Margaret M. Briehl - Publications

Affiliations: 
University of Arizona, Tucson, AZ 
Area:
Molecular Biology, Oncology, Cell Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Briehl MM. Oxygen in human health from life to death--An approach to teaching redox biology and signaling to graduate and medical students. Redox Biology. 5: 124-39. PMID 25912168 DOI: 10.1016/J.Redox.2015.04.002  0.342
2015 Jaramillo MC, Briehl MM, Batinic-Haberle I, Tome ME. Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells. Free Radical Biology & Medicine. 83: 89-100. PMID 25725417 DOI: 10.1016/J.Freeradbiomed.2015.01.031  0.782
2014 Briehl MM, Tome ME, Wilkinson ST, Jaramillo MC, Lee K. Mitochondria and redox homoeostasis as chemotherapeutic targets. Biochemical Society Transactions. 42: 939-44. PMID 25109983 DOI: 10.1042/Bst20140087  0.796
2014 Barr PM, Miller TP, Friedberg JW, Peterson DR, Baran AM, Herr M, Spier CM, Cui H, Roe DJ, Persky DO, Casulo C, Littleton J, Schwartz M, Puvvada S, Landowski TH, ... ... Briehl MM, et al. Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma. Blood. 124: 1259-65. PMID 25016003 DOI: 10.1182/Blood-2014-04-570044  0.413
2014 Lee K, Hart MR, Briehl MM, Mazar AP, Tome ME. The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma. International Journal of Oncology. 45: 439-47. PMID 24788952 DOI: 10.3892/Ijo.2014.2396  0.495
2014 Gustafson HL, Yao S, Goldman BH, Lee K, Spier CM, LeBlanc ML, Rimsza LM, Cerhan JR, Habermann TM, Link BK, Maurer MJ, Slager SL, Persky DO, Miller TP, Fisher RI, ... ... Briehl MM, et al. Genetic polymorphisms in oxidative stress-related genes are associated with outcomes following treatment for aggressive B-cell non-Hodgkin lymphoma. American Journal of Hematology. 89: 639-45. PMID 24633940 DOI: 10.1002/Ajh.23709  0.707
2013 Lee K, Briehl MM, Mazar AP, Batinic-Haberle I, Reboucas JS, Glinsmann-Gibson B, Rimsza LM, Tome ME. The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies. Free Radical Biology & Medicine. 60: 157-67. PMID 23416365 DOI: 10.1016/J.Freeradbiomed.2013.02.003  0.573
2013 Barr PM, Briehl MM, Bernstein SH, Friedberg JW, Baran A, Peterson DR, Persky DO, Casulo C, Herr MM, Littleton J, Cebula E, Schwartz M, Puvvada SD, Dorr RT, Fisher RI, et al. Redox Associated Gene Expression Predicts For Responses To The Pro-Oxidant Molecule Imexon In Relapsed and Refractory B-Cell Non-Hodgkin Lymphoma: Results Of a Multi-Center Phase II Study Blood. 122: 89-89. DOI: 10.1182/Blood.V122.21.89.89  0.421
2013 Jaramillo MC, Briehl MM, Batinic-Haberle I, Tome ME. Inhibition of the Electron Transport Chain Via the Pro-Oxidative Activity of Manganese Porphyrin-Based SOD Mimetics Modulates Bioenergetics and Enhances the Response to Chemotherapy Free Radical Biology and Medicine. 65: S25. DOI: 10.1016/J.Freeradbiomed.2013.10.443  0.722
2013 Briehl MM, Cui H, Roe DJ, Landowski TH. A Redox Score Obtained by Gene Expression Analyses Confirms a More Oxidized State in Lymphoma Compared to Non-neoplastic Lymph Nodes Free Radical Biology and Medicine. 65: S15-S16. DOI: 10.1016/J.Freeradbiomed.2013.10.416  0.304
2012 Wilkinson ST, Tome ME, Briehl MM. Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells. International Journal of Molecular Sciences. 13: 10212-28. PMID 22949856 DOI: 10.3390/Ijms130810212  0.756
