Adam C. Naj, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Epidemiology, Public Health, Genetics

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Naj A, Blue EE, et al. Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project. Medrxiv : the Preprint Server For Health Sciences. PMID 37693521 DOI: 10.1101/2023.09.01.23294953  0.45
2023 Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Naj AC, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311  0.449
2023 Bai H, Naj AC, Benchek P, Dumitrescu L, Hohman T, Hamilton-Nelson K, Kallianpur AR, Griswold AJ, Vardarajan B, Martin ER, Beecham GW, Below JE, Schellenberg G, Mayeux R, Farrer L, et al. A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37051669 DOI: 10.1002/alz.13050  0.337
2023 de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Naj AC, et al. Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 14: 716. PMID 36759603 DOI: 10.1038/s41467-023-36192-x  0.315
2023 Li YJ, Nuytemans K, La JO, Jiang R, Slifer SH, Sun S, Naj A, Gao XR, Martin ER. Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36738287 DOI: 10.1002/alz.12927  0.422
2022 Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S, Mayeux RP, Farrer LA, Cuccaro ML, Vance JM, Griswold AJ, et al. Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36539198 DOI: 10.1002/alz.12865  0.339
2022 Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N, Norsworthy PJ, Dols-Icardo O, Hummerich H, Kawalia A, Amouyel P, ... ... Naj AC, et al. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. Nature Genetics. PMID 36411364 DOI: 10.1038/s41588-022-01208-7  0.443
2022 Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW, Martin ER, Naj AC, Ertekin-Taner N, Golde TE, Hood L, et al. Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. Scientific Reports. 12: 6117. PMID 35413975 DOI: 10.1038/s41598-022-09825-2  0.445
2022 Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z  0.422
2022 Jin B, Capra JA, Benchek P, Wheeler NR, Naj AC, Hamilton-Nelson KL, Farrell JJ, Leung YY, Kunkle BW, Vardarajan BN, Schellenberg GD, Mayeux R, Wang LS, Farrer LA, Pericak-Vance M, et al. An association test of the spatial distribution of rare missense variants within protein structures identify Alzheimer's disease-related patterns. Genome Research. PMID 35210353 DOI: 10.1101/gr.276069.121  0.392
2022 Kuksa PP, Liu CL, Fu W, Qu L, Zhao Y, Katanic Z, Clark K, Kuzma AB, Ho PC, Tzeng KT, Valladares O, Chou SY, Naj AC, Schellenberg GD, Wang LS, et al. Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35068457 DOI: 10.3233/JAD-215055  0.476
2021 Chen HH, Petty LE, Sha J, Zhao Y, Kuzma A, Valladares O, Bush W, Naj AC, Gamazon ER, Below JE. Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci. Translational Psychiatry. 11: 618. PMID 34873149 DOI: 10.1038/s41398-021-01677-0  0.411
2021 de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Naj AC, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8  0.417
2020 Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, et al. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. Jama Neurology. PMID 33074286 DOI: 10.1001/jamaneurol.2020.3536  0.401
2020 Vergouw LJM, Melhem S, Donker Kaat L, Chiu WZ, Kuipers DJS, Breedveld G, Boon AJW, Wang LS, Naj AC, Mlynarksi E, Cantwell L, Quadri M, Ross OA, Dickson DW, Schellenberg GD, et al. LRP10 variants in progressive supranuclear palsy. Neurobiology of Aging. PMID 32527607 DOI: 10.1016/J.Neurobiolaging.2020.04.016  0.377
2019 Chen HH, Petty LE, Bush W, Naj AC, Below JE. GWAS and Beyond: Using Omics Approaches to Interpret SNP Associations. Current Genetic Medicine Reports. 7: 30-40. PMID 33312764 DOI: 10.1007/S40142-019-0159-Z  0.473
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.356
2019 Naj AC. Genotype Imputation in Genome-Wide Association Studies. Current Protocols in Human Genetics. 102: e84. PMID 31216114 DOI: 10.1002/Cphg.84  0.392
2019 Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, et al. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. Jama Neurology. PMID 31180460 DOI: 10.1001/Jamaneurol.2019.1456  0.577
2019 Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, et al. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. e12964. PMID 31144443 DOI: 10.1111/Acel.12964  0.499
