Nadja B. Cech, Ph.D. - Publications

Affiliations: 
2001- Chemistry  University of North Carolina at Greensboro, Greensboro, NC, United States 
Area:
Mass spectrometry, botany
Website:
https://www.uncg.edu/che/faculty/cech/team.html

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vidar WS, Baumeister TUH, Caesar LK, Kellogg JJ, Todd DA, Linington RG, M Kvalheim O, Cech NB. Interaction Metabolomics to Discover Synergists in Natural Product Mixtures. Journal of Natural Products. PMID 37052585 DOI: 10.1021/acs.jnatprod.2c00518  0.758
2023 Khadilkar A, Bunch ZL, Wagoner J, Ravindran V, Oda JM, Vidar WS, Clark TN, Manwill PK, Todd DA, Barr SA, Olinger LK, Fink SL, Strangman WK, Linington RG, MacMillan JB, ... Cech NB, et al. Modulation of SARS-CoV-2 Infection by and Its Alkaloid Constituents. Journal of Natural Products. PMID 37043739 DOI: 10.1021/acs.jnatprod.3c00159  0.632
2021 Pelzer CV, Houriet J, Crandall WJ, Todd DA, Cech NB, Jones DD. More Than Just a Weed: An Exploration of the Antimicrobial Activity of Rumex crispus using a Multivariate Data Analysis Approach. Planta Medica. PMID 34695862 DOI: 10.1055/a-1652-1547  0.383
2021 Clark TN, Houriet J, Vidar WS, Kellogg JJ, Todd DA, Cech NB, Linington RG. Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability. Journal of Natural Products. PMID 33666420 DOI: 10.1021/acs.jnatprod.0c01376  0.728
2021 Khin M, Knowles SL, Crandall WJ, Jones DD, Oberlies NH, Cech NB, Houriet J. Capturing the antimicrobial profile of Rosmarinus officinalis against methicillin-resistant Staphylococcus aureus (MRSA) with bioassay-guided fractionation and bioinformatics. Journal of Pharmaceutical and Biomedical Analysis. 197: 113965. PMID 33640687 DOI: 10.1016/j.jpba.2021.113965  0.375
2020 Nguyen JT, Tian DD, Tanna RS, Hadi DL, Bansal S, Calamia JC, Arian CM, Shireman LM, Molnár B, Horváth M, Kellogg JJ, Layton ME, White JR, Cech NB, Boyce RD, et al. Assessing Transporter-Mediated Natural Product-Drug Interactions via In vitro-In vivo Extrapolation: Clinical Evaluation with a Probe Cocktail. Clinical Pharmacology and Therapeutics. PMID 33174626 DOI: 10.1002/cpt.2107  0.609
2020 Brown AR, Ettefagh KA, Todd DA, Cole PS, Egan JM, Foil DH, Lacey EP, Cech NB. Bacterial efflux inhibitors are widely distributed in land plants. Journal of Ethnopharmacology. 113533. PMID 33137433 DOI: 10.1016/j.jep.2020.113533  0.786
2020 Jones DD, Caesar LK, Pelzer CV, Crandall WJ, Jenul C, Todd DA, Horswill AR, Cech NB. Targeted and untargeted analysis of secondary metabolites to monitor growth and quorum sensing inhibition for methicillin-resistant Staphylococcus aureus (MRSA). Journal of Microbiological Methods. 106000. PMID 32649968 DOI: 10.1016/J.Mimet.2020.106000  0.429
2020 Khin M, Cech NB, Kellogg JJ, Caesar LK. Chemical Evaluation of the Effects of Storage Conditions on the Botanical Goldenseal using Marker-based and Metabolomics Approaches. The Yale Journal of Biology and Medicine. 93: 265-275. PMID 32607087  0.639
2020 Flores-Bocanegra L, Raja HA, Graf TN, Augustinović M, Wallace ED, Hematian S, Kellogg JJ, Todd DA, Cech NB, Oberlies NH. The Chemistry of Kratom []: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids. Journal of Natural Products. PMID 32597657 DOI: 10.1021/Acs.Jnatprod.0C00257  0.651
2020 Wallace ED, Todd DA, Harnly JM, Cech NB, Kellogg JJ. Identification of adulteration in botanical samples with untargeted metabolomics. Analytical and Bioanalytical Chemistry. PMID 32347364 DOI: 10.1007/S00216-020-02678-6  0.671
