| Year |
Citation |
Score |
| 2024 |
Khamrui S, Dodatko T, Wu R, Leandro J, Sabovic A, Violante S, Cross JR, Marsan E, Kumar K, DeVita RJ, Lazarus MB, Houten SM. Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. Biorxiv : the Preprint Server For Biology. PMID 38370847 DOI: 10.1101/2024.02.07.578422 |
0.305 |
|
| 2022 |
Leandro J, Khamrui S, Suebsuwong C, Chen PJ, Secor C, Dodatko T, Yu C, Sanchez R, DeVita RJ, Houten SM, Lazarus MB. Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biology. 12: 220179. PMID 36128717 DOI: 10.1098/rsob.220179 |
0.736 |
|
| 2021 |
Wang P, Karakose E, Choleva L, Kumar K, DeVita RJ, Garcia-Ocaña A, Stewart AF. Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges. Frontiers in Endocrinology. 12: 671946. PMID 34335466 DOI: 10.3389/fendo.2021.671946 |
0.607 |
|
| 2021 |
He Z, Chen L, Catalan-Dibene J, Bongers G, Faith JJ, Suebsuwong C, DeVita RJ, Shen Z, Fox JG, Lafaille JJ, Furtado GC, Lira SA. Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23. Cell Metabolism. PMID 33989521 DOI: 10.1016/j.cmet.2021.04.015 |
0.693 |
|
| 2021 |
Kumar K, Suebsuwong C, Wang P, Garcia-Ocana A, Stewart AF, DeVita RJ. DYRK1A Inhibitors as Potential Therapeutics for β-Cell Regeneration for Diabetes. Journal of Medicinal Chemistry. PMID 33682417 DOI: 10.1021/acs.jmedchem.0c02050 |
0.714 |
|
| 2021 |
Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33602808 DOI: 10.1073/pnas.2007328118 |
0.722 |
|
| 2020 |
Leandro J, Khamrui S, Wang H, Suebsuwong C, Nemeria NS, Huynh K, Moustakim M, Secor C, Wang M, Dodatko T, Stauffer B, Wilson CG, Yu C, Arkin MR, Jordan F, ... ... DeVita RJ, et al. Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. Acs Chemical Biology. PMID 32633484 DOI: 10.1021/Acschembio.0C00114 |
0.649 |
|
| 2020 |
Kumar K, Wang P, A Swartz E, Khamrui S, Secor C, B Lazarus M, Sanchez R, F Stewart A, DeVita RJ. Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation. Molecules (Basel, Switzerland). 25. PMID 32340326 DOI: 10.3390/Molecules25081983 |
0.699 |
|
| 2020 |
Leandro J, Dodatko T, Aten J, Nemeria NS, Zhang X, Jordan F, Hendrickson RC, Sanchez R, Yu C, DeVita RJ, Houten SM. DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo. Human Molecular Genetics. PMID 32160276 DOI: 10.1093/Hmg/Ddaa037 |
0.349 |
|
| 2020 |
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, et al. GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration. Science Translational Medicine. 12. PMID 32051230 DOI: 10.1126/Scitranslmed.Aaw9996 |
0.691 |
|
| 2020 |
Kumar K, Wang P, Wilson J, Zlatanic V, Berrouet C, Khamrui S, Secor C, Swartz E, Lazarus MB, Sanchez R, Stewart AF, Garcia-Ocana A, DeVita RJ. Synthesis and Biological Validation of a Harmine-based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. Journal of Medicinal Chemistry. PMID 32003560 DOI: 10.1021/Acs.Jmedchem.9B01379 |
0.702 |
|
| 2019 |
Ackeifi C, Swartz E, Kumar K, Liu H, Chalada S, Karakose E, Scott DK, Garcia-Ocaña A, Sanchez R, DeVita RJ, Stewart AF, Wang P. Pharmacologic and genetic approaches define human pancreatic beta cell mitogenic targets of DYRK1A inhibitors. Jci Insight. PMID 31821176 DOI: 10.1172/Jci.Insight.132594 |
0.648 |
|
| 2019 |
Ung PM, DeVita RJ, Schlessinger A. Encounter and React: Computer-Guided Design of Covalent Inhibitors. Cell Chemical Biology. 26: 6-8. PMID 30658111 DOI: 10.1016/J.Chembiol.2018.12.009 |