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.443
2019 Hu Y, Li M, Lu Q, Weng H, Wang J, Zekavat SM, Yu Z, Li B, Gu J, Muchnik S, Shi Y, Kunkle BW, Mukherjee S, Natarajan P, Naj A, et al. A statistical framework for cross-tissue transcriptome-wide association analysis. Nature Genetics. PMID 30804563 DOI: 10.1038/S41588-019-0345-7  0.322
2019 Mena PR, Kunkle BW, Faber K, Celis K, Adams LD, Foroud TM, Reyes-Dumeyer D, Kuzma AB, Naj A, Martin ER, Dalgard C, Schellenberg GD, Wang L, Vance JM, Cuccaro ML, et al. P2-151: THE ALZHEIMER'S DISEASE SEQUENCING PROJECT - FOLLOW UP STUDY (ADSP-FUS): INCREASING ETHNIC DIVERSITY IN ALZHEIMER'S GENETICS RESEARCH Alzheimer's & Dementia. 15: P634-P634. DOI: 10.1016/J.Jalz.2019.06.4961  0.5
2019 Naj A, Sha J, Leonenko G, Chen Y, Chouraki V, Leber M, Sims R, Grenier-Boley B, Bis JC, Zhao Y, Kuzma AB, Kunkle BW, Karamujić-Čomić H, Lee SJVD, Bellenguez C, et al. O2‐10‐06: Genome‐Wide Meta‐Analysis Of Late‐Onset Alzheimer'S Disease Using Rare Variant Imputation In 64,859 Subjects Identifies Risk Loci With Roles In Innate Immunity And Cardiovascular Traits: The International Genomics Of Alzheimer'S Project (Igap) Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4510  0.506
2019 Vardarajan BN, Jaworski J, Beecham GW, Barral S, Reyes-Dumeyer D, Medrano M, Lantigua R, Leung YY, Wang L, Naj A, Martin ER, Haines JL, Bush WS, Farrer LA, Schellenberg GD, et al. P4-097: Rare Variants In Familial Late-Onset Alzheimer'S Disease Identified From Large Scale Whole Genome Sequencing Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3757  0.508
2019 Kunkle BW, Hamilton-Nelson KL, Gomez L, Jean-Francois M, Naj A, Wang L, Kuzma AB, Beecham GW, Bush WS, Hohman TJ, Vardarajan BN, Wang L, Mayeux R, Haines JL, Farrer LA, et al. P4-094: Exome-Wide Analysis Identifies Novel Sex-Specific Candidate Genes For Alzheimer Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3754  0.494
2019 Vogel B, Kuzma AB, Valladares O, Greenfest-Allen E, Gangadharan P, Zhao Y, Katanic Z, Qu L, Lin H, Moon MK, Leung YY, Issen H, Klamann C, Naj A, Stoeckert CJ, et al. P4-090: NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE (NIAGADS): UPDATE 2019 Alzheimer's & Dementia. 15: P1309-P1309. DOI: 10.1016/J.Jalz.2019.06.3750  0.483
2019 Li Y, Slifer SH, Schmidt MA, Naj A, Gao XR, Martin ER. P3-123: Identification Of Genes Modifying Age-At-Onset Of Alzheimer'S Disease In The Alzheimer'S Disease Genetics Consortium (Adgc) Cohorts Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3151  0.544
2019 Wang L, Leung YY, Valladares O, Chou Y, Kuzma AB, Gangadharan P, Cantwell LB, Qu L, Lin H, Malamon JS, Zhao Y, Martin ER, Naj A, Schellenberg GD, Sequencing AD. P2-134: Genome Center For Alzheimer'S Disease Whole Exome (Wes) And Whole Genome Sequencing (Wgs) Data Update Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2541  0.472
2018 Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, et al. Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease. Neurology. Genetics. 4: e286. PMID 30569016 DOI: 10.1212/Nxg.0000000000000286  0.482
2018 Guerreiro R, Orme T, Naj AC, Kuzma AB, Schellenberg GD, Bras J. Is APOE ε4 required for Alzheimer's disease to develop in TREM2 p.R47H variant carriers? Neuropathology and Applied Neurobiology. PMID 30229991 DOI: 10.1111/Nan.12517  0.528
2018 McMillan CT, Lee EB, Jefferson-George K, Naj A, Van Deerlin VM, Trojanowski JQ, Wolk DA. Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance? Annals of Clinical and Translational Neurology. 5: 927-934. PMID 30128317 DOI: 10.1002/Acn3.581  0.469
2018 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Naj AC, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7  0.535
2018 Naj AC, Lin H, Vardarajan BN, White S, Lancour D, Ma Y, Schmidt M, Sun F, Butkiewicz M, Bush WS, Kunkle BW, Malamon J, Amin N, Choi SH, Hamilton-Nelson KL, et al. Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project. Genomics. PMID 29857119 DOI: 10.1016/J.Ygeno.2018.05.004  0.426
2018 Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A, Thornton T, DeStefano A, Martin E, Wang LS, Brown L, et al. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. 5: 406-417. PMID 29688227 DOI: 10.1002/Acn3.537  0.531