2020 Brown MM, Kwiecinski JM, Mejia Cruz L, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel peptide from commensal blocks MRSA quorum sensing and protects host skin from damage. Antimicrobial Agents and Chemotherapy. PMID 32253213 DOI: 10.1128/Aac.00172-20  0.315
2020 Liigand J, Wang T, Kellogg J, Smedsgaard J, Cech N, Kruve A. Quantification for non-targeted LC/MS screening without standard substances. Scientific Reports. 10: 5808. PMID 32242073 DOI: 10.1038/S41598-020-62573-Z  0.666
2020 Kellogg JJ, Kvalheim OM, Cech NB. Composite score analysis for unsupervised comparison and network visualization of metabolomics data. Analytica Chimica Acta. 1095: 38-47. PMID 31864629 DOI: 10.1016/J.Aca.2019.10.029  0.649
2019 Rivera-Chávez J, Caesar L, Garcia-Salazar JJ, Raja HA, Cech NB, Pearce CJ, Oberlies NH. Mycopyranone: a 8,8'-binaphthopyranone with potent anti-MRSA activity from the fungus sp. Tetrahedron Letters. 60: 594-597. PMID 31598014 DOI: 10.1016/J.Tetlet.2019.01.029  0.344
2019 Caesar LK, Nogo S, Naphen CN, Cech NB. Simplify: A Mass Spectrometry Metabolomics Approach to Identify Additives and Synergists from Complex Mixtures. Analytical Chemistry. PMID 31365233 DOI: 10.1021/Acs.Analchem.9B02377  0.408
2019 Caesar LK, Cech NB. Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2. Natural Product Reports. PMID 31187844 DOI: 10.1039/C9Np00011A  0.393
2019 Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Reports. 27: 187-198.e6. PMID 30943400 DOI: 10.1016/J.Celrep.2019.03.018  0.355
2019 Caesar LK, Kellogg JJ, Kvalheim OM, Cech NB. Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures. Journal of Natural Products. PMID 30844279 DOI: 10.1021/Acs.Jnatprod.9B00176  0.693
2019 Knowles SL, Raja HA, Wright AJ, Lee AML, Caesar LK, Cech NB, Mead ME, Steenwyk JL, Ries LNA, Goldman GH, Rokas A, Oberlies NH. Mapping the Fungal Battlefield: Using Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions Between Fungi. Frontiers in Microbiology. 10: 285. PMID 30837981 DOI: 10.3389/Fmicb.2019.00285  0.342
2019 Paguigan ND, Rivera-Chávez J, Stempin JJ, Augustinović M, Noras AI, Raja HA, Todd DA, Triplett KD, Day C, Figueroa M, Hall PR, Cech NB, Oberlies NH. Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing. Journal of Natural Products. PMID 30730742 DOI: 10.1021/Acs.Jnatprod.8B00925  0.397
2019 Kellogg JJ, Paine MF, McCune JS, Oberlies NH, Cech NB. Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach. Natural Product Reports. PMID 30681109 DOI: 10.1039/C8Np00065D  0.665
2019 Curtin P, Kellogg J, Cech N, Gennings C. A random subset implementation of weighted quantile sum (WQSRS) regression for analysis of high-dimensional mixtures Communications in Statistics - Simulation and Computation. 1-16. DOI: 10.1080/03610918.2019.1577971  0.611
2018 Khin M, Jones AM, Cech NB, Caesar LK. Phytochemical Analysis and Antimicrobial Efficacy of against Extensively Drug-Resistant . Natural Product Communications. 13. PMID 31080542 DOI: 10.1177/1934578X1801301117  0.427
2018 Bruni R, Brighenti V, Caesar LK, Bertelli D, Cech NB, Pellati F. Analytical methods for the study of bioactive compounds from medicinally used Echinacea species. Journal of Pharmaceutical and Biomedical Analysis. 160: 443-477. PMID 30142565 DOI: 10.1016/J.Jpba.2018.07.044  0.413
2018 Wallace ED, Oberlies NH, Cech NB, Kellogg JJ. Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 30031041 DOI: 10.1016/J.Fct.2018.07.033  0.689
