Debra L. Laskin - Publications

Affiliations: 
Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Immunology, Molecular Biology

252 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bellomo A, Herbert J, Kudlak MJ, Laskin JD, Gow AJ, Laskin DL. Identification of early events in nitrogen mustard pulmonary toxicity that are independent of infiltrating inflammatory cells using precision cut lung slices. Toxicology and Applied Pharmacology. 116941. PMID 38677601 DOI: 10.1016/j.taap.2024.116941  0.378
2024 Malaviya R, Meshanni J, Sunil VR, Venosa A, Guo C, Abramova EV, Vayas KN, Jiang C, Cervelli JA, Gow AJ, Laskin JD, Laskin DL. Role of macrophage bioenergetics in N-acetylcysteine-mediated mitigation of lung injury and oxidative stress induced by nitrogen mustard. Toxicology and Applied Pharmacology. 116908. PMID 38513841 DOI: 10.1016/j.taap.2024.116908  0.802
2023 Malaviya R, Laskin JD, Businaro R, Laskin DL. Targeting Tumor Necrosis Factor-alpha to Mitigate Lung Injury induced by Mustard Vesicants and Radiation. Disaster Medicine and Public Health Preparedness. 1-25. PMID 37848400 DOI: 10.1017/dmp.2023.178  0.407
2023 Cody Smith L, Gow AJ, Abramova E, Vayas K, Guo C, Noto J, Lyman J, Rodriquez J, Gelfand-Titiyevskiy B, Malcolm C, Laskin JD, Laskin DL. Role of PPARγ in dyslipidemia and altered pulmonary functioning in mice following ozone exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 37202362 DOI: 10.1093/toxsci/kfad048  0.374
2023 Meshanni JA, Lee JM, Vayas KN, Sun R, Jiang C, Guo GL, Gow AJ, Laskin JD, Laskin DL. . The Journal of Pharmacology and Experimental Therapeutics. PMID 37188530 DOI: 10.1124/jpet.123.001557  0.438
2023 Cary CM, Seymore TN, Singh D, Vayas KN, Goedken MJ, Adams S, Polunas M, Sunil VR, Laskin DL, Demokritou P, Stapleton PA. Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats. Particle and Fibre Toxicology. 20: 16. PMID 37088832 DOI: 10.1186/s12989-023-00525-x  0.688
2023 Gowdy KM, Laskin DL. Resolution of inflammation in xenobiotic-induced mucosal injury and chronic disease. Toxicology and Applied Pharmacology. 116455. PMID 36907382 DOI: 10.1016/j.taap.2023.116455  0.308
2023 Malaviya R, Gardner CR, Rancourt RC, Smith LC, Abramova EV, Vayas KN, Gow AJ, Laskin JD, Laskin DL. Lung injury and oxidative stress induced by inhaled chlorine in mice is associated with proinflammatory activation of macrophages and altered bioenergetics. Toxicology and Applied Pharmacology. 461: 116388. PMID 36690086 DOI: 10.1016/j.taap.2023.116388  0.507
2022 Radbel J, Meshanni JA, Gardner CR, Le-Hoang O, Cervelli J, Laskin JD, Gow AJ, Laskin DL. Novel method to assess resident alveolar macrophage efferocytosis of apoptotic neutrophils by flow cytometry. Toxicology and Applied Pharmacology. 460: 116359. PMID 36565939 DOI: 10.1016/j.taap.2022.116359  0.384
2022 Taylor S, Murray A, Francis M, Abramova E, Guo C, Laskin DL, Gow AJ. Regulation of macrophage activation by S-Nitrosothiols following ozone-induced lung injury. Toxicology and Applied Pharmacology. 116281. PMID 36244437 DOI: 10.1016/j.taap.2022.116281  0.482
2022 Sunil VR, Vayas KN, Radbel J, Abramova E, Gow A, Laskin JD, Laskin DL. Impaired energy metabolism and altered functional activity of alveolar type II epithelial cells following exposure of rats to nitrogen mustard. Toxicology and Applied Pharmacology. 116257. PMID 36174670 DOI: 10.1016/j.taap.2022.116257  0.742
2022 Murray A, Banota T, Guo GL, Smith LC, Meshanni JA, Lee J, Kong B, Abramova EV, Goedken M, Gow AJ, Laskin JD, Laskin DL. Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure. Toxicology and Applied Pharmacology. 116208. PMID 35998709 DOI: 10.1016/j.taap.2022.116208  0.486
2022 Carnino JM, Lee H, Smith LC, Sunil VR, Rancourt R, Vayas K, Cervelli J, Kwok ZH, Ni K, Laskin JD, Jin Y, Laskin DL. Microvesicle-derived miRNAs Regulate Proinflammatory Macrophage Activation in the Lung following Ozone Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 35201360 DOI: 10.1093/toxsci/kfac025  0.669
2021 Malaviya R, Bellomo A, Abramova E, Croutch CR, Roseman J, Tuttle R, Peters E, Casillas RP, Sunil VR, Laskin JD, Laskin DL. Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody. Toxicology and Applied Pharmacology. 428: 115677. PMID 34390737 DOI: 10.1016/j.taap.2021.115677  0.788
2021 Venosa A, Gow JG, Taylor S, Golden T, Murray A, Abramova E, Malaviya R, Laskin DL, Gow AJ. Myeloid cell dynamics in bleomycin-induced pulmonary injury in mice; effects of anti-TNFα antibody. Toxicology and Applied Pharmacology. 115470. PMID 33647319 DOI: 10.1016/j.taap.2021.115470  0.405
2020 Murray A, Gow AJ, Venosa A, Andres J, Malaviya R, Adler D, Yurkow E, Laskin JD, Laskin DL. Assessment of mustard vesicant lung injury and anti-TNF-α efficacy in rodents using live-animal imaging. Annals of the New York Academy of Sciences. PMID 33165947 DOI: 10.1111/nyas.14525  0.335
2020 Malaviya R, Abramova EV, Rancourt RC, Sunil VR, Napierala M, Weinstock D, Croutch CR, Roseman J, Tuttle R, Peters E, Casillas RP, Laskin JD, Laskin DL. Progressive Lung Injury, Inflammation and Fibrosis in Rats following Inhalation of Sulfur Mustard. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 33002157 DOI: 10.1093/toxsci/kfaa150  0.757
2020 Francis M, Guo G, Kong B, Abramova EV, Cervelli JA, Gow AJ, Laskin JD, Laskin DL. Regulation of Lung Macrophage Activation and Oxidative Stress Following Ozone Exposure by Farnesoid X Receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32984886 DOI: 10.1093/Toxsci/Kfaa111  0.578
2020 Mishin V, Heck DE, Laskin DL, Laskin JD. The Amplex Red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxide in the presence of NAD(P)H. Free Radical Research. 1-32. PMID 32912004 DOI: 10.1080/10715762.2020.1821883  0.323
2020 Smith LC, Venosa A, Gow AJ, Laskin JD, Laskin DL. Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard. Annals of the New York Academy of Sciences. PMID 32767459 DOI: 10.1111/Nyas.14444  0.532
2020 Radbel J, Laskin DL, Laskin JD, Kipen HM. Disease-modifying treatment of chemical threat agent-induced acute lung injury. Annals of the New York Academy of Sciences. PMID 32726497 DOI: 10.1111/Nyas.14438  0.416
2020 Businaro R, Maggi E, Armeli F, Murray A, Laskin DL. Nutraceuticals as potential therapeutics for vesicant-induced pulmonary fibrosis. Annals of the New York Academy of Sciences. PMID 32725637 DOI: 10.1111/Nyas.14442  0.5
2020 Wahler G, Heck DE, Heindel ND, Laskin DL, Laskin JD, Joseph LB. Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard. Experimental and Molecular Pathology. 104410. PMID 32113906 DOI: 10.1016/J.Yexmp.2020.104410  0.379
2020 Lee J, Sunil VR, Vayas K, Abramova E, Cervelli J, Laskin JD, Laskin DL. Abrogation of Ozone‐induced Oxidative Stress, Inflammation, and Aberrant Pulmonary Mechanics by Valproic Acid The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04256  0.727
2020 Malcolm C, Smith LC, Gow AJ, Laskin D. PPARγ Regulates the Inflammatory Response to Ozone‐Induced Lung Injury in Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02421  0.486
2019 Andres J, Smith LC, Murray A, Jin Y, Businaro R, Laskin JD, Laskin DL. Role of extracellular vesicles in cell-cell communication and inflammation following exposure to pulmonary toxicants. Cytokine & Growth Factor Reviews. PMID 31901309 DOI: 10.1016/J.Cytogfr.2019.12.001  0.491
2019 Malaviya R, Laskin JD, Laskin DL. Long-term Respiratory Effects of Mustard Vesicants. Toxicology Letters. PMID 31698045 DOI: 10.1016/J.Toxlet.2019.10.026  0.381
2019 Sunil VR, Vayas KN, Abramova EV, Rancourt R, Cervelli JA, Malaviya R, Goedken M, Venosa A, Gow AJ, Laskin JD, Laskin DL. Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard. Toxicology and Applied Pharmacology. 114798. PMID 31678244 DOI: 10.1016/J.Taap.2019.114798  0.785
