| Year |
Citation |
Score |
| 2023 |
Bixby B, Vrba L, Lenka J, Oshiro M, Watts GS, Hughes T, Erickson H, Chopra M, Knepler JL, Knox KS, Jarnagin L, Alalawi R, Kala M, Bernert R, Routh J, ... ... Futscher BW, et al. Cell-Free DNA Methylation Analysis as a Marker of Malignancy in Pleural Fluid. Research Square. PMID 37886511 DOI: 10.21203/rs.3.rs-3390107/v1 |
0.722 |
|
| 2022 |
Vrba L, Futscher BW, Oshiro M, Watts GS, Menashi E, Hu C, Hammad H, Pennington DR, Golconda U, Gavini H, Roe DJ, Shroff RT, Nelson MA. Liquid biopsy, using a novel DNA methylation signature, distinguishes pancreatic adenocarcinoma from benign pancreatic disease. Clinical Epigenetics. 14: 28. PMID 35193708 DOI: 10.1186/s13148-022-01246-2 |
0.75 |
|
| 2020 |
Munugala N, Hammad H, Vrba L, Oshiro M, Wertheim B, Roe D, Gavini H, Latura L, Pennington D, Dalgai S, Babiker HM, Elquza E, Scott AJ, Nelson M, Futscher BW, et al. Detection of pancreatic cancer using a novel blood-based DNA methylation signature. Journal of Clinical Oncology. 38: e15546-e15546. DOI: 10.1200/Jco.2020.38.15_Suppl.E15546 |
0.754 |
|
| 2019 |
Vrba L, Futscher BW. DNA methylation changes in biomarker loci occur early in cancer progression. F1000research. 8: 2106. PMID 32047604 DOI: 10.12688/F1000Research.21584.2 |
0.441 |
|
| 2019 |
Vrba L, Oshiro MM, Kim SS, Garland LL, Placencia C, Mahadevan D, Nelson MA, Futscher BW. DNA methylation biomarkers discovered detect cancer in liquid biopsies from non-small cell lung cancer patients. Epigenetics. 1-12. PMID 31775567 DOI: 10.1080/15592294.2019.1695333 |
0.773 |
|
| 2019 |
Vrba L, Futscher BW. DNA methylation changes in biomarker loci occur early in cancer progression [version 1; peer review: 2 approved] F1000research. 8: 2106. DOI: 10.12688/F1000Research.21584.1 |
0.423 |
|
| 2018 |
Vrba L, Futscher BW. Epigenetic silencing of lncRNA in 16 TCGA cancer types. F1000research. 7: 211. PMID 29707199 DOI: 10.12688/F1000Research.13944.1 |
0.515 |
|
| 2017 |
Vrba L, Futscher BW. A suite of DNA methylation markers that can detect most common human cancers. Epigenetics. 1-38. PMID 29212414 DOI: 10.1080/15592294.2017.1412907 |
0.482 |
|
| 2017 |
Vrba L, Futscher BW. Epigenetic Silencing of Is an Early Event in Cancer and Is Associated with Luminal, Receptor Positive Breast Tumor Subtypes. Journal of Breast Cancer. 20: 198-202. PMID 28690657 DOI: 10.4048/Jbc.2017.20.2.198 |
0.463 |
|
| 2016 |
Black SA, Nelson AC, Gurule NJ, Futscher BW, Lyons TR. Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression. Oncogene. PMID 27065336 DOI: 10.1038/Onc.2016.49 |
0.357 |
|
| 2016 |
Black S, Nelson A, Gurule N, Futscher B, Lyons TR. Abstract B15: Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B15 |
0.383 |
|
| 2016 |
Black S, Nelson A, Gurule N, Futscher B, Lyons T. Abstract PR10: Silencing of semaphorin 7a attenuates breast tumor progression Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-Pr10 |
0.399 |
|
| 2015 |
Vrba L, Garbe JC, Stampfer MR, Futscher BW. A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers. Epigenetics. 10: 1074-83. PMID 26646903 DOI: 10.1080/15592294.2015.1106673 |
