David Needham

Mechanical Engineering and Materials Science Duke University, Durham, NC 
Materials Science Engineering, General Biophysics
"David Needham"


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Daniel Douglas Eley grad student 1977-1981 Nottingham (Chemistry Tree)


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Phillip B. Duncan grad student 2005 Duke
Deborah L. Rickard grad student 2011 Duke
Jonathan T. Su grad student 2011 Duke
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Aniket, Gaul DA, Bitterfield DL, et al. (2015) Enzyme dehydration using Microglassification™ preserves the protein's structure and function. Journal of Pharmaceutical Sciences. 104: 640-51
Zagar TM, Vujaskovic Z, Formenti S, et al. (2014) Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 30: 285-94
Bagatolli LA, Needham D. (2014) Quantitative optical microscopy and micromanipulation studies on the lipid bilayer membranes of giant unilamellar vesicles. Chemistry and Physics of Lipids. 181: 99-120
Aniket, Gaul DA, Rickard DL, et al. (2014) Microglassification™: a novel technique for protein dehydration. Journal of Pharmaceutical Sciences. 103: 810-20
Su JT, Needham D. (2013) Mass transfer in the dissolution of a multicomponent liquid droplet in an immiscible liquid environment. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 13339-45
Needham D, Park JY, Wright AM, et al. (2013) Materials characterization of the low temperature sensitive liposome (LTSL): effects of the lipid composition (lysolipid and DSPE-PEG2000) on the thermal transition and release of doxorubicin. Faraday Discussions. 161: 515-34; discussion 5
Needham D. (2013) Reverse engineering of the low temperature-sensitive liposome (LTSL) for treating cancer Biomaterials For Cancer Therapeutics: Diagnosis, Prevention and Therapy. 270-348
Needham D, Dewhirst MW. (2013) Materials science and engineering of the low temperature sensitive liposome (LTSL): Composition-structure-property relationships that underlie its design and performance Rsc Smart Materials. 1: 33-79
Manzoor AA, Lindner LH, Landon CD, et al. (2012) Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Research. 72: 5566-75
Gilchrist SE, Rickard DL, Letchford K, et al. (2012) Phase separation behavior of fusidic acid and rifampicin in PLGA microspheres. Molecular Pharmaceutics. 9: 1489-501
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