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Jinming Gao, Ph.D. - Publications

Affiliations: 
1998-2005 Department of Biomedical Engineering Case Western Reserve University, Cleveland Heights, OH, United States 
 2005- Department of Pharmacology University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Pharmacology, Biomedical Engineering, Polymer Science
Website:
http://www4.utsouthwestern.edu/gaolab/
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Year Citation  Score
2020 Wilhelm J, Wang Z, Sumer BD, Gao J. Exploiting Nanoscale Cooperativity for precision medicine. Advanced Drug Delivery Reviews. PMID 32882321 DOI: 10.1016/J.Addr.2020.08.012  0.386
2020 Voskuil FJ, Steinkamp PJ, Zhao T, van der Vegt B, Koller M, Doff JJ, Jayalakshmi Y, Hartung JP, Gao J, Sumer BD, Witjes MJH, van Dam GM. Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery. Nature Communications. 11: 3257. PMID 32591522 DOI: 10.1038/S41467-020-16814-4  0.374
2020 Huang T, Feng Q, Wang Z, Li W, Sun Z, Wilhelm J, Huang G, Vo T, Sumer BD, Gao J. Tumor-Targeted Inhibition of Monocarboxylate Transporter 1 Improves T-Cell Immunotherapy of Solid Tumors. Advanced Healthcare Materials. e2000549. PMID 32431046 DOI: 10.1002/Adhm.202000549  0.366
2020 Bennett ZT, Feng Q, Bishop JA, Huang G, Sumer BD, Gao J. Detection of Lymph Node Metastases by Ultra-pH-Sensitive Polymeric Nanoparticles. Theranostics. 10: 3340-3350. PMID 32194872 DOI: 10.7150/Thno.41239  0.336
2020 Miller J, Luo M, Wang H, Wang Z, Ding X, Campbell A, Almazan J, Chen Z, Gao J, Zhao T. P857 ONM-500 – a novel STING-activating therapeutic nanovaccine platform for cancer immunotherapy Journal For Immunotherapy of Cancer. 8. DOI: 10.1136/Lba2019.11  0.34
2020 Steinkamp P, Voskuil F, Vegt Bvd, Doff JJ, Zhao T, Hartung J, Jayalakshmi Y, Sumer B, Gao J, Witjes M, Dam Gv. Metabolic Acidosis in Cancer: A New Strategy Using a Ph Activated Imaging Agent for Fluorescence-Guided Surgery in Humans Ejso. 46. DOI: 10.1016/J.Ejso.2019.11.433  0.307
2019 Huang G, Zhao T, Wang C, Nham K, Xiong Y, Gao X, Wang Y, Hao G, Ge WP, Sun X, Sumer BD, Gao J. PET imaging of occult tumours by temporal integration of tumour-acidosis signals from pH-sensitive Cu-labelled polymers. Nature Biomedical Engineering. PMID 31235828 DOI: 10.1038/S41551-019-0416-1  0.336
2019 Feng Q, Wilhelm J, Gao J. Transistor-like Ultra-pH-Sensitive Polymeric Nanoparticles. Accounts of Chemical Research. PMID 31067025 DOI: 10.1021/Acs.Accounts.9B00080  0.316
2019 Kong C, Li Y, Liu Z, Ye J, Wang Z, Zhang L, Kong W, Liu H, Liu C, Pang H, Hu Z, Gao J, Qian F. Targeting the Oncogene KRAS-Mutant Pancreatic Cancer by Synergistic Blocking of Lysosomal Acidification and Rapid Drug Release. Acs Nano. PMID 30912923 DOI: 10.1021/Acsnano.8B08246  0.379
2019 Luo M, Liu Z, Zhang X, Han C, Samandi LZ, Dong C, Sumer BD, Lea J, Fu YX, Gao J. Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30844475 DOI: 10.1016/J.Jconrel.2019.02.036  0.343
2019 Voskuil FJ, Steinkamp PJ, Koller M, Vegt Bvd, Doff JJ, Zhao T, Hartung JP, Jayalakshmi Y, Sumer BD, Gao J, Witjes MJH, Dam GMV. Image-guided surgery for tumor agnostic detection of solid tumors using the pH-activated micellar imaging agent ONM-100. Journal of Clinical Oncology. 37: 3068-3068. DOI: 10.1200/Jco.2019.37.15_Suppl.3068  0.346
