| Year |
Citation |
Score |
| 2023 |
Alvarez-Calderon F, Kang BH, Kyrysyuk O, Zheng S, Wang H, Mathewson ND, Luoma AM, Ning X, Pyrdol J, Cao X, Suvà ML, Yuan GC, Wittrup KD, Wucherpfennig KW. Targeting of the CD161 Inhibitory Receptor Enhances T cell-mediated Immunity Against Hematological Malignancies. Blood. PMID 38153903 DOI: 10.1182/blood.2023022882 |
0.321 |
|
| 2022 |
Hagel KR, Arafeh R, Gang S, Arnoff TE, Larson RC, Doench JG, Mathewson ND, Wucherpfennig KW, Maus MV, Hahn WC. Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer Research. PMID 36548402 DOI: 10.1158/0008-5472.CAN-22-2245 |
0.315 |
|
| 2022 |
Kyrysyuk O, Wucherpfennig KW. Designing Cancer Immunotherapies That Engage T Cells and NK Cells. Annual Review of Immunology. PMID 36446137 DOI: 10.1146/annurev-immunol-101921-044122 |
0.364 |
|
| 2022 |
Badrinath S, Dellacherie MO, Li A, Zheng S, Zhang X, Sobral M, Pyrdol JW, Smith KL, Lu Y, Haag S, Ijaz H, Connor-Stroud F, Kaisho T, Dranoff G, Yuan GC, ... ... Wucherpfennig KW, et al. A vaccine targeting resistant tumours by dual T cell plus NK cell attack. Nature. PMID 35614223 DOI: 10.1038/s41586-022-04772-4 |
0.313 |
|
| 2022 |
Marx S, Godicelj A, Wucherpfennig KW. A Conceptual Framework for Inducing T Cell-Mediated Immunity Against Glioblastoma. Seminars in Immunopathology. PMID 35505129 DOI: 10.1007/s00281-022-00945-5 |
0.346 |
|
| 2021 |
Mathewson ND, Ashenberg O, Tirosh I, Gritsch S, Perez EM, Marx S, Jerby-Arnon L, Chanoch-Myers R, Hara T, Richman AR, Ito Y, Pyrdol J, Friedrich M, Schumann K, Poitras MJ, ... ... Wucherpfennig KW, et al. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis. Cell. PMID 33592174 DOI: 10.1016/j.cell.2021.01.022 |
0.356 |
|
| 2021 |
Cartwright ANR, Suo S, Badrinath S, Kumar S, Melms JC, Luoma A, Bagati A, Saadatpour A, Izar B, Yuan GC, Wucherpfennig KW. Immunosuppressive Myeloid Cells Induce Nitric Oxide-dependent DNA Damage and p53 Pathway Activation in CD8+ T cells. Cancer Immunology Research. PMID 33514509 DOI: 10.1158/2326-6066.CIR-20-0085 |
0.33 |
|
| 2020 |
Choi IK, Wang Z, Ke Q, Hong M, Paul DW, Fernandes SM, Hu Z, Stevens J, Guleria I, Kim HJ, Cantor H, Wucherpfennig KW, Brown JR, Ritz J, Zhang B. Mechanism of EBV inducing anti-tumour immunity and its therapeutic use. Nature. PMID 33361812 DOI: 10.1038/s41586-020-03075-w |
0.356 |
|
| 2020 |
Schoenfeld JD, Hanna GJ, Jo VY, Rawal B, Chen YH, Catalano PS, Lako A, Ciantra Z, Weirather JL, Criscitiello S, Luoma A, Chau N, Lorch J, Kass JI, Annino D, ... ... Wucherpfennig KW, et al. Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma: A Phase 2 Open-Label Randomized Clinical Trial. Jama Oncology. PMID 32852531 DOI: 10.1001/Jamaoncol.2020.2955 |
0.313 |
|
| 2020 |
Luoma AM, Suo S, Williams HL, Sharova T, Sullivan K, Manos M, Bowling P, Hodi FS, Rahma O, Sullivan RJ, Boland GM, Nowak JA, Dougan SK, Dougan M, Yuan GC, ... Wucherpfennig KW, et al. Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy. Cell. PMID 32603654 DOI: 10.1016/J.Cell.2020.06.001 |
0.458 |
|
| 2020 |
Tay RE, Olawoyin O, Cejas P, Xie Y, Meyer CA, Ito Y, Weng QY, Fisher DE, Long HW, Brown M, Kim HJ, Wucherpfennig KW. Correction: Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells. The Journal of Experimental Medicine. 217. PMID 32441763 DOI: 10.1084/Jem.2019145305152020C |
0.36 |
|
| 2020 |
Wang H, Sobral MC, Zhang DKY, Cartwright AN, Li AW, Dellacherie MO, Tringides CM, Koshy ST, Wucherpfennig KW, Mooney DJ. Metabolic labeling and targeted modulation of dendritic cells. Nature Materials. PMID 32424368 DOI: 10.1038/S41563-020-0680-1 |
0.373 |
|
| 2020 |
Tay RE, Olawoyin O, Cejas P, Xie Y, Meyer CA, Weng QY, Fisher DE, Long HW, Brown M, Kim HJ, Wucherpfennig KW. Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells. The Journal of Experimental Medicine. 217. PMID 32374402 DOI: 10.1084/Jem.20191453 |
0.429 |
|
| 2020 |
Ferrari de Andrade L, Kumar S, Luoma A, Ito Y, Alves da Silva PH, Pan D, Pyrdol JW, Yoon CH, Wucherpfennig KW. Inhibition of MICA and MICB Shedding Elicits NK cell-mediated Immunity against Tumors Resistant to Cytotoxic T cells. Cancer Immunology Research. PMID 32209637 DOI: 10.1158/2326-6066.Cir-19-0483 |
0.4 |
|
| 2020 |
Murata K, Jadhav U, Madha S, van Es J, Dean J, Cavazza A, Wucherpfennig K, Michor F, Clevers H, Shivdasani RA. Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. Cell Stem Cell. PMID 32084390 DOI: 10.1016/J.Stem.2019.12.011 |
0.32 |
|
| 2020 |
McCarthy N, Manieri E, Storm EE, Saadatpour A, Luoma AM, Kapoor VN, Madha S, Gaynor LT, Cox C, Keerthivasan S, Wucherpfennig K, Yuan GC, de Sauvage FJ, Turley SJ, Shivdasani RA. Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient. Cell Stem Cell. PMID 32084389 DOI: 10.1016/J.Stem.2020.01.008 |
0.322 |
|
| 2020 |
Jadhav U, Manieri E, Nalapareddy K, Madha S, Chakrabarti S, Wucherpfennig K, Barefoot M, Shivdasani RA. Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters. Molecular Cell. PMID 32027840 DOI: 10.1016/J.Molcel.2020.01.017 |
0.315 |
|
| 2019 |
Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, ... ... Wucherpfennig KW, et al. Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity. Cancer Research. PMID 31882401 DOI: 10.1158/0008-5472.Can-19-2330 |
0.342 |
|
| 2019 |
de Andrade LF, Lu Y, Luoma A, Ito Y, Pan D, Pyrdol JW, Yoon CH, Yuan GC, Wucherpfennig KW. Discovery of specialized NK cell populations infiltrating human melanoma metastases. Jci Insight. 4. PMID 31801909 DOI: 10.1172/Jci.Insight.133103 |
0.328 |
|
| 2019 |
Alspach E, Lussier DM, Miceli AP, Kizhvatov I, DuPage M, Luoma AM, Meng W, Lichti CF, Esaulova E, Vomund AN, Runci D, Ward JP, Gubin MM, Medrano RFV, Arthur CD, ... ... Wucherpfennig KW, et al. MHC-II neoantigens shape tumour immunity and response to immunotherapy. Nature. PMID 31645760 DOI: 10.1038/S41586-019-1671-8 |
0.403 |
|
| 2019 |
Kula T, Dezfulian MH, Wang CI, Abdelfattah NS, Hartman ZC, Wucherpfennig KW, Lyerly HK, Elledge SJ. T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes. Cell. 178: 1016-1028.e13. PMID 31398327 DOI: 10.1016/J.Cell.2019.07.009 |
0.463 |
|
| 2019 |
Janiszewska M, Tabassum DP, Castaño Z, Cristea S, Yamamoto KN, Kingston NL, Murphy KC, Shu S, Harper NW, Del Alcazar CG, Alečković M, Ekram MB, Cohen O, Kwak M, Qin Y, ... ... Wucherpfennig KW, et al. Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments. Nature Cell Biology. 21: 879-888. PMID 31263265 DOI: 10.1038/S41556-019-0346-X |
0.305 |
|
| 2019 |
