Todd M. Brusko, Ph.D. - Publications

Affiliations: 
2006 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Immunology, Cell Biology

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM. Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis. Diabetes. PMID 31826866 DOI: 10.2337/db19-0942  0.56
2019 Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, et al. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. PMID 31753960 DOI: 10.2337/dc19-0880  0.56
2019 Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, ... ... Brusko TM, et al. An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes. The Journal of Experimental Medicine. PMID 31467037 DOI: 10.1084/jem.20190430  0.56
2019 Shapiro MR, Atkinson MA, Brusko TM. Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 31145130 DOI: 10.1097/MED.0000000000000484  0.56
2019 Lewis JS, Stewart JM, Marshall GP, Carstens MR, Zhang Y, Dolgova NV, Xia C, Brusko TM, Wasserfall CH, Clare-Salzler MJ, Atkinson MA, Keselowsky BG. Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model. Acs Biomaterials Science & Engineering. 5: 2631-2646. PMID 31119191 DOI: 10.1021/acsbiomaterials.9b00332  0.56
2018 Jacobsen LM, Newby BN, Perry DJ, Posgai AL, Haller MJ, Brusko TM. Immune Mechanisms and Pathways Targeted in Type 1 Diabetes. Current Diabetes Reports. 18: 90. PMID 30168021 DOI: 10.1007/s11892-018-1066-5  0.48
2018 Perry DJ, Wasserfall CH, Oram RA, Williams MD, Posgai A, Muir AB, Haller MJ, Schatz DA, Wallet MA, Mathews CE, Atkinson MA, Brusko TM. Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. Scientific Reports. 8: 4529. PMID 29540798 DOI: 10.1038/s41598-018-22574-5  0.56
2017 Jacobsen LM, Posgai A, Seay HR, Haller MJ, Brusko TM. T Cell Receptor Profiling in Type 1 Diabetes. Current Diabetes Reports. 17: 118. PMID 29022222 DOI: 10.1007/s11892-017-0946-4  0.48
2017 Chen J, Chernatynskaya AV, Li JW, Kimbrell MR, Cassidy RJ, Perry DJ, Muir AB, Atkinson MA, Brusko TM, Mathews CE. T cells display mitochondria hyperpolarization in human type 1 diabetes. Scientific Reports. 7: 10835. PMID 28883439 DOI: 10.1038/s41598-017-11056-9  0.56
2017 Newby BN, Brusko TM, Zou B, Atkinson MA, Clare-Salzler M, Mathews CE. Type 1 Interferons Potentiate Human CD8(+) T Cell Cytotoxicity Through a STAT4 and Granzyme B Dependent Pathway. Diabetes. PMID 28877912 DOI: 10.2337/db17-0106  0.56
2017 Marcial GE, Ford AL, Haller MJ, Gezan SA, Harrison NA, Cai D, Meyer JL, Perry DJ, Atkinson MA, Wasserfall CH, Garrett T, Gonzalez CF, Brusko TM, Dahl WJ, Lorca GL. Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults. Frontiers in Immunology. 8: 655. PMID 28659913 DOI: 10.3389/fimmu.2017.00655  0.56
2017 Seay HR, Putnam AL, Cserny J, Posgai AL, Rosenau EH, Wingard JR, Girard KF, Kraus M, Lares AP, Brown HL, Brown KS, Balavage KT, Peters LD, Bushdorf AN, Atkinson MA, ... ... Brusko TM, et al. Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy. Molecular Therapy. Methods & Clinical Development. 4: 178-191. PMID 28345003 DOI: 10.1016/j.omtm.2016.12.003  0.56
2017 Li X, Campbell-Thompson M, Wasserfall CH, McGrail K, Posgai A, Schultz AR, Brusko TM, Shuster J, Liang F, Muir A, Schatz D, Haller MJ, Atkinson MA. Serum Trypsinogen Levels in Type 1 Diabetes. Diabetes Care. PMID 28115475 DOI: 10.2337/dc16-1774  0.56
2016 Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, ... ... Brusko TM, et al. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. Jci Insight. 1: e88242. PMID 27942583 DOI: 10.1172/jci.insight.88242  0.56
2016 Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Perry DJ, Schultz AR, Hulme MA, Shuster JJ, Zou B, Wasserfall CH, Posgai A, Mathews CE, Brusko TM, Atkinson MA, Schatz DA. Anti-Thymocyte Globulin + G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders with Established Type 1 Diabetes. Diabetes. PMID 27669730 DOI: 10.2337/db16-0823  0.56
2015 Haller MJ, Atkinson MA, Wasserfall CH, Brusko TM, Mathews CE, Hulme M, Cintron M, Shuster J, McGrail K, Posgai A, Schatz D. Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes. Clinical and Experimental Immunology. PMID 26462724 DOI: 10.1111/cei.12731  0.48
2015 Fuhrman CA, Yeh WI, Seay HR, Saikumar Lakshmi P, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, von Schack D, ... ... Brusko TM, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. Journal of Immunology (Baltimore, Md. : 1950). 195: 145-55. PMID 25994968 DOI: 10.4049/jimmunol.1402381  0.56
2015 Yin Y, Choi SC, Xu Z, Perry DJ, Seay H, Croker BP, Sobel ES, Brusko TM, Morel L. Normalization of CD4+ T cell metabolism reverses lupus. Science Translational Medicine. 7: 274ra18. PMID 25673763 DOI: 10.1126/scitranslmed.aaa0835  0.48
2015 Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Rosenthal SM, Shuster JJ, Zou B, Brusko TM, Hulme MA, Wasserfall CH, Mathews CE, Atkinson MA, Schatz DA. Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. The Journal of Clinical Investigation. 125: 448-55. PMID 25500887 DOI: 10.1172/JCI78492  0.48
