in Neuroscience. 14: 608862. PMID 33328877 DOI: 10.3389/fnins.2020.608862 |
0.634 |
|
2020 |
Flax J, Wilkins HM, Miller R, Griffith S, Cork GK, Qiang A, Thompson J, Swerdlow RH, Slawson C. OGA Inhibition Alters Energetics and Nutrient Sensing in Alzheimer's Disease Cytoplasmic Hybrids. Journal of Alzheimer's Disease : Jad. PMID 33285636 DOI: 10.3233/JAD-200996 |
0.598 |
|
2020 |
Wang X, Weidling I, Koppel S, Menta B, Perez Ortiz J, Kalani A, Wilkins HM, Swerdlow RH. Detection of Mitochondria-Pertinent Components in Exosomes. Mitochondrion. PMID 32980480 DOI: 10.1016/j.mito.2020.09.006 |
0.785 |
|
2020 |
Weidling IW, Wilkins HM, Koppel SJ, Hutfles L, Wang X, Kalani A, Menta BW, Ryan B, Perez-Ortiz J, Gamblin TC, Swerdlow RH. Mitochondrial DNA Manipulations Affect Tau Oligomerization. Journal of Alzheimer's Disease : Jad. PMID 32804126 DOI: 10.3233/Jad-200286 |
0.784 |
|
2020 |
Vidoni ED, Choi IY, Lee P, Reed G, Zhang N, Pleen J, Mahnken JD, Clutton J, Becker A, Sherry E, Bothwell R, Anderson H, Harris RA, Brooks W, Wilkins HM, et al. Safety and target engagement profile of two oxaloacetate doses in Alzheimer's patients. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32715609 DOI: 10.1002/Alz.12156 |
0.566 |
|
2020 |
Swerdlow RH, Hui D, Chalise P, Sharma P, Wang X, Andrews SJ, Pa J, Mahnken JD, Morris J, Wilkins HM, Burns JM, Michaelis ML, Michaelis EK. Exploratory analysis of mtDNA haplogroups in two Alzheimer's longitudinal cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32543785 DOI: 10.1002/Alz.12119 |
0.635 |
|
2019 |
Watts A, Wilkins HM, Michaelis E, Swerdlow RH. TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE ɛ3 Homozygotes. Journal of Alzheimer's Disease : Jad. PMID 31322569 DOI: 10.3233/Jad-190293 |
0.505 |
|
2019 |
Ji Y, Wang X, Kalicki C, Menta BW, Baumgardner M, Koppel SJ, Weidling IW, Perez-Ortiz J, Wilkins HM, Swerdlow RH. Effects of Microglial Cytokines on Alzheimer's Disease-Related Phenomena. Journal of Alzheimer's Disease : Jad. PMID 30714956 DOI: 10.3233/Jad-180820 |
0.782 |
|
2019 |
Morris JK, McCoin CS, Fuller KNZ, John CS, Wilkins HM, Wang X, Mahnken JD, Swerdlow RH, Thyfault JP. P1-197: Skeletal Muscle Mitochondrial Function In Cognitively Healthy Elderly And Mci Subjects Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.752 |
0.55 |
|
2019 |
Wilkins HM, Menta B, Weidling I, Koppel SJ, Swerdlow RH. P1-196: AMYLOID BETA AND BIOENERGETICS Alzheimer's & Dementia. 15: P312-P312. DOI: 10.1016/J.Jalz.2019.06.751 |
0.761 |
|
2019 |
Vidoni ED, Choi I, Lee P, Clutton J, Becker AM, Sherry E, Bothwell R, Anderson H, Mahnken JD, Wilkins HM, Brooks W, Reed G, Burns JM, Swerdlow RH. P3-008: TRIAL OF OXALOACETATE IN ALZHEIMER'S DISEASE (TOAD): FINAL RESULTS Alzheimer's & Dementia. 15: P927-P927. DOI: 10.1016/J.Jalz.2019.06.3034 |
0.56 |
|
2019 |
Wilkins HM, Wang X, Menta B, Koppel SJ, Bothwell R, Becker AM, Anderson H, Schwartz E, Sherry E, Burns JM, Swerdlow RH. P2-230: BIOENERGETIC BIOMARKERS IN APOE ε4-CARRIER AD SUBJECTS Alzheimer's & Dementia. 15: P667-P668. DOI: 10.1016/J.Jalz.2019.06.2637 |
0.79 |
|
2019 |
Sandberg AA, Manning E, Wilkins HM, Mazzarino R, Minckley T, Qin Y, Patterson D, Linseman D. P2-214: A NOVEL NEUROTOXIC ROLE OF THE APP INTRACELLULAR DOMAIN (AICD) AT THE MITOCHONDRIA, A DISTINCT MECHANISM FROM THAT OF Aβ Alzheimer's & Dementia. 15: P659-P659. DOI: 10.1016/J.Jalz.2019.06.2621 |
