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Wesley P. Wong - Publications

Affiliations: 
Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
Area:
Single-molecule Force Studies
Website:
http://www.fas.harvard.edu/~biophys/Wesley_P_Wong.htm
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shrestha P, Yang D, Ward A, Shih WM, Wong WP. Mapping Single-Molecule Protein Complexes in 3D with DNA Nanoswitch Calipers. Journal of the American Chemical Society. PMID 38096567 DOI: 10.1021/jacs.3c10262  0.638
2023 Shrestha P, Yang D, Shih WM, Wong WP. Mapping Single-molecule Protein Complexes in 3D with DNA Nanoswitch Calipers. Biorxiv : the Preprint Server For Biology. PMID 37502860 DOI: 10.1101/2023.07.10.548386  0.638
2023 Vilcapoma J, Aliyeva A, Hayden A, Chandrasekaran AR, Zhou L, Abraham Punnoose J, Yang D, Hansen C, Shiu SC, Russell A, George KS, Wong WP, Halvorsen K. A non-enzymatic test for SARS-CoV-2 RNA using DNA nanoswitches. Medrxiv : the Preprint Server For Health Sciences. PMID 37398235 DOI: 10.1101/2023.05.31.23290613  0.542
2023 Luo Y, Chang J, Yang D, Bryan JS, MacIsaac M, Pressé S, Wong WP. Resolving Molecular Heterogeneity with Single-Molecule Centrifugation. Journal of the American Chemical Society. PMID 36716175 DOI: 10.1021/jacs.2c11450  0.619
2022 Bergal HT, Jiang Y, Yang D, Springer TA, Wong WP. Conformation of von Willebrand factor in shear flow revealed with stroboscopic single-molecule imaging. Blood. PMID 36040485 DOI: 10.1182/blood.2022016969  0.605
2021 Fu H, Jiang Y, Wong WP, Springer TA. Single-molecule imaging of von Willebrand factor reveals tension-dependent self-association. Blood. 138: 2425-2434. PMID 34882208 DOI: 10.1182/blood.2021012595  0.312
2021 Shrestha P, Yang D, Tomov TE, MacDonald JI, Ward A, Bergal HT, Krieg E, Cabi S, Luo Y, Nathwani B, Johnson-Buck A, Shih WM, Wong WP. Single-molecule mechanical fingerprinting with DNA nanoswitch calipers. Nature Nanotechnology. PMID 34675411 DOI: 10.1038/s41565-021-00979-0  0.622
2021 Mulhall EM, Ward A, Yang D, Koussa MA, Corey DP, Wong WP. Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection. Nature Communications. 12: 849. PMID 33558532 DOI: 10.1038/s41467-021-21033-6  0.623
2021 Chandrasekaran AR, MacIsaac M, Vilcapoma J, Hansen CH, Yang D, Wong WP, Halvorsen K. DNA Nanoswitch Barcodes for Multiplexed Biomarker Profiling. Nano Letters. PMID 33395311 DOI: 10.1021/acs.nanolett.0c03929  0.556
2020 Jiang Y, Feldman T, Bakx JAM, Yang D, Wong WP. Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping. Lab On a Chip. PMID 32301470 DOI: 10.1039/C9Lc01028A  0.689
2020 Huoh YS, Wu B, Park S, Yang D, Bansal K, Greenwald E, Wong WP, Mathis D, Hur S. Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance. Nature Communications. 11: 1625. PMID 32242017 DOI: 10.1038/S41467-020-15448-W  0.568
2019 Jiang Y, Fu H, Springer TA, Wong WP. Electrostatic Steering Enables Flow-Activated von Willebrand Factor to Bind Platelet Glycoprotein, Revealed by Single-Molecule Stretching and Imaging. Journal of Molecular Biology. PMID 30797858 DOI: 10.1016/J.Jmb.2019.02.014  0.433
2018 Nathwani B, Shih WM, Wong WP. Force Spectroscopy and Beyond: Innovations and Opportunities. Biophysical Journal. PMID 30447991 DOI: 10.1016/J.Bpj.2018.10.021  0.419
2018 Yang D, Wong WP. Repurposing a Benchtop Centrifuge for High-Throughput Single-Molecule Force Spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 1665: 353-366. PMID 28940079 DOI: 10.1007/978-1-4939-7271-5_19  0.685
2018 Hansen CH, Blass J, Yang D, Wong WP. Gel-Based and Single Molecule Nanoswitch-Linked Immunosorbent Assays (NLISA and smNLISA) for Sensitive and Specific Protein Detection Biophysical Journal. 114: 692a. DOI: 10.1016/J.Bpj.2017.11.3732  0.619
