| Year |
Citation |
Score |
| 2018 |
Zhu X, Yuan C, Tian C, Li C, Nie F, Song X, Zeng R, Wu D, Hao X, Li L. The plant sesquiterpene lactone parthenoide inhibits Wnt/β-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1. The Journal of Biological Chemistry. PMID 29462785 DOI: 10.1074/jbc.M117.819300 |
0.319 |
|
| 2015 |
Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A. Gnb isoforms orchestrate a signaling pathway comprising Rac1 and Plcβ2/3 leading to LFA-1 activation and neutrophil arrest in vivo. Blood. PMID 26468229 DOI: 10.1182/Blood-2015-06-651034 |
0.392 |
|
| 2014 |
Koraishy FM, Silva C, Mason S, Wu D, Cantley LG. Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling. The Journal of Biological Chemistry. 289: 14341-50. PMID 24692544 DOI: 10.1074/Jbc.M114.563213 |
0.332 |
|
| 2013 |
Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D. Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation. The Journal of Biological Chemistry. 288: 33978-84. PMID 24114843 DOI: 10.1074/Jbc.M113.477406 |
0.376 |
|
| 2012 |
Gan X, Wang J, Wang C, Sommer E, Kozasa T, Srinivasula S, Alessi D, Offermanns S, Simon MI, Wu D. PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. Nature Cell Biology. 14: 686-96. PMID 22609986 DOI: 10.1038/Ncb2507 |
0.313 |
|
| 2012 |
Bao J, Zheng JJ, Wu D. The structural basis of DKK-mediated inhibition of Wnt/LRP signaling. Science Signaling. 5: pe22. PMID 22589387 DOI: 10.1126/scisignal.2003028 |
0.32 |
|
| 2011 |
Xiao W, Kashiwakura J, Hong H, Yasudo H, Ando T, Maeda-Yamamoto M, Wu D, Kawakami Y, Kawakami T. Phospholipase C-β3 regulates FcɛRI-mediated mast cell activation by recruiting the protein phosphatase SHP-1. Immunity. 34: 893-904. PMID 21683628 DOI: 10.1016/j.immuni.2011.04.010 |
0.362 |
|
| 2010 |
Lee HJ, Finkelstein D, Li X, Wu D, Shi DL, Zheng JJ. Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein. The Journal of Biological Chemistry. 285: 41549-56. PMID 21044957 DOI: 10.1074/Jbc.M110.193383 |
0.443 |
|
| 2010 |
Wu D, Pan W. GSK3: a multifaceted kinase in Wnt signaling. Trends in Biochemical Sciences. 35: 161-8. PMID 19884009 DOI: 10.1016/j.tibs.2009.10.002 |
0.356 |
|
| 2009 |
Qin Y, Li L, Pan W, Wu D. Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. The Journal of Biological Chemistry. 284: 22544-8. PMID 19561074 DOI: 10.1074/Jbc.M109.014399 |
0.422 |
|
| 2008 |
Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L, Lucast L, Khoo C, Zhang X, Li L, Abrams CS, Sokol SY, Wu D. Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science (New York, N.Y.). 321: 1350-3. PMID 18772438 DOI: 10.1126/Science.1160741 |
0.337 |
|
| 2008 |
Chen L, Wang K, Shao Y, Huang J, Li X, Shan J, Wu D, Zheng JJ. Structural insight into the mechanisms of Wnt signaling antagonism by Dkk. The Journal of Biological Chemistry. 283: 23364-70. PMID 18524778 DOI: 10.1074/Jbc.M802375200 |
0.401 |
|
| 2008 |
Wang K, Zhang Y, Li X, Chen L, Wang H, Wu J, Zheng J, Wu D. Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. The Journal of Biological Chemistry. 283: 23371-5. PMID 18502762 DOI: 10.1074/Jbc.M802376200 |
0.406 |
|
| 2007 |