0.663 |
|
2019 |
Choi I, Lee P, Vidoni ED, Clutton J, Becker AM, Sherry E, Bothwell R, Anderson H, Mahnken JD, Wilkins HM, Brooks W, Reed G, Burns JM, Swerdlow RH. P2-037: EFFECTS OF OXALOACETATE TREATMENTS ON CEREBRAL ANTIOXIDANT AND NEUROCHEMICAL PROFILE IN PATIENTS WITH ALZHEIMER'S DISEASE USING IN VIVO METABOLIC NEUROIMAGING Alzheimer's & Dementia. 15: P585-P586. DOI: 10.1016/J.Jalz.2019.06.1259 |
0.563 |
|
2018 |
Kumar RP, Ray S, Home P, Saha B, Bhattacharya B, Wilkins HM, Chavan H, Ganguly A, Milano-Foster J, Paul A, Krishnamurthy P, Swerdlow RH, Paul S. Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription. Development (Cambridge, England). PMID 30201685 DOI: 10.1242/Dev.162644 |
0.594 |
|
2018 |
Statland JM, Moore D, Wang Y, Walsh M, Mozaffar T, Elman L, Nations S, Mitsumoto H, Fernandes JA, Saperstein D, Hayat G, Herbelin L, Karam C, Katz J, Wilkins HM, et al. Rasagiline for Amyotrophic Lateral Sclerosis: a Randomized Controlled Trial. Muscle & Nerve. PMID 30192007 DOI: 10.1002/Mus.26335 |
0.463 |
|
2018 |
Brinkley TE, Berger MS, Callahan KE, Fieo RA, Jennings LA, Morris JK, Wilkins HM, Kritchevsky SB. Workshop on Synergies Between Alzheimer's Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29982466 DOI: 10.1093/Gerona/Gly041 |
0.305 |
|
2018 |
Duval N, Sumner WA, Andrianakos AG, Gray JJ, Bouchard RJ, Wilkins HM, Linseman DA. The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord. Frontiers in Cellular Neuroscience. 12: 15. PMID 29440992 DOI: 10.3389/Fncel.2018.00015 |
0.694 |
|
2017 |
Ma E, Chen P, Wilkins HM, Wang T, Swerdlow RH, Chen Q. Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis. Free Radical Biology & Medicine. PMID 28916476 DOI: 10.1016/J.Freeradbiomed.2017.09.008 |
0.536 |
|
2017 |
Winter AN, Ross EK, Daliparthi V, Sumner WA, Kirchhof DM, Manning E, Wilkins HM, Linseman DA. A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione. Oxidative Medicine and Cellular Longevity. 2017: 3103272. PMID 28894506 DOI: 10.1155/2017/3103272 |
0.627 |
|
2017 |
Wang X, Zhang Q, Bao R, Zhang N, Wang Y, Polo-Parada L, Tarim A, Alemifar A, Han X, Wilkins HM, Swerdlow RH, Wang X, Ding S. Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death. Cell Reports. 20: 2184-2200. PMID 28854367 DOI: 10.1016/J.Celrep.2017.08.022 |
0.72 |
|
2017 |
Wilkins HM, Mahnken JD, Welch P, Bothwell R, Koppel S, Jackson RL, Burns JM, Swerdlow RH. A Mitochondrial Biomarker-Based Study of S-Equol in Alzheimer's Disease Subjects: Results of a Single-Arm, Pilot Trial. Journal of Alzheimer's Disease : Jad. PMID 28598847 DOI: 10.3233/Jad-170077 |
0.817 |
|
2017 |
Morris K J, Uy RAZ, Vidoni ED, Wilkins HM, Archer AE, Thyfault JP, Miles JM, Burns JM. Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28550261 DOI: 10.3233/Jad-170148 |
0.409 |
|
2017 |
Hutfles LJ, Wilkins HM, Koppel SJ, Weidling IW, Selfridge JE, Tan E, Thyfault JP, Slawson C, Fenton AW, Zhu H, Swerdlow RH. A Bioenergetics Systems Evaluation of Ketogenic Diet Liver Effects. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. PMID 28514599 DOI: 10.1139/Apnm-2017-0068 |
0.763 |
|
2017 |