2012 Tome ME, Lee K, Jaramillo MC, Briehl MM. Mitochondria are the primary source of the H(2)O(2) signal for glucocorticoid-induced apoptosis of lymphoma cells. Experimental and Therapeutic Medicine. 4: 237-242. PMID 22844350 DOI: 10.3892/Etm.2012.595  0.774
2012 Sertel S, Tome M, Briehl MM, Bauer J, Hock K, Plinkert PK, Efferth T. Factors determining sensitivity and resistance of tumor cells to arsenic trioxide. Plos One. 7: e35584. PMID 22590507 DOI: 10.1371/Journal.Pone.0035584  0.441
2012 Tome ME, Frye JB, Coyle DL, Jacobson EL, Samulitis BK, Dvorak K, Dorr RT, Briehl MM. Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance. Experimental and Therapeutic Medicine. 3: 845-852. PMID 22529877 DOI: 10.3892/Etm.2012.487  0.521
2012 Jaramillo MC, Briehl MM, Crapo JD, Batinic-Haberle I, Tome ME. Manganese porphyrin, MnTE-2-PyP 5+, acts as a pro-oxidant to potentiate glucocorticoid-induced apoptosis in lymphoma cells Free Radical Biology and Medicine. 52: 1272-1284. PMID 22330065 DOI: 10.1016/J.Freeradbiomed.2012.02.001  0.776
2012 Briehl MM, Gustafson HL, Lee K, Tome ME. Rapamycin Treatment of Mantle Cell LymphomaInhibits MTORC2 Signaling, Resulting in IncreasedMnSOD Expression and Hydrogen PeroxideGeneration Free Radical Biology and Medicine. 53: S39-S40. DOI: 10.1016/J.Freeradbiomed.2012.10.101  0.36
2011 Tome ME, Jaramillo MC, Briehl MM. Hydrogen peroxide signaling is required for glucocorticoid-induced apoptosis in lymphoma cells. Free Radical Biology & Medicine. 51: 2048-59. PMID 21964507 DOI: 10.1016/J.Freeradbiomed.2011.09.002  0.778
2011 Tardif HL, Tome ME, Briehl MM. Abstract A175: Role of MnSOD and hydrogen peroxide in rapamycin-induced cytostasis. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A175  0.501
2010 Wilkinson ST, Johnson DB, Tardif HL, Tome ME, Briehl MM. Increased cytochrome c correlates with poor survival in aggressive lymphoma. Oncology Letters. 1: 227-230. PMID 20798784 DOI: 10.3892/Ol_00000040  0.727
2010 Tardif HL, Yao S, Goldman BH, Spier CM, LeBlanc ML, Rimsza LM, Persky DO, Miller TP, Fisher RI, Ambrosone CB, Briehl MM. Genetic Polymorphisms In Oxidative Stress-Related Genes Correlated with Outcome Following Anthracycline-Based Therapy for Aggressive B-Cell Non-Hodgkin Lymphomas Blood. 116: 321-321. DOI: 10.1182/Blood.V116.21.321.321  0.386
2010 Tome ME, Jaramillo MC, Briehl MM. Glucocorticoid Resistance in Lymphoma Cells Mediated by Hydrogen Peroxide Removal and Disregulation of MAPK Signaling Free Radical Biology and Medicine. 49: S131. DOI: 10.1016/J.Freeradbiomed.2010.10.360  0.741
2010 Jaramillo MC, Briehl MM, Tome ME. Manganese Porphyrin Glutathionylates the p65 Subunit of NF-κB to Potentiate Glucocorticoid-induced Apoptosis in Lymphoma Free Radical Biology and Medicine. 49: S63. DOI: 10.1016/J.Freeradbiomed.2010.10.149  0.729
2009 Skalska J, Brookes PS, Nadtochiy SM, Hilchey SP, Jordan CT, Guzman ML, Maggirwar SB, Briehl MM, Bernstein SH. Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide. Plos One. 4: e8115. PMID 19956548 DOI: 10.1371/Journal.Pone.0008115  0.44
2009 Jaramillo MC, Frye JB, Crapo JD, Briehl MM, Tome ME. Increased manganese superoxide dismutase expression or treatment with manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells Cancer Research. 69: 5450-5457. PMID 19549914 DOI: 10.1158/0008-5472.Can-08-4031  0.777