2019 Venosa A, Smith LC, Murray A, Banota T, Gow AJ, Laskin JD, Laskin DL. Regulation of Macrophage Foam Cell Formation during Nitrogen Mustard (NM)-Induced Pulmonary Fibrosis by Lung Lipids. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31428777 DOI: 10.1093/Toxsci/Kfz187  0.499
2019 Jan YH, Heck DE, Laskin DL, Laskin JD. The sulfur mustard analog mechlorethamine (bis(2-chloroethyl)methylamine) modulates cell cycle progression via the DNA damage response in human lung epithelial A549 cells. Chemical Research in Toxicology. PMID 30964658 DOI: 10.1021/Acs.Chemrestox.8B00417  0.319
2019 Sunil VR, Radbel J, Hussain S, Vayas KN, Cervelli J, Deen M, Kipen H, Udasin I, Laumbach R, Sunderram J, Laskin JD, Laskin DL. Sarcoid-Like Granulomatous Disease: Pathologic Case Series in World Trade Center Dust Exposed Rescue and Recovery Workers. International Journal of Environmental Research and Public Health. 16. PMID 30845693 DOI: 10.3390/Ijerph16050815  0.737
2019 Businaro R, Corsi M, Asprino R, Di Lorenzo C, Laskin D, Corbo RM, Ricci S, Pinto A. Modulation of Inflammation as a Way of Delaying Alzheimer's Disease Progression: The Diet's Role. Current Alzheimer Research. 15: 363-380. PMID 28847284 DOI: 10.2174/1567205014666170829100100  0.365
2018 Laskin DL, Malaviya R, Laskin JD. Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30590802 DOI: 10.1093/Toxsci/Kfy309  0.49
2018 Sunil VR, Vayas KN, Cervelli JA, Ebramova E, Gow AJ, Goedken M, Laskin JD, Laskin DL. Protective Role of Surfactant Protein-D against Lung Injury and Oxidative Stress induced by Nitrogen Mustard. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30060251 DOI: 10.1093/Toxsci/Kfy188  0.792
2018 Lee H, Zhang D, Laskin DL, Jin Y. Functional Evidence of Pulmonary Extracellular Vesicles in Infectious and Noninfectious Lung Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29997122 DOI: 10.4049/Jimmunol.1800264  0.531
2018 Villeneuve DL, Landesmann B, Allavena P, Ashley N, Bal-Price A, Corsini E, Halappanavar S, Hussell T, Laskin D, Lawrence T, Nikolic-Paterson D, Pallardy M, Paini A, Pieters R, Roth R, et al. Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 163: 346-352. PMID 29850905 DOI: 10.1093/Toxsci/Kfy047  0.347
2018 Radbel J, Le-Hoang O, Vayas KN, Patel K, Goedken M, Sunil VR, Laskin D, Sunderram J. Effect of World Trade Center Dust Exposure and Chronic Intermittent Hypoxia on Macrophage Matrix Metalloproteinase-12 Expression in Mice. Annals of the American Thoracic Society. 15: S125-S126. PMID 29676627 DOI: 10.1513/Annalsats.201706-509Mg  0.734
2017 Massa CB, Groves AM, Jaggernauth SU, Laskin DL, Gow AJ. Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation. Plos Computational Biology. 13: e1005570. PMID 28837561 DOI: 10.1371/Journal.Pcbi.1005570  0.763
2017 Schumacher JD, Kong B, Pan Y, Zhan L, Sun R, Aa J, Rizzolo D, Richardson JR, Chen A, Goedken M, Aleksunes LM, Laskin DL, Guo GL. The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis. Toxicology and Applied Pharmacology. PMID 28673684 DOI: 10.1016/J.Taap.2017.06.023  0.329
2017 Malaviya R, Laskin JD, Laskin DL. Anti-TNFα Therapy in Inflammatory Lung Diseases bn. Pharmacology & Therapeutics. PMID 28642115 DOI: 10.1016/J.Pharmthera.2017.06.008  0.475
2017 Yang S, Jan YH, Mishin V, Heck DE, Laskin DL, Laskin JD. Diacetyl/L-xylulose reductase mediates chemical redox cycling in lung epithelial cells. Chemical Research in Toxicology. PMID 28595002 DOI: 10.1021/Acs.Chemrestox.7B00052  0.401
2017 Venosa A, Gow JG, Hall L, Malaviya R, Gow AJ, Laskin JD, Laskin DL. Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28184907 DOI: 10.1093/Toxsci/Kfx032  0.497
2016 Francis M, Groves AM, Sun R, Cervelli JA, Choi H, Laskin JD, Laskin DL. CCR2 Regulates Inflammatory Cell Accumulation in the Lung and Tissue Injury following Ozone Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28171673 DOI: 10.1093/toxsci/kfw226  0.773
2016 Sunil VR, Vayas KN, Fang M, Zarbl H, Massa C, Gow AJ, Cervelli JA, Kipen H, Laumbach R, Lioy PJ, Laskin JD, Laskin DL. World Trade Center (WTC) dust exposure in mice is associated with inflammation, oxidative stress and epigenetic changes in the lung. Experimental and Molecular Pathology. PMID 27986442 DOI: 10.1016/J.Yexmp.2016.12.005  0.749
2016 Francis M, Groves A, Sun R, Cervelli JA, Choi H, Laskin JD, Laskin DL. CCR2 Regulates Inflammatory Cell Accumulation in the Lung and Tissue Injury Following Ozone Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27837169 DOI: 10.1093/Toxsci/Kfw226  0.822
2016 Francis M, Sun R, Cervelli JA, Choi H, Mandal M, Abramova EV, Gow AJ, Laskin JD, Laskin DL. Role of Spleen-derived Macrophages in Ozone-Induced Lung Inflammation and Injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27708193 DOI: 10.1093/Toxsci/Kfw192  0.582
2016 Jan YH, Richardson JR, Baker AA, Mishin V, Heck DE, Laskin DL, Laskin JD. Novel approaches to mitigating parathion toxicity: targeting cytochrome P450-mediated metabolism with menadione. Annals of the New York Academy of Sciences. PMID 27441453 DOI: 10.1111/Nyas.13156  0.305
2016 Malaviya R, Sunil VR, Venosa A, Vayas KN, Businaro R, Heck DE, Laskin JD, Laskin DL. Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants. Annals of the New York Academy of Sciences. PMID 27351588 DOI: 10.1111/Nyas.13123  0.758
2016 Weinberger B, Malaviya R, Sunil VR, Venosa A, Heck DE, Laskin JD, Laskin DL. Mustard vesicant-induced lung injury: Advances in therapy. Toxicology and Applied Pharmacology. 305: 1-11. PMID 27212445 DOI: 10.1016/J.Taap.2016.05.014  0.776
2016 Composto GM, Laskin JD, Laskin DL, Gerecke DR, Casillas RP, Heindel ND, Joseph LB, Heck DE. Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug. Experimental and Molecular Pathology. PMID 27189522 DOI: 10.1016/J.Yexmp.2016.05.008  0.38
2016 Mandal M, Gardner CR, Sun R, Choi H, Lad S, Mishin V, Laskin JD, Laskin DL. The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury. Toxicology and Applied Pharmacology. PMID 27163765 DOI: 10.1016/J.Taap.2016.04.019  0.501
2016 Wohlman IM, Composto GM, Heck DE, Heindel ND, Lacey CJ, Guillon CD, Casillas RP, Croutch CR, Gerecke DR, Laskin DL, Joseph LB, Laskin JD. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. Toxicology and Applied Pharmacology. PMID 27125198 DOI: 10.1016/J.Taap.2016.04.014  0.352
2016 Szilagyi JT, Mishin V, Heck DE, Jan YH, Aleksunes LM, Richardson JR, Heindel ND, Laskin DL, Laskin JD. Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26880746 DOI: 10.1093/Toxsci/Kfw031  0.377
2016 Liu Z, Groves A, Golden T, Laskin D, Gow A. Age‐Related Changes in Macrophage Proliferative Capacity in Response to Chronic Inflammation and Inhaled Ozone The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.745.7  0.777
2015 Malaviya R, Sunil VR, Venosa A, Vayas KN, Heck DE, Laskin JD, Laskin DL. Inflammatory mechanisms of pulmonary injury induced by mustards. Toxicology Letters. PMID 26478570 DOI: 10.1016/J.Toxlet.2015.10.011  0.787
2015 Venosa A, Malaviya R, Gow AJ, Hall L, Laskin JD, Laskin DL. Protective Role of Spleen-Derived Macrophages in Lung Inflammation, Injury and Fibrosis Induced by Nitrogen Mustard. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00276.2015. PMID 26475734 DOI: 10.1152/Ajplung.00276.2015  0.495
2015 Udasin RG, Wen X, Bircsak KM, Aleksunes LM, Shakarjian MP, Kong AT, Heck DE, Laskin DL, Laskin JD. Nrf2 regulates the sensitivity of mouse keratinocytes to nitrogen mustard via multidrug resistance-associated protein 1 (Mrp1). Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26454883 DOI: 10.1093/Toxsci/Kfv226  0.382
2015 Jan YH, Heck DE, Casillas RP, Laskin DL, Laskin JD. Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction. Chemical Research in Toxicology. 28: 2091-103. PMID 26451472 DOI: 10.1021/Acs.Chemrestox.5B00194  0.333
