Alyssa H. Hasty - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Physiology Biology, Nutrition, Molecular Biology

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Schleh MW, Ameka M, Rodriguez A, Hasty AH. Deficiency of the hemoglobin-haptoglobin receptor, CD163, worsens insulin sensitivity in obese male mice. Biorxiv : the Preprint Server For Biology. PMID 38895370 DOI: 10.1101/2024.05.31.596887  0.385
2024 Burak MF, Stanley TL, Lawson EA, Campbell SL, Lynch L, Hasty AH, Domingos AI, Dixit VD, Hotamışlıgil GS, Sheedy FJ, Dixon AE, Brinkley TE, Hill JA, Donath MY, Grinspoon SK. Adiposity, immunity, and inflammation: interrelationships in health and disease: A report from 24 annual Harvard nutrition obesity symposium, June 2023. The American Journal of Clinical Nutrition. PMID 38705359 DOI: 10.1016/j.ajcnut.2024.04.029  0.346
2023 Caslin HL, Bolus WR, Thomas C, Toki S, Norlander AE, Peebles RS, Hasty AH. Bovine Serum Albumin Elicits IL-33-Dependent Adipose Tissue Eosinophilia: Potential Relevance to Ovalbumin-induced Models of Allergic Disease. Immunohorizons. 7: 842-852. PMID 38095595 DOI: 10.4049/immunohorizons.2300061  0.332
2023 Schleh MW, Caslin HL, Garcia JN, Mashayekhi M, Srivastava G, Bradley AB, Hasty AH. Metaflammation in obesity and its therapeutic targeting. Science Translational Medicine. 15: eadf9382. PMID 37992150 DOI: 10.1126/scitranslmed.adf9382  0.378
2023 Winn NC, Patel VS, Blair JA, Rodriguez A, Garcia JN, Yang TS, Hasty AH. Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 37610411 DOI: 10.1152/ajpendo.00140.2023  0.435
2023 Sprenkle NT, Winn NC, Bunn KE, Zhao Y, Park DJ, Giese BG, Karijolich JJ, Ansel KM, Serezani CH, Hasty AH, Pua HH. The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue. Cell Reports. 42: 112928. PMID 37542720 DOI: 10.1016/j.celrep.2023.112928  0.38
2023 Clark JM, Garvey WT, Niswender KD, Schmidt AM, Ahima RS, Aleman JO, Battarbee AN, Beckman J, Bennett WL, Brown NJ, Chandler-Laney P, Cox N, Goldberg IJ, Habegger KM, Harper LM, ... Hasty AH, et al. Obesity and Overweight: Probing Causes, Consequences, and Novel Therapeutic Approaches Through the American Heart Association's Strategically Focused Research Network. Journal of the American Heart Association. e8192. PMID 36752232 DOI: 10.1161/JAHA.122.027693  0.306
2023 Caslin HL, Cottam MA, Piñon JM, Boney LY, Hasty AH. Weight cycling induces innate immune memory in adipose tissue macrophages. Frontiers in Immunology. 13: 984859. PMID 36713396 DOI: 10.3389/fimmu.2022.984859  0.318
2022 Winn NC, Wolf EM, Garcia JN, Hasty AH. Exon 2-mediated deletion of Trem2 does not worsen metabolic function in diet-induced obese mice. The Journal of Physiology. PMID 36044273 DOI: 10.1113/JP283684  0.513
2022 Ameka MK, Beavers WN, Shaver CM, Ware LB, Kerchberger VE, Schoenfelt KQ, Sun L, Koyama T, Skaar EP, Becker L, Hasty AH. An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload. International Journal of Molecular Sciences. 23. PMID 35806422 DOI: 10.3390/ijms23137417  0.331
2022 Winn NC, Cottam MA, Bhanot M, Caslin HL, Garcia JN, Arrojo E Drigo R, Hasty AH. Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Diet-Induced Obese Mice. Diabetes. PMID 35802127 DOI: 10.2337/db22-0161  0.373
2022 Cottam MA, Caslin HL, Winn NC, Hasty AH. Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and weight regain in mice. Nature Communications. 13: 2950. PMID 35618862 DOI: 10.1038/s41467-022-30646-4  0.376
