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Jun Chen - Publications

Affiliations: 
BME Duke University, Durham, NC 
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zheng X, Lu R, Pan D, Peng L, He R, Hu Y, Chen J, Tang J, Rong X, Teng S, Wang Y, Liu F, Xie T, Wu C, Tang Y, et al. TREG cells and CXCR3+ circulating TFH cells concordantly shape the neutralizing antibody responses in individuals who have recovered from mild COVID-19. The Journal of Infectious Diseases. PMID 38324762 DOI: 10.1093/infdis/jiae061  0.309
2018 Tang R, Jing L, Willard VP, Wu CL, Guilak F, Chen J, Setton LA. Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells. Stem Cell Research & Therapy. 9: 61. PMID 29523190 DOI: 10.1186/S13287-018-0797-1  0.668
2017 Bridgen DT, Fearing BV, Jing L, Sanchez-Adams J, Cohan MC, Guilak F, Chen J, Setton LA. Regulation of Human Nucleus Pulposus Cells by Peptide-Coupled Substrates. Acta Biomaterialia. PMID 28433788 DOI: 10.1016/J.Actbio.2017.04.019  0.798
2016 Hwang PY, Jing L, Chen J, Lim FL, Tang R, Choi H, Cheung KM, Risbud MV, Gersbach CA, Guilak F, Leung VY, Setton LA. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. Scientific Reports. 6: 28038. PMID 27292569 DOI: 10.1038/Srep28038  0.808
2016 Su X, Yu M, Qiu G, Zheng Y, Chen Y, Wen R, Fu G, Zhu W, Chen J, Wu N, Ma P, Chen W, Wu Z, Wang D. Evaluation of nestin or osterix promoter-driven cre/loxp system in studying the biological functions of murine osteoblastic cells. American Journal of Translational Research. 8: 1447-59. PMID 27186271  0.303
2016 Tang X, Jing L, Richardson WJ, Isaacs RE, Fitch RD, Brown CR, Erickson MM, Setton LA, Chen J. Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27018499 DOI: 10.1002/Jor.23244  0.823
2015 Hwang PY, Jing L, Michael KW, Richardson WJ, Chen J, Setton LA. N-Cadherin-Mediated Signaling Regulates Cell Phenotype for Nucleus Pulposus Cells of the Intervertebral Disc. Cellular and Molecular Bioengineering. 8: 51-62. PMID 25848407 DOI: 10.1007/S12195-014-0373-4  0.8
2014 Karikari IO, Gilchrist CL, Jing L, Alcorta DA, Chen J, Richardson WJ, Gabr MA, Bell RD, Kelley MJ, Bagley CA, Setton LA. Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines. Journal of Neurosurgery. Spine. 21: 386-93. PMID 24905390 DOI: 10.3171/2014.4.Spine13262  0.773
2014 Hwang PY, Chen J, Jing L, Hoffman BD, Setton LA. The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review. Journal of Biomechanical Engineering. 136: 021010. PMID 24390195 DOI: 10.1115/1.4026360  0.804
2014 Francisco AT, Hwang PY, Jeong CG, Jing L, Chen J, Setton LA. Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration. Acta Biomaterialia. 10: 1102-11. PMID 24287160 DOI: 10.1016/J.Actbio.2013.11.013  0.799
2014 Tang X, Richardson WJ, Fitch RD, Brown CR, Isaacs RE, Chen J. A new non-enzymatic method for isolating human intervertebral disc cells preserves the phenotype of nucleus pulposus cells. Cytotechnology. 66: 979-86. PMID 24101443 DOI: 10.1007/S10616-013-9650-7  0.794
2014 Tang X, Jing L, Setton LA, Richardson WJ, Fitch RD, Isaacs RE, Brown CR, Michael KW, Chen J. Cell Phenotype and Matrix Regeneration of Human Nucleus Pulposus Cells of Different Ages in a Laminin-Rich Pseudo-3D Culture System in Vitro Global Spine Journal. 4: s-0034-1376648-s-003. DOI: 10.1055/S-0034-1376648  0.625