2018 Caesar LK, Kvalheim OM, Cech NB. Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics. Analytica Chimica Acta. 1021: 69-77. PMID 29681286 DOI: 10.1016/J.Aca.2018.03.013  0.354
2018 Caesar LK, Kellogg JJ, Kvalheim OM, Cech RA, Cech NB. Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei. Planta Medica. PMID 29571174 DOI: 10.1055/A-0590-5223  0.692
2018 Tian DD, Kellogg JJ, Okut N, Oberlies NH, Cech NB, Shen DD, McCune JS, Paine MF. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea () Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29467215 DOI: 10.1124/Dmd.117.079491  0.672
2017 Paharik AE, Parlet CP, Chung N, Todd DA, Rodriguez EI, Van Dyke MJ, Cech NB, Horswill AR. Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing. Cell Host & Microbe. 22: 746-756.e5. PMID 29199097 DOI: 10.1016/J.Chom.2017.11.001  0.349
2017 Britton ER, Kellogg JJ, Kvalheim OM, Cech NB. Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal). Journal of Natural Products. PMID 29091439 DOI: 10.1021/Acs.Jnatprod.7B00654  0.728
2017 Gulledge TV, Collette NM, Mackey E, Johnstone SE, Moazami Y, Todd DA, Moeser AJ, Pierce JG, Cech NB, Laster SM. Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide. Journal of Ethnopharmacology. PMID 29042288 DOI: 10.1016/J.Jep.2017.10.012  0.308
2017 Kellogg JJ, Wallace ED, Graf TN, Oberlies NH, Cech NB. Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics. Journal of Pharmaceutical and Biomedical Analysis. 145: 604-610. PMID 28787673 DOI: 10.1016/J.Jpba.2017.07.027  0.687
2017 Leyte-Lugo M, Britton ER, Foil DH, Brown AR, Todd DA, Rivera-Chávez J, Oberlies NH, Cech NB. Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis). Phytochemistry Letters. 20: 54-60. PMID 28736584 DOI: 10.1016/J.Phytol.2017.03.012  0.417
2017 Todd DA, Parlet CP, Crosby HA, Malone CL, Heilmann KP, Horswill AR, Cech NB. Targeting quorum sensing signal biosynthesis to fight antibiotic resistant infections: Ambuic acid as a model inhibitor. Antimicrobial Agents and Chemotherapy. PMID 28607020 DOI: 10.1128/Aac.00263-17  0.375
2017 Kellogg JJ, Graf TN, Paine MF, McCune JS, Kvalheim OM, Oberlies NH, Cech NB. Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study. Journal of Natural Products. PMID 28453261 DOI: 10.1021/Acs.Jnatprod.6B01156  0.683
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis). Phytochemistry Letters. 17: 219-225. PMID 28603575 DOI: 10.1016/J.Phytol.2016.07.031  0.8
2016 Kaur A, Oberhofer M, Juzumaite M, Raja HA, Gulledge TV, Kao D, Faeth SH, Laster SM, Oberlies NH, Cech NB. Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells. Natural Product Communications. 11: 1143-1146. PMID 28479944 DOI: 10.1177/1934578X1601100827  0.398
2016 Brooks WC, Paguigan ND, Raja HA, Moy FJ, Cech NB, Pearce CJ, Oberlies NH. qNMR for profiling the production of fungal secondary metabolites. Magnetic Resonance in Chemistry : Mrc. PMID 28024162 DOI: 10.1002/Mrc.4571  0.384
2016 Caesar LK, Cech NB. A Review of the Medicinal Uses and Pharmacology of Ashitaba. Planta Medica. PMID 27399234 DOI: 10.1055/S-0042-110496  0.364
2016 Todd DA, Zich DB, Ettefagh KA, Kavanaugh JS, Horswill AR, Cech NB. Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition. Journal of Microbiological Methods. PMID 27237773 DOI: 10.1016/J.Mimet.2016.05.024  0.414
2016 Graf TN, Cech NB, Polyak SJ, Oberlies NH. A validated UHPLC-tandem mass spectrometry method for quantitative analysis of flavonolignans in milk thistle (Silybum marianum) extracts. Journal of Pharmaceutical and Biomedical Analysis. 126: 26-33. PMID 27136284 DOI: 10.1016/J.Jpba.2016.04.028  0.405
