Jennifer Rachel Cochran

Bioengineering Stanford University, Palo Alto, CA 
"Jennifer Rachel Cochran"

Cross-listing: Neurotree


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Lawrence J. Stern grad student 2001 MIT (Chemistry Tree)
 (The molecular mechanism of T cell activation investigated with class II MHC oligomers.)
K. Dane Wittrup post-doc 2002-2004 MIT (Chemistry Tree)
William F. DeGrado post-doc 2004-2005 UCSF (Chemistry Tree)


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Ping-Chuan (Christina) Tsai post-doc 2010-2012 Stanford Medical School (Chemistry Tree)
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Silberstein JL, Du J, Chan KW, et al. (2024) Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function. Proceedings of the National Academy of Sciences of the United States of America. 121: e2310866121
Murty S, Labanieh L, Murty T, et al. (2020) PET reporter gene imaging and ganciclovir-mediated ablation of chimeric antigen receptor T-cells in solid tumors. Cancer Research
Mehta N, Maddineni S, Kelly RL, et al. (2020) An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA. Scientific Reports. 10: 15171
Kim JW, Marquez CP, Sperberg RAP, et al. (2020) Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand. Proceedings of the National Academy of Sciences of the United States of America
Kim JW, Marquez CP, Kostyrko K, et al. (2019) Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma. Nature Medicine
Mehta N, Maddineni S, Mathews II, et al. (2019) Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation. Cell Reports. 28: 2509-2516.e5
Van Agthoven JF, Shams H, Cochran FV, et al. (2019) Structural Basis of the Differential Binding of Engineered Knottins to Integrins αVβ3 and α5β1. Structure (London, England : 1993)
Mitchell AC, Kannan D, Hunter SA, et al. (2018) Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein. The Journal of Biological Chemistry
Marquez C, Kim J, Giaccia A, et al. (2018) Abstract 3918: Targeting the CLCF1-CNTFR signaling axis using directed evolution for lung cancer therapy Cancer Research. 78: 3918-3918
Thayaparan T, Petrovic RM, Achkova DY, et al. (2017) CAR T-cell immunotherapy of MET-expressing malignant mesothelioma. Oncoimmunology. 6: e1363137
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