Year |
Citation |
Score |
2020 |
Riehl TE, Alvarado D, Ee X, Ciorba MA, Stenson WF. Hyaluronic acid promotes Lgr5 stem cell proliferation and crypt fission through TLR4 and PGE transactivation of EGFR. American Journal of Physiology. Gastrointestinal and Liver Physiology. 319: G63-G73. PMID 32538139 DOI: 10.1152/Ajpgi.00242.2019 |
0.348 |
|
2020 |
Seiler KM, Bajinting A, Alvarado DM, Traore MA, Binkley MM, Goo WH, Lanik WE, Ou J, Ismail U, Iticovici M, King CR, VanDussen KL, Swietlicki EA, Gazit V, Guo J, et al. Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model. Scientific Reports. 10: 3842. PMID 32123209 DOI: 10.1038/S41598-020-60672-5 |
0.319 |
|
2019 |
Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA. Epithelial IDO1 Modulates AHR and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota. Gastroenterology. PMID 31325428 DOI: 10.1053/J.Gastro.2019.07.013 |
0.381 |
|
2019 |
Bishnupuri KS, Alvarado DM, Khouri AN, Shabsovich M, Chen B, Dieckgraefe BK, Ciorba MA. IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis. Cancer Research. PMID 30679179 DOI: 10.1158/0008-5472.Can-18-0668 |
0.385 |
|
2019 |
Alvarado DM, Santhanam S, Iticovici M, VanDussen K, Shaikh N, Chen B, Lim C, Guillemin G, Tarr PI, Ciorba MA. 11 EPITHELIAL IDO1 MODULATES AHR AND NOTCH SIGNALING TO ENHANCE SECRETORY CELL DIFFERENTIATION AND ALTERS MUCUS-ASSOCIATED MICROBIOTA Gastroenterology. 156: S84. DOI: 10.1053/J.Gastro.2019.01.195 |
0.372 |
|
2019 |
Alvarado DM, Chen B, Iticovici M, VanDussen KL, Shaikh N, Lim CK, Guillemin G, Tarr PI, Ciorba MA. 422 – Epithelial Ido1 Modulates Ahr and Notch Signaling to Enhance Secretory Cell Differentiation, Augment Mucus Barrier, and Alter Microbiota Gastroenterology. 156: S-82. DOI: 10.1016/S0016-5085(19)36995-1 |
0.36 |
|
2018 |
Riehl TE, Alvarado D, Ee X, Zuckerman A, Foster L, Kapoor V, Thotala D, Ciorba MA, Stenson WF. GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells. Gut. PMID 29934438 DOI: 10.1136/Gutjnl-2018-316226 |
0.309 |
|
2018 |
Alvarado D, Santhanam S, Iticovici M, Chen B, Ciorba M. P059 Indoleamine 2,3-Dioxygenase 1 Expression Promotes Epithelial Secretory Cell Differentiation Via Aryl Hydrocarbon Receptor Gastroenterology. 154. DOI: 10.1053/J.Gastro.2017.11.097 |
0.381 |
|
2017 |
Santhanam S, Alvarado D, Khouri A, Dieckgraefe B, Bishnupuri K, Ciorba M. PD-236 Defining the Signaling Pathways and Functional Role for Kynurenine Metabolites in the Normal and Neoplastic Colon Epithelium Inflammatory Bowel Diseases. 23. DOI: 10.1097/01.Mib.0000512751.45611.59 |
0.321 |
|
2016 |
Alvarado DM, McCall K, Hecht JT, Dobbs MB, Gurnett CA. Deletions of 5' HOXC genes are associated with lower extremity malformations, including clubfoot and vertical talus. Journal of Medical Genetics. 53: 250-5. PMID 26729820 DOI: 10.1136/Jmedgenet-2015-103505 |
0.362 |
|
2016 |
Santhanam S, Alvarado DM, Ciorba MA. Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer. Translational Research : the Journal of Laboratory and Clinical Medicine. 167: 67-79. PMID 26297050 DOI: 10.1016/J.Trsl.2015.07.003 |
0.304 |
|
2016 |
Alvarado DM, Santhanam S, Markov A, Shabsovich M, Ciorba MA. 248 IDO1 Expression Enhances Epithelial Differentiation Along the Secretory Cell Pathway and Alters Gut Microbiota Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30322-5 |
0.442 |
|
2015 |