2015 Venosa A, Malaviya R, Choi H, Gow AJ, Laskin JD, Laskin DL. Characterization of Distinct Macrophage Subpopulations During Nitrogen Mustard-Induced Injury and Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 26273949 DOI: 10.1165/Rcmb.2015-0120Oc  0.447
2015 Malaviya R, Sunil VR, Venosa A, Verissimo VL, Cervelli JA, Vayas KN, Hall L, Laskin JD, Laskin DL. Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody. Toxicological Sciences : An Official Journal of the Society of Toxicology. 148: 71-88. PMID 26243812 DOI: 10.1093/Toxsci/Kfv161  0.781
2015 Jan YH, Richardson JR, Baker AA, Mishin V, Heck DE, Laskin DL, Laskin JD. Vitamin K3 (menadione) redox cycling inhibits cytochrome P450-mediated metabolism and inhibits parathion intoxication. Toxicology and Applied Pharmacology. 288: 114-20. PMID 26212258 DOI: 10.1016/J.Taap.2015.07.023  0.303
2015 Sunil VR, Francis M, Vayas KN, Cervelli JA, Choi H, Laskin JD, Laskin DL. Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3. Toxicology and Applied Pharmacology. 284: 236-45. PMID 25724551 DOI: 10.1016/J.Taap.2015.02.002  0.807
2015 Malaviya R, Gow AJ, Francis M, Abramova EV, Laskin JD, Laskin DL. Radiation-induced lung injury and inflammation in mice: role of inducible nitric oxide synthase and surfactant protein D. Toxicological Sciences : An Official Journal of the Society of Toxicology. 144: 27-38. PMID 25552309 DOI: 10.1093/Toxsci/Kfu255  0.473
2015 Yang S, Jan YH, Mishin V, Richardson JR, Hossain MM, Heindel ND, Heck DE, Laskin DL, Laskin JD. Sulfa drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase. The Journal of Pharmacology and Experimental Therapeutics. 352: 529-40. PMID 25550200 DOI: 10.1124/Jpet.114.221572  0.312
2015 Laskin DL, Malaviya R, Laskin JD. Pulmonary Macrophages Comparative Biology of the Normal Lung: Second Edition. 629-649. DOI: 10.1016/B978-0-12-404577-4.00032-1  0.387
2014 Chang YC, Wang JD, Hahn RA, Gordon MK, Joseph LB, Heck DE, Heindel ND, Young SC, Sinko PJ, Casillas RP, Laskin JD, Laskin DL, Gerecke DR. Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. Toxicology and Applied Pharmacology. 280: 236-44. PMID 25127551 DOI: 10.1016/J.Taap.2014.07.016  0.393
2014 Mishin V, Heck DE, Laskin DL, Laskin JD. Human recombinant cytochrome P450 enzymes display distinct hydrogen peroxide generating activities during substrate independent NADPH oxidase reactions. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 344-52. PMID 25061110 DOI: 10.1093/Toxsci/Kfu133  0.315
2014 Sunil VR, Vayas KN, Cervelli JA, Malaviya R, Hall L, Massa CB, Gow AJ, Laskin JD, Laskin DL. Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. Experimental and Molecular Pathology. 97: 89-98. PMID 24886962 DOI: 10.1016/J.Yexmp.2014.05.009  0.809
2014 Zheng R, Dragomir AC, Mishin V, Richardson JR, Heck DE, Laskin DL, Laskin JD. Differential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats. Toxicology and Applied Pharmacology. 279: 43-52. PMID 24832492 DOI: 10.1016/J.Taap.2014.04.026  0.811
2014 Joseph LB, Heck DE, Cervelli JA, Composto GM, Babin MC, Casillas RP, Sinko PJ, Gerecke DR, Laskin DL, Laskin JD. Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard. Experimental and Molecular Pathology. 96: 316-27. PMID 24662110 DOI: 10.1016/J.Yexmp.2014.03.002  0.343
2014 Jan YH, Heck DE, Dragomir AC, Gardner CR, Laskin DL, Laskin JD. Acetaminophen reactive intermediates target hepatic thioredoxin reductase Chemical Research in Toxicology. 27: 882-894. PMID 24661219 DOI: 10.1021/Tx5000443  0.788
2014 Massa CB, Scott P, Abramova E, Gardner C, Laskin DL, Gow AJ. Acute chlorine gas exposure produces transient inflammation and a progressive alteration in surfactant composition with accompanying mechanical dysfunction. Toxicology and Applied Pharmacology. 278: 53-64. PMID 24582687 DOI: 10.1016/J.Taap.2014.02.006  0.483
2014 Zheng R, Heck DE, Mishin V, Black AT, Shakarjian MP, Kong AN, Laskin DL, Laskin JD. Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product. Toxicology and Applied Pharmacology. 275: 113-21. PMID 24423726 DOI: 10.1016/J.Taap.2014.01.001  0.442
2014 Malaviya R, Laskin JD, Laskin DL. Oxidative stress-induced autophagy: role in pulmonary toxicity. Toxicology and Applied Pharmacology. 275: 145-51. PMID 24398106 DOI: 10.1016/J.Taap.2013.12.022  0.462
2014 Jan YH, Heck DE, Malaviya R, Casillas RP, Laskin DL, Laskin JD. Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. Chemical Research in Toxicology. 27: 61-75. PMID 24274902 DOI: 10.1021/Tx400329A  0.397
2014 Zheng R, Heck DE, Black AT, Gow A, Laskin DL, Laskin JD. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radical Biology & Medicine. 67: 1-9. PMID 24140437 DOI: 10.1016/J.Freeradbiomed.2013.10.011  0.356
2013 Groves AM, Gow AJ, Massa CB, Hall L, Laskin JD, Laskin DL. Age-related increases in ozone-induced injury and altered pulmonary mechanics in mice with progressive lung inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L555-68. PMID 23997172 DOI: 10.1152/Ajplung.00027.2013  0.793
2013 Zheng R, Po I, Mishin V, Black AT, Heck DE, Laskin DL, Sinko PJ, Gerecke DR, Gordon MK, Laskin JD. The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard. Toxicology and Applied Pharmacology. 272: 345-55. PMID 23845594 DOI: 10.1016/J.Taap.2013.06.025  0.418
2013 Yang S, Jan YH, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD. Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells. The Journal of Biological Chemistry. 288: 19221-37. PMID 23640889 DOI: 10.1074/Jbc.M112.402164  0.415
2013 Sunil VR, Vayas KN, Massa CB, Gow AJ, Laskin JD, Laskin DL. Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulmonary mechanics. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 309-19. PMID 23492811 DOI: 10.1093/Toxsci/Kft071  0.785
2013 Kutscher HL, Gao D, Li S, Massa CB, Cervelli J, Deshmukh M, Joseph LB, Laskin DL, Sinko PJ. Toxicodynamics of rigid polystyrene microparticles on pulmonary gas exchange in mice: implications for microemboli-based drug delivery systems. Toxicology and Applied Pharmacology. 266: 214-23. PMID 23142466 DOI: 10.1016/J.Taap.2012.10.021  0.307
2013 Liu Y, Gardner CR, Laskin JD, Laskin DL. Classical and alternative activation of rat hepatic sinusoidal endothelial cells by inflammatory stimuli. Experimental and Molecular Pathology. 94: 160-7. PMID 23103612 DOI: 10.1016/J.Yexmp.2012.10.015  0.4
2013 Connor AJ, Chen LC, Joseph LB, Laskin JD, Laskin DL. Distinct responses of lung and liver macrophages to acute endotoxemia: role of toll-like receptor 4. Experimental and Molecular Pathology. 94: 216-27. PMID 23000425 DOI: 10.1016/J.Yexmp.2012.09.006  0.824
2012 Dragomir AC, Sun R, Choi H, Laskin JD, Laskin DL. Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication. Journal of Immunology (Baltimore, Md. : 1950). 189: 5934-41. PMID 23175698 DOI: 10.4049/Jimmunol.1201851  0.83
2012 Deshmukh M, Kutscher HL, Gao D, Sunil VR, Malaviya R, Vayas K, Stein S, Laskin JD, Laskin DL, Sinko PJ. Biodistribution and renal clearance of biocompatible lung targeted poly(ethylene glycol) (PEG) nanogel aggregates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 65-73. PMID 23041417 DOI: 10.1016/J.Jconrel.2012.09.011  0.7
2012 Malaviya R, Venosa A, Hall L, Gow AJ, Sinko PJ, Laskin JD, Laskin DL. Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor. Toxicology and Applied Pharmacology. 265: 279-91. PMID 22981630 DOI: 10.1016/J.Taap.2012.08.027  0.531
2012 Groves AM, Gow AJ, Massa CB, Laskin JD, Laskin DL. Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflammation. American Journal of Respiratory Cell and Molecular Biology. 47: 776-83. PMID 22878412 DOI: 10.1165/Rcmb.2011-0433Oc  0.821
2012 Sunil VR, Patel-Vayas K, Shen J, Laskin JD, Laskin DL. Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress. Toxicology and Applied Pharmacology. 263: 195-202. PMID 22727909 DOI: 10.1016/J.Taap.2012.06.009  0.806