2019 Steinkamp P, Voskuil F, Koller M, Vegt Bvd, Doff J, Zhao T, Hartung J, Jayalakshmi Y, Sumer B, Gao J, Witjes M, Dam Gv. Image guided surgery for tumor detection in breast cancer using the PH activated micellar tracer ONM-100: The SHINE study Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-14-29  0.356
2019 Steinkamp PJ, Voskuil FJ, Koller M, Vegt Bvd, Doff JJ, Zhao T, Hartung JP, Jayalakshmi Y, Sumer BD, Gao J, Witjes MJ, Dam GMv. Abstract CT018: Image guided surgery for tumor agnostic detection of solid tumors using the pH activated micellar imaging agent ONM-100: The Shine study Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct018  0.354
2017 Wang C, Wang Z, Zhao T, Li Y, Huang G, Sumer BD, Gao J. Optical molecular imaging for tumor detection and image-guided surgery. Biomaterials. 157: 62-75. PMID 29245052 DOI: 10.1016/J.Biomaterials.2017.12.002  0.318
2017 Luo M, Wang H, Wang Z, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka MR, Lea J, Frankel AE, Fu YX, Chen ZJ, ... Gao J, et al. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology. PMID 28436963 DOI: 10.1038/Nnano.2017.52  0.308
2016 Zhao T, Huang G, Li Y, Yang S, Ramezani S, Lin Z, Wang Y, Ma X, Zeng Z, Luo M, de Boer E, Xie XJ, Thibodeaux J, Brekken RA, Sun X, ... ... Gao J, et al. A Transistor-like pH Nanoprobe for Tumour Detection and Image-guided Surgery. Nature Biomedical Engineering. 1. PMID 28966871 DOI: 10.1038/S41551-016-0006  0.323
2016 Zhou Y, Dong Y, Huang G, Wang Y, Huang X, Zhang F, Boothman DA, Gao J, Liang W. Lysosome-oriented, dual-stage pH-responsive polymeric micelles for β-Lapachone delivery. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 4: 7429-7440. PMID 28580145 DOI: 10.1039/C6Tb02049F  0.33
2016 Wang Z, Luo M, Mao C, Wei Q, Zhao T, Li Y, Huang G, Gao J. A Redox-Activatable Fluorescent Sensor for the High-Throughput Quantification of Cytosolic Delivery of Macromolecules. Angewandte Chemie (International Ed. in English). PMID 27981718 DOI: 10.1002/Anie.201610302  0.333
2016 Li Y, Zhao T, Wang C, Lin Z, Huang G, Sumer BD, Gao J. Molecular basis of cooperativity in pH-triggered supramolecular self-assembly. Nature Communications. 7: 13214. PMID 27786266 DOI: 10.1038/Ncomms13214  0.306
2016 Wang C, Zhao T, Li Y, Huang G, White MA, Gao J. Investigation of Endosome and Lysosome Biology by Ultra pH-Sensitive Nanoprobes. Advanced Drug Delivery Reviews. PMID 27612550 DOI: 10.1016/J.Addr.2016.08.014  0.337
2015 Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA. Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone. Scientific Reports. 5: 17066. PMID 26602448 DOI: 10.1038/Srep17066  0.355
2015 Ma X, Moore ZR, Huang G, Huang X, Boothman DA, Gao J. Nanotechnology-enabled delivery of NQO1 bioactivatable drugs. Journal of Drug Targeting. 23: 672-80. PMID 26453163 DOI: 10.3109/1061186X.2015.1073296  0.336
2015 Wang C, Wang Y, Li Y, Bodemann B, Zhao T, Ma X, Huang G, Hu Z, DeBerardinis RJ, White MA, Gao J. A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nature Communications. 6: 8524. PMID 26437053 DOI: 10.1038/Ncomms9524  0.329
2015 Zhang L, Chen Z, Yang K, Liu C, Gao J, Qian F. β-Lapachone and Paclitaxel Combination Micelles with Improved Drug Encapsulation and Therapeutic Synergy as Novel Nanotherapeutics for NQO1-Targeted Cancer Therapy. Molecular Pharmaceutics. PMID 26415823 DOI: 10.1021/Acs.Molpharmaceut.5B00448  0.393