Tang LY, Deng N, Wang LS, Dai J, Wang ZL, Jiang XS, Li SJ, Li L, Sheng QH, Wu DQ, Li L, Zeng R. Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction. Molecular & Cellular Proteomics : McP. 6: 1952-67. PMID 17693683 DOI: 10.1074/mcp.M700120-MCP200 |
0.309 |
|
| 2007 |
Nomura S, Fukaya M, Tsujioka T, Wu D, Watanabe M. Phospholipase Cbeta3 is distributed in both somatodendritic and axonal compartments and localized around perisynapse and smooth endoplasmic reticulum in mouse Purkinje cell subsets. The European Journal of Neuroscience. 25: 659-72. PMID 17298601 DOI: 10.1111/J.1460-9568.2007.05334.X |
0.375 |
|
| 2007 |
Zhao T, Nalbant P, Hoshino M, Dong X, Wu D, Bokoch GM. Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function. Journal of Leukocyte Biology. 81: 1127-36. PMID 17227822 DOI: 10.1189/jlb.0406251 |
0.315 |
|
| 2006 |
Bonacci TM, Mathews JL, Yuan C, Lehmann DM, Malik S, Wu D, Font JL, Bidlack JM, Smrcka AV. Differential targeting of Gbetagamma-subunit signaling with small molecules. Science (New York, N.Y.). 312: 443-6. PMID 16627746 DOI: 10.1126/Science.1120378 |
0.378 |
|
| 2005 |
Dong X, Mo Z, Bokoch G, Guo C, Li Z, Wu D. P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils Current Biology. 15: 1874-1879. PMID 16243036 DOI: 10.1016/J.Cub.2005.09.014 |
0.35 |
|
| 2005 |
Maejima T, Oka S, Hashimotodani Y, Ohno-Shosaku T, Aiba A, Wu D, Waku K, Sugiura T, Kano M. Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6826-35. PMID 16033892 DOI: 10.1523/Jneurosci.0945-05.2005 |
0.308 |
|
| 2005 |
Li Z, Dong X, Dong X, Wang Z, Liu W, Deng N, Ding Y, Tang L, Hla T, Zeng R, Li L, Wu D. Regulation of PTEN by Rho small GTPases. Nature Cell Biology. 7: 399-404. PMID 15793569 DOI: 10.1038/Ncb1236 |
0.399 |
|
| 2005 |
Li X, Zhang Y, Kang H, Liu W, Liu P, Zhang J, Harris SE, Wu D. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. The Journal of Biological Chemistry. 280: 19883-7. PMID 15778503 DOI: 10.1074/Jbc.M413274200 |
0.3 |
|
| 2005 |
Sanchez T, Thangada S, Wu MT, Kontos CD, Wu D, Wu H, Hla T. PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proceedings of the National Academy of Sciences of the United States of America. 102: 4312-7. PMID 15764699 DOI: 10.1073/Pnas.0409784102 |
0.432 |
|
| 2004 |
Pan WJ, Pang SZ, Huang T, Guo HY, Wu D, Li L. Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1. Cell Research. 14: 324-30. PMID 15353129 DOI: 10.1038/Sj.Cr.7290232 |
0.383 |
|
| 2004 |
Maye P, Zheng J, Li L, Wu D. Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway. The Journal of Biological Chemistry. 279: 24659-65. PMID 15067007 DOI: 10.1074/Jbc.M311724200 |
0.447 |
|
| 2003 |
Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Molecular Cell. 12: 1251-60. PMID 14636582 DOI: 10.1016/S1097-2765(03)00427-1 |
0.382 |
|
| 2003 |
Weaver C, Farr GH, Pan W, Rowning BA, Wang J, Mao J, Wu D, Li L, Larabell CA, Kimelman D. GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs. Development (Cambridge, England). 130: 5425-36. PMID 14507779 DOI: 10.1242/Dev.00737 |
0.379 |
|
| 2003 |
