Charles Giardina - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Cell Biology, Molecular Biology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ideta T, Li B, Flynn C, Igarashi Y, Lowman G, Looney T, Devers TJ, Birk J, Forouhar F, Giardina C, Rosenberg DW. The Epithelial-Stromal Microenvironment in Early Colonic Neoplasia. Molecular Cancer Research : McR. PMID 34670862 DOI: 10.1158/1541-7786.MCR-21-0202  0.363
2019 Hoang TH, Zhao Y, Lam Y, Piekos S, Han YC, Reilly C, Joshi P, Hong SH, Sung CO, Giardina C, Shin DG. BioTarget: A Computational Framework Identifying Cancer Type Specific Transcriptional Targets of Immune Response Pathways. Scientific Reports. 9: 9029. PMID 31227749 DOI: 10.1038/S41598-019-45304-X  0.381
2019 Huang H, Aladelokun O, Ideta T, Giardina C, Ellis LM, Rosenberg DW. Inhibition of PGE/EP4 receptor signaling enhances oxaliplatin efficacy in resistant colon cancer cells through modulation of oxidative stress. Scientific Reports. 9: 4954. PMID 30894570 DOI: 10.1038/S41598-019-40848-4  0.482
2018 Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanandan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C. Spindle assembly disruption and cancer cell apoptosis with a CLTC-binding compound. Molecular Cancer Research : McR. PMID 29769406 DOI: 10.1158/1541-7786.Mcr-18-0178  0.437
2017 Harrison LE, Bleiler M, Giardina C. A look into centrosome abnormalities in colon cancer cells, how they arise and how they might be targeted therapeutically. Biochemical Pharmacology. PMID 29128368 DOI: 10.1016/J.Bcp.2017.11.003  0.365
2017 Zhao Y, Hoang TH, Joshi P, Hong SH, Giardina C, Shin DG. A Route-Based Pathway Analysis Framework Integrating Mutation Information and Gene Expression Data. Methods (San Diego, Calif.). PMID 28647608 DOI: 10.1016/J.Ymeth.2017.06.016  0.312
2016 Hanley MP, Kadaveru K, Perret C, Giardina C, Rosenberg DW. Dietary methyl donor depletion suppresses intestinal adenoma development. Cancer Prevention Research (Philadelphia, Pa.). PMID 27530130 DOI: 10.1158/1940-6207.Capr-16-0042  0.363
2016 Mo A, Jackson S, Varma K, Carpino A, Giardina C, Devers TJ, Rosenberg DW. Distinct Transcriptional Changes and Epithelial-stromal Interactions are Altered in Early Stage Colon Cancer Development. Molecular Cancer Research : McR. PMID 27353028 DOI: 10.1158/1541-7786.Mcr-16-0156  0.425
2016 Chopra A, Bond MJ, Bleiler M, Yeagley M, Wright D, Giardina C. Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301. Plos One. 11: e0153818. PMID 27097159 DOI: 10.1371/Journal.Pone.0153818  0.461
2016 Mo A, Jackson S, Varma K, Carpino A, Giardina C, Devers TJ, Rosenberg DW. Abstract 4082: Epithelial-stromal interactions are altered at the earliest stages of colon cancer development Cancer Research. 76: 4082-4082. DOI: 10.1158/1538-7445.Am2016-4082  0.4
2015 Giardina C, Nakanishi M, Khan A, Kuratnik A, Xu W, Brenner B, Rosenberg DW. Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas. Cancer Prevention Research (Philadelphia, Pa.). 8: 387-99. PMID 25873367 DOI: 10.1158/1940-6207.Capr-14-0371  0.441
2015 Cao L, Kuratnik A, Xu W, Gibson JD, Kolling F, Falcone ER, Ammar M, Van Heyst MD, Wright DL, Nelson CE, Giardina C. Development of intestinal organoids as tissue surrogates: cell composition and the epigenetic control of differentiation. Molecular Carcinogenesis. 54: 189-202. PMID 24115167 DOI: 10.1002/Mc.22089  0.428