0.358 |
|
| 2018 |
Kumar K, Man-Un Ung P, Wang P, Wang H, Li H, Andrews MK, Stewart AF, Schlessinger A, DeVita RJ. Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity. European Journal of Medicinal Chemistry. 157: 1005-1016. PMID 30170319 DOI: 10.1016/J.Ejmech.2018.08.007 |
0.745 |
|
| 2018 |
Kumar K, Wang P, Sanchez R, Swartz E, Stewart AF, DeVita RJ. Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation. Journal of Medicinal Chemistry. PMID 30059217 DOI: 10.1021/Acs.Jmedchem.8B00658 |
0.699 |
|
| 2018 |
Chang CJ, Kotini AG, Olszewska M, Georgomanoli M, Teruya-Feldstein J, Sperber H, Sanchez R, DeVita R, Martins TJ, Abdel-Wahab O, Bradley RK, Papapetrou EP. Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs. Stem Cell Reports. PMID 29681544 DOI: 10.1016/J.Stemcr.2018.03.020 |
0.332 |
|
| 2010 |
Howell KL, DeVita RJ, Garcia-Calvo M, Meurer RD, Lisnock J, Bull HG, McMasters DR, McCann ME, Mills SG. Spiroimidazolidinone NPC1L1 inhibitors. Part 2: structure-activity studies and in vivo efficacy. Bioorganic & Medicinal Chemistry Letters. 20: 6929-32. PMID 21030254 DOI: 10.1016/j.bmcl.2010.09.138 |
0.3 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2020 |
Leandro J, Dodatko T, DeVita RJ, Chen H, Stauffer B, Yu C, Houten SM. Deletion of 2-aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1. Journal of Inherited Metabolic Disease. PMID 32567100 DOI: 10.1002/Jimd.12276 |
0.299 |
|
| 2021 |
Wu K, Hopkins BD, Sanchez R, DeVita RJ, Pan ZQ. Targeting Cullin-RING E3 Ubiquitin Ligase 4 by Small Molecule Modulators. Journal of Cellular Signaling. 2: 195-205. PMID 34604860 DOI: 10.33696/Signaling.2.051 |
0.299 |
|
| 2024 |
Wu K, DeVita RJ, Pan ZQ. Modulation of Cullin-RING E3 ubiquitin ligase-dependent ubiquitination by small molecule compounds. The Journal of Biological Chemistry. 105752. PMID 38354780 DOI: 10.1016/j.jbc.2024.105752 |
0.296 |
|
| 2015 |
Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ. Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nature Communications. 6: 7229. PMID 26068603 DOI: 10.1038/Ncomms8229 |
0.287 |
|
| 2014 |
He S, Hong Q, Lai Z, Yang DX, Ting PC, Kuethe JT, Cernak TA, Dykstra KD, Sperbeck DM, Wu Z, Yu Y, Yang GX, Jian T, Liu J, Guiadeen D, ... ... DeVita RJ, et al. Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety. Acs Medicinal Chemistry Letters. 5: 1082-7. PMID 25349648 DOI: 10.1021/ml5003426 |
0.265 |
|
| 2013 |
DeVita RJ, Pinto S. Current status of the research and development of diacylglycerol O-acyltransferase 1 (DGAT1) inhibitors. Journal of Medicinal Chemistry. 56: 9820-5. PMID 23919406 DOI: 10.1021/jm4007033 |
0.264 |
|
| 2018 |
White KM, Abreu P, Wang H, De Jesus PD, Manicassamy B, García-Sastre A, Chanda SK, DeVita RJ, Shaw ML. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein. Acs Infectious Diseases. PMID 29268608 DOI: 10.1021/Acsinfecdis.7B00120 |
0.263 |
|
| 2023 |
Houten SM, Dodatko T, Dwyer W, Violante S, Chen H, Stauffer B, DeVita RJ, Vaz FM, Cross JR, Yu C, Leandro J. Acyl-CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism. Journal of Inherited Metabolic Disease. PMID 37309295 DOI: 10.1002/jimd.12642 |
0.261 |
|
| 2014 |
