| Year |
Citation |
Score |
| 2023 |
Cheng X, Caruso C, Lam WA, Graham MD. Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders. Science Advances. 9: eadj6423. PMID 38019922 DOI: 10.1126/sciadv.adj6423 |
0.308 |
|
| 2023 |
Raj A, Ramirez K, Young KM, Stone N, Shankles P, Ali MNR, Compton AM, Lam W, Alexeev A, Sulchek T. Label-free microfluidic isolation of functional and viable lymphocytes from peripheral blood mononuclear cells. Biomicrofluidics. 17: 054102. PMID 37736019 DOI: 10.1063/5.0161047 |
0.328 |
|
| 2023 |
Sun Y, Le H, Lam WA, Alexeev A. Probing interactions of red blood cells and contracting fibrin platelet clots. Biophysical Journal. PMID 37598293 DOI: 10.1016/j.bpj.2023.08.009 |
0.35 |
|
| 2023 |
Oshinowo O, Azer SS, Lin J, Lam WA. Why Platelet Mechanotransduction Matters for Hemostasis and Thrombosis. Journal of Thrombosis and Haemostasis : Jth. PMID 37331517 DOI: 10.1016/j.jtha.2023.06.010 |
0.336 |
|
| 2023 |
Cheng X, Caruso C, Lam WA, Graham MD. Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders. Biorxiv : the Preprint Server For Biology. PMID 37293094 DOI: 10.1101/2023.05.16.541016 |
0.322 |
|
| 2022 |
Caruso C, Fay ME, Cheng X, Liu AY, Park SI, Sulchek TA, Graham MD, Lam WA. Pathologic mechanobiological interactions between red blood cells and endothelial cells directly induce vasculopathy in iron deficiency anemia. Iscience. 25: 104606. PMID 35800766 DOI: 10.1016/j.isci.2022.104606 |
0.307 |
|
| 2022 |
Sun Y, Oshinowo O, Myers DR, Lam WA, Alexeev A. Resolving the missing link between single platelet force and clot contractile force. Iscience. 25: 103690. PMID 35059605 DOI: 10.1016/j.isci.2021.103690 |
0.315 |
|
| 2021 |
Lin J, Sorrells MG, Lam WA, Neeves KB. Physical forces regulating hemostasis and thrombosis: Vessels, cells, and molecules in illustrated review. Research and Practice in Thrombosis and Haemostasis. 5: e12548. PMID 34278188 DOI: 10.1002/rth2.12548 |
0.362 |
|
| 2021 |
Tutwiler V, Litvinov RI, Protopopova A, Nagaswami C, Villa C, Woods E, Abdulmalik O, Siegel DL, Russell JE, Muzykantov VR, Lam WA, Myers DR, Weisel JW. Pathologically stiff erythrocytes impede contraction of blood clots. Journal of Thrombosis and Haemostasis : Jth. PMID 34233380 DOI: 10.1111/jth.15407 |
0.323 |
|
| 2021 |
Sun Y, Myers DR, Nikolov SV, Oshinowo O, Baek J, Bowie SM, Lambert TP, Woods E, Sakurai Y, Lam WA, Alexeev A. Platelet heterogeneity enhances blood clot volumetric contraction: An example of asynchrono-mechanical amplification. Biomaterials. 274: 120828. PMID 33964792 DOI: 10.1016/j.biomaterials.2021.120828 |
0.37 |
|
| 2020 |
Zhang X, Caruso C, Lam WA, Graham MD. Flow-induced segregation and dynamics of red blood cells in sickle cell disease. Physical Review Fluids. 5. PMID 34095646 DOI: 10.1103/physrevfluids.5.053101 |
0.352 |
|
| 2020 |
Sathialingam E, Williams EK, Lee SY, McCracken CE, Lam WA, Buckley EM. Hematocrit significantly confounds diffuse correlation spectroscopy measurements of blood flow. Biomedical Optics Express. 11: 4786-4799. PMID 32923078 DOI: 10.1364/Boe.397613 |
0.311 |
|
| 2020 |
Islam M, Raj A, McFarland B, Brink HM, Ciciliano J, Fay M, Myers DR, Flowers C, Waller EK, Lam W, Alexeev A, Sulchek T. Stiffness based enrichment of leukemia cells using microfluidics. Apl Bioengineering. 4: 036101. PMID 32637856 DOI: 10.1063/1.5143436 |
0.355 |
|
| 2020 |
Ojaghi A, Carrazana G, Caruso C, Abbas A, Myers DR, Lam WA, Robles FE. Label-free hematology analysis using deep-ultraviolet microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32561645 DOI: 10.1073/Pnas.2001404117 |
0.415 |
|
| 2020 |
Qiu Y, Lam WA. Platelet-rich plasma as endothelial rocket fuel for engineered in vitro microvasculature. Journal of Thrombosis and Haemostasis : Jth. PMID 32346985 DOI: 10.1111/Jth.14823 |