2018 Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GC, Crovella M, Farrer LA, Kasif S. One for all and all for One: Improving replication of genetic studies through network diffusion. Plos Genetics. 14: e1007306. PMID 29684019 DOI: 10.1371/Journal.Pgen.1007306  0.457
2018 Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, ... ... Naj A, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503  0.541
2018 Teslovich TM, Kim DS, Yin X, Stancáková A, Jackson AU, Wielscher M, Naj A, Perry JRB, Huyghe JR, Stringham HM, Davis JP, Raulerson CK, Welch RP, Fuchsberger C, Locke AE, et al. Identification of seven novel loci associated with amino acid levels using single variant and gene-based tests in 8,545 Finnish men from the METSIM study. Human Molecular Genetics. PMID 29481666 DOI: 10.1093/Hmg/Ddy067  0.378
2018 Khan RR, Altmann A, Napolioni V, Kim Y, Guerreiro R, Bras JT, Carmona S, Pereira M, Santana I, Hardy J, Mead S, Cruchaga C, Fernandez MV, Holstege H, Flier WMVd, ... ... Naj AC, et al. P4-240: Stop-Gain Variant In Microglia-Expressed Gene Gmip Is Associated With Early-Onset Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.061  0.52
2018 Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj AC, Thornton TA, Destefano AL, Martin ER, Wang L, Brown L, et al. P1-156: Gene-Based Analyses In Whole Genome Sequencing Of Familial Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.160  0.515
2018 Kuzma AB, Faber K, Salerno WJ, Leung YY, Cantwell LB, Gupta N, Fulton R, Valladares O, Vogel B, Appelbaum E, Choi SH, Hamilton-Nelson KL, Zhao Y, Muzny D, Qu L, ... ... Naj AC, et al. P1-149: The Alzheimer'S Disease Sequencing Project (Adsp) Data Update 2018 Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.152  0.468
2018 Zhang X, Zhou TJ, Farrell J, Chung J, Naj AC, Lunetta KL, Farrer LA. P3-108: Identification Of Mitochondrial Variants Associated With Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1465  0.501
2017 Beecham GW, Bis JC, Martin ER, Choi SH, DeStefano AL, van Duijn CM, Fornage M, Gabriel SB, Koboldt DC, Larson DE, Naj AC, Psaty BM, Salerno W, Bush WS, Foroud TM, et al. The Alzheimer's Disease Sequencing Project: Study design and sample selection. Neurology. Genetics. 3: e194. PMID 29184913 DOI: 10.1212/Nxg.0000000000000194  0.536
2017 Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S, Soininen H, Hiltunen M, Ramirez A, Scherer M, Farrer LA, et al. Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. Plos One. 12: e0185777. PMID 28985224 DOI: 10.1371/Journal.Pone.0185777  0.497
2017 Naj AC, Beaty TH. Detecting Familial Aggregation. Methods in Molecular Biology (Clifton, N.J.). 1666: 133-169. PMID 28980245 DOI: 10.1007/978-1-4939-7274-6_8  0.341
2017 Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR, Wang LS, Farrer LA, Reitz C, Haines JL, Beecham GW, et al. Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport. Jama Neurology. PMID 28738127 DOI: 10.1001/Jamaneurol.2017.1518  0.487
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.548
2017 Kunkle BW, Carney RM, Kohli MA, Naj AC, Hamilton-Nelson KL, Whitehead PL, Wang L, Lang R, Cuccaro ML, Vance JM, Byrd GS, Beecham GW, Gilbert JR, Martin ER, Haines JL, et al. Targeted sequencing of ABCA7 identifies splicing, stop-gain and intronic risk variants for Alzheimer disease. Neuroscience Letters. PMID 28400126 DOI: 10.1016/J.Neulet.2017.04.014  0.489
2017 Mukherjee S, Russell JC, Carr DT, Burgess JD, Younkin MA, Serie D, Boehme KL, Kauwe JS, Naj AC, Fardo DW, Dickson DW, Montine TJ, Ertekin-Taner N, Kaeberlein MR, Crane PK. Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28242297 DOI: 10.1016/J.Jalz.2017.01.016  0.507
2017 Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, ... ... Naj A, et al. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28183528 DOI: 10.1016/J.Jalz.2016.12.012  0.54
2017 Naj AC, Schellenberg GD. Genomic variants, genes, and pathways of Alzheimer's disease: An overview. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 174: 5-26. PMID 27943641 DOI: 10.1002/Ajmg.B.32499  0.539