2016 Kellogg JJ, Todd DA, Egan JM, Raja HA, Oberlies NH, Kvalheim OM, Cech NB. Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds. Journal of Natural Products. PMID 26841051 DOI: 10.1021/Acs.Jnatprod.5B01014  0.799
2016 Caesar L, Kellogg J, Cech R, Cech N. An integrated approach for assessing antimicrobial constituents from Angelica keiskei Koidzumi Planta Medica. 81: S1-S381. DOI: 10.1055/S-0036-1596185  0.628
2016 Kellogg J, Kvalheim O, Cech N. Biochemometric analysis reveals complimentary bacterial inhibitory functionalities of the medicinal lichen Usnea barbata Planta Medica. 81: S1-S381. DOI: 10.1055/S-0036-1596184  0.658
2016 Britton E, Kellogg J, Kvalheim O, Cech N. New strategies to identify synergists from Hydrastis canadensis (goldenseal) Planta Medica. 81: S1-S381. DOI: 10.1055/S-0036-1596182  0.619
2016 Egan JM, Kaur A, Raja HA, Kellogg JJ, Oberlies NH, Cech NB. Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis) Phytochemistry Letters. 17: 219-225. DOI: 10.1016/j.phytol.2016.07.031  0.798
2015 Britton ER, Ibberson CB, Horswill AR, Cech NB. A new mass spectrometry based bioassay for the direct assessment of hyaluronidase activity and inhibition. Journal of Microbiological Methods. 119: 163-167. PMID 26519769 DOI: 10.1016/J.Mimet.2015.10.019  0.375
2015 Jarmusch AK, Musso AM, Shymanovich T, Jarmusch SA, Weavil MJ, Lovin ME, Ehrmann BM, Saari S, Nichols DE, Faeth SH, Cech NB. Comparison of electrospray ionization and atmospheric pressure photoionization liquid chromatography mass spectrometry methods for analysis of ergot alkaloids from endophyte-infected sleepygrass (Achnatherum robustum). Journal of Pharmaceutical and Biomedical Analysis. 117: 11-17. PMID 26340558 DOI: 10.1016/J.Jpba.2015.08.031  0.783
2015 Raja HA, Kaur A, El-Elimat T, Figueroa M, Kumar R, Deep G, Agarwal R, Faeth SH, Cech NB, Oberlies NH. Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle). Mycology. 6: 8-27. PMID 26000195 DOI: 10.1080/21501203.2015.1009186  0.386
2015 Brown AR, Ettefagh KA, Todd D, Cole PS, Egan JM, Foil DH, Graf TN, Schindler BD, Kaatz GW, Cech NB. A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition. Plos One. 10: e0124814. PMID 25961825 DOI: 10.1371/Journal.Pone.0124814  0.796
2015 Todd DA, Gulledge TV, Britton ER, Oberhofer M, Leyte-Lugo M, Moody AN, Shymanovich T, Grubbs LF, Juzumaite M, Graf TN, Oberlies NH, Faeth SH, Laster SM, Cech NB. Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. Plos One. 10: e0124276. PMID 25933416 DOI: 10.1371/Journal.Pone.0124276  0.382
2015 Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrobial Agents and Chemotherapy. 59: 2223-35. PMID 25645827 DOI: 10.1128/Aac.04564-14  0.359
2015 Bussey RO, Kaur A, Todd DA, Egan JM, El-Elimat T, Graf TN, Raja HA, Oberlies NH, Cech NB. Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica). Phytochemistry Letters. 11: 202-208. PMID 25642298 DOI: 10.1016/J.Phytol.2014.12.013  0.806
2015 Shymanovich T, Saari S, Lovin ME, Jarmusch AK, Jarmusch SA, Musso AM, Charlton ND, Young CA, Cech NB, Faeth SH. Alkaloid variation among epichloid endophytes of sleepygrass (Achnatherum robustum) and consequences for resistance to insect herbivores. Journal of Chemical Ecology. 41: 93-104. PMID 25501262 DOI: 10.1007/S10886-014-0534-X  0.773
2015 Egan J, Kaur A, Raja H, Brown A, Oberlies N, Cech N. Prevalence of antimicrobial fungal metabolites in Hydrastis canadensis crude extracts Planta Medica. 81. DOI: 10.1055/S-0035-1556312  0.792