2015 Ma X, Huang X, Moore Z, Huang G, Kilgore JA, Wang Y, Hammer S, Williams NS, Boothman DA, Gao J. Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 200: 201-11. PMID 25542645 DOI: 10.1016/J.Jconrel.2014.12.027  0.323
2014 Ma X, Wang Y, Zhao T, Li Y, Su LC, Wang Z, Huang G, Sumer BD, Gao J. Ultra-pH-sensitive nanoprobe library with broad pH tunability and fluorescence emissions. Journal of the American Chemical Society. 136: 11085-92. PMID 25020134 DOI: 10.1021/Ja5053158  0.328
2014 Zhou H, Stafford JH, Hallac RR, Zhang L, Huang G, Mason RP, Gao J, Thorpe PE, Zhao D. Phosphatidylserine-targeted molecular imaging of tumor vasculature by magnetic resonance imaging. Journal of Biomedical Nanotechnology. 10: 846-55. PMID 24734537 DOI: 10.1166/Jbn.2014.1851  0.331
2014 Morales J, Li L, Fattah FJ, Dong Y, Bey EA, Patel M, Gao J, Boothman DA. Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. Critical Reviews in Eukaryotic Gene Expression. 24: 15-28. PMID 24579667 DOI: 10.1615/Critreveukaryotgeneexpr.2013006875  0.317
2014 Sun JY, Shen J, Thibodeaux J, Huang G, Wang Y, Gao J, Low PS, Dimitrov DS, Sumer BD. In vivo optical imaging of folate receptor-β in head and neck squamous cell carcinoma. The Laryngoscope. 124: E312-9. PMID 24448885 DOI: 10.1002/Lary.24606  0.325
2014 Wang Y, Zhou K, Huang G, Hensley C, Huang X, Ma X, Zhao T, Sumer BD, DeBerardinis RJ, Gao J. A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals. Nature Materials. 13: 204-12. PMID 24317187 DOI: 10.1038/Nmat3819  0.34
2014 Huang X, Moore Z, Luo X, Chakrabarti G, Ilcheva M, Brekken R, Burma S, Gao J, Deberardinis R, Bornmann W, Hergenrother P, Boothman DA. Abstract 787: DNA repair and metabolism inhibitors are tumor-selective when combined with NQO1 bioactivatable drugs for therapy against pancreatic and nonsmall cell lung cancers Cancer Research. 74: 787-787. DOI: 10.1158/1538-7445.Am2014-787  0.35
2013 Togao O, Kessinger CW, Huang G, Soesbe TC, Sagiyama K, Dimitrov I, Sherry AD, Gao J, Takahashi M. Characterization of lung cancer by amide proton transfer (APT) imaging: an in-vivo study in an orthotopic mouse model. Plos One. 8: e77019. PMID 24143199 DOI: 10.1371/Journal.Pone.0077019  0.317
2013 Bey EA, Reinicke KE, Srougi MC, Varnes M, Anderson VE, Pink JJ, Li LS, Patel M, Cao L, Moore Z, Rommel A, Boatman M, Lewis C, Euhus DM, Bornmann WG, ... ... Gao J, et al. Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers Molecular Cancer Therapeutics. 12: 2110-2120. PMID 23883585 DOI: 10.1158/1535-7163.Mct-12-0962  0.313
2013 Zhang S, Zhou K, Huang G, Takahashi M, Sherry AD, Gao J. A novel class of polymeric pH-responsive MRI CEST agents. Chemical Communications (Cambridge, England). 49: 6418-20. PMID 23752496 DOI: 10.1039/C3Cc42452A  0.316
2013 Huang G, Chen H, Dong Y, Luo X, Yu H, Moore Z, Bey EA, Boothman DA, Gao J. Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy. Theranostics. 3: 116-26. PMID 23423156 DOI: 10.7150/Thno.5411  0.35
2013 Li LS, Reddy S, Gao J, Boothman DA, Sumer B, Yordy JS. Abstract 589: NQO1-dependent anticancer action with combination β-lapachone and ionizing radiation in the head and neck cancer. Cancer Research. 73: 589-589. DOI: 10.1158/1538-7445.Am2013-589  0.326
2012 Huang X, Dong Y, Bey EA, Kilgore JA, Bair JS, Li LS, Patel M, Parkinson EI, Wang Y, Williams NS, Gao J, Hergenrother PJ, Boothman DA. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis. Cancer Research. 72: 3038-47. PMID 22532167 DOI: 10.1158/0008-5472.Can-11-3135  0.333
