Alexander M. Klibanov - Publications

Affiliations: 
Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
biochemistry in non-aqueous media, stability and stabilization of pharmaceutical proteins, and enzymes as catalysts in organic syntheses
Website:
http://chemistry.mit.edu/people/klibanov-alexander

330 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cardoso JF, Perasoli FB, Almeida TC, Marques MBF, Toledo CR, Gil PO, Tavares HDS, Da Paz MC, Mussel WDN, Magalhães JT, Silva GND, da Silva-Cunha A, Granjeiro PA, Klibanov AM, da Silva GR. Vancomycin-loaded N,N-dodecyl,methyl-polyethylenimine nanoparticles coated with hyaluronic acid to treat bacterial endophthalmitis: Development, characterization, and ocular biocompatibility. International Journal of Biological Macromolecules. PMID 33310092 DOI: 10.1016/j.ijbiomac.2020.12.057  0.251
2020 Wang W, Zhang Y, Anzivino MJ, Bertram EH, Woznak J, Klibanov A, Dumont E, Wintermark M, Lee KS. Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry. Journal of Visualized Experiments : Jove. PMID 33044450 DOI: 10.3791/61271  0.202
2019 Varfolomeyev SD, Klibanov AM, Martinek K, Berezin IV. Light-initiated enzymic activity caused by photostereoisomerization of cis-4-nitrocinnamoyl-alpha-chymotrypsin. Febs Letters. 15: 118-120. PMID 11945826 DOI: 10.1016/0014-5793(71)80036-4  0.675
2017 Larson AM, Weight AK, Love K, Bonificio A, Wescott CR, Klibanov AM. Bulky Polar Additives That Greatly Reduce the Viscosity of Concentrated Solutions of Therapeutic Monoclonal Antibodies. Journal of Pharmaceutical Sciences. PMID 28137697 DOI: 10.1016/J.Xphs.2017.01.018  0.363
2017 Kumar A, Klibanov AM. Viscosity-Reducing Bulky-Salt Excipients Prevent Gelation of Protein, but Not Carbohydrate, Solutions. Applied Biochemistry and Biotechnology. PMID 28116573 DOI: 10.1007/S12010-017-2413-8  0.414
2016 Weikart CM, Klibanov AM, Breeland AP, Taha AH, Maurer BR, Martin SP. Plasma-Treated Microplates with Enhanced Protein Recoveries and Minimized Extractables. Journal of Laboratory Automation. PMID 27651466 DOI: 10.1177/2211068216666258  0.372
2016 Rocha SM, Saraiva T, Cristóvão AC, Ferreira R, Santos T, Esteves M, Saraiva C, Je G, Cortes L, Valero J, Alves G, Klibanov A, Kim YS, Bernardino L. Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation. Journal of Neuroinflammation. 13: 137. PMID 27260166 DOI: 10.1186/S12974-016-0600-0  0.215
2015 Elkin I, Weight AK, Klibanov AM. Markedly Lowering the Viscosity of Aqueous Solutions of DNA by Additives. International Journal of Pharmaceutics. PMID 26260229 DOI: 10.1016/J.Ijpharm.2015.08.019  0.397
2015 Su E, Klibanov AM. Low-Transition-Temperature Mixtures (LTTMs) for Dissolving Proteins and for Drug Formulation. Applied Biochemistry and Biotechnology. PMID 26239446 DOI: 10.1007/S12010-015-1777-X  0.41
2015 Liu H, Elkin I, Chen J, Klibanov AM. Why do some immobilized N-alkylated polyethylenimines far surpass others in inactivating influenza viruses? Biomacromolecules. 16: 351-6. PMID 25486335 DOI: 10.1021/Bm5015427  0.41
2015 Zhu A, Liu HK, Long F, Su E, Klibanov AM. Inactivation of bacteria by electric current in the presence of carbon nanotubes embedded within a polymeric membrane. Applied Biochemistry and Biotechnology. 175: 666-76. PMID 25342266 DOI: 10.1007/S12010-014-1318-Z  0.351
2015 Liu H, Elkin I, Chen J, Klibanov AM. Why do some immobilized N-Alkylated polyethylenimines far surpass others in inactivating influenza viruses? Biomacromolecules. 16: 351-356. DOI: 10.1021/bm5015427  0.269
2015 Lu C, Su EZ, Wei DZ, Klibanov AM. The applications of deep eutectic solvents in biocatalysis Journal of Molecular Catalysis. 29: 390-401.  0.255
2014 Liu H, Kim Y, Mello K, Lovaasen J, Shah A, Rice N, Yim JH, Pappas D, Klibanov AM. Aerosol-assisted plasma deposition of hydrophobic polycations makes surfaces highly antimicrobial. Applied Biochemistry and Biotechnology. 172: 1254-64. PMID 24158590 DOI: 10.1007/S12010-013-0593-4  0.377
2014 Weight AK, Belser JA, Tumpey TM, Chen J, Klibanov AM. Zanamivir conjugated to poly-L-glutamine is much more active against influenza viruses in mice and ferrets than the drug itself. Pharmaceutical Research. 31: 466-74. PMID 24065587 DOI: 10.1007/S11095-013-1175-4  0.394
2014 Zhu A, Liu HK, Long F, Su E, Klibanov AM. Inactivation of Bacteria by Electric Current in the Presence of Carbon Nanotubes Embedded Within a Polymeric Membrane Applied Biochemistry and Biotechnology. 175: 666-676. DOI: 10.1007/s12010-014-1318-z  0.208
2013 Zale SE, Klibanov AM. Application of immobilized hydrogenase to h2 storage in concentrated solutions of methyl viologen. Applied Biochemistry and Biotechnology. 7: 317-23. PMID 24234361 DOI: 10.1007/Bf02798317  0.368
2013 Klibanov AM, Barta TE. Protection of immobilized sulfhydryl groups against autooxidation by alterations in their microenvironment. Applied Biochemistry and Biotechnology. 6: 201-6. PMID 24233881 DOI: 10.1007/Bf02780798  0.376
2013 Schlesinger D, Benedict S, Diederich C, Gedroyc W, Klibanov A, Larner J. MR-guided focused ultrasound surgery, present and future Medical Physics. 40. PMID 23927296 DOI: 10.1118/1.4811136  0.196
2013 Larson AM, Chen J, Klibanov AM. Conjugation to polymeric chains of influenza drugs targeting M2 ion channels partially restores inhibition of drug-resistant mutants. Journal of Pharmaceutical Sciences. 102: 2450-9. PMID 23832466 DOI: 10.1002/Jps.23644  0.358
2013 Tandon A, Sharma A, Rodier JT, Klibanov AM, Rieger FG, Mohan RR. BMP7 gene transfer via gold nanoparticles into stroma inhibits corneal fibrosis in vivo. Plos One. 8: e66434. PMID 23799103 DOI: 10.1371/Journal.Pone.0066434  0.345
2013 Larson AM, Klibanov AM. Biocidal packaging for pharmaceuticals, foods, and other perishables. Annual Review of Chemical and Biomolecular Engineering. 4: 171-86. PMID 23745746 DOI: 10.1146/Annurev-Chembioeng-061312-103253  0.345
2013 Srinivasan C, Weight AK, Bussemer T, Klibanov AM. Non-aqueous suspensions of antibodies are much less viscous than equally concentrated aqueous solutions. Pharmaceutical Research. 30: 1749-57. PMID 23543302 DOI: 10.1007/S11095-013-1017-4  0.39
2013 Gerrard SE, Larson AM, Klibanov AM, Slater NK, Hanson CV, Abrams BF, Morris MK. Reducing infectivity of HIV upon exposure to surfaces coated with N,N-dodecyl, methyl-polyethylenimine. Biotechnology and Bioengineering. 110: 2058-62. PMID 23436242 DOI: 10.1002/Bit.24867  0.382
2013 Park D, Larson AM, Klibanov AM, Wang Y. Antiviral and antibacterial polyurethanes of various modalities. Applied Biochemistry and Biotechnology. 169: 1134-46. PMID 23306899 DOI: 10.1007/S12010-012-9999-7  0.419
2013 Larson AM, Oh HS, Knipe DM, Klibanov AM. Decreasing herpes simplex viral infectivity in solution by surface-immobilized and suspended N,N-dodecyl,methyl-polyethylenimine. Pharmaceutical Research. 30: 25-31. PMID 22798261 DOI: 10.1007/S11095-012-0825-2  0.399
2012 Lee CM, Weight AK, Haldar J, Wang L, Klibanov AM, Chen J. Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 20385-90. PMID 23185023 DOI: 10.1073/Pnas.1219155109  0.622
2012 Sharma A, Rodier JT, Tandon A, Klibanov AM, Mohan RR. Attenuation of corneal myofibroblast development through nanoparticle-mediated soluble transforming growth factor-β type II receptor (sTGFβRII) gene transfer. Molecular Vision. 18: 2598-607. PMID 23112572  0.278
2012 Grant EV, Thomas M, Fortune J, Klibanov AM, Letvin NL. Enhancement of plasmid DNA immunogenicity with linear polyethylenimine. European Journal of Immunology. 42: 2937-48. PMID 22886924 DOI: 10.1002/Eji.201242410  0.745
2012 Larson AM, Wang H, Cao Y, Jiang T, Chen J, Klibanov AM. Conjugating drug candidates to polymeric chains does not necessarily enhance anti-influenza activity. Journal of Pharmaceutical Sciences. 101: 3896-905. PMID 22786697 DOI: 10.1002/Jps.23253  0.382
2012 Guo Z, Chen A, Nassar RA, Helk B, Mueller C, Tang Y, Gupta K, Klibanov AM. Structure-activity relationship for hydrophobic salts as viscosity-lowering excipients for concentrated solutions of monoclonal antibodies. Pharmaceutical Research. 29: 3102-9. PMID 22692671 DOI: 10.1007/S11095-012-0802-9  0.386
2012 Wong SY, Han L, Timachova K, Veselinovic J, Hyder MN, Ortiz C, Klibanov AM, Hammond PT. Drastically lowered protein adsorption on microbicidal hydrophobic/hydrophilic polyelectrolyte multilayers. Biomacromolecules. 13: 719-26. PMID 22300304 DOI: 10.1021/Bm201637E  0.512
2012 Nassar RA, Browne EP, Chen J, Klibanov AM. Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin. Biotechnology Letters. 34: 853-6. PMID 22207147 DOI: 10.1007/S10529-011-0840-0  0.346
2012 Schaer TP, Stewart S, Hsu BB, Klibanov AM. Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection. Biomaterials. 33: 1245-54. PMID 22082621 DOI: 10.1016/J.Biomaterials.2011.10.038  0.738
2012 Chopineau J, McCafferty FD, Therisod M, Klibanov AM. Production of biosurfactants from sugar alcohols and vegetable oils catalyzed by lipases in a nonaqueous medium. Biotechnology and Bioengineering. 31: 208-14. PMID 18584594 DOI: 10.1002/Bit.260310305  0.346
2012 Kazandjian RZ, Dordick JS, Klibanov AM. Enzymatic analyses in organic solvents. Biotechnology and Bioengineering. 28: 417-21. PMID 18555343 DOI: 10.1002/Bit.260280315  0.413
2012 Dropsy EP, Klibanov AM. Cholinesterase-catalyzed resolution of D,L-carnitine. Biotechnology and Bioengineering. 26: 911-5. PMID 18553477 DOI: 10.1002/Bit.260260815  0.339