2022 Fuseini H, Smith R, Nochowicz CH, Simmons JD, Hannah L, Wanjalla CN, Gabriel CL, Mashayekhi M, Bailin SS, Castilho JL, Hasty AH, Koethe JR, Kalams SA. Leptin Promotes Greater Ki67 Expression in CD4 T Cells From Obese Compared to Lean Persons Living With HIV. Frontiers in Immunology. 12: 796898. PMID 35111163 DOI: 10.3389/fimmu.2021.796898  0.305
2021 Winn NC, Wolf EM, Cottam MA, Bhanot M, Hasty AH. Myeloid specific deletion of ferroportin impairs macrophage bioenergetics but is disconnected from systemic insulin action in adult mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 34338042 DOI: 10.1152/ajpendo.00116.2021  0.307
2021 Winn NC, Cottam MA, Wasserman DH, Hasty AH. Exercise and Adipose Tissue Immunity: Outrunning Inflammation. Obesity (Silver Spring, Md.). 29: 790-801. PMID 33899336 DOI: 10.1002/oby.23147  0.331
2020 Caslin HL, Bhanot M, Bolus WR, Hasty AH. Adipose tissue macrophages: Unique polarization and bioenergetics in obesity. Immunological Reviews. PMID 32237081 DOI: 10.1111/Imr.12853  0.5
2020 Rogers LM, Serezani CH, Eastman AJ, Hasty AH, Englund-Ögge L, Jacobsson B, Vickers KC, Aronoff DM. Palmitate induces apoptotic cell death and inflammasome activation in human placental macrophages. Placenta. 90: 45-51. PMID 32056551 DOI: 10.1016/J.Placenta.2019.12.009  0.375
2019 Breuer DA, Pacheco MC, Washington MK, Montgomery SA, Hasty AH, Kennedy AJ. CD8T CELLS REGULATE LIVER INJURY IN OBESITY-RELATED NONALCOHOLIC FATTY LIVER DISEASE. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31709830 DOI: 10.1152/Ajpgi.00040.2019  0.515
2019 Peterson KR, Gutierrez DA, Kikuchi T, Anderson-Baucum EK, Winn NC, Shuey MM, Bolus WR, McGuinness OP, Hasty AH. Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency. American Journal of Physiology. Endocrinology and Metabolism. PMID 31084499 DOI: 10.1152/Ajpendo.00042.2019  0.455
2019 Caslin HL, Hasty AH. Extrinsic and Intrinsic Immunometabolism Converge: Perspectives on Future Research and Therapeutic Development for Obesity. Current Obesity Reports. PMID 30919312 DOI: 10.1007/S13679-019-00344-2  0.392
2019 May-Zhang LS, Chen Z, Dosoky NS, Yancey PG, Boyd KL, Hasty AH, Linton MF, Davies SS. Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor Mice Improves Indices of Cardiometabolic Disease. Scientific Reports. 9: 420. PMID 30674978 DOI: 10.1038/S41598-018-37373-1  0.55
2018 Bolus WR, Kennedy AJ, Hasty AH. Obesity-induced reduction of adipose eosinophils is reversed with low-calorie dietary intervention. Physiological Reports. 6: e13919. PMID 30488596 DOI: 10.14814/Phy2.13919  0.549
2018 McDonnell WJ, Koethe JR, Mallal SA, Pilkinton MA, Kirabo A, Ameka MK, Cottam MA, Hasty AH, Kennedy AJ. High CD8 T Cell Receptor Clonality and Altered CDR3 Properties are Associated with Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity. Diabetes. PMID 30181158 DOI: 10.2337/Db18-0040  0.489
2018 Bolus WR, Hasty AH. Contributions of Innate Type 2 Inflammation to Adipose Function. Journal of Lipid Research. PMID 29891508 DOI: 10.1194/Jlr.R085993  0.507
2018 Peterson KR, Cottam MA, Kennedy AJ, Hasty AH. Macrophage-Targeted Therapeutics for Metabolic Disease. Trends in Pharmacological Sciences. PMID 29628274 DOI: 10.1016/J.Tips.2018.03.001  0.403
2017 Bolus WR, Peterson KR, Hubler MJ, Kennedy AJ, Gruen ML, Hasty AH. Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments. Molecular Metabolism. PMID 29306658 DOI: 10.1016/J.Molmet.2017.12.004  0.531