Muise ES, Zhu Y, Verras A, Karanam BV, Gorski J, Weingarth D, Lin HV, Hwa J, Thompson JR, Hu G, Liu J, He S, DeVita RJ, Shen DM, Pinto S. Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors. Plos One. 9: e88908. PMID 24558447 DOI: 10.1371/journal.pone.0088908 |
0.244 |
|
| 2024 |
Wu K, DeVita RJ, Pan ZQ. Mono-ubiquitination empowers ubiquitin chain elongation. The Journal of Biological Chemistry. 105753. PMID 38354782 DOI: 10.1016/j.jbc.2024.105753 |
0.242 |
|
| 2016 |
Manigrasso MB, Pan J, Rai V, Zhang J, Reverdatto S, Quadri N, DeVita RJ, Ramasamy R, Shekhtman A, Schmidt AM. Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction. Scientific Reports. 6: 22450. PMID 26936329 DOI: 10.1038/Srep22450 |
0.238 |
|
| 2017 |
Cernak T, Gesmundo NJ, Dykstra K, Yu Y, Wu Z, Shi ZC, Vachal P, Sperbeck D, He S, Murphy BA, Sonatore L, Williams S, Madeira M, Verras A, Reiter M, ... ... DeVita RJ, et al. Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors. Journal of Medicinal Chemistry. PMID 28252959 DOI: 10.1021/Acs.Jmedchem.6B01543 |
0.227 |
|
| 2008 |
Morriello GJ, Devita RJ, Mills SG, Young JR, Lin P, Doss G, Chicchi GG, Demartino J, Kurtz MM, Tsao KL, Carlson E, Townson K, Wheeldon A, Boyce S, Collinson N, et al. Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists. Bioorganic & Medicinal Chemistry. 16: 2156-70. PMID 18248994 DOI: 10.1016/J.Bmc.2007.11.081 |
0.225 |
|
| 2019 |
He S, Lai Z, Hong Q, Shang J, Reibarkh M, Kuethe JT, Liu J, Guiadeen D, Krikorian AD, Cernak TA, Dykstra KD, Sperbeck DM, Wu Z, Yu Y, Yang GX, ... ... DeVita RJ, et al. Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety. Bioorganic & Medicinal Chemistry Letters. PMID 30926247 DOI: 10.1016/j.bmcl.2019.03.025 |
0.219 |
|
| 2010 |
Morriello GJ, Mills SG, Johnson T, Reibarkh M, Chicchi G, DeMartino J, Kurtz M, Davies P, Tsao KL, Zheng S, Tong X, Carlson E, Townson K, Tattersall FD, Wheeldon A, ... ... DeVita RJ, et al. Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK1 antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 2007-12. PMID 20153964 DOI: 10.1016/j.bmcl.2010.01.065 |
0.217 |
|
| 2024 |
Dar AA, Ortega Y, Aktas S, Wu K, Guha I, Porter N, Rosen S, DeVita RJ, Pan ZQ, Oliver PM. CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression. Journal of Immunology (Baltimore, Md. : 1950). PMID 38265261 DOI: 10.4049/jimmunol.2300754 |
0.213 |
|
| 2013 |
He S, Hong Q, Lai Z, Wu Z, Yu Y, Kim DW, Ting PC, Kuethe JT, Yang GX, Jian T, Liu J, Guiadeen D, Krikorian AD, Sperbeck DM, Sonatore LM, ... ... DeVita RJ, et al. Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety. Acs Medicinal Chemistry Letters. 4: 773-8. PMID 24900745 DOI: 10.1021/ml400168h |
0.212 |
|
| 2014 |
Chobanian HR, Guo Y, Liu P, Chioda MD, Fung S, Lanza TJ, Chang L, Bakshi RK, Dellureficio JP, Hong Q, McLaughlin M, Belyk KM, Krska SW, Makarewicz AK, Martel EJ, ... ... DeVita RJ, et al. Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain. Acs Medicinal Chemistry Letters. 5: 717-21. PMID 24944750 DOI: 10.1021/Ml5001239 |
0.208 |
|
| 2020 |
Manigrasso MB, Quadri NA, Frye LE, D’Agati V, DeVita RJ, Ramasamy R, Shekhtman A, Schmidt AM. Novel Therapeutic Opportunities for Diabetic Complications using a Small Molecule Antagonist of RAGE/DIAPH1 Interaction The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03475 |
0.206 |
|
| 2019 |