2012 Cambou B, Klibanov AM. Comparison of different strategies for the lipase-catalyzed preparative resolution of racemic acids and alcohols: Asymmetric hydrolysis, esterification, and transesterification. Biotechnology and Bioengineering. 26: 1449-54. PMID 18551676 DOI: 10.1002/Bit.260261209  0.378
2011 Behlau I, Mukherjee K, Todani A, Tisdale AS, Cade F, Wang L, Leonard EM, Zakka FR, Gilmore MS, Jakobiec FA, Dohlman CH, Klibanov AM. Biocompatibility and biofilm inhibition of N,N-hexyl,methyl-polyethylenimine bonded to Boston Keratoprosthesis materials. Biomaterials. 32: 8783-96. PMID 21903257 DOI: 10.1016/J.Biomaterials.2011.08.010  0.367
2011 Onnis-Hayden A, Hsu BB, Klibanov AM, Gu AZ. An antimicrobial polycationic sand filter for water disinfection. Water Science and Technology : a Journal of the International Association On Water Pollution Research. 63: 1997-2003. PMID 21902041 DOI: 10.2166/Wst.2011.440  0.734
2011 Faustino JV, Wang X, Johnson CE, Klibanov A, Derugin N, Wendland MF, Vexler ZS. Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12992-3001. PMID 21900578 DOI: 10.1523/JNEUROSCI.2102-11.2011  0.205
2011 Long F, Gao C, Shi HC, He M, Zhu AN, Klibanov AM, Gu AZ. Reusable evanescent wave DNA biosensor for rapid, highly sensitive, and selective detection of mercury ions. Biosensors & Bioelectronics. 26: 4018-23. PMID 21550227 DOI: 10.1016/J.Bios.2011.03.022  0.246
2011 Fortune JA, Novobrantseva TI, Klibanov AM. Highly effective gene transfection in vivo by alkylated polyethylenimine. Journal of Drug Delivery. 2011: 204058. PMID 21490747 DOI: 10.1155/2011/204058  0.392
2011 Sharma A, Tandon A, Tovey JC, Gupta R, Robertson JD, Fortune JA, Klibanov AM, Cowden JW, Rieger FG, Mohan RR. Polyethylenimine-conjugated gold nanoparticles: Gene transfer potential and low toxicity in the cornea. Nanomedicine : Nanotechnology, Biology, and Medicine. 7: 505-13. PMID 21272669 DOI: 10.1016/J.Nano.2011.01.006  0.358
2011 Du W, Klibanov AM. Hydrophobic salts markedly diminish viscosity of concentrated protein solutions. Biotechnology and Bioengineering. 108: 632-6. PMID 21246510 DOI: 10.1002/Bit.22983  0.397
2011 Hsu BB, Yinn Wong S, Hammond PT, Chen J, Klibanov AM. Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations. Proceedings of the National Academy of Sciences of the United States of America. 108: 61-6. PMID 21173278 DOI: 10.1073/Pnas.1017012108  0.78
2011 Hsu BB, Klibanov AM. Light-activated covalent coating of cotton with bactericidal hydrophobic polycations. Biomacromolecules. 12: 6-9. PMID 21128596 DOI: 10.1021/Bm100934C  0.752
2011 Larson AM, Hsu BB, Rautaray D, Haldar J, Chen J, Klibanov AM. Hydrophobic polycationic coatings disinfect poliovirus and rotavirus solutions. Biotechnology and Bioengineering. 108: 720-3. PMID 20967804 DOI: 10.1002/Bit.22967  0.77
2011 Hsu BB, Ouyang J, Wong SY, Hammond PT, Klibanov AM. On structural damage incurred by bacteria upon exposure to hydrophobic polycationic coatings. Biotechnology Letters. 33: 411-6. PMID 20882318 DOI: 10.1007/S10529-010-0419-1  0.775
2011 Weight AK, Haldar J, Alvarez de Cienfuegos L, Gubareva LV, Tumpey TM, Chen J, Klibanov AM. Attaching zanamivir to a polymer markedly enhances its activity against drug-resistant strains of influenza a virus. Journal of Pharmaceutical Sciences. 100: 831-5. PMID 20740680 DOI: 10.1002/Jps.22338  0.758
2010 Wong SY, Moskowitz JS, Veselinovic J, Rosario RA, Timachova K, Blaisse MR, Fuller RC, Klibanov AM, Hammond PT. Dual functional polyelectrolyte multilayer coatings for implants: permanent microbicidal base with controlled release of therapeutic agents. Journal of the American Chemical Society. 132: 17840-8. PMID 21105659 DOI: 10.1021/Ja106288C  0.497
2010 Birukova AA, Xing J, Fu P, Yakubov B, Dubrovskyi O, Fortune JA, Klibanov AM, Birukov KG. Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L652-63. PMID 20729389 DOI: 10.1152/Ajplung.00202.2009  0.33
2010 Fortune JA, Wu BI, Klibanov AM. Radio frequency radiation causes no nonthermal damage in enzymes and living cells. Biotechnology Progress. 26: 1772-6. PMID 20572294 DOI: 10.1002/Btpr.462  0.39
2010 Wong SY, Li Q, Veselinovic J, Kim BS, Klibanov AM, Hammond PT. Bactericidal and virucidal ultrathin films assembled layer by layer from polycationic N-alkylated polyethylenimines and polyanions. Biomaterials. 31: 4079-87. PMID 20163855 DOI: 10.1016/J.Biomaterials.2010.01.119  0.508
2010 Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 4004-9. PMID 20142500 DOI: 10.1073/Pnas.0910781107  0.387
2010 Haldar J, Alvarez de Cienfuegos L, Tumpey TM, Gubareva LV, Chen J, Klibanov AM. Bifunctional polymeric inhibitors of human influenza A viruses. Pharmaceutical Research. 27: 259-63. PMID 20013036 DOI: 10.1007/S11095-009-0013-1  0.764
2010 Barzana E, Karel M, Klibanov AM. Enzymatic oxidation of ethanol in the gaseous phase. Biotechnology and Bioengineering. 34: 1178-85. PMID 18588215 DOI: 10.1002/Bit.260340908  0.404
2010 Maneepun S, Klibanov AM. Stabilization of microbiol protease against autolysis using acylation with dicarboxylic acid anhydrides. Biotechnology and Bioengineering. 24: 483-6. PMID 18546315 DOI: 10.1002/Bit.260240216  0.358
2010 Klibanov AM, Tu TM, Scott KP. Peroxidase-catalyzed removal of phenols from coal-conversion waste waters. Science (New York, N.Y.). 221: 259-61. PMID 17815191 DOI: 10.1126/Science.221.4607.259-A  0.391
2010 Klibanov AM. Immobilized enzymes and cells as practical catalysts. Science (New York, N.Y.). 219: 722-7. PMID 17814033 DOI: 10.1126/Science.219.4585.722  0.435
2010 Dordick JS, Marletta MA, Klibanov AM. Peroxidases depolymerize lignin in organic media but not in water. Proceedings of the National Academy of Sciences of the United States of America. 83: 6255-7. PMID 16593748 DOI: 10.1073/Pnas.83.17.6255  0.427
2010 Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution (Proceedings of the National Academy of Sciences of the United States of America (2010) 107 (4004-4009) DOI: 10.1073/pnas.0910781107) Proceedings of the National Academy of Sciences of the United States of America. 107: 6560. DOI: 10.1073/pnas.1002891107  0.19
2009 Xuan JW, Bygrave M, Valiyeva F, Moussa M, Izawa JI, Bauman GS, Klibanov A, Wang F, Greenberg NM, Fenster A. Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer model. Molecular Imaging. 8: 209-20. PMID 19728975 DOI: 10.2310/7290.2009.00020  0.201
2009 Antipov E, Cho AE, Klibanov AM. How a single-point mutation in horseradish peroxidase markedly enhances enantioselectivity. Journal of the American Chemical Society. 131: 11155-60. PMID 19610634 DOI: 10.1021/Ja903482U  0.414
2009 Singleton PA, Chatchavalvanich S, Fu P, Xing J, Birukova AA, Fortune JA, Klibanov AM, Garcia JG, Birukov KG. Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids. Circulation Research. 104: 978-86. PMID 19286607 DOI: 10.1161/Circresaha.108.193367  0.345
2009 Visuri K, Klibanov AM. Enzymatic production of high fructose corn syrup (HFCS) containing 55% fructose in aqueous ethanol. Biotechnology and Bioengineering. 30: 917-20. PMID 18581528 DOI: 10.1002/Bit.260300715  0.342
2009 Shaw JF, Klibanov AM. Preparation of various glucose esters via lipase-catalyzed hydrolysis of glucose pentaacetate. Biotechnology and Bioengineering. 29: 648-51. PMID 18576497 DOI: 10.1002/Bit.260290515  0.352
2009 Zale SE, Klibanov AM. On the role of reversible denaturation (unfolding) in the irreversible thermal inactivation of enzymes. Biotechnology and Bioengineering. 25: 2221-30. PMID 18574817 DOI: 10.1002/Bit.260250908  0.45
2009 Scollar MP, Sigal G, Klibanov AM. Preparative resolution of D,L-threonine catalyzed by immobilized phosphatase. Biotechnology and Bioengineering. 27: 247-52. PMID 18553665 DOI: 10.1002/Bit.260270306  0.379
2009 Atlow SC, Bonadonna-Aparo L, Klibanov AM. Dephenolization of industrial wastewaters catalyzed by polyphenol oxidase. Biotechnology and Bioengineering. 26: 599-603. PMID 18553376 DOI: 10.1002/Bit.260260607  0.434
2009 Pelsy G, Klibanov AM. Preparative separation of alpha- and beta-naphthols catalyzed by immobilized sulfatase. Biotechnology and Bioengineering. 25: 919-28. PMID 18548709 DOI: 10.1002/Bit.260250404  0.395
2009 Klibanov AM, Alberti BN, Zale SE. Enzymatic synthesis of formic acid from H2 and CO2 and production of hydrogen from formic acid. Biotechnology and Bioengineering. 24: 25-36. PMID 18546098 DOI: 10.1002/Bit.260240104  0.395
2008 Antipov E, Cho AE, Wittrup KD, Klibanov AM. Highly L and D enantioselective variants of horseradish peroxidase discovered by an ultrahigh-throughput selection method. Proceedings of the National Academy of Sciences of the United States of America. 105: 17694-9. PMID 19004779 DOI: 10.1073/Pnas.0809851105  0.43
2008 Mukherjee K, Rivera JJ, Klibanov AM. Practical aspects of hydrophobic polycationic bactericidal "paints". Applied Biochemistry and Biotechnology. 151: 61-70. PMID 18327545 DOI: 10.1007/S12010-008-8151-1  0.412
2008 Haldar J, Chen J, Tumpey TM, Gubareva LV, Klibanov AM. Hydrophobic polycationic coatings inactivate wild-type and zanamivir- and/or oseltamivir-resistant human and avian influenza viruses. Biotechnology Letters. 30: 475-9. PMID 17972018 DOI: 10.1007/S10529-007-9565-5  0.621