2012 Gardner CR, Hankey P, Mishin V, Francis M, Yu S, Laskin JD, Laskin DL. Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase. Toxicology and Applied Pharmacology. 262: 139-48. PMID 22575169 DOI: 10.1016/J.Taap.2012.04.027  0.474
2012 Dragomir AC, Sun R, Mishin V, Hall LB, Laskin JD, Laskin DL. Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production. Toxicological Sciences : An Official Journal of the Society of Toxicology. 127: 609-19. PMID 22461450 DOI: 10.1093/Toxsci/Kfs117  0.836
2012 Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL. Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning. Toxicology and Applied Pharmacology. 261: 22-30. PMID 22446026 DOI: 10.1016/J.Taap.2012.03.004  0.819
2012 Connor AJ, Laskin JD, Laskin DL. Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4. Experimental and Molecular Pathology. 92: 229-35. PMID 22300504 DOI: 10.1016/J.Yexmp.2012.01.004  0.84
2012 Gardner CR, Mishin V, Laskin JD, Laskin DL. Exacerbation of acetaminophen hepatotoxicity by the anthelmentic drug fenbendazole. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 607-12. PMID 22048645 DOI: 10.1093/Toxsci/Kfr301  0.322
2012 Laskin D, Malaviya R, Venosa A, Gow A, Heck D, Laskin J. Role of reactive nitrogen species (RNS) generated via inducible nitric oxide synthase in vesicant-induced lung injury and inflammation Nitric Oxide. 27: S44. DOI: 10.1016/J.Niox.2012.04.157  0.554
2011 Joseph LB, Gerecke DR, Heck DE, Black AT, Sinko PJ, Cervelli JA, Casillas RP, Babin MC, Laskin DL, Laskin JD. Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage. Experimental and Molecular Pathology. 91: 515-27. PMID 21672537 DOI: 10.1016/J.Yexmp.2011.05.010  0.41
2011 Dragomir AC, Laskin JD, Laskin DL. Macrophage activation by factors released from acetaminophen-injured hepatocytes: potential role of HMGB1. Toxicology and Applied Pharmacology. 253: 170-7. PMID 21513726 DOI: 10.1016/J.Taap.2011.04.003  0.822
2011 Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 253: 112-20. PMID 21457723 DOI: 10.1016/J.Taap.2011.03.015  0.309
2011 Black AT, Gordon MK, Heck DE, Gallo MA, Laskin DL, Laskin JD. UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells. Biochemical Pharmacology. 81: 873-80. PMID 21300015 DOI: 10.1016/J.Bcp.2011.01.014  0.494
2011 Kipen HM, Gandhi S, Rich DQ, Ohman-Strickland P, Laumbach R, Fan ZH, Chen L, Laskin DL, Zhang J, Madura K. Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. Environmental Health Perspectives. 119: 658-63. PMID 21163722 DOI: 10.1289/Ehp.1002784  0.35
2011 Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL. Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 250: 245-55. PMID 21070800 DOI: 10.1016/J.Taap.2010.10.027  0.805
2011 Laskin DL, Sunil VR, Gardner CR, Laskin JD. Macrophages and tissue injury: agents of defense or destruction? Annual Review of Pharmacology and Toxicology. 51: 267-88. PMID 20887196 DOI: 10.1146/Annurev.Pharmtox.010909.105812  0.754
2011 Sunil VR, Patel KJ, Shen J, Reimer D, Gow AJ, Laskin JD, Laskin DL. Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard. Toxicology and Applied Pharmacology. 250: 10-8. PMID 20883710 DOI: 10.1016/J.Taap.2010.09.016  0.796
2011 Weinberger B, Laskin JD, Sunil VR, Sinko PJ, Heck DE, Laskin DL. Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity. Pulmonary Pharmacology & Therapeutics. 24: 92-9. PMID 20851203 DOI: 10.1016/J.Pupt.2010.09.004  0.79
2011 Liu Y, Wei L, Laskin DL, Fanburg BL. Role of protein transamidation in serotonin-induced proliferation and migration of pulmonary artery smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 44: 548-55. PMID 20558776 DOI: 10.1165/Rcmb.2010-0078Oc  0.301
2011 Zheng R, Black AT, Heck DE, Laskin DL, Laskin JD. Abstract 2091: Nitrooleic acids induce localization of heat shock protein 70 in PAM212 keratinocyte caveolae Cancer Research. 71: 2091-2091. DOI: 10.1158/1538-7445.Am2011-2091  0.355
2010 Laskin DL, Mainelis G, Turpin BJ, Patel KJ, Sunil VR. Pulmonary effects of inhaled diesel exhaust in young and old mice: a pilot project. Research Report (Health Effects Institute). 3-31. PMID 21381634  0.75
2010 Kutscher HL, Chao P, Deshmukh M, Sundara Rajan S, Singh Y, Hu P, Joseph LB, Stein S, Laskin DL, Sinko PJ. Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats. International Journal of Pharmaceutics. 402: 64-71. PMID 20883756 DOI: 10.1016/J.Ijpharm.2010.09.020  0.34
2010 Black AT, Hayden PJ, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 249: 178-87. PMID 20840853 DOI: 10.1016/J.Taap.2010.09.005  0.378
2010 Laskin JD, Black AT, Jan YH, Sinko PJ, Heindel ND, Sunil V, Heck DE, Laskin DL. Oxidants and antioxidants in sulfur mustard-induced injury. Annals of the New York Academy of Sciences. 1203: 92-100. PMID 20716289 DOI: 10.1111/J.1749-6632.2010.05605.X  0.745
2010 Laskin DL, Sunil VR, Fakhrzadeh L, Groves A, Gow AJ, Laskin JD. Macrophages, reactive nitrogen species, and lung injury. Annals of the New York Academy of Sciences. 1203: 60-5. PMID 20716284 DOI: 10.1111/J.1749-6632.2010.05607.X  0.831
2010 Malaviya R, Sunil VR, Cervelli J, Anderson DR, Holmes WW, Conti ML, Gordon RE, Laskin JD, Laskin DL. Inflammatory effects of inhaled sulfur mustard in rat lung. Toxicology and Applied Pharmacology. 248: 89-99. PMID 20659490 DOI: 10.1016/J.Taap.2010.07.018  0.802
2010 Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD. Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species. Toxicology and Applied Pharmacology. 247: 76-82. PMID 20561902 DOI: 10.1016/J.Taap.2010.05.015  0.414
2010 Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD. Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity. Molecular Cancer Therapeutics. 9: 1852-63. PMID 20501808 DOI: 10.1158/1535-7163.Mct-09-1098  0.341
2010 Vetrano AM, Laskin DL, Archer F, Syed K, Gray JP, Laskin JD, Nwebube N, Weinberger B. Inflammatory effects of phthalates in neonatal neutrophils. Pediatric Research. 68: 134-9. PMID 20453712 DOI: 10.1203/PDR.0b013e3181e5c1f7  0.392
2010 Laskin DL, Chen L, Hankey PA, Laskin JD. Role of STK in mouse liver macrophage and endothelial cell responsiveness during acute endotoxemia. Journal of Leukocyte Biology. 88: 373-82. PMID 20453108 DOI: 10.1189/Jlb.0210113  0.508
2010 Malaviya R, Laskin DL, Malaviya R. Janus kinase-3 dependent inflammatory responses in allergic asthma. International Immunopharmacology. 10: 829-36. PMID 20430118 DOI: 10.1016/J.Intimp.2010.04.014  0.381
2010 Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD. Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology. 245: 352-60. PMID 20382172 DOI: 10.1016/J.Taap.2010.04.001  0.469
2010 Jan YH, Heck DE, Gray JP, Zheng H, Casillas RP, Laskin DL, Laskin JD. Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells. Chemical Research in Toxicology. 23: 1045-53. PMID 20345183 DOI: 10.1021/Tx100040K  0.49
2010 Gardner CR, Gray JP, Joseph LB, Cervelli J, Bremer N, Kim Y, Mishin V, Laskin JD, Laskin DL. Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity. Toxicology and Applied Pharmacology. 245: 36-46. PMID 20100502 DOI: 10.1016/J.Taap.2010.01.008  0.498
2010 Kutscher HL, Chao P, Deshmukh M, Singh Y, Hu P, Joseph LB, Reimer DC, Stein S, Laskin DL, Sinko PJ. Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 143: 31-7. PMID 20043961 DOI: 10.1016/J.Jconrel.2009.12.019  0.387
2010 Chao P, Deshmukh M, Kutscher HL, Gao D, Rajan SS, Hu P, Laskin DL, Stein S, Sinko PJ. Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model. Anti-Cancer Drugs. 21: 65-76. PMID 19966540 DOI: 10.1097/Cad.0B013E328332A322  0.365
2010 Shakarjian MP, Heck DE, Gray JP, Sinko PJ, Gordon MK, Casillas RP, Heindel ND, Gerecke DR, Laskin DL, Laskin JD. Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 5-19. PMID 19833738 DOI: 10.1093/Toxsci/Kfp253  0.336
