Yingzi Yang - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cheng C, Cong Q, Liu Y, Hu Y, Liang G, Dioneda KMM, Yang Y. Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with and expression. Science Advances. 9: eadf6927. PMID 37315133 DOI: 10.1126/sciadv.adf6927  0.355
2021 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y. loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/β-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34172578 DOI: 10.1073/pnas.2020100118  0.372
2020 Moore ER, Mathews OA, Yao Y, Yang Y. Prx1-expressing cells contributing to fracture repair require primary cilia for complete healing in mice. Bone. 115738. PMID 33188955 DOI: 10.1016/j.bone.2020.115738  0.337
2020 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, ... Yang Y, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-β-catenin. Elife. 9. PMID 32186512 DOI: 10.7554/Elife.52779  0.417
2020 Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, ... ... Yang Y, et al. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature Cell Biology. PMID 32015438 DOI: 10.1038/S41556-020-0463-6  0.419
2020 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, ... Yang Y, et al. Author response: Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin Elife. DOI: 10.7554/Elife.52779.Sa2  0.355
2020 Yang Y, Kim W, Wang X. Abstract IA11: Hippo signaling Is Intrinsically regulated during cell cycle progression Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-Ia11  0.506
2019 Cho YS, Li S, Wang X, Zhu J, Zhuo S, Han Y, Yue T, Yang Y, Jiang J. CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus. Genes & Development. PMID 31857346 DOI: 10.1101/Gad.333146.119  0.405
2019 Clara JA, Monge C, Yang Y, Takebe N. Targeting signalling pathways and the immune microenvironment of cancer stem cells - a clinical update. Nature Reviews. Clinical Oncology. PMID 31792354 DOI: 10.1038/S41571-019-0293-2  0.415
2019 Wickström SA, Yang Y. Editorial overview: Cell differentiation and development - wiring principles of transcriptional states, signaling networks and cell fate trajectories. Current Opinion in Cell Biology. PMID 31735435 DOI: 10.1016/J.Ceb.2019.10.002  0.4
2019 Deng Q, Li P, Che M, Liu J, Biswas S, Ma G, He L, Wei Z, Zhang Z, Yang Y, Liu H, Li B. Activation of Hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin. Elife. 8. PMID 31482846 DOI: 10.7554/Elife.50208  0.473
2019 Kim W, Cho YS, Wang X, Park O, Ma X, Kim H, Gan W, Jho EH, Cha B, Jeung YJ, Zhang L, Gao B, Wei W, Jiang J, Chung KS, ... Yang Y, et al. Hippo signaling is intrinsically regulated during cell cycle progression by APC/C. Proceedings of the National Academy of Sciences of the United States of America. PMID 31000600 DOI: 10.1073/Pnas.1821370116  0.471
2019 Cong Q, Xu R, Yang Y. Gα signaling in skeletal development, homeostasis and diseases. Current Topics in Developmental Biology. 133: 281-307. PMID 30902256 DOI: 10.1016/Bs.Ctdb.2018.11.019  0.511
2019 Deng Q, Li P, Che M, Liu J, Biswas S, Ma G, He L, Wei Z, Zhang Z, Yang Y, Liu H, Li B. Author response: Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin Elife. DOI: 10.7554/Elife.50208.028  0.45
2019 Yang Y. Decision letter: Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling Elife. DOI: 10.7554/Elife.47542.Sa1  0.37
2018 Xu R, Khan SK, Zhou T, Gao B, Zhou Y, Zhou X, Yang Y. Gα signaling controls intramembranous ossification during cranial bone development by regulating both Hedgehog and Wnt/β-catenin signaling. Bone Research. 6: 33. PMID 30479847 DOI: 10.1038/S41413-018-0034-7  0.499
2018 Jin Y, Cong Q, Gvozdenovic-Jeremic J, Hu J, Zhang Y, Terkeltaub R, Yang Y. inhibits ectopic joint calcification and maintains articular chondrocytes by repressing Hedgehog signaling. Development (Cambridge, England). PMID 30111653 DOI: 10.1242/Dev.164830  0.4
2018 Jiang Y, Feng D, Ma X, Fan S, Gao Y, Fu K, Wang Y, Sun J, Yao X, Liu C, Zhang H, Xu L, Liu A, Gonzalez FJ, Yang Y, et al. Pregnane X Receptor Regulates Liver Size and Liver Cell Fate via Yes-associated Protein Activation. Hepatology (Baltimore, Md.). PMID 30048004 DOI: 10.1002/Hep.30131  0.311