0.544 |
|
| 2015 |
Lee JK, Garbe JC, Vrba L, Miyano M, Futscher BW, Stampfer MR, LaBarge MA. Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells. Frontiers in Cell and Developmental Biology. 3: 13. PMID 25815289 DOI: 10.3389/Fcell.2015.00013 |
0.412 |
|
| 2015 |
Lang J, Zhu W, Nokes B, Sheth G, Novak P, Fuchs L, Watts G, Futscher B, Mineyev N, Ring A, LeBeau L, Nagle R, Cranmer L. Characterization of a novel radiation-induced sarcoma cell line. Journal of Surgical Oncology. 111: 669-82. PMID 25644184 DOI: 10.1002/Jso.23860 |
0.321 |
|
| 2015 |
Muñoz-Rodríguez JL, Vrba L, Hu C, Thompson PA, Martinez ME, Futscher BW. Abstract A82: Identifying differentially expressed microRNAs as investigational tools in postpartum breast cancer in Hispanic women Cancer Epidemiology, Biomarkers & Prevention. 24. DOI: 10.1158/1538-7755.Disp14-A82 |
0.315 |
|
| 2015 |
Lyons TR, Black SA, Futscher BW, Borges VF, Schedin PJ. Abstract P1-07-11: Promotion of lymphangiogenesis by postpartum breast tumor cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-11 |
0.421 |
|
| 2015 |
Rheinheimer BA, Vrba L, Futscher BW, Heimark RL. Abstract A79: Post-transcriptional regulatory networks of pancreatic tumor invasion Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A79 |
0.411 |
|
| 2014 |
Garbe JC, Vrba L, Sputova K, Fuchs L, Novak P, Brothman AR, Jackson M, Chin K, LaBarge MA, Watts G, Futscher BW, Stampfer MR. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle (Georgetown, Tex.). 13: 3423-35. PMID 25485586 DOI: 10.4161/15384101.2014.954456 |
0.36 |
|
| 2014 |
Severson PL, Vrba L, Stampfer MR, Futscher BW. Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 775: 48-54. PMID 25435355 DOI: 10.1016/J.Mrgentox.2014.10.011 |
0.728 |
|
| 2014 |
Vorrink SU, Severson PL, Kulak MV, Futscher BW, Domann FE. Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicology and Applied Pharmacology. 274: 408-16. PMID 24355420 DOI: 10.1016/J.Taap.2013.12.002 |
0.732 |
|
| 2014 |
Clarke JD, Novak P, Lake AD, Shipkova P, Aranibar N, Robertson D, Severson PL, Reily MD, Futscher BW, Lehman-McKeeman LD, Cherrington NJ. Characterization of hepatocellular carcinoma related genes and metabolites in human nonalcoholic fatty liver disease. Digestive Diseases and Sciences. 59: 365-74. PMID 24048683 DOI: 10.1007/S10620-013-2873-9 |
0.677 |
|
| 2014 |
Munoz-Rodriguez JL, Vrba L, Hu C, Thompson-Carino PA, Martinez ME, Futscher BW. Abstract C74: Epigenetic changes in postpartum breast cancer amongst Hispanic women Cancer Epidemiology, Biomarkers & Prevention. 23. DOI: 10.1158/1538-7755.Disp13-C74 |
0.376 |
|
| 2014 |
Rheinheimer BA, Vrba L, Futscher BW, Heimark RL. Abstract 127: Alternative transcription of the SLIT2/mir-218-1 signaling axis mediates pancreatic cancer invasion through the regulation of invadopodia Cancer Research. 74: 127-127. DOI: 10.1158/1538-7445.Am2014-127 |
0.364 |
|
| 2014 |