2009 Sunil VR, Patel KJ, Mainelis G, Turpin BJ, Ridgely S, Laumbach RJ, Kipen HM, Nazarenko Y, Veleeparambil M, Gow AJ, Laskin JD, Laskin DL. Pulmonary effects of inhaled diesel exhaust in aged mice. Toxicology and Applied Pharmacology. 241: 283-93. PMID 19729031 DOI: 10.1016/J.Taap.2009.08.025  0.767
2009 Roberts RA, Laskin DL, Smith CV, Robertson FM, Allen EM, Doorn JA, Slikker W. Nitrative and oxidative stress in toxicology and disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. 112: 4-16. PMID 19656995 DOI: 10.1093/Toxsci/Kfp179  0.419
2009 Laskin DL. Macrophages and inflammatory mediators in chemical toxicity: a battle of forces. Chemical Research in Toxicology. 22: 1376-85. PMID 19645497 DOI: 10.1021/Tx900086V  0.41
2009 Laskin JD, Heck DE, Laskin DL. Nitric Oxide Pathways in Toxic Responses General, Applied and Systems Toxicology. DOI: 10.1002/9780470744307.Gat020  0.454
2008 Black AT, Gray JP, Shakarjian MP, Laskin DL, Heck DE, Laskin JD. Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat. Toxicology and Applied Pharmacology. 231: 384-92. PMID 18620719 DOI: 10.1016/J.Taap.2008.05.014  0.397
2008 Black AT, Gray JP, Shakarjian MP, Mishin V, Laskin DL, Heck DE, Laskin JD. UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes. Toxicology and Applied Pharmacology. 232: 14-24. PMID 18597804 DOI: 10.1016/J.Taap.2008.05.017  0.391
2008 Weinberger B, Quizon C, Vetrano AM, Archer F, Laskin JD, Laskin DL. Mechanisms mediating reduced responsiveness of neonatal neutrophils to lipoxin A4. Pediatric Research. 64: 393-8. PMID 18535486 DOI: 10.1203/Pdr.0B013E318180E4Af  0.353
2008 Chen LC, Laskin JD, Gordon MK, Laskin DL. Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia. Experimental and Molecular Pathology. 84: 145-55. PMID 18222421 DOI: 10.1016/J.Yexmp.2007.11.004  0.468
2008 Fakhrzadeh L, Laskin JD, Laskin DL. Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-alpha following ozone inhalation. Toxicology and Applied Pharmacology. 227: 380-9. PMID 18207479 DOI: 10.1016/J.Taap.2007.11.012  0.844
2008 Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD. Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity. Free Radical Biology & Medicine. 44: 1169-79. PMID 18206659 DOI: 10.1016/J.Freeradbiomed.2007.12.013  0.344
2008 Black AT, Gray JP, Shakarjian MP, Laskin DL, Heck DE, Laskin JD. Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differentiated mouse keratinocytes. Carcinogenesis. 29: 219-25. PMID 17984112 DOI: 10.1093/Carcin/Bgm242  0.407
2007 Chen LC, Gordon RE, Laskin JD, Laskin DL. Role of TLR-4 in liver macrophage and endothelial cell responsiveness during acute endotoxemia. Experimental and Molecular Pathology. 83: 311-26. PMID 17996232 DOI: 10.1016/J.Yexmp.2007.08.015  0.451
2007 Sunil VR, Laumbach RJ, Patel KJ, Turpin BJ, Lim HJ, Kipen HM, Laskin JD, Laskin DL. Pulmonary effects of inhaled limonene ozone reaction products in elderly rats. Toxicology and Applied Pharmacology. 222: 211-20. PMID 17610924 DOI: 10.1016/J.Taap.2007.05.003  0.764
2007 Sunil VR, Patel KJ, Nilsen-Hamilton M, Heck DE, Laskin JD, Laskin DL. Acute endotoxemia is associated with upregulation of lipocalin 24p3/Lcn2 in lung and liver. Experimental and Molecular Pathology. 83: 177-87. PMID 17490638 DOI: 10.1016/J.Yexmp.2007.03.004  0.784
2007 Weinberger B, Vetrano AM, Syed K, Murthy S, Hanna N, Laskin JD, Laskin DL. Influence of labor on neonatal neutrophil apoptosis, and inflammatory activity. Pediatric Research. 61: 572-7. PMID 17413861 DOI: 10.1203/Pdr.0B013E318045Be38  0.448
2007 Gray JP, Heck DE, Mishin V, Smith PJ, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, Laskin JD. Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase. The Journal of Biological Chemistry. 282: 7939-49. PMID 17229725 DOI: 10.1074/Jbc.M611817200  0.441
2006 Dambach DM, Durham SK, Laskin JD, Laskin DL. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicology and Applied Pharmacology. 211: 157-65. PMID 16081117 DOI: 10.1016/J.Taap.2005.06.024  0.731
2005 Laumbach RJ, Fiedler N, Gardner CR, Laskin DL, Fan ZH, Zhang J, Weschler CJ, Lioy PJ, Devlin RB, Ohman-Strickland P, Kelly-McNeil K, Kipen HM. Nasal effects of a mixture of volatile organic compounds and their ozone oxidation products. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 47: 1182-9. PMID 16282880 DOI: 10.1097/01.Jom.0000183338.95778.F0  0.317
2005 Martey CA, Vetrano AM, Whittemore MS, Mariano TM, Heck DE, Laskin DL, Heindel ND, Laskin JD. Inhibition of interferon-gamma signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes. Biochemical Pharmacology. 70: 1726-34. PMID 16259964 DOI: 10.1016/J.Bcp.2005.10.001  0.391
2005 Vetrano AM, Heck DE, Mariano TM, Mishin V, Laskin DL, Laskin JD. Characterization of the oxidase activity in mammalian catalase. The Journal of Biological Chemistry. 280: 35372-81. PMID 16079130 DOI: 10.1074/Jbc.M503991200  0.306
2005 Weinberger B, Hanna N, Laskin JD, Heck DE, Gardner CR, Gerecke DR, Laskin DL. Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils. Mediators of Inflammation. 2005: 31-8. PMID 15770064 DOI: 10.1155/Mi.2005.31  0.339
2005 Hanna N, Vasquez P, Pham P, Heck DE, Laskin JD, Laskin DL, Weinberger B. Mechanisms underlying reduced apoptosis in neonatal neutrophils. Pediatric Research. 57: 56-62. PMID 15557111 DOI: 10.1203/01.Pdr.0000147568.14392.F0  0.4
2004 Hanna N, Graboski S, Laskin DL, Weinberger B. Effects of ibuprofen and hypoxia on neutrophil apoptosis in neonates. Biology of the Neonate. 86: 235-9. PMID 15263833 DOI: 10.1159/000079831  0.358
2004 Hanna N, Bonifacio L, Reddy P, Hanna I, Weinberger B, Murphy S, Laskin D, Sharma S. IFN-gamma-mediated inhibition of COX-2 expression in the placenta from term and preterm labor pregnancies. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 51: 311-8. PMID 15212685 DOI: 10.1111/J.1600-0897.2004.00162.X  0.341
2004 Fakhrzadeh L, Laskin JD, Laskin DL. Ozone-induced production of nitric oxide and TNF-alpha and tissue injury are dependent on NF-kappaB p50. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L279-85. PMID 15064226 DOI: 10.1152/Ajplung.00348.2003  0.837
2004 Fakhrzadeh L, Laskin JD, Gardner CR, Laskin DL. Superoxide dismutase-overexpressing mice are resistant to ozone-induced tissue injury and increases in nitric oxide and tumor necrosis factor-alpha. American Journal of Respiratory Cell and Molecular Biology. 30: 280-7. PMID 12855403 DOI: 10.1165/Rcmb.2003-0044Oc  0.852
2004 Laskin DL, Heck DE, Laskin JD. ROLE OF NITRIC OXIDE IN ACUTE LUNG INJURY Shock. 21: 78. DOI: 10.1097/00024382-200403001-00310  0.46
2003 Laskin DL, Morio L, Hooper K, Li TH, Buckley B, Turpin B. Peroxides and macrophages in the toxicity of fine particulate matter in rats. Research Report (Health Effects Institute). 1-51; discussion 53-. PMID 15035594  0.402
2003 Chiu H, Gardner CR, Dambach DM, Durham SK, Brittingham JA, Laskin JD, Laskin DL. Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice. Toxicology and Applied Pharmacology. 193: 218-27. PMID 14644624 DOI: 10.1016/J.Taap.2003.07.003  0.782
2003 Gardner CR, Laskin JD, Dambach DM, Chiu H, Durham SK, Zhou P, Bruno M, Gerecke DR, Gordon MK, Laskin DL. Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators. Toxicology and Applied Pharmacology. 192: 119-30. PMID 14550746 DOI: 10.1016/S0041-008X(03)00273-4  0.799
2003 Chiu H, Gardner CR, Dambach DM, Brittingham JA, Durham SK, Laskin JD, Laskin DL. Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G959-66. PMID 12842828 DOI: 10.1152/Ajpgi.00219.2003  0.791
2002 Gardner CR, Laskin JD, Dambach DM, Sacco M, Durham SK, Bruno MK, Cohen SD, Gordon MK, Gerecke DR, Zhou P, Laskin DL. Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10. Toxicology and Applied Pharmacology. 184: 27-36. PMID 12392966 DOI: 10.1006/Taap.2002.9474  0.75
2002 Laskin JD, Heck DE, Laskin DL. The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 69: 289-91. PMID 12377976 DOI: 10.1093/Toxsci/69.2.289  0.349