2018 Gao B, Ajima R, Yang W, Li C, Song H, Anderson MJ, Liu RR, Lewandoski MB, Yamaguchi TP, Yang Y. Coordinated directional outgrowth and pattern formation by integration of Wnt5a and Fgf signaling in planar cell polarity. Development (Cambridge, England). PMID 29615464 DOI: 10.1242/Dev.163824  0.51
2017 Zhao X, Deng P, Iglesias-Bartolome R, Amornphimoltham P, Steffen DJ, Jin Y, Molinolo AA, de Castro LF, Ovejero D, Yuan Q, Chen Q, Han X, Bai D, Taylor SS, Yang Y, et al. Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29282319 DOI: 10.1073/Pnas.1713710115  0.395
2017 Khan SK, Yadav PS, Elliott G, Hu DZ, Xu R, Yang Y. Induced Gnas(R201H) expression from the endogenous Gnas locus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158412 DOI: 10.1073/Pnas.1714313114  0.488
2017 Yang W, Garrett L, Feng D, Elliott G, Liu X, Wang N, Wong YM, Choi NT, Yang Y, Gao B. Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development. Cell Research. PMID 29056748 DOI: 10.1038/Cr.2017.127  0.43
2017 Kim W, Khan SK, Liu Y, Xu R, Park O, He Y, Cha B, Gao B, Yang Y. Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma. Gut. PMID 28866620 DOI: 10.1136/Gutjnl-2017-314061  0.322
2017 Xu R, Hu J, Zhou X, Yang Y. Heterotopic ossification: Mechanistic insights and clinical challenges. Bone. PMID 28855144 DOI: 10.1016/J.Bone.2017.08.025  0.305
2017 Xu J, Hao X, Yin MX, Lu Y, Jin Y, Xu J, Ge L, Wu W, Ho M, Yang Y, Zhao Y, Zhang L. Function of Nerfin-1 in preventing medulla neurons dedifferentiation requires its inhibition of Notch activity. Development (Cambridge, England). PMID 28242614 DOI: 10.1242/Dev.141341  0.321
2017 Greer YE, Gao B, Yang Y, Nussenzweig A, Rubin JS. Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1. Plos One. 12: e0170903. PMID 28125685 DOI: 10.1371/Journal.Pone.0170903  0.325
2016 Yuan J, Cha J, Deng W, Bartos A, Sun X, Ho HH, Borg JP, Yamaguchi TP, Yang Y, Dey SK. Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911818 DOI: 10.1073/Pnas.1614946113  0.357
2016 Kim W, Khan SK, Yang Y. Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation. Bmb Reports. PMID 27881216 DOI: 10.5483/Bmbrep.2017.50.1.196  0.449
2016 Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y. Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis. The Journal of Clinical Investigation. PMID 27869648 DOI: 10.1172/Jci88486  0.425
2015 Yang Y, Mlodzik M. Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt). Annual Review of Cell and Developmental Biology. 31: 623-646. PMID 26566118 DOI: 10.1146/Annurev-Cellbio-100814-125315  0.503
2015 Yang J, Andre P, Ye L, Yang YZ. The Hedgehog signalling pathway in bone formation. International Journal of Oral Science. 7: 73-9. PMID 26023726 DOI: 10.1038/Ijos.2015.14  0.503
2015 Andre P, Song H, Kim W, Kispert A, Yang Y. Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development (Cambridge, England). 142: 1516-27. PMID 25813538 DOI: 10.1242/Dev.119065  0.488
2015 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, et al. Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Developmental Biology. 398: 242-54. PMID 25527076 DOI: 10.1016/J.Ydbio.2014.12.007  0.409
2015 Greer YE, Gao B, Yang Y, Lipkowitz S, Rubin JS. Abstract 3024: Lack of CK1δ increases DNA damage and genomic instability due to defects in DNA repair and mitotic checkpoints Cancer Research. 75: 3024-3024. DOI: 10.1158/1538-7445.Am2015-3024  0.331
2014 Pryor SE, Massa V, Savery D, Andre P, Yang Y, Greene ND, Copp AJ. Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals. Development (Cambridge, England). 141: 3153-8. PMID 25038043 DOI: 10.1242/Dev.111427  0.423
2014 Boutin C, Labedan P, Dimidschstein J, Richard F, Cremer H, André P, Yang Y, Montcouquiol M, Goffinet AM, Tissir F. A dual role for planar cell polarity genes in ciliated cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E3129-38. PMID 25024228 DOI: 10.1073/Pnas.1404988111  0.418
2014 Malhotra D, Yang Y. Wnts' fashion statement: from body stature to dysplasia. Bonekey Reports. 3: 541. PMID 24991404 DOI: 10.1038/Bonekey.2014.36  0.504