2007 Lipovsek D, Antipov E, Armstrong KA, Olsen MJ, Klibanov AM, Tidor B, Wittrup KD. Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display. Chemistry & Biology. 14: 1176-85. PMID 17961829 DOI: 10.1016/J.Chembiol.2007.09.008  0.404
2007 Haldar J, Weight AK, Klibanov AM. Preparation, application and testing of permanent antibacterial and antiviral coatings. Nature Protocols. 2: 2412-7. PMID 17947982 DOI: 10.1038/Nprot.2007.353  0.636
2007 Devitt G, Thomas M, Klibanov AM, Pfeiffer T, Bosch V. Optimized protocol for the large scale production of HIV pseudovirions by transient transfection of HEK293T cells with linear fully deacylated polyethylenimine. Journal of Virological Methods. 146: 298-304. PMID 17719656 DOI: 10.1016/J.Jviromet.2007.07.011  0.746
2007 Thomas M, Lu JJ, Chen J, Klibanov AM. Non-viral siRNA delivery to the lung. Advanced Drug Delivery Reviews. 59: 124-33. PMID 17459519 DOI: 10.1016/J.Addr.2007.03.003  0.741
2007 Thomas M, Lu JJ, Zhang C, Chen J, Klibanov AM. Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library. Pharmaceutical Research. 24: 1564-71. PMID 17385014 DOI: 10.1007/S11095-007-9279-3  0.761
2007 Watanabe W, Thomas M, Clarke R, Klibanov AM, Langer R, Katstra J, Fuller GG, Griel LC, Fiegel J, Edwards D. Why inhaling salt water changes what we exhale. Journal of Colloid and Interface Science. 307: 71-8. PMID 17161415 DOI: 10.1016/J.Jcis.2006.11.017  0.389
2007 Rojas AM, Gonzalez PA, Antipov E, Klibanov AM. Specificity of a DNA-based (DNAzyme) peroxidative biocatalyst. Biotechnology Letters. 29: 227-32. PMID 17091371 DOI: 10.1007/S10529-006-9228-Y  0.435
2007 Sharma VK, Klibanov AM. Moisture-induced aggregation of lyophilized DNA and its prevention. Pharmaceutical Research. 24: 168-75. PMID 17041790 DOI: 10.1007/S11095-006-9138-7  0.373
2007 Klibanov AM. Permanently microbicidal materials coatings Journal of Materials Chemistry. 17: 2479-2482. DOI: 10.1039/B702079A  0.364
2006 Cox FC, Sharma VK, Klibanov AM, Wu BI, Kong JA, Engels DW. A method to investigate non-thermal effects of radio frequency radiation on pharmaceuticals with relevance to RFID technology. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 4340-3. PMID 17946239 DOI: 10.1109/IEMBS.2006.259691  0.218
2006 Haldar J, An D, Alvarez de Cienfuegos L, Chen J, Klibanov AM. Polymeric coatings that inactivate both influenza virus and pathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 103: 17667-71. PMID 17101983 DOI: 10.1073/Pnas.0608803103  0.772
2006 Yu JH, Klibanov AM. Co-lyophilization with D-proline greatly enhances peroxidase's stereoselectivity in a non-aqueous medium. Biotechnology Letters. 28: 555-8. PMID 16614892 DOI: 10.1007/S10529-006-0018-3  0.38
2006 Park D, Wang J, Klibanov AM. One-step, painting-like coating procedures to make surfaces highly and permanently bactericidal. Biotechnology Progress. 22: 584-9. PMID 16599580 DOI: 10.1021/Bp0503383  0.414
2005 Chakrabarti R, Klibanov AM, Friesner RA. Sequence optimization and designability of enzyme active sites. Proceedings of the National Academy of Sciences of the United States of America. 102: 12035-40. PMID 16103370 DOI: 10.1073/Pnas.0505397102  0.404
2005 Chakrabarti R, Klibanov AM, Friesner RA. Computational prediction of native protein ligand-binding and enzyme active site sequences. Proceedings of the National Academy of Sciences of the United States of America. 102: 10153-8. PMID 15998733 DOI: 10.1073/Pnas.0504023102  0.403
2005 Thomas M, Ge Q, Lu JJ, Klibanov AM, Chen J. Polycation-mediated delivery of siRNAs for prophylaxis and treatment of influenza virus infection. Expert Opinion On Biological Therapy. 5: 495-505. PMID 15934828 DOI: 10.1517/14712598.5.4.495  0.744
2005 Lewis K, Klibanov AM. Surpassing nature: rational design of sterile-surface materials. Trends in Biotechnology. 23: 343-8. PMID 15922467 DOI: 10.1016/J.Tibtech.2005.05.004  0.352
2005 Thomas M, Ge Q, Lu JJ, Chen J, Klibanov AM. Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo. Pharmaceutical Research. 22: 373-80. PMID 15835742 DOI: 10.1007/S11095-004-1874-Y  0.76
2005 Thomas M, Lu JJ, Ge Q, Zhang C, Chen J, Klibanov AM. Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. Proceedings of the National Academy of Sciences of the United States of America. 102: 5679-84. PMID 15824322 DOI: 10.1073/Pnas.0502067102  0.761
2005 Sharma VK, Thomas M, Klibanov AM. Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention. Biotechnology and Bioengineering. 90: 614-20. PMID 15818564 DOI: 10.1002/Bit.20444  0.754
2005 Varga CM, Tedford NC, Thomas M, Klibanov AM, Griffith LG, Lauffenburger DA. Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes. Gene Therapy. 12: 1023-32. PMID 15815703 DOI: 10.1038/Sj.Gt.3302495  0.376
2005 Milović NM, Wang J, Lewis K, Klibanov AM. Immobilized N-alkylated polyethylenimine avidly kills bacteria by rupturing cell membranes with no resistance developed. Biotechnology and Bioengineering. 90: 715-22. PMID 15803464 DOI: 10.1002/Bit.20454  0.396
2005 Akinc A, Thomas M, Klibanov AM, Langer R. Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. The Journal of Gene Medicine. 7: 657-63. PMID 15543529 DOI: 10.1002/Jgm.696  0.765
2004 Gelman F, Lewis K, Klibanov AM. Drastically lowering the titer of waterborne bacteriophage PRD1 by exposure to immobilized hydrophobic polycations. Biotechnology Letters. 26: 1695-700. PMID 15604821 DOI: 10.1007/S10529-004-3737-3  0.406
2004 Klibanov AM, Schefiliti JA. On the relationship between conformation and stability in solid pharmaceutical protein formulations. Biotechnology Letters. 26: 1103-6. PMID 15372733 DOI: 10.1023/B:Bile.0000035520.47933.A6  0.397
2004 Dzyuba SV, Klibanov AM. Stereoselective oxidations and reductions catalyzed by nonredox proteins Tetrahedron Asymmetry. 15: 2771-2777. DOI: 10.1016/J.Tetasy.2004.04.035  0.373
2003 Dzyuba SV, Klibanov AM. Asymmetric thiosulfinations catalyzed by bovine serum albumin and horseradish peroxidase. Biotechnology Letters. 25: 1961-5. PMID 14719806 DOI: 10.1023/B:Bile.0000004385.50406.06  0.411
2003 Lin J, Murthy SK, Olsen BD, Gleason KK, Klibanov AM. Making thin polymeric materials, including fabrics, microbicidal and also water-repellent. Biotechnology Letters. 25: 1661-5. PMID 14584925 DOI: 10.1023/A:1025613814588  0.397
2003 Chakrabarti R, Klibanov AM. Nanocrystals modified with peptide nucleic acids (PNAs) for selective self-assembly and DNA detection. Journal of the American Chemical Society. 125: 12531-40. PMID 14531698 DOI: 10.1021/Ja035399G  0.358
2003 Klibanov AM. Asymmetric enzymatic oxidoreductions in organic solvents. Current Opinion in Biotechnology. 14: 427-31. PMID 12943853 DOI: 10.1016/S0958-1669(03)00074-0  0.469
2003 Thomas M, Klibanov AM. Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 9138-43. PMID 12886020 DOI: 10.1073/Pnas.1233634100  0.755
2003 Fu K, Harrell R, Zinski K, Um C, Jaklenec A, Frazier J, Lotan N, Burke P, Klibanov AM, Langer R. A potential approach for decreasing the burst effect of protein from PLGA microspheres. Journal of Pharmaceutical Sciences. 92: 1582-91. PMID 12884245 DOI: 10.1002/Jps.10414  0.403
2003 Lin J, Qiu S, Lewis K, Klibanov AM. Mechanism of bactericidal and fungicidal activities of textiles covalently modified with alkylated polyethylenimine. Biotechnology and Bioengineering. 83: 168-72. PMID 12768622 DOI: 10.1002/Bit.10651  0.396
2003 Thomas M, Klibanov AM. Non-viral gene therapy: polycation-mediated DNA delivery. Applied Microbiology and Biotechnology. 62: 27-34. PMID 12719940 DOI: 10.1007/S00253-003-1321-8  0.369
2003 Kamiya N, Klibanov AM. Controling the rate of protein release from polyelectrolyte complexes. Biotechnology and Bioengineering. 82: 590-4. PMID 12652482 DOI: 10.1002/Bit.10606  0.35
2002 Xie Y, Das PK, Caaveiro JM, Klibanov AM. Unexpectedly enhanced stereoselectivity of peroxidase-catalyzed sulfoxidation in branched alcohols. Biotechnology and Bioengineering. 79: 105-11. PMID 17590936 DOI: 10.1002/Bit.10308  0.442
2002 Thomas M, Klibanov AM. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 14640-5. PMID 12403826 DOI: 10.1073/Pnas.192581499  0.765
2002 Lin J, Qiu S, Lewis K, Klibanov AM. Bactericidal properties of flat surfaces and nanoparticles derivatized with alkylated polyethylenimines. Biotechnology Progress. 18: 1082-6. PMID 12363361 DOI: 10.1021/Bp025597W  0.394
2002 Fisher NG, Christiansen JP, Klibanov A, Taylor RP, Kaul S, Lindner JR. Influence of microbubble surface charge on capillary transit and myocardial contrast enhancement Journal of the American College of Cardiology. 40: 811-819. PMID 12204515 DOI: 10.1016/S0735-1097(02)02038-7  0.241
2002 Villanueva FS, Klibanov A, Wagner WR. Microbubble-endothelial cell interactions as a basis for assessing endothelial function. Echocardiography (Mount Kisco, N.Y.). 19: 427-38. PMID 12174207 DOI: 10.1046/J.1540-8175.2002.00427.X  0.193
2002 Tiller JC, Lee SB, Lewis K, Klibanov AM. Polymer surfaces derivatized with poly(vinyl-N-hexylpyridinium) kill airborne and waterborne bacteria. Biotechnology and Bioengineering. 79: 465-71. PMID 12115410 DOI: 10.1002/Bit.10299  0.385
2002 Das PK, Caaveiro JM, Luque S, Klibanov AM. Asymmetric sulfoxidations mediated by alpha-chymotrypsin. Biotechnology and Bioengineering. 78: 104-9. PMID 11857286 DOI: 10.1002/Bit.10187  0.439