2002 Billack B, Heck DE, Mariano TM, Gardner CR, Sur R, Laskin DL, Laskin JD. Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells. American Journal of Physiology. Cell Physiology. 283: C1267-77. PMID 12225989 DOI: 10.1152/Ajpcell.00609.2001  0.421
2002 Sunil VR, Connor AJ, Zhou P, Gordon MK, Laskin JD, Laskin DL. Activation of adherent vascular neutrophils in the lung during acute endotoxemia. Respiratory Research. 3: 21. PMID 12204102 DOI: 10.1186/Rr171  0.817
2002 Laskin DL, Fakhrzadeh L, Heck DE, Gerecke D, Laskin JD. Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation. Role of NF-kappaB and STAT-1 in ozone-induced nitric oxide production and toxicity. Molecular and Cellular Biochemistry. 234: 91-8. PMID 12162464 DOI: 10.1023/A:1015963217045  0.855
2002 Chiu H, Brittingham JA, Laskin DL. Differential induction of heme oxygenase-1 in macrophages and hepatocytes during acetaminophen-induced hepatotoxicity in the rat: Effects of hemin and biliverdin Toxicology and Applied Pharmacology. 181: 106-115. PMID 12051994 DOI: 10.1006/Taap.2002.9409  0.67
2002 Ahmad N, Chen LC, Gordon MA, Laskin JD, Laskin DL. Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia. Journal of Leukocyte Biology. 71: 1005-11. PMID 12050186 DOI: 10.1189/Jlb.71.6.1005  0.71
2002 Weinberger B, Laskin DL, Heck DE, Laskin JD. Oxygen toxicity in premature infants. Toxicology and Applied Pharmacology. 181: 60-7. PMID 12030843 DOI: 10.1006/Taap.2002.9387  0.31
2002 Dambach DM, Watson LM, Gray KR, Durham SK, Laskin DL. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology (Baltimore, Md.). 35: 1093-103. PMID 11981759 DOI: 10.1053/Jhep.2002.33162  0.758
2002 Fakhrzadeh L, Laskin JD, Laskin DL. Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury. American Journal of Respiratory Cell and Molecular Biology. 26: 413-9. PMID 11919077 DOI: 10.1165/Ajrcmb.26.4.4516  0.864
2002 Sunil VR, Connor AJ, Guo Y, Laskin JD, Laskin DL. Activation of type II alveolar epithelial cells during acute endotoxemia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L872-80. PMID 11880315 DOI: 10.1152/Ajplung.00217.2001  0.817
2002 Sunil VR, Connor AJ, Lavnikova N, Gardner CR, Laskin JD, Laskin DL. Acute endotoxemia prolongs the survival of rat lung neutrophils in response to 12-O-tetradecanoyl-phorbol 13-acetate. Journal of Cellular Physiology. 190: 382-9. PMID 11857454 DOI: 10.1002/Jcp.10074  0.827
2001 Laskin DL, Fakhrzadeh L, Laskin JD. Nitric oxide and peroxynitrite in ozone-induced lung injury. Advances in Experimental Medicine and Biology. 500: 183-90. PMID 11764933 DOI: 10.1007/978-1-4615-0667-6_24  0.863
2001 Morio LA, Hooper KA, Brittingham J, Li TH, Gordon RE, Turpin BJ, Laskin DL. Tissue injury following inhalation of fine particulate matter and hydrogen peroxide is associated with altered production of inflammatory mediators and antioxidants by alveolar macrophages. Toxicology and Applied Pharmacology. 177: 188-99. PMID 11749118 DOI: 10.1006/Taap.2001.9316  0.411
2001 Weinberger B, Laskin DL, Mariano TM, Sunil VR, DeCoste CJ, Heck DE, Gardner CR, Laskin JD. Mechanisms underlying reduced responsiveness of neonatal neutrophils to distinct chemoattractants. Journal of Leukocyte Biology. 70: 969-76. PMID 11739560 DOI: 10.1189/Jlb.70.6.969  0.721
2001 Laskin DL, Weinberger B, Laskin JD. Functional heterogeneity in liver and lung macrophages Journal of Leukocyte Biology. 70: 163-170. PMID 11493607 DOI: 10.1189/Jlb.70.2.163  0.48
2001 Laskin JD, Heck DE, Gardner CR, Laskin DL. Prooxidant and antioxidant functions of nitric oxide in liver toxicity Antioxidants and Redox Signaling. 3: 261-271. PMID 11396480 DOI: 10.1089/152308601300185214  0.45
2001 Billack B, Heck DE, Porterfield DM, Malchow RP, Smith PJ, Gardner CR, Laskin DL, Laskin JD. Minimal amidine structure for inhibition of nitric oxide biosynthesis. Biochemical Pharmacology. 61: 1581-6. PMID 11377388 DOI: 10.1016/S0006-2952(01)00630-X  0.43
2001 Weinberger B, Weiss K, Heck DE, Laskin DL, Laskin JD. Pharmacologic therapy of persistent pulmonary hypertension of the newborn Pharmacology and Therapeutics. 89: 67-79. PMID 11316514 DOI: 10.1016/S0163-7258(00)00104-2  0.36
2001 Bissell DM, Gores GJ, Laskin DL, Hoofnagle JH. Drug-induced liver injury: mechanisms and test systems. Hepatology (Baltimore, Md.). 33: 1009-13. PMID 11283870 DOI: 10.1053/Jhep.2001.23505  0.303
2001 Morio LA, Chiu H, Sprowles KA, Zhou P, Heck DE, Gordon MK, Laskin DL. Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice. Toxicology and Applied Pharmacology. 172: 44-51. PMID 11264022 DOI: 10.1006/Taap.2000.9133  0.659
2001 Laskin DL, Laskin JD. Role of macrophages and inflammatory mediators in chemically induced toxicity Toxicology. 160: 111-118. PMID 11246131 DOI: 10.1016/S0300-483X(00)00437-6  0.519
2001 Weinberger B, Laskin DL, Heck DE, Laskin JD. The toxicology of inhaled nitric oxide Toxicological Sciences. 59: 5-16. PMID 11134540 DOI: 10.1093/Toxsci/59.1.5  0.453
2000 Laskin DL, Heck DE, Punjabi CJ, Laskin JD. Nitric oxide as a mediator of benzene-induced hematosuppression and toxicity Journal of Toxicology and Environmental Health - Part A. 61: 413-417. PMID 11086947 DOI: 10.1080/00984100050166433  0.407
2000 Morio LA, Chiu H, Sprowles KA, Laskin DL. Functional heterogeneity of rat hepatic and alveolar macrophages: effects of chronic ethanol administration. Journal of Leukocyte Biology. 68: 614-20. PMID 11073098 DOI: 10.1189/Jlb.68.5.614  0.681
2000 Hooper KA, Nickolas TL, Yurkow EJ, Kohn J, Laskin DL. Characterization of the inflammatory response to biomaterials using a rodent air pouch model. Journal of Biomedical Materials Research. 50: 365-74. PMID 10737878 DOI: 10.1002/(Sici)1097-4636(20000605)50:3<365::Aid-Jbm10>3.0.Co;2-X  0.309
1999 Weinberger B, Heck DE, Laskin DL, Laskin JD. Nitric oxide in the lungtherapeutic and cellular mechanisms of action Pharmacology and Therapeutics. 84: 401-411. PMID 10665837 DOI: 10.1016/S0163-7258(99)00044-3  0.474
1999 Ahmad N, Gardner CR, Yurkow EJ, Laskin DL. Inhibition of macrophages with gadolinium chloride alters intercellular adhesion molecule-1 expression in the liver during acute endotoxemia in rats. Hepatology (Baltimore, Md.). 29: 728-36. PMID 10051474 DOI: 10.1002/Hep.510290324  0.664
1999 Weinberger B, Fakhrzadeh L, Gardner CR, Heck DE, Laskin JD, Laskin DL. Mechanisms Underlying the Pulmonary Toxicity of Inhaled Nitric Oxide Pediatric Research. 45: 326A-326A. DOI: 10.1203/00006450-199904020-01938  0.8
1998 Prokhorova S, Patel N, Laskin DL. Regulation of alveolar macrophage and type II cell DNA synthesis: effects of ozone inhalation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 275: L1200-L1207. PMID 29586296 DOI: 10.1152/Ajplung.1998.275.6.L1200  0.368
1998 Laskin DL, Heck DE, Laskin JD. Role of inflammatory cytokines and nitric oxide in hepatic and pulmonary toxicity Toxicology Letters. 102: 289-293. PMID 10022268 DOI: 10.1016/S0378-4274(98)00316-6  0.614
1998 Laskin DL, Sunil V, Guo Y, Heck DE, Laskin JD. Increased nitric oxide synthase in the lung after ozone inhalation is associated with activation of NF-κB Environmental Health Perspectives. 106: 1175-1178. PMID 9788894 DOI: 10.1289/Ehp.98106S51175  0.797
1998 Gordon RE, Park E, Laskin D, Schuller-Levis GB. Taurine protects rat bronchioles from acute ozone exposure: a freeze fracture and electron microscopic study. Experimental Lung Research. 24: 659-74. PMID 9779375 DOI: 10.3109/01902149809099586  0.434
1998 Weinberger B, Fakhrzadeh L, Heck DE, Laskin JD, Gardner CR, Laskin DL. Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates. American Journal of Respiratory and Critical Care Medicine. 158: 931-8. PMID 9731028 DOI: 10.1164/Ajrccm.158.3.9708014  0.844