Chan LL, Wucherpfennig K, De Andrade LF. Visualization and quantification of NK cell-mediated cytotoxicity over extended time periods by image cytometry. Journal of Immunological Methods. PMID 30951701 DOI: 10.1016/J.Jim.2019.04.001 |
0.337 |
|
| 2019 |
Hu X, Zhang J, Wang J, Fu J, Li T, Zheng X, Wang B, Gu S, Jiang P, Fan J, Ying X, Zhang J, Carroll MC, Wucherpfennig KW, Hacohen N, et al. Landscape of B cell immunity and related immune evasion in human cancers. Nature Genetics. PMID 30742113 DOI: 10.1038/S41588-018-0339-X |
0.354 |
|
| 2019 |
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS. Abstract B077: Signatures of T-cell dysfunction and exclusion predict cancer immunotherapy response Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B077 |
0.374 |
|
| 2019 |
Cartwright ANR, Jiang P, Saadatpour A, Yuan G, Liu SX, Wucherpfennig KW. Abstract A176: Overcoming CD8 T-cell suppression in the tumor microenvironment Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A176 |
0.388 |
|
| 2019 |
Pan D, Kobayashi A, Jiang P, Yuan G, Liu XS, Doench J, Qiu X, Rao P, Long H, Brown MA, Wucherpfennig KW, Andrade LFd, Tay RE, Luoma AM, Tsoucas D, et al. Abstract A146: Systematic discovery of immune regulatory mechanisms in tumor cells Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A146 |
0.404 |
|
| 2019 |
Jerby L, Shah P, Cuoco MS, Rodman C, Su M, Melms JM, Leeson R, Kanodia A, Mei S, Lin J, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Wucherpfennig KW, et al. Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A082 |
0.325 |
|
| 2019 |
Melms JC, Vallabhaneni S, Mills CE, Wucherpfennig K, Sorger PK, Izar B. Abstract B132: Inhibition of Haspin kinase to promote cell-intrinsic and extrinsic anticancer therapy Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-B132 |
0.3 |
|
| 2018 |
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, ... ... Wucherpfennig KW, et al. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. PMID 30568305 DOI: 10.1038/S41586-018-0792-9 |
0.395 |
|
| 2018 |
Formenti SC, Rudqvist NP, Golden E, Cooper B, Wennerberg E, Lhuillier C, Vanpouille-Box C, Friedman K, Ferrari de Andrade L, Wucherpfennig KW, Heguy A, Imai N, Gnjatic S, Emerson RO, Zhou XK, et al. Radiotherapy induces responses of lung cancer to CTLA-4 blockade. Nature Medicine. PMID 30397353 DOI: 10.1038/S41591-018-0232-2 |
0.328 |
|
| 2018 |
Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Wucherpfennig K, et al. A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell. 175: 984-997.e24. PMID 30388455 DOI: 10.1016/J.Cell.2018.09.006 |
0.342 |
|
| 2018 |
Cremasco V, Astarita JL, Grauel AL, Keerthivasan S, MacIsaac KD, Woodruff MC, Wu M, Spel L, Santoro S, Amoozgar Z, Laszewski T, Cruz-Migoni S, Knoblich K, Fletcher AL, LaFleur M, ... Wucherpfennig KW, et al. FAP delineates heterogeneous and functionally divergent stromal cells in immune-excluded breast tumors. Cancer Immunology Research. PMID 30266714 DOI: 10.1158/2326-6066.Cir-18-0098 |
0.349 |
|
| 2018 |
Ito Y, Ashenberg O, Pyrdol J, Luoma AM, Rozenblatt-Rosen O, Hofree M, Christian E, Ferrari de Andrade L, Tay RE, Teyton L, Regev A, Dougan SK, Wucherpfennig KW. Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity. The Journal of Experimental Medicine. PMID 30185635 DOI: 10.1084/Jem.20180300 |
0.389 |
|
| 2018 |
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nature Medicine. PMID 30127393 DOI: 10.1038/S41591-018-0136-1 |
0.368 |
|
| 2018 |
Kim YC, Zhang AH, Yoon J, Culp WE, Lees JR, Wucherpfennig KW, Scott DW. Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells. Journal of Autoimmunity. PMID 29857928 DOI: 10.1016/J.Jaut.2018.05.003 |
0.49 |
|
| 2018 |
Clark LE, Mahmutovic S, Raymond DD, Dilanyan T, Koma T, Manning JT, Shankar S, Levis SC, Briggiler AM, Enria DA, Wucherpfennig KW, Paessler S, Abraham J. Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nature Communications. 9: 1884. PMID 29760382 DOI: 10.1038/S41467-018-04271-Z |
0.319 |
|
| 2018 |
Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, ... ... Wucherpfennig KW, et al. Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.). 360: 331-335. PMID 29674595 DOI: 10.1126/Science.Aao4750 |
0.332 |
|
| 2018 |
Ferrari de Andrade L, Tay RE, Pan D, Luoma AM, Ito Y, Badrinath S, Tsoucas D, Franz B, May KF, Harvey CJ, Kobold S, Pyrdol JW, Yoon C, Yuan GC, Hodi FS, ... ... Wucherpfennig KW, et al. Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science (New York, N.Y.). 359: 1537-1542. PMID 29599246 DOI: 10.1126/Science.Aao0505 |
0.375 |
|
| 2018 |
Choi IK, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, Liu Y, Kim HJ, Ritz J, Cantor H, Rajewsky K, Wucherpfennig KW, Zhang B. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311309 DOI: 10.1073/Pnas.1713607115 |
0.43 |
|
| 2018 |
Pan D, Kobayashi A, Jiang P, Ferrari de Andrade L, Tay RE, Luoma A, Tsoucas D, Qiu X, Lim K, Rao P, Long HW, Yuan GC, Doench J, Brown M, Liu S, ... Wucherpfennig KW, et al. A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing. Science (New York, N.Y.). PMID 29301958 DOI: 10.1126/Science.Aao1710 |
0.416 |
|
| 2018 |
Keskin DB, Tirosh I, Anandappa A, Sun J, Mathewson ND, Shukla SA, Gjini E, Li S, Li L, Giobbie-Hurder A, Le PM, Hu Z, Zhang W, Olive O, McCluskey C, ... ... Wucherpfennig K, et al. Abstract 5631: Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma Cancer Research. 78: 5631-5631. DOI: 10.1158/1538-7445.Am2018-5631 |
0.332 |
|
| 2018 |
Li S, Sun J, Anandappa A, Spiro O, Leshchiner I, Datta K, Bao Y, Hu Z, Hacohen N, Mathewson ND, Tirosh I, Wucherpfennig K, Regev A, Suva M, Keskin DB, et al. Abstract 5387: Novel targeted single-cell TCR sequencing method used for analysis of a T cell infiltrate from a glioblastoma patient Cancer Research. 78: 5387-5387. DOI: 10.1158/1538-7445.Am2018-5387 |
0.435 |
|
| 2018 |
Reardon D, Keskin D, Tirosh I, Anandappa A, Mathewson N, Sun J, Shukla S, Gjini E, Li S, Giobbie-Hurder A, McCluskey C, Chiocca EA, Neuberg D, Wucherpfennig K, Suva M, et al. ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS Neuro-Oncology. 20: vi8-vi8. DOI: 10.1093/Neuonc/Noy148.027 |
0.318 |
|
| 2017 |
Schmid D, Park CG, Hartl CA, Subedi N, Cartwright AN, Puerto RB, Zheng Y, Maiarana J, Freeman GJ, Wucherpfennig KW, Irvine DJ, Goldberg MS. T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity. Nature Communications. 8: 1747. PMID 29170511 DOI: 10.1038/S41467-017-01830-8 |
0.341 |
|
| 2017 |
Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. Erratum: The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nature Immunology. 18: 1173. PMID 28926530 DOI: 10.1038/ni1017-1173d |
0.73 |
|
| 2017 |
Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, ... ... Wucherpfennig K, et al. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. PMID 28678778 DOI: 10.1038/Nature22991 |
0.391 |
|
| 2017 |
Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nature Immunology. PMID 28530712 DOI: 10.1038/Ni.3755 |
0.764 |
|
| 2017 |
Gagnon E, Connolly A, Dobbins J, Wucherpfennig KW. Studying Dynamic Plasma Membrane Binding of TCR-CD3 Chains During Immunological Synapse Formation Using Donor-Quenching FRET and FLIM-FRET. Methods in Molecular Biology (Clifton, N.J.). 1584: 259-289. PMID 28255707 DOI: 10.1007/978-1-4939-6881-7_16 |
0.434 |
|
| 2017 |
Van Elssen CH, Rashidian M, Vrbanac V, Wucherpfennig KW, El Habre Z, Sticht J, Freund C, Jacobsen J, Cragnolini J, Ingram J, Plaisier L, Spierings E, Tager AM, Ploegh H. Noninvasive imaging of human immune responses in a human xenograft model of graft-versus-host disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28209904 DOI: 10.2967/Jnumed.116.186007 |
0.5 |
|
| 2017 |
Verbeke CS, Gordo S, Schubert DA, Lewin SA, Desai RM, Dobbins J, Wucherpfennig KW, Mooney DJ. Multicomponent Injectable Hydrogels for Antigen-Specific Tolerogenic Immune Modulation. Advanced Healthcare Materials. PMID 28116870 DOI: 10.1002/Adhm.201600773 |
0.44 |
|
| 2016 |
Awad MM, Jones RE, Liu H, Lizotte PH, Ivanova EV, Kulkarni M, Herter-Sprie GS, Liao X, Santos AA, Bittinger MA, Keogh L, Koyama S, Almonte C, English JM, Barlow J, ... ... Wucherpfennig KW, et al. Cytotoxic T Cells in PD-L1-Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors. Cancer Immunology Research. PMID 27856426 DOI: 10.1158/2326-6066.Cir-16-0171 |
0.324 |
|
| 2016 |
Dobbins J, Gagnon E, Godec J, Pyrdol J, Vignali DA, Sharpe AH, Wucherpfennig KW. Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling. Science Signaling. 9: ra75. PMID 27460989 DOI: 10.1126/Scisignal.Aaf0626 |
0.376 |
|
| 2016 |
Wucherpfennig KW, Cartwright AN. Genetic screens to study the immune system in cancer. Current Opinion in Immunology. 41: 55-61. PMID 27309352 DOI: 10.1016/J.Coi.2016.05.007 |
0.303 |
|
| 2016 |
Cartwright AN, Tay RE, Wucherpfennig KW. Abstract A055: Systematic discovery of combinationimmunotherapy targets in vivo Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A055 |
0.35 |
|
| 2015 |
Bot A, Brewer JE, Eshhar Z, Frankel SR, Hickman E, Jungbluth AA, Morgan R, Peretz Y, Radvanyi L, Ramos CA, Robbins PF, Wucherpfennig KW. Target discovery for T cell therapy: next steps to advance Immunotherapies Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/S40425-015-0061-5 |
0.347 |
|
| 2014 |
Cremasco V, Woodruff MC, Onder L, Cupovic J, Nieves-Bonilla JM, Schildberg FA, Chang J, Cremasco F, Harvey CJ, Wucherpfennig K, Ludewig B, Carroll MC, Turley SJ. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nature Immunology. 15: 973-81. PMID 25151489 DOI: 10.1038/Ni.2965 |
0.417 |
|
| 2014 |
Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA. Membrane association of the CD3ε signaling domain is required for optimal T cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 193: 258-67. PMID 24899501 DOI: 10.4049/Jimmunol.1400322 |
0.449 |
|
| 2014 |
Birnbaum ME, Mendoza JL, Sethi DK, Dong S, Glanville J, Dobbins J, Ozkan E, Davis MM, Wucherpfennig KW, Garcia KC. Deconstructing the peptide-MHC specificity of T cell recognition. Cell. 157: 1073-87. PMID 24855945 DOI: 10.1016/J.Cell.2014.03.047 |
0.435 |
|
| 2014 |
Choudhuri K, Llodrá J, Roth EW, Tsai J, Gordo S, Wucherpfennig KW, Kam LC, Stokes DL, Dustin ML. Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse. Nature. 507: 118-23. PMID 24487619 DOI: 10.1038/Nature12951 |
0.475 |
|
| 2014 |
Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, ... ... Wucherpfennig KW, et al. In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature. 506: 52-7. PMID 24476824 DOI: 10.1038/Nature12988 |
0.562 |
|
| 2013 |
Sethi DK, Gordo S, Schubert DA, Wucherpfennig KW. Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop. Nature Communications. 4: 2623. PMID 24136005 DOI: 10.1038/Ncomms3623 |
0.457 |
|
| 2013 |
Harvey CJ, Wucherpfennig KW. Cracking the code of human T-cell immunity. Nature Biotechnology. 31: 609-10. PMID 23839145 DOI: 10.1038/Nbt.2626 |
0.406 |
|
| 2013 |
Pos W, Sethi DK, Wucherpfennig KW. Mechanisms of peptide repertoire selection by HLA-DM. Trends in Immunology. 34: 495-501. PMID 23835076 DOI: 10.1016/J.It.2013.06.002 |
0.351 |
|
| 2013 |
Torres AJ, Contento RL, Gordo S, Wucherpfennig KW, Love JC. Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells. Lab On a Chip. 13: 90-9. PMID 23070211 DOI: 10.1039/C2Lc40869D |
0.441 |
|
| 2012 |
Pos W, Sethi DK, Call MJ, Schulze MS, Anders AK, Pyrdol J, Wucherpfennig KW. Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection. Cell. 151: 1557-68. PMID 23260142 DOI: 10.1016/J.Cell.2012.11.025 |
0.352 |
|
| 2012 |
Gagnon E, Schubert DA, Gordo S, Chu HH, Wucherpfennig KW. Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain. The Journal of Experimental Medicine. 209: 2423-39. PMID 23166358 DOI: 10.1084/Jem.20120790 |
0.367 |
|
| 2012 |
Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, ... ... Wucherpfennig KW, et al. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity. 37: 276-89. PMID 22884313 DOI: 10.1016/J.Immuni.2012.05.022 |
0.359 |
|
| 2012 |
Angin M, King M, Altfeld M, Walker BD, Wucherpfennig KW, Addo MM. Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers. Aids (London, England). 26: 2112-5. PMID 22874519 DOI: 10.1097/Qad.0B013E328358Cc75 |
0.349 |
|
| 2012 |
Schubert DA, Gordo S, Sabatino JJ, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW. Self-reactive human CD4 T cell clones form unusual immunological synapses. The Journal of Experimental Medicine. 209: 335-52. PMID 22312112 DOI: 10.1084/Jem.20111485 |
0.47 |
|
| 2012 |
Schulze MS, Wucherpfennig KW. The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathway. Current Opinion in Immunology. 24: 105-11. PMID 22138314 DOI: 10.1016/J.Coi.2011.11.004 |
0.335 |
|
| 2012 |
May KF, Franz B, Harvey C, Hodi FS, Dranoff G, Wucherpfennig K. Isolation of human anti-MICA antibody from cancer patients responding to immunotherapies. Journal of Clinical Oncology. 30: 2502-2502. DOI: 10.1200/Jco.2012.30.15_Suppl.2502 |
0.318 |
|
| 2012 |
Angin M, Klarenbeek P, King M, Wucherpfennig K, Addo M. Identification of HIV-1-specific regulatory T cells using HLA-class-II tetramers Retrovirology. 9: 279. DOI: 10.1186/1742-4690-9-S2-P279 |
0.35 |
|
| 2012 |
Wucherpfennig K. Role of Disorder in T-Cell Signaling Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.023 |