2014 Hwang PY, Jing L, Richardson WJ, Isaacs RE, Michael KW, Chen J, Setton LA. N-Cadherin-Mediated Cell Signaling in Nucleus Pulposus Cells of the Intervertebral Disc Global Spine Journal. 4: s-0034-1376616-s-003. DOI: 10.1055/S-0034-1376616  0.762
2013 Chon BH, Lee EJ, Jing L, Setton LA, Chen J. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system. Stem Cell Research & Therapy. 4: 120. PMID 24405888 DOI: 10.1186/Scrt331  0.678
2013 Chen J, Lee EJ, Jing L, Christoforou N, Leong KW, Setton LA. Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro. Plos One. 8: e75548. PMID 24086564 DOI: 10.1371/Journal.Pone.0075548  0.676
2013 Bridgen DT, Gilchrist CL, Richardson WJ, Isaacs RE, Brown CR, Yang KL, Chen J, Setton LA. Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1661-7. PMID 23737292 DOI: 10.1002/Jor.22395  0.821
2012 Tang X, Jing L, Chen J. Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging. Plos One. 7: e52020. PMID 23284858 DOI: 10.1371/Journal.Pone.0052020  0.768
2012 Jing L, So S, Lim SW, Richardson WJ, Fitch RD, Setton LA, Chen J. Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1923-31. PMID 22692729 DOI: 10.1002/Jor.22158  0.692
2012 Tang X, Jing L, Setton LA, Richardson WJ, Fitch RD, Isaacs RE, Brown CR, Chen J. Novel Molecular Phenotype of Notochordal-Like Cells in Nucleus Pulposus of Human Intervertebral Disk Global Spine Journal. 2: s-0032-1319965-s-003. DOI: 10.1055/S-0032-1319965  0.61
2011 Gilchrist CL, Darling EM, Chen J, Setton LA. Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions. Plos One. 6: e27170. PMID 22087260 DOI: 10.1371/Journal.Pone.0027170  0.837
2011 Gilchrist CL, Francisco AT, Plopper GE, Chen J, Setton LA. Nucleus pulposus cell-matrix interactions with laminins. European Cells & Materials. 21: 523-32. PMID 21710443  0.817
2011 Sinclair SM, Shamji MF, Chen J, Jing L, Richardson WJ, Brown CR, Fitch RD, Setton LA. Attenuation of inflammatory events in human intervertebral disc cells with a tumor necrosis factor antagonist. Spine. 36: 1190-6. PMID 21217452 DOI: 10.1016/S1063-4584(09)60554-9  0.801
2011 Gabr MA, Jing L, Helbling AR, Sinclair SM, Allen KD, Shamji MF, Richardson WJ, Fitch RD, Setton LA, Chen J. Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1-7. PMID 20665551 DOI: 10.1002/Jor.21206  0.774
2010 Shamji MF, Setton LA, Jarvis W, So S, Chen J, Jing L, Bullock R, Isaacs RE, Brown C, Richardson WJ. Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues. Arthritis and Rheumatism. 62: 1974-82. PMID 20222111 DOI: 10.1002/Art.27444  0.709
2010 Li J, Zhang S, Chen J, Du T, Wang Y, Wang Z. Modeled microgravity causes changes in the cytoskeleton and focal adhesions, and decreases in migration in malignant human MCF-7 cells. Protoplasma. 238: 23-33. PMID 19730978 DOI: 10.1007/s00709-009-0068-1  0.319
2009 Chen J, Jing L, Gilchrist CL, Richardson WJ, Fitch RD, Setton LA. Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. Connective Tissue Research. 50: 294-306. PMID 19863388 DOI: 10.3109/03008200802714925  0.83