2017 Naj AC, Below J, Zhao Y, Chen H, Lee SJvd, Hamilton-Nelson KL, Petty L, Kunkle BW, Kuzma AB, Valladares O, Reitz C, Beecham GW, Martin ER, Wang L, Haines JL, et al. Genome-Wide Rare Variant Imputation And Tissue-Specific Transcriptomic Analysis Identify Novel Rare Variant Candidate Loci In Late-Onset Alzheimer’S Disease: The Alzheimer’S Disease Genetics Consortium Alzheimers & Dementia. 13: 189. DOI: 10.1016/J.Jalz.2017.07.045  0.506
2017 Valladares O, Kuzma AB, Greenfest-Allen E, Childress DM, Cweibel R, Gangadharan P, Lin H, Qu L, Leung YY, Naj AC, Stoeckert CJ, Schellenberg GD, Wang L. [P3-097]: NIA GENETICS OF ALZHEIMER's DISEASE DATA STORAGE SITE (NIAGADS): 2017 Alzheimer's & Dementia. 13: P971-P971. DOI: 10.1016/J.Jalz.2017.06.1307  0.482
2017 Kuzma AB, Faber K, Salerno W, Leung YY, Cantwell LB, Feolo M, Stine A, Gupta N, Fulton R, Valladares O, Cweibel R, Appelbaum E, Choi SH, Hamilton-Nelson KL, Lin H, ... ... Naj AC, et al. [P3-090]: THE ALZHEIMER's DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2017 Alzheimer's & Dementia. 13: P968-P968. DOI: 10.1016/J.Jalz.2017.06.1300  0.468
2017 Malamon JS, Naj AC. P3-081: Post-Variant Calling Quality Control (Qc) Pipeline And Multi-Pipeline Genotype Consensus Caller For Large-Scale Whole Genome And Whole Exome Sequencing Studies Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1275  0.357
2016 Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, et al. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. Plos Genetics. 12: e1006327. PMID 27764101 DOI: 10.1371/Journal.Pgen.1006327  0.475
2016 Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK, et al. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable. Neurobiology of Aging. 41: 115-21. PMID 27103524 DOI: 10.1016/J.Neurobiolaging.2016.02.015  0.413
2016 Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, et al. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiology of Aging. 38: 141-50. PMID 26827652 DOI: 10.1016/J.Neurobiolaging.2015.10.031  0.513
2016 Kuzma A, Valladares O, Cweibel R, Greenfest-Allen E, Childress DM, Malamon J, Gangadharan P, Zhao Y, Qu L, Leung YY, Naj AC, Stoeckert CJ, Schellenberg GD, Wang L. NIAGADS: The NIA Genetics of Alzheimer's Disease Data Storage Site Alzheimer's & Dementia. 12: 1200-1203. DOI: 10.1016/J.Jalz.2016.08.018  0.519
2016 Jian X, Bis JC, Kunkle BW, Hamilton KL, Beecham GW, Bush WS, Salerno W, Lancour D, Ma Y, Chen Y, DeStefano AL, Dupuis J, Boerwinkle E, Schellenberg GD, Seshadri S, ... Naj AC, et al. Rare Deleterious And Loss-Of-Function Variants In Oprl1 And Gas2L2 Contribute To The Risk Of Late-Onset Alzheimer’S Disease: Alzheimer’S Disease Sequencing Project Case-Control Study Alzheimers & Dementia. 12: 163. DOI: 10.1016/J.Jalz.2016.06.765  0.451
2016 Naj AC. Alzheimer'S Disease Sequencing Project: Case-Control Analyses Alzheimers & Dementia. 12: 322. DOI: 10.1016/J.Jalz.2016.06.584  0.451
2016 Naj AC, Zhao Y, Lee SJvd, Hamilton KL, Kunkle BW, Partch AB, Valladares O, Beecham GW, Martin ER, Wang L, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. High-Resolution Imputation In Genome-Wide Association Studies Of Late-Onset Alzheimer'S Disease Identifies Novel Rare Variant Associations Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.308  0.536
2016 Kunkle BW, Vardarajan BN, Naj AC, Cukier HN, Dykxhoorn DM, Rolati S, Whitehead PL, Carney RM, Cuccaro ML, Vance JM, Genetics Consortium AD, Farrer LA, Haines JL, Schellenberg GD, Martin ER, et al. O1-03-03: Identification of Novel Candidate Genes for Early-Onset Alzheimer's Disease Through Integrated Whole-Exome Sequencing and Exome Chip Array Association Analysis Alzheimer's & Dementia. 12: P177-P178. DOI: 10.1016/J.Jalz.2016.06.306  0.48
2016 Marcora E, Renton AE, Beecham GW, Boerwinkle E, Cantwell L, Cruchaga C, Cweibel R, Felsenfeld A, Fornage M, Kapoor M, Kauwe K, Khaladkar M, Kobolt D, Ma Y, Mayeux R, ... ... Naj AC, et al. F1-01-02: Alzheimer's Disease Sequencing Project: Search for Alzheimer's Disease Resilience Genes That May Modify Disease Susceptibility in Specific Apoe Genotype Backgrounds Alzheimer's & Dementia. 12: P162-P163. DOI: 10.1016/J.Jalz.2016.06.272  0.515