2012 Zhou K, Liu H, Zhang S, Huang X, Wang Y, Huang G, Sumer BD, Gao J. Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli. Journal of the American Chemical Society. 134: 7803-11. PMID 22524413 DOI: 10.1021/Ja300176W  0.309
2012 Zheng N, Dai W, Du W, Zhang H, Lei L, Zhang H, Wang X, Wang J, Zhang X, Gao J, Zhang Q. A novel lanreotide-encoded micelle system targets paclitaxel to the tumors with overexpression of somatostatin receptors. Molecular Pharmaceutics. 9: 1175-88. PMID 22435704 DOI: 10.1021/Mp200464X  0.38
2011 Yu H, Zou Y, Wang Y, Huang X, Huang G, Sumer BD, Boothman DA, Gao J. Overcoming endosomal barrier by amphotericin B-loaded dual pH-responsive PDMA-b-PDPA micelleplexes for siRNA delivery. Acs Nano. 5: 9246-55. PMID 22011045 DOI: 10.1021/Nn203503H  0.335
2011 Ding H, Yu H, Dong Y, Tian R, Huang G, Boothman DA, Sumer BD, Gao J. Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia. Journal of Controlled Release : Official Journal of the Controlled Release Society. 156: 276-80. PMID 21888934 DOI: 10.1016/J.Jconrel.2011.08.019  0.332
2011 Ding H, Mora R, Gao J, Sumer BD. Characterization and optimization of mTHPP nanoparticles for photodynamic therapy of head and neck cancer. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 145: 612-7. PMID 21727244 DOI: 10.1177/0194599811412449  0.323
2011 Kessinger CW, Togao O, Khemtong C, Huang G, Takahashi M, Gao J. Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI. Theranostics. 1: 263-73. PMID 21562632 DOI: 10.7150/Thno/V01P0263  0.349
2011 Zhou K, Wang Y, Huang X, Luby-Phelps K, Sumer BD, Gao J. Tunable, ultrasensitive pH-responsive nanoparticles targeting specific endocytic organelles in living cells. Angewandte Chemie (International Ed. in English). 50: 6109-14. PMID 21495146 DOI: 10.1002/Anie.201100884  0.375
2011 Khemtong C, Togao O, Ren J, Kessinger CW, Takahashi M, Sherry AD, Gao J. Off-resonance saturation MRI of superparamagnetic nanoprobes: theoretical models and experimental validations. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 209: 53-60. PMID 21277813 DOI: 10.1016/J.Jmr.2010.12.013  0.324
2011 Tao L, Hu W, Liu Y, Huang G, Sumer BD, Gao J. Shape-specific polymeric nanomedicine: emerging opportunities and challenges. Experimental Biology and Medicine (Maywood, N.J.). 236: 20-9. PMID 21239732 DOI: 10.1258/Ebm.2010.010243  0.301
2011 Ding H, Sumer BD, Kessinger CW, Dong Y, Huang G, Boothman DA, Gao J. Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX. Journal of Controlled Release : Official Journal of the Controlled Release Society. 151: 271-7. PMID 21232562 DOI: 10.1016/J.Jconrel.2011.01.004  0.338
2011 Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J, Xie XJ, Brekken RA, Barnett CC, Bornmann WG, Gao J, Boothman DA. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy Clinical Cancer Research. 17: 275-285. PMID 21224367 DOI: 10.1158/1078-0432.Ccr-10-1983  0.306
2011 Cao N, Cheng D, Zou S, Ai H, Gao J, Shuai X. The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells. Biomaterials. 32: 2222-32. PMID 21186059 DOI: 10.1016/J.Biomaterials.2010.11.061  0.399
2011 Chen H, Khemtong C, Yang X, Chang X, Gao J. Nanonization strategies for poorly water-soluble drugs. Drug Discovery Today. 16: 354-60. PMID 20206289 DOI: 10.1016/J.Drudis.2010.02.009  0.3