0.467 |
|
| 2011 |
Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity. 35: 986-96. PMID 22177922 DOI: 10.1016/J.Immuni.2011.10.015 |
0.366 |
|
| 2011 |
Wen F, Sethi DK, Wucherpfennig KW, Zhao H. Cell surface display of functional human MHC class II proteins: yeast display versus insect cell display. Protein Engineering, Design & Selection : Peds. 24: 701-9. PMID 21752831 DOI: 10.1093/Protein/Gzr035 |
0.4 |
|
| 2011 |
Franz B, May KF, Dranoff G, Wucherpfennig K. Ex vivo characterization and isolation of rare memory B cells with antigen tetramers. Blood. 118: 348-57. PMID 21551230 DOI: 10.1182/Blood-2011-03-341917 |
0.332 |
|
| 2011 |
Lv H, Havari E, Pinto S, Gottumukkala RV, Cornivelli L, Raddassi K, Matsui T, Rosenzweig A, Bronson RT, Smith R, Fletcher AL, Turley SJ, Wucherpfennig K, Kyewski B, Lipes MA. Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans. The Journal of Clinical Investigation. 121: 1561-73. PMID 21436590 DOI: 10.1172/Jci44583 |
0.392 |
|
| 2011 |
Li S, Moffett HF, Lu J, Werner L, Zhang H, Ritz J, Neuberg D, Wucherpfennig KW, Brown JR, Novina CD. MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells. Plos One. 6: e16956. PMID 21408091 DOI: 10.1371/Journal.Pone.0016956 |
0.726 |
|
| 2011 |
Wucherpfennig KW, Sethi D. T cell receptor recognition of self and foreign antigens in the induction of autoimmunity. Seminars in Immunology. 23: 84-91. PMID 21306912 DOI: 10.1016/J.Smim.2011.01.007 |
0.428 |
|
| 2011 |
Sethi DK, Schubert DA, Anders AK, Heroux A, Bonsor DA, Thomas CP, Sundberg EJ, Pyrdol J, Wucherpfennig KW. A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. The Journal of Experimental Medicine. 208: 91-102. PMID 21199956 DOI: 10.1084/Jem.20100725 |
0.454 |
|
| 2011 |
Anders AK, Call MJ, Schulze MS, Fowler KD, Schubert DA, Seth NP, Sundberg EJ, Wucherpfennig KW. HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide. Nature Immunology. 12: 54-61. PMID 21131964 DOI: 10.1038/Ni.1967 |
0.318 |
|
| 2010 |
Wucherpfennig KW. The first structures of T cell receptors bound to peptide-MHC. Journal of Immunology (Baltimore, Md. : 1950). 185: 6391-3. PMID 21084667 DOI: 10.4049/Jimmunol.1090110 |
0.415 |
|
| 2010 |
Call ME, Wucherpfennig KW, Chou JJ. The structural basis for intramembrane assembly of an activating immunoreceptor complex. Nature Immunology. 11: 1023-9. PMID 20890284 DOI: 10.1038/Ni.1943 |
0.739 |
|
| 2010 |
Gagnon E, Xu C, Yang W, Chu HH, Call ME, Chou JJ, Wucherpfennig KW. Response multilayered control of T cell receptor phosphorylation. Cell. 142: 669-71. PMID 20813252 DOI: 10.1016/J.Cell.2010.08.019 |
0.707 |
|
| 2010 |
Wucherpfennig KW, Gagnon E, Call MJ, Huseby ES, Call ME. Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling. Cold Spring Harbor Perspectives in Biology. 2: a005140. PMID 20452950 DOI: 10.1101/Cshperspect.A005140 |
0.745 |
|
| 2010 |
Yi W, Seth NP, Martillotti T, Wucherpfennig KW, Sant'Angelo DB, Denzin LK. Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence. The Journal of Clinical Investigation. 120: 1324-36. PMID 20200448 DOI: 10.1172/Jci40220 |
0.39 |
|
| 2010 |
Schubert D, Gordo S, Vardhana S, Pyrdol J, Seth N, Raddassi K, Hafler D, Dustin M, Wucherpfennig K. Altered Synapse Formation by Self-reactive T Cells from MS Patients Clinical Immunology. 135: S75-S76. DOI: 10.1016/J.Clim.2010.03.227 |
0.531 |
|
| 2010 |
Sethi D, Schubert D, Wilbuer K, Wucherpfennig K. Structural Characterization of an Unusual Binding Mode of a Myelin-specific T Cell Receptor Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.216 |
0.431 |
|
| 2010 |
Gordo S, Schubert D, Vardhana S, Seth N, Pyrdol J, Raddassi K, Hafler D, Dustin M, Wucherpfennig K. Efficient Activation of Self-reactive T Cells from MS Patients with Altered Synapse Formation Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.031 |
0.532 |
|
| 2009 |
Wucherpfennig KW, Gagnon E. Positively selecting peptides: their job does not end in the thymus. Nature Immunology. 10: 1143-4. PMID 19841646 DOI: 10.1038/Ni1109-1143 |
0.368 |
|
| 2009 |
Wucherpfennig KW, Call MJ, Deng L, Mariuzza R. Structural alterations in peptide-MHC recognition by self-reactive T cell receptors. Current Opinion in Immunology. 21: 590-5. PMID 19699075 DOI: 10.1016/J.Coi.2009.07.008 |
0.457 |
|
| 2009 |
McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, ... ... Wucherpfennig KW, et al. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 183: 4067-76. PMID 19687098 DOI: 10.4049/Jimmunol.0801888 |
0.479 |
|
| 2009 |
Call MJ, Xing X, Cuny GD, Seth NP, Altmann DM, Fugger L, Krogsgaard M, Stein RL, Wucherpfennig KW. In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. Journal of Immunology (Baltimore, Md. : 1950). 182: 6342-52. PMID 19414787 DOI: 10.4049/Jimmunol.0803464 |
0.332 |
|
| 2009 |
Perone MJ, Bertera S, Shufesky WJ, Divito SJ, Montecalvo A, Mathers AR, Larregina AT, Pang M, Seth N, Wucherpfennig KW, Trucco M, Baum LG, Morelli AE. Suppression of autoimmune diabetes by soluble galectin-1. Journal of Immunology (Baltimore, Md. : 1950). 182: 2641-53. PMID 19234158 DOI: 10.4049/Jimmunol.0800839 |
0.403 |
|
| 2008 |
Xu C, Gagnon E, Call ME, Schnell JR, Schwieters CD, Carman CV, Chou JJ, Wucherpfennig KW. Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif. Cell. 135: 702-13. PMID 19013279 DOI: 10.1016/J.Cell.2008.09.044 |
0.713 |
|
| 2008 |
McLaughlin KA, Wucherpfennig KW. B cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseases. Advances in Immunology. 98: 121-49. PMID 18772005 DOI: 10.1016/S0065-2776(08)00404-5 |
0.415 |
|
| 2008 |
Bowen DG, Shoukry NH, Grakoui A, Fuller MJ, Cawthon AG, Dong C, Hasselschwert DL, Brasky KM, Freeman GJ, Seth NP, Wucherpfennig KW, Houghton M, Walker CM. Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection. Journal of Virology. 82: 5109-14. PMID 18337576 DOI: 10.1128/Jvi.00060-08 |
0.342 |
|
| 2008 |
Verginis P, McLaughlin KA, Wucherpfennig KW, von Boehmer H, Apostolou I. Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression. Proceedings of the National Academy of Sciences of the United States of America. 105: 3479-84. PMID 18299571 DOI: 10.1073/Pnas.0800149105 |
0.419 |
|
| 2008 |
McLaughlin K, Chitnis T, Banwell B, Bar-Or A, Kuhle J, Kappos L, Rostasy K, Pohl D, Wong S, Tavakoli N, Tenembaum S, Franz B, O'Connor K, Hafler D, Wucherpfennig K. F.14. Autoantibodies to Myelin Oligodendrocyte Glycoprotein in Pediatric MS Clinical Immunology. 127: S47-S48. DOI: 10.1016/J.Clim.2008.03.126 |
0.431 |
|
| 2007 |