2009 Skalska J, Brookes PS, Nadtochy SM, Hilchey S, Jordan CT, Guzman ML, Maggirwar S, Briehl MM, Bernstein SH. Modulation of Cell Surface Protein Free Thiols; A Potential Novel Mechanism of Action of the Sesquiterpene Lactone Parthenolide in Non-Hodgkin's Lymphoma. Blood. 114: 3774-3774. DOI: 10.1182/Blood.V114.22.3774.3774  0.447
2009 Tardif HL, Tome ME, Briehl MM. Abstract C55: Involvement of oxidative stress in the antitumor effect of mTOR inhibitors in mantle cell lymphoma Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C55  0.469
2006 Tome ME, Johnson DB, Samulitis BK, Dorr RT, Briehl MM. Glucose 6-phosphate dehydrogenase overexpression models glucose deprivation and sensitizes lymphoma cells to apoptosis. Antioxidants & Redox Signaling. 8: 1315-27. PMID 16910779 DOI: 10.1089/Ars.2006.8.1315  0.521
2006 Glinsmann-Gibson BJ, Cycon KA, Murphy SP, Miller TP, Grogan TM, Tome ME, Briehl MM, Rimsza LM. Induced Major Histocompatibility Class II (MHCII) Expression Does Not Alter Chemosensitivity, Radiosensitivity, Redox Potential, or Proliferation Rate in a CIITA-Transfected Diffuse Large B Cell Lymphoma (DLBCL) Cell Line. Blood. 108: 2040-2040. DOI: 10.1182/Blood.V108.11.2040.2040  0.445
2005 Tome ME, Johnson DB, Rimsza LM, Roberts RA, Grogan TM, Miller TP, Oberley LW, Briehl MM. A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis. Blood. 106: 3594-601. PMID 16081686 DOI: 10.1182/Blood-2005-02-0487  0.384
2005 Efferth T, Rauh R, Kahl S, Tomicic M, Böchzelt H, Tome ME, Briehl MM, Bauer R, Kaina B. Molecular modes of action of cantharidin in tumor cells. Biochemical Pharmacology. 69: 811-8. PMID 15710358 DOI: 10.1016/J.Bcp.2004.12.003  0.468
2005 Tome ME, Briehl MM, Lutz NW. Increasing the antioxidant defense in WEHI7.2 cells results in a more tumor-like metabolic profile. International Journal of Molecular Medicine. 15: 497-501. PMID 15702245 DOI: 10.3892/Ijmm.15.3.497  0.403
2004 Tome ME, Lutz NW, Briehl MM. Overexpression of catalase or Bcl-2 alters glucose and energy metabolism concomitant with dexamethasone resistance. Biochimica Et Biophysica Acta. 1693: 57-72. PMID 15276325 DOI: 10.1016/J.Bbamcr.2004.05.004  0.472
2004 Butts BD, Tran NL, Briehl MM. Identification of a functional peroxisome proliferator activated receptor response element in the 3' untranslated region of the human bcl-2 gene. International Journal of Oncology. 24: 1305-10. PMID 15067355  0.738
2003 Tome ME, Lutz NW, Briehl MM. Overexpression of catalase or Bcl-2 delays or prevents alterations in phospholipid metabolism during glucocorticoid-induced apoptosis in WEHI7.2 cells. Biochimica Et Biophysica Acta. 1642: 149-62. PMID 14572898 DOI: 10.1016/J.Bbamcr.2003.08.002  0.505
2003 Efferth T, Briehl MM, Tome ME. Role of antioxidant genes for the activity of artesunate against tumor cells. International Journal of Oncology. 23: 1231-5. PMID 12964009 DOI: 10.3892/Ijo.23.4.1231  0.459
2003 Butts BD, Kwei KA, Bowden GT, Briehl MM. Elevated basal reactive oxygen species and phospho-Akt in murine keratinocytes resistant to ultraviolet B-induced apoptosis. Molecular Carcinogenesis. 37: 149-57. PMID 12884366 DOI: 10.1002/Mc.10131  0.786
2002 Dvorakova K, Payne CM, Tome ME, Briehl MM, Vasquez MA, Waltmire CN, Coon A, Dorr RT. Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells. Molecular Cancer Therapeutics. 1: 185-95. PMID 12467213  0.432