2018 Dai M, MacDonald J, Vigneault F, Hernandez E, Yang D, Wong W, Yin P. Single-Molecule Protein Identification Through Peptide Chain Barcoding and Optical Readout Biophysical Journal. 114: 531a. DOI: 10.1016/J.Bpj.2017.11.2906  0.585
2018 Luo Y, Yang D, MacIsaac M, Wong WP. High-Throughput Single-Molecule Characterization of Antibody-Antigen Interaction using Centrifuge Force Microscopy Biophysical Journal. 114: 355a-356a. DOI: 10.1016/J.Bpj.2017.11.1978  0.635
2018 Jiang Y, Fu H, Yang D, Scheiflinger F, Springer TA, Wong WP. Stretching and Activation of Single Protein Molecules by Flow Reveals the Mechanism of von Willebrand Factor Adhesion Biophysical Journal. 114: 18a. DOI: 10.1016/J.Bpj.2017.11.142  0.65
2018 Wong WP. Exploring Nanoscale Biomechanics with Parallel Force Spectroscopy Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.044  0.376
2017 Hansen CH, Yang D, Koussa MA, Wong WP. Nanoswitch-linked immunosorbent assay (NLISA) for fast, sensitive, and specific protein detection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893984 DOI: 10.1073/Pnas.1708148114  0.613
2017 Fu H, Jiang Y, Yang D, Scheiflinger F, Wong WP, Springer TA. Flow-induced elongation of von Willebrand factor precedes tension-dependent activation. Nature Communications. 8: 324. PMID 28831047 DOI: 10.1038/S41467-017-00230-2  0.627
2017 Nathwani B, Yang D, Wong W, Shih WM. Exploring Nucleic Acid Mechanics using Multiplexed Mechanochemistry Assay (MMA) Biophysical Journal. 112: 166a. DOI: 10.1016/J.Bpj.2016.11.916  0.555
2016 Yang D, Wong WP. Small but Mighty: Nanoparticles Probe Cellular Signaling Pathways. Developmental Cell. 37: 397-398. PMID 27270039 DOI: 10.1016/J.Devcel.2016.05.021  0.622
2016 Yang D, Ward A, Halvorsen K, Wong WP. Multiplexed single-molecule force spectroscopy using a centrifuge. Nature Communications. 7: 11026. PMID 26984516 DOI: 10.1038/Ncomms11026  0.676
2016 Jiang Y, Feldman TC, Kang H, De La Cruz EM, Wong WP. Tension-Regulated Actin Severing Revealed by Surface-Free Single-Molecule Force Spectroscopy Biophysical Journal. 110: 95a. DOI: 10.1016/J.Bpj.2015.11.571  0.405
2016 Yang D, Ward AR, Halvorsen K, Wong WP. Multiplexed Force Spectroscopy using DNA Nanoswitch a Centrifuge Biophysical Journal. 110: 635a. DOI: 10.1016/J.Bpj.2015.11.3402  0.662
2016 Nathwani B, Yang D, Wong W, Shih WM. Multiplexed Mechanochemistry Assay - A Tool for Multiplexed Single Molecule Bond Rupture Force Studies Biophysical Journal. 110: 501a. DOI: 10.1016/J.Bpj.2015.11.2677  0.661
2016 Fu H, Jiang Y, Yang D, Wong WP, Springer TA. Single-Molecule Activation by Flow: Force-Induced Conformational Transitions Regulate the Ligand Binding Affinity of a Large, Polymeric Mechanosensor Protein Biophysical Journal. 110: 348a. DOI: 10.1016/J.Bpj.2015.11.1873  0.647
2016 Koussa MA, Ward A, Sotomayor M, Wong WP, Corey DP. Single Molecule Force Spectroscopy of Hair-Cell Tip-Link Proteins Biophysical Journal. 110: 196a. DOI: 10.1016/J.Bpj.2015.11.1090  0.485
2015 Koussa MA, Halvorsen K, Ward A, Wong WP. DNA nanoswitches: a quantitative platform for gel-based biomolecular interaction analysis. Nature Methods. 12: 123-6. PMID 25486062 DOI: 10.1038/Nmeth.3209  0.388
2015 Hoang TP, Wong WP, Halvorsen K. Development of a Wireless, Modular Centrifuge Force Microscope for Use in a Commercial Benchtop Centrifuge Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.943  0.456
2015 Koussa MA, Wong WP, Corey DP. Single-Molecule Force-Spectroscopy of Inner Ear Proteins Biophysical Journal. 108: 565a. DOI: 10.1016/J.Bpj.2014.11.3093  0.48
2015 Jiang Y, Wong W. Surface-Free Single-Molecule Force Spectroscopy Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1947  0.456
2015 Wong WP. Revealing the Mechanical Regulation of Hemostasis with Novel Approaches in Single-Molecule Manipulation Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.060  0.505