2016 Gangadharan P, Partch AB, Valladares O, Greenfest-Allen E, Childress DM, Cweibel R, Malamon J, Lin H, Zhao Y, Khaladkar M, Naj AC, Stoeckert CJ, Schellenberg GD, Wang L. P3-093: NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS): 2016 Update Alzheimer's & Dementia. 12: P855-P856. DOI: 10.1016/J.Jalz.2016.06.1752  0.404
2015 Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, et al. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. Jama Neurology. PMID 26366463 DOI: 10.1001/Jamaneurol.2015.1700  0.498
2015 Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, et al. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26092349 DOI: 10.1016/J.Jalz.2015.02.012  0.509
2015 Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, et al. A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry. PMID 25778476 DOI: 10.1038/Mp.2015.23  0.492
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.495
2015 Nelson PT, Wang WX, Partch AB, Monsell SE, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang LS, Kukull WA, Fardo DW. Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology. Journal of Neuropathology and Experimental Neurology. 74: 75-84. PMID 25470345 DOI: 10.1097/Nen.0000000000000151  0.439
2015 Sims R, Lee SJvd, Naj AC, Vronskaya M, Badarinarayan N. Characterizing missing heritability of late-onset Alzheimer’s disease: An exome array study Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.08.026  0.443
2015 Mukherjee S, Boehme KL, Naj AC, Fardo DW, Kauwe J, Manly JJ, Montine TJ, Crane PK. Integrating human protein-protein interaction network with results from gwas in whites and african-americans identifies common genes underlying late-onset Alzheimer’s disease Alzheimers & Dementia. 11: 299. DOI: 10.1016/J.Jalz.2015.07.413  0.337
2015 Wang W, Lin C, Partch AB, Valladares O, Cantwell L, Naj AC, Wang L, Schellenberg GD. Multiple deletion copy number variants (CNVs) are associated with late-onset Alzheimer's disease: The Alzheimer’s disease genetics consortium Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.263  0.557
2015 Tang M, Kramer C, Xu G, Hawk M, Hwang Y, Lin C, Kuksa P, Wang W, Dombroski BA, Naj AC, Wang L, Schellenberg GD. Prediction of late-onset Alzheimer’s disease-associated enhancer elements Alzheimers & Dementia. 11: 336. DOI: 10.1016/J.Jalz.2015.06.197  0.371
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.505
2014 Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, et al. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Plos Genetics. 10: e1004606. PMID 25188341 DOI: 10.1371/Journal.Pgen.1004606  0.497
2014 Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, ... ... Naj AC, et al. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Human Molecular Genetics. 23: 6644-58. PMID 25027320 DOI: 10.1093/Hmg/Ddu372  0.495
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661  0.548
2014 Carney RM, Kohli MA, Kunkle BW, Naj AC, Gilbert JR, Züchner S, Pericak-Vance MA. Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 360-5. PMID 23727082 DOI: 10.1016/J.Jalz.2013.02.011  0.411
2014 Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 45-52. PMID 23535033 DOI: 10.1016/J.Jalz.2013.01.008  0.459
2014 Pericak-Vance M, Reitz C, Kunkle BW, Vardarajan BN, Kohli MA, Naj AC, Whitehead PL, Perry W, Martin E, Beecham G, Gilbert J, Farrer LA, Haines J, Schellenberg GD, Mayeux R. P2-131: WHOLE-EXOME SEQUENCING OF HISPANIC EARLY-ONSET ALZHEIMER DISEASE FAMILIES IDENTIFIES RARE VARIANTS IN MULTIPLE ALZHEIMER'S-RELATED GENES Alzheimer's & Dementia. 10: P518-P519. DOI: 10.1016/J.Jalz.2014.05.806  0.544
2014 Naj AC, Cruchaga C, Kunkle BW, Mukherjee S, Graham R, Wang L, Behrens T, Mayeux R, Haines J, Farrer LA, Pericak-Vance M, Schellenberg GD. Exome Array Analysis Identifies Novel Risk Variants For Alzheimer'S Disease With Onset Before 65 Years Alzheimers & Dementia. 10: 319. DOI: 10.1016/J.Jalz.2014.05.280  0.504
2014 Mukherjee S, Kaeberlein M, Kauwe J, Naj AC, Crane P. A Systems-Biology Approach To Identify Candidate Genes For Alzheimer'S Disease By Integrating Protein-Protein Interaction Network And Subsequent In Vivo Validation Of Candidate Genes Using A C. Elegans Model Of Ab Toxicity Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.499  0.367