0.314 |
|
| 2020 |
Mangin PH, Gardiner EE, Nesbitt WS, Kerrigan SW, Korin N, Lam WA, Panteleev MA. In vitro flow based systems to study platelet function and thrombus formation: Recommendations for standardization: Communication from the SSC on Biorheology of the ISTH. Journal of Thrombosis and Haemostasis : Jth. 18: 748-752. PMID 32112535 DOI: 10.1111/Jth.14717 |
0.391 |
|
| 2020 |
Oshinowo O, Lambert T, Sakurai Y, Copeland R, Hansen CE, Lam WA, Myers DR. Getting a good view: imaging of platelets under flow. Platelets. 1-10. PMID 32106734 DOI: 10.1080/09537104.2020.1732320 |
0.429 |
|
| 2020 |
Hu L, Ni F, Wang X, Fay ME, Young KM, Lam WA, Sulchek TA, Qu CK. Decreased cell stiffness enhances leukemia development and progression. Leukemia. PMID 32094464 DOI: 10.1038/S41375-020-0763-7 |
0.419 |
|
| 2020 |
Jenny L, Melmer A, Laimer M, Hardy ET, Lam WA, Schroeder V. Diabetes affects endothelial cell function and alters fibrin clot formation in a microvascular flow model: A pilot study. Diabetes & Vascular Disease Research. 17: 1479164120903044. PMID 32037878 DOI: 10.1177/1479164120903044 |
0.33 |
|
| 2020 |
Zhang X, Caruso C, Lam WA, Graham MD. Flow-induced segregation and dynamics of red blood cells in sickle cell disease Physical Review Fluids. 5. DOI: 10.1103/Physrevfluids.5.053101 |
0.454 |
|
| 2019 |
Qiu Y, Myers DR, Lam WA. The biophysics and mechanics of blood from a materials perspective. Nature Reviews. Materials. 4: 294-311. PMID 32435512 DOI: 10.1038/S41578-019-0099-Y |
0.461 |
|
| 2019 |
Hesh CA, Qiu Y, Lam WA. Vascularized Microfluidics and the Blood-Endothelium Interface. Micromachines. 11. PMID 31878018 DOI: 10.3390/Mi11010018 |
0.356 |
|
| 2019 |
Lee SY, Cowdrick KR, Sanders B, Sathialingam E, McCracken CE, Lam WA, Joiner CH, Buckley EM. Noninvasive optical assessment of resting-state cerebral blood flow in children with sickle cell disease. Neurophotonics. 6: 035006. PMID 31482101 DOI: 10.1117/1.Nph.6.3.035006 |
0.349 |
|
| 2019 |
Williams EK, García JR, Mannino RG, Schneider RS, Lam WA, García AJ. Enabling mesenchymal stromal cell immunomodulatory analysis using scalable platforms. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 31135880 DOI: 10.1093/Intbio/Zyz014 |
0.316 |
|
| 2019 |
Ni F, Yu WM, Wang X, Fay ME, Young KM, Qiu Y, Lam WA, Sulchek TA, Cheng T, Scadden DT, Qu CK. Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell Stem Cell. PMID 30880025 DOI: 10.1016/J.Stem.2019.02.009 |
0.368 |
|
| 2019 |
Oshinowo OT, Copeland R, Caruso C, Fay ME, Leong T, Bennett CM, Lam WA, Myers DR. Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia Blood. 134: 1096-1096. DOI: 10.1182/Blood-2019-129573 |
0.426 |
|
| 2019 |
Qiu Y, Sakurai Y, Lam WA. Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay Blood. 134: 441-441. DOI: 10.1182/Blood-2019-128718 |
0.433 |
|
| 2019 |
Caruso C, Zhang X, Sakurai Y, Li W, Fay ME, Carden MA, Myers DR, Mannino RG, Joiner CH, Graham MD, Lam WA. Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease Blood. 134: 3560-3560. DOI: 10.1182/Blood-2019-125408 |
0.477 |
|
| 2018 |
Williams EK, Oshinowo O, Ravindran A, Lam WA, Myers DR. Feeling the Force: Measurements of Platelet Contraction and Their Diagnostic Implications. Seminars in Thrombosis and Hemostasis. PMID 30566972 DOI: 10.1055/S-0038-1676315 |
0.457 |
|
| 2018 |
Qiu Y, Ahn B, Sakurai Y, Hansen C, Tran R, Mimche PN, Mannino R, Ciciliano JC, Lamb TJ, Joiner CH, Ofori-Acquah SF, Lam WA. Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease. Nature Biomedical Engineering. 2: 453-463. PMID 30533277 DOI: 10.1038/S41551-018-0224-Z |
0.339 |
|