Haller G, Alvarado D, McCall K, Yang P, Cruchaga C, Harms M, Goate A, Willing M, Morcuende JA, Baschal E, Miller NH, Wise C, Dobbs MB, Gurnett CA. A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis. Human Molecular Genetics. PMID 26566670 DOI: 10.1093/Hmg/Ddv463 |
0.365 |
|
2015 |
Cushing K, Alvarado DM, Ciorba MA. Butyrate and Mucosal Inflammation: New Scientific Evidence Supports Clinical Observation. Clinical and Translational Gastroenterology. 6: e108. PMID 26312412 DOI: 10.1038/Ctg.2015.34 |
0.345 |
|
2015 |
Baschal EE, Wethey CI, Swindle K, Baschal RM, Gowan K, Tang NL, Alvarado DM, Haller GE, Dobbs MB, Taylor MR, Gurnett CA, Jones KL, Miller NH. Exome sequencing identifies a rare HSPG2 variant associated with familial idiopathic scoliosis. G3 (Bethesda, Md.). 5: 167-74. PMID 25504735 DOI: 10.1534/G3.114.015669 |
0.379 |
|
2015 |
Santhanam S, Khouri A, Shabsovich M, Alvarado D, Dieckgraefe BK, Bishnupuri KS, Ciorba MA. Sa1977 Kynurenine Metabolic Pathway As a Rational Target for Colorectal Cancer: Defining Its Role in β-Catenin Signaling Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)31250-6 |
0.401 |
|
2014 |
Buchan JG, Alvarado DM, Haller GE, Cruchaga C, Harms MB, Zhang T, Willing MC, Grange DK, Braverman AC, Miller NH, Morcuende JA, Tang NL, Lam TP, Ng BK, Cheng JC, et al. Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis. Human Molecular Genetics. 23: 5271-82. PMID 24833718 DOI: 10.1093/Hmg/Ddu224 |
0.327 |
|
2014 |
Alvarado DM, Yang P, Druley TE, Lovett M, Gurnett CA. Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection. Nucleic Acids Research. 42: e82. PMID 24682816 DOI: 10.1093/Nar/Gku218 |
0.497 |
|
2013 |
Alvarado DM, Buchan JG, Frick SL, Herzenberg JE, Dobbs MB, Gurnett CA. Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb development. European Journal of Human Genetics : Ejhg. 21: 373-80. PMID 22892537 DOI: 10.1038/Ejhg.2012.177 |
0.412 |
|
2011 |
Benitez BA, Alvarado D, Cai Y, Mayo K, Chakraverty S, Norton J, Morris JC, Sands MS, Goate A, Cruchaga C. Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis. Plos One. 6: e26741. PMID 22073189 DOI: 10.1371/Journal.Pone.0026741 |
0.329 |
|
2011 |
Alvarado DM, McCall K, Aferol H, Silva MJ, Garbow JR, Spees WM, Patel T, Siegel M, Dobbs MB, Gurnett CA. Pitx1 haploinsufficiency causes clubfoot in humans and a clubfoot-like phenotype in mice. Human Molecular Genetics. 20: 3943-52. PMID 21775501 DOI: 10.1093/Hmg/Ddr313 |
0.318 |
|
2011 |
Alvarado DM, Buchan JG, Gurnett CA, Dobbs MB. Exome sequencing identifies an MYH3 mutation in a family with distal arthrogryposis type 1. The Journal of Bone and Joint Surgery. American Volume. 93: 1045-50. PMID 21531865 DOI: 10.2106/Jbjs.J.02004 |
0.355 |
|
2011 |
Alvarado DM, Hawkins RD, Bashiardes S, Veile RA, Ku YC, Powder KE, Spriggs MK, Speck JD, Warchol ME, Lovett M. An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4535-43. PMID 21430154 DOI: 10.1523/Jneurosci.5456-10.2011 |
0.673 |
|
2009 |
Alvarado DM, Veile R, Speck J, Warchol M, Lovett M. Downstream targets of GATA3 in the vestibular sensory organs of the inner ear. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 3093-102. PMID 19924793 DOI: 10.1002/Dvdy.22149 |
0.645 |
|
2007 |
Hawkins RD, Bashiardes S, Powder KE, Sajan SA, Bhonagiri V, Alvarado DM, Speck J, Warchol ME, Lovett M. Large scale gene expression profiles of regenerating inner ear sensory epithelia. Plos One. 2: e525. PMID 17565378 DOI: 10.1371/Journal.Pone.0000525 |
0.618 |
|
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