☰

Stephen M. Testa - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
RNA Catalysts
Website:
http://www.chem.uky.edu/research/testa/
Tree Info Similar researchers PubMed Report error

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Testa SM, Selegue JP, French A, Criswell B. Permanganate Oxidation of DNA Nucleotides: An Introductory Redox Laboratory Framed as a Murder Mystery Journal of Chemical Education. 95: 1840-1847. DOI: 10.1021/Acs.Jchemed.8B00079  0.635
2016 Thomas EM, Testa SM. The colorimetric determination of selectively cleaved adenosines and guanosines in DNA oligomers using bicinchoninic acid and copper. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 27807667 DOI: 10.1007/S00775-016-1405-4  0.437
2012 Dotson PP, Hart J, Noe C, Testa SM. Ribozyme-mediated trans insertion-splicing into target RNAs. Methods in Molecular Biology (Clifton, N.J.). 848: 385-94. PMID 22315082 DOI: 10.1007/978-1-61779-545-9_24  0.782
2010 Hart JL, Harris ZM, Testa SM. Analyzing and predicting the thermodynamic effects of the metabolite trehalose on nucleic acids. Biopolymers. 93: 1085-92. PMID 20665686 DOI: 10.1002/Bip.21525  0.697
2008 Dotson PP, Johnson AK, Testa SM. Tetrahymena thermophila and Candida albicans group I intron-derived ribozymes can catalyze the trans-excision-splicing reaction. Nucleic Acids Research. 36: 5281-9. PMID 18684993 DOI: 10.1093/Nar/Gkn507  0.782
2008 Dotson PP, Frommeyer KN, Testa SM. Ribozyme mediated trans insertion-splicing of modified oligonucleotides into RNA. Archives of Biochemistry and Biophysics. 478: 81-4. PMID 18671935 DOI: 10.1016/J.Abb.2008.07.010  0.829
2008 Dotson PP, Sinha J, Testa SM. Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction. The Febs Journal. 275: 3110-22. PMID 18479464 DOI: 10.1111/J.1742-4658.2008.06464.X  0.82
2008 Dotson PP, Sinha J, Testa SM. A Pneumocystis carinii group I intron-derived ribozyme utilizes an endogenous guanosine as the first reaction step nucleophile in the trans excision-splicing reaction. Biochemistry. 47: 4780-7. PMID 18363339 DOI: 10.1021/Bi7020525  0.825
2005 Johnson AK, Sinha J, Testa SM. Trans insertion-splicing: ribozyme-catalyzed insertion of targeted sequences into RNAs. Biochemistry. 44: 10702-10. PMID 16060679 DOI: 10.1021/Bi0504815  0.825
2005 Alexander RC, Baum DA, Testa SM. 5' transcript replacement in vitro catalyzed by a group I intron-derived ribozyme. Biochemistry. 44: 7796-804. PMID 15909994 DOI: 10.1021/Bi047284A  0.724
2005 Baum DA, Testa SM. In vivo excision of a single targeted nucleotide from an mRNA by a trans excision-splicing ribozyme. Rna (New York, N.Y.). 11: 897-905. PMID 15872183 DOI: 10.1261/Rna.2050505  0.701
2005 Baum DA, Sinha J, Testa SM. Molecular recognition in a trans excision-splicing ribozyme: non-Watson-Crick base pairs at the 5' splice site and omegaG at the 3' splice site can play a role in determining the binding register of reaction substrates. Biochemistry. 44: 1067-77. PMID 15654763 DOI: 10.1021/Bi0482304  0.738
2004 Bell MA, Sinha J, Johnson AK, Testa SM. Enhancing the second step of the trans excision-splicing reaction of a group I ribozyme by exploiting P9.0 and P10 for intermolecular recognition. Biochemistry. 43: 4323-31. PMID 15065876 DOI: 10.1021/Bi035874N  0.744
2003 Alexander RC, Johnson AK, Thorpe JA, Gevedon T, Testa SM. Canonical nucleosides can be utilized by T4 DNA ligase as universal template bases at ligation junctions. Nucleic Acids Research. 31: 3208-16. PMID 12799448 DOI: 10.1093/Nar/Gkg415  0.696
2003 Johnson AK, Baum DA, Tye J, Bell MA, Testa SM. Molecular recognition properties of IGS-mediated reactions catalyzed by a Pneumocystis carinii group I intron. Nucleic Acids Research. 31: 1921-34. PMID 12655009 DOI: 10.1093/Nar/Gkg280  0.793
2003 Alexander RC, Johnson AK, Thorpe JA, Gevedon T, Testa SM. Canonical nucleosides can be utilized by T4 DNA ligase as universal template bases at ligation junctions Nucleic Acids Research. 31: 3208-3216. DOI: 10.1093/nar/gkg415  0.647
2002 Bell MA, Johnson AK, Testa SM. Ribozyme-catalyzed excision of targeted sequences from within RNAs. Biochemistry. 41: 15327-33. PMID 12484771 DOI: 10.1021/Bi0267386  0.813
2000 Disney MD, Testa SM, Turner DH. Targeting a Pneumocystis carinii group I intron with methylphosphonate oligonucleotides: backbone charge is not required for binding or reactivity. Biochemistry. 39: 6991-7000. PMID 10841781 DOI: 10.1021/Bi992937M  0.627
1999 Testa SM, Disney MD, Turner DH, Kierzek R. Thermodynamics of RNA-RNA duplexes with 2- or 4-thiouridines: implications for antisense design and targeting a group I intron. Biochemistry. 38: 16655-62. PMID 10600128 DOI: 10.1021/Bi991187D  0.611
1999 Testa SM, Gryaznov SM, Turner DH. In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide. Proceedings of the National Academy of Sciences of the United States of America. 96: 2734-9. PMID 10077580 DOI: 10.1073/Pnas.96.6.2734  0.493
1998 Testa SM, Gryaznov SM, Turner DH. Antisense binding enhanced by tertiary interactions: binding of phosphorothioate and N3'-->P5' phosphoramidate hexanucleotides to the catalytic core of a group I ribozyme from the mammalian pathogen Pneumocystis carinii. Biochemistry. 37: 9379-85. PMID 9649319 DOI: 10.1021/Bi980092T  0.419
1997 Testa SM, Haidaris CG, Gigliotti F, Turner DH. A Pneumocystis carinii group I intron ribozyme that does not require 2' OH groups on its 5' exon mimic for binding to the catalytic core. Biochemistry. 36: 15303-14. PMID 9398259 DOI: 10.1021/Bi9713097  0.472
1997 Profenno LA, Kierzek R, Testa SM, Turner DH. Guanosine binds to the Tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging pro-Sp phosphoryl oxygen at the cleavage site are required for productive docking. Biochemistry. 36: 12477-85. PMID 9376352 DOI: 10.1021/Bi9708895  0.354
1993 Testa SM, Gilham PT. Analysis of oligonucleotide structure using hyperchromism measurements at long wavelengths. Nucleic Acids Research. 21: 3907-8. PMID 8367315 DOI: 10.1093/Nar/21.16.3907  0.559
Show low-probability matches.