2015 Kao D, Raja H, Paguigan N, Cech N, Oberlies N. Triggering epipolythiodioxopiperazine alkaloid biosynthesis in fungal endophytes of Goldenseal (Hydrastis Canadensis) Planta Medica. 81. DOI: 10.1055/S-0035-1556309  0.363
2015 Britton E, Ibberson C, Leyte-Lugo M, Bussey III R, Raja H, Oberlies N, Horswill A, Cech N. A new anti-virulence strategy against pathogenic bacteria: Targeting spreading factors Planta Medica. 81. DOI: 10.1055/S-0035-1556215  0.406
2015 Todd D, Zich D, Horswill A, Cech N. A novel bioassay to identify anti-virulence leads against gram-positive bacterial pathogens Planta Medica. 81. DOI: 10.1055/S-0035-1556180  0.306
2015 Kellogg J, Todd D, Egan J, Raja H, Oberlies N, Kvalheim O, Cech N. Chemometric-directed bioexploration of natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556170  0.746
2014 Alfaro CM, Uwakweh AO, Todd DA, Ehrmann BM, Cech NB. Investigations of analyte-specific response saturation and dynamic range limitations in atmospheric pressure ionization mass spectrometry. Analytical Chemistry. 86: 10639-45. PMID 25268329 DOI: 10.1021/Ac502984A  0.315
2014 Figueroa M, Jarmusch AK, Raja HA, El-Elimat T, Kavanaugh JS, Horswill AR, Cooks RG, Cech NB, Oberlies NH. Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. Journal of Natural Products. 77: 1351-8. PMID 24911880 DOI: 10.1021/Np5000704  0.702
2014 Bussey RO, Sy-Cordero AA, Figueroa M, Carter FS, Falkinham JO, Oberlies NH, Cech NB. Antimycobacterial furofuran lignans from the roots of Anemopsis californica. Planta Medica. 80: 498-501. PMID 24687738 DOI: 10.1055/S-0034-1368352  0.433
2014 El-Elimat T, Raja HA, Graf TN, Faeth SH, Cech NB, Oberlies NH. Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum). Journal of Natural Products. 77: 193-9. PMID 24456525 DOI: 10.1021/Np400955Q  0.406
2014 Britton E, Todd D, Leyte-Lugo M, Gulledge T, Grubbs L, Oberhofer M, Faeth S, Laster S, Cech N. Unraveling immunomodulatory activities of complex Echinacea purpurea extracts Planta Medica. 80. DOI: 10.1055/S-0034-1382726  0.334
2014 Graf T, Polyak S, Ehrmann B, Cech N, Oberlies N. Validated UPLC-UV/MS method for the quantitation of flavonolignans in milk thistle (Silybum mariaum) extracts Planta Medica. 80. DOI: 10.1055/S-0034-1382666  0.357
2014 Egan J, Kaur A, Raja H, Brown A, Oberlies N, Cech N. Antimicrobial secondary metabolites from fungal endophytes of goldenseal (Hydrastis canadensis) Planta Medica. 80. DOI: 10.1055/S-0034-1382413  0.789
2014 Kao D, Kaur A, Raja H, El-Elimat T, Oberhofer M, Juzumaite M, Gulledge T, Laster S, Cech N, Faeth S, Oberlies N. Chemical investigation of fungal endophytes from Echinacea purpurea Planta Medica. 80. DOI: 10.1055/S-0034-1382406  0.301
2013 Cech NB, Horswill AR. Small-molecule quorum quenchers to prevent Staphylococcus aureus infection. Future Microbiology. 8: 1511-4. PMID 24266350 DOI: 10.2217/Fmb.13.134  0.335
2013 El-Elimat T, Figueroa M, Ehrmann BM, Cech NB, Pearce CJ, Oberlies NH. High-resolution MS, MS/MS, and UV database of fungal secondary metabolites as a dereplication protocol for bioactive natural products. Journal of Natural Products. 76: 1709-16. PMID 23947912 DOI: 10.1021/Np4004307  0.412
2013 Junio HA, Todd DA, Ettefagh KA, Ehrmann BM, Kavanaugh JS, Horswill AR, Cech NB. Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography-high resolving power mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 930: 7-12. PMID 23703543 DOI: 10.1016/J.Jchromb.2013.04.019  0.794
