Janna K. Mouw, Ph.D.

Affiliations: 
2005 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Cell Biology
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"Janna Mouw"

Parents

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Marc E. Levenston grad student 2005 Georgia Tech
 (Mechanoregulation of chondrocytes and chondroprogenitors: The role of TGF-beta and Smad signaling.)
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Publications

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Laklai H, Miroshnikova YA, Pickup MW, et al. (2016) Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine
Le LT, Cazares O, Mouw JK, et al. (2016) Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. The Journal of Cell Biology. 212: 707-19
Pickup MW, Mouw JK, Weaver VM. (2014) The extracellular matrix modulates the hallmarks of cancer. Embo Reports. 15: 1243-53
Mouw JK, Ou G, Weaver VM. (2014) Extracellular matrix assembly: a multiscale deconstruction. Nature Reviews. Molecular Cell Biology. 15: 771-85
Paszek MJ, DuFort CC, Rossier O, et al. (2014) The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 511: 319-25
Mouw JK, Yui Y, Damiano L, et al. (2014) Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nature Medicine. 20: 360-7
Damiano L, Stewart KM, Cohet N, et al. (2014) Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin. Oncogene. 33: 2441-53
Yu H, Mouw JK, Weaver VM. (2011) Forcing form and function: biomechanical regulation of tumor evolution. Trends in Cell Biology. 21: 47-56
Gilbert PM, Mouw JK, Unger MA, et al. (2010) HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. The Journal of Clinical Investigation. 120: 1535-50
Connelly JT, Vanderploeg EJ, Mouw JK, et al. (2010) Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs. Tissue Engineering. Part A. 16: 1913-23
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