| 2018 |
Guruprasad P, Mannino RG, Caruso C, Zhang H, Josephson CD, Roback JD, Lam WA. Integrated Automated Particle Tracking Microfluidic Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders. American Journal of Hematology. PMID 30417938 DOI: 10.1002/Ajh.25345 |
0.448 |
|
| 2018 |
Mannino RG, Pradhan P, Roy K, Lam WA. 3D in vitro microvascular model-based lymphoma model. Methods in Cell Biology. 146: 149-158. PMID 30037459 DOI: 10.1016/Bs.Mcb.2018.05.007 |
0.308 |
|
| 2018 |
Hansen CE, Qiu Y, McCarty OJT, Lam WA. Platelet Mechanotransduction. Annual Review of Biomedical Engineering. 20: 253-275. PMID 29865873 DOI: 10.1146/annurev-bioeng-062117-121215 |
0.306 |
|
| 2018 |
Mannino RG, Qiu Y, Lam WA. Endothelial cell culture in microfluidic devices for investigating microvascular processes. Biomicrofluidics. 12: 042203. PMID 29861814 DOI: 10.1063/1.5024901 |
0.35 |
|
| 2018 |
Mannino RG, Pandian NK, Jain A, Lam WA. Engineering "Endothelialized" Microfluidics for Investigating Vascular and Hematologic Processes Using Non-Traditional Fabrication Techniques. Current Opinion in Biomedical Engineering. 5: 13-20. PMID 29756078 DOI: 10.1016/J.Cobme.2017.11.006 |
0.354 |
|
| 2018 |
Islam M, Mezencev R, McFarland B, Brink H, Campbell B, Tasadduq B, Waller EK, Lam W, Alexeev A, Sulchek T. Microfluidic cell sorting by stiffness to examine heterogenic responses of cancer cells to chemotherapy. Cell Death & Disease. 9: 239. PMID 29445159 DOI: 10.1038/S41419-018-0266-X |
0.324 |
|
| 2018 |
Sakurai Y, Hardy ET, Ahn B, Tran R, Fay ME, Ciciliano JC, Mannino RG, Myers DR, Qiu Y, Carden MA, Baldwin WH, Meeks SL, Gilbert GE, Jobe SM, Lam WA. A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nature Communications. 9: 509. PMID 29410404 DOI: 10.1038/S41467-018-02990-X |
0.432 |
|
| 2018 |
Jenny L, Dobó J, Gál P, Pál G, Lam WA, Schroeder V. MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model. Plos One. 13: e0191292. PMID 29324883 DOI: 10.1371/Journal.Pone.0191292 |
0.36 |
|
| 2018 |
Woodall JLA, Fay ME, Ciciliano J, Abbaspour R, Bakir MS, Lam WA. Real-Time Visualization of Shear-Dependent Erythrocyte Deformation into Schistocytes Using Single Micron Microfluidics Blood. 132: 1030-1030. DOI: 10.1182/Blood-2018-99-120113 |
0.373 |
|
| 2018 |
Caruso C, Guruprasad P, Mannino RG, Zhang H, Josephson CD, Roback JD, Lam WA. Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders Blood. 132: 1033-1033. DOI: 10.1182/Blood-2018-99-118830 |
0.434 |
|
| 2018 |
Kholmukhamedov A, Sakurai Y, Hardy EL, Lam WA, Jobe SM. Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability Blood. 132: 2421-2421. DOI: 10.1182/Blood-2018-99-117004 |
0.399 |
|
| 2018 |
Oshinowo OT, Copeland R, Bennett CM, Lam WA, Myers DR. Platelet Contraction Force As a Biophysical Biomarker for Bleeding Risk in Patients with Immune Thrombocytopenia Blood. 132: 517-517. DOI: 10.1182/Blood-2018-99-115292 |
0.434 |
|
| 2018 |
Copeland R, Oshinowo OT, Sakurai Y, Fay ME, Petrich BG, Brainard B, Lam WA, Myers DR. A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species Blood. 132: 869-869. DOI: 10.1182/Blood-2018-99-113107 |
0.428 |
|
| 2018 |
Pandian NK, Mannino RG, Lam WA, Jain A. Thrombosis-on-a-chip: Prospective impact of microphysiological models of vascular thrombosis Current Opinion in Biomedical Engineering. 5: 29-34. DOI: 10.1016/J.Cobme.2017.12.001 |
0.374 |
|
| 2017 |
Zhang Y, Qiu Y, Blanchard AT, Chang Y, Brockman JM, Ma VP, Lam WA, Salaita K. Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29269394 DOI: 10.1073/Pnas.1710828115 |
0.417 |
|
| 2017 |
Brockman JM, Blanchard AT, Pui-Yan V, Derricotte WD, Zhang Y, Fay ME, Lam WA, Evangelista FA, Mattheyses AL, Salaita K. Mapping the 3D orientation of piconewton integrin traction forces. Nature Methods. PMID 29256495 DOI: 10.1038/Nmeth.4536 |