2002 Das PK, Caaveiro JM, Luque S, Klibanov AM. Binding of hydrophobic hydroxamic acids enhances peroxidase's stereoselectivity in nonaqueous sulfoxidations. Journal of the American Chemical Society. 124: 782-7. PMID 11817954 DOI: 10.1021/Ja012075O  0.384
2002 Lin J, Tiller JC, Lee SB, Lewis K, Klibanov AM. Insights into bactericidal action of surface-attached poly(vinyl-N-hexylpyridinium) chains Biotechnology Letters. 24: 801-805. DOI: 10.1023/A:1015584423358  0.359
2001 Choi WS, Murthy GG, Edwards DA, Langer R, Klibanov AM. Inhalation delivery of proteins from ethanol suspensions. Proceedings of the National Academy of Sciences of the United States of America. 98: 11103-7. PMID 11562495 DOI: 10.1073/Pnas.201413798  0.379
2001 Tiller JC, Liao CJ, Lewis K, Klibanov AM. Designing surfaces that kill bacteria on contact. Proceedings of the National Academy of Sciences of the United States of America. 98: 5981-5. PMID 11353851 DOI: 10.1073/Pnas.111143098  0.386
2001 Tiller JC, Bonner G, Pan LC, Klibanov AM. Improving biomaterial properties of collagen films by chemical modification. Biotechnology and Bioengineering. 73: 246-52. PMID 11257607 DOI: 10.1002/Bit.1057  0.371
2001 Klibanov AM. Improving enzymes by using them in organic solvents. Nature. 409: 241-6. PMID 11196652 DOI: 10.1038/35051719  0.458
2001 Yuchun X, Das PK, Klibanov AM. Excipients activate peroxidases in specific but not in non-specific reactions in organic solvents Biotechnology Letters. 23: 1451-1454. DOI: 10.1023/A:1011641622960  0.44
2001 Mathiowitz E, Jacob JS, Jong YS, Hekal TM, Spano W, Guemonprez R, Klibanov AM, Langer R. Novel desiccants based on designed polymeric blends Journal of Applied Polymer Science. 80: 317-327. DOI: 10.1002/1097-4628(20010418)80:3<317::Aid-App1102>3.0.Co;2-Q  0.364
2000 Dai L, Klibanov AM. Simple technique for simultaneous on-line estimation of biomass and acetate from base consumption and conductivity measurements in high-cell density cultures of Escherichia coli Biotechnology and Bioengineering. 70: 358-361. PMID 10992241 DOI: 10.1002/1097-0290(20001105)70:3<358::AID-BIT14>3.0.CO;2-T  0.227
2000 Dai L, Klibanov AM. Peroxidase-catalyzed asymmetric sulfoxidation in organic solvents versus in water. Biotechnology and Bioengineering. 70: 353-7. PMID 10992240 DOI: 10.1002/1097-0290(20001105)70:3<353::Aid-Bit13>3.0.Co;2-0  0.423
2000 Shin JS, Luque S, Klibanov AM. Improving lipase enantioselectivity in organic solvents by forming substrate salts with chiral agents. Biotechnology and Bioengineering. 69: 577-83. PMID 10898867 DOI: 10.1002/1097-0290(20000905)69:5<577::Aid-Bit12>3.0.Co;2-Y  0.405
2000 Burova TV, Grinberg NV, Grinberg VY, Rariy RV, Klibanov AM. Calorimetric evidence for a native-like conformation of hen egg-white lysozyme dissolved in glycerol. Biochimica Et Biophysica Acta. 1478: 309-17. PMID 10825542 DOI: 10.1016/S0167-4838(00)00028-5  0.396
2000 Bonner G, Klibanov AM. Structural stability of DNA in nonaqueous solvents. Biotechnology and Bioengineering. 68: 339-44. PMID 10745202 DOI: 10.1002/(Sici)1097-0290(20000505)68:3<339::Aid-Bit12>3.0.Co;2-O  0.397
2000 Fu K, Pack DW, Klibanov AM, Langer R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres. Pharmaceutical Research. 17: 100-6. PMID 10714616 DOI: 10.1023/A:1007582911958  0.37
2000 Klibanov AM, Samokhin GP, Martinek K, Berezin IV. A new approach to preparative enzymatic synthesis. Reprinted from Biotechnology and Bioengineering, Vol. XIX, No. 9, Pages 1351-1361. Biotechnology and Bioengineering. 67: 737-47. PMID 10699855 DOI: 10.1002/(SICI)1097-0290(20000320)67:6<737::AID-BIT12>3.0.CO;2-2  0.702
2000 Klibanov AM. Answering the question: 'why did biocatalysis in organic media not take off in the 1930s?'. Trends in Biotechnology. 18: 85-6. PMID 10675893 DOI: 10.1016/S0167-7799(99)01404-3  0.338
2000 Fu K, Klibanov AM, Langer R. Protein stability in controlled-release systems. Nature Biotechnology. 18: 24-5. PMID 10625383 DOI: 10.1038/71875  0.343
2000 Rariy RV, Klibanov AM. On the relationship between enzymatic enantioselectivity in organic solvents and enzyme flexibility Biocatalysis and Biotransformation. 18: 401-407. DOI: 10.3109/10242420009015259  0.453
2000 Ozawa S, Klibanov AM. Myoglobin-catalyzed epoxidation of styrene in organic solvents accelerated by bioimprinting Biotechnology Letters. 22: 1269-1272. DOI: 10.1023/A:1005640915361  0.406
2000 Arredondo AR, Dorval BL, Klibanov AM, Lewis K. Rapid immunodetection of Escherichia coli Biotechnology Letters. 22: 547-550. DOI: 10.1023/A:1005616523897  0.358
2000 Klibanov AM, Samokhin GP, Imartinek K, Berezin IV. A new approach to preparative enzymatic synthesis Biotechnology and Bioengineering. 67: 744-747.  0.656
1999 Dai L, Klibanov AM. Striking activation of oxidative enzymes suspended in nonaqueous media. Proceedings of the National Academy of Sciences of the United States of America. 96: 9475-8. PMID 10449717 DOI: 10.1073/Pnas.96.17.9475  0.48
1999 Knubovets T, Osterhout JJ, Klibanov AM. Structure of lysozyme dissolved in neat organic solvents as assessed by NMR and CD spectroscopies. Biotechnology and Bioengineering. 63: 242-8. PMID 10099601 DOI: 10.1002/(Sici)1097-0290(19990420)63:2<242::Aid-Bit13>3.0.Co;2-N  0.391
1999 Fu K, Griebenow K, Hsieh L, Klibanov AM, LangerR. FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres. Journal of Controlled Release : Official Journal of the Controlled Release Society. 58: 357-66. PMID 10099160 DOI: 10.1016/S0168-3659(98)00192-8  0.625
1999 Knubovets T, Osterhout JJ, Connolly PJ, Klibanov AM. Structure, thermostability, and conformational flexibility of hen egg-white lysozyme dissolved in glycerol. Proceedings of the National Academy of Sciences of the United States of America. 96: 1262-7. PMID 9990012 DOI: 10.1073/Pnas.96.4.1262  0.38
1999 Rariy RV, Klibanov AM. Protein refolding in predominantly organic media markedly enhanced by common salts Biotechnology and Bioengineering. 62: 704-710. PMID 9951526 DOI: 10.1002/(Sici)1097-0290(19990320)62:6<704::Aid-Bit9>3.0.Co;2-S  0.42
1999 Ke T, Rariy RV, Schmitke JL, Klibanov AM. Computational and experimental examination of the effect of inorganic salts on chymotryptic enantioselectivity in water Biocatalysis and Biotransformation. 17: 81-93. DOI: 10.3109/10242429909015224  0.451
1999 Ke T, Klibanov AM. Markedly enhancing enzymatic enantioselectivity in organic solvents by forming substrate salts Journal of the American Chemical Society. 121: 3334-3340. DOI: 10.1021/Ja984283V  0.427
1998 Ke T, Klibanov AM. On enzymatic activity in organic solvents as a function of enzyme history. Biotechnology and Bioengineering. 57: 746-50. PMID 10099254 DOI: 10.1002/(Sici)1097-0290(19980320)57:6<746::Aid-Bit12>3.0.Co;2-5  0.482
1998 Ke T, Tidor B, Klibanov AM. Molecular-modeling calculations of enzymatic enantioselectivity taking hydration into account. Biotechnology and Bioengineering. 57: 741-5. PMID 10099253 DOI: 10.1002/(Sici)1097-0290(19980320)57:6<741::Aid-Bit11>3.0.Co;2-A  0.408
1998 Schmitke JL, Stern LJ, Klibanov AM. Comparison of x-ray crystal structures of an acyl-enzyme intermediate of subtilisin Carlsberg formed in anhydrous acetonitrile and in water. Proceedings of the National Academy of Sciences of the United States of America. 95: 12918-23. PMID 9789015 DOI: 10.1073/Pnas.95.22.12918  0.453
1998 Schmitke JL, Stern LJ, Klibanov AM. Organic solvent binding to crystalline subtilisin1 in mostly aqueous media and in the neat solvents. Biochemical and Biophysical Research Communications. 248: 273-7. PMID 9675126 DOI: 10.1006/Bbrc.1998.8937  0.444
1998 Costantino HR, Schwendeman SP, Langer R, Klibanov AM. Deterioration of lyophilized pharmaceutical proteins Biochemistry (Moscow). 63: 357-363. PMID 9526132  0.3
1998 Luque S, Ke T, Klibanov AM. On the role of transition-state substrate desolvation in enzymatic enantioselectivity in aqueous-organic mixtures Biocatalysis and Biotransformation. 16: 233-248. DOI: 10.3109/10242429809003201  0.457
1998 Ke T, Klibanov AM. Insights into the solvent dependence of chymotryptic prochiral selectivity Journal of the American Chemical Society. 120: 4259-4263. DOI: 10.1021/Ja9802201  0.37
1997 Xu K, Griebenow K, Klibanov AM. Correlation between catalytic activity and secondary structure of subtilisin dissolved in organic solvents. Biotechnology and Bioengineering. 56: 485-91. PMID 18642269 DOI: 10.1002/(Sici)1097-0290(19971205)56:5<485::Aid-Bit2>3.0.Co;2-E  0.65
1997 Wescott CR, Klibanov AM. Thermodynamic analysis of solvent effect on substrate specificity of lyophilized enzymes suspended in organic media. Biotechnology and Bioengineering. 56: 340-4. PMID 18636650 DOI: 10.1002/(Sici)1097-0290(19971105)56:3<340::Aid-Bit12>3.0.Co;2-K  0.458
1997 Griebenow K, Klibanov AM. Can conformational changes be responsible for solvent and excipient effects on the catalytic behavior of subtilisin Carlsberg in organic solvents? Biotechnology and Bioengineering. 53: 351-62. PMID 18634023 DOI: 10.1002/(Sici)1097-0290(19970220)53:4<351::Aid-Bit1>3.0.Co;2-M  0.655
1997 Costantino HR, Griebenow K, Langer R, Klibanov AM. On the pH memory of lyophilized compounds containing protein functional groups. Biotechnology and Bioengineering. 53: 345-8. PMID 18633990 DOI: 10.1002/(Sici)1097-0290(19970205)53:3<345::Aid-Bit14>3.0.Co;2-J  0.602
1997 Rariy RV, Klibanov AM. Correct protein folding in glycerol Proceedings of the National Academy of Sciences of the United States of America. 94: 13520-13523. PMID 9391058 DOI: 10.1073/Pnas.94.25.13520  0.455