2014 Lee SJvd, Naj A, Duijn Cv, Schellenberg GD, Jakobsdottir J, Williams J, Wang L, Vronskaya M, Amouyel P, Sims R, Seshadri S. Exome Chip Meta-Analysis Of Alzheimer'S Disease In The Igap Consortium Alzheimers & Dementia. 10: 245. DOI: 10.1016/J.Jalz.2014.04.374  0.507
2014 Kunkle BW, Naj AC, Hamilton-Nelson K, Perry WR, Partch A, Valladares O, Chung J, Jun G, Schmidt M, Beecham G, Wang L, Martin E, Mayeux R, Haines J, Farrer LA, et al. Low-Frequency Variant Imputation Identifies Novel Disease-Associated Loci In A Genome-Wide Association Study Of Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 10: 135. DOI: 10.1016/J.Jalz.2014.04.076  0.55
2013 Lin CF, Naj AC, Wang LS. Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 79: Unit 1.27.. PMID 24510649 DOI: 10.1002/0471142905.Hg0127S79  0.42
2013 Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, Lee VM, Trojanowski JQ, Devlin B, Schellenberg GD. The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease. Acta Neuropathologica Communications. 1: 31. PMID 24252572 DOI: 10.1186/2051-5960-1-31  0.463
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802  0.566
2013 Naj AC, Scott WK, Courtenay MD, Cade WH, Schwartz SG, Kovach JL, Agarwal A, Wang G, Haines JL, Pericak-Vance MA. Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. Annals of Human Genetics. 77: 215-31. PMID 23577725 DOI: 10.1111/Ahg.12011  0.381
2013 Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. Jama. 309: 1483-92. PMID 23571587 DOI: 10.1001/Jama.2013.2973  0.581
2013 Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP, Buitendijk GH, Sim X, Weeks DE, Guymer RH, ... ... Naj AC, et al. Seven new loci associated with age-related macular degeneration. Nature Genetics. 45: 433-9, 439e1-2. PMID 23455636 DOI: 10.1038/Ng.2578  0.427
2013 Velez Edwards DR, Naj AC, Monda K, North KE, Neuhouser M, Magvanjav O, Kusimo I, Vitolins MZ, Manson JE, O'Sullivan MJ, Rampersaud E, Edwards TL. Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Human Genetics. 132: 323-36. PMID 23192594 DOI: 10.1007/S00439-012-1246-3  0.32
2013 Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE, Lang R, Beecham G, Martin ER, Gilbert J, Benatar M, et al. Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians. Neurobiology of Aging. 34: 1519.e5-12. PMID 23107433 DOI: 10.1016/J.Neurobiolaging.2012.10.003  0.496
2013 Pericak-Vance M, Kunkle B, Kholi M, Naj A, Perry W, Hamilton K, Whitehead PL, Levin B, Carney R, Crocco E, Wright C, Beecham G, Martin E, Wang L, Gilbert J, et al. P3-021: Variant-domain mapping in confirmed late-onset Alzheimer disease (LOAD) loci identifies multiple genomic regions with potentially functional variants Alzheimer's & Dementia. 9: P557-P557. DOI: 10.1016/J.Jalz.2013.05.1090  0.477
2013 Trittschuh E, Mukherjee S, Thornton T, Fardo D, Waterston L, Crane P, Mez J, Sherva R, Kauwe J, Naj A, Beecham G, Gross A, Saykin A, Green R. P3-003: Genome-wide SNP analysis finds executive-prominent late-onset Alzheimer's disease is highly heritable Alzheimer's & Dementia. 9: P550-P551. DOI: 10.1016/J.Jalz.2013.05.1072  0.467
2013 Mukherjee S, Thornton T, Naj A, Kim S, Kauwe J, Fardo D, Valladares O, Wijsman E, Schellenberg G, Crane P. GWAS of the joint ADGC data set identifies novel common variants associated with late-onset Alzheimer's disease Alzheimers & Dementia. 9: 550. DOI: 10.1016/J.Jalz.2013.05.1071  0.528
2013 Beecham G, Hamilton-Nelson K, Naj A, Wang L, Martin E, Mayeux R, Haines J, Farrer L, Schellenberg G, Pericak-Vance M, Montine T. O4-06-04: Late-onset Alzheimer's disease neuropathology genomic screen identifies novel loci for neuritic plaque and other Alzheimer's neuropathology features Alzheimer's & Dementia. 9: P693-P693. DOI: 10.1016/J.Jalz.2013.04.368  0.494
2013 Kohli M, Kunkle B, Naj A, Carney RM, Hamilton-Nelson K, Rolati S, Whitehead PL, Gilbert J, Martin E, Beecham G, Wang L, Mayeux R, Haines J, Farrer L, Schellenberg G, et al. The identification of rare variants in late-onset Alzheimer’s disease using extended families Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.239  0.429