2013 Bame JR, Graf TN, Junio HA, Bussey RO, Jarmusch SA, El-Elimat T, Falkinham JO, Oberlies NH, Cech RA, Cech NB. Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor. Planta Medica. 79: 327-9. PMID 23468310 DOI: 10.1055/S-0032-1328259  0.783
2013 Bussey III R, El-Elimat T, Kaur A, Raja H, Oberlies N, Cech N. Antimicrobial Endophytes from the Antimicrobial Botanical Yerba mansa (Anemposis californica) Planta Medica. 79. DOI: 10.1055/S-0033-1348701  0.365
2013 Raja H, Kaur A, Figueroa M, El-Elimat T, Cech N, Faeth S, Oberlies N. Mycology and Chemical Investigations of Fungal Endophytes from Medicinal Herbs (Milk Thistle and Goldenseal) Planta Medica. 79. DOI: 10.1055/S-0033-1348664  0.329
2012 Cech NB, Junio HA, Ackermann LW, Kavanaugh JS, Horswill AR. Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA). Planta Medica. 78: 1556-61. PMID 22814821 DOI: 10.1055/S-0032-1315042  0.811
2012 Wan C, Yuan T, Li L, Kandhi V, Cech NB, Xie M, Seeram NP. Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems. Bioorganic & Medicinal Chemistry Letters. 22: 597-600. PMID 22079755 DOI: 10.1016/J.Bmcl.2011.10.073  0.324
2012 Ettefagh K, Todd D, Junio H, Horswill A, Cech N. Mass spectrometric detection of virulence factors from methecillin-resistant Staphylococcus aureus (MRSA) Planta Medica. 78. DOI: 10.1055/S-0032-1321236  0.772
2012 Jarmusch S, Ehrmann B, Saari S, Shymanovich T, Faeth S, Cech N. Comparison of mass spectrometric ionization techniques for analysis of bioactive loline alkaloids Planta Medica. 78. DOI: 10.1055/S-0032-1321235  0.746
2012 Cech NB, Enke CG. Selectivity in Electrospray Ionization Mass Spectrometry Electrospray and Maldi Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications: Second Edition. 49-73. DOI: 10.1002/9780470588901.ch2  0.513
2011 Yuan T, Wan C, González-Sarrías A, Kandhi V, Cech NB, Seeram NP. Phenolic glycosides from sugar maple (Acer saccharum) bark. Journal of Natural Products. 74: 2472-6. PMID 22032697 DOI: 10.1021/Np200678N  0.343
2011 Junio HA, Sy-Cordero AA, Ettefagh KA, Burns JT, Micko KT, Graf TN, Richter SJ, Cannon RE, Oberlies NH, Cech NB. Synergy-directed fractionation of botanical medicines: a case study with goldenseal (Hydrastis canadensis). Journal of Natural Products. 74: 1621-9. PMID 21661731 DOI: 10.1021/Np200336G  0.821
2011 Ettefagh KA, Burns JT, Junio HA, Kaatz GW, Cech NB. Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition. Planta Medica. 77: 835-40. PMID 21157683 DOI: 10.1055/S-0030-1250606  0.806
2011 Cebrián-Torrejón G, Spelman K, Leblanc K, Muñoz-Durango K, Gutiérrez ST, Ferreira ME, de Arias AR, Figadère B, Maciuk AFA, Grellier P, Cech NB, Poupon E. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. Angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum Brazilian Journal of Pharmacognosy. 21: 652-661. DOI: 10.1590/S0102-695X2011005000104  0.416
2010 Cech NB, Kandhi V, Davis JM, Hamilton A, Eads D, Laster SM. Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells. International Immunopharmacology. 10: 1268-78. PMID 20674883 DOI: 10.1016/J.Intimp.2010.07.009  0.347
2010 Bae SS, Ehrmann BM, Ettefagh KA, Cech NB. A validated liquid chromatography-electrospray ionization-mass spectrometry method for quantification of spilanthol in Spilanthes acmella (L.) Murr. Phytochemical Analysis : Pca. 21: 438-43. PMID 20310072 DOI: 10.1002/Pca.1215  0.349
2010 Benson JM, Pokorny AJ, Rhule A, Wenner CA, Kandhi V, Cech NB, Shepherd DM. Echinacea purpurea extracts modulate murine dendritic cell fate and function. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 48: 1170-7. PMID 20149833 DOI: 10.1016/J.Fct.2010.02.007  0.359