2011 Cheng D, Hong G, Wang W, Yuan R, Ai H, Shen J, Liang B, Gao J, Shuai X. Nonclustered magnetite nanoparticle encapsulated biodegradable polymeric micelles with enhanced properties for in vivo tumor imaging Journal of Materials Chemistry. 21: 4796-4804. DOI: 10.1039/C0Jm03783D  0.365
2010 Kessinger CW, Khemtong C, Togao O, Takahashi M, Sumer BD, Gao J. In vivo angiogenesis imaging of solid tumors by alpha(v)beta(3)-targeted, dual-modality micellar nanoprobes. Experimental Biology and Medicine (Maywood, N.J.). 235: 957-65. PMID 20660096 DOI: 10.1258/Ebm.2010.010096  0.374
2010 Cohen EM, Ding H, Kessinger CW, Khemtong C, Gao J, Sumer BD. Polymeric micelle nanoparticles for photodynamic treatment of head and neck cancer cells. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 143: 109-15. PMID 20620628 DOI: 10.1016/J.Otohns.2010.03.032  0.346
2010 Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, Chen H, Kessinger CW, Carnevale KA, Bornmann WG, Boothman DA, Gao J. β-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy Cancer Research. 70: 3896-3904. PMID 20460521 DOI: 10.1158/0008-5472.Can-09-3995  0.351
2010 Tao L, Zhao XM, Gao J, Hu W. Lithographically defined uniform worm-shaped polymeric nanoparticles. Nanotechnology. 21: 95301. PMID 20110578 DOI: 10.1088/0957-4484/21/9/095301  0.305
2010 Guthi JS, Yang SG, Huang G, Li S, Khemtong C, Kessinger CW, Peyton M, Minna JD, Brown KC, Gao J. MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells. Molecular Pharmaceutics. 7: 32-40. PMID 19708690 DOI: 10.1021/Mp9001393  0.377
2009 Huang G, Zhang C, Li S, Khemtong C, Yang SG, Tian R, Minna JD, Brown KC, Gao J. A Novel Strategy for Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Lung Cancer Imaging. Journal of Materials Chemistry. 19: 6367-6372. PMID 20505790 DOI: 10.1039/B902358E  0.335
2009 Khemtong C, Kessinger CW, Gao J. Polymeric nanomedicine for cancer MR imaging and drug delivery. Chemical Communications (Cambridge, England). 3497-510. PMID 19521593 DOI: 10.1039/B821865J  0.373
2009 Buyukserin F, Aryal M, Gao J, Hu W. Fabrication of polymeric nanorods using bilayer nanoimprint lithography. Small (Weinheim An Der Bergstrasse, Germany). 5: 1632-6. PMID 19347857 DOI: 10.1002/Smll.200801822  0.314
2009 Khemtong C, Kessinger CW, Ren J, Bey EA, Yang SG, Guthi JS, Boothman DA, Sherry AD, Gao J. In vivo off-resonance saturation magnetic resonance imaging of alphavbeta3-targeted superparamagnetic nanoparticles. Cancer Research. 69: 1651-8. PMID 19190328 DOI: 10.1158/0008-5472.Can-08-3231  0.347
2009 Chen G, Chen W, Wu Z, Yuan R, Li H, Gao J, Shuai X. MRI-visible polymeric vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression. Biomaterials. 30: 1962-70. PMID 19162315 DOI: 10.1016/J.Biomaterials.2008.12.043  0.316
2009 Dong Y, Chin SF, Blanco E, Bey EA, Kabbani W, Xie XJ, Bornmann WG, Boothman DA, Gao J. Intratumoral delivery of β-lapachone via polymer implants for prostate cancer therapy Clinical Cancer Research. 15: 131-139. PMID 19118040 DOI: 10.1158/1078-0432.Ccr-08-1691  0.342
2009 Blanco E, Kessinger CW, Sumer BD, Gao J. Multifunctional micellar nanomedicine for cancer therapy. Experimental Biology and Medicine (Maywood, N.J.). 234: 123-31. PMID 19064945 DOI: 10.3181/0808-Mr-250  0.404