0.329 |
|
| 2017 |
Tasadduq B, Lam W, Alexeev A, Sarioglu AF, Sulchek T. Enhancing size based size separation through vertical focus microfluidics using secondary flow in a ridged microchannel. Scientific Reports. 7: 17375. PMID 29234006 DOI: 10.1038/S41598-017-17388-W |
0.302 |
|
| 2017 |
Ciciliano JC, Abbaspour R, Woodall J, Wu C, Bakir MS, Lam WA. Probing blood cell mechanics of hematologic processes at the single micron level. Lab On a Chip. PMID 29052682 DOI: 10.1039/C7Lc00720E |
0.479 |
|
| 2017 |
Carden MA, Fay ME, Lu X, Mannino RG, Sakurai Y, Ciciliano JC, Hansen CE, Chonat S, Joiner CH, Wood DK, Lam WA. Impact of extracellular fluid tonicity on sickle red blood cell deformability and adhesion. Blood. PMID 28978568 DOI: 10.1182/Blood-2017-04-780635 |
0.403 |
|
| 2017 |
Hansen CE, Lam WA. Clinical Implications of Single-Cell Microfluidic Devices for Hematological Disorders. Analytical Chemistry. PMID 28942646 DOI: 10.1021/Acs.Analchem.7B01013 |
0.332 |
|
| 2017 |
Buckley EM, Platt MO, Lam WA. Novel in vivo and in vitro techniques to image and model the cerebral vasculature in sickle cell disease. Blood Cells, Molecules & Diseases. PMID 28822622 DOI: 10.1016/J.Bcmd.2017.08.008 |
0.322 |
|
| 2017 |
Tran R, Myers DR, Denning G, Shields JE, Lytle AM, Alrowais H, Qiu Y, Sakurai Y, Li WC, Brand O, Le Doux JM, Spencer HT, Doering CB, Lam WA. Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28780274 DOI: 10.1016/J.Ymthe.2017.07.002 |
0.33 |
|
| 2017 |
Qiu Y, Tong S, Zhang L, Sakurai Y, Myers DR, Hong L, Lam WA, Bao G. Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions. Nature Communications. 8: 15594. PMID 28593939 DOI: 10.1038/Ncomms15594 |
0.306 |
|
| 2017 |
Hansen CE, Myers DR, Baldwin WH, Sakurai Y, Meeks SL, Lyon LA, Lam WA. Platelet-Microcapsule Hybrids Leverage Contractile Force for Targeted Delivery of Hemostatic Agents. Acs Nano. PMID 28541681 DOI: 10.1021/Acsnano.7B00929 |
0.397 |
|
| 2017 |
Islam M, Brink H, Blanche S, DiPrete C, Bongiorno T, Stone N, Liu A, Philip A, Wang G, Lam W, Alexeev A, Waller EK, Sulchek T. Microfluidic Sorting of Cells by Viability Based on Differences in Cell Stiffness. Scientific Reports. 7: 1997. PMID 28515450 DOI: 10.1038/S41598-017-01807-Z |
0.458 |
|
| 2017 |
Carden MA, Fay M, Sakurai Y, McFarland B, Blanche S, Diprete C, Joiner CH, Sulchek T, Lam WA. Normal Saline is Associated with Increased Sickle Red Cell Stiffness and Prolonged Transit Times in a Microfluidic Model of the Capillary System. Microcirculation (New York, N.Y. : 1994). PMID 28106307 DOI: 10.1111/Micc.12353 |
0.408 |
|
| 2017 |
Mannino RG, Santiago-Miranda AN, Pradhan P, Qiu Y, Mejias JC, Neelapu SS, Roy K, Lam WA. 3D microvascular model recapitulates the diffuse large B-cell lymphoma tumor microenvironment in vitro. Lab On a Chip. PMID 28054086 DOI: 10.1039/C6Lc01204C |
0.313 |
|
| 2016 |
Myers DR, Qiu Y, Fay ME, Tennenbaum M, Chester D, Cuadrado J, Sakurai Y, Baek J, Tran R, Ciciliano JC, Ahn B, Mannino RG, Bunting ST, Bennett C, Briones M, ... ... Lam WA, et al. Single-platelet nanomechanics measured by high-throughput cytometry. Nature Materials. PMID 27723740 DOI: 10.1038/Nmat4772 |
0.451 |
|
| 2016 |
Fay ME, Myers DR, Kumar A, Turbyfield CT, Byler R, Crawford K, Mannino RG, Laohapant A, Tyburski EA, Sakurai Y, Rosenbluth MJ, Switz NA, Sulchek TA, Graham MD, Lam WA. Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858400 DOI: 10.1073/Pnas.1508920113 |
0.77 |
|
| 2016 |
Hansen CE, Myers DR, Sakurai Y, Baldwin WH, Meeks SL, Lyon LA, Lam WA. Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors Blood. 128: 81-81. DOI: 10.1182/Blood.V128.22.81.81 |
