Year |
Citation |
Score |
2019 |
Goryanova B, Amyes TL, Richard JP. Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization. Journal of the American Chemical Society. PMID 31365243 DOI: 10.1021/Jacs.9B04823 |
0.605 |
|
2015 |
Goryanova B, Goldman LM, Ming S, Amyes TL, Gerlt JA, Richard JP. Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate Decarboxylase. Biochemistry. 54: 4555-64. PMID 26135041 DOI: 10.1021/Acs.Biochem.5B00591 |
0.64 |
|
2014 |
Goldman LM, Amyes TL, Goryanova B, Gerlt JA, Richard JP. Enzyme architecture: Deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5′-monophosphate decarboxylase Journal of the American Chemical Society. 136: 10156-10165. PMID 24958125 DOI: 10.1021/Ja505037V |
0.648 |
|
2014 |
Richard JP, Amyes TL, Goryanova B, Zhai X. Enzyme architecture: on the importance of being in a protein cage. Current Opinion in Chemical Biology. 21: 1-10. PMID 24699188 DOI: 10.1016/J.Cbpa.2014.03.001 |
0.595 |
|
2013 |
Goryanova B, Goldman LM, Amyes TL, Gerlt JA, Richard JP. Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5′-phosphate decarboxylase-catalyzed reactions Biochemistry. 52: 7500-7511. PMID 24053466 DOI: 10.1021/Bi401117Y |
0.671 |
|
2013 |
Goryanova B, Spong K, Amyes TL, Richard JP. Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates. Biochemistry. 52: 537-46. PMID 23276261 DOI: 10.1021/Bi301650D |
0.655 |
|
2012 |
Desai BJ, Wood BM, Fedorov AA, Fedorov EV, Goryanova B, Amyes TL, Richard JP, Almo SC, Gerlt JA. Conformational changes in orotidine 5′-monophosphate decarboxylase: A structure-based explanation for how the 5′-phosphate group activates the enzyme Biochemistry. 51: 8665-8678. PMID 23030629 DOI: 10.1021/Bi301188K |
0.605 |
|
2011 |
Goryanova B, Amyes TL, Gerlt JA, Richard JP. OMP decarboxylase: Phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate Journal of the American Chemical Society. 133: 6545-6548. PMID 21486036 DOI: 10.1021/Ja201734Z |
0.634 |
|
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