Nose H, Kubota R, Seth NP, Goon PK, Tanaka Y, Izumo S, Usuku K, Ohara Y, Wucherpfennig KW, Bangham CR, Osame M, Saito M. Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide. The Journal of Infectious Diseases. 196: 1761-72. PMID 18190256 DOI: 10.1086/522966 |
0.474 |
|
| 2007 |
Call ME, Wucherpfennig KW. Common themes in the assembly and architecture of activating immune receptors. Nature Reviews. Immunology. 7: 841-50. PMID 17960150 DOI: 10.1038/Nri2186 |
0.725 |
|
| 2007 |
Grotenbreg GM, Nicholson MJ, Fowler KD, Wilbuer K, Octavio L, Yang M, Chakraborty AK, Ploegh HL, Wucherpfennig KW. Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association. The Journal of Biological Chemistry. 282: 21425-36. PMID 17525157 DOI: 10.1074/Jbc.M702844200 |
0.484 |
|
| 2007 |
Lu L, Ikizawa K, Hu D, Werneck MB, Wucherpfennig KW, Cantor H. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity. 26: 593-604. PMID 17509909 DOI: 10.1016/J.Immuni.2007.03.017 |
0.494 |
|
| 2007 |
Garibyan L, Lobito AA, Siegel RM, Call ME, Wucherpfennig KW, Geha RS. Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID). The Journal of Clinical Investigation. 117: 1550-7. PMID 17492055 DOI: 10.1172/Jci31023 |
0.67 |
|
| 2007 |
Wucherpfennig KW, Allen PM, Celada F, Cohen IR, De Boer R, Garcia KC, Goldstein B, Greenspan R, Hafler D, Hodgkin P, Huseby ES, Krakauer DC, Nemazee D, Perelson AS, Pinilla C, et al. Polyspecificity of T cell and B cell receptor recognition. Seminars in Immunology. 19: 216-24. PMID 17398114 DOI: 10.1016/J.Smim.2007.02.012 |
0.591 |
|
| 2007 |
Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nature Medicine. 13: 423-31. PMID 17384649 DOI: 10.1038/Nm1564 |
0.444 |
|
| 2007 |
Moza B, Varma AK, Buonpane RA, Zhu P, Herfst CA, Nicholson MJ, Wilbuer AK, Seth NP, Wucherpfennig KW, McCormick JK, Kranz DM, Sundberg EJ. Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. The Embo Journal. 26: 1187-97. PMID 17268555 DOI: 10.1038/Sj.Emboj.7601531 |
0.806 |
|
| 2007 |
O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, ... ... Wucherpfennig KW, et al. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature Medicine. 13: 211-7. PMID 17237795 DOI: 10.1038/Nm1488 |
0.514 |
|
| 2007 |
McLaughlin K, O'Connor K, Hafler D, Wucherpfennig K. Detection of autoantibodies with self-assembling radiolabeled antigen tetramers Nature Protocols. DOI: 10.1038/Nprot.2007.81 |
0.453 |
|
| 2007 |
Wucherpfennig KW. The structure and function of antigen receptors Seminars in Immunology. 19: 215. DOI: 10.1016/J.Smim.2007.04.004 |
0.346 |
|
| 2007 |
Korn T, Oukka M, Reddy J, Bettelli E, Awasthi A, Sobel R, Wucherpfennig K, Kuchroo V. Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation Clinical Immunology. 123: S152-S153. DOI: 10.1016/J.Clim.2007.03.073 |
0.445 |
|
| 2006 |
Call ME, Schnell JR, Xu C, Lutz RA, Chou JJ, Wucherpfennig KW. The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor. Cell. 127: 355-68. PMID 17055436 DOI: 10.1016/J.Cell.2006.08.044 |
0.732 |
|
| 2006 |
Xu C, Call ME, Wucherpfennig KW. A membrane-proximal tetracysteine motif contributes to assembly of CD3deltaepsilon and CD3gammaepsilon dimers with the T cell receptor. The Journal of Biological Chemistry. 281: 36977-84. PMID 17023417 DOI: 10.1074/Jbc.M607164200 |
0.718 |
|
| 2006 |
Ulsenheimer A, Lucas M, Seth NP, Tilman Gerlach J, Gruener NH, Loughry A, Pape GR, Wucherpfennig KW, Diepolder HM, Klenerman P. Transient immunological control during acute hepatitis C virus infection: ex vivo analysis of helper T-cell responses. Journal of Viral Hepatitis. 13: 708-14. PMID 16970603 DOI: 10.1111/J.1365-2893.2006.00747.X |
0.376 |
|
| 2006 |
Feng J, Call ME, Wucherpfennig KW. The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site. Plos Biology. 4: e142. PMID 16623599 DOI: 10.1371/Journal.Pbio.0040142 |
0.715 |
|
| 2006 |
Nicholson MJ, Moradi B, Seth NP, Xing X, Cuny GD, Stein RL, Wucherpfennig KW. Small molecules that enhance the catalytic efficiency of HLA-DM. Journal of Immunology (Baltimore, Md. : 1950). 176: 4208-20. PMID 16547258 DOI: 10.4049/Jimmunol.176.7.4208 |
0.37 |
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| 2005 |
Wucherpfennig KW. The structural interactions between T cell receptors and MHC-peptide complexes place physical limits on self-nonself discrimination. Current Topics in Microbiology and Immunology. 296: 19-37. PMID 16329190 DOI: 10.1007/3-540-30791-5_2 |
0.469 |
|
| 2005 |
Seth N, Kaufmann D, Lahey T, Rosenberg ES, Wucherpfennig KW. Expansion and contraction of HIV-specific CD4 T cells with short bursts of viremia, but physical loss of the majority of these cells with sustained viral replication. Journal of Immunology (Baltimore, Md. : 1950). 175: 6948-58. PMID 16272355 DOI: 10.4049/Jimmunol.175.10.6948 |
0.399 |
|
| 2005 |
Reddy J, Waldner H, Zhang X, Illes Z, Wucherpfennig KW, Sobel RA, Kuchroo VK. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 5591-5. PMID 16237044 DOI: 10.4049/Jimmunol.175.9.5591 |
0.379 |
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| 2005 |
Nicholson MJ, Hahn M, Wucherpfennig KW. Unusual features of self-peptide/MHC binding by autoimmune T cell receptors. Immunity. 23: 351-60. PMID 16226501 DOI: 10.1016/J.Immuni.2005.09.009 |
0.453 |
|
| 2005 |
O'Connor KC, Appel H, Bregoli L, Call ME, Catz I, Chan JA, Moore NH, Warren KG, Wong SJ, Hafler DA, Wucherpfennig KW. Antibodies from inflamed central nervous system tissue recognize myelin oligodendrocyte glycoprotein. Journal of Immunology (Baltimore, Md. : 1950). 175: 1974-82. PMID 16034142 DOI: 10.4049/Jimmunol.175.3.1974 |
0.706 |
|
| 2005 |
Garrity D, Call ME, Feng J, Wucherpfennig KW. The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure. Proceedings of the National Academy of Sciences of the United States of America. 102: 7641-6. PMID 15894612 DOI: 10.1073/Pnas.0502439102 |
0.756 |
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| 2005 |
Feng J, Garrity D, Call ME, Moffett H, Wucherpfennig KW. Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors. Immunity. 22: 427-38. PMID 15845448 DOI: 10.1016/J.Immuni.2005.02.005 |
0.792 |
|
| 2005 |
Hahn M, Nicholson MJ, Pyrdol J, Wucherpfennig KW. Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor. Nature Immunology. 6: 490-6. PMID 15821740 DOI: 10.1038/Ni1187 |
0.486 |
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| 2005 |
Call ME, Wucherpfennig KW. The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annual Review of Immunology. 23: 101-25. PMID 15771567 DOI: 10.1146/Annurev.Immunol.23.021704.115625 |
0.731 |
|
| 2004 |