0.384 |
|
| 2016 |
Ciciliano J, Abbaspour R, Wu C, Bakir M, Lam WA. A Microengineered Matrix to Decouple the Biophysical and Biochemical Mechanisms of Blood Cell Interactions with Thrombi and Vascular Wall Matrices Blood. 128: 555-555. DOI: 10.1182/Blood.V128.22.555.555 |
0.486 |
|
| 2015 |
Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JC, Ni H, Ariëns RA, Wolberg AS. Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking. Blood. PMID 26324704 DOI: 10.1182/Blood-2015-06-652263 |
0.357 |
|
| 2015 |
Mannino RG, Myers DR, Ahn B, Wang Y, Margo Rollins, Gole H, Lin AS, Guldberg RE, Giddens DP, Timmins LH, Lam WA. "Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions". Scientific Reports. 5: 12401. PMID 26202603 DOI: 10.1038/Srep12401 |
0.458 |
|
| 2015 |
Rappaport KM, McCracken CC, Beniflah J, Little WK, Fletcher DA, Lam WA, Shane AL. Assessment of a Smartphone Otoscope Device for the Diagnosis and Management of Otitis Media. Clinical Pediatrics. PMID 26156976 DOI: 10.1177/0009922815593909 |
0.454 |
|
| 2015 |
Qiu Y, Ciciliano J, Myers DR, Tran R, Lam WA. Platelets and physics: How platelets "feel" and respond to their mechanical microenvironment. Blood Reviews. PMID 26005062 DOI: 10.1016/J.Blre.2015.05.002 |
0.428 |
|
| 2015 |
Sakurai Y, Fitch-Tewfik JL, Qiu Y, Ahn B, Myers DR, Tran R, Fay ME, Ding L, Spearman PW, Michelson AD, Flaumenhaft R, Lam WA. Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition. Blood. 126: 531-8. PMID 25964667 DOI: 10.1182/Blood-2014-11-607614 |
0.377 |
|
| 2015 |
Ciciliano JC, Sakurai Y, Myers DR, Fay ME, Hechler B, Meeks S, Li R, Dixon JB, Lyon LA, Gachet C, Lam WA. Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. Blood. PMID 25931587 DOI: 10.1182/Blood-2015-02-628594 |
0.407 |
|
| 2015 |
Kee MF, Myers DR, Sakurai Y, Lam WA, Qiu Y. Platelet mechanosensing of collagen matrices. Plos One. 10: e0126624. PMID 25915413 DOI: 10.1182/Blood.V124.21.1437.1437 |
0.421 |
|
| 2015 |
Wang G, Crawford K, Turbyfield C, Lam W, Alexeev A, Sulchek T. Microfluidic cellular enrichment and separation through differences in viscoelastic deformation. Lab On a Chip. 15: 532-40. PMID 25411722 DOI: 10.1039/C4Lc01150C |
0.458 |
|
| 2015 |
Wang Y, Mannino RG, Myers DR, Li W, Joiner CH, Lam WA. Vessel Geometry Interacts with Red Blood Cell Stiffness to Promote Endothelial Dysfunction in Sickle Cell Disease Blood. 126: 965-965. DOI: 10.1182/Blood.V126.23.965.965 |
0.439 |
|
| 2015 |
Tran R, Myers DR, Shields JE, Ahn B, Qiu Y, Hansen C, Sakurai Y, Moot R, Spencer HT, Doering CB, Lam WA. Improving Lentiviral Transduction Efficiency with Microfluidic Systems Blood. 126: 4415-4415. DOI: 10.1182/Blood.V126.23.4415.4415 |
0.396 |
|
| 2015 |
Sakurai Y, Hardy ET, Ahn B, Meeks SL, Baldwin WH, Jobe SM, Lam WA. Engineering a Valve-Regulated Endothelialized Microfluidic Device As an "in Vitro" Bleeding Time for Assessing Global Hemostasis Blood. 126: 3485-3485. DOI: 10.1182/Blood.V126.23.3485.3485 |
0.416 |
|
| 2015 |
Rollins MR, Ahn B, Sakurai Y, Lam WA. Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device Blood. 126: 3381-3381. DOI: 10.1182/Blood.V126.23.3381.3381 |
0.501 |
|
| 2015 |
Qiu Y, Ahn B, Sakurai Y, Hansen C, Joiner CH, Ofori-Acquah SF, Lam WA. Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease Blood. 126: 240-240. DOI: 10.1182/Blood.V126.23.240.240 |
0.412 |
|
| 2015 |
Carden MA, Fay ME, Sakurai Y, Mannino RG, Ciciliano J, Tran R, Lam WA. Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time Blood. 126: 2164-2164. DOI: 10.1182/Blood.V126.23.2164.2164 |
0.379 |
|
| 2015 |