Wilkins HM, Weidling IW, Ji Y, Swerdlow RH. Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration. Frontiers in Immunology. 8: 508. PMID 28491064 DOI: 10.3389/Fimmu.2017.00508 |
0.816 |
|
2017 |
Wilkins HM, Koppel SJ, Bothwell R, Mahnken J, Burns JM, Swerdlow RH. Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients. Redox Biology. 12: 828-832. PMID 28448944 DOI: 10.1016/J.Redox.2017.04.010 |
0.796 |
|
2017 |
Winter AN, Ross EK, Wilkins HM, Stankiewicz TR, Wallace T, Miller K, Linseman DA. An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis. Nutritional Neuroscience. 1-13. PMID 28276271 DOI: 10.1080/1028415X.2017.1297023 |
0.779 |
|
2017 |
Swerdlow RH, Koppel S, Weidling I, Hayley C, Ji Y, Wilkins HM. Mitochondria, Cybrids, Aging, and Alzheimer's Disease. Progress in Molecular Biology and Translational Science. 146: 259-302. PMID 28253988 DOI: 10.1016/Bs.Pmbts.2016.12.017 |
0.834 |
|
2017 |
Morris JK, Vidoni ED, Johnson DK, Van Sciver A, Mahnken JD, Honea RA, Wilkins HM, Brooks WM, Billinger SA, Swerdlow RH, Burns JM. Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial. Plos One. 12: e0170547. PMID 28187125 DOI: 10.1371/Journal.Pone.0170547 |
0.532 |
|
2017 |
Wilkins HM, Koppel S, Bothwell R, Mahnken JD, Burns JM, Swerdlow RH. [P3-229]: PLATELET MITOCHONDRIA CYTOCHROME OXIDASE AND CITRATE SYNTHASE IN APOE4-CARRIER AD SUBJECTS Alzheimer's & Dementia. 13: P1026-P1026. DOI: 10.1016/J.Jalz.2017.06.1442 |
0.797 |
|
2016 |
Wilkins HM, Morris JK. New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders. Current Pharmaceutical Design. PMID 28034353 DOI: 10.2174/1381612822666161230144517 |
0.431 |
|
2016 |
Wilkins HM, Koppel SJ, Weidling IW, Roy N, Ryan LN, Stanford JA, Swerdlow RH. Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 27562848 DOI: 10.1007/S11481-016-9704-7 |
0.823 |
|
2016 |
Wilkins HM, Swerdlow RH. Amyloid Precursor Protein Processing and Bioenergetics. Brain Research Bulletin. PMID 27545490 DOI: 10.1016/J.Brainresbull.2016.08.009 |
0.617 |
|
2016 |
Morris JK, Vidoni ED, Wilkins HM, Archer AE, Burns NC, Karcher RT, Graves RS, Swerdlow RH, Thyfault JP, Burns JM. Impaired fasting glucose is associated with increased regional cerebral amyloid. Neurobiology of Aging. 44: 138-42. PMID 27318141 DOI: 10.1016/J.Neurobiolaging.2016.04.017 |
0.564 |
|
2016 |
Wilkins HM, Koppel S, Carl SM, Ramanujan S, Weidling I, Michaelis ML, Michaelis EK, Swerdlow RH. Oxaloacetate Enhances Neuronal Cell Bioenergetic Fluxes and Infrastructure. Journal of Neurochemistry. PMID 26811028 DOI: 10.1111/Jnc.13545 |
0.803 |
|
2016 |
Wilkins HM, Swerdlow RH. Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease. Current Topics in Medicinal Chemistry. 16: 849-57. PMID 26311426 DOI: 10.2174/1568026615666150827095102 |
0.659 |
|
2016 |
Wilkins HM, Weidling I, Carl SM, Ramanujan S, Weber SG, Swerdlow RH. P4-067: Influence of Cell Bioenergetics on App Processing Alzheimer's & Dementia. 12: P1039-P1039. DOI: 10.1016/J.Jalz.2016.06.2157 |
0.784 |
|
2016 |
Wilkins HM, Welch P, Koppel S, Bothwell R, Mahnken JD, Burns JM, Swerdlow RH. P3-026: Trial of S-Equol in Alzheimer’s Disease (SEAD) Alzheimer's & Dementia. 12: P827-P827. DOI: 10.1016/J.Jalz.2016.06.1683 |
0.758 |
|
2016 |