2014 Lewis JS, Roche C, Zhang Y, Brusko TM, Wasserfall CH, Atkinson M, Clare-Salzler MJ, Keselowsky BG. Combinatorial delivery of immunosuppressive factors to dendritic cells using dual-sized microspheres. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 2562-2574. PMID 24778809 DOI: 10.1039/C3TB21460E  0.48
2013 Gjymishka A, Coman RM, Brusko TM, Glover SC. Influence of host immunoregulatory genes, ER stress and gut microbiota on the shared pathogenesis of inflammatory bowel disease and Type 1 diabetes. Immunotherapy. 5: 1357-66. PMID 24283846 DOI: 10.2217/imt.13.130  0.48
2013 Mueller C, Chulay JD, Trapnell BC, Humphries M, Carey B, Sandhaus RA, McElvaney NG, Messina L, Tang Q, Rouhani FN, Campbell-Thompson M, Fu AD, Yachnis A, Knop DR, Ye GJ, ... ... Brusko TM, et al. Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression. The Journal of Clinical Investigation. 123: 5310-8. PMID 24231351 DOI: 10.1172/JCI70314  0.48
2013 Myhr CB, Hulme MA, Wasserfall CH, Hong PJ, Lakshmi PS, Schatz DA, Haller MJ, Brusko TM, Atkinson MA. The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFNγ production by PBMC. Journal of Autoimmunity. 44: 8-12. PMID 23891168 DOI: 10.1016/j.jaut.2013.06.001  0.48
2013 Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM, Wingard JR, Theriaque DW, Shuster JJ, Ferguson RJ, Kozuch M, Clare-Salzler M, Atkinson MA, Schatz DA. Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 1126-9. PMID 23611977 DOI: 10.1016/j.bbmt.2013.04.011  0.48
2012 Thompson JA, Perry D, Brusko TM. Autologous regulatory T cells for the treatment of type 1 diabetes. Current Diabetes Reports. 12: 623-32. PMID 22843491 DOI: 10.1007/s11892-012-0304-5  0.48
2012 Hulme MA, Wasserfall CH, Atkinson MA, Brusko TM. Central role for interleukin-2 in type 1 diabetes. Diabetes. 61: 14-22. PMID 22187370 DOI: 10.2337/db11-1213  0.48
2011 Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM, Sumrall TM, Wingard JR, Theriaque DW, Shuster JJ, Atkinson MA, Schatz DA. Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care. 34: 2567-9. PMID 22011412 DOI: 10.2337/dc11-1406  0.48
2011 McClymont SA, Putnam AL, Lee MR, Esensten JH, Liu W, Hulme MA, Hoffmüller U, Baron U, Olek S, Bluestone JA, Brusko TM. Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 3918-26. PMID 21368230 DOI: 10.4049/jimmunol.1003099  0.48
2010 Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, Nishimura MI, Han S, Chang LJ, Atkinson MA, Ribas A, Bluestone JA. Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. Plos One. 5: e11726. PMID 20668510 DOI: 10.1371/journal.pone.0011726  0.48
2009 Brusko TM, Wasserfall CH, Hulme MA, Cabrera R, Schatz D, Atkinson MA. Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation. Plos One. 4: e7980. PMID 19956753 DOI: 10.1371/journal.pone.0007980  0.48
2009 Haller MJ, Wasserfall CH, McGrail KM, Cintron M, Brusko TM, Wingard JR, Kelly SS, Shuster JJ, Atkinson MA, Schatz DA. Autologous umbilical cord blood transfusion in very young children with type 1 diabetes. Diabetes Care. 32: 2041-6. PMID 19875605 DOI: 10.2337/dc09-0967  0.48
2009 Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, Atkinson MA, Bluestone JA. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes. 58: 652-62. PMID 19074986 DOI: 10.2337/db08-1168  0.48
2008 Xue S, Wasserfall CH, Parker M, Brusko TM, McGrail S, McGrail K, Moore M, Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ. Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency. Annals of the New York Academy of Sciences. 1150: 152-6. PMID 19120286 DOI: 10.1196/annals.1447.049  0.48
2008 Stalvey MS, Brusko TM, Mueller C, Wasserfall CH, Schatz DA, Atkinson MA, Flotte TR. CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes. Cytokine. 44: 154-9. PMID 18778952 DOI: 10.1016/j.cyto.2008.07.468  0.48
2008 Brusko TM, Putnam AL, Bluestone JA. Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunological Reviews. 223: 371-90. PMID 18613848 DOI: 10.1111/j.1600-065X.2008.00637.x  0.48
2008 George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH, Atkinson MA, Agarwal A, Kapturczak MH. Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. The American Journal of Pathology. 173: 154-60. PMID 18511516 DOI: 10.2353/ajpath.2008.070963  0.48
2007 Brusko TM, Hulme MA, Myhr CB, Haller MJ, Atkinson MA. Assessing the in vitro suppressive capacity of regulatory T cells. Immunological Investigations. 36: 607-28. PMID 18161521 DOI: 10.1080/08820130701790368  0.48
2006 Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE, Brusko TM, Wasserfall CH, Wu J, Atkinson MA, Gao Z, Kaestner KH, Wolf BA. PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene. 369: 134-41. PMID 16412588 DOI: 10.1016/j.gene.2005.10.040  0.48
2005 Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4 +CD25+ T-cells in type 1 diabetes Diabetes. 54: 1407-1414. PMID 15855327 DOI: 10.2337/diabetes.54.5.1407  0.48
2005 Brusko TM, Wasserfall CH, Agarwal A, Kapturczak MH, Atkinson MA. An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 5181-6. PMID 15843512  0.48
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