Strauss H, Myers DR, Rollins MR, Weisel JW, Lam WA. Clot Contraction-Mediated Erythrocyte Packing Is Significantly Altered in Sickle Cell Disease Blood. 126: 215-215. DOI: 10.1182/Blood.V126.23.215.215 |
0.457 |
|
| 2015 |
Wang G, Crawford K, Turbyfield C, Lam W, Alexeev A, Sulchek T. Microfluidic cellular enrichment and separation through differences in viscoelastic deformation Lab On a Chip - Miniaturisation For Chemistry and Biology. 15: 532-540. DOI: 10.1039/c4lc01150c |
0.353 |
|
| 2014 |
Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 14430-5. PMID 25246564 DOI: 10.1073/Pnas.1322917111 |
0.411 |
|
| 2014 |
Brown AC, Stabenfeldt SE, Ahn B, Hannan RT, Dhada KS, Herman ES, Stefanelli V, Guzzetta N, Alexeev A, Lam WA, Lyon LA, Barker TH. Ultrasoft microgels displaying emergent platelet-like behaviours. Nature Materials. 13: 1108-14. PMID 25194701 DOI: 10.1038/Nmat4066 |
0.387 |
|
| 2014 |
Chinnadurai R, Garcia MA, Sakurai Y, Lam WA, Kirk AD, Galipeau J, Copland IB. Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo. Stem Cell Reports. 3: 60-72. PMID 25068122 DOI: 10.1016/J.Stemcr.2014.05.003 |
0.347 |
|
| 2014 |
Ahn B, Wang Z, Archer DR, Lam WA. Using microfluidics to investigate hematopoietic stem cell and microniche interactions at the single cell level. Methods in Molecular Biology (Clifton, N.J.). 1185: 223-33. PMID 25062632 DOI: 10.1007/978-1-4939-1133-2_15 |
0.301 |
|
| 2014 |
Ciciliano JC, Tran R, Sakurai Y, Lam WA. The platelet and the biophysical microenvironment: lessons from cellular mechanics. Thrombosis Research. 133: 532-7. PMID 24440140 DOI: 10.1016/J.Thromres.2013.12.037 |
0.472 |
|
| 2014 |
McGann PT, Tyburski E, de Oliveira V, Santos B, Ware RE, Lam WA. An Accurate and Rapid Color-Based Point-of-Care Assay for the Detection of Severe Anemia in Low Resource Settings Blood. 124: 688-688. DOI: 10.1182/Blood.V124.21.688.688 |
0.313 |
|
| 2014 |
Mannino R, Myers DR, Ahn B, Gole H, Wang Y, Lin A, Guldberg R, Giddens D, Timmins L, Lam WA. Vascular Geometry and Flow Profile Mediate Pathological Cell-Cell Interactions in Sickle Cell Disease As Measured with "Do-It-Yourself" "Endothelial-Ized" Microfluidics Blood. 124: 454-454. DOI: 10.1182/Blood.V124.21.454.454 |
0.442 |
|
| 2014 |
Rollins MR, Ahn B, Sakurai Y, Ciciliano JC, Lam WA. Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System Blood. 124: 4155-4155. DOI: 10.1182/Blood.V124.21.4155.4155 |
0.494 |
|
| 2014 |
Sakurai Y, Fitch-Tewfik JL, Qiu Y, Myers DR, Ahn B, Flaumenhaft R, Lam WA. “Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates. Blood. 124: 2764-2764. DOI: 10.1182/Blood.V124.21.2764.2764 |
0.406 |
|
| 2014 |
Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino R, Tran R, Ahn B, Hardy E, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness Blood. 124: 1438-1438. DOI: 10.1182/Blood.V124.21.1438.1438 |
0.427 |
|
| 2013 |
Liu F, Gamez G, Myers DR, Clemmons W, Lam WA, Jobe SM. Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth. The Journal of Biological Chemistry. 288: 30672-81. PMID 24014035 DOI: 10.1074/Jbc.M113.472688 |
0.389 |
|
| 2013 |
Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A, Blanchard E, Chang B, Myers DR, Ju L, Tran R, Reece D, Christensen H, Boukour S, Debili N, Strom TS, ... ... Lam WA, et al. Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling. Blood. 122: 1695-706. PMID 23881916 DOI: 10.1182/Blood-2013-03-484550 |
0.311 |
|
| 2013 |
Tran R, Myers DR, Ciciliano J, Trybus Hardy EL, Sakurai Y, Ahn B, Qiu Y, Mannino RG, Fay ME, Lam WA. Biomechanics of haemostasis and thrombosis in health and disease: from the macro- to molecular scale. Journal of Cellular and Molecular Medicine. 17: 579-96. PMID 23490277 DOI: 10.1111/Jcmm.12041 |
0.456 |
|
| 2013 |
