Jacques de Champlain

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Biomedical Engineering, Cell Biology
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"Jacques de Champlain"
Bio:

https://escholarship.mcgill.ca/concern/theses/7m01bq04s

Parents

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Jacques Genest grad student 1965 McGill (Medicine Tree)
 (Studies on renin-angiotensin system in various human and physiological and pathological states.)
Julius Axelrod post-doc 1966 NIMH (Neurotree)

Children

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Hélène Girouard grad student Université de Montréal (Neurotree)
Michel Bouvier grad student 1979-1984 Université de Montréal (Neurotree)
Chantal Chulak grad student 2003 Université de Montréal
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Publications

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Wu R, Yin D, Sadekova N, et al. (2012) Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters. Oxidative Medicine and Cellular Longevity. 2012: 761710
Wu R, Duchemin S, Laplante MA, et al. (2011) Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension. American Journal of Hypertension. 24: 1239-44
El Midaoui A, Ismael MA, Lu H, et al. (2008) Comparative effects of N-acetyl-L-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats. Canadian Journal of Physiology and Pharmacology. 86: 752-60
Lalaoui MZ, El Midaoui A, de Champlain J, et al. (2007) Is there a role for reactive oxygen species in arterial medial elastocalcinosis? Vascular Pharmacology. 46: 201-6
El Midaoui A, Wu L, Wang R, et al. (2006) Modulation of cardiac and aortic peroxisome proliferator-activated receptor-gamma expression by oxidative stress in chronically glucose-fed rats. American Journal of Hypertension. 19: 407-12
Petcu M, Ongali B, El Midaoui A, et al. (2005) Effects of alpha-lipoic acid on kinin B1 and B2 receptor binding sites in the spinal cord of chronically angiotensin-treated rats. Peptides. 26: 1331-8
Wu R, Laplante MA, de Champlain J. (2005) Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. Hypertension. 45: 1139-44
Girouard H, de Champlain J. (2005) Acute and chronic effects of free radicals on alpha1-adrenergic-induced vasoconstriction in mesenteric beds of spontaneously hypertensive rats. Journal of Hypertension. 23: 807-14
de Champlain J, Wu R, Girouard H, et al. (2004) Oxidative stress in hypertension. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 26: 593-601
Girouard H, Denault C, Chulak C, et al. (2004) Treatment by n-acetylcysteine and melatonin increases cardiac baroreflex and improves antioxidant reserve. American Journal of Hypertension. 17: 947-54
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