1997 Schmitke JL, Stern LJ, Klibanov AM. The crystal structure of subtilisin Carlsberg in anhydrous dioxane and its comparison with those in water and acetonitrile. Proceedings of the National Academy of Sciences of the United States of America. 94: 4250-5. PMID 9113975 DOI: 10.1073/Pnas.94.9.4250  0.394
1997 Klibanov AM. Why are enzymes less active in organic solvents than in water? Trends in Biotechnology. 15: 97-101. PMID 9080715 DOI: 10.1016/S0167-7799(97)01013-5  0.438
1997 Costantino HR, Shieh L, Klibanov AM, Langer R. Heterogeneity of serum albumin samples with respect to solid-state aggregation via thiol-disulfide interchange - Implications for sustained release from polymers Journal of Controlled Release. 44: 255-261. DOI: 10.1016/S0168-3659(96)01528-3  0.398
1997 Costantino HR, Liauw S, Mitragotri S, Langer R, Klibanov AM, Sluzky V. The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions Acs Symposium Series. 675: 29-66.  0.192
1996 Mishra P, Griebenow K, Klibanov AM. Structural basis for the molecular memory of imprinted proteins in anhydrous media. Biotechnology and Bioengineering. 52: 609-14. PMID 18629934 DOI: 10.1002/(Sici)1097-0290(19961205)52:5<609::Aid-Bit8>3.0.Co;2-N  0.616
1996 Costantino HR, Schwendeman SP, Griebenow K, Klibanov AM, Langer R. The secondary structure and aggregation of lyophilized tetanus toxoid. Journal of Pharmaceutical Sciences. 85: 1290-3. PMID 8961141 DOI: 10.1021/Js960148+  0.613
1996 Griebenow K, Klibanov AM. On protein denaturation in aqueous-organic mixtures but not in pure organic solvents Journal of the American Chemical Society. 118: 11695-11700. DOI: 10.1021/Ja961869D  0.639
1996 Xu K, Klibanov AM. pH control of the catalytic activity of cross-linked enzyme crystals in organic solvents Journal of the American Chemical Society. 118: 9815-9819. DOI: 10.1021/Ja961596M  0.461
1996 Wescott CR, Noritomi H, Klibanov AM. Rational control of enzymatic enantioselectivity through solvation thermodynamics Journal of the American Chemical Society. 118: 10365-10370. DOI: 10.1021/Ja961394Q  0.415
1996 Schmitke JL, Wescott CR, Klibanov AM. The mechanistic dissection of the plunge in enzymatic activity upon transition from water to anhydrous solvents Journal of the American Chemical Society. 118: 3360-3365. DOI: 10.1021/Ja9539958  0.439
1996 Ke T, Wescott CR, Klibanov AM. Prediction of the solvent dependence of enzymatic prochiral selectivity by means of structure-based thermodynamic calculations Journal of the American Chemical Society. 118: 3366-3374. DOI: 10.1021/Ja952674T  0.37
1996 Noritomi H, Almarsson O, Barletta GL, Klibanov AM. The influence of the mode of enzyme preparation on enzymatic enantioselectivity in organic solvents and its temperature dependence Biotechnology and Bioengineering. 51: 95-99. DOI: 10.1002/(Sici)1097-0290(19960705)51:1<95::Aid-Bit11>3.0.Co;2-3  0.44
1996 Louwrier A, Drtina GJ, Klibanov AM. On the issue of interfacial activation of lipase in nonaqueous media Biotechnology and Bioengineering. 50: 1-5. DOI: 10.1002/(Sici)1097-0290(19960405)50:1<1::Aid-Bit1>3.0.Co;2-L  0.433
1996 Almarsson Ö, Klibanov AM. Remarkable activation of enzymes in nonaqueous media by denaturing organic cosolvents Biotechnology and Bioengineering. 49: 87-92. DOI: 10.1002/(Sici)1097-0290(19960105)49:1<87::Aid-Bit11>3.0.Co;2-8  0.487
1995 Magner E, Klibanov AM. The oxidation of chiral alcohols catalyzed by catalase in organic solvents. Biotechnology and Bioengineering. 46: 175-9. PMID 18623277 DOI: 10.1002/Bit.260460211  0.425
1995 Costantino HR, Langer R, Klibanov AM. Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: Effect of moisture and stabilization by excipients Nature Biotechnology. 13: 493-496. PMID 9634790 DOI: 10.1038/Nbt0595-493  0.399
1995 Bromberg LE, Klibanov AM. Transport of proteins dissolved in organic solvents across biomimetic membranes Proceedings of the National Academy of Sciences of the United States of America. 92: 1262-1266. PMID 7877966 DOI: 10.1073/Pnas.92.5.1262  0.399
1995 Klibanov AM. Enzyme memory. What is remembered and why? Nature. 374: 596. PMID 7715696 DOI: 10.1038/374596A0  0.362
1995 Ferrante AA, Augliera J, Lewis K, Klibanov AM. Cloning of an organic solvent-resistance gene in Escherichia coli: The unexpected role of alkylhydroperoxide reductase Proceedings of the National Academy of Sciences of the United States of America. 92: 7617-7621. PMID 7644465 DOI: 10.1073/Pnas.92.17.7617  0.398
1995 Costantino HR, Griebenow K, Mishra P, Langer R, Klibanov AM. Fourier-transform infrared spectroscopic investigation of protein stability in the lyophilized form. Biochimica Et Biophysica Acta. 1253: 69-74. PMID 7492602 DOI: 10.1016/0167-4838(95)00156-O  0.627
1995 Schwendeman SP, Costantino HR, Gupta RK, Siber GR, Klibanov AM, Langer R. Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation Proceedings of the National Academy of Sciences of the United States of America. 92: 11234-11238. PMID 7479971 DOI: 10.1073/Pnas.92.24.11234  0.35
1995 Griebenow K, Klibanov AM. Lyophilization-induced reversible changes in the secondary structure of proteins. Proceedings of the National Academy of Sciences of the United States of America. 92: 10969-76. PMID 7479920 DOI: 10.1073/Pnas.92.24.10969  0.602
1995 Desai UR, Klibanov AM. Assessing the structural integrity of a lyophilized protein in organic solvents Journal of the American Chemical Society. 117: 3940-3945. DOI: 10.1021/Ja00119A007  0.693
1995 Magner E, Klibanov AM. The oxidation of chiral alcohols catalyzed by catalase in organic solvents Biotechnology and Bioengineering. 46: 175-179. DOI: 10.1002/bit.260460211  0.572
1995 Klibanov AM. Send-off for a new journal Journal of Molecular Catalysis. B, Enzymatic. 1: v.  0.179
1995 Klibanov AM. What is remembered and why? Nature. 374: 596.  0.173
1994 Orsat B, Drtina GJ, Williams MG, Klibanov AM. Effect of support material and enzyme pretreatment on enantioselectivity of immobilized subtilisin in organic solvents. Biotechnology and Bioengineering. 44: 1265-9. PMID 18618554 DOI: 10.1002/Bit.260441015  0.458
1994 Chin JT, Wheeler SL, Klibanov AM. On protein solubility in organic solvent. Biotechnology and Bioengineering. 44: 140-5. PMID 18618457 DOI: 10.1002/Bit.260440120  0.448
1994 Fitzpatrick PA, Ringe D, Klibanov AM. X-ray crystal structure of cross-linked subtilisin Carlsberg in water vs. acetonitrile Biochemical and Biophysical Research Communications. 198: 675-681. PMID 8297378 DOI: 10.1006/Bbrc.1994.1098  0.378
1994 Bromberg LE, Klibanov AM. Detergent-enabled transport of proteins and nucleic acids through hydrophobic solvents Proceedings of the National Academy of Sciences of the United States of America. 91: 143-147. PMID 8278355 DOI: 10.1073/Pnas.91.1.143  0.393
1994 Wescott CR, Klibanov AM. The solvent dependence of enzyme specificity Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1206: 1-9. PMID 8186238 DOI: 10.1016/0167-4838(94)90065-5  0.457
1994 Costantino HR, Langer R, Klibanov AM. Moisture-Induced Aggregation of Lyophilized Insulin Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 11: 21-29. PMID 8140052 DOI: 10.1023/A:1018981208076  0.368
1994 Costantino HR, Langer R, Klibanov AM. Solid-phase aggregation of proteins under pharmaceutically relevant conditions Journal of Pharmaceutical Sciences. 83: 1662-1669. PMID 7891292 DOI: 10.1002/Jps.2600831205  0.404
1994 Desai UR, Osterhout JJ, Klibanov AM. Protein structure in the lyophilized state: A hydrogen isotope exchange/NMR study with bovine pancreatic trypsin inhibitor Journal of the American Chemical Society. 116: 9420-9422. DOI: 10.1021/Ja00100A002  0.686
1994 Orsat B, Drtina GJ, Williams MG, Klibanov AM. Effect of support material and enzyme pretreatment on enantioselectivity of immobilized subtilisin in organic solvents Biotechnology and Bioengineering. 44: 1265-1269. DOI: 10.1002/bit.260441015  0.343
1994 Chin JT, Wheeler SL, Klibanov AM. Commullication to the editor on protein solubility in organic solvents Biotechnology and Bioengineering. 44: 140-145. DOI: 10.1002/bit.260440120  0.298
1993 Narayan VS, Klibanov AM. Are water-immiscibility and apolarity of the solvent relevant to enzyme efficiency? Biotechnology and Bioengineering. 41: 390-3. PMID 18609564 DOI: 10.1002/Bit.260410314  0.443
1993 Fitzpatrick PA, Steinmetz ACU, Ringe D, Klibanov AM. Enzyme crystal structure in a neat organic solvent Proceedings of the National Academy of Sciences of the United States of America. 90: 8653-8657. PMID 8378343 DOI: 10.1073/Pnas.90.18.8653  0.431
1993 Tawaki S, Klibanov AM. Chemoselectivity of enzymes in anhydrous media is strongly solvent dependent Biocatalysis and Biotransformation. 8: 3-19. DOI: 10.3109/10242429309030952  0.357
1993 Wescott CR, Klibanov AM. Predicting the solvent dependence of enzymatic substrate specificity using semiempirical thermodynamic calculations Journal of the American Chemical Society. 115: 10360-10361. DOI: 10.1021/Ja00075A063  0.449
1993 Wescott CR, Klibanov AM. Solvent variation inverts substrate specificity of an enzyme Journal of the American Chemical Society. 115: 1629-1631. DOI: 10.1021/Ja00058A002  0.442
1993 Terradas F, Teston-Henry M, Fitzpatrick PA, Klibanov AM. Marked dependence of enzyme prochiral selectivity on the solvent Journal of the American Chemical Society. 115: 390-396. DOI: 10.1021/Ja00055A004  0.459