2014 Koussa MA, Sotomayor M, Wong WP. Protocol for sortase-mediated construction of DNA-protein hybrids and functional nanostructures. Methods (San Diego, Calif.). 67: 134-41. PMID 24568941 DOI: 10.1016/J.Ymeth.2014.02.020  0.347
2014 Halvorsen K, Koussa M, Ward A, Wong WP. Instrument Free Biomolecular Interaction Measurement with DNA Nanoswitches Biophysical Journal. 106: 386a. DOI: 10.1016/J.Bpj.2013.11.2185  0.4
2014 Koussa MA, Sotomayor M, Wong WP, Corey DP. Force Spectroscopy of Tip Link Proteins: A Study of Inner-Ear Biophysics Biophysical Journal. 106: 386a. DOI: 10.1016/J.Bpj.2013.11.2183  0.416
2014 Jiang Y, Fu H, Yang D, Springer TA, Wong WP. Single-Molecule Imaging of Von Willebrand Factor Activation by Flow Biophysical Journal. 106: 194a. DOI: 10.1016/J.Bpj.2013.11.1150  0.651
2013 Yang D, Feldman T, Halvorsen K, Wong W. Elucidating Hydrodynamic Force Regulation of Von Willebrand Factor in Hemostasis Biophysical Journal. 104: 1-8. DOI: 10.1016/J.Bpj.2012.11.944  0.675
2012 Zhao W, Cui CH, Bose S, Guo D, Shen C, Wong WP, Halvorsen K, Farokhzad OC, Teo GS, Phillips JA, Dorfman DM, Karnik R, Karp JM. Bioinspired multivalent DNA network for capture and release of cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 19626-31. PMID 23150586 DOI: 10.1073/Pnas.1211234109  0.34
2012 Halvorsen K, Wong WP. Self-Assembly of a DNA-Based Switchable Linker for Single-Molecule Force Spectroscopy Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.982  0.488
2012 Yang D, Feldman T, Cheng D, Halvorsen K, Wong WP. Single-Molecule Investigations of Von Willebrand Factor in Hydrodynamic Flow Biophysical Journal. 102: 5-8. DOI: 10.1016/J.Bpj.2011.11.3146  0.655
2012 Wong WP. Mechanoregulation in Nanoscale Biology: From Hemostasis to Single-Molecule Centrifugation Biophysical Journal. 102: 4-7. DOI: 10.1016/J.Bpj.2011.11.2223  0.465
2011 Halvorsen K, Schaak D, Wong WP. Nanoengineering a single-molecule mechanical switch using DNA self-assembly. Nanotechnology. 22: 494005. PMID 22101354 DOI: 10.1088/0957-4484/22/49/494005  0.469
2010 Halvorsen K, Wong WP. Massively parallel single-molecule manipulation using centrifugal force. Biophysical Journal. 98: L53-5. PMID 20513382 DOI: 10.1016/J.Bpj.2010.03.012  0.489
2010 Wong WP. Single-Molecule Kinetics Under Force: Probing Protein Folding and Enzymatic Activity with Optical Tweezers Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3248  0.401
2009 Zhang X, Halvorsen K, Zhang CZ, Wong WP, Springer TA. Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor. Science (New York, N.Y.). 324: 1330-4. PMID 19498171 DOI: 10.1126/Science.1170905  0.743
2009 Wong WP, Halvorsen K. Probing Protein Folding Kinetics with High-resolution, Stabilized Optical Tweezers Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1905  0.336
2009 Zhang X, Halvorsen K, Wong WP, Springer TA. Unfolding, refolding and proteolysis of the von Willebrand Factor A2 domain under tensile force Biophysical Journal. 96: 37a. DOI: 10.1016/J.Bpj.2008.12.083  0.349
2008 Heinrich V, Wong WP, Halvorsen K, Evans E. Imaging biomolecular interactions by fast three-dimensional tracking of laser-confined carrier particles. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 1194-203. PMID 18198910 DOI: 10.1021/La7027059  0.573
2006 Wong WP, Halvorsen K. The effect of integration time on fluctuation measurements: calibrating an optical trap in the presence of motion blur. Optics Express. 14: 12517-31. PMID 19529687 DOI: 10.1364/Oe.14.012517  0.304
2005 Wong WP, Evans E. Biological physics: rare returns on lost effort. Nature. 437: 198-9. PMID 16148917 DOI: 10.1038/437198A  0.532
2003 Wong WP, Heinrich V, Evans E. Exploring reaction pathways of single-molecule interactions through the manipulation and tracking of a potential-confined microsphere in three dimensions Mrs Proceedings. 790: 125-136. DOI: 10.1557/Proc-790-P5.1  0.59
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