1998 Gardner CR, Heck DE, Yang CS, Thomas PE, Zhang XJ, DeGeorge GL, Laskin JD, Laskin DL. Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat. Hepatology (Baltimore, Md.). 27: 748-54. PMID 9500703 DOI: 10.1002/Hep.510270316  0.464
1998 Weinberger BI, Fakhrzadeh L, Gardner CR, Heck DE, Laskin JD, Laskin DL. Mice Lacking Inducible Nitric Oxide Synthase Exhibit Reduced Responsiveness to the Irritant-Inducing Effects of Inhaled Nitric Oxide † 1772 Pediatric Research. 43: 302-302. DOI: 10.1203/00006450-199804001-01794  0.811
1998 Weinberger BI, Laskin JD, Laskin DL, Heck DE. Nitric Oxide Mediates Fas-induced Apoptosis in RAW 264.7 Cells • 46 Pediatric Research. 43: 10-10. DOI: 10.1203/00006450-199804001-00067  0.485
1998 Laskin J, Gardner C, Heck D, Chiu H, Durham S, Laskin D. Mice lacking inducible nitric oxide synthase are protected from acetaminophen-induced hepato-toxicity Toxicology Letters. 95: 113. DOI: 10.1016/S0378-4274(98)80448-7  0.661
1998 Laskin D, Heck D, Laskin J. Role of inflammatory cytokines in hepatic and pulmonary toxicity Toxicology Letters. 95: 13-14. DOI: 10.1016/S0378-4274(98)80053-2  0.419
1997 Lavnikova N, Burdelya L, Lakhotia A, Patel N, Prokhorova S, Laskin DL. Macrophage and interleukin-1 induced nitric oxide production and cytostasis in hamster tumor cells varying in malignant potential. Journal of Leukocyte Biology. 61: 452-8. PMID 9103232 DOI: 10.1002/Jlb.61.4.452  0.414
1997 Weinberger B, Gardner CR, Fakhrzadeh L, Heck DE, Laskin JD, Laskin DL. INCREASED PEROXYNITRITE PRODUCTION BY ALVEOLAR MACROPHAGES (AM) FOLLOWING INHALATION OF NITRIC OXIDE (NO). • 1621 Pediatric Research. 41: 273-273. DOI: 10.1203/00006450-199704001-01640  0.825
1997 Weinberger B, Gardner CR, Fakhrzadeh L, Laskin JD, Laskin DL, Heck DE. INHIBITION OF NF-κB p-50 NUCLEAR TRANSLOCATION REGULATES APOPTOSIS AND EXPRESSION OF BCL-2 IN MACROPHAGES. ♦ 62 Pediatric Research. 41: 13-13. DOI: 10.1203/00006450-199704001-00083  0.789
1996 Laskin DL, Heck DE, Punjabi CJ, Laskin JD. Role of nitric oxide in hematosuppression and benzene-induced toxicity Environmental Health Perspectives. 104: 1283-1287. PMID 9118907 DOI: 10.1289/Ehp.961041283  0.426
1996 Lavnikova N, Lakhotia A, Patel N, Prokhorova S, Laskin DL. Cytostasis is required for IL-1 induced nitric oxide production in transformed hamster fibroblasts. Journal of Cellular Physiology. 169: 532-7. PMID 8952702 DOI: 10.1002/(Sici)1097-4652(199612)169:3<532::Aid-Jcp13>3.0.Co;2-7  0.357
1996 Lavnikova N, Prokhorova S, Burdelia L, Lakhotia A, Laskin DL. Mechanisms regulating macrophage-induced nitric oxide production by spontaneously transformed hamster fibroblasts. Journal of Leukocyte Biology. 60: 473-9. PMID 8864131 DOI: 10.1002/Jlb.60.4.473  0.424
1996 Laskin DL. Sinusoidal lining cells and hepatotoxicity. Toxicologic Pathology. 24: 112-8. PMID 8839288 DOI: 10.1177/019262339602400115  0.503
1996 Rollo EE, Laskin DL, Denhardt DT. Osteopontin inhibits nitric oxide production and cytotoxicity by activated RAW264.7 macrophages Journal of Leukocyte Biology. 60: 397-404. PMID 8830797 DOI: 10.1002/Jlb.60.3.397  0.451
1996 Laskin JD, Heck DE, Laskin DL. Nitric oxide production in the lung and liver following inhalation of the pulmonary irritant ozone Advances in Experimental Medicine and Biology. 387: 141-146. PMID 8794206 DOI: 10.1007/978-1-4757-9480-9_20  0.424
1996 Pendino KJ, Gardner CR, Shuler RL, Laskin JD, Durham SK, Barton DS, Ohnishi ST, Ohnishi T, Laskin DL. Inhibition of Ozone-induced Nitric Oxide Synthase Expression in the Lung by Endotoxin American Journal of Respiratory Cell and Molecular Biology. 14: 516-525. PMID 8652180 DOI: 10.1165/Ajrcmb.14.6.8652180  0.565
1996 Pendino KJ, Gardner CR, Quinones S, Laskin DL. Stimulation of nitric oxide production in rat lung lavage cells by anti-Mac-1beta antibody: effects of ozone inhalation. American Journal of Respiratory Cell and Molecular Biology. 14: 327-33. PMID 8600936 DOI: 10.1165/Ajrcmb.14.4.8600936  0.505
1996 Schuller-Levis GB, Gordon RE, Park E, Pendino KJ, Laskin DL. Taurine protects rat bronchioles from acute ozone-induced lung inflammation and hyperplasia. Experimental Lung Research. 21: 877-88. PMID 8591791 DOI: 10.3109/01902149509031768  0.436
1996 Weinberger B, Laskin D, Gardner C, Fakhrzadeh L, Heck D. REGULATION OF MACROPHAGE NF-κB ACTIVATION DURING THE CELL CYCLE. • 75 Pediatric Research. 39: 15-15. DOI: 10.1203/00006450-199604001-00094  0.793
1996 Laskin DL, Laskin JD. Macrophages, inflammatory mediators, and lung injury Methods: a Companion to Methods in Enzymology. 10: 61-70. DOI: 10.1006/Meth.1996.0079  0.57
1995 Laskin JD, Rao NR, Punjabi CJ, Laskin DL, Snyder R. Distinct actions of benzene and its metabolites on nitric oxide production by bone marrow leukocytes Journal of Leukocyte Biology. 57: 422-426. PMID 7884313 DOI: 10.1002/Jlb.57.3.422  0.393
1995 Gardner CR, Laskin JD, Laskin DL. Distinct biochemical responses of hepatic macrophages and endothelial cells to platelet-activating factor during endotoxemia Journal of Leukocyte Biology. 57: 269-274. PMID 7852841 DOI: 10.1002/Jlb.57.2.269  0.423
1995 Laskin DL, Pendino KJ. Macrophages and inflammatory mediators in tissue injury. Annual Review of Pharmacology and Toxicology. 35: 655-77. PMID 7598511 DOI: 10.1146/Annurev.Pa.35.040195.003255  0.506
1995 Lavnikova N, Laskin DL. Unique patterns of regulation of nitric oxide production in fibroblasts. Journal of Leukocyte Biology. 58: 451-8. PMID 7561522 DOI: 10.1002/Jlb.58.4.451  0.446
1995 Pendino KJ, Meidhof TM, Heck DE, Laskin JD, Laskin DL. Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production American Journal of Respiratory Cell and Molecular Biology. 13: 125-132. PMID 7542894 DOI: 10.1165/Ajrcmb.13.2.7542894  0.515
1995 Laskin DL, Rodriguez Del Valle M, Heck DE, Hwang Sm, Ohnishi ST, Durham SK, Goller NL, Laskin JD. Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression Hepatology. 22: 223-234. PMID 7541386 DOI: 10.1002/Hep.1840220133  0.468
1995 Shuler RL, Laskin DL, Gardner CR, Feder LS, Laskin JD. Lymphocyte-mediated nitric oxide production by rat endothelial cells Journal of Leukocyte Biology. 57: 116-121. PMID 7530277 DOI: 10.1002/Jlb.57.1.116  0.414
1995 Laskin DL, Gardner CR, Price VF, Jollow DJ. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen Hepatology. 21: 1045-1050. DOI: 10.1002/Hep.1840210424  0.44
1994 Prokhorova S, Lavnikova N, Laskin DL. Functional characterization of interstitial macrophages and subpopulations of alveolar macrophages from rat lung. Journal of Leukocyte Biology. 55: 141-6. PMID 8301209 DOI: 10.1002/Jlb.55.2.141  0.523
1994 Laskin DL, Soltys RA, Berg RA, Riley DJ. Activation of alveolar macrophages by native and synthetic collagen-like polypeptides American Journal of Respiratory Cell and Molecular Biology. 10: 58-64. PMID 8292381 DOI: 10.1165/Ajrcmb.10.1.8292381  0.421
1994 Punjabi CJ, Laskin JD, Hwang SM, MacEachern L, Laskin DL. Enhanced production of nitric oxide by bone marrow cells and increased sensitivity to macrophage colony-stimulating factor (CSF) and granulocyte- macrophage CSF after benzene treatment of mice Blood. 83: 3255-3263. PMID 8193360 DOI: 10.1182/Blood.V83.11.3255.Bloodjournal83113255  0.459
1994 Wizemann TM, Laskin DL. Enhanced phagocytosis, chemotaxis, and production of reactive oxygen intermediates by interstitial lung macrophages following acute endotoxemia. American Journal of Respiratory Cell and Molecular Biology. 11: 358-65. PMID 8086172 DOI: 10.1165/Ajrcmb.11.3.8086172  0.524
1994 Pendino KJ, Shuler RL, Laskin JD, Laskin DL. Enhanced production of interleukin-1, tumor necrosis factor-alpha, and fibronectin by rat lung phagocytes following inhalation of a pulmonary irritant American Journal of Respiratory Cell and Molecular Biology. 11: 279-286. PMID 8086166 DOI: 10.1165/Ajrcmb.11.3.8086166  0.466