Lang JE, Nokes B, Sheth G, Novak P, Fuchs L, Watts GS, Futscher BW, Mineyev N, Zhu W, LeBeau L, Nagle R, Cranmer L. Abstract 1200: Characterization of a novel radiation-induced sarcoma cell line Cancer Research. 74: 1200-1200. DOI: 10.1158/1538-7445.Am2014-1200 |
0.384 |
|
| 2013 |
Cyr AR, Brown KE, McCormick ML, Coleman MC, Case AJ, Watts GS, Futscher BW, Spitz DR, Domann FE. Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes. Redox Biology. 1: 172-7. PMID 24024150 DOI: 10.1016/J.Redox.2013.01.001 |
0.312 |
|
| 2013 |
Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher BW. Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation. Epigenetics. 8: 1080-8. PMID 23974009 DOI: 10.4161/Epi.25926 |
0.796 |
|
| 2013 |
Zhao F, Severson P, Pacheco S, Futscher BW, Klimecki WT. Arsenic exposure induces the Warburg effect in cultured human cells. Toxicology and Applied Pharmacology. 271: 72-7. PMID 23648393 DOI: 10.1016/J.Taap.2013.04.020 |
0.734 |
|
| 2013 |
Nokes BT, Cunliffe HE, Lafleur B, Mount DW, Livingston RB, Futscher BW, Lang JE. In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene. Journal of Cancer. 4: 104-16. PMID 23386909 DOI: 10.1200/Jco.2011.29.27_Suppl.196 |
0.389 |
|
| 2013 |
Vrba L, Muñoz-Rodríguez JL, Stampfer MR, Futscher BW. miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer. Plos One. 8: e54398. PMID 23342147 DOI: 10.1371/Journal.Pone.0054398 |
0.44 |
|
| 2013 |
Futscher BW. Epigenetic changes during cell transformation. Advances in Experimental Medicine and Biology. 754: 179-94. PMID 22956502 DOI: 10.1007/978-1-4419-9967-2_9 |
0.465 |
|
| 2013 |
Stampfer M, Vrba L, Fuchs L, Brothman A, LaBarge M, Futscher B, Garbe J. Abstract B008: Efficient immortalization of normal human mammary epithelial cells using two pathologically relevant agents does not require gross genomic alterations Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B008 |
0.386 |
|
| 2013 |
Rheinheimer B, Vrba L, Futscher B, Heimark RL. Abstract B13: Epigenetic silencing alters the SLIT2/ROBO1/miR-218-1 signaling axis in pancreatic cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B13 |
0.48 |
|
| 2012 |
Novak P, Stampfer MR, Munoz-Rodriguez JL, Garbe JC, Ehrich M, Futscher BW, Jensen TJ. Cell-type specific DNA methylation patterns define human breast cellular identity. Plos One. 7: e52299. PMID 23284978 DOI: 10.1371/Journal.Pone.0052299 |
0.532 |
|
| 2012 |
Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher BW. Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation. Epigenetics. 7: 1238-48. PMID 22976526 DOI: 10.4161/Epi.22163 |
0.79 |
|
| 2012 |
Teoh-Fitzgerald ML, Fitzgerald MP, Jensen TJ, Futscher BW, Domann FE. Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis. Molecular Cancer Research : McR. 10: 40-51. PMID 22064654 DOI: 10.1158/1541-7786.Mcr-11-0501 |
0.393 |
|
| 2012 |
Severson PL, Tokar EJ, Vrba L, Waalkes MP, Futscher BW. Abstract 5448: Common targets of epigenetic dysfunction in distinct target tissues of arsenic and cadmium induced malignant transformation Cancer Research. 72: 5448-5448. DOI: 10.1158/1538-7445.Am2012-5448 |
0.791 |
|
| 2012 |