2014 Greer YE, Gao B, Yang Y, Rubin JS. Abstract 1335: Lack of casein kinase 1 delta induces DNA damage, inhibition of mTORC1 signaling and nucleophagy Cancer Research. 74: 1335-1335. DOI: 10.1158/1538-7445.Am2014-1335  0.367
2013 Regard JB, Malhotra D, Gvozdenovic-Jeremic J, Josey M, Chen M, Weinstein LS, Lu J, Shore EM, Kaplan FS, Yang Y. Activation of hedgehog signaling by loss of GNAS causes heterotopic ossification Nature Medicine. 19: 1505-1512. PMID 24076664 DOI: 10.1038/Nm.3314  0.534
2013 Gao B, Yang Y. Planar cell polarity in vertebrate limb morphogenesis. Current Opinion in Genetics & Development. 23: 438-44. PMID 23747034 DOI: 10.1016/J.Gde.2013.05.003  0.428
2013 Andre P, Yang Y. Reply to Mazzeu: Human mutations in RYK might cause Robinow syndrome. The Journal of Biological Chemistry. 288: 2906. PMID 23472253 DOI: 10.1074/Jbc.L112.444539  0.323
2012 Regard JB, Zhong Z, Williams BO, Yang Y. Wnt signaling in bone development and disease: making stronger bone with Wnts. Cold Spring Harbor Perspectives in Biology. 4. PMID 23209148 DOI: 10.1101/Cshperspect.A007997  0.483
2012 Andre P, Wang Q, Wang N, Gao B, Schilit A, Halford MM, Stacker SA, Zhang X, Yang Y. The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl2. The Journal of Biological Chemistry. 287: 44518-25. PMID 23144463 DOI: 10.1074/Jbc.M112.414441  0.527
2012 Glasco DM, Sittaramane V, Bryant W, Fritzsch B, Sawant A, Paudyal A, Stewart M, Andre P, Cadete Vilhais-Neto G, Yang Y, Song MR, Murdoch JN, Chandrasekhar A. The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled. Developmental Biology. 369: 211-22. PMID 22771245 DOI: 10.1016/J.Ydbio.2012.06.021  0.309
2012 Yang Y. Wnt signaling in development and disease. Cell & Bioscience. 2: 14. PMID 22520685 DOI: 10.1186/2045-3701-2-14  0.521
2012 Zhu X, Zhu H, Zhang L, Huang S, Cao J, Ma G, Feng G, He L, Yang Y, Guo X. Wls-mediated Wnts differentially regulate distal limb patterning and tissue morphogenesis. Developmental Biology. 365: 328-38. PMID 22377357 DOI: 10.1016/J.Ydbio.2012.02.019  0.474
2011 Regard JB, Cherman N, Palmer D, Kuznetsov SA, Celi FS, Guettier JM, Chen M, Bhattacharyya N, Wess J, Coughlin SR, Weinstein LS, Collins MT, Robey PG, Yang Y. Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 108: 20101-6. PMID 22106277 DOI: 10.1073/Pnas.1114656108  0.522
2011 Hopyan S, Sharpe J, Yang Y. Budding behaviors: Growth of the limb as a model of morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 1054-62. PMID 21384474 DOI: 10.1002/Dvdy.22601  0.391
2011 Gao B, Song H, Bishop K, Elliot G, Garrett L, English MA, Andre P, Robinson J, Sood R, Minami Y, Economides AN, Yang Y. Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Developmental Cell. 20: 163-76. PMID 21316585 DOI: 10.1016/J.Devcel.2011.01.001  0.489
2011 Gildea DE, Luetkemeier ES, Bao X, Loftus SK, Mackem S, Yang Y, Pavan WJ, Biesecker LG. The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1596-605. PMID 21292980 DOI: 10.1096/Fj.10-169771  0.355
2010 Song H, Hu J, Chen W, Elliott G, Andre P, Gao B, Yang Y. Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature. 466: 378-82. PMID 20562861 DOI: 10.1038/Nature09129  0.326
2010 Song H, Mak KK, Topol L, Yun K, Hu J, Garrett L, Chen Y, Park O, Chang J, Simpson RM, Wang CY, Gao B, Jiang J, Yang Y. Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proceedings of the National Academy of Sciences of the United States of America. 107: 1431-6. PMID 20080598 DOI: 10.1073/Pnas.0911409107  0.384
2009 Yang Y. Skeletal morphogenesis during embryonic development. Critical Reviews in Eukaryotic Gene Expression. 19: 197-218. PMID 19883365 DOI: 10.1615/Critreveukargeneexpr.V19.I3.30  0.446
2009 Al-Qattan MM, Yang Y, Kozin SH. Embryology of the upper limb. The Journal of Hand Surgery. 34: 1340-50. PMID 19700076 DOI: 10.1016/J.Jhsa.2009.06.013  0.329
2009 Yang Y, Kozin SH. Cell signaling regulation of vertebrate limb growth and patterning. The Journal of Bone and Joint Surgery. American Volume. 91: 76-80. PMID 19571072 DOI: 10.2106/Jbjs.I.00079  0.515