1993 Ikeda I, Klibanov AM. Lipase-catalyzed acylation of sugars solubilized in hydrophobic solvents by complexation Biotechnology and Bioengineering. 42: 788-791. DOI: 10.1002/Bit.260420616  0.404
1993 Burke PA, Griffin RG, Klibanov AM. Solid-state nuclear magnetic resonance investigation of solvent dependence of tyrosyl ring motion in an enzyme Biotechnology and Bioengineering. 42: 87-94. DOI: 10.1002/Bit.260420112  0.44
1993 Dabulis K, Klibanov AM. Dramatic enhancement of enzymatic activity in organic solvents by lyoprotectants Biotechnology and Bioengineering. 41: 566-571. DOI: 10.1002/Bit.260410509  0.478
1992 Sluzky V, Klibanov AM, Langer R. Mechanism of insulin aggregation and stabilization in agitated aqueous solutions Biotechnology and Bioengineering. 40: 895-903. PMID 18601196 DOI: 10.1002/Bit.260400805  0.374
1992 Volkin DB, Klibanov AM. Alterations in the structure of proteins that cause their irreversible inactivation Developments in Biological Standardization. 74: 73-80; discussion 80. PMID 1592187  0.585
1992 Burke PA, Griffin RG, Klibanov AM. Solid-state NMR assessment of enzyme active center structure under nonaqueous conditions Journal of Biological Chemistry. 267: 20057-20064. PMID 1400323  0.385
1992 Tawaki S, Klibanov AM. Inversion of enzyme enantioselectivity mediated by the solvent Journal of the American Chemical Society. 114: 1882-1884. DOI: 10.1021/Ja00031A054  0.456
1992 Klyachko NL, Klibanov AM. Oxidation of Dibenzothiophene Catalyzed by Hemoglobin and Other Hemoproteins in Various Aqueous-Organic Media Applied Biochemistry and Biotechnology. 37: 53-68. DOI: 10.1007/Bf02788857  0.392
1992 Fitzpatrick PA, Ringe D, Klibanov AM. Computer-assisted modeling of subtilisin enantioselectivity in organic solvents Biotechnology and Bioengineering. 40: 735-742. DOI: 10.1002/Bit.260400613  0.424
1992 Chang N, Klibanov AM. Protein chromatography in neat organic solvents Biotechnology and Bioengineering. 39: 575-578. DOI: 10.1002/Bit.260390513  0.412
1992 Dabulis K, Klibanov AM. Molecular imprinting of proteins and other macromolecules resulting in new adsorbents Biotechnology and Bioengineering. 39: 176-185. DOI: 10.1002/Bit.260390209  0.391
1992 Sluzky V, Klibanov AM, Langer R. Mechanism of insulin aggregation and stabilization in agitated aqueous solutions Biotechnology and Bioengineering. 40: 895-903.  0.245
1991 Schulze B, Klibanov AM. Inactivation and stabilization of stabilisins in neat organic solvents. Biotechnology and Bioengineering. 38: 1001-1006. PMID 18600863 DOI: 10.1002/Bit.260380907  0.479
1991 Volkin DB, Staubli A, Langer R, Klibanov AM. Enzyme thermoinactivation in anhydrous organic solvents. Biotechnology and Bioengineering. 37: 843-53. PMID 18600684 DOI: 10.1002/Bit.260370908  0.653
1991 Liu WR, Langer R, Klibanov AM. Moisture-induced aggregation of lyophilized proteins in the solid state. Biotechnology and Bioengineering. 37: 177-184. PMID 18597353 DOI: 10.1002/Bit.260370210  0.41
1991 Chang N, Hen SJ, Klibanov AM. Protein separation and purification in neat dimethyl sulfoxide Biochemical and Biophysical Research Communications. 176: 1462-1468. PMID 2039525 DOI: 10.1016/0006-291X(91)90451-C  0.411
1991 Sluzky V, Tamada JA, Klibanov AM, Langer R. Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces Proceedings of the National Academy of Sciences of the United States of America. 88: 9377-9381. PMID 1946348 DOI: 10.1073/Pnas.88.21.9377  0.366
1991 Kitaguchi H, Ono M, Itoh I, Klibanov AM. Regioselective modification of lysine’s amino groups by proteases Agricultural and Biological Chemistry. 55: 3067-3073. PMID 1368767 DOI: 10.1080/00021369.1991.10857914  0.369
1991 Gardossi L, Bianchi D, Klibanov AM. Selective acylation of peptides catalyzed by lipases in organic solvents Journal of the American Chemical Society. 113: 6328-6329. DOI: 10.1021/Ja00016A091  0.368
1991 Margolin AL, Fitzpatrick PA, Dubin PL, Klibanov AM. Chemoenzymatic Synthesis of Optically Active (Meth)acrylic Polymers Journal of the American Chemical Society. 113: 4693-4694. DOI: 10.1021/Ja00012A055  0.344
1991 Fitzpatrick PA, Klibanov AM. How can the solvent affect enzyme enantioselectivity? Journal of the American Chemical Society. 113: 3166-3171. DOI: 10.1021/Ja00008A054  0.454
1991 Rubio E, Fernandez-Mayorales A, Klibanov AM. Effect of the solvent on enzyme regioselectivity Journal of the American Chemical Society. 113: 695-696. DOI: 10.1021/Ja00002A060  0.454
1991 Burke PA, Klibanov AM. Enzymatic catalysis in organic solvents Reactive Polymers. 15: 228. DOI: 10.1016/0923-1137(91)90182-N  0.397
1991 Schulze B, Klibanov AM. Inactivation and stabilization of subtilisins in neat organic solvents Biotechnology and Bioengineering. 38: 1001-1006.  0.294
1991 Volkin DB, Staubli A, Langer R, Klibanov AM. Enzyme thermoinactivation in anhydrous organic solvents Biotechnology and Bioengineering. 37: 843-853.  0.586
1991 Liu WR, Langer R, Klibanov AM. Moisture-induced aggregation of lyophilized proteins in the solid state Biotechnology and Bioengineering. 37: 177-184.  0.233
1990 Braco L, Dabulis K, Klibanov AM. Production of abiotic receptors by molecular imprinting of proteins Proceedings of the National Academy of Sciences of the United States of America. 87: 274-277. PMID 2153288 DOI: 10.1073/pnas.87.1.274  0.305
1990 Holmberg E, Maruyama K, Kennel S, Klibanov A, Torchilin V, Ryan U, Huang L. Target-Specific Binding of Immunoliposomes in Vivo Journal of Liposome Research. 1: 393-406. DOI: 10.3109/08982109009036003  0.219
1990 KITAGUCHI H, FITZPATRICK PA, HUBER JE, KLIBANOV AM. Enzymatic Resolution of Racemic Amines. Annals of the New York Academy of Sciences. 613: 656-658. DOI: 10.1111/J.1749-6632.1990.Tb18240.X  0.355
1990 Kitaguchi H, Fitzpatrick PA, Huber JE, Klibanov AM. Enzymatic resolution of racemic amines: Crucial role of the solvent Annals of the New York Academy of Sciences. 613: 656-658. DOI: 10.1021/Ja00190A070  0.385
1990 Adams KAH, Chung SH, Klibanov AM. Kinetic isotope effect investigation of enzyme mechanism in organic solvents Journal of the American Chemical Society. 112: 9418-9419. DOI: 10.1021/Ja00181A068  0.441
1990 Klibanov AM. Asymmetric transformations catalyzed by enzymes in organic solvents Accounts of Chemical Research. 23: 114-120. DOI: 10.1021/Ar00172A004  0.433
1990 Dorval BL, Chow M, Klibanov AM. Communications to the editor: Lysine and other diamines dramatically stabilize poliovirus against thermoniactivation Biotechnology and Bioengineering. 35: 1051-1054. DOI: 10.1002/Bit.260351013  0.353
1989 Volkin DB, Klibanov AM. Mechanism of thermoinactivation of immobilized glucose isomerase. Biotechnology and Bioengineering. 33: 1104-11. PMID 18588027 DOI: 10.1002/Bit.260330905  0.599
1989 Russell AJ, Trudel LJ, Skipper PL, Groopman JD, Tannenbaum SR, Klibanov AM. Antibody-antigen binding in organic solvents Biochemical and Biophysical Research Communications. 158: 80-85. PMID 2912456 DOI: 10.1016/S0006-291X(89)80179-2  0.374
1989 Barzana E, Klibanov AM, Karel M. A colorimetric method for the enzymatic analysis of gases: The determination of ethanol and formaldehyde vapors using solid alcohol oxidase Analytical Biochemistry. 182: 109-115. PMID 2690675 DOI: 10.1016/0003-2697(89)90726-4  0.356
1989 Klibanov AM. Enzymatic catalysis in anhydrous organic solvents Trends in Biochemical Sciences. 14: 141-144. PMID 2658221 DOI: 10.1016/0968-0004(89)90146-1  0.438
1989 Russell AJ, Klibanov AM. Enzymes in organic solvents Biochemical Society Transactions. 17: 1145. PMID 2628121 DOI: 10.1042/Bst0171145  0.445
1989 Dorval BL, Chow M, Klibanov AM. Stabilization of poliovirus against heat inactivation Biochemical and Biophysical Research Communications. 159: 1177-1183. PMID 2539143 DOI: 10.1016/0006-291X(89)92234-1  0.361
1989 Kitaguchi H, Klibanov AM. Enzymatic peptide synthesis via segment condensation in the presence of water mimics Journal of the American Chemical Society. 111: 9272-9273. DOI: 10.1021/Ja00208A044  0.345
1989 Burke PA, Smith SO, Bachovchin WW, Klibanov AM. Demonstration of structural integrity of an enzyme in organic solvents by solid-state NMR Journal of the American Chemical Society. 111: 8290-8291. DOI: 10.1021/Ja00203A046  0.422
1989 Kanerva LT, Klibanov AM. Hammett analysis of enzyme action in organic solvents Journal of the American Chemical Society. 111: 6864-6865. DOI: 10.1021/Ja00199A069  0.438
1989 Chinsky N, Margolin AL, Klibanov AM. Chemoselective enzymatic monoacylation of bifunctional compounds Journal of the American Chemical Society. 111: 386-388. DOI: 10.1021/Ja00183A069  0.314
1988 Million CJ, Klibanov AM, Langer R. Kinetics of bilirubin oxidase and modeling of an immobilized bilirubin oxidase reactor for bilirubin detoxification. Biotechnology and Bioengineering. 31: 536-46. PMID 18584643 DOI: 10.1002/Bit.260310605  0.348
1988 Ahern TJ, Klibanov AM. Analysis of processes causing thermal inactivation of enzymes. Methods of Biochemical Analysis. 33: 91-127. PMID 3282153 DOI: 10.1002/9780470110546.Ch3  0.398
1988 Zaks A, Klibanov AM. The effect of water on enzyme action in organic media Journal of Biological Chemistry. 263: 8017-8021. PMID 3131337  0.387
1988 Russell AJ, Klibanov AM. Inhibitor-induced enzyme activation in organic solvents Journal of Biological Chemistry. 263: 11624-11626. PMID 3042774  0.382