2015 Chopra A, Anderson A, Rosenberg D, Giardina C. Abstract 3781: Effects of a novel microtubule inhibitor, AK301 on Apc heterozygote colon cells Cancer Research. 75: 3781-3781. DOI: 10.1158/1538-7445.Am2015-3781  0.377
2014 Wright KT, Giardina C, Vella AT. Therapeutic targeting of the inflammome. Biochemical Pharmacology. 92: 184-91. PMID 25204592 DOI: 10.1016/J.Bcp.2014.08.027  0.3
2014 Ononye SN, Vanheyst MD, Giardina C, Wright DL, Anderson AC. Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells. Bioorganic & Medicinal Chemistry. 22: 2188-93. PMID 24613456 DOI: 10.1016/J.Bmc.2014.02.018  0.384
2014 Chopra A, Anderson A, Giardina C. Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis. The Journal of Biological Chemistry. 289: 2978-91. PMID 24338023 DOI: 10.1074/Jbc.M113.499319  0.448
2013 Kuratnik A, Giardina C. Intestinal organoids as tissue surrogates for toxicological and pharmacological studies. Biochemical Pharmacology. 85: 1721-6. PMID 23623789 DOI: 10.1016/J.Bcp.2013.04.016  0.335
2013 Dai B, Giardina C, Rasmussen TP. Quantitation of nucleosome acetylation and other histone posttranslational modifications using microscale NU-ELISA. Methods in Molecular Biology (Clifton, N.J.). 981: 167-76. PMID 23381861 DOI: 10.1007/978-1-62703-305-3_13  0.321
2013 Chopra AS, Kuratnik A, Scocchera EW, Wright DL, Giardina C. Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands. Cancer Biology & Therapy. 14: 436-49. PMID 23377828 DOI: 10.4161/Cbt.23787  0.456
2013 Fuller AM, Giardina C, Hightower LE, Perdrizet GA, Tierney CA. Hyperbaric oxygen preconditioning protects skin from UV-A damage. Cell Stress & Chaperones. 18: 97-107. PMID 22855227 DOI: 10.1007/S12192-012-0362-2  0.315
2012 Kuratnik A, Senapati VE, Verma R, Mellone BG, Vella AT, Giardina C. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical Pharmacology. 83: 1217-28. PMID 22306067 DOI: 10.1016/J.Bcp.2012.01.024  0.442
2012 Rigatti MJ, Verma R, Belinsky GS, Rosenberg DW, Giardina C. Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells. Molecular Carcinogenesis. 51: 363-78. PMID 21557332 DOI: 10.1002/Mc.20795  0.465
2011 Montrose DC, Horelik NA, Madigan JP, Stoner GD, Wang LS, Bruno RS, Park HJ, Giardina C, Rosenberg DW. Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis. 32: 343-50. PMID 21098643 DOI: 10.1093/Carcin/Bgq248  0.328
2011 Cao L, Gibson JD, Miyamoto S, Sail V, Verma R, Rosenberg DW, Nelson CE, Giardina C. Intestinal lineage commitment of embryonic stem cells. Differentiation; Research in Biological Diversity. 81: 1-10. PMID 20934799 DOI: 10.1016/J.Diff.2010.09.182  0.383
2011 Perdrizet G, Godman C, Giardina C, Hightower L. Human Microvascular Endothelial Cells Treated With Hyperbaric Oxygen Become Resistant To Lethal Oxidation And have Increased Expression Of Cytoprotective Genes Journal of Surgical Research. 165: 265. DOI: 10.1016/J.Jss.2010.11.446  0.763
2010 Ju J, Naura AS, Errami Y, Zerfaoui M, Kim H, Kim JG, Abd Elmageed ZY, Abdel-Mageed AB, Giardina C, Beg AA, Smulson ME, Boulares AH. Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment. The Journal of Biological Chemistry. 285: 41152-60. PMID 20966071 DOI: 10.1074/Jbc.M110.158352  0.333
2010 Godman CA, Joshi R, Giardina C, Perdrizet G, Hightower LE. Hyperbaric oxygen treatment induces antioxidant gene expression. Annals of the New York Academy of Sciences. 1197: 178-83. PMID 20536847 DOI: 10.1111/J.1749-6632.2009.05393.X  0.77
