Michael B. Simmers, Ph.D.

Affiliations: 
2010 University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering
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"Michael Simmers"

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Brett R. Blackman grad student 2010 UVA
 (Hemodynamic regulation of endothelial permeability and migration.)
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Publications

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Collado MS, Cole BK, Figler RA, et al. (2017) Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. Stem Cells Translational Medicine
Simmers MB, Cole BK, Ogletree ML, et al. (2016) Hemodynamics associated with atrial fibrillation directly alters thrombotic potential of endothelial cells. Thrombosis Research. 143: 34-39
Chapman KA, Collado MS, Figler RA, et al. (2015) Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes. Molecular Genetics and Metabolism
Cole BK, Simmers MB, Feaver R, et al. (2015) An In Vitro Cynomolgus Vascular Surrogate System for Preclinical Drug Assessment and Human Translation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2185-95
Dash A, Simmers MB, Deering TG, et al. (2013) Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro. American Journal of Physiology. Cell Physiology. 304: C1053-63
Hastings NE, Simmers MB, McDonald OG, et al. (2007) Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming. American Journal of Physiology. Cell Physiology. 293: C1824-33
Simmers MB, Pryor AW, Blackman BR. (2007) Arterial shear stress regulates endothelial cell-directed migration, polarity, and morphology in confluent monolayers. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1937-46
Orr AW, Stockton R, Simmers MB, et al. (2007) Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. The Journal of Cell Biology. 176: 719-27
Orr AW, Stockton R, Simmers M, et al. (2007) Matrix‐specific PAK activation regulates vascular permeability in atherosclerosis The Faseb Journal. 21
Orr AW, Stockton R, Simmers MB, et al. (2007) Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis The Journal of Experimental Medicine. 204: i7-i7
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