Focken T, Burford K, Grimwood ME, Zenova A, Andrez JC, Gong W, Wilson M, Taron M, Decker S, Lofstrand V, Chowdhury S, Shuart N, Lin S, Goodchild SJ, Young C, ... ... Devita RJ, et al. Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy. Journal of Medicinal Chemistry. PMID 31525968 DOI: 10.1021/Acs.Jmedchem.9B01032 |
0.203 |
|
| 2007 |
Young JR, Eid R, Turner C, DeVita RJ, Kurtz MM, Tsao KL, Chicchi GG, Wheeldon A, Carlson E, Mills SG. Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 5310-5. PMID 17723300 DOI: 10.1016/J.Bmcl.2007.08.028 |
0.2 |
|
| 2013 |
Kassick AJ, Jiang J, Bunda J, Wilson D, Bao J, Lu H, Lin P, Ball RG, Doss GA, Tong X, Tsao KL, Wang H, Chicchi G, Karanam B, Tschirret-Guth R, ... ... DeVita RJ, et al. 2-[(3aR,4R,5S,7aS)-5-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2H-isoindol-2-yl]-1,3-oxazol-4(5H)-one: a potent human NK1 receptor antagonist with multiple clearance pathways. Journal of Medicinal Chemistry. 56: 5940-8. PMID 23808489 DOI: 10.1021/Jm400751P |
0.198 |
|
| 2021 |
Manigrasso MB, Rabbani P, Egaña-Gorroño L, Quadri N, Frye L, Zhou B, Reverdatto S, Ramirez LS, Dansereau S, Pan J, Li H, D'Agati VD, Ramasamy R, DeVita RJ, Shekhtman A, et al. Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice. Science Translational Medicine. 13: eabf7084. PMID 34818060 DOI: 10.1126/scitranslmed.abf7084 |
0.186 |
|
| 2009 |
McMasters DR, Garcia-Calvo M, Maiorov V, McCann ME, Meurer RD, Bull HG, Lisnock J, Howell KL, DeVita RJ. Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening Bioorganic and Medicinal Chemistry Letters. 19: 2965-2968. PMID 19410454 DOI: 10.1016/j.bmcl.2009.04.031 |
0.183 |
|
| 2010 |
Morriello GJ, Chicchi G, Johnson T, Mills SG, Demartino J, Kurtz M, Tsao KL, Zheng S, Tong X, Carlson E, Townson K, Wheeldon A, Boyce S, Collinson N, Rupniak N, ... Devita RJ, et al. Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK1 receptor. Bioorganic & Medicinal Chemistry Letters. 20: 5925-32. PMID 20729082 DOI: 10.1016/j.bmcl.2010.07.058 |
0.183 |
|
| 2007 |
DeVita RJ. Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1-R) antagonists. Current Topics in Medicinal Chemistry. 7: 1433-9. PMID 17897030 |
0.179 |
|
| 2007 |
Lin P, Chang L, Devita RJ, Young JR, Eid R, Tong X, Zheng S, Ball RG, Tsou NN, Chicchi GG, Kurtz MM, Tsao KL, Wheeldon A, Carlson EJ, Eng W, et al. The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine. Bioorganic & Medicinal Chemistry Letters. 17: 5191-8. PMID 17637506 DOI: 10.1016/J.Bmcl.2007.06.085 |
0.176 |
|
| 2010 |
Bao J, Lu H, Morriello GJ, Carlson EJ, Wheeldon A, Chicchi GG, Kurtz MM, Tsao KL, Zheng S, Tong X, Mills SG, DeVita RJ. Tetrahydroindolizinone NK1 antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 2354-8. PMID 20188553 DOI: 10.1016/j.bmcl.2010.01.120 |
0.169 |
|
| 2023 |
Yeganeh M, Auray-Blais C, Maranda B, Sabovic A, DeVita RJ, Lazarus MB, Houten SM. A case of hyperlysinemia identified by urine newborn screening. Jimd Reports. 64: 440-445. PMID 37927488 DOI: 10.1002/jmd2.12399 |
0.161 |
|
| 2001 |
DeVita RJ, Walsh TF, Young JR, Jiang J, Ujjainwalla F, Toupence RB, Parikh M, Huang SX, Fair JA, Goulet MT, Wyvratt MJ, Lo JL, Ren N, Yudkovitz JB, Yang YT, et al. A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor. Journal of Medicinal Chemistry. 44: 917-22. PMID 11300873 DOI: 10.1021/Jm000275P |