Li Z, Hannigan M, Mo Z, Liu B, Lu W, Wu Y, Smrcka AV, Wu G, Li L, Liu M, Huang CK, Wu D. Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell. 114: 215-27. PMID 12887923 DOI: 10.1016/S0092-8674(03)00559-2 |
0.444 |
|
| 2002 |
Mao J, Maye P, Kogerman P, Tejedor FJ, Toftgard R, Xie W, Wu G, Wu D. Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. The Journal of Biological Chemistry. 277: 35156-61. PMID 12138125 DOI: 10.1074/Jbc.M206743200 |
0.313 |
|
| 2002 |
Hannigan M, Zhan L, Li Z, Ai Y, Wu D, Huang CK. Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proceedings of the National Academy of Sciences of the United States of America. 99: 3603-8. PMID 11904423 DOI: 10.1073/Pnas.052010699 |
0.316 |
|
| 2002 |
Li L, Mao J, Sun L, Liu W, Wu D. Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. The Journal of Biological Chemistry. 277: 5977-81. PMID 11742004 DOI: 10.1074/Jbc.M111131200 |
0.357 |
|
| 2002 |
Mao J, Wu D. Functional interaction of G alpha 13 with p115RhoGEF determined with transcriptional reporter system. Methods in Enzymology. 345: 404-10. PMID 11665624 DOI: 10.1016/S0076-6879(02)45033-1 |
0.427 |
|
| 2001 |
Miyata M, Kim HT, Hashimoto K, Lee TK, Cho SY, Jiang H, Wu Y, Jun K, Wu D, Kano M, Shin HS. Deficient long-term synaptic depression in the rostral cerebellum correlated with impaired motor learning in phospholipase C β4 mutant mice European Journal of Neuroscience. 13: 1945-1954. PMID 11403688 DOI: 10.1046/J.0953-816X.2001.01570.X |
0.329 |
|
| 2001 |
Yang M, Sang H, Rahman A, Wu D, Malik AB, Ye RD. G alpha 16 couples chemoattractant receptors to NF-kappa B activation. Journal of Immunology (Baltimore, Md. : 1950). 166: 6885-92. PMID 11359849 DOI: 10.4049/Jimmunol.166.11.6885 |
0.311 |
|
| 2000 |
Wong HC, Mao J, Nguyen JT, Srinivas S, Zhang W, Liu B, Li L, Wu D, Zheng J. Structural basis of the recognition of the Dishevelled DEP domain in the Wnt signaling pathway Nature Structural Biology. 7: 1178-1184. PMID 11101902 DOI: 10.1038/82047 |
0.414 |
|
| 2000 |
Hashimoto K, Watanabe M, Kurihara H, Offermanns S, Jiang H, Wu Y, Jun K, Shin HS, Inoue Y, Wu D, Simon MI, Kano M. Climbing fiber synapse elimination during postnatal cerebellar development requires signal transduction involving G alpha q and phospholipase C beta 4. Progress in Brain Research. 124: 31-48. PMID 10943115 DOI: 10.1016/S0079-6123(00)24006-5 |
0.351 |
|
| 2000 |
Li Z, Jiang H, Xie W, Zhang Z, Smrcka AV, Wu D. Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science (New York, N.Y.). 287: 1046-9. PMID 10669417 DOI: 10.1126/Science.287.5455.1046 |
0.415 |
|
| 2000 |
Strovel ET, Wu D, Sussman DJ. Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription. Journal of Biological Chemistry. 275: 2399-2403. PMID 10644691 DOI: 10.1074/Jbc.275.4.2399 |
0.42 |
|
| 1999 |
Yuan H, Mao J, Li L, Wu D. Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation. The Journal of Biological Chemistry. 274: 30419-23. PMID 10521419 DOI: 10.1074/Jbc.274.43.30419 |
0.43 |
|
| 1999 |
Xie W, Samoriski GM, McLaughlin JP, Romoser VA, Smrcka A, Hinkle PM, Bidlack JM, Gross RA, Jiang H, Wu D. Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids. Proceedings of the National Academy of Sciences of the United States of America. 96: 10385-90. PMID 10468617 DOI: 10.1073/Pnas.96.18.10385 |