Appel H, Kuon W, Kuhne M, Hülsmeyer M, Kollnberger S, Kuhlmann S, Weiss E, Zeitz M, Wucherpfennig K, Bowness P, Sieper J. The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes Journal of Immunology. 173: 6564-6573. PMID 15557146 DOI: 10.4049/Jimmunol.173.11.6564 |
0.362 |
|
| 2004 |
Reddy J, Illes Z, Zhang X, Encinas J, Pyrdol J, Nicholson L, Sobel RA, Wucherpfennig KW, Kuchroo VK. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15434-9. PMID 15492218 DOI: 10.1073/Pnas.0404444101 |
0.367 |
|
| 2004 |
Haining WN, Evans JW, Seth NP, Callaway GD, Wucherpfennig KW, Nadler LM, Guinan EC. Measuring T cell immunity to influenza vaccination in children after haemopoietic stem cell transplantation. British Journal of Haematology. 127: 322-5. PMID 15491293 DOI: 10.1111/J.1365-2141.2004.05204.X |
0.358 |
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| 2004 |
Ferlin WG, Mougneau E, Hugues S, Appel H, Jang MH, Cazareth J, Beaudoin L, Schricke C, Lehuen A, Wucherpfennig KW, Glaichenhaus N. Self-peptides that bind with low affinity to the diabetes-associated I-A(g7) molecule readily induce T cell tolerance in non-obese diabetic mice. European Journal of Immunology. 34: 2656-63. PMID 15368281 DOI: 10.1002/Eji.200425413 |
0.427 |
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| 2004 |
Mycko MP, Waldner H, Anderson DE, Bourcier KD, Wucherpfennig KW, Kuchroo VK, Hafler DA. Cross-reactive TCR responses to self antigens presented by different MHC class II molecules. Journal of Immunology (Baltimore, Md. : 1950). 173: 1689-98. PMID 15265898 DOI: 10.4049/Jimmunol.173.3.1689 |
0.617 |
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| 2004 |
Havari E, Lennon-Dumenil AM, Klein L, Neely D, Taylor JA, McInerney MF, Wucherpfennig KW, Lipes MA. Expression of the B7.1 costimulatory molecule on pancreatic beta cells abrogates the requirement for CD4 T cells in the development of type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 173: 787-96. PMID 15240665 DOI: 10.4049/Jimmunol.173.2.787 |
0.382 |
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| 2004 |
Call ME, Pyrdol J, Wucherpfennig KW. Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum. The Embo Journal. 23: 2348-57. PMID 15152191 DOI: 10.1038/Sj.Emboj.7600245 |
0.75 |
|
| 2004 |
Panoutsakopoulou V, Huster KM, McCarty N, Feinberg E, Wang R, Wucherpfennig KW, Cantor H. Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes. The Journal of Clinical Investigation. 113: 1218-24. PMID 15085201 DOI: 10.1172/Jci20772 |
0.469 |
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| 2004 |
Call ME, Wucherpfennig KW. Molecular mechanisms for the assembly of the T cell receptor-CD3 complex. Molecular Immunology. 40: 1295-305. PMID 15072848 DOI: 10.1016/J.Molimm.2003.11.017 |
0.735 |
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| 2004 |
Wucherpfennig KW. T cell receptor crossreactivity as a general property of T cell recognition. Molecular Immunology. 40: 1009-17. PMID 15036904 DOI: 10.1016/J.Molimm.2003.11.003 |
0.474 |
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| 2004 |
Taylor JA, Havari E, McInerney MF, Bronson R, Wucherpfennig KW, Lipes MA. A spontaneous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8. Journal of Immunology (Baltimore, Md. : 1950). 172: 2651-8. PMID 14764740 DOI: 10.4049/Jimmunol.172.4.2651 |
0.323 |
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| 2004 |
Wucherpfennig KW. Presentation of a self-peptide in two distinct conformations by a disease-associated HLA-B27 subtype. The Journal of Experimental Medicine. 199: 151-4. PMID 14734520 DOI: 10.1084/Jem.20032050 |
0.304 |
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| 2004 |
Haining WN, Evans J, Seth N, Callaway G, Wucherpfennig K, Nadler L, Guinan E. Rapid T Cell Response to Vaccination Can Occur without Antibody Response in Children Post HSCT. Blood. 104: 2235-2235. DOI: 10.1182/Blood.V104.11.2235.2235 |
0.4 |
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| 2004 |
Wucherpfennig KW. Implications of T Cell Receptor Crossreactivity for the Pathogenesis of Autoimmune Diseases Infection and Autoimmunity, 2nd Edition. 7-18. DOI: 10.1016/B978-044451271-0.50002-8 |
0.346 |
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| 2003 |
Wucherpfennig KW. MHC-linked susceptibility to type 1 diabetes: a structural perspective. Annals of the New York Academy of Sciences. 1005: 119-27. PMID 14679046 DOI: 10.1196/Annals.1288.013 |
0.369 |
|
| 2003 |
Berretta F, Butler RH, Diaz G, Sanarico N, Arroyo J, Fraziano M, Aichinger G, Wucherpfennig KW, Colizzi V, Saltini C, Amicosante M. Detailed analysis of the effects of Glu/Lys beta69 human leukocyte antigen-DP polymorphism on peptide-binding specificity. Tissue Antigens. 62: 459-71. PMID 14617029 DOI: 10.1046/J.1399-0039.2003.00131.X |
0.357 |
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| 2003 |
Jang MH, Seth NP, Wucherpfennig KW. Ex vivo analysis of thymic CD4 T cells in nonobese diabetic mice with tetramers generated from I-A(g7)/class II-associated invariant chain peptide precursors. Journal of Immunology (Baltimore, Md. : 1950). 171: 4175-86. PMID 14530340 DOI: 10.4049/Jimmunol.171.8.4175 |
0.429 |
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| 2003 |
Day CL, Seth NP, Lucas M, Appel H, Gauthier L, Lauer GM, Robbins GK, Szczepiorkowski ZM, Casson DR, Chung RT, Bell S, Harcourt G, Walker BD, Klenerman P, Wucherpfennig KW. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. The Journal of Clinical Investigation. 112: 831-42. PMID 12975468 DOI: 10.1172/Jci18509 |
0.441 |
|
| 2003 |
Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, et al. The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood. 102: 3287-94. PMID 12869499 DOI: 10.1182/Blood-2003-05-1374 |
0.423 |
|
| 2003 |
O'Connor KC, Chitnis T, Griffin DE, Piyasirisilp S, Bar-Or A, Khoury S, Wucherpfennig KW, Hafler DA. Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions. Journal of Neuroimmunology. 136: 140-8. PMID 12620653 DOI: 10.1016/S0165-5728(03)00002-X |
0.472 |
|
| 2003 |
Reddy J, Bettelli E, Nicholson L, Waldner H, Jang MH, Wucherpfennig KW, Kuchroo VK. Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers. Journal of Immunology (Baltimore, Md. : 1950). 170: 870-7. PMID 12517952 DOI: 10.4049/Jimmunol.170.2.870 |
0.466 |
|
| 2002 |
Call ME, Pyrdol J, Wiedmann M, Wucherpfennig KW. The organizing principle in the formation of the T cell receptor-CD3 complex. Cell. 111: 967-79. PMID 12507424 DOI: 10.1016/S0092-8674(02)01194-7 |
0.752 |
|
| 2002 |