2013 Naj A, Cruchaga C, Kunkle B, Mukherjee S, Graham R, Behrens T, Mayeux R, Haines J, Farrer L, Pericak-Vance M, Schellenberg G, Wang L. Exome array analysis identifies novel risk variants for non-familial early-onset Alzheimer’s disease Alzheimers & Dementia. 9: 517. DOI: 10.1016/J.Jalz.2013.04.237  0.428
2013 Naj AC, Carney RM, Hahn SE, Slifer MA, Haines JL, Pericak-Vance MA. Genetics of alzheimer disease Emery and Rimoin's Principles and Practice of Medical Genetics. 1-20. DOI: 10.1016/B978-0-12-383834-6.00116-6  0.398
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Naj AC, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.346
2012 Manichaikul A, Naj AC, Herrington D, Post W, Rich SS, Rodriguez A. Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1991-9. PMID 22628436 DOI: 10.1161/Atvbaha.112.249714  0.365
2012 Naj AC, Park YS, Beaty TH. Detecting familial aggregation. Methods in Molecular Biology (Clifton, N.J.). 850: 119-50. PMID 22307697 DOI: 10.1007/978-1-61779-555-8_8  0.45
2012 Cai G, Atzmon G, Naj AC, Beecham GW, Barzilai N, Haines JL, Sano M, Pericak-Vance M, Buxbaum JD. Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer disease. Neurobiology of Aging. 33: 416-417.e3. PMID 20381196 DOI: 10.1016/J.Neurobiolaging.2010.03.003  0.447
2012 Pericak-Vance M, Zuchner S, Kohli M, John-Williams K, Naj A, Rajbhandary R, Whitehead PL, Hamilton-Nelson K, Carney R, Wright C, Crocco E, Gwirtzman H, Lang R, Beecham G, Martin E, et al. Large repeat expansions in the C9ORF72 gene contribute to a spectrum of neurodegenerative disorders including Alzheimer's disease in Caucasians, but not African-Americans Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.277  0.45
2012 Haines J, Naj A, Kohli M, Hamilton-Nelson K, Rajbhandary R, Whitehead PL, Carney R, Crocco E, Wright C, Beecham G, Martin E, Gilbert J, Zuchner S, Pericak-Vance M, Levin B. O5-03-01: Deep resequencing of 9 confirmed late-onset Alzheimer's disease (LOAD) loci identifies multiple genomic regions with potentially functional variants Alzheimer's & Dementia. 8: P734-P735. DOI: 10.1016/J.Jalz.2012.05.1981  0.486
2012 Zuchner S, Kohli M, Naj A, Hamilton K, Rajbhandary R, Plitnik T, John-Williams K, Whitehead PL, Gilbert J, Martin E, Beecham G, Haines J, Pericak-Vance M. Exome sequencing of extended late-onset Alzheimer's disease families identifies a variant in the TTC3 gene Alzheimers & Dementia. 8: 679. DOI: 10.1016/J.Jalz.2012.05.1839  0.515
2012 Kohli M, John-Williams K, Bademci G, Plitnik T, Whitehead PL, Rajbhandary R, Hamilton-Nelson K, Naj A, Wang L, Carney R, Martin E, Beecham G, Vance J, Small G, Gilbert J, et al. Identification of C9ORF72 repeat-expansions in Alzheimer's sample collections Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1823  0.383
2012 Beecham G, Montine T, Rajbhandary R, Hamilton-Nelson K, Naj A, Martin E, Mayeux R, Haines J, Farrer L, Schellenberg G, Pericak-Vance M. P4-102: APP associated with late-onset Alzheimer's disease in an autopsy-confirmed dataset Alzheimer's & Dementia. 8: P668-P668. DOI: 10.1016/J.Jalz.2012.05.1805  0.534
2012 Naj A, Park Y, Rajbhandary R, Hamilton-Nelson K, Beecham G, Martin E, Mayeux R, Haines J, Farrer L, Schellenberg G, Pericak-Vance M. Genome-wide association analyses of onset age in late-onset Alzheimer's disease (LOAD) demonstrate no strong effect outside of the apolipoprotein region Alzheimers & Dementia. 8: 554. DOI: 10.1016/J.Jalz.2012.05.1785  0.341
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.388
2011 Züchner S, Dallman J, Wen R, Beecham G, Naj A, Farooq A, Kohli MA, Whitehead PL, Hulme W, Konidari I, Edwards YJ, Cai G, Peter I, Seo D, Buxbaum JD, et al. Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa. American Journal of Human Genetics. 88: 201-6. PMID 21295283 DOI: 10.1016/J.Ajhg.2011.01.001  0.361
2011 Sherva R, Baldwin CT, Inzelberg R, Vardarajan B, Cupples LA, Lunetta K, Bowirrat A, Naj A, Pericak-Vance M, Friedland RP, Farrer LA. Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data. Journal of Alzheimer's Disease : Jad. 23: 349-59. PMID 21098978 DOI: 10.3233/Jad-2010-100714  0.521
2011 Wang L, Valladares O, Lin C, Buros J, Naj A, Farrer L, Pericak-Vance M, Schellenberg G. The ADGC genome browser Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.553  0.311