Wilkins HM, Koppel S, Roy N, Ryan L, Stanford JA, Swerdlow RH. P2-128: Mitochondria and Mitochondrial DNA Induce Neuroinflammation and Alter app Homeostasis Alzheimer's & Dementia. 12: P660-P661. DOI: 10.1016/J.Jalz.2016.06.1498 |
0.817 |
|
2016 |
Morris JK, Vidoni ED, Wilkins HM, Swerdlow RH, Burns JM. P2-094: Relationship Between Apolipoprotein E4 Genotype and Whole Body Aerobic Capacity Alzheimer's & Dementia. 12: P646-P647. DOI: 10.1016/J.Jalz.2016.06.1299 |
0.497 |
|
2015 |
Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, ... ... Wilkins H, et al. A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 25832828 DOI: 10.3109/21678421.2015.1026826 |
0.547 |
|
2015 |
Wilkins HM, Swerdlow RH. TNFα in cerebral ischemia: another stroke against you? Journal of Neurochemistry. 132: 369-72. PMID 25656781 DOI: 10.1111/Jnc.13028 |
0.47 |
|
2015 |
Wilkins HM, Carl SM, Weber SG, Ramanujan SA, Festoff BW, Linseman DA, Swerdlow RH. Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells. Journal of Alzheimer's Disease : Jad. 45: 305-18. PMID 25537010 DOI: 10.3233/Jad-142334 |
0.787 |
|
2015 |
Selfridge JE, Wilkins HM, E L, Carl SM, Koppel S, Funk E, Fields T, Lu J, Tang EP, Slawson C, Wang W, Zhu H, Swerdlow RH. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. Journal of Bioenergetics and Biomembranes. 47: 1-11. PMID 25104046 DOI: 10.1007/S10863-014-9570-Z |
0.775 |
|
2015 |
Wilkins HM, Carl SM, Ramanujan S, Weber SG, Swerdlow RH. P3-023: Influence of mitochondrial function and cell bioenergetics on app processing Alzheimer's & Dementia. 11: P628-P628. DOI: 10.1016/J.Jalz.2015.06.889 |
0.618 |
|
2015 |
Wilkins HM, Roy N, Stanford JA, Swerdlow RH. P4-024: Injecting mitochondria into mouse hippocampi induces neuroinflammation and raises app expression Alzheimer's & Dementia. 11: P774-P775. DOI: 10.1016/J.Jalz.2015.06.1728 |
0.803 |
|
2014 |
Ross EK, Winter AN, Wilkins HM, Sumner WA, Duval N, Patterson D, Linseman DA. A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis. Antioxidants (Basel, Switzerland). 3: 843-65. PMID 26785244 DOI: 10.3390/Antiox3040843 |
0.612 |
|
2014 |
Wilkins HM, Carl SM, Swerdlow RH. Cytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathies. Redox Biology. 2: 619-631. PMID 25460729 DOI: 10.1016/J.Redox.2014.03.006 |
0.564 |
|
2014 |
Wilkins HM, Carl SM, Greenlief AC, Festoff BW, Swerdlow RH. Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connection. Frontiers in Aging Neuroscience. 6: 311. PMID 25426068 DOI: 10.3389/Fnagi.2014.00311 |
0.601 |
|
2014 |
Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. Human Molecular Genetics. 23: 6528-41. PMID 25027327 DOI: 10.1093/Hmg/Ddu371 |
0.796 |
|
2014 |
Wilkins HM, Brock S, Gray JJ, Linseman DA. Stable over-expression of the 2-oxoglutarate carrier enhances neuronal cell resistance to oxidative stress via Bcl-2-dependent mitochondrial GSH transport. Journal of Neurochemistry. 130: 75-86. PMID 24606213 DOI: 10.1111/Jnc.12709 |
0.756 |
|
2014 |
Wilkins HM, Swerdlow RH, Carl S, Harris J, Lu J, Koppel S, E L, Selfridge E, Hutfles L, Roy N, Burns JM, Brooks WM, Michaelis M, Michaelis E. P4-199: IMPACT OF OXALOACETATE ON BRAIN BIOENERGETIC INFRASTRUCTURES, NEUROGENESIS, AND INFLAMMATION Alzheimer's & Dementia. 10: P861-P861. DOI: 10.1016/J.Jalz.2014.05.1716 |
0.765 |
|
2013 |