Vrba L, Muñoz-Rodríguez JL, Stampfer MR, Futscher BW. Abstract 123: DNA methylation of miRNA promoters in breast cancer Cancer Research. 72: 123-123. DOI: 10.1158/1538-7445.Am2012-123 |
0.473 |
|
| 2012 |
Munoz-Rodriguez JL, Vrba L, Thompson-Carino PA, Martinez ME, Futscher BW. Abstract B34: Pregnancy-associated breast cancer and differentially expressed microRNAs. Cancer Epidemiology, Biomarkers & Prevention. 21. DOI: 10.1158/1055-9965.Disp12-B34 |
0.367 |
|
| 2011 |
Vrba L, Garbe JC, Stampfer MR, Futscher BW. Epigenetic regulation of normal human mammary cell type-specific miRNAs. Genome Research. 21: 2026-37. PMID 21873453 DOI: 10.1101/Gr.123935.111 |
0.394 |
|
| 2011 |
Radhakrishnan VM, Jensen TJ, Cui H, Futscher BW, Martinez JD. Hypomethylation of the 14-3-3σ promoter leads to increased expression in non-small cell lung cancer. Genes, Chromosomes & Cancer. 50: 830-6. PMID 21755566 DOI: 10.1002/Gcc.20904 |
0.459 |
|
| 2011 |
States JC, Barchowsky A, Cartwright IL, Reichard JF, Futscher BW, Lantz RC. Arsenic toxicology: translating between experimental models and human pathology. Environmental Health Perspectives. 119: 1356-63. PMID 21684831 DOI: 10.1289/Ehp.1103441 |
0.343 |
|
| 2011 |
Garbe JC, Vrba L, Jackson MW, Futscher B, LaBarge M, Stampfer MR. Abstract A41: Vulnerability of human mammary epithelial cells to oncogenic transformation Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A41 |
0.3 |
|
| 2010 |
Wnek SM, Jensen TJ, Severson PL, Futscher BW, Gandolfi AJ. Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12 weeks of low-level exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 116: 44-57. PMID 20375083 DOI: 10.1093/Toxsci/Kfq106 |
0.738 |
|
| 2010 |
Vrba L, Jensen TJ, Garbe JC, Heimark RL, Cress AE, Dickinson S, Stampfer MR, Futscher BW. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. Plos One. 5: e8697. PMID 20084174 DOI: 10.1371/Journal.Pone.0008697 |
0.335 |
|
| 2009 |
Jensen TJ, Novak P, Wnek SM, Gandolfi AJ, Futscher BW. Arsenicals produce stable progressive changes in DNA methylation patterns that are linked to malignant transformation of immortalized urothelial cells. Toxicology and Applied Pharmacology. 241: 221-9. PMID 19716837 DOI: 10.1016/J.Taap.2009.08.019 |
0.505 |
|
| 2009 |
Novak P, Jensen TJ, Garbe JC, Stampfer MR, Futscher BW. Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization. Cancer Research. 69: 5251-8. PMID 19509227 DOI: 10.1158/0008-5472.Can-08-4977 |
0.512 |
|
| 2009 |
Jensen TJ, Wozniak RJ, Eblin KE, Wnek SM, Gandolfi AJ, Futscher BW. Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation. Toxicology and Applied Pharmacology. 235: 39-46. PMID 19061910 DOI: 10.1016/J.Taap.2008.10.013 |
0.808 |
|
| 2009 |
Eblin KE, Jensen TJ, Wnek SM, Buffington SE, Futscher BW, Gandolfi AJ. Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling. Toxicology. 255: 107-14. PMID 19014992 DOI: 10.1016/J.Tox.2008.10.007 |
0.337 |
|
| 2008 |
Novak P, Jensen T, Oshiro MM, Watts GS, Kim CJ, Futscher BW. Agglomerative epigenetic aberrations are a common event in human breast cancer. Cancer Research. 68: 8616-25. PMID 18922938 DOI: 10.1158/0008-5472.Can-08-1419 |