Belmares MP, Busch R, Wucherpfennig KW, McConnell HM, Mellins ED. Structural factors contributing to DM susceptibility of MHC class II/peptide complexes. Journal of Immunology (Baltimore, Md. : 1950). 169: 5109-17. PMID 12391227 DOI: 10.4049/Jimmunol.169.9.5109 |
0.353 |
|
| 2002 |
Lang HL, Jacobsen H, Ikemizu S, Andersson C, Harlos K, Madsen L, Hjorth P, Sondergaard L, Svejgaard A, Wucherpfennig K, Stuart DI, Bell JI, Jones EY, Fugger L. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nature Immunology. 3: 940-3. PMID 12244309 DOI: 10.1038/Ni835 |
0.396 |
|
| 2002 |
von Bergwelt-Baildon MS, Vonderheide RH, Maecker B, Hirano N, Anderson KS, Butler MO, Xia Z, Zeng WY, Wucherpfennig KW, Nadler LM, Schultze JL. Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood. 99: 3319-25. PMID 11964299 DOI: 10.1182/Blood.V99.9.3319 |
0.422 |
|
| 2001 |
Wucherpfennig KW. Insights into autoimmunity gained from structural analysis of MHC-peptide complexes. Current Opinion in Immunology. 13: 650-6. PMID 11677085 DOI: 10.1016/S0952-7915(01)00274-6 |
0.4 |
|
| 2001 |
Wucherpfennig KW. Mechanisms for the induction of autoimmunity by infectious agents. The Journal of Clinical Investigation. 108: 1097-104. PMID 11602615 DOI: 10.1172/Jci14235 |
0.388 |
|
| 2001 |
Bourcier KD, Lim DG, Ding YH, Smith KJ, Wucherpfennig K, Hafler DA. Conserved CDR3 regions in T-cell receptor (TCR) CD8+ T cells that recognize the Tax11-19/HLA-A*0201 complex in a subject infected with human T-cell leukemia virus type 1: Relationship of T-cell fine specificity and major histocompatibility complex/peptide/TCR crystal structure Journal of Virology. 75: 9836-9843. PMID 11559817 DOI: 10.1128/Jvi.75.20.9836-9843.2001 |
0.616 |
|
| 2001 |
Panoutsakopoulou V, Sanchirico ME, Huster KM, Jansson M, Granucci F, Shim DJ, Wucherpfennig KW, Cantor H. Analysis of the relationship between viral infection and autoimmune disease. Immunity. 15: 137-47. PMID 11485745 DOI: 10.1016/S1074-7613(01)00172-8 |
0.373 |
|
| 2001 |
Wucherpfennig KW. Structural basis of molecular mimicry. Journal of Autoimmunity. 16: 293-302. PMID 11334495 DOI: 10.1006/Jaut.2000.0499 |
0.383 |
|
| 2001 |
Appel H, Seth NP, Gauthier L, Wucherpfennig KW. Anergy induction by dimeric TCR ligands. Journal of Immunology (Baltimore, Md. : 1950). 166: 5279-85. PMID 11290814 DOI: 10.4049/Jimmunol.166.8.5279 |
0.5 |
|
| 2000 |
Malherbe L, Filippi C, Julia V, Foucras G, Moro M, Appel H, Wucherpfennig K, Guéry J, Glaichenhaus N. Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major. Immunity. 13: 771-782. PMID 11163193 DOI: 10.1016/S1074-7613(00)00075-3 |
0.424 |
|
| 2000 |
Yu B, Gauthier L, Hausmann DH, Wucherpfennig KW. Binding of conserved islet peptides by human and murine MHC class II molecules associated with susceptibility to type I diabetes. European Journal of Immunology. 30: 2497-506. PMID 11009082 DOI: 10.1002/1521-4141(200009)30:9<2497::Aid-Immu2497>3.0.Co;2-J |
0.346 |
|
| 2000 |
Krogsgaard M, Wucherpfennig KW, Cannella B, Hansen BE, Svejgaard A, Pyrdol J, Ditzel H, Raine C, Engberg J, Fugger L, Canella B. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex. The Journal of Experimental Medicine. 191: 1395-412. PMID 10770805 DOI: 10.1084/Jem.191.8.1395 |
0.403 |
|
| 2000 |
Appel H, Gauthier L, Pyrdol J, Wucherpfennig KW. Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells. The Journal of Biological Chemistry. 275: 312-21. PMID 10617620 DOI: 10.1074/Jbc.275.1.312 |
0.49 |
|
| 1999 |
Madsen LS, Andersson EC, Jansson L, krogsgaard M, Andersen CB, Engberg J, Strominger JL, Svejgaard A, Hjorth JP, Holmdahl R, Wucherpfennig KW, Fugger L. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nature Genetics. 23: 343-7. PMID 10610182 DOI: 10.1038/15525 |
0.561 |
|
| 1999 |
Hausmann DH, Yu B, Hausmann S, Wucherpfennig KW. pH-dependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: rapid release of CLIP at an endosomal pH. The Journal of Experimental Medicine. 189: 1723-34. PMID 10359576 DOI: 10.1084/Jem.189.11.1723 |
0.331 |
|
| 1999 |
Fridkis-Hareli M, Neveu JM, Robinson RA, Lane WS, Gauthier L, Wucherpfennig KW, Sela M, Strominger JL. Binding motifs of copolymer 1 to multiple sclerosis- and rheumatoid arthritis-associated HLA-DR molecules. Journal of Immunology (Baltimore, Md. : 1950). 162: 4697-704. PMID 10202010 |
0.409 |
|
| 1998 |
Ufret-Vincenty RL, Quigley L, Tresser N, Pak SH, Gado A, Hausmann S, Wucherpfennig KW, Brocke S. In vivo survival of viral antigen-specific T cells that induce experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 188: 1725-38. PMID 9802984 DOI: 10.1084/Jem.188.9.1725 |
0.456 |
|
| 1998 |
Smith KJ, Pyrdol J, Gauthier L, Wiley DC, Wucherpfennig KW. Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein. The Journal of Experimental Medicine. 188: 1511-20. PMID 9782128 DOI: 10.1084/Jem.188.8.1511 |
0.413 |
|
| 1998 |
Gauthier L, Smith KJ, Pyrdol J, Kalandadze A, Strominger JL, Wiley DC, Wucherpfennig KW. Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 11828-33. PMID 9751750 DOI: 10.1073/Pnas.95.20.11828 |
0.57 |
|
| 1998 |
Liedtke W, Cannella B, Mazzaccaro RJ, Clements JM, Miller KM, Wucherpfennig KW, Gearing AJ, Raine CS. Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. Annals of Neurology. 44: 35-46. PMID 9667591 DOI: 10.1002/Ana.410440110 |
0.323 |
|
| 1998 |
Brocke S, Hausmann S, Steinman L, Wucherpfennig KW. Microbial peptides and superantigens in the pathogenesis of autoimmune diseases of the central nervous system. Seminars in Immunology. 10: 57-67. PMID 9529656 DOI: 10.1006/Smim.1997.0105 |
0.475 |
|
| 1998 |
Wucherpfennig K, Smith K, Pyrodol J, Gauthier L, Strominger J, Wiley D. Crystallization of the complex of HLA-DR2 with immunodominant myelin basic protein peptide Journal of Neuroimmunology. 90: 11. DOI: 10.1016/S0165-5728(98)91259-0 |
0.467 |
|
| 1997 |
Hausmann S, Wucherpfennig KW. Activation of autoreactive T cells by peptides from human pathogens. Current Opinion in Immunology. 9: 831-8. PMID 9492986 DOI: 10.1016/S0952-7915(97)80186-0 |
0.498 |
|
| 1997 |
Warren KG, Catz I, Wucherpfennig KW. Tolerance induction to myelin basic protein by intravenous synthetic peptides containing epitope P85 VVHFFKNIVTP96 in chronic progressive multiple sclerosis. Journal of the Neurological Sciences. 152: 31-8. PMID 9395124 DOI: 10.1016/S0022-510X(97)00130-5 |
0.371 |
|
| 1997 |
Wucherpfennig KW, Catz I, Hausmann S, Strominger JL, Steinman L, Warren KG. Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes. The Journal of Clinical Investigation. 100: 1114-22. PMID 9276728 DOI: 10.1172/Jci119622 |