2010 Godman CA, Chheda KP, Hightower LE, Perdrizet G, Shin DG, Giardina C. Hyperbaric oxygen induces a cytoprotective and angiogenic response in human microvascular endothelial cells. Cell Stress & Chaperones. 15: 431-42. PMID 19949909 DOI: 10.1007/S12192-009-0159-0  0.78
2010 Verma R, Rigatti MJ, Belinsky GS, Godman CA, Giardina C. DNA damage response to the Mdm2 inhibitor nutlin-3. Biochemical Pharmacology. 79: 565-74. PMID 19788889 DOI: 10.1016/J.Bcp.2009.09.020  0.761
2009 Noonan EJ, Place RF, Pookot D, Basak S, Whitson JM, Hirata H, Giardina C, Dahiya R. miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene. 28: 1714-24. PMID 19252524 DOI: 10.1038/Onc.2009.19  0.685
2009 Rosenberg DW, Giardina C, Tanaka T. Mouse models for the study of colon carcinogenesis. Carcinogenesis. 30: 183-96. PMID 19037092 DOI: 10.1093/Carcin/Bgn267  0.345
2008 Spurling CC, Suhl JA, Boucher N, Nelson CE, Rosenberg DW, Giardina C. The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells. Nutrition and Cancer. 60: 692-702. PMID 18791934 DOI: 10.1080/01635580802008278  0.42
2008 Godman CA, Joshi R, Tierney BR, Greenspan E, Rasmussen TP, Wang HW, Shin DG, Rosenberg DW, Giardina C. HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biology & Therapy. 7: 1570-80. PMID 18769117 DOI: 10.4161/Cbt.7.10.6561  0.775
2008 Noonan E, Giardina C, Hightower L. Hsp70B' and Hsp72 form a complex in stressed human colon cells and each contributes to cytoprotection. Experimental Cell Research. 314: 2468-76. PMID 18579131 DOI: 10.1016/J.Yexcr.2008.05.002  0.386
2008 Spurling CC, Godman CA, Noonan EJ, Rasmussen TP, Rosenberg DW, Giardina C. HDAC3 overexpression and colon cancer cell proliferation and differentiation. Molecular Carcinogenesis. 47: 137-47. PMID 17849419 DOI: 10.1002/Mc.20373  0.799
2007 Nakanishi M, Ménoret A, Belinsky GS, Giardina C, Godman CA, Vella AT, Rosenberg DW. Utilizing endoscopic technology to reveal real-time proteomic alterations in response to chemoprevention. Proteomics. Clinical Applications. 1: 1660-6. PMID 21136663 DOI: 10.1002/Prca.200700545  0.75
2007 Noonan EJ, Place RF, Giardina C, Hightower LE. Hsp70B' regulation and function. Cell Stress & Chaperones. 12: 393-402. PMID 18229458 DOI: 10.1379/Csc-278E.1  0.723
2007 Noonan EJ, Place RF, Giardina C, Hightower LE. Hsp70B' regulation and function. Cell Stress & Chaperones. 12: 219-29. PMID 17915554 DOI: 10.1379/CSC-278.1  0.707
2007 Belinsky GS, Rajan TV, Saria EA, Giardina C, Rosenberg DW. Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth. Molecular Carcinogenesis. 46: 106-16. PMID 17091473 DOI: 10.1002/Mc.20271  0.402
2007 Noonan EJ, Place RF, Rasoulpour RJ, Giardina C, Hightower LE. Cell number-dependent regulation of Hsp70B' expression: evidence of an extracellular regulator. Journal of Cellular Physiology. 210: 201-11. PMID 17044073 DOI: 10.1002/Jcp.20875  0.732
2006 Aizu W, Belinsky GS, Flynn C, Noonan EJ, Boes CC, Godman CA, Doshi B, Nambiar PR, Rosenberg DW, Giardina C. Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors. Biochemical Pharmacology. 72: 981-91. PMID 16949053 DOI: 10.1016/J.Bcp.2006.07.009  0.784
2005 Place RF, Noonan EJ, Giardina C. HDACs and the senescent phenotype of WI-38 cells. Bmc Cell Biology. 6: 37. PMID 16250917 DOI: 10.1186/1471-2121-6-37  0.731