2009 Chen J, Jing L, Gilchrist C, Richardson W, Fitch R, Setton L. Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc Connective Tissue Research. 50: 294-306. DOI: 10.3109/03008200802714925  0.559
2009 Gabr M, Setton L, Sinclair S, Jing L, Brown C, Richardson W, Chen J. 498 A T-CELL ASSOCIATED CYTOKINE, INTERLEUKIN-17, PROMOTES AN INFLAMMATORY PHENOTYPE IN DEGENERATIVE HUMAN INTERVERTEBRAL DISC CELLS Osteoarthritis and Cartilage. 17: S268. DOI: 10.1016/S1063-4584(09)60519-7  0.792
2008 Shamji MF, Jing L, Chen J, Hwang P, Ghodsizadeh O, Friedman AH, Richardson WJ, Setton LA. Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier. Journal of Neurosurgery. Spine. 9: 221-8. PMID 18764758 DOI: 10.3171/Spi/2008/9/8/221  0.783
2008 Shamji MF, Chen J, Friedman AH, Richardson WJ, Chilkoti A, Setton LA. Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist. Journal of Controlled Release : Official Journal of the Controlled Release Society. 129: 179-86. PMID 18547669 DOI: 10.1016/J.Jconrel.2008.04.021  0.692
2008 Boyd LM, Richardson WJ, Allen KD, Flahiff C, Jing L, Li Y, Chen J, Setton LA. Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen. Arthritis and Rheumatism. 58: 164-71. PMID 18163498 DOI: 10.1002/Art.23231  0.781
2008 Shamji MF, Allen KD, Adams SB, So S, Jing L, Chen J, Richardson WJ, Setton LA. GAIT ABNORMALITIES AND SENSORY CHANGES ACCOMPANY NEURO-INFLAMMATION IN ANIMAL MODELS OF DISC HERNIATION RADICULOPATHY Clinical & Investigative Medicine. 31: 21. DOI: 10.25011/Cim.V31I4.4825  0.788
2008 Chen J, Boyd LM, Allen KD, Tsuboyama M, Jing L, Malfait A, Setton LA. Degenerative Changes Of Intervertebral Disc And Vertebral Endplate In Adamts5 (Aggrecanase-2) Knockout Mice Spine. 109. DOI: 10.1097/01.Brs.0000320268.32700.2D  0.723
2007 Shamji MF, Betre H, Kraus VB, Chen J, Chilkoti A, Pichika R, Masuda K, Setton LA. Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. Arthritis and Rheumatism. 56: 3650-61. PMID 17968946 DOI: 10.1002/Art.22952  0.762
2007 Gilchrist CL, Chen J, Richardson WJ, Loeser RF, Setton LA. Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 829-40. PMID 17318895 DOI: 10.1002/Jor.20343  0.82
2007 Brodsky SV, Merks RM, Mendelev N, Goo C, Chen J. Glycated Collagen I (GC) impairs angiogenesis in vitro: a study using an innovative chamber for cell research. Diabetes Research and Clinical Practice. 76: 463-7. PMID 17084479 DOI: 10.1016/j.diabres.2006.10.003  0.311
2007 Shamji M, Betre H, Chen J, Kraus V, Chilkoti A, Setton L. 418 DEVELOPMENT OF A THERMALLY RESPONSIVE DRUG DEPOT FOR INTRA-ARTICULAR DELIVERY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST TO ATTENUATE INFLAMMATORY EVENTS IN OSTEOARTHRITIS Osteoarthritis and Cartilage. 15: C226-C227. DOI: 10.1016/S1063-4584(07)62049-4  0.745
2007 Chen J, Boyd L, Allen K, Tsuboyama M, Jing L, Malfait A, Setton L. 31 EVALUATION OF INTERVERTEBRAL DISC AND VERTEBRAL ENDPLATE DEGENERATION IN ADAMTS5 (AGGRECANASE-2) KNOCKOUT MICE Osteoarthritis and Cartilage. 15: C31-C32. DOI: 10.1016/S1063-4584(07)61667-7  0.748
2007 Chen J, Jing L, Gilchrist C, Richardson W, Fitch R, Setton L. P137 Expression of laminin binding receptors is a unique feature of immature nucleus pulposus cells Osteoarthritis and Cartilage. 15: B122. DOI: 10.1016/S1063-4584(07)61492-7  0.788