1988 Weaver JC, Williams GB, Klibanov A, Demain AL. Gil microdroplets: Rapid detection and enumeration of individual microorganisms by their metabolic activity Bio/Technology. 6: 1084-1089. DOI: 10.1038/Nbt0988-1084  0.379
1988 Sakurai T, Margolin AL, Russell AJ, Klibanov AM. Control of enzyme enantioselectivity by the reaction medium Journal of the American Chemical Society. 110: 7236-7237. DOI: 10.1021/Ja00229A061  0.401
1988 Riva S, Klibanov AM. Enzymochemical regioselective oxidation of steroids without oxidoreductases Journal of the American Chemical Society. 110: 3291-3295. DOI: 10.1021/Ja00218A046  0.306
1988 Riva S, Chopineau J, Kieboom APG, Klibanov AM. Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamide Journal of the American Chemical Society. 110: 584-589. DOI: 10.1021/Ja00210A045  0.339
1988 Kitaguchi H, Tai D, Klibanov AM. Enzymatic formation of an isopeptide bond involving the ε-amino group of lysine Tetrahedron Letters. 29: 5487-5488. DOI: 10.1016/S0040-4039(00)80793-5  0.384
1988 MARGOLIN AL, TAI D, KLIBANOV AM. ChemInform Abstract: Incorporation of D-Amino Acids into Peptides via Enzymatic Condensation in Organic Solvents. Cheminform. 19. DOI: 10.1002/chin.198813316  0.25
1987 Dordick JS, Marletta MA, Klibanov AM. Polymerization of phenols catalyzed by peroxidase in nonaqueous media. Biotechnology and Bioengineering. 30: 31-6. PMID 18576580 DOI: 10.1002/Bit.260300106  0.423
1987 Zale SE, Klibanov AM. Why does ribonuclease irreversibly inactivate at high temperatures? Biochemistry. 25: 5432-44. PMID 3778869 DOI: 10.1021/Bi00367A014  0.413
1987 Casal JI, Ahern TJ, Davenport RC, Petsko GA, Klibanov AM. Subunit interface of triosephosphate isomerase: site-directed mutagenesis and characterization of the altered enzyme. Biochemistry. 26: 1258-64. PMID 3552044 DOI: 10.1021/Bi00379A009  0.436
1987 Ahern TJ, Casal JI, Petsko GA, Klibanov AM. Control of oligomeric enzyme thermostability by protein engineering. Proceedings of the National Academy of Sciences of the United States of America. 84: 675-9. PMID 3543933 DOI: 10.1073/Pnas.84.3.675  0.439
1987 Barzana E, Klibanov AM, Karel M. Enzyme-catalyzed, gas-phase reactions. Applied Biochemistry and Biotechnology. 15: 25-34. PMID 3310874 DOI: 10.1007/Bf02798504  0.405
1987 WILLIAMS GB, THREEFOOT SR, LORENZ JW, BLISS JG, WEAVER JC, DEMAIN AL, KLIBANOV AM. Rapid Detection of E. coli Immobilized in Gel Microdroplets Annals of the New York Academy of Sciences. 501: 350-353. PMID 3300501 DOI: 10.1111/J.1749-6632.1987.Tb45735.X  0.357
1987 KLIBANOV AM. Enzyme-Catalyzed Processes in Organic Solvents Annals of the New York Academy of Sciences. 501: 129-129. DOI: 10.1111/J.1749-6632.1987.Tb45697.X  0.442
1987 Margolin AL, Tai DF, Klibanov AM. Incorporation of D-amino acids into peptides via enzymic condensation in organic solvents Journal of the American Chemical Society. 109: 7885-7887. DOI: 10.1021/Ja00259A049  0.396
1987 Therisod M, Klibanov AM. Regioselective acylation of secondary hydroxyl groups in sugars catalyzed by lipases in organic solvents Journal of the American Chemical Society. 109: 3977-3981. DOI: 10.1021/Ja00247A024  0.399
1987 Margolin AL, Klibanov AM. Peptide synthesis catalyzed by lipases in anhydrous organic solvents Journal of the American Chemical Society. 109: 3802-3804. DOI: 10.1021/Ja00246A060  0.37
1987 Klibanov AM, Cambou B. [12] Enzymatic production of optically active compounds in biphasic aqueous-organic systems Methods in Enzymology. 136: 117-137. DOI: 10.1016/S0076-6879(87)36014-8  0.422
1987 Margolin AL, Crenne J, Klibanov AM. Stereoselective oligomerizations catalyzed by lipases in organic solvents Tetrahedron Letters. 28: 1607-1609. DOI: 10.1016/S0040-4039(00)95371-1  0.395
1987 THERISOD M, KLIBANOV AM. ChemInform Abstract: Regioselective Acylation of Secondary Hydroxyl Groups in Sugars Catalyzed by Lipases in Organic Solvents. Cheminform. 18. DOI: 10.1002/chin.198743329  0.3
1987 MARGOLIN AL, KLIBANOV AM. ChemInform Abstract: Peptide Synthesis Catalyzed by Lipases in Anhydrous Organic Solvents. Cheminform. 18. DOI: 10.1002/chin.198741334  0.266
1987 MARGOLIN AL, CRENNE J, KLIBANOV AM. ChemInform Abstract: Stereoselective Oligomerizations Catalyzed by Lipases in Organic Solvents. Cheminform. 18. DOI: 10.1002/chin.198739343  0.298
1987 GRUNWALD J, WIRZ B, SCOLLAR MP, KLIBANOV AM. ChemInform Abstract: Asymmetric Oxidoreductions Catalyzed by Alcohol Dehydrogenase in Organic Solvents. Cheminform. 18. DOI: 10.1002/chin.198710164  0.268
1987 THERISOD M, KLIBANOV AM. ChemInform Abstract: Facile Enzymatic Preparation of Monoacylated Sugars in Pyridine. Cheminform. 18. DOI: 10.1002/chin.198702316  0.27
1986 Sung C, Lavin A, Klibanov AM, Langer R. An immobilized enzyme reactor for the detoxification of bilirubin. Biotechnology and Bioengineering. 28: 1531-9. PMID 18553870 DOI: 10.1002/Bit.260281011  0.445
1986 Dordick JS, Klibanov AM, Marletta MA. Horseradish peroxidase catalyzed hydroxylations: Mechanistic studies Biochemistry. 25: 2946-2951. PMID 3718931 DOI: 10.1021/Bi00358A032  0.373
1986 Boeriu CG, Dordick JS, Klibanov AM. Enzymatic reactions in liquid and solid paraffins: Application for enzyme-based temperature abuse sensors Bio/Technology. 4: 997-999. DOI: 10.1038/Nbt1186-997  0.369
1986 Grunwald J, Wirz B, Scollar MP, Klibanov AM. Asymmetric oxidoreductions catalyzed by alcohol dehydrogenase in organic solvents Journal of the American Chemical Society. 108: 6732-6734. DOI: 10.1021/Ja00281A044  0.397
1986 Therisod M, Klibanov AM. Facile enzymatic preparation of monoacylated sugars in pyridine Journal of the American Chemical Society. 108: 5638-5640. DOI: 10.1021/Ja00278A053  0.39
1986 ZAKS A, KLIBANOV AM. ChemInform Abstract: Substrate Specificity of Enzymes in Organic Solvents vs. Water Is Reversed. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198637323  0.357
1986 Zaks A, Klibanov AM. Substrate specificity of enzymes in organic solvents vs. water is reversed Journal of the American Chemical Society. 108: 2767-2768. DOI: 10.1002/Chin.198637323  0.448
1986 KIRCHNER G, SCOLLAR MP, KLIBANOV AM. ChemInform Abstract: Resolution of Racemic Mixtures via Lipase Catalysis in Organic Solvents. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198612109  0.289
1985 Zale SE, Klibanov AM. Mechanisms of irreversible thermoinactivation of enzymes. Annals of the New York Academy of Sciences. 434: 20-6. PMID 6596896 DOI: 10.1111/J.1749-6632.1984.Tb29794.X  0.423
1985 Lavin A, Sung C, Klibanov AM, Langer R. Enzymatic removal of bilirubin from blood: a potential treatment for neonatal jaundice. Science (New York, N.Y.). 230: 543-5. PMID 4048947 DOI: 10.1126/Science.4048947  0.349
1985 Ahern TJ, Klibanov AM. The mechanisms of irreversible enzyme inactivation at 100C. Science (New York, N.Y.). 228: 1280-4. PMID 4001942 DOI: 10.1126/science.4001942  0.32
1985 Zaks A, Klibanov AM. Enzyme-catalyzed processes in organic solvents. Proceedings of the National Academy of Sciences of the United States of America. 82: 3192-6. PMID 3858815 DOI: 10.1073/Pnas.82.10.3192  0.455
1985 Cesti P, Zaks A, Klibanov AM. Preparative regioselective acylation of glycols by enzymatic transesterification in organic solvents Applied Biochemistry and Biotechnology. 11: 401-407. DOI: 10.1007/Bf02798673  0.423
1985 Hammond DA, Karel M, Klibanov AM, Krukonis VJ. Enzymatic reactions in supercritical gases Applied Biochemistry and Biotechnology. 11: 393-400. DOI: 10.1007/Bf02798672  0.404
1985 Kirchner G, Scollar MP, Klibanov AM. Resolution of racemic mixtures via lipase catalysis in organic solvents Journal of the American Chemical Society. 107: 7072-7076. DOI: 10.1002/Chin.198612109  0.391
1985 KAZANDJIAN RZ, KLIBANOV AM. ChemInform Abstract: REGIOSELECTIVE OXIDATION OF PHENOLS CATALYZED BY POLYPHENOL OXIDASE IN CHLOROFORM Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198552146  0.232
1985 Kazandjian RZ, Klibanov AM. Regioselective oxidation of phenols catalyzed by polyphenol oxidase in chloroform Journal of the American Chemical Society. 107: 5448-5450. DOI: 10.1002/Chin.198552146  0.338
1984 Zaks A, Klibanov AM. Enzymatic catalysis in organic media at 100 degrees C. Science (New York, N.Y.). 224: 1249-51. PMID 6729453 DOI: 10.1126/Science.6729453  0.432
1984 Klibanov AM. Stabilization of enzymes against thermal inactivation. Advances in Applied Microbiology. 29: 1-28. PMID 6650260 DOI: 10.1016/S0065-2164(08)70352-6  0.452
1984 Lavin A, Sung C, Klibanov A, Langer R. DEVELOPMENT OF AN IMMOBILIZED ENZYME REACTOR FOR THE TREATMENT OF HYPERBILIRUBINEMIA Pediatric Research. 18: 155A-155A. DOI: 10.1203/00006450-198404001-00374  0.43
1984 WEAVER JC, SEISSLER PE, THREEFOOT SA, LORENZ JW, HUIE T, RODRIGUEZ R, KLIBANOV AM. Microbiological Measurements by Immobilization of Cells within Small-Volume Elements Annals of the New York Academy of Sciences. 434: 363-372. DOI: 10.1111/J.1749-6632.1984.Tb29858.X  0.317
1984 Cambou B, Klibanov AM. Preparative production of optically active esters and alcohols using esterase-catalyzed stereospecific transesterification in organic media Journal of the American Chemical Society. 106: 2687-2692. DOI: 10.1021/Ja00321A033  0.361