0.144 |
|
| 2009 |
Jiang J, Bunda JL, Doss GA, Chicchi GG, Kurtz MM, Tsao KL, Tong X, Zheng S, Upthagrove A, Samuel K, Tschirret-Guth R, Kumar S, Wheeldon A, Carlson EJ, Hargreaves R, ... ... DeVita RJ, et al. Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists. Journal of Medicinal Chemistry. 52: 3039-46. PMID 19354254 DOI: 10.1021/Jm8016514 |
0.14 |
|
| 2004 |
DeVita RJ, Parikh M, Jiang J, Fair JA, Young JR, Walsh TF, Goulet MT, Lo JL, Ren N, Yudkovitz JB, Cui J, Yang YT, Cheng K, Rohrer SP, Wyvratt MJ. Identification of neutral 4-O-alkyl quinolone nonpeptide GnRH receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 5599-603. PMID 15482932 DOI: 10.1016/J.Bmcl.2004.08.056 |
0.136 |
|
| 2009 |
Simeone JP, Braun MP, Leone JF, Lin P, DeVita RJ, Garcia-Calvo M, Bull HG, Lisnock J, Dean DC. Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand. Bioorganic & Medicinal Chemistry Letters. 19: 5033-6. PMID 19631535 DOI: 10.1016/j.bmcl.2009.07.051 |
0.136 |
|
| 1988 |
Kende AS, DeVita RJ. Synthesis of the fused bicyclic lactam-lactone terminus of neooxazolomycin by a novel dianion cyclocondensation Tetrahedron Letters. 29: 2521-2524. DOI: 10.1016/S0040-4039(00)86101-8 |
0.132 |
|
| 2006 |
Jiang J, Hoang M, Young JR, Chaung D, Eid R, Turner C, Lin P, Tong X, Wang J, Tan C, Feighner S, Palyha O, Hreniuk DL, Pan J, Sailer AW, ... ... DeVita RJ, et al. 2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 5270-4. PMID 16919456 DOI: 10.1016/J.Bmcl.2006.08.006 |
0.131 |
|
| 1999 |
DeVita RJ, Hollings DD, Goulet MT, Wyvratt MJ, Fisher MH, Lo JL, Yang YT, Cheng K, Smith RG. Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 9: 2615-20. PMID 10498220 DOI: 10.1016/S0960-894X(99)00446-1 |
0.13 |
|
| 2011 |
McLaren DG, He T, Wang SP, Mendoza V, Rosa R, Gagen K, Bhat G, Herath K, Miller PL, Stribling S, Taggart A, Imbriglio J, Liu J, Chen D, Pinto S, ... ... Devita RJ, et al. The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species. Journal of Lipid Research. 52: 1150-61. PMID 21415123 DOI: 10.1194/Jlr.M011049 |
0.126 |
|
| 2019 |
Liu K, Kurukulasuriya R, Dykstra K, DiMichelle L, Liu J, Vachal P, Ogawa A, DeVita RJ, Shen DM, Tan Q, Chen Y, Gauthier D, Verras A, Crespo A, Zamlynny B, et al. Development of indazole mineralocorticoid receptor antagonists and investigation into their selective late-stage functionalization. Bioorganic & Medicinal Chemistry Letters. PMID 31104995 DOI: 10.1016/J.Bmcl.2019.04.024 |
0.124 |
|
| 2006 |
Jiang J, Lin P, Hoang M, Chang L, Tan C, Feighner S, Palyha OC, Hreniuk DL, Pan J, Sailer AW, Morin NR, MacNeil DJ, Howard AD, Van der Ploeg LH, Goulet MT, ... DeVita RJ, et al. 4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 5275-9. PMID 16919453 DOI: 10.1016/j.bmcl.2006.08.008 |
0.123 |
|
| 2013 |
Liu P, Hamill TG, Chioda M, Chobanian H, Fung S, Guo Y, Chang L, Bakshi R, Hong Q, Dellureficio J, Lin LS, Abbadie C, Alexander J, Jin H, Mandala S, ... ... DeVita RJ, et al. Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase. Acs Medicinal Chemistry Letters. 4: 509-13. PMID 24900701 DOI: 10.1021/Ml4000996 |
0.113 |
|
| 2021 |
Canning BJ, Liu Q, Tao M, DeVita R, Perelman M, Hay DW, Dicpinigaitis PV, Liang J. . The Journal of Pharmacology and Experimental Therapeutics. PMID 34782407 DOI: 10.1124/jpet.121.000641 |