2005 Place RF, Noonan EJ, Giardina C. HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. Biochemical Pharmacology. 70: 394-406. PMID 15950952 DOI: 10.1016/J.Bcp.2005.04.030  0.725
2005 Dong M, Johnson M, Rezaie A, Ilsley JNM, Nakanishi M, Sanders MM, Forouhar F, Levine J, Montrose DC, Giardina C, Rosenberg DW. Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis Clinical Cancer Research. 11: 2265-2271. PMID 15788676 DOI: 10.1158/1078-0432.Ccr-04-1079  0.425
2005 Tong X, Yin L, Joshi S, Rosenberg DW, Giardina C. Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors. The Journal of Biological Chemistry. 280: 15503-9. PMID 15713675 DOI: 10.1074/Jbc.M411978200  0.456
2004 Tong X, Yin L, Washington R, Rosenberg DW, Giardina C. The p50-p50 NF-κB complex as a stimulus-specific repressor of gene activation Molecular and Cellular Biochemistry. 265: 171-183. PMID 15543947 DOI: 10.1023/B:Mcbi.0000044394.66951.4D  0.353
2004 Dong M, Guda K, Nambiar PR, Nakanishi M, Lichtler AC, Nishikawa M, Giardina C, Rosenberg DW. Azoxymethane-induced pre-adipocyte factor 1 (Pref-1) functions as a differentiation inhibitor in colonic epithelial cells. Carcinogenesis. 25: 2239-46. PMID 15297369 DOI: 10.1093/Carcin/Bgh237  0.452
2004 Tong X, Yin L, Giardina C. Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. Biochemical and Biophysical Research Communications. 317: 463-71. PMID 15063780 DOI: 10.1016/J.Bbrc.2004.03.066  0.443
2004 Thibodeau MS, Giardina C, Knecht DA, Helble J, Hubbard AK. Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 34-48. PMID 15056807 DOI: 10.1093/Toxsci/Kfh121  0.368
2003 Aizu W, Guda K, Nambiar P, Xin T, Thibodeau M, Rosenberg DW, Giardina C. p53 and its co-activator p300 are inversely regulated in the mouse colon in response to carcinogen. Toxicology Letters. 144: 213-24. PMID 12927365 DOI: 10.1016/S0378-4274(03)00221-2  0.391
2003 Thibodeau M, Giardina C, Hubbard AK. Silica-induced caspase activation in mouse alveolar macrophages is dependent upon mitochondrial integrity and aspartic proteolysis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 91-101. PMID 12857937 DOI: 10.1093/Toxsci/Kfg178  0.313
2003 Place RF, Haspeslagh D, Giardina C. Induced stabilization of IkappaBalpha can facilitate its re-synthesis and prevent sequential degradation. Journal of Cellular Physiology. 195: 470-8. PMID 12704657 DOI: 10.1002/Jcp.10262  0.709
2003 Dong M, Guda K, Nambiar PR, Rezaie A, Belinsky GS, Lambeau G, Giardina C, Rosenberg DW. Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis. Carcinogenesis. 24: 307-15. PMID 12584182 DOI: 10.1093/Carcin/24.2.307  0.411
2002 Giardina C, Hubbard AK. Growing old with nuclear factor-kappaB. Cell Stress & Chaperones. 7: 207-12. PMID 12380689 DOI: 10.1379/1466-1268(2002)007<0207:Gownfb>2.0.Co;2  0.31
2001 Yin L, Laevsky G, Giardina C. Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. The Journal of Biological Chemistry. 276: 44641-6. PMID 11572859 DOI: 10.1074/Jbc.M105170200  0.392
2001 Guda K, Giardina C, Nambiar P, Cui H, Rosenberg DW. Aberrant transforming growth factor-beta signaling in azoxymethane-induced mouse colon tumors. Molecular Carcinogenesis. 31: 204-13. PMID 11536370 DOI: 10.1002/Mc.1055  0.311
2001 Place RF, Haspeslagh D, Hubbard AK, Giardina C. Cytokine-induced stabilization of newly synthesized I(kappa)B-alpha. Biochemical and Biophysical Research Communications. 283: 813-20. PMID 11350057 DOI: 10.1006/Bbrc.2001.4883  0.673