Wilkins HM, Kirchhof D, Manning E, Joseph JW, Linseman DA. Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress. The Journal of Biological Chemistry. 288: 5091-101. PMID 23283974 DOI: 10.1074/Jbc.M112.405738 |
0.68 |
|
2013 |
Wilkins H, Marquardt K, Linseman D. P2-007: Apoptosis induced by overexpression of APP requires its localization to mitochondria Alzheimer's & Dementia. 9: P348-P348. DOI: 10.1016/J.Jalz.2013.05.649 |
0.656 |
|
2012 |
Bartley MG, Marquardt K, Kirchhof D, Wilkins HM, Patterson D, Linseman DA. Overexpression of amyloid-β protein precursor induces mitochondrial oxidative stress and activates the intrinsic apoptotic cascade. Journal of Alzheimer's Disease : Jad. 28: 855-68. PMID 22133762 DOI: 10.3233/Jad-2011-111172 |
0.705 |
|
2012 |
Wilkins HM, Marquardt K, Lash LH, Linseman DA. Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione. Free Radical Biology & Medicine. 52: 410-9. PMID 22115789 DOI: 10.1016/J.Freeradbiomed.2011.10.495 |
0.687 |
|
2011 |
Harbison RA, Ryan KR, Wilkins HM, Schroeder EK, Loucks FA, Bouchard RJ, Linseman DA. Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons. Neurotoxicity Research. 19: 374-88. PMID 20333497 DOI: 10.1007/S12640-010-9172-4 |
0.638 |
|
2010 |
Kelsey NA, Wilkins HM, Linseman DA. Nutraceutical antioxidants as novel neuroprotective agents. Molecules (Basel, Switzerland). 15: 7792-814. PMID 21060289 DOI: 10.3390/Molecules15117792 |
0.599 |
|
2006 |
Wilkins HM, Wang X, Koppel SJ, Bothwell R, Becker AM, Anderson H, Sherry E, Burns JM, Swerdlow RH. P2-282: PLATELET AND LYMPHOCYTE MITOCHONDRIAL BIOMARKERS IN APOE ε4-CARRIER AD SUBJECTS Alzheimer's & Dementia. 14: P788-P789. DOI: 10.1016/J.Jalz.2018.06.971 |
0.821 |
|
2006 |
Koppel SJ, Wilkins HM, Weidling I, Swerdlow RH. P2-149: EFFECT OF β-HYDROXYBUTYRATE ON NEURONS AND ASTROCYTES Alzheimer's & Dementia. 14: P725-P725. DOI: 10.1016/J.Jalz.2018.06.835 |
0.774 |
|
2006 |
Vidoni ED, Clutton J, Becker AM, Sherry E, Bothwell R, Mahnken JD, Wilkins HM, Lee P, Choi I, Brooks W, Reed G, Burns JM, Swerdlow RH. P4-009: TRIAL OF OXALOACETATE IN ALZHEIMER'S DISEASE (TOAD): INTERIM FDG PET ANALYSIS Alzheimer's & Dementia. 14: P1435-P1436. DOI: 10.1016/J.Jalz.2018.06.2411 |
0.525 |
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2006 |
Wilkins HM, Weidling I, Swerdlow RH. P1-227: MITOCHONDRIAL MEMBRANE POTENTIAL INFLUENCE ON PROCESSING AND LOCALIZATION OF APP Alzheimer's & Dementia. 14: P365-P365. DOI: 10.1016/J.Jalz.2018.06.232 |
0.803 |
|
2006 |
Michaelis EK, Pal R, Schoneich C, Wilkins HM, Swerdlow RH, Michaelis ML. P1-225: PROTECTION AGAINST AB-INDUCED NEURONAL DAMAGE BY AN HSP90 C-TERMINAL MODULATOR: IMPORTANCE OF PYRUVATE DEHYDROGENASE KINASE Alzheimer's & Dementia. 14: P364-P365. DOI: 10.1016/J.Jalz.2018.06.230 |
0.52 |
|
2006 |
Morris JK, John CS, Wilkins HM, Wang X, Weidling I, Thyfault JP, Vidoni ED, Swerdlow RH, Burns JM. P3-231: ALZHEIMER'S DISEASE SUBJECTS EXHIBIT IMPAIRED SYSTEMIC GLUCOSE METABOLISM FOLLOWING A MIXED MEAL Alzheimer's & Dementia. 14: P1159-P1160. DOI: 10.1016/J.Jalz.2018.06.1590 |
0.788 |
|
2006 |
Weidling I, Wilkins HM, Koppel SJ, Wang X, Gamblin TC, Swerdlow RH. P3-186: RESPIRATORY CHAIN INCOMPETENCE ALTERS TAU HOMEOSTASIS Alzheimer's & Dementia. 14: P1138-P1138. DOI: 10.1016/J.Jalz.2018.06.1544 |
0.785 |
|
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