0.11 |
|
| 2000 |
Cui J, Smith RG, Mount GR, Lo JL, Yu J, Walsh TF, Singh SB, DeVita RJ, Goulet MT, Schaeffer JM, Cheng K. Identification of Phe313 of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists. Molecular Endocrinology (Baltimore, Md.). 14: 671-81. PMID 10809231 DOI: 10.1210/mend.14.5.0464 |
0.109 |
|
| 1999 |
DeVita RJ, Goulet MT, Wyvratt MJ, Fisher MH, Lo JL, Yang YT, Cheng K, Smith RG. Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 9: 2621-4. PMID 10498221 DOI: 10.1016/S0960-894X(99)00447-3 |
0.106 |
|
| 2000 |
Walsh TF, Toupence RB, Young JR, Huang SX, Ujjainwalla F, DeVita RJ, Goulet MT, Wyvratt MJ, Fisher MH, Lo JL, Ren N, Yudkovitz JB, Yang YT, Cheng K, Smith RG. Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides. Bioorganic & Medicinal Chemistry Letters. 10: 443-7. PMID 10743944 DOI: 10.1016/S0960-894X(00)00024-X |
0.105 |
|
| 2005 |
DeVita RJ. Small molecule mimetics of GHRP-6. Expert Opinion On Investigational Drugs. 6: 1839-43. PMID 15989584 DOI: 10.1517/13543784.6.12.1839 |
0.101 |
|
| 2004 |
Jiang J, DeVita RJ, Goulet MT, Wyvratt MJ, Lo JL, Ren N, Yudkovitz JB, Cui J, Yang YT, Cheng K, Rohrer SP. Syntheses and structure-activity relationship studies of piperidine-substituted quinolones as nonpeptide gonadotropin releasing hormone antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 1795-8. PMID 15026074 DOI: 10.1016/j.bmcl.2003.12.101 |
0.1 |
|
| 1988 |
KENDE AS, DEVITA RJ. ChemInform Abstract: Synthesis of the Fused Bicyclic Lactam-Lactone Terminus of Neooxazolomycin by a Novel Dianion Cyclocondensation. Cheminform. 19. DOI: 10.1002/CHIN.198847162 |
0.097 |
|
| 1994 |
Schoen WR, Ok D, DeVita RJ, Pisano JM, Hodges P, Cheng K, Chan WWS, Butler BS, Smith RG, Wyvratt MJ, Fisher MH. Structure-activity relationships in the amino acid sidechain of L-692,429 Bioorganic and Medicinal Chemistry Letters. 4: 1117-1122. DOI: 10.1016/S0960-894X(01)80239-0 |
0.091 |
|
| 2010 |
ARMSTRONG JDI, WOLFE CN, KELLER JL, LYNCH J, BHUPATHY M, VOLANTE RP, DEVITA RJ. ChemInform Abstract: A Novel Synthesis of Disubstituted Ureas Using Titanium(IV) Isopropoxide and Sodium Borohydride. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199725082 |
0.085 |
|
| 1998 |
DeVita RJ, Bochis R, Frontier AJ, Kotliar A, Fisher MH, Schoen WR, Wyvratt MJ, Cheng K, Chan WW, Butler B, Jacks TM, Hickey GJ, Schleim KD, Leung K, Chen Z, et al. A potent, orally bioavailable benzazepinone growth hormone secretagogue. Journal of Medicinal Chemistry. 41: 1716-28. PMID 9572898 DOI: 10.1021/Jm970816J |
0.085 |
|
| 1994 |
Ok D, Schoen WR, Hodges P, DeVita RJ, Brown JE, Cheng K, Chan WWS, Butler BS, Smith RG, Fisher MH, Wyvratt MJ. Structure-activity relationships of the non-peptidyl growth hormone secretagogue L-692,429 Bioorganic and Medicinal Chemistry Letters. 4: 2709-2714. DOI: 10.1016/S0960-894X(01)80702-2 |
0.085 |
|
| 1992 |
KAWAMURA K, DeVita R, Kende A. Total Synthesis of Neooxazolomycin. Journal of Synthetic Organic Chemistry, Japan. 50: 61-70. DOI: 10.5059/Yukigoseikyokaishi.50.61 |
0.083 |
|
| 2010 |
YOUNG JR, DEVITA RJ. ChemInform Abstract: Novel Synthesis of Oxadiazoles via Palladium Catalysis. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199833177 |
0.081 |
|
| 2003 |