0.335 |
|
| 1999 |
Li L, Yuan H, Weaver CD, Mao J, Farr GH, Sussman DJ, Jonkers J, Kimelman D, Wu D. Axin and Frat1 interact with Dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1 Embo Journal. 18: 4233-4240. PMID 10428961 DOI: 10.1093/Emboj/18.15.4233 |
0.447 |
|
| 1999 |
Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, Wu D. Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. The Journal of Biological Chemistry. 274: 129-34. PMID 9867820 DOI: 10.1074/Jbc.274.1.129 |
0.504 |
|
| 1998 |
Kano M, Hashimoto K, Watanabe M, Kurihara H, Offermanns S, Jiang H, Wu Y, Jun K, Shin HS, Inoue Y, Simon MI, Wu D. Phospholipase cbeta4 is specifically involved in climbing fiber synapse elimination in the developing cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 95: 15724-9. PMID 9861037 DOI: 10.1073/Pnas.95.26.15724 |
0.336 |
|
| 1998 |
Mao J, Yuan H, Xie W, Wu D. Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13. Proceedings of the National Academy of Sciences of the United States of America. 95: 12973-6. PMID 9789025 DOI: 10.1073/Pnas.95.22.12973 |
0.438 |
|
| 1998 |
Mao J, Xie W, Yuan H, Simon MI, Mano H, Wu D. Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13. The Embo Journal. 17: 5638-46. PMID 9755164 DOI: 10.1093/Emboj/17.19.5638 |
0.433 |
|
| 1998 |
Sankaran B, Osterhout J, Wu D, Smrcka AV. Identification of a structural element in phospholipase C beta2 that interacts with G protein betagamma subunits. The Journal of Biological Chemistry. 273: 7148-54. PMID 9507029 DOI: 10.1074/Jbc.273.12.7148 |
0.343 |
|
| 1997 |
Xie W, Jiang H, Wu Y, Wu D. Two Basic Amino Acids in the Second Inner Loop of the Interleukin-8 Receptor Are Essential for Gα16 Coupling Journal of Biological Chemistry. 272: 24948-24951. PMID 9312098 DOI: 10.1074/Jbc.272.40.24948 |
0.309 |
|
| 1997 |
Jiang H, Kuang Y, Wu Y, Xie W, Simon MI, Wu D. Roles of phospholipase C beta2 in chemoattractant-elicited responses. Proceedings of the National Academy of Sciences of the United States of America. 94: 7971-5. PMID 9223297 DOI: 10.1073/Pnas.94.15.7971 |
0.345 |
|
| 1996 |
Jiang H, Lyubarsky A, Dodd R, Vardi N, Pugh E, Baylor D, Simon MI, Wu D. Phospholipase C beta 4 is involved in modulating the visual response in mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 14598-601. PMID 8962098 DOI: 10.1073/Pnas.93.25.14598 |
0.351 |
|
| 1996 |
Jiang H, Kuang Y, Wu Y, Smrcka A, Simon MI, Wu D. Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors. The Journal of Biological Chemistry. 271: 13430-4. PMID 8662841 DOI: 10.1074/Jbc.271.23.13430 |
0.407 |
|
| 1996 |
Kuang Y, Wu Y, Jiang H, Wu D. Selective G protein coupling by C-C chemokine receptors. Journal of Biological Chemistry. 271: 3975-3978. PMID 8626727 DOI: 10.1074/Jbc.271.8.3975 |
0.341 |
|
| 1993 |
Jiang H, Wu D, Simon MI. The transforming activity of activated G alpha 12. Febs Letters. 330: 319-22. PMID 8397105 DOI: 10.1016/0014-5793(93)80896-3 |
0.359 |
|
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