2009 Guo X, Mak KK, Taketo MM, Yang Y. The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. Plos One. 4: e6067. PMID 19557172 DOI: 10.1371/Journal.Pone.0006067  0.503
2009 Nemeth MJ, Mak KK, Yang Y, Bodine DM. beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells. Stem Cells (Dayton, Ohio). 27: 1109-19. PMID 19415781 DOI: 10.1002/Stem.32  0.46
2009 Tzchori I, Day TF, Carolan PJ, Zhao Y, Wassif CA, Li L, Lewandoski M, Gorivodsky M, Love PE, Porter FD, Westphal H, Yang Y. LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth. Development (Cambridge, England). 136: 1375-85. PMID 19304889 DOI: 10.1242/Dev.026476  0.443
2009 Yang Y. Growth and patterning in the limb: signaling gradients make the decision. Science Signaling. 2: pe3. PMID 19141858 DOI: 10.1126/Scisignal.253Pe3  0.499
2009 Topol L, Chen W, Song H, Day TF, Yang Y. Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus. The Journal of Biological Chemistry. 284: 3323-33. PMID 19047045 DOI: 10.1074/Jbc.M808048200  0.394
2008 Mak KK, Bi Y, Wan C, Chuang PT, Clemens T, Young M, Yang Y. Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression. Developmental Cell. 14: 674-88. PMID 18477451 DOI: 10.1016/J.Devcel.2008.02.003  0.46
2008 Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y. Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development (Cambridge, England). 135: 1947-56. PMID 18434416 DOI: 10.1242/Dev.018044  0.53
2008 Day TF, Yang Y. Wnt and hedgehog signaling pathways in bone development. The Journal of Bone and Joint Surgery. American Volume. 90: 19-24. PMID 18292352 DOI: 10.2106/Jbjs.G.01174  0.554
2008 Regard JB, Yang Y. Hedgehog signaling in postnatal bone Ibms Bonekey. 5: 243-252. DOI: 10.1138/20080324  0.43
2008 Song H, Kispert A, Yang Y. Redundant function of Wnt5a and Wnt11 in somitogenesis and anteroposterior axis elongation Developmental Biology. 319: 584-585. DOI: 10.1016/J.Ydbio.2008.05.417  0.339
2007 Nemeth MJ, Topol L, Anderson SM, Yang Y, Bodine DM. Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15436-41. PMID 17881570 DOI: 10.1073/Pnas.0704747104  0.508
2007 Nemeth M, Yang Y, Bodine D. β-Catenin Expression in Bone Marrow Stromal Cells Is Required for Normal Proliferation and Differentiation of Primitive Hematopoietic Cells. Blood. 110: 608-608. DOI: 10.1182/Blood.V110.11.608.608  0.383
2006 Mak KK, Chen MH, Day TF, Chuang PT, Yang Y. Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development (Cambridge, England). 133: 3695-707. PMID 16936073 DOI: 10.1242/Dev.02546  0.518
2006 Nemeth M, Yang Y, Bodine D. Canonical and Non-Canonical Wnt Signaling Regulate the Balance between HSC Self-Renewal and Differentiation. Blood. 108: 862-862. DOI: 10.1182/Blood.V108.11.862.862  0.377
2005 Kobayashi T, Soegiarto DW, Yang Y, Lanske B, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. The Journal of Clinical Investigation. 115: 1734-42. PMID 15951842 DOI: 10.1172/Jci24397  0.391
2005 Day TF, Guo X, Garrett-Beal L, Yang Y. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Developmental Cell. 8: 739-50. PMID 15866164 DOI: 10.1016/J.Devcel.2005.03.016  0.46
2004 Guo X, Day TF, Jiang X, Garrett-Beal L, Topol L, Yang Y. Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation. Genes & Development. 18: 2404-17. PMID 15371327 DOI: 10.1101/Gad.1230704  0.428
2003 Yang Y. Wnts and wing: Wnt signaling in vertebrate limb development and musculoskeletal morphogenesis. Birth Defects Research. Part C, Embryo Today : Reviews. 69: 305-17. PMID 14745971 DOI: 10.1002/Bdrc.10026  0.532
2003 Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, Yang Y. Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. The Journal of Cell Biology. 162: 899-908. PMID 12952940 DOI: 10.1083/Jcb.200303158  0.406
2003 Yang Y, Topol L, Lee H, Wu J. Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Development (Cambridge, England). 130: 1003-15. PMID 12538525 DOI: 10.1242/Dev.00324  0.412
1995 Yang Y, Niswander L. Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell. 80: 939-47. PMID 7697724 DOI: 10.1016/0092-8674(95)90297-X  0.642
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