1984 Cambou B, Klibanov AM. Lipase-catalyzed production of optically active acids via asymmetric hydrolysis of esters Applied Biochemistry and Biotechnology. 9: 255-260. DOI: 10.1007/Bf02798491  0.409
1984 CAMBOU B, KLIBANOV AM. Unusual Catalytic Properties of Usual Enzymes Annals of the New York Academy of Sciences. 434: 219-223. DOI: 10.1002/Chin.198437326  0.426
1984 KLIBANOV AM. ChemInform Abstract: Unusual Catalytic Properties of Usual Enzymes Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198437326  0.332
1984 CAMBOU B, KLIBANOV AM. ChemInform Abstract: PREPARATIVE PRODUCTION OF OPTICALLY ACTIVE ESTERS AND ALCOHOLS USING ESTERASE-CATALYZED STEREOSPECIFIC TRANSESTERIFICATION IN ORGANIC MEDIA Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198433086  0.256
1983 Klibanov AM, Alberti BN, Marletta MA. Stereospecific oxidation of aliphatic alcohols catalyzed by galactose oxidase. Biochemical and Biophysical Research Communications. 108: 804-8. PMID 7150324 DOI: 10.1016/0006-291X(82)90900-7  0.385
1983 Klibanov AM. Approaches to enzyme stabilization. Biochemical Society Transactions. 11: 19-20. PMID 6337884 DOI: 10.1042/Bst0110019  0.414
1983 Pelsy G, Klibanov AM. Remarkable positional (regio)specificity of xanthine oxidase and some dehydrogenases in the reactions with substituted benzaldehydes. Biochimica Et Biophysica Acta. 742: 352-7. PMID 6337634 DOI: 10.1016/0167-4838(83)90321-7  0.417
1983 Klibanov AM, Chendrasekhar A, Alberti BN. Enzymatic separation of cis and trans isomers of alicyclic alcohols Enzyme and Microbial Technology. 5: 265-268. DOI: 10.1016/0141-0229(83)90075-3  0.36
1982 Klibanov AM, Giannousis PP. Geometric specificity of alcohol dehydrogenases and its potential for separation of trans and cis isomers of unsaturated aldehydes. Proceedings of the National Academy of Sciences of the United States of America. 79: 3462-5. PMID 7048306 DOI: 10.1073/pnas.79.11.3462  0.244
1982 Klibanov AM, Siegel EH. Geometric specificity of porcine liver carboxylesterase and its application for the production of cis-arylacrylic esters Enzyme and Microbial Technology. 4: 172-174. DOI: 10.1016/0141-0229(82)90112-0  0.352
1982 Alberti BN, Klibanov AM. Preparative production of hydroquinone from benzoquinone catalysed by immobilized d-glucose oxidase Enzyme and Microbial Technology. 4: 47-49. DOI: 10.1016/0141-0229(82)90011-4  0.341
1982 Klibanov AM, Giannousis PP. Geometrically specific oxidation of ?-arylacroleins catalyzed by xanthine oxidase: The preparative potential Biotechnology Letters. 4: 57-60. DOI: 10.1007/Bf00139283  0.376
1982 Pungor E, Klibanov AM, Cooney CL, Weaver JC. Continuous2HHO determination in H2O solution by a computer-controlled mass spectrometer Biological Mass Spectrometry. 9: 181-185. DOI: 10.1002/Bms.1200090502  0.363
1981 Khan SM, Klibanov AM, Kaplan NO, Kamen MD. The effect of electron carriers and other ligands on oxygen stability of clostridial hydrogenase. Biochimica Et Biophysica Acta. 659: 457-65. PMID 7020766 DOI: 10.1016/0005-2744(81)90071-1  0.656
1981 Klibanov AM, Berman Z, Alberti BN. Preparative hydroxylation of aromatic compounds catalyzed by peroxidase Journal of the American Chemical Society. 103: 6263-6264. DOI: 10.1021/Ja00410A067  0.35
1981 Klibanov AM, Morris ED. Horseradish peroxidase for the removal of carcinogenic aromatic amines from water Enzyme and Microbial Technology. 3: 119-122. DOI: 10.1016/0141-0229(81)90069-7  0.413
1981 Sharma BP, Klibanov AM. Book reviews Applied Biochemistry and Biotechnology. 6: 79-82. DOI: 10.1007/BF02779689  0.164
1981 Klibanov AM, Huber J. Application of immobilized hydrogenase for the detritiation of water Biotechnology and Bioengineering. 23: 1537-1551. DOI: 10.1002/Bit.260230713  0.407
1980 Klibanov AM, Kaplan NO, Kamen MD. Thermal stabilities of membrane-bound, solubilized, and artificially immobilized hydrogenase from Chromatium vinosum. Archives of Biochemistry and Biophysics. 199: 545-9. PMID 7362243 DOI: 10.1016/0003-9861(80)90312-4  0.667
1980 Klibanov AM, Puglisi AV. The regeneration of coenzymes using immobilized hydrogenase Biotechnology Letters. 2: 445-450. DOI: 10.1007/Bf00162353  0.384
1979 Torchilin VP, Maksimenko AV, Smirnov VN, Berezin IV, Klibanov AM, Martinek K. The principles of enzyme stabilization. IV. Modification of 'key' functional groups in the tertiary structure of proteins. Biochimica Et Biophysica Acta. 567: 1-11. PMID 454615 DOI: 10.1016/0005-2744(79)90165-7  0.715
1979 Klibanov AM, Kaplan NO, Kamen MD. Chelating agents protect hydrogenase against oxygen inactivation. Biochimica Et Biophysica Acta. 547: 411-6. PMID 111712 DOI: 10.1016/0005-2728(79)90021-5  0.663
1979 Klibanov AM. Enzyme stabilization by immobilization Analytical Biochemistry. 93: 1-25. DOI: 10.1016/S0003-2697(79)80110-4  0.431
1978 Klibanov AM, Mozhaev VV. On the mechanism of irreversible thermoinactivation of enzymes and possibilities for reactivation of "irreversibly" inactivated enzymes. Biochemical and Biophysical Research Communications. 83: 1012-7. PMID 708419 DOI: 10.1016/0006-291X(78)91496-1  0.455
1978 Torchilin VP, Maksimenko AV, Smirnov VN, Berezin IV, Klibanov AM, Martinek K. The principles of enzyme stabilization. III. The effect of the length of intra-molecular cross-linkages on thermostability of enzymes. Biochimica Et Biophysica Acta. 522: 277-83. PMID 623767 DOI: 10.1016/0005-2744(78)90061-X  0.71
1978 Klibanov AM, Kaplan NO, Kamen MD. A rationale for stabilization of oxygen-labile enzymes: application to a clostridial hydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 75: 3640-3. PMID 278979 DOI: 10.1073/Pnas.75.8.3640  0.689
1978 Poglazov BF, Samokhin GP, Klibanov AM, Levitsky DI, Martinek K, Berezin IV. The effect of mechanical stretching of the myosin rod component (fragment LMMMM S-2) on the ATPase activity of myosin. Biochimica Et Biophysica Acta. 524: 245-53. PMID 149560 DOI: 10.1016/0005-2744(78)90161-4  0.676
1977 Berezin IV, Klibanov AM, Goldmacher VS, Martinek K. Mechanochemistry of immobilized enzymes: a new approach to studies in fundamental enzymology. II. Regulation of the rate of enzymic protein-protein interaction in polyacrylamide gel. Methods in Enzymology. 44: 571-6. PMID 1021696 DOI: 10.1016/S0076-6879(76)44042-9  0.698
1977 Berezin IV, Klibanov AM, Samokhin GP, Martinek K. Mechanochemistry of immobilized enzymes: a new approach to studies in fundamental enzymology. I. Regulation by mechanical means of the catalytic properties of enzymes attached to polymer fibers. Methods in Enzymology. 44: 558-71. PMID 1021695 DOI: 10.1016/S0076-6879(76)44041-7  0.695
1977 Martinek K, Klibanov AM, Goldmacher VS, Tchernysheva AV, Mozhaev VV, Berezin IV, Glotov BO. The principles of enzyme stabilization. II. Increase in the thermostability of enzymes as a result of multipoint noncovalent interaction with a polymeric support. Biochimica Et Biophysica Acta. 485: 13-28. PMID 911858 DOI: 10.1016/0005-2744(77)90189-9  0.699
1977 Martinek K, Klibanov AM, Goldmacher VS, Berezin IV. The principles of enzyme stabilization. I. Increase in thermostability of enzymes covalently bound to a complementary surface of a polymer support in a multipoint fashion. Biochimica Et Biophysica Acta. 485: 1-12. PMID 911857 DOI: 10.1016/0005-2744(77)90188-7  0.705
1977 Klibanov AM, Samokhin GP, Martinek K, Berezin IV. A new mechanochemical method of enzyme immobilization. Biotechnology and Bioengineering. 19: 211-8. PMID 851589 DOI: 10.1002/bit.260190205  0.305
1976 Klibanov AM, Samokhin GP, Martinek K, Berezin IV. Enzymatic mechanochemistry: a new approach to studying the mechanism of enzyme action. Biochimica Et Biophysica Acta. 438: 1-12. PMID 938678 DOI: 10.1016/0005-2744(76)90218-7  0.717
1975 Berezin IV, Klibanov AM, Martinek K. The mechanochemistry of immobilized enzymes. How to steer a chemical process at the molecular level by a mechanical device. Biochimica Et Biophysica Acta. 364: 193-9. PMID 4422092 DOI: 10.1016/0005-2744(74)90003-5  0.717
1975 Martinek K, Goldmacher VS, Klibanov AM, Berezin IV. Denaturing agents (urea, acrylamide) protect enzymes against irreversible thermoinactivation: a study with native and immobilized alpha-chymotrypsin and trypsin. Febs Letters. 51: 152-5. PMID 1168150 DOI: 10.1016/0014-5793(75)80874-X  0.692
1975 Berezin IV, Klibanov AM, Klyosov AA, Martinek K, Svedas VK. The effect of ultrasound as a new method of studying conformational transitions in enzyme active sites. pH- and temperature-induced conformational transitions in the active centre of penicillin amidase. Febs Letters. 49: 325-8. PMID 234079 DOI: 10.1016/0014-5793(75)80777-0  0.683
1975 Berezin IV, Klibanov AM, Martinek K. Kinetic and Thermodynamic Aspects of Catalysis by Immobilised Enzymes Russian Chemical Reviews. 44: 9-25. DOI: 10.1070/RC1975v044n01ABEH002141  0.7
1975 Chernysheva AV, Marinek K, Klibanov AM, Mevkh AT, Berezin IV. Catalytic properties and thermal stability of?-chymotrypsin in polyelectrolyte gels based on methacrylate Bulletin of the Academy of Sciences of the Ussr Division of Chemical Science. 24: 1648-1652. DOI: 10.1007/BF01100013  0.671
1974 Berezin IV, Varfolomeyev SD, Klibanov AM, Martinek K. Light and ultrasonic regulation of alpha-chymotrypsin catalytic activity. Proflavin as a light- and sound-sensitive competitive inhibitor. Febs Letters. 39: 329-31. PMID 4852994 DOI: 10.1016/0014-5793(74)80142-0  0.652
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