2002 Lutz NW, Tome ME, Aiken NR, Briehl MM. Changes in phosphate metabolism in thymoma cells suggest mechanisms for resistance to dexamethasone-induced apoptosis. A 31P NMR spectroscopic study of call extracts Nmr in Biomedicine. 15: 356-366. PMID 12203227 DOI: 10.1002/Nbm.790  0.517
2001 Gupta A, Butts B, Kwei KA, Dvorakova K, Stratton SP, Briehl MM, Bowden GT. Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression. Cancer Letters. 173: 115-25. PMID 11597785 DOI: 10.1016/S0304-3835(01)00656-5  0.764
2001 Tome ME, Briehl MM. Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis. Cell Death and Differentiation. 8: 953-61. PMID 11526450 DOI: 10.1038/Sj.Cdd.4400904  0.55
2001 Dvorakova K, Waltmire CN, Payne CM, Tome ME, Briehl MM, Dorr RT. Induction of mitochondrial changes in myeloma cells by imexon. Blood. 97: 3544-51. PMID 11369649 DOI: 10.1182/Blood.V97.11.3544  0.524
2000 Dvorakova K, Payne CM, Tome ME, Briehl MM, McClure T, Dorr RT. Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent imexon. Biochemical Pharmacology. 60: 749-58. PMID 10930529 DOI: 10.1016/S0006-2952(00)00380-4  0.503
2000 Siemankowski LM, Morreale J, Butts BD, Briehl MM. Increased tumor necrosis factor-alpha sensitivity of MCF-7 cells transfected with NAD(P)H:quinone reductase. Cancer Research. 60: 3638-44. PMID 10910079  0.776
1999 Siemankowski LM, Morreale J, Briehl MM. Antioxidant defenses in the TNF-treated MCF-7 cells: selective increase in MnSOD. Free Radical Biology & Medicine. 26: 919-24. PMID 10232835 DOI: 10.1016/S0891-5849(98)00273-1  0.488
1999 Yan Q, Briehl M, Crowley CL, Payne CM, Bernstein H, Bernstein C. The NAD+ precursors, nicotinic acid and nicotinamide upregulate glyceraldehyde-3-phosphate dehydrogenase and glucose-6-phosphate dehydrogenase mRNA in Jurkat cells. Biochemical and Biophysical Research Communications. 255: 133-6. PMID 10082668 DOI: 10.1006/Bbrc.1999.0154  0.36
1998 Payne CM, Crowley C, Washo-Stultz D, Briehl M, Bernstein H, Bernstein C, Beard S, Holubec H, Warneke J. The stress-response proteins poly(ADP-ribose) polymerase and NF-kappaB protect against bile salt-induced apoptosis. Cell Death and Differentiation. 5: 623-36. PMID 10200517 DOI: 10.1038/Sj.Cdd.4400395  0.465
1996 Powis G, Briehl M, Oblong J. Redox signalling and the control of cell growth and death. Pharmacology & Therapeutics. 68: 149-73. PMID 8604436 DOI: 10.1016/0163-7258(95)02004-7  0.404
1993 Flomerfelt FA, Briehl MM, Dowd DR, Dieken ES, Miesfeld RL. Elevated glutathione S-transferase gene expression is an early event during steroid-induced lymphocyte apoptosis. Journal of Cellular Physiology. 154: 573-81. PMID 8382211 DOI: 10.1002/Jcp.1041540316  0.485
1992 Briehl MM, Miesfeld RL. Isolation and characterization of transcripts induced by androgen withdrawal and apoptotic cell death in the rat ventral prostate. Molecular Endocrinology (Baltimore, Md.). 5: 1381-8. PMID 1723140 DOI: 10.1210/Mend-5-10-1381  0.368
1990 Briehl MM, Flomerfelt FA, Wu XP, Miesfeld RL. Transcriptional analyses of steroid-regulated gene networks. Molecular Endocrinology (Baltimore, Md.). 4: 287-94. PMID 2330007 DOI: 10.1210/Mend-4-2-287  0.329
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