2017 Koethe JR, McDonnell W, Kennedy A, Abana CO, Pilkinton M, Setliff I, Georgiev I, Barnett L, Hager CC, Smith R, Kalams SA, Hasty A, Mallal S. Adipose Tissue is Enriched for Activated and Late-differentiated CD8+ T cells, and Shows Distinct CD8+ Receptor Usage, Compared to Blood in HIV-infected Persons. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 29040163 DOI: 10.1097/Qai.0000000000001573  0.33
2017 Peterson KR, Flaherty DK, Hasty AH. Obesity Alters B Cell and Macrophage Populations in Brown Adipose Tissue. Obesity (Silver Spring, Md.). PMID 28922564 DOI: 10.1002/Oby.21982  0.505
2016 Orr JS, Kennedy AJ, Hill AA, Anderson-Baucum EK, Hubler MJ, Hasty AH. CC-chemokine receptor 7 (CCR7) deficiency alters adipose tissue leukocyte populations in mice. Physiological Reports. 4. PMID 27655794 DOI: 10.14814/Phy2.12971  0.562
2016 Ong HH, Webb CD, Gruen ML, Hasty AH, Gore JC, Welch EB. Fat-water MRI of a diet-induced obesity mouse model at 15.2T. Journal of Medical Imaging (Bellingham, Wash.). 3: 026002. PMID 27226976 DOI: 10.1117/1.Jmi.3.2.026002  0.487
2015 Hill AA, Anderson-Baucum EK, Kennedy AJ, Webb CD, Yull FE, Hasty AH. Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment. Molecular Metabolism. 4: 665-77. PMID 26779432 DOI: 10.1016/J.Molmet.2015.07.005  0.529
2015 Wainright KS, Fleming NJ, Rowles JL, Welly RJ, Zidon TM, Park YM, Gaines TL, Scroggins RJ, Anderson-Baucum EK, Hasty AH, Vieira-Potter VJ, Padilla J. Retention of sedentary obese visceral white adipose tissue phenotype with intermittent physical activity despite reduced adiposity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R594-602. PMID 26180183 DOI: 10.1152/Ajpregu.00042.2015  0.432
2015 Bolus WR, Gutierrez DA, Kennedy AJ, Anderson-Baucum EK, Hasty AH. CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue. Journal of Leukocyte Biology. PMID 25934927 DOI: 10.1189/Jlb.3Hi0115-018R  0.533
2015 Hubler MJ, Peterson KR, Hasty AH. Iron homeostasis: a new job for macrophages in adipose tissue? Trends in Endocrinology and Metabolism: Tem. 26: 101-9. PMID 25600948 DOI: 10.1016/J.Tem.2014.12.005  0.385
2015 Ong HH, Webb CD, Gruen ML, Hasty AH, Gore JC, Welch EB. Fat-water MRI is sensitive to local adipose tissue inflammatory changes in a diet-induced obesity mouse model at 15T Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9417. DOI: 10.1117/12.2082333  0.495
2014 Hill AA, Reid Bolus W, Hasty AH. A decade of progress in adipose tissue macrophage biology. Immunological Reviews. 262: 134-52. PMID 25319332 DOI: 10.1111/Imr.12216  0.531
2014 Reddy IA, Wasserman DH, Ayala JE, Hasty AH, Abumrad NN, Galli A. Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery. Acs Chemical Neuroscience. 5: 943-51. PMID 25068716 DOI: 10.1021/Cn500137D  0.482
2014 Buckman LB, Anderson-Baucum EK, Hasty AH, Ellacott KLj. Regulation of S100B in white adipose tissue by obesity in mice. Adipocyte. 3: 215-20. PMID 25068089 DOI: 10.4161/adip.28730  0.456
2014 Anderson-Baucum EK, Major AS, Hasty AH. A possible secondary immune response in adipose tissue during weight cycling: The ups and downs of yo-yo dieting. Adipocyte. 3: 141-5. PMID 24719788 DOI: 10.4161/adip.27556  0.342
2014 Hasty AH, Gutierrez DA. What have we really learned about macrophage recruitment to adipose tissue? Endocrinology. 155: 12-4. PMID 24364586 DOI: 10.1210/En.2013-2027  0.575
