Serena D. Webb, Ph.D.

Affiliations: 
2001 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Chemical Engineering, Pharmaceutical Chemistry
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"Serena Webb"

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Theodore W. Randolph grad student 2001 CU Boulder
 (Reconstitution of lyophilized therapeutic protein: Effects of formulation, processing techniques and surfaces.)
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Publications

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Webb SD, Cleland JL, Carpenter JF, et al. (2003) Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma. Journal of Pharmaceutical Sciences. 92: 715-29
Webb SD, Golledge SL, Cleland JL, et al. (2002) Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations. Journal of Pharmaceutical Sciences. 91: 1474-87
Webb SD, Cleland JL, Carpenter JF, et al. (2002) A new mechanism for decreasing aggregation of recombinant human interferon-gamma by a surfactant: slowed dissolution of lyophilized formulations in a solution containing 0.03% polysorbate 20. Journal of Pharmaceutical Sciences. 91: 543-58
Webb SD, Webb JN, Hughes TG, et al. (2002) Freezing bulk-scale biopharmaceuticals using common techniques - And the magnitude of freeze-concentration Biopharm. 15: 22-34
Webb SD, Koval CA, Randolph CM, et al. (2001) Electrochemical determination of dissolution rates of lyophilized pharmaceutical formulations. Analytical Chemistry. 73: 5296-301
Webb JN, Webb SD, Cleland JL, et al. (2001) Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: high-pressure and cosolute studies on recombinant human IFN-gamma. Proceedings of the National Academy of Sciences of the United States of America. 98: 7259-64
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