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Geng Wu, Ph.D. - Publications

Affiliations: 
Princeton University, Princeton, NJ 
Area:
structural and molecular mechanisms involved in tumorigenesis
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tang H, Zhang K, Hu H, Wu G, Wang W, Zhu X, Liu G, Xu P. Molecular Deceleration Regulates Toxicant Release to Prevent Cell Damage in Pseudomonas putida S16 (DSM 28022). Mbio. 11. PMID 32873764 DOI: 10.1128/Mbio.02012-20  0.372
2020 Yu H, Li J, Liu G, Zhao G, Wang Y, Hu W, Deng Z, Wu G, Gan J, Zhao YL, He X. DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses. Nucleic Acids Research. PMID 32621606 DOI: 10.1093/Nar/Gkaa574  0.386
2020 Liu L, Jiang S, Xing M, Chen C, Lai C, Li N, Liu G, Wu D, Gao H, Hong L, Tan P, Chen S, Deng Z, Wu G, Wang L. Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. Mbio. 11. PMID 32345643 DOI: 10.1128/Mbio.00488-20  0.417
2020 Xiong X, Wu G, Wei Y, Liu L, Zhang Y, Su R, Jiang X, Li M, Gao H, Tian X, Zhang Y, Hu L, Chen S, Tang Y, Jiang S, et al. SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nature Microbiology. PMID 32251370 DOI: 10.2210/Pdb6Jiv/Pdb  0.307
2019 Hu H, Wang L, Wang W, Wu G, Tao F, Xu P, Deng Z, Tang H. Regulatory Mechanism of Nicotine Degradation in . Mbio. 10. PMID 31164460 DOI: 10.1128/Mbio.00602-19  0.338
2018 Liu G, Fu W, Zhang Z, He Y, Yu H, Wang Y, Wang X, Zhao YL, Deng Z, Wu G, He X. Structural basis for the recognition of sulfur in phosphorothioated DNA. Nature Communications. 9: 4689. PMID 30409991 DOI: 10.1038/S41467-018-07093-1  0.378
2018 Yu H, Liu G, Zhao G, Hu W, Wu G, Deng Z, He X. Identification of a conserved DNA sulfur recognition domain by characterizing the phosphorothioate-specific endonuclease SprMcrA from Streptomyces pristinaespiralis. Molecular Microbiology. PMID 30184284 DOI: 10.1111/Mmi.14118  0.35
2017 Mu Z, Wang L, Deng W, Wang J, Wu G. Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane. Cell Discovery. 3: 17049. PMID 29285400 DOI: 10.2210/Pdb5Yk3/Pdb  0.392
2017 Kulaberoglu Y, Lin K, Holder M, Gai Z, Gomez M, Assefa Shifa B, Mavis M, Hoa L, Sharif AAD, Lujan C, Smith ESJ, Bjedov I, Tapon N, Wu G, Hergovich A. Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control. Nature Communications. 8: 695. PMID 28947795 DOI: 10.2210/Pdb5Xqz/Pdb  0.301
2017 Qian T, Wo J, Zhang Y, Song Q, Feng G, Luo R, Lin S, Wu G, Chen HF. Crystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode. Scientific Reports. 7: 40254. PMID 28074848 DOI: 10.1038/Srep40254  0.434
2016 Gai Z, Wang Q, Yang C, Wang L, Deng W, Wu G. Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway. Cell Discovery. 2: 16051. PMID 28066558 DOI: 10.1038/Celldisc.2016.51  0.426
2016 Zhao G, Chen C, Xiong W, Gao T, Deng Z, Wu G, He X. Structural basis of the substrate preference towards CMP for a thymidylate synthase MilA involved in mildiomycin biosynthesis. Scientific Reports. 6: 39675. PMID 28000775 DOI: 10.1038/Srep39675  0.38
2016 Zhang K, Wu G, Tang H, Hu C, Shi T, Xu P. Structural basis for the transcriptional repressor NicR2 in nicotine degradation from Pseudomonas. Molecular Microbiology. PMID 27741553 DOI: 10.1111/Mmi.13548  0.435
2016 Gai Z, Chu W, Deng W, Li W, Li H, He A, Nellist M, Wu G. Structure of the TBC1D7-TSC1 complex reveals that TBC1D7 stabilizes dimerization of the TSC1 C-terminal coiled coil region. Journal of Molecular Cell Biology. PMID 26798146 DOI: 10.1093/Jmcb/Mjw001  0.365
2015 Zhang Z, Akyildiz S, Xiao Y, Gai Z, An Y, Behrens J, Wu G. Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners. Cell Discovery. 1: 15016. PMID 27462415 DOI: 10.1038/Celldisc.2015.16  0.327
2015 Jiang Y, Tang H, Wu G, Xu P. Functional Identification of a Novel Gene, moaE, for 3-Succinoylpyridine Degradation in Pseudomonas putida S16. Scientific Reports. 5: 13464. PMID 26304596 DOI: 10.1038/Srep13464  0.307
2015 Zhang Y, An J, Yang GY, Bai A, Zheng B, Lou Z, Wu G, Ye W, Chen HF, Feng Y, Manco G. Active site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426. Plos One. 10: e0115130. PMID 25706379 DOI: 10.1371/Journal.Pone.0115130  0.357