0.794 |
|
| 2008 |
Vrba L, Junk DJ, Novak P, Futscher BW. p53 induces distinct epigenetic states at its direct target promoters. Bmc Genomics. 9: 486. PMID 18922183 DOI: 10.1186/1471-2164-9-486 |
0.791 |
|
| 2008 |
Watts GS, Futscher BW, Holtan N, Degeest K, Domann FE, Rose SL. DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. Bmc Medical Genomics. 1: 47. PMID 18826610 DOI: 10.1186/1755-8794-1-47 |
0.498 |
|
| 2008 |
Junk DJ, Vrba L, Watts GS, Oshiro MM, Martinez JD, Futscher BW. Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia (New York, N.Y.). 10: 450-61. PMID 18472962 DOI: 10.1593/Neo.08120 |
0.8 |
|
| 2008 |
Jensen TJ, Novak P, Eblin KE, Gandolfi AJ, Futscher BW. Epigenetic remodeling during arsenical-induced malignant transformation. Carcinogenesis. 29: 1500-8. PMID 18448484 DOI: 10.1093/Carcin/Bgn102 |
0.479 |
|
| 2007 |
Beltran A, Parikh S, Liu Y, Cuevas BD, Johnson GL, Futscher BW, Blancafort P. Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors. Oncogene. 26: 2791-8. PMID 17057734 DOI: 10.1038/Sj.Onc.1210072 |
0.432 |
|
| 2007 |
Wozniak RJ, Klimecki WT, Lau SS, Feinstein Y, Futscher BW. 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. Oncogene. 26: 77-90. PMID 16799634 DOI: 10.1038/Sj.Onc.1209763 |
0.825 |
|
| 2006 |
Ignatenko NA, Yerushalmi HF, Watts GS, Futscher BW, Stringer DE, Marton LJ, Gerner EW. Pharmacogenomics of the polyamine analog 3,8,13,18-tetraaza-10,11-[(E)-1,2-cyclopropyl]eicosane tetrahydrochloride, CGC-11093, in the colon adenocarcinoma cell line HCT1161. Technology in Cancer Research & Treatment. 5: 553-64. PMID 17121431 DOI: 10.1177/153303460600500602 |
0.516 |
|
| 2006 |
Novak P, Jensen T, Oshiro MM, Wozniak RJ, Nouzova M, Watts GS, Klimecki WT, Kim C, Futscher BW. Epigenetic inactivation of the HOXA gene cluster in breast cancer. Cancer Research. 66: 10664-70. PMID 17090521 DOI: 10.1158/0008-5472.Can-06-2761 |
0.815 |
|
| 2006 |
Pike BL, Groshen S, Hsu YH, Shai RM, Wang X, Holtan N, Futscher BW, Hacia JG. Comparisons of PCR-based genome amplification systems using CpG island microarrays. Human Mutation. 27: 589-96. PMID 16652338 DOI: 10.1002/Humu.20329 |
0.34 |
|
| 2006 |
Li H, Watts GS, Oshiro MM, Futscher BW, Domann FE. AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells. Oncogene. 25: 5405-15. PMID 16636674 DOI: 10.1038/Sj.Onc.1209534 |
0.76 |
|
| 2006 |
Rose SL, Fitzgerald MP, White NO, Hitchler MJ, Futscher BW, De Geest K, Domann FE. Epigenetic regulation of maspin expression in human ovarian carcinoma cells. Gynecologic Oncology. 102: 319-24. PMID 16457875 DOI: 10.1016/J.Ygyno.2005.12.025 |
0.438 |
|
| 2005 |
Oshiro MM, Futscher BW, Lisberg A, Wozniak RJ, Klimecki WT, Domann FE, Cress AE. Epigenetic regulation of the cell type-specific gene 14-3-3sigma. Neoplasia (New York, N.Y.). 7: 799-808. PMID 16229802 DOI: 10.1593/Neo.05274 |
0.828 |
|
| 2005 |