Jiang J, Shah H, DeVita RJ. Synthesis of 4-trifluoromethylated 2-alkyl- and 2,3-dialkyl-substituted azetidines. Organic Letters. 5: 4101-3. PMID 14572259 DOI: 10.1021/ol030099p |
0.069 |
|
| 2020 |
Devita R, Chagarlamudi K, Kardan A. Synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget's disease in a case of newly diagnosed prostatic carcinoma. World Journal of Nuclear Medicine. 19: 144-146. PMID 32939203 DOI: 10.4103/wjnm.WJNM_63_19 |
0.068 |
|
| 1990 |
Kende AS, DeVita RJ. A mild four-carbon homologation of aldehydes to E,E-dienamines Tetrahedron Letters. 31: 307-310. DOI: 10.1016/S0040-4039(00)94540-4 |
0.06 |
|
| 1990 |
KENDE AS, DEVITA RJ. ChemInform Abstract: A Mild Four-Carbon Homologation of Aldehydes to E,E-Dienamines. Cheminform. 21. DOI: 10.1002/CHIN.199037130 |
0.056 |
|
| 1987 |
LUMMA WCJ, WOHL RA, DAVEY DD, ARGENTIERI TM, DEVITA RJ, GOMEZ RP, JAIN VK, MARISCA AJ, MORGAN TKJ, REISER HJ, SULLIVAN ME, WIGGINS J, WONG SS. ChemInform Abstract: Rational Design of 4-((Methylsulfonyl)amino)benzamides as Class III Antiarrhythmic Agents. Cheminform. 18. DOI: 10.1002/CHIN.198746155 |
0.054 |
|
| 2020 |
DeVita R, Faraji N, Nakfoor R, Elliott R, Kosmas C. Hyaline fibromatosis syndrome: A rare case of multifocal intra-articular involvement. Clinical Imaging. 70: 51-55. PMID 33120290 DOI: 10.1016/j.clinimag.2020.10.015 |
0.051 |
|
| 2000 |
Young JR, Huang SX, Chen I, Walsh TF, DeVita RJ, Wyvratt MJ, Goulet MT, Ren N, Lo J, Yang YT, Yudkovitz JB, Cheng K, Smith RG. Quinolones as gonadotropin releasing hormone (GnRH) antagonists: simultaneous optimization of the C(3)-aryl and C(6)-substituents. Bioorganic & Medicinal Chemistry Letters. 10: 1723-7. PMID 10937733 DOI: 10.1016/S0960-894X(00)00318-8 |
0.049 |
|
| 2011 |
Cernak T, Dykstra K, Levorse D, Verras A, Balkovec J, Nargund R, DeVita R. Synthesis of oxaspiropiperidines as a strategy for lowering logD Tetrahedron Letters. 52: 6457-6459. DOI: 10.1016/j.tetlet.2011.09.100 |
0.048 |
|
| 2003 |
Elmore CS, Dean DC, DeVita RJ, Melillo DG. Synthesis of two non-peptidyl GnRH receptor antagonists via [ 14C]carbonylation Journal of Labelled Compounds and Radiopharmaceuticals. 46: 993-1000. DOI: 10.1002/jlcr.733 |
0.046 |
|
| 1998 |
Young JR, DeVita RJ. Novel synthesis of oxadiazoles via palladium catalysis Tetrahedron Letters. 39: 3931-3934. DOI: 10.1016/S0040-4039(98)00719-9 |
0.041 |
|
| 1994 |
DeVita RJ, Schoen WR, Fisher MH, Frontier AJ, Pisano JM, Wyvratt MJ, Cheng K, Chan WWS, Butler BS, Hickey GJ, Jacks TM, Smith RG. Benzolactam growth hormone secretagogues: Carboxamides as replacements for the 2′-tetrazole moiety of L-692,429 Bioorganic and Medicinal Chemistry Letters. 4: 2249-2254. DOI: 10.1016/S0960-894X(00)80080-3 |
0.037 |
|
| 1994 |
DeVita RJ, Schoen WR, Ok D, Barash L, Brown JE, Fisher MH, Hodges P, Wyvratt MJ, Cheng K, Chan WWS, Butler BS, Smith RG. Benzolactam growth hormone secretagogues: replacements for the 2′-tetrazole moiety of L-692,429 Bioorganic and Medicinal Chemistry Letters. 4: 1807-1812. DOI: 10.1016/S0960-894X(01)80375-9 |
0.035 |
|
| 1999 |
Jiang J, DeVita RJ, Doss GA, Goulet MT, Wyvratt MJ. Asymmetric synthesis of chiral, nonracemic trifluoromethyl-substituted piperidines and decahydroquinolines Journal of the American Chemical Society. 121: 593-594. DOI: 10.1021/ja983389n |
0.031 |
