Andrea N. Naranjo, Ph.D.

2014 Department of Chemical Engineering University of Delaware, Newark, DE, United States 
Chemical Engineering, General Biophysics, Biochemistry
"Andrea Naranjo"


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Anne Skaja Robinson grad student 2014 University of Delaware
 (Stability and activity of a GPCR in vivo and in membrane mimetic environments.)
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McNeely PM, Naranjo AN, Forsten-Williams K, et al. (2016) A2AR Binding Kinetics in the Ligand Depletion Regime. Journal of Biomolecular Screening
Naranjo AN, McNeely PM, Katsaras J, et al. (2016) Impact of purification conditions and history on A2A adenosine receptor activity: The role of CHAPS and lipids. Protein Expression and Purification
Blocker KM, Britton ZT, Naranjo AN, et al. (2015) Recombinant G protein-coupled receptor expression in Saccharomyces cerevisiae for protein characterization. Methods in Enzymology. 556: 165-83
Naranjo AN, Chevalier A, Cousins GD, et al. (2015) Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition. Biochimica Et Biophysica Acta. 1848: 603-14
Naranjo AN, Katsaras J, Robinson AS. (2014) Short Chain Lipids Maintain Adenosine A2AR Ligand Binding in the Absence of Cholesterol Biophysical Journal. 106: 518a
Naranjo AN, Katsaras J, Robinson AS. (2013) Short Hydrocarbon Chain Lipids Enable Class a G Protein-Coupled Receptor Isolation in its Active Conformation: Eliminating the Need for Detergents Biophysical Journal. 104: 42a
McNeely PM, Naranjo AN, Robinson AS. (2012) Structure-function studies with G protein-coupled receptors as a paradigm for improving drug discovery and development of therapeutics. Biotechnology Journal. 7: 1451-61
Sahin E, Jordan JL, Spatara ML, et al. (2011) Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity. Biochemistry. 50: 628-39
Naranjo AN, O'Malley MA, Chavalier AN, et al. (2011) Exploring the Trafficking, Ligand-Binding Activity, and Unfolding of a Model GPCR Biophysical Journal. 100: 516a
O'Malley MA, Naranjo AN, Lazarova T, et al. (2010) Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds. Biochemistry. 49: 9181-9
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