Oshiro MM, Kim CJ, Wozniak RJ, Junk DJ, Muñoz-Rodríguez JL, Burr JA, Fitzgerald M, Pawar SC, Cress AE, Domann FE, Futscher BW. Epigenetic silencing of DSC3 is a common event in human breast cancer. Breast Cancer Research : Bcr. 7: R669-80. PMID 16168112 DOI: 10.1186/Bcr1273 |
0.78 |
|
| 2004 |
Nouzova M, Holtan N, Oshiro MM, Isett RB, Munoz-Rodriguez JL, List AF, Narro ML, Miller SJ, Merchant NC, Futscher BW. Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays. The Journal of Pharmacology and Experimental Therapeutics. 311: 968-81. PMID 15302897 DOI: 10.1124/Jpet.104.072488 |
0.81 |
|
| 2004 |
Futscher BW, O'Meara MM, Kim CJ, Rennels MA, Lu D, Gruman LM, Seftor RE, Hendrix MJ, Domann FE. Aberrant methylation of the maspin promoter is an early event in human breast cancer. Neoplasia (New York, N.Y.). 6: 380-9. PMID 15256060 DOI: 10.1593/Neo.04115 |
0.534 |
|
| 2004 |
Domann FE, Futscher BW. Flipping the epigenetic switch. The American Journal of Pathology. 164: 1883-6. PMID 15161624 DOI: 10.1016/S0002-9440(10)63748-0 |
0.564 |
|
| 2004 |
Watts GS, Oshiro MM, Junk DJ, Wozniak RJ, Watterson S, Domann FE, Futscher BW. The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells. Neoplasia (New York, N.Y.). 6: 187-94. PMID 15153330 DOI: 10.1593/Neo.3292 |
0.774 |
|
| 2003 |
Fitzgerald M, Oshiro M, Holtan N, Krager K, Cullen JJ, Futscher BW, Domann FE. Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. Neoplasia (New York, N.Y.). 5: 427-36. PMID 14670180 DOI: 10.1016/S1476-5586(03)80045-3 |
0.785 |
|
| 2003 |
Duan H, Zhang HJ, Yang JQ, Oberley LW, Futscher BW, Domann FE. MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells. Antioxidants & Redox Signaling. 5: 677-88. PMID 14580325 DOI: 10.1089/152308603770310356 |
0.504 |
|
| 2003 |
Oshiro MM, Watts GS, Wozniak RJ, Junk DJ, Munoz-Rodriguez JL, Domann FE, Futscher BW. Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. Oncogene. 22: 3624-34. PMID 12789271 DOI: 10.1038/Sj.Onc.1206545 |
0.812 |
|
| 2002 |
Crowley-Weber CL, Payne CM, Gleason-Guzman M, Watts GS, Futscher B, Waltmire CN, Crowley C, Dvorakova K, Bernstein C, Craven M, Garewal H, Bernstein H. Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. Carcinogenesis. 23: 2063-80. PMID 12507930 DOI: 10.1093/Carcin/23.12.2063 |
0.364 |
|
| 2002 |
Futscher BW, Oshiro MM, Wozniak RJ, Holtan N, Hanigan CL, Duan H, Domann FE. Role for DNA methylation in the control of cell type specific maspin expression. Nature Genetics. 31: 175-9. PMID 12021783 DOI: 10.1038/Ng886 |
0.823 |
|
| 2002 |
Efferth T, Futscher BW, Osieka R. 5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs. Blood Cells, Molecules & Diseases. 27: 637-48. PMID 11482878 DOI: 10.1006/Bcmd.2001.0427 |
0.381 |
|
| 2001 |
Watts G, Tye D, Gleason-Guzman M, Futscher B. Microarray analysis of a human multiple myeloma cell line selected with melphalan or doxorubicin identifies a set of commonly affected genes Nature Genetics. 27: 94-95. DOI: 10.1038/87356 |
0.389 |
|
| 2000 |
Rice JC, Ozcelik H, Maxeiner P, Andrulis I, Futscher BW. Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens Carcinogenesis. 21: 1761-1765. PMID 10964110 DOI: 10.1093/Carcin/21.9.1761 |
