Clara Abraham

Affiliations: 
Yale School of Medicine Yale University, New Haven, CT 
Area:
Biomedical Engineering, Immunology
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"Clara Abraham"
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Publications

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Verstockt B, Salas A, Sands BE, et al. (2023) IL-12 and IL-23 pathway inhibition in inflammatory bowel disease. Nature Reviews. Gastroenterology & Hepatology
Abraham C, Abreu MT, Turner JR. (2022) Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease. Gastroenterology
Ranjan K, Hedl M, Sinha S, et al. (2021) Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. The Journal of Clinical Investigation. 131
Ranjan K, Hedl M, Abraham C. (2021) The E3 ubiquitin ligase RNF186 and risk variants regulate innate receptor-induced outcomes. Proceedings of the National Academy of Sciences of the United States of America. 118
Sun R, Hedl M, Abraham C. (2020) TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and these are Modulated by TNFSF15 Disease-Risk Variants. Cellular and Molecular Gastroenterology and Hepatology
Kang JW, Yan J, Ranjan K, et al. (2020) Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology
Yan J, Hedl M, Abraham C. (2020) Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions. Journal of Immunology (Baltimore, Md. : 1950)
Hedl M, Sun R, Abraham C. (2020) Disease Risk-Associated Genetic Variants in and Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950)
Yan J, Pandey SP, Barnes BJ, et al. (2020) T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Reports. 31: 107820
Sun R, Abraham C. (2020) IL23 promotes antimicrobial pathways in human macrophages which are reduced with the IBD-protective IL23R R381Q variant. Cellular and Molecular Gastroenterology and Hepatology
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