Fay ME, Myers DR, Kumar A, Byler R, Sulchek TA, Graham MD, Lam WA. White Blood Cell Mechanics Mediate Glucocorticoid- and Catecholamine-Induced Demargination Blood. 122: 3459-3459. DOI: 10.1182/Blood.V122.21.3459.3459 |
0.385 |
|
| 2013 |
Ciciliano JC, Myers DR, Fay ME, Sakurai Y, Li R, Lyon A, Lam WA. New Insights Into The Mechanisms Of Ferric Chloride-Induced Thrombosis: a Reductionist Microfluidic Approach Blood. 122: 2308-2308. DOI: 10.1182/Blood.V122.21.2308.2308 |
0.478 |
|
| 2012 |
Myers DR, Sakurai Y, Tran R, Ahn B, Hardy ET, Mannino R, Kita A, Tsai M, Lam WA. Endothelialized microfluidics for studying microvascular interactions in hematologic diseases. Journal of Visualized Experiments : Jove. PMID 22760254 DOI: 10.3791/3958 |
0.471 |
|
| 2012 |
Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA. In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. The Journal of Clinical Investigation. 122: 408-18. PMID 22156199 DOI: 10.1172/Jci58753 |
0.614 |
|
| 2012 |
Mannino R, Myers DR, Sakurai Y, Ware RE, Barabino G, Lam W. Increased Erythrocyte Rigidity Is Sufficient to Cause Endothelial Dysfunction in Sickle Cell Disease Blood. 120: 818-818. DOI: 10.1182/Blood.V120.21.818.818 |
0.464 |
|
| 2012 |
Qiu Y, Brown AC, Jung WJ, Sakurai Y, Mannino R, Myers DR, Tran R, Bao G, Barker TH, Lam W. Platelet Mechanosensing: Adhesion and Spreading On Immobilized Fibrinogen Depends On Substrate Stiffness Blood. 120: 384-384. DOI: 10.1182/Blood.V120.21.384.384 |
0.42 |
|
| 2012 |
Hardy E, Sakurai Y, Sanjaya N, Wolberg AS, Lam W. Effect of Locally Applied Electricity On Clot Formation and Hemostasis. Blood. 120: 2220-2220. DOI: 10.1182/Blood.V120.21.2220.2220 |
0.371 |
|
| 2012 |
Myers DR, Brown AC, Qiu Y, Sakurai Y, Tran R, Ahn B, Mannino R, Sulchek T, Lyon A, Barker TH, Lam W. High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels. Blood. 120: 2172-2172. DOI: 10.1182/Blood.V120.21.2172.2172 |
0.439 |
|
| 2012 |
Sakurai Y, Qiu Y, Ahn B, Lam W. Platelet α-Granule Secretion and Cytoskeletal Rearrangements Are Spatially Regulated At the Micro/Nanoscale. Blood. 120: 2163-2163. DOI: 10.1182/Blood.V120.21.2163.2163 |
0.399 |
|
| 2012 |
Ahn B, Sakurai Y, Myers DR, Qiu Y, Hardy E, Tran R, Mannino R, Wolberg AS, Lam W. An “Endothelialized” Microfluidic System That Distinguishes Procoagulant Mechanisms in Arterial and Venous Thrombosis Blood. 120: 1071-1071. DOI: 10.1182/Blood.V120.21.1071.1071 |
0.403 |
|
| 2012 |
Myers DR, Fletcher DA, Lam WA. Towards High-Throughput Cell Mechanics Assays for Research and Clinical Applications Nano and Cell Mechanics: Fundamentals and Frontiers. 255-292. DOI: 10.1002/9781118482568.ch10 |
0.513 |
|
| 2011 |
Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA. Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. Plos One. 6: e26437. PMID 22028878 DOI: 10.1371/Journal.Pone.0026437 |
0.598 |
|
| 2011 |
Lam WA, Chaudhuri O, Crow A, Webster KD, Li TD, Kita A, Huang J, Fletcher DA. Mechanics and contraction dynamics of single platelets and implications for clot stiffening. Nature Materials. 10: 61-6. PMID 21131961 DOI: 10.1038/Nmat2903 |
0.726 |
|
| 2011 |
Myers DR, Sakurai Y, Chappa P, Barabino G, Archer DR, Lam W. Measuring the Direct Effects of Sickle Cell Vaso-Occlusion on Endothelial Cells Using Microfluidic Technology Blood. 118: 897-897. DOI: 10.1182/Blood.V118.21.897.897 |
0.5 |
|
| 2011 |
Sakurai Y, Myers DR, Kita A, Lam W. A Novel Assay That Integrates the Effects of Multiple Agonists At the Single-Platelet Level, Blood. 118: 3258-3258. DOI: 10.1182/Blood.V118.21.3258.3258 |
0.411 |
|
| 2011 |
Liu F, Gamez G, Myers DR, Lam W, Jobe SM. Mitochondrially-Mediated Platelet Integrin AlphaIIbbeta3 Inactivation Limits Platelet Recruitment and Thrombus Growth, Blood. 118: 3251-3251. DOI: 10.1182/Blood.V118.21.3251.3251 |