0.472 |
|
| 2000 |
Rice JC, Futscher BW. Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter Nucleic Acids Research. 28: 3233-3239. PMID 10954590 DOI: 10.1093/Nar/28.17.3233 |
0.546 |
|
| 2000 |
Domann FE, Rice JC, Hendrix MJC, Futscher BW. Epigenetic silencing of maspin gene expression in human breast cancers International Journal of Cancer. 85: 805-810. PMID 10709100 DOI: 10.1002/(Sici)1097-0215(20000315)85:6<805::Aid-Ijc12>3.0.Co;2-5 |
0.584 |
|
| 1999 |
Watts G, Futscher B, Guzman M, Epner E, Kunkel M, Salmon S. Gene expression profiles associated with MDR1 expression in a doxorubicin-resistant human multiple myeloma cell line Nature Genetics. 23: 45-45. DOI: 10.1038/14306 |
0.388 |
|
| 1998 |
Dodge JE, List AF, Futscher BW. Selective variegated methylation of the p15 CpG island in acute myeloid leukemia. International Journal of Cancer. Journal International Du Cancer. 78: 561-7. PMID 9808523 DOI: 10.1002/(Sici)1097-0215(19981123)78:5<561::Aid-Ijc6>3.0.Co;2-R |
0.804 |
|
| 1998 |
Rice JC, Massey-Brown KS, Futscher BW. Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells Oncogene. 17: 1807-1812. PMID 9778046 DOI: 10.1038/Sj.Onc.1202086 |
0.473 |
|
| 1997 |
Watts GS, Pieper RO, Costello JF, Peng YM, Dalton WS, Futscher BW. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Molecular and Cellular Biology. 17: 5612-9. PMID 9271436 DOI: 10.1128/Mcb.17.9.5612 |
0.486 |
|
| 1997 |
Wang H, Jiang Zg, Wong YW, Dalton WS, Futscher BW, Chan VT. Decreased CP-1 (NF-Y) activity results in transcriptional down-regulation of topoisomerase IIalpha in a doxorubicin-resistant variant of human multiple myeloma RPMI 8226. Biochemical and Biophysical Research Communications. 237: 217-24. PMID 9268689 DOI: 10.1006/Bbrc.1997.7115 |
0.332 |
|
| 1996 |
Pieper RO, Patel S, Ting SA, Futscher BW, Costello JF. Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene Journal of Biological Chemistry. 271: 13916-13924. PMID 8662860 DOI: 10.1074/Jbc.271.23.13916 |
0.464 |
|
| 1996 |
Futscher BW, Foley NE, Gleason-Guzman MC, Meltzer PS, Sullivan DM, Dalton WS. Verapamil suppresses the emergence of P-glycoprotein-mediated multi-drug resistance. International Journal of Cancer. Journal International Du Cancer. 66: 520-5. PMID 8635868 DOI: 10.1002/(Sici)1097-0215(19960516)66:4<520::Aid-Ijc16>3.0.Co;2-B |
0.316 |
|
| 1996 |
Watts GS, Futscher BW. Detecting differences in 5-methylcytosine using restriction enzyme isoschizomers: an endogenous control for complete digestion. Nucleic Acids Research. 23: 4740-1. PMID 8524671 DOI: 10.1093/Nar/23.22.4740 |
0.341 |
|
| 1994 |
Futscher BW, Abbaszadegan MR, Domann F, Dalton WS. Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells. Biochemical Pharmacology. 47: 1601-6. PMID 8185674 DOI: 10.1016/0006-2952(94)90538-X |
0.342 |
|
| 1994 |
Costello JF, Futscher BW, Kroes RA, Pieper RO. Methylation-related chromatin structure is associated with exclusion of transcription factors from and suppressed expression of the O-6-methylguanine DNA methyltransferase gene in human glioma cell lines Molecular and Cellular Biology. 14: 6515-6521. PMID 7523853 DOI: 10.1128/Mcb.14.10.6515 |
