Year |
Citation |
Score |
2011 |
Valentine WJ, Godwin VI, Osborne DA, Liu J, Fujiwara Y, Van Brocklyn J, Bittman R, Parrill AL, Tigyi G. FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain 2. The Journal of Biological Chemistry. 286: 30513-25. PMID 21719706 DOI: 10.1074/Jbc.M111.263442 |
0.679 |
|
2009 |
North EJ, Osborne DA, Bridson PK, Baker DL, Parrill AL. Autotaxin structure-activity relationships revealed through lysophosphatidylcholine analogs. Bioorganic & Medicinal Chemistry. 17: 3433-42. PMID 19345587 DOI: 10.1016/J.Bmc.2009.03.030 |
0.549 |
|
2008 |
Fells JI, Tsukahara R, Fujiwara Y, Liu J, Perygin DH, Osborne DA, Tigyi G, Parrill AL. Identification of non-lipid LPA3 antagonists by virtual screening. Bioorganic & Medicinal Chemistry. 16: 6207-17. PMID 18467108 DOI: 10.1016/J.Bmc.2008.04.035 |
0.521 |
|
2008 |
Pham TC, Fells JI, Osborne DA, North EJ, Naor MM, Parrill AL. Molecular recognition in the sphingosine 1-phosphate receptor family. Journal of Molecular Graphics & Modelling. 26: 1189-201. PMID 18165127 DOI: 10.1016/J.Jmgm.2007.11.001 |
0.698 |
|
2007 |
Fujiwara Y, Osborne DA, Walker MD, Wang DA, Bautista DA, Liliom K, Van Brocklyn JR, Parrill AL, Tigyi G. Identification of the hydrophobic ligand binding pocket of the S1P1 receptor. The Journal of Biological Chemistry. 282: 2374-85. PMID 17114791 DOI: 10.1074/Jbc.M609648200 |
0.668 |
|
2005 |
Jo E, Sanna MG, Gonzalez-Cabrera PJ, Thangada S, Tigyi G, Osborne DA, Hla T, Parrill AL, Rosen H. S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chemistry & Biology. 12: 703-15. PMID 15975516 DOI: 10.1016/J.Chembiol.2005.04.019 |
0.694 |
|
2005 |
Inagaki Y, Pham TT, Fujiwara Y, Kohno T, Osborne DA, Igarashi Y, Tigyi G, Parrill AL. Sphingosine 1-phosphate analogue recognition and selectivity at S1P4 within the endothelial differentiation gene family of receptors. The Biochemical Journal. 389: 187-95. PMID 15733055 DOI: 10.1042/BJ20050046 |
0.677 |
|
2004 |
Holdsworth G, Osborne DA, Pham TT, Fells JI, Hutchinson G, Milligan G, Parrill AL. A single amino acid determines preference between phospholipids and reveals length restriction for activation of the S1P4 receptor. Bmc Biochemistry. 5: 12. PMID 15298705 DOI: 10.1186/1471-2091-5-12 |
0.737 |
|
2000 |
Osborne DA, Dreher WR, Gore HR, Stoddard A, Valente EJ. Racemic and (+)-ethyl 2-acetamido-2-carboxy-5-oxohexanoate Journal of Chemical Crystallography. 30: 583-588. DOI: 10.1023/A:1011306310249 |
0.444 |
|
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