2009 Spelman K, Wetschler MH, Cech NB. Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS. Journal of Pharmaceutical and Biomedical Analysis. 49: 1141-9. PMID 19321283 DOI: 10.1016/J.Jpba.2009.02.011  0.403
2008 Ehrmann BM, Henriksen T, Cech NB. Relative importance of basicity in the gas phase and in solution for determining selectivity in electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 19: 719-28. PMID 18325781 DOI: 10.1016/J.Jasms.2008.01.003  0.31
2008 Cech N, Junio H, Tarney K, Cannon R, Graf T, Oberlies N. A role for non-alkaloidal constitutes in the antibacterial activity of Hydrastis canadensis Planta Medica. 74. DOI: 10.1055/S-0028-1083909  0.813
2007 Raner GM, Cornelious S, Moulick K, Wang Y, Mortenson A, Cech NB. Effects of herbal products and their constituents on human cytochrome P450(2E1) activity. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 45: 2359-65. PMID 17658211 DOI: 10.1016/J.Fct.2007.06.012  0.327
2006 Cech NB, Tutor K, Doty BA, Spelman K, Sasagawa M, Raner GM, Wenner CA. Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: production of novel metabolites and changes in immunomodulatory activity. Planta Medica. 72: 1372-7. PMID 17054047 DOI: 10.1055/S-2006-951718  0.328
2006 Sasagawa M, Cech NB, Gray DE, Elmer GW, Wenner CA. Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells. International Immunopharmacology. 6: 1214-21. PMID 16714226 DOI: 10.1016/J.Intimp.2006.02.003  0.314
2006 Cech NB, Eleazer MS, Shoffner LT, Crosswhite MR, Davis AC, Mortenson AM. High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts. Journal of Chromatography. A. 1103: 219-28. PMID 16298376 DOI: 10.1016/J.Chroma.2005.11.008  0.381
2005 Henriksen T, Juhler RK, Svensmark B, Cech NB. The relative influences of acidity and polarity on responsiveness of small organic molecules to analysis with negative ion electrospray ionization mass spectrometry (ESI-MS). Journal of the American Society For Mass Spectrometry. 16: 446-55. PMID 15792713 DOI: 10.1016/J.Jasms.2004.11.021  0.302
2001 Cech NB, Enke CG. Practical implications of some recent studies in electrospray ionization fundamentals. Mass Spectrometry Reviews. 20: 362-87. PMID 11997944 DOI: 10.1002/Mas.10008  0.554
2001 Cech NB, Enke CG. Effect of affinity for droplet surfaces on the fraction of analyte molecules charged during electrospray droplet fission. Analytical Chemistry. 73: 4632-9. PMID 11605841 DOI: 10.1021/Ac001267J  0.535
2001 Cech NB, Krone JR, Enke CG. Electrospray ionization detection of inherently nonresponsive epoxides by peptide binding. Rapid Communications in Mass Spectrometry : Rcm. 15: 1040-4. PMID 11404839 DOI: 10.1002/Rcm.337  0.551
2001 Cech NB, Krone JR, Enke CG. Predicting electrospray response from chromatographic retention time. Analytical Chemistry. 73: 208-13. PMID 11199967 DOI: 10.1021/Ac0006019  0.538
2000 Amad MH, Cech NB, Jackson GS, Enke CG. Importance of gas-phase proton affinities in determining the electrospray ionization response for analytes and solvents. Journal of Mass Spectrometry : Jms. 35: 784-9. PMID 10934432 DOI: 10.1002/1096-9888(200007)35:7<784::Aid-Jms17>3.0.Co;2-Q  0.535
2000 Cech NB, Enke CG. Relating electrospray ionization response to nonpolar character of small peptides. Analytical Chemistry. 72: 2717-23. PMID 10905298 DOI: 10.1021/Ac9914869  0.55
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