Michael A. Meledeo, Ph.D.

2009 Johns Hopkins University, Baltimore, MD 
Biomedical Engineering, Cell Biology, Molecular Biology
"Michael Meledeo"


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Kevin J. Yarema grad student 2009 Johns Hopkins
 (SCFA-hexosamines: Understanding anti-cancer mechanisms through chemical biology and molecular modeling.)
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Reddoch KM, Montgomery RK, Rodriguez AC, et al. (2015) Endothelium-Derived Inhibitors Efficiently Attenuate the Aggregation and Adhesion Responses of Refrigerated Platelets. Shock (Augusta, Ga.)
Meledeo MA, Campbell JE, Rodriguez AC, et al. (2015) Both acute delivery of and storage with magnesium sulfate promote cold-stored platelet aggregation and coagulation function. The Journal of Trauma and Acute Care Surgery. 79: S139-45
Campbell JE, Meledeo MA, Cap AP. (2014) Comparative response of platelet fV and plasma fV to activated protein C and relevance to a model of acute traumatic coagulopathy Plos One. 9
Meledeo MA, Paruchuri VDP, Du J, et al. (2011) Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition Carbohydrate Recognition: Biological Problems, Methods, and Applications. 1-32
Aich U, Meledeo MA, Sampathkumar SG, et al. (2010) Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconjugate Journal. 27: 445-59
Wang Z, Du J, Che PL, et al. (2009) Hexosamine analogs: from metabolic glycoengineering to drug discovery Current Opinion in Chemical Biology. 13: 565-572
Du J, Meledeo MA, Wang Z, et al. (2009) Metabolic glycoengineering: sialic acid and beyond. Glycobiology. 19: 1382-401
Elmouelhi N, Aich U, Paruchuri VD, et al. (2009) Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery. Journal of Medicinal Chemistry. 52: 2515-30
Atukorale PU, Choi SS, Aich U, et al. (2009) Chemical Biology of Cell Surface Oligosaccharides Protein Targeting With Small Molecules: Chemical Biology Techniques and Applications. 189-222
Sampathkumar SG, Jones MB, Meledeo MA, et al. (2006) Targeting glycosylation pathways and the cell cycle: sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. Chemistry & Biology. 13: 1265-75
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