2001 Yin L, Hubbard AK, Giardina C. NF-kappa B regulates transcription of the mouse telomerase catalytic subunit. The Journal of Biological Chemistry. 275: 36671-5. PMID 10970902 DOI: 10.1074/Jbc.M007378200  0.358
2001 Hubbard AK, Thibodeau M, Giardina C. Cellular and Molecular Mechanisms Regulating Silica-Induced Adhesion Molecule Expression in Mice Journal of Environmental Pathology, Toxicology and Oncology. 20: 8. DOI: 10.1615/Jenvironpatholtoxicoloncol.V20.Isuppl.1.40  0.412
2000 Inan MS, Tolmacheva V, Wang QS, Rosenberg DW, Giardina C. Transcription factor NF-kappaB participates in regulation of epithelial cell turnover in the colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G1282-91. PMID 11093952 DOI: 10.1152/Ajpgi.2000.279.6.G1282  0.439
2000 Inan MS, Place R, Tolmacheva V, Wang QS, Hubbard AK, Rosenberg DW, Giardina C. IkappaBbeta-related proteins in normal and transformed colonic epithelial cells. Molecular Carcinogenesis. 29: 25-36. PMID 11020244 DOI: 10.1002/1098-2744(200009)29:1<25::Aid-Mc4>3.0.Co;2-A  0.742
2000 Crowthers KC, Kline V, Giardina C, Lynes MA. Augmented humoral immune function in metallothionein-null mice. Toxicology and Applied Pharmacology. 166: 161-72. PMID 10906280 DOI: 10.1006/Taap.2000.8961  0.31
2000 Boulares AH, Giardina C, Inan MS, Khairallah EA, Cohen SD. Acetaminophen inhibits NF-kappaB activation by interfering with the oxidant signal in murine Hepa 1-6 cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 55: 370-5. PMID 10828269 DOI: 10.1093/Toxsci/55.2.370  0.37
2000 Inan MS, Rasoulpour RJ, Yin L, Hubbard AK, Rosenberg DW, Giardina C. The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. Gastroenterology. 118: 724-34. PMID 10734024 DOI: 10.1016/S0016-5085(00)70142-9  0.357
2000 Hubbard AK, Giardina C. Regulation of ICAM-1 expression in mouse macrophages. Inflammation. 24: 115-25. PMID 10718114 DOI: 10.1023/A:1007029409521  0.357
1999 Boulares HA, Giardina C, Navarro CL, Khairallah EA, Cohen SD. Modulation of serum growth factor signal transduction in Hepa 1-6 cells by acetaminophen: an inhibition of c-myc expression, NF-kappaB activation, and Raf-1 kinase activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 48: 264-74. PMID 10353317 DOI: 10.1093/Toxsci/48.2.264  0.408
1999 Giardina C, Boulares H, Inan MS. NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species. Biochimica Et Biophysica Acta. 1448: 425-38. PMID 9990295 DOI: 10.1016/S0167-4889(98)00156-6  0.432
1998 Giardina C, Inan MS. Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells. Biochimica Et Biophysica Acta. 1401: 277-88. PMID 9540818 DOI: 10.1016/S0167-4889(97)00140-7  0.334
1995 O'Brien T, Wilkins RC, Giardina C, Lis JT. Distribution of GAGA protein on Drosophila genes in vivo. Genes & Development. 9: 1098-110. PMID 7744251 DOI: 10.1101/Gad.9.9.1098  0.33
1995 Giardina C, Lis JT. Sodium salicylate and yeast heat shock gene transcription. The Journal of Biological Chemistry. 270: 10369-72. PMID 7737966 DOI: 10.1074/Jbc.270.18.10369  0.357
1992 Giardina C, Pérez-Riba M, Lis JT. Promoter melting and TFIID complexes on Drosophila genes in vivo. Genes & Development. 6: 2190-200. PMID 1427079 DOI: 10.1101/Gad.6.11.2190  0.373
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