2014 Orr JS, Kennedy A, Anderson-Baucum EK, Webb CD, Fordahl SC, Erikson KM, Zhang Y, Etzerodt A, Moestrup SK, Hasty AH. Obesity alters adipose tissue macrophage iron content and tissue iron distribution. Diabetes. 63: 421-32. PMID 24130337 DOI: 10.2337/Db13-0213  0.453
2014 Buckman LB, Hasty AH, Flaherty DK, Buckman CT, Thompson MM, Matlock BK, Weller K, Ellacott KL. Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system. Brain, Behavior, and Immunity. 35: 33-42. PMID 23831150 DOI: 10.1016/J.Bbi.2013.06.007  0.542
2013 Hasty AH, Yvan-Charvet L. Liver X receptor α-dependent iron handling in M2 macrophages: The missing link between cholesterol and intraplaque hemorrhage? Circulation Research. 113: 1182-5. PMID 24201110 DOI: 10.1161/Circresaha.113.302613  0.381
2013 Kennedy A, Webb CD, Hill AA, Gruen ML, Jackson LG, Hasty AH. Loss of CCR5 results in glucose intolerance in diet-induced obese mice. American Journal of Physiology. Endocrinology and Metabolism. 305: E897-906. PMID 23941876 DOI: 10.1152/Ajpendo.00177.2013  0.591
2013 Anderson EK, Gutierrez DA, Kennedy A, Hasty AH. Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance. Diabetes. 62: 3180-8. PMID 23733197 DOI: 10.2337/Db12-1076  0.458
2013 Orr JS, Kennedy AJ, Hasty AH. Isolation of adipose tissue immune cells. Journal of Visualized Experiments : Jove. e50707. PMID 23728515 DOI: 10.3791/50707  0.493
2013 Kang L, Lantier L, Kennedy A, Bonner JS, Mayes WH, Bracy DP, Bookbinder LH, Hasty AH, Thompson CB, Wasserman DH. Hyaluronan accumulates with high-fat feeding and contributes to insulin resistance. Diabetes. 62: 1888-96. PMID 23349492 DOI: 10.2337/Db12-1502  0.372
2012 Orr JS, Puglisi MJ, Ellacott KL, Lumeng CN, Wasserman DH, Hasty AH. Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. Diabetes. 61: 2718-27. PMID 22751700 DOI: 10.2337/Db11-1595  0.559
2012 Anderson EK, Hill AA, Hasty AH. Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1687-95. PMID 22556332 DOI: 10.1161/Atvbaha.112.250142  0.43
2012 Kennedy A, Gruen ML, Gutierrez DA, Surmi BK, Orr JS, Webb CD, Hasty AH. Impact of macrophage inflammatory protein-1α deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion. Plos One. 7: e31508. PMID 22359597 DOI: 10.1371/Journal.Pone.0031508  0.81
2012 Gutierrez DA, Hasty AH. Haematopoietic leptin receptor deficiency does not affect macrophage accumulation in adipose tissue or systemic insulin sensitivity. The Journal of Endocrinology. 212: 343-51. PMID 22194312 DOI: 10.1530/Joe-11-0338  0.572
2011 Gutierrez DA, Kennedy A, Orr JS, Anderson EK, Webb CD, Gerrald WK, Hasty AH. Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity. Diabetes. 60: 2820-9. PMID 21926275 DOI: 10.2337/Db11-0314  0.524
2010 Surmi BK, Webb CD, Ristau AC, Hasty AH. Absence of macrophage inflammatory protein-1{alpha} does not impact macrophage accumulation in adipose tissue of diet-induced obese mice. American Journal of Physiology. Endocrinology and Metabolism. 299: E437-45. PMID 20551286 DOI: 10.1152/Ajpendo.00050.2010  0.821
2010 Anderson EK, Gutierrez DA, Hasty AH. Adipose tissue recruitment of leukocytes. Current Opinion in Lipidology. 21: 172-7. PMID 20410821 DOI: 10.1097/Mol.0B013E3283393867  0.515
2010 Kennedy AJ, Ellacott KL, King VL, Hasty AH. Mouse models of the metabolic syndrome. Disease Models & Mechanisms. 3: 156-66. PMID 20212084 DOI: 10.1242/Dmm.003467  0.451