2015 Liu G, Zhang Z, Zhao G, Deng Z, Wu G, He X. Crystallization and preliminary X-ray analysis of the type IV restriction endonuclease ScoMcrA from Streptomyces coelicolor, which cleaves both Dcm-methylated DNA and phosphorothioated DNA. Acta Crystallographica. Section F, Structural Biology Communications. 71: 57-60. PMID 25615970 DOI: 10.1107/S2053230X14025801  0.319
2014 Zhao G, Wu G, Zhang Y, Liu G, Han T, Deng Z, He X. Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry. Nucleic Acids Research. 42: 8115-24. PMID 24920828 DOI: 10.1093/Nar/Gku486  0.442
2014 Wang H, Zhang Y, Zhang Z, Jin WL, Wu G. Purification, crystallization and preliminary X-ray analysis of the inverse F-BAR domain of the human srGAP2 protein. Acta Crystallographica. Section F, Structural Biology Communications. 70: 123-6. PMID 24419634 DOI: 10.1107/S2053230X13033712  0.329
2014 Wu G, Chen D, Tang H, Ren Y, Chen Q, Lv Y, Zhang Z, Zhao YL, Yao Y, Xu P. Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases. Molecular Microbiology. 91: 1009-21. PMID 24397579 DOI: 10.1111/Mmi.12511  0.335
2013 Zhang Y, Fu L, Qi X, Zhang Z, Xia Y, Jia J, Jiang J, Zhao Y, Wu G. Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nature Communications. 4: 2608. PMID 24217340 DOI: 10.1038/Ncomms3608  0.355
2013 Chen D, Tang H, Lv Y, Zhang Z, Shen K, Lin K, Zhao YL, Wu G, Xu P. Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside. Molecular Microbiology. 87: 1237-44. PMID 23347155 DOI: 10.1111/Mmi.12163  0.377
2012 Chen F, Zhang Z, Lin K, Qian T, Zhang Y, You D, He X, Wang Z, Liang J, Deng Z, Wu G. Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation. Plos One. 7: e36635. PMID 22570733 DOI: 10.1371/Journal.Pone.0036635  0.435
2012 Hu W, Wang C, Liang J, Zhang T, Hu Z, Wang Z, Lan W, Li F, Wu H, Ding J, Wu G, Deng Z, Cao C. Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification. Cell Research. 22: 1203-6. PMID 22525332 DOI: 10.1038/Cr.2012.66  0.333
2012 Zhang Z, Chen L, Gao L, Lin K, Zhu L, Lu Y, Shi X, Gao Y, Zhou J, Xu P, Zhang J, Wu G. Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Research. 22: 372-86. PMID 21788986 DOI: 10.1038/Cr.2011.119  0.405
2011 Chen F, Lin K, Zhang Z, Chen L, Shi X, Cao C, Wang Z, Liang J, Deng Z, Wu G. Purification, crystallization and preliminary X-ray analysis of the DndE protein from Salmonella enterica serovar Cerro 87, which is involved in DNA phosphorothioation. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1440-2. PMID 22102252 DOI: 10.1107/S1744309111036694  0.35
2011 Zhang Z, Lin K, Gao L, Chen L, Shi X, Wu G. Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility. Biochemical and Biophysical Research Communications. 412: 732-6. PMID 21871439 DOI: 10.1016/J.Bbrc.2011.08.044  0.414
2011 Zhang Z, Li H, Chen L, Lu X, Zhang J, Xu P, Lin K, Wu G. Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. Plos One. 6: e23507. PMID 21858148 DOI: 10.1371/Journal.Pone.0023507  0.41
2011 Huang Z, Zhu L, Cao Y, Wu G, Liu X, Chen Y, Wang Q, Shi T, Zhao Y, Wang Y, Li W, Li Y, Chen H, Chen G, Zhang J. ASD: a comprehensive database of allosteric proteins and modulators. Nucleic Acids Research. 39: D663-9. PMID 21051350 DOI: 10.1093/Nar/Gkq1022  0.321
2005 Hao B, Zheng N, Schulman BA, Wu G, Miller JJ, Pagano M, Pavletich NP. Structural basis of the Cks1-dependent recognition of p27 Kip1 by the SCF Skp2 ubiquitin ligase Molecular Cell. 20: 9-19. PMID 16209941 DOI: 10.1016/J.Molcel.2005.09.003  0.6
2003 Wu G, Xu G, Schulman BA, Jeffrey PD, Harper JW, Pavletich NP. Structure of a β-TrCP1-Skp1-β-catenin complex: Destruction motif binding and lysine specificity of the SCFβ-TrCP1 ubiquitin ligase Molecular Cell. 11: 1445-1456. PMID 12820959 DOI: 10.1016/S1097-2765(03)00234-X  0.59
2000 Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, Shi Y. Structural basis of IAP recognition by Smac/DIABLO. Nature. 408: 1008-12. PMID 11140638 DOI: 10.1038/35050012  0.598
1999 Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature. 399: 549-57. PMID 10376594 DOI: 10.1038/21124  0.496
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