2008 Weinberg BD, Patel RB, Wu H, Blanco E, Barnett CC, Exner AA, Saidel GM, Gao J. Model simulation and experimental validation of intratumoral chemotherapy using multiple polymer implants. Medical & Biological Engineering & Computing. 46: 1039-49. PMID 18523817 DOI: 10.1007/S11517-008-0354-7  0.352
2008 Yang X, Deng W, Fu L, Blanco E, Gao J, Quan D, Shuai X. Folate-functionalized polymeric micelles for tumor targeted delivery of a potent multidrug-resistance modulator FG020326. Journal of Biomedical Materials Research. Part A. 86: 48-60. PMID 17941015 DOI: 10.1002/Jbm.A.31537  0.365
2008 Weinberg BD, Blanco E, Gao J. Polymer implants for intratumoral drug delivery and cancer therapy. Journal of Pharmaceutical Sciences. 97: 1681-702. PMID 17847077 DOI: 10.1002/Jps.21038  0.364
2008 Yang X, Chen Y, Yuan R, Chen G, Blanco E, Gao J, Shuai X. Folate-encoded and Fe3O4-loaded polymeric micelles for dual targeting of cancer cells Polymer. 49: 3477-3485. DOI: 10.1016/J.Polymer.2008.06.005  0.385
2007 Weinberg BD, Patel RB, Exner AA, Saidel GM, Gao J. Modeling doxorubicin transport to improve intratumoral drug delivery to RF ablated tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 124: 11-9. PMID 17900740 DOI: 10.1016/J.Jconrel.2007.08.023  0.321
2007 Sutton D, Wang S, Nasongkla N, Gao J, Dormidontova EE. Doxorubicin and beta-lapachone release and interaction with micellar core materials: experiment and modeling. Experimental Biology and Medicine (Maywood, N.J.). 232: 1090-9. PMID 17720955 DOI: 10.3181/0702-Rm-31  0.338
2007 Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA. An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone Proceedings of the National Academy of Sciences of the United States of America. 104: 11832-11837. PMID 17609380 DOI: 10.1073/Pnas.0702176104  0.309
2007 Blanco E, Bey EA, Dong Y, Weinberg BD, Sutton DM, Boothman DA, Gao J. Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 122: 365-74. PMID 17574288 DOI: 10.1016/J.Jconrel.2007.04.014  0.366
2007 Sutton D, Nasongkla N, Blanco E, Gao J. Functionalized micellar systems for cancer targeted drug delivery. Pharmaceutical Research. 24: 1029-46. PMID 17385025 DOI: 10.1007/S11095-006-9223-Y  0.396
2007 Wang F, Saidel GM, Gao J. A mechanistic model of controlled drug release from polymer millirods: effects of excipients and complex binding. Journal of Controlled Release : Official Journal of the Controlled Release Society. 119: 111-20. PMID 17379347 DOI: 10.1016/J.Jconrel.2007.01.019  0.317
2007 Weinberg BD, Blanco E, Lempka SF, Anderson JM, Exner AA, Gao J. Combined radiofrequency ablation and doxorubicin-eluting polymer implants for liver cancer treatment. Journal of Biomedical Materials Research. Part A. 81: 205-13. PMID 17120205 DOI: 10.1002/Jbm.A.30926  0.35
2007 Weinberg BD, Ai H, Blanco E, Anderson JM, Gao J. Antitumor efficacy and local distribution of doxorubicin via intratumoral delivery from polymer millirods. Journal of Biomedical Materials Research. Part A. 81: 161-70. PMID 17120197 DOI: 10.1002/Jbm.A.30914  0.337
2006 Sutton D, Kim S, Shuai X, Leskov K, Marques JT, Williams BR, Boothman DA, Gao J. Efficient suppression of secretory clusterin levels by polymer-siRNA nanocomplexes enhances ionizing radiation lethality in human MCF-7 breast cancer cells in vitro. International Journal of Nanomedicine. 1: 155-62. PMID 17722531 DOI: 10.2147/Nano.2006.1.2.155  0.349