2010 Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ, Woodcock SR, Franek A, Pekarova M, Khoo NK, Hasty AH, Baldus S, Freeman BA. Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 938-45. PMID 20167658 DOI: 10.1161/Atvbaha.109.201582  0.361
2010 Guri AJ, Misyak SA, Hontecillas R, Hasty A, Liu D, Si H, Bassaganya-Riera J. Abscisic acid ameliorates atherosclerosis by suppressing macrophage and CD4+ T cell recruitment into the aortic wall. The Journal of Nutritional Biochemistry. 21: 1178-85. PMID 20092994 DOI: 10.1016/J.Jnutbio.2009.10.003  0.48
2010 Surmi BK, Hasty AH. The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue. Vascular Pharmacology. 52: 27-36. PMID 20026286 DOI: 10.1016/J.Vph.2009.12.004  0.798
2009 Saraswathi V, Morrow JD, Hasty AH. Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/- mice. The Journal of Nutrition. 139: 2380-6. PMID 19864403 DOI: 10.3945/Jn.109.111567  0.502
2009 Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, et al. Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circulation Research. 105: 1072-82. PMID 19834009 DOI: 10.1161/Circresaha.109.199570  0.434
2009 Saraswathi V, Hasty AH. Inhibition of long-chain acyl coenzyme A synthetases during fatty acid loading induces lipotoxicity in macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1937-43. PMID 19679826 DOI: 10.1161/Atvbaha.109.195362  0.4
2009 Romero-Aleshire MJ, Diamond-Stanic MK, Hasty AH, Hoyer PB, Brooks HL. Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R587-92. PMID 19439618 DOI: 10.1152/Ajpregu.90762.2008  0.466
2009 Gutierrez DA, Puglisi MJ, Hasty AH. Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia. Current Diabetes Reports. 9: 26-32. PMID 19192421 DOI: 10.1007/S11892-009-0006-9  0.519
2009 Coenen KR, Gruen ML, Lee-Young RS, Puglisi MJ, Wasserman DH, Hasty AH. Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice. Diabetologia. 52: 318-28. PMID 19052722 DOI: 10.1007/S00125-008-1221-7  0.808
2009 Batoy SM, Borgmann S, Flick K, Griffith J, Jones JJ, Saraswathi V, Hasty AH, Kaiser P, Wilkins CL. Lipid and phospholipid profiling of biological samples using MALDI Fourier transform mass spectrometry. Lipids. 44: 367-71. PMID 19005715 DOI: 10.1007/S11745-008-3260-8  0.362
2008 Surmi BK, Hasty AH. Macrophage infiltration into adipose tissue: initiation, propagation and remodeling. Future Lipidology. 3: 545-556. PMID 18978945 DOI: 10.2217/17460875.3.5.545  0.805
2008 Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, Nakagawa Y, Yahagi N, Nakakuki M, Hasty AH, Takeuchi Y, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, et al. Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets. Diabetes. 57: 2382-92. PMID 18458149 DOI: 10.2337/Db06-1806  0.312
2008 Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, Nakagawa Y, Takeuchi Y, Kobayashi K, Takahashi A, Suzuki H, Hasty AH, Toyoshima H, Yamada N, Shimano H. Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance. The Journal of Biological Chemistry. 283: 21220-9. PMID 18445590 DOI: 10.1074/Jbc.M801824200  0.525
2008 Stafford JM, Yu F, Printz R, Hasty AH, Swift LL, Niswender KD. Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion. Diabetes. 57: 1482-90. PMID 18332095 DOI: 10.2337/Db07-1702  0.458
2008 Plummer MR, Hasty AH. Atherosclerotic lesion formation and triglyceride storage in obese apolipoprotein AI-deficient mice. The Journal of Nutritional Biochemistry. 19: 664-73. PMID 18280133 DOI: 10.1016/J.Jnutbio.2007.08.009  0.529