0.383 |
|
| 2011 |
Myers DR, Sulchek T, Lam W. Nanomechanics of Platelet Contractility Blood. 118: 2202-2202. DOI: 10.1182/Blood.V118.21.2202.2202 |
0.469 |
|
| 2011 |
Kita A, Sakurai Y, Myers DR, Rounsevell R, Seok TJ, Yu K, Huang J, Wu M, Fletcher D, Lam W. Platelet Sensing of Microenviornmental Geometry Guides Adhesion and Spreading: A Quantitative Study At the Single-Cell Level Blood. 118: 2192-2192. DOI: 10.1182/Blood.V118.21.2192.2192 |
0.597 |
|
| 2010 |
Lam WA, Cao L, Umesh V, Keung AJ, Sen S, Kumar S. Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression. Molecular Cancer. 9: 35. PMID 20144241 DOI: 10.1186/1476-4598-9-35 |
0.304 |
|
| 2009 |
Breslauer DN, Maamari RN, Switz NA, Lam WA, Fletcher DA. Mobile phone based clinical microscopy for global health applications. Plos One. 4: e6320. PMID 19623251 DOI: 10.1371/Journal.Pone.0006320 |
0.527 |
|
| 2009 |
Chaudhuri O, Parekh SH, Lam WA, Fletcher DA. Combined atomic force microscopy and side-view optical imaging for mechanical studies of cells. Nature Methods. 6: 383-7. PMID 19363493 DOI: 10.1038/Nmeth.1320 |
0.793 |
|
| 2008 |
Hsiao SC, Crow AK, Lam WA, Bertozzi CR, Fletcher DA, Francis MB. DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells. Angewandte Chemie (International Ed. in English). 47: 8473-7. PMID 18798192 DOI: 10.1002/Anie.200802525 |
0.769 |
|
| 2008 |
Rosenbluth MJ, Lam WA, Fletcher DA. Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry. Lab On a Chip. 8: 1062-70. PMID 18584080 DOI: 10.1039/B802931H |
0.798 |
|
| 2008 |
Lam WA, Rosenbluth MJ, Fletcher DA. Increased leukaemia cell stiffness is associated with symptoms of leucostasis in paediatric acute lymphoblastic leukaemia. British Journal of Haematology. 142: 497-501. PMID 18544083 DOI: 10.1111/J.1365-2141.2008.07219.X |
0.763 |
|
| 2008 |
Tsai M, Hunt TP, Fletcher DA, Lam WA. Three-Dimensional Endothelium-Lined Microfabricated Channels as in Vitro assays for Sickle Cell Vaso-Occlusion Blood. 112: 4790-4790. DOI: 10.1182/Blood.V112.11.4790.4790 |
0.669 |
|
| 2008 |
Lam WA, Hansen WR, Huang J, Mentzer W, Lubin BH, Kuypers FA, Fletcher DA. Aldosterone Promotes Inflammation and Endothelial Cell-Sickle Cell Adhesion: Potential for a New Therapeutic Target in Sickle Cell Disease Blood. 112: 125-125. DOI: 10.1182/Blood.V112.11.125.125 |
0.772 |
|
| 2008 |
Breslauer DN, Maamari RN, Lam W, Hunt T, Lee LP, Fletcher DA. Cellscope: Mobile microscopy for single cell analysis 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 456-458. |
0.524 |
|
| 2007 |
Lam WA, Rosenbluth MJ, Fletcher DA. Chemotherapy exposure increases leukemia cell stiffness. Blood. 109: 3505-8. PMID 17179225 DOI: 10.1182/Blood-2006-08-043570 |
0.809 |
|
| 2006 |
Rosenbluth MJ, Lam WA, Fletcher DA. Force microscopy of nonadherent cells: a comparison of leukemia cell deformability. Biophysical Journal. 90: 2994-3003. PMID 16443660 DOI: 10.1529/Biophysj.105.067496 |
0.806 |
|
| 2006 |
Lam WA, Rosenbluth MJ, Fletcher DA. Chemotherapy Exposure Decreases Leukemia Cell Deformability as Determined by Atomic Force Microscopy: Implications for Leukostasis in Acute Leukemia. Blood. 108: 2359-2359. DOI: 10.1182/Blood.V108.11.2359.2359 |
0.796 |
|
| 2006 |
Stachowiak JC, Li TH, Rasooly J, Lam WA, Fletcher DA. Development of a piezoelectric microjet injector for transdermal drug delivery Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 308-310. |
0.611 |
|
| 2004 |
Rosenbluth MJ, Lam WA, Fletcher DA. Contribution of cell mechanics to acute leukemia Advances in Bioengineering, Bed. 395-396. |
0.777 |
|
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