0.52 |
|
| 1994 |
Klimecki WT, Futscher BW, Grogan TM, Dalton WS. P-glycoprotein expression and function in circulating blood cells from normal volunteers. Blood. 83: 2451-8. PMID 7513198 DOI: 10.1182/Blood.V83.9.2451.2451 |
0.34 |
|
| 1992 |
Grabowski DT, Pieper RO, Futscher BW, Deutsch WA, Erickson LC, Kelley MR. Expression of ribosomal phosphoprotein PO is induced by antitumor agents and increased in Mer- human tumor cell lines. Carcinogenesis. 13: 259-63. PMID 1740017 DOI: 10.1093/Carcin/13.2.259 |
0.338 |
|
| 1992 |
Futscher BW, Pieper RO, Barnes DM, Hanin I, Erickson LC. DNA-damaging and transcription-terminating lesions induced by AF64A in vitro. Journal of Neurochemistry. 58: 1504-9. PMID 1548483 DOI: 10.1111/J.1471-4159.1992.Tb11371.X |
0.348 |
|
| 1992 |
Micetich KC, Futscher B, Koch D, Fisher RI, Erickson LC. Phase I study of streptozocin- and carmustine-sequenced administration in patients with advanced cancer. Journal of the National Cancer Institute. 84: 256-60. PMID 1531148 DOI: 10.1093/Jnci/84.4.256 |
0.317 |
|
| 1992 |
Nelson MA, Futscher BW, Loew MR, Tim Bowden G. Analysis of the Harvey ras gene in cisplatin-initiated mouse skin tumors by polymerase chain reaction and direct DNA sequencing Cancer Letters. 65: 27-33. PMID 1511406 DOI: 10.1016/0304-3835(92)90209-E |
0.351 |
|
| 1992 |
Nelson MA, Futscher BW, Kinsella T, Wymer J, Bowden GT. Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors. Proceedings of the National Academy of Sciences of the United States of America. 89: 6398-402. PMID 1352887 DOI: 10.1073/Pnas.89.14.6398 |
0.316 |
|
| 1991 |
Pieper RO, Costello JF, Kroes RA, Futscher BW, Marathi U, Erickson LC. Direct correlation between methylation status and expression of the human O-6-methylguanine DNA methyltransferase gene. Cancer Communications. 3: 241-53. PMID 1716139 DOI: 10.3727/095535491820873092 |
0.52 |
|
| 1990 |
Pieper RO, Futscher BW, Dong Q, Ellis TM, Erickson LC. Comparison of O-6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction technique. Cancer Communications. 2: 13-20. PMID 2369549 DOI: 10.3727/095535490820874812 |
0.393 |
|
| 1990 |
Vlahos NS, Futscher BW, Hora NK, Trent JM, Erickson LC. Gene amplification affecting O(6)-alkylguanine-DNA alkyltransferase activity is not detected in nitrosourea resistant or sensitive human cell lines. Carcinogenesis. 11: 479-83. PMID 2311191 DOI: 10.1093/Carcin/11.3.479 |
0.448 |
|
| 1989 |
Pieper RO, Futscher BW, Erickson LC. Transcription-terminating lesions induced by bifunctional alkylating agents in vitro. Carcinogenesis. 10: 1307-14. PMID 2736721 DOI: 10.1093/Carcin/10.7.1307 |
0.338 |
|
| 1989 |
Futscher BW, Micetich KC, Barnes DM, Fisher RI, Erickson LC. Inhibition of a specific DNA repair system and nitrosourea cytotoxicity in resistant human cancer cells. Cancer Communications. 1: 65-73. PMID 2534817 DOI: 10.3727/095535489820875444 |
0.403 |
|
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