2008 Surmi BK, Atkinson RD, Gruen ML, Coenen KR, Hasty AH. The role of macrophage leptin receptor in aortic root lesion formation. American Journal of Physiology. Endocrinology and Metabolism. 294: E488-95. PMID 18182468 DOI: 10.1152/Ajpendo.00374.2007  0.789
2008 Atkinson RD, Coenen KR, Plummer MR, Gruen ML, Hasty AH. Macrophage-derived apolipoprotein E ameliorates dyslipidemia and atherosclerosis in obese apolipoprotein E-deficient mice. American Journal of Physiology. Endocrinology and Metabolism. 294: E284-90. PMID 18029445 DOI: 10.1152/Ajpendo.00601.2007  0.848
2007 Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, ... ... Hasty AH, et al. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Nature Medicine. 13: 1193-202. PMID 17906635 DOI: 10.1038/Nm1662  0.509
2007 Nuotio-Antar AM, Hachey DL, Hasty AH. Carbenoxolone treatment attenuates symptoms of metabolic syndrome and atherogenesis in obese, hyperlipidemic mice. American Journal of Physiology. Endocrinology and Metabolism. 293: E1517-28. PMID 17878220 DOI: 10.1152/Ajpendo.00522.2007  0.824
2007 Gruen ML, Hao M, Piston DW, Hasty AH. Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis. American Journal of Physiology. Cell Physiology. 293: C1481-8. PMID 17728393 DOI: 10.1152/Ajpcell.00062.2007  0.524
2007 Saraswathi V, Gao L, Morrow JD, Chait A, Niswender KD, Hasty AH. Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. The Journal of Nutrition. 137: 1776-82. PMID 17585030 DOI: 10.1093/Jn/137.7.1776  0.398
2007 Hao M, Head WS, Gunawardana SC, Hasty AH, Piston DW. Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction. Diabetes. 56: 2328-38. PMID 17575085 DOI: 10.2337/Db07-0056  0.363
2007 Coenen KR, Hasty AH. Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice. American Journal of Physiology. Endocrinology and Metabolism. 293: E492-9. PMID 17566116 DOI: 10.1152/Ajpendo.00171.2007  0.832
2007 Coenen KR, Gruen ML, Hasty AH. Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice. The Journal of Nutritional Biochemistry. 18: 727-35. PMID 17418556 DOI: 10.1016/J.Jnutbio.2006.12.010  0.825
2007 Coenen KR, Gruen ML, Chait A, Hasty AH. Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue. Diabetes. 56: 564-73. PMID 17327423 DOI: 10.2337/Db06-1375  0.847
2007 Hasty AH, Gruen ML, Terry ES, Surmi BK, Atkinson RD, Gao L, Morrow JD. Effects of vitamin E on oxidative stress and atherosclerosis in an obese hyperlipidemic mouse model. The Journal of Nutritional Biochemistry. 18: 127-33. PMID 16781857 DOI: 10.1016/J.Jnutbio.2006.03.012  0.811
2006 Wang Y, Oeser JK, Yang C, Sarkar S, Hackl SI, Hasty AH, McGuinness OP, Paradee W, Hutton JC, Powell DR, O'Brien RM. Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon. The Journal of Biological Chemistry. 281: 39982-9. PMID 17023421 DOI: 10.1074/Jbc.M605858200  0.399
2006 Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, et al. Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice. Cell Metabolism. 4: 143-54. PMID 16890542 DOI: 10.1016/J.Cmet.2006.06.009  0.394
2006 Saraswathi V, Hasty AH. The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages. Journal of Lipid Research. 47: 1406-15. PMID 16639077 DOI: 10.1194/Jlr.M600159-Jlr200  0.418
2006 Nuotio-Antar AM, Hasty AH, Kovacs WJ. Quantitation and cellular localization of 11beta-HSD1 expression in murine thymus. The Journal of Steroid Biochemistry and Molecular Biology. 99: 93-9. PMID 16621520 DOI: 10.1016/J.Jsbmb.2006.01.011  0.737