|
| 1991 |
Oppolzer W, DeVita RJ. Direct syntheses of polyfused ring systems by intramolecular tandem palladium-ene/Heck insertion reactions The Journal of Organic Chemistry. 56: 6256-6257. DOI: 10.1021/JO00022A004 |
0.03 |
|
| 1995 |
DeVita RJ, Schoen WR, Doldouras GA, Fisher MH, Wyvratt MJ, Cheng K, Chan WWS, Butler BS, Smith RG. Heterocyclic analogs of the benzolactam nucleus of the non-peptidic growth hormone secretagogue L-692,429 Bioorganic and Medicinal Chemistry Letters. 5: 1281-1286. DOI: 10.1016/0960-894X(95)00209-C |
0.03 |
|
| 2010 |
Jiang J, DeVita RJ, Doss GA, Goulet MT, Wyvratt MJ. ChemInform Abstract: Asymmetric Synthesis of Chiral, Nonracemic Trifluoromethyl-Substituted Piperidines and Decahydroquinolines. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199925133 |
0.029 |
|
| 2021 |
Fischer J, Ali A, DeVita RJ. IUPAC-Richter Prize Call for Nominations. Journal of Medicinal Chemistry. 64: 13937. PMID 34606261 DOI: 10.1021/acs.jmedchem.1c01651 |
0.029 |
|
| 2010 |
DeVita RJ, Goulet MT, Wyvratt MJ, Fisher MH, Lo J, Yang YT, Cheng K, Smith RG. ChemInform Abstract: Investigation of the 4-O-Alkylamine Substituent of Non-peptide Quinolone GnRH Receptor Antagonists. Cheminform. 30: no-no. DOI: 10.1002/chin.199949130 |
0.028 |
|
| 2010 |
OPPOLZER W, DEVITA RJ. ChemInform Abstract: Direct Synthesis of Polyfused Ring Systems by Intramolecular Tandem Palladium-Ene/Heck Insertion Reactions. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199217130 |
0.026 |
|
| 1990 |
Kende AS, Kawamura K, DeVita RJ. Enantioselective total synthesis of neooxazolomycin Journal of the American Chemical Society. 112: 4070-4072. DOI: 10.1021/JA00166A072 |
0.024 |
|
| 1990 |
Kende AS, Kawamura K, DeVita RJ. Enantioselective total synthesis of neooxazolomycin Journal of the American Chemical Society. 112: 4070-4072. DOI: 10.1021/Ja00166A072 |
0.024 |
|
| 2019 |
Chagarlamudi K, Devita R, Barr RG. Gastric Lipoma: A Review of the Literature. Ultrasound Quarterly. 34: 119-121. PMID 29369244 DOI: 10.1097/RUQ.0000000000000338 |
0.019 |
|
| 1996 |
DeVita R, Wyvratt M. Benzolactam growth hormone secretagogues Drugs of the Future. 21: 273. DOI: 10.1358/DOF.1996.021.03.353289 |
0.013 |
|
| 2021 |
Devita R, Chagarlamudi K, Durieux J, Jordan D, Nguyen B, Davidson J, Kosaraju V, Abboud S. Omission of Planning CT Reduces Patient Radiation Exposure during CT-Guided Bone Marrow Biopsy and Aspiration. Tomography (Ann Arbor, Mich.). 7: 747-751. PMID 34842812 DOI: 10.3390/tomography7040062 |
0.012 |
|
| 2020 |
Radetic M, DeVita R, Haaga J. When is contrast needed for abdominal and pelvic CT? Cleveland Clinic Journal of Medicine. 87: 595-598. PMID 33004318 DOI: 10.3949/ccjm.87a.19093 |
0.01 |
|
| 2017 |
Barr RG, DeVita R, Destounis S, Manzoni F, De Silvestri A, Tinelli C. Agreement Between an Automated Volume Breast Scanner and Handheld Ultrasound for Diagnostic Breast Examinations. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. 36: 2087-2092. PMID 28569407 DOI: 10.1002/jum.14248 |
0.01 |
|
| 2016 |
DeVita R, Barr RG. Effect of Precompression on the Power Doppler Assessment of Breast Lesion Vascularity. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. PMID 27925701 DOI: 10.7863/ultra.16.01024 |
0.01 |
|
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