2006 Nasongkla N, Bey E, Ren J, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao J. Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano Letters. 6: 2427-30. PMID 17090068 DOI: 10.1021/Nl061412U  0.366
2006 Blanco E, Weinberg BD, Stowe NT, Anderson JM, Gao J. Local release of dexamethasone from polymer millirods effectively prevents fibrosis after radiofrequency ablation. Journal of Biomedical Materials Research. Part A. 76: 174-82. PMID 16265662 DOI: 10.1002/Jbm.A.30516  0.325
2006 Sutton D, Durand R, Shuai X, Gao J. zPoly(D, L-lactide-co-glycolide)/poly(ethylenimine) blend matrix system for pH sensitive drug delivery Journal of Applied Polymer Science. 100: 89-96. DOI: 10.1002/App.22636  0.34
2005 Ai H, Pink JJ, Shuai X, Boothman DA, Gao J. Interactions between self-assembled polyelectrolyte shells and tumor cells. Journal of Biomedical Materials Research. Part A. 73: 303-12. PMID 15806565 DOI: 10.1002/Jbm.A.30289  0.331
2005 Ough M, Lewis A, Bey EA, Gao J, Ritchie JM, Bornmann W, Boothman DA, Oberley LW, Cullen JJ. Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1. Cancer Biology & Therapy. 4: 95-102. PMID 15662131 DOI: 10.4161/Cbt.4.1.1382  0.334
2005 Ai H, Flask C, Weinberg B, Shuai X, Pagel MD, Farrell D, Duerk J, Gao J. Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes Advanced Materials. 17: 1949-1952. DOI: 10.1002/Adma.200401904  0.323
2004 Shuai X, Ai H, Nasongkla N, Kim S, Gao J. Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 98: 415-26. PMID 15312997 DOI: 10.1016/J.Jconrel.2004.06.003  0.373
2003 Szymanski-Exner A, Gallacher A, Stowe NT, Weinberg B, Haaga JR, Gao J. Local carboplatin delivery and tissue distribution in livers after radiofrequency ablation. Journal of Biomedical Materials Research. Part A. 67: 510-6. PMID 14566792 DOI: 10.1002/Jbm.A.10038  0.319
2002 Qian F, Saidel GM, Sutton DM, Exner A, Gao J. Combined modeling and experimental approach for the development of dual-release polymer millirods. Journal of Controlled Release : Official Journal of the Controlled Release Society. 83: 427-35. PMID 12387950 DOI: 10.1016/S0168-3659(02)00217-1  0.344
2002 Szymanski-Exner A, Stowe NT, Lazebnik RS, Salem K, Wilson DL, Haaga JR, Gao J. Noninvasive monitoring of local drug release in a rabbit radiofrequency (RF) ablation model using X-ray computed tomography. Journal of Controlled Release : Official Journal of the Controlled Release Society. 83: 415-25. PMID 12387949 DOI: 10.1016/S0168-3659(02)00216-X  0.305
2002 Gao J, Qian F, Szymanski-Exner A, Stowe N, Haaga J. In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers. Journal of Biomedical Materials Research. 62: 308-14. PMID 12209952 DOI: 10.1002/Jbm.10292  0.35
2002 Qian F, Nasongkla N, Gao J. Membrane-encased polymer millirods for sustained release of 5-fluorouracil. Journal of Biomedical Materials Research. 61: 203-11. PMID 12007200 DOI: 10.1002/Jbm.10156  0.3
2001 Qian F, Szymanski A, Gao J. Fabrication and characterization of controlled release poly(D,L-lactide-co-glycolide) millirods. Journal of Biomedical Materials Research. 55: 512-22. PMID 11288079 DOI: 10.1002/1097-4636(20010615)55:4<512::Aid-Jbm1044>3.0.Co;2-N  0.327
1998 Gao J, Niklason L, Zhao XM, Langer R. Surface Modification of Polyanhydride Microspheres Journal of Pharmaceutical Sciences. 87: 246-248. PMID 9519161 DOI: 10.1021/Js970284U  0.335
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