2006 Braun NA, Mohler PJ, Weisgraber KH, Hasty AH, Linton MF, Yancey PG, Su YR, Fazio S, Swift LL. Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells. Journal of Lipid Research. 47: 1176-86. PMID 16534141 DOI: 10.1194/Jlr.M500503-Jlr200  0.341
2006 Nakagawa Y, Shimano H, Yoshikawa T, Ide T, Tamura M, Furusawa M, Yamamoto T, Inoue N, Matsuzaka T, Takahashi A, Hasty AH, Suzuki H, Sone H, Toyoshima H, Yahagi N, et al. TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes. Nature Medicine. 12: 107-13. PMID 16327801 DOI: 10.1038/Nm1334  0.39
2006 Liang X, Kanjanabuch T, Mao SL, Hao CM, Tang YW, Declerck PJ, Hasty AH, Wasserman DH, Fogo AB, Ma LJ. Plasminogen activator inhibitor-1 modulates adipocyte differentiation. American Journal of Physiology. Endocrinology and Metabolism. 290: E103-E113. PMID 16144810 DOI: 10.1152/Ajpendo.00605.2004  0.404
2006 Gruen ML, Saraswathi V, Nuotio-Antar AM, Plummer MR, Coenen KR, Hasty AH. Plasma insulin levels predict atherosclerotic lesion burden in obese hyperlipidemic mice. Atherosclerosis. 186: 54-64. PMID 16102772 DOI: 10.1016/J.Atherosclerosis.2005.07.007  0.802
2005 Zhu MY, Hasty AH, Harris C, Linton MF, Fazio S, Swift LL. Physiological relevance of apolipoprotein E recycling: studies in primary mouse hepatocytes. Metabolism: Clinical and Experimental. 54: 1309-15. PMID 16154429 DOI: 10.1016/J.Metabol.2005.04.019  0.429
2005 Gruen ML, Plummer MR, Zhang W, Posey KA, Linton MF, Fazio S, Hasty AH. Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I. Journal of Lipid Research. 46: 2007-14. PMID 15995171 DOI: 10.1194/Jlr.M500181-Jlr200  0.542
2005 Bodary PF, Gu S, Shen Y, Hasty AH, Buckler JM, Eitzman DT. Recombinant leptin promotes atherosclerosis and thrombosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: e119-22. PMID 15947243 DOI: 10.1161/01.Atv.0000173306.47722.Ec  0.47
2005 Su YR, Dove DE, Major AS, Hasty AH, Boone B, Linton MF, Fazio S. Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1. Circulation. 111: 2373-81. PMID 15851589 DOI: 10.1161/01.Cir.0000164236.19860.13  0.497
2005 Hasty AH, Plummer MR, Weisgraber KH, Linton MF, Fazio S, Swift LL. The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I. Journal of Lipid Research. 46: 1433-9. PMID 15805547 DOI: 10.1194/Jlr.M400418-Jlr200  0.396
2004 Matsuzaka T, Shimano H, Yahagi N, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Tomita S, Sekiya M, Hasty A, Nakagawa Y, Sone H, Toyoshima H, Ishibashi S, et al. Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice. Diabetes. 53: 560-9. PMID 14988238 DOI: 10.2337/Diabetes.53.3.560  0.407
2003 Su YR, Ishiguro H, Major AS, Dove DE, Zhang W, Hasty AH, Babaev VR, Linton MF, Fazio S. Macrophage apolipoprotein A-I expression protects against atherosclerosis in ApoE-deficient mice and up-regulates ABC transporters. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 576-83. PMID 14529830 DOI: 10.1016/S1525-0016(03)00214-4  0.497
2003 Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, et al. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. Molecular Endocrinology (Baltimore, Md.). 17: 1240-54. PMID 12730331 DOI: 10.1210/Me.2002-0190  0.312
2003 Raffaï RL, Hasty AH, Wang Y, Mettler SE, Sanan DA, Linton MF, Fazio S, Weisgraber KH. Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance. The Journal of Biological Chemistry. 278: 11670-5. PMID 12551940 DOI: 10.1074/Jbc.M212873200  0.434
