Michael C. Williams

Chemical and Biological Engineering Chemical Engineering 
"Michael Williams"
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James J, Ruggeri B, Armstrong RC, et al. (2012) CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity. Molecular Cancer Therapeutics. 11: 930-41
Rowbottom MW, Faraoni R, Chao Q, et al. (2012) Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E. Journal of Medicinal Chemistry. 55: 1082-105
Holladay MW, Campbell BT, Rowbottom MW, et al. (2011) 4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 5342-6
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