2011 Naj A, Jun G, Buros J, Gallins P, Farrer L, Haines J, Pericak-Vance M, Schellenberg G. Genome-Wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1 Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.530  0.507
2011 Martin E, Naj A, Park YS, Gallins P, Hamilton K, Rajbhandary R, Haines J, Pericak-Vance M. Genome-Wide Association Analysis Identifies Novel Loci Associated with the Onset Age Among Cases with Late-Onset Alzheimer’s Disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.526  0.476
2010 Naj AC, Beecham GW, Martin ER, Gallins PJ, Powell EH, Konidari I, Whitehead PL, Cai G, Haroutunian V, Scott WK, Vance JM, Slifer MA, Gwirtsman HE, Gilbert JR, Haines JL, et al. Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. Plos Genetics. 6: e1001130. PMID 20885792 DOI: 10.1371/Journal.Pgen.1001130  0.446
2010 Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, et al. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Archives of Neurology. 67: 1473-84. PMID 20697030 DOI: 10.1001/Archneurol.2010.201  0.451
2010 Beecham GW, Naj AC, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA. PCDH11X variation is not associated with late-onset Alzheimer disease susceptibility. Psychiatric Genetics. 20: 321-4. PMID 20523261 DOI: 10.1097/Ypg.0B013E32833B635D  0.429
2010 Cattaert T, Urrea V, Naj AC, De Lobel L, De Wit V, Fu M, Mahachie John JM, Shen H, Calle ML, Ritchie MD, Edwards TL, Van Steen K. FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals. Plos One. 5: e10304. PMID 20421984 DOI: 10.1371/Journal.Pone.0010304  0.3
2010 Kohli MA, Griswold A, Naj AC, Beecham G, Haines JL, Gilbert J, Pericak-Vance MA. Comprehensive variant discovery in the Late-Onset Alzheimer Disease susceptibility gene Clusterin using next generation sequencing technology Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.610  0.482
2010 Beecham GW, Schnetz-Boutaud N, Bartlett J, Naj A, Gilbert J, Martin ER, Buxbaum J, Haines JL, Pericak-Vance MA. Copy number polymorphism at chromosome 19 locus associated with late-onset Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.349  0.441
2009 Naj AC, Beecham GW, Slifer MA, Martin ER, Gallins PJ, Konidari I, Whitehead PL, Cai G, Kajiwara Y, Haroutunian V, Gwirtsman HE, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA. Genome-wide association study validates associations in APOE, VDR, SORL1, WWC1, and ELAVL4 and identifies novel candidate genes for late-onset Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.519  0.551
2009 Beecham GW, Naj AC, Cai G, Kajiwara Y, Haroutunian V, Konidari I, Gallins P, Whitehead P, Gilbert JR, Slifer MA, Gwirstman H, Martin ER, Buxbaum J, Haines JL, Pericak-Vance MA. GRB-associated binding protein 2 (GAB2) interacts with APOE to alter risk of late-onset Alzheimer's disease Alzheimers & Dementia. 5: 111. DOI: 10.1016/J.Jalz.2009.05.348  0.453
2009 Slifer MA, Naj A, Beecham G, Martin E, Konidari I, Whitehead P, Gallins P, Cai G, Kajiwara Y, Haroutunian V, Vance J, Haines J, Buxbaum J, Pericak-Vance M. ELAVL4 locus confirmed in depression of Alzheimer's disease Alzheimers & Dementia. 5: 468. DOI: 10.1016/J.Jalz.2009.04.793  0.408
2006 Song Q, Cole JW, O'Connell JR, Stine OC, Gallagher M, Giles WH, Mitchell BD, Wozniak MA, Stern BJ, Sorkin JD, McArdle PF, Naj AC, Xu Q, Gibbons GH, Kittner SJ. Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study. Human Molecular Genetics. 15: 2468-78. PMID 16835261 DOI: 10.1093/Hmg/Ddl169  0.349
2006 Gangadharan P, Leung YY, Valladares O, Chou Y, Kuzma AB, Cantwell LB, Qu L, Lin H, Zhao Y, Malamon JS, Naj AC, Salerno WJ, Schellenberg GD, Wang L. P4-044: THE GCAD CLOUD-BASED WORKFLOW FOR PROCESSING WHOLE EXOME AND WHOLE GENOME DATA FROM THE ALZHEIMER'S DISEASE SEQUENCING PROJECT Alzheimer's & Dementia. 14: P1450-P1450. DOI: 10.1016/J.Jalz.2018.06.2446  0.471
2006 Vogel B, Kuzma AB, Valladares O, Greenfest-Allen E, Gangadharan P, Zhao Y, Zhong C, Katanic Z, Qu L, Lin H, Leung YY, Naj AC, Stoeckert CJ, Schellenberg G, Wang L. P1-157: NIA GENETICS OF ALZHEIMER'S DISEASE DATA STORAGE SITE (NIAGADS): UPDATE 2018 Alzheimer's & Dementia. 14: P337-P337. DOI: 10.1016/J.Jalz.2018.06.161  0.483
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