2006 Upton ML, Chen J, Setton LA. Region-specific constitutive gene expression in the adult porcine meniscus. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1562-70. PMID 16732608 DOI: 10.1002/Jor.20146  0.804
2006 Setton LA, Chen J. Mechanobiology of the intervertebral disc and relevance to disc degeneration. The Journal of Bone and Joint Surgery. American Volume. 88: 52-7. PMID 16595444 DOI: 10.2106/Jbjs.F.00001  0.63
2006 Chen J, Yan W, Setton LA. Molecular phenotypes of notochordal cells purified from immature nucleus pulposus. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 15: S303-11. PMID 16547755 DOI: 10.1007/S00586-006-0088-X  0.705
2006 Hyun J, Chen J, Setton LA, Chilkoti A. Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression. Biomaterials. 27: 1444-51. PMID 16154191 DOI: 10.1016/J.Biomaterials.2005.08.018  0.618
2006 Boyd L, Clapp M, Richardson W, Odom D, Jing L, Chen J, Setton L. Static compression modulates gene expression in the murine intervertebral disc in vitro Journal of Biomechanics. 39: S27. DOI: 10.1016/S0021-9290(06)82976-3  0.733
2005 Boyd LM, Richardson WJ, Chen J, Kraus VB, Tewari A, Setton LA. Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. Annals of Biomedical Engineering. 33: 1071-7. PMID 16133915 DOI: 10.1007/S10439-005-5775-Y  0.76
2004 Setton LA, Chen J. Cell mechanics and mechanobiology in the intervertebral disc. Spine. 29: 2710-23. PMID 15564920 DOI: 10.1097/01.Brs.0000146050.57722.2A  0.636
2004 Boyd LM, Chen J, Kraus VB, Setton LA. Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. Spine. 29: 2217-22. PMID 15480131 DOI: 10.1097/01.Brs.0000142747.90488.1D  0.811
2004 Chen J, Vistica BP, Takase H, Ham DI, Fariss RN, Wawrousek EF, Chan CC, DeMartino JA, Farber JM, Gery I. A unique pattern of up- and down-regulation of chemokine receptor CXCR3 on inflammation-inducing Th1 cells. European Journal of Immunology. 34: 2885-94. PMID 15368305 DOI: 10.1002/eji.200425318  0.307
2004 Chen J, Yan W, Setton LA. Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 573-83. PMID 14996437 DOI: 10.1016/J.Matbio.2003.11.008  0.652
2004 Setton LA, Chen J. Intervertebral disc cell mechanics and biological responses to load Current Opinion in Orthopaedics. 15: 331-340. DOI: 10.1097/01.Bco.0000134822.79609.C6  0.631
2003 Upton ML, Chen J, Guilak F, Setton LA. Differential effects of static and dynamic compression on meniscal cell gene expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 963-9. PMID 14554206 DOI: 10.1016/S0736-0266(03)00063-9  0.782
2002 Chen J, Baer AE, Paik PY, Yan W, Setton LA. Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. Biochemical and Biophysical Research Communications. 293: 932-8. PMID 12051748 DOI: 10.1016/S0006-291X(02)00314-5  0.812
2001 Chen J, Reeves L, Cornetta K. Safety testing for replication-competent retrovirus associated with gibbon ape leukemia virus-pseudotyped retroviral vectors. Human Gene Therapy. 12: 61-70. PMID 11177543 DOI: 10.1089/104303401450979  0.317
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