Jun Nakamura

Affiliations: 
Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Environmental Sciences, Molecular Biology, Toxicology
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"Jun Nakamura"
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Publications

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Nakamura J. (2020) Potential doxorubicin-mediated dual-targeting chemotherapy in FANC/BRCA-deficient tumors via modulation of cellular formaldehyde concentration. Chemical Research in Toxicology
Nakamura J, Holley DW, Kawamoto T, et al. (2020) The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 42: 21
Nakamura J, Nakamura M. (2020) DNA-protein crosslink formation by endogenous aldehydes and AP sites. Dna Repair. 88: 102806
Ridpath JR, Nakamura J. (2019) Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancer. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 41: 23
Saha LK, Kim S, Kang H, et al. (2018) Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Environmental and Molecular Mutagenesis
Tsuda M, Cho K, Ooka M, et al. (2017) ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. Plos One. 12: e0188320
De La Rosa VY, Asfaha J, Fasullo M, et al. (2017) High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes. Toxicological Sciences : An Official Journal of the Society of Toxicology
Tian X, Patel K, Ridpath JR, et al. (2016) Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. Plos One. 11: e0167503
Hashimoto K, Sharma V, Sasanuma H, et al. (2016) Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget
Sharma V, Collins LB, Chen TH, et al. (2016) Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget
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