1994 Wizemann TM, Laskin DL. Effects of acute endotoxemia on production of cytokines and nitric oxide by pulmonary alveolar and interstitial macrophages. Annals of the New York Academy of Sciences. 730: 336-7. PMID 8080204 DOI: 10.1111/J.1749-6632.1994.Tb44284.X  0.472
1994 Rodriguez-del Valle M, Hwang SM, Heck DE, Laskin JD, Laskin DL. Role of nitric oxide in hepatic injury following acute endotoxemia Annals of the New York Academy of Sciences. 730: 329-331. PMID 8080202 DOI: 10.1111/J.1749-6632.1994.Tb44282.X  0.369
1994 Garcia-Welsh A, Laskin DL, Shuler RL, Laskin JD. Cellular depletion of p56(lck) during thymocyte apoptosis Journal of Leukocyte Biology. 56: 528-532. PMID 7930951 DOI: 10.1002/Jlb.56.4.528  0.325
1994 Laskin DL, Pendino KJ, Punjabi CJ, Rodriguez del Valle M, Laskin JD. Pulmonary and hepatic effects of inhaled ozone in rats Environmental Health Perspectives. 102: 61-64. PMID 7705308 DOI: 10.1289/Ehp.94102S1061  0.582
1994 Wizemann TM, Gardner CR, Laskin JD, Quinones S, Durham SK, Goller NL, Ohnishi ST, Laskin DL. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia. Journal of Leukocyte Biology. 56: 759-68. PMID 7527832 DOI: 10.1002/Jlb.56.6.759  0.533
1994 Laskin DL, Heck DE, Gardner CR, Feder LS, Laskin JD. Distinct patterns of nitric oxide production in hepatic macrophages and endothelial cells following acute exposure of rats to endotoxin Journal of Leukocyte Biology. 56: 751-758. PMID 7527831 DOI: 10.1002/Jlb.56.6.751  0.499
1994 Helyar L, Bundschuh DS, Laskin JD, Laskin DL. Induction of hepatic Ito cell nitric oxide production after acute endotoxemia Hepatology. 20: 1509-1515. PMID 7527004 DOI: 10.1002/Hep.1840200621  0.449
1994 Garcia-Welsh A, Laskin DL, Hwang SM, Denhardt DT, Laskin JD. Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage-inducible nitric oxide synthase Journal of Leukocyte Biology. 56: 488-494. PMID 7523558 DOI: 10.1002/Jlb.56.4.488  0.455
1994 Punjabi CJ, Laskin JD, Pendino KJ, Goller NL, Durham SK, Laskin DL. Production of nitric oxide by rat type II pneumocytes: increased expression of inducible nitric oxide synthase following inhalation of a pulmonary irritant American Journal of Respiratory Cell and Molecular Biology. 11: 165-172. PMID 7519435 DOI: 10.1165/Ajrcmb.11.2.7519435  0.444
1994 Laskin JD, Heck DE, Laskin DL. Multifunctional role of nitric oxide in inflammation Trends in Endocrinology and Metabolism. 5: 377-382. DOI: 10.1016/1043-2760(94)90105-8  0.419
1994 Feder LS, Laskin DL. Regulation of hepatic endothelial cell and macrophage proliferation and nitric oxide production by GM-CSF, M-CSF, and IL-1β following acute endotoxemia Journal of Leukocyte Biology. 55: 507-513. DOI: 10.1002/Jlb.55.4.507  0.447
1993 Lavnikova N, Prokhorova S, Helyar L, Laskin DL. Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes, and highly enriched interstitial macrophages from rat lung. American Journal of Respiratory Cell and Molecular Biology. 8: 384-92. PMID 8476632 DOI: 10.1165/Ajrcmb/8.4.384  0.438
1993 Feder LS, Todaro JA, Laskin DL. Characterization of interleukin-1 and interleukin-6 production by hepatic endothelial cells and macrophages. Journal of Leukocyte Biology. 53: 126-32. PMID 8445325 DOI: 10.1002/Jlb.53.2.126  0.349
1993 Lavnikova N, Drapier JC, Laskin DL. A single exogenous stimulus activates resident rat macrophages for nitric oxide production and tumor cytotoxicity. Journal of Leukocyte Biology. 54: 322-8. PMID 8409754 DOI: 10.1002/Jlb.54.4.322  0.447
1993 Gardner CR, Laskin JD, Laskin DL. Platelet-activating factor-induced calcium mobilization and oxidative metabolism in hepatic macrophages and endothelial cells Journal of Leukocyte Biology. 53: 190-196. PMID 8383168 DOI: 10.1002/Jlb.53.2.190  0.362
1992 MacEachern L, Laskin DL. Increased production of tumor necrosis factor-alpha by bone marrow leukocytes following benzene treatment of mice. Toxicology and Applied Pharmacology. 113: 260-6. PMID 1561635 DOI: 10.1016/0041-008X(92)90123-A  0.325
1992 McCloskey TW, Todaro JA, Laskin DL. Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells. Hepatology (Baltimore, Md.). 16: 191-203. PMID 1319950 DOI: 10.1002/Hep.1840160130  0.407
1991 Laskin DL. Parenchymal and nonparenchymal cell interactions in hepatotoxicity. Advances in Experimental Medicine and Biology. 283: 499-505. PMID 2069021 DOI: 10.1007/978-1-4684-5877-0_66  0.324
1991 Laskin JD, Dokidis A, Sirak AA, Laskin DL. Distinct patterns of sulfated proteoglycan biosynthesis in human monocytes, granulocytes and myeloid leukemic cells Leukemia Research. 15: 515-523. PMID 1861534 DOI: 10.1016/0145-2126(91)90063-Y  0.313
1991 Laskin JD, Dokidis A, Gardner CR, Laskin DL. Changes in sulfated proteoglycan production after activation of rat liver macrophages Hepatology. 14: 306-312. PMID 1860687 DOI: 10.1002/Hep.1840140217  0.417
1991 Gardner CR, Wasserman AJ, Laskin DL. Liver macrophage-mediated cytotoxicity toward mastocytoma cells involves phagocytosis of tumor targets Hepatology. 14: 318-324. DOI: 10.1002/Hep.1840140219  0.399
1990 Reiners JJ, Cantu AR, Pavone A, Smith SC, Gardner CR, Laskin DL. Fluorescence assay for per-cell estimation of cytochrome P-450-dependent monooxygenase activities in keratinocyte suspensions and cultures. Analytical Biochemistry. 188: 317-24. PMID 2221380 DOI: 10.1016/0003-2697(90)90613-E  0.309
1990 Sirak AA, Laskin JD, Robertson FM, Laskin DL. Failure of F-Met-Leu-Phe to induce chemotaxis in differentiated promyelocytic (HL-60) leukemia cells. Journal of Leukocyte Biology. 48: 333-42. PMID 2168465 DOI: 10.1002/Jlb.48.4.333  0.358
1990 Laskin DL, Soltys RA, Berg RA, Riley DJ. Activation of neutrophils by factors released from alveolar macrophages stimulated with collagen-like polypeptides American Journal of Respiratory Cell and Molecular Biology. 2: 463-470. PMID 2160256 DOI: 10.1165/Ajrcmb/2.5.463  0.422
1989 Riley DJ, Berg RA, Soltys RA, Kerr JS, Guss HN, Curran SF, Laskin DL. Neutrophil response following intratracheal instillation of collagen peptides into rat lungs. Experimental Lung Research. 14: 549-63. PMID 3208719 DOI: 10.3109/01902148809087827  0.425
1989 Laskin DL, MacEachern L, Snyder R. Activation of bone marrow phagocytes following benzene treatment of mice. Environmental Health Perspectives. 82: 75-9. PMID 2676504 DOI: 10.1289/Ehp.898275  0.303
1988 Laskin DL, Robertson FM, Pilaro AM, Laskin JD. Activation of liver macrophages following phenobarbital treatment of rats. Hepatology (Baltimore, Md.). 8: 1051-5. PMID 2971014 DOI: 10.1002/Hep.1840080512  0.407
1988 Laskin DL, Sirak AA, Pilaro AM, Laskin JD. Functional and biochemical properties of rat Kupffer cells and peritoneal macrophages Journal of Leukocyte Biology. 44: 71-78. PMID 2841398 DOI: 10.1002/Jlb.44.2.71  0.422
1987 Laskin DL, Gardner CR, Laskin JD. Induction of chemotaxis in mouse peritoneal macrophages by activators of protein kinase C Journal of Leukocyte Biology. 41: 474-480. PMID 3036983 DOI: 10.1002/Jlb.41.6.474  0.413
1986 Laskin DL, Kimura T, Sakakibara S, Riley DJ, Berg RA. Chemotactic activity of collagen-like polypeptides for human peripheral blood neutrophils Journal of Leukocyte Biology. 39: 255-266. PMID 3456007 DOI: 10.1002/Jlb.39.3.255  0.322
1986 Laskin DL, Pilaro AM, Ji S. Potential role of activated macrophages in acetaminophen hepatotoxicity. II. Mechanism of macrophage accumulation and activation. Toxicology and Applied Pharmacology. 86: 216-26. PMID 3024357 DOI: 10.1016/0041-008X(86)90052-9  0.402
1986 Laskin DL, Pilaro AM. Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver. Toxicology and Applied Pharmacology. 86: 204-15. PMID 3024356 DOI: 10.1016/0041-008X(86)90051-7  0.399
1986 Pilaro AM, Laskin DL. Accumulation of activated mononuclear phagocytes in the liver following lipopolysaccharide treatment of rats. Journal of Leukocyte Biology. 40: 29-41. PMID 3011936 DOI: 10.1002/Jlb.40.1.29  0.373
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