0.611 |
|
| 1996 |
Kalandadze A, Galleno M, Foncerrada L, Strominger JL, Wucherpfennig KW. Expression of recombinant HLA-DR2 molecules. Replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the assembly and secretion of soluble DR alpha beta heterodimers. The Journal of Biological Chemistry. 271: 20156-62. PMID 8702739 DOI: 10.1074/Jbc.271.33.20156 |
0.592 |
|
| 1995 |
Wucherpfennig KW, Yu B, Bhol K, Monos DS, Argyris E, Karr RW, Ahmed AR, Strominger JL. Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris. Proceedings of the National Academy of Sciences of the United States of America. 92: 11935-9. PMID 8524878 DOI: 10.1073/Pnas.92.25.11935 |
0.548 |
|
| 1995 |
Wucherpfennig KW, Strominger JL. Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases. The Journal of Experimental Medicine. 181: 1597-601. PMID 7722439 DOI: 10.1084/Jem.181.5.1597 |
0.494 |
|
| 1995 |
Wucherpfennig KW, Hafler DA, Strominger JL. Structure of human T-cell receptors specific for an immunodominant myelin basic protein peptide: positioning of T-cell receptors on HLA-DR2/peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. 92: 8896-900. PMID 7568039 DOI: 10.1073/Pnas.92.19.8896 |
0.645 |
|
| 1995 |
Wucherpfennig KW, Hafler DA. A review of T-cell receptors in multiple sclerosis: clonal expansion and persistence of human T-cells specific for an immunodominant myelin basic protein peptide. Annals of the New York Academy of Sciences. 756: 241-58. PMID 7544075 DOI: 10.1111/J.1749-6632.1995.Tb44522.X |
0.607 |
|
| 1995 |
Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell. 80: 695-705. PMID 7534214 DOI: 10.1016/0092-8674(95)90348-8 |
0.604 |
|
| 1994 |
Wucherpfennig KW. Autoimmunity in the central nervous system: mechanisms of antigen presentation and recognition. Clinical Immunology and Immunopathology. 72: 293-306. PMID 8062444 DOI: 10.1006/Clin.1994.1145 |
0.431 |
|
| 1994 |
Chung S, Wucherpfennig KW, Friedman SM, Hafler DA, Strominger JL. Functional three-domain single-chain T-cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 91: 12654-8. PMID 7809095 DOI: 10.1073/Pnas.91.26.12654 |
0.633 |
|
| 1994 |
Wucherpfennig KW, Zhang J, Witek C, Matsui M, Modabber Y, Ota K, Hafler DA. Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. Journal of Immunology (Baltimore, Md. : 1950). 152: 5581-92. PMID 7514641 |
0.526 |
|
| 1994 |
Wucherpfennig KW, Sette A, Southwood S, Oseroff C, Matsui M, Strominger JL, Hafler DA. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. The Journal of Experimental Medicine. 179: 279-90. PMID 7505801 DOI: 10.1084/Jem.179.1.279 |
0.672 |
|
| 1994 |
Wucherpfennig KW, Strominger JL. Peptide independent assembly of HLA-DR2 molecules from subunits expressed in E. coli Journal of Neuroimmunology. 54: 206. DOI: 10.1016/0165-5728(94)90588-6 |
0.465 |
|
| 1993 |
Wucherpfennig KW, Liao YJ, Prendergast M, Prendergast J, Hafler DA, Strominger JL. Human fetal liver gamma/delta T cells predominantly use unusual rearrangements of the T cell receptor delta and gamma loci expressed on both CD4+CD8- and CD4-CD8- gamma/delta T cells. The Journal of Experimental Medicine. 177: 425-32. PMID 8093893 DOI: 10.1084/Jem.177.2.425 |
0.639 |
|
| 1992 |
Wucherpfennig KW, Höllsberg P, Richardson JH, Benjamin D, Hafler DA. T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones. Proceedings of the National Academy of Sciences of the United States of America. 89: 2110-4. PMID 1549569 DOI: 10.1073/Pnas.89.6.2110 |
0.606 |
|
| 1992 |
Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA. Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesions. Proceedings of the National Academy of Sciences of the United States of America. 89: 4588-92. PMID 1374907 DOI: 10.1073/Pnas.89.10.4588 |
0.584 |
|
| 1992 |
Höllsberg P, Wucherpfennig KW, Ausubel LJ, Calvo V, Bierer BE, Hafler DA. Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. Journal of Immunology (Baltimore, Md. : 1950). 148: 3256-63. PMID 1374452 |
0.502 |
|
| 1992 |
Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA. T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions. The Journal of Experimental Medicine. 175: 993-1002. PMID 1348083 DOI: 10.1084/Jem.175.4.993 |
0.515 |
|
| 1991 |
Lee SJ, Wucherpfennig KW, Brod SA, Benjamin D, Weiner HL, Hafler DA. Common T-cell receptor V beta usage in oligoclonal T lymphocytes derived from cerebrospinal fluid and blood of patients with multiple sclerosis. Annals of Neurology. 29: 33-40. PMID 1847614 DOI: 10.1002/Ana.410290109 |
0.697 |
|
| 1991 |
Lauer K, Hafler DA, Wucherpfennig KW, Brod SA, Weiner HL. T-cell receptor biology and multiple sclerosis [2] Annals of Neurology. 30: 623-624. PMID 1789690 |
0.364 |
|
| 1991 |
Hafler DA, Matsui M, Wucherpfennig KW, Ota K, Weiner HL. The potential of restricted T cell recognition of myelin basic protein epitopes in the therapy of multiple sclerosis. Annals of the New York Academy of Sciences. 636: 251-65. PMID 1724362 DOI: 10.1111/J.1749-6632.1991.Tb33456.X |
0.667 |
|
| 1991 |
Wucherpfennig KW, Weiner HL, Hafler DA. T-cell recognition of myelin basic protein. Immunology Today. 12: 277-82. PMID 1716903 DOI: 10.1016/0167-5699(91)90126-E |
0.649 |
|
| 1991 |
Balk SP, Ebert EC, Blumenthal RL, McDermott FV, Wucherpfennig KW, Landau SB, Blumberg RS. Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science (New York, N.Y.). 253: 1411-5. PMID 1716785 DOI: 10.1126/Science.1716785 |
0.45 |
|
| 1991 |
Höllsberg P, Wucherpfennig KW, Bierer BE, Hafler DA. HTLV-1 induced spontaneous T cell clonal proliferation is rapamycin sensitive Journal of Neuroimmunology. 35: 201. DOI: 10.1016/0165-5728(91)91225-2 |
0.555 |
|
| 1991 |
Wucherpfennig KW, Newcombe J, Cuzner L, Li H, Keddy C, Hafler DA. Analysis of αβ and γδ T cell receptors in multiple sclerosis plaques Journal of Neuroimmunology. 35: 28. DOI: 10.1016/0165-5728(91)90882-8 |
0.598 |
|
| 1991 |
Hafler DA, Wucherpfennig KW, Brod SA, Weiner HL. Reply Annals of Neurology. 30: 624-624. DOI: 10.1002/ana.410300422 |
0.388 |
|
| 1990 |
Wucherpfennig KW, Ota K, Endo N, Seidman JG, Rosenzweig A, Weiner HL, Hafler DA. Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein. Science (New York, N.Y.). 248: 1016-9. PMID 1693015 DOI: 10.1126/Science.1693015 |
0.677 |
|
| 1988 |
Schluesener HJ, Wucherpfennig KW, Weiner HL. Gene activation during experimental allergic encephalomyelitis. Cloning of new cDNAs. Annals of the New York Academy of Sciences. 540: 264-5. PMID 3207255 DOI: 10.1111/J.1749-6632.1988.Tb27071.X |
0.493 |
|
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