2003 Farkas MH, Swift LL, Hasty AH, Linton MF, Fazio S. The recycling of apolipoprotein E in primary cultures of mouse hepatocytes. Evidence for a physiologic connection to high density lipoprotein metabolism. The Journal of Biological Chemistry. 278: 9412-7. PMID 12524433 DOI: 10.1074/Jbc.M208026200  0.359
2002 Fazio S, Babaev VR, Burleigh ME, Major AS, Hasty AH, Linton MF. Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice. Journal of Lipid Research. 43: 1602-9. PMID 12364544 DOI: 10.1194/Jlr.M200108-Jlr200  0.507
2002 Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, et al. Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice. The Journal of Biological Chemistry. 277: 19353-7. PMID 11923308 DOI: 10.1074/Jbc.M201584200  0.579
2001 Yoshida H, Hasty AH, Major AS, Ishiguro H, Su YR, Gleaves LA, Babaev VR, Linton MF, Fazio S. Isoform-specific effects of apolipoprotein E on atherogenesis gene transduction studies in mice Circulation. 104: 2820-2825. PMID 11733401 DOI: 10.1161/Hc4801.100034  0.447
2001 Hasty AH, Shimano H, Osuga J, Namatame I, Takahashi A, Yahagi N, Perrey S, Iizuka Y, Tamura Y, Amemiya-Kudo M, Yoshikawa T, Okazaki H, Ohashi K, Harada K, Matsuzaka T, et al. Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor. The Journal of Biological Chemistry. 276: 37402-8. PMID 11445560 DOI: 10.1074/Jbc.M010176200  0.53
2001 Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, et al. Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Molecular and Cellular Biology. 21: 2991-3000. PMID 11287605 DOI: 10.1128/Mcb.21.9.2991-3000.2001  0.308
2000 Hasty AH, Shimano H, Yahagi N, Amemiya-Kudo M, Perrey S, Yoshikawa T, Osuga J, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Harada K, Gotoda T, Nagai R, et al. Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level. The Journal of Biological Chemistry. 275: 31069-77. PMID 10913129 DOI: 10.1074/Jbc.M003335200  0.301
1999 Yahagi N, Shimano H, Hasty AH, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids. The Journal of Biological Chemistry. 274: 35840-4. PMID 10585468 DOI: 10.1074/Jbc.274.50.35840  0.409
1999 Shimano H, Yahagi N, Amemiya-Kudo M, Hasty AH, Osuga J, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K, Harada K, Gotoda T, Ishibashi S, Yamada N. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. The Journal of Biological Chemistry. 274: 35832-9. PMID 10585467 DOI: 10.1074/Jbc.274.50.35832  0.39
1999 Hasty AH, Linton MF, Brandt SJ, Babaev VR, Gleaves LA, Fazio S. Retroviral gene therapy in apoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation Circulation. 99: 2571-2576. PMID 10330390 DOI: 10.1161/01.Cir.99.19.2571  0.512
1999 Fazio S, Linton MF, Hasty AH, Swift LL. Recycling of apolipoprotein E in mouse liver Journal of Biological Chemistry. 274: 8247-8253. PMID 10075730 DOI: 10.1074/Jbc.274.12.8247  0.375
1998 Linton MF, Hasty AH, Babaev VR, Fazio S. Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor Journal of Clinical Investigation. 101: 1726-1736. PMID 9541504 DOI: 10.1172/Jci2181  0.401
1997 Fazio S, Babaev VR, Murray AB, Hasty AH, Carter KJ, Gleaves LA, Atkinson JB, Linton MF. Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages. Proceedings of the National Academy of Sciences of the United States of America. 94: 4647-52. PMID 9114045 DOI: 10.1